Senp2 (SUMO specific peptidase 2)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes Community Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Senp2 (SUMO specific peptidase 2) Rattus norvegicus

Analyze

Symbol:

Senp2

Name:

SUMO specific peptidase 2

RGD ID:

708378

Description:

Enables protein domain specific binding activity. Involved in dorsal/ventral axis specification and positive regulation of protein phosphorylation. Predicted to be located in cytoplasmic vesicle; cytosol; and nuclear body. Predicted to be part of nuclear pore. Predicted to colocalize with PML body. Orthologous to human SENP2 (SUMO specific peptidase 2); PARTICIPATES IN RNA transport pathway; Wnt signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Axam; Axin-associating molecule; LOC78973; sentrin-specific protease 2; sentrin/SUMO-specific protease SENP2; SUMO/sentrin specific peptidase 2; SUMO/sentrin specific protease 2; Sumo1/sentrin/SMT3 specific peptidase 2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SENP2 (SUMO specific peptidase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Senp2 (SUMO/sentrin specific peptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Senp2 (SUMO specific peptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SENP2 (SUMO specific peptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SENP2 (SUMO specific peptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Senp2 (SUMO specific peptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SENP2 (SUMO specific peptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SENP2 (SUMO specific peptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Senp2 (SUMO specific peptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	IQCD (IQ motif containing D)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Senp2 (SUMO/sentrin specific peptidase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SENP2 (SUMO specific peptidase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	senp2 (SUMO specific peptidase 2)	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	ULP1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ulp-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG32110	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Related Pseudogenes:

Senp2-ps6

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	78,981,429 - 79,018,274 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	78,981,432 - 79,018,238 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	87,718,539 - 87,752,630 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	80,372,185 - 80,406,276 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	79,432,886 - 79,466,977 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	82,627,973 - 82,664,702 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	82,630,436 - 82,664,630 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	85,721,099 - 85,755,217 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	81,225,720 - 81,259,934 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	81,283,308 - 81,317,523 (-)	NCBI
Celera	11	77,846,354 - 77,880,450 (-)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

Currarino syndrome (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-alpha-phellandrene (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (EXP)

5-aza-2'-deoxycytidine (ISO)

acetamide (EXP)

acetylcholine (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-phellandrene (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

carbamazepine (ISO)

chlorpyrifos (ISO)

Cuprizon (EXP)

decabromodiphenyl ether (EXP)

dexamethasone (EXP)

ethanol (ISO)

fenofibrate (ISO)

fenthion (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

glyphosate (ISO)

methylmercury chloride (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

Tributyltin oxide (EXP)

trichostatin A (ISO)

triphenyl phosphate (EXP)

trovafloxacin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dorsal/ventral axis specification (IDA)

fat cell differentiation (ISO,ISS)

heart development (ISO)

labyrinthine layer development (ISO)

mRNA transport (IEA)

negative regulation of DNA damage response, signal transduction by p53 class mediator (ISO)

negative regulation of protein binding (IDA)

negative regulation of protein ubiquitination (ISO)

negative regulation of signal transduction by p53 class mediator (ISO)

positive regulation of protein phosphorylation (IDA)

positive regulation of protein ubiquitination (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

protein destabilization (ISO)

protein desumoylation (ISO,ISS)

protein transport (IEA)

proteolysis (IEA)

regulation of DNA endoreduplication (ISO)

regulation of G1/S transition of mitotic cell cycle (ISO)

regulation of protein metabolic process (IDA)

spongiotrophoblast layer development (ISO)

trophoblast giant cell differentiation (ISO)

Wnt signaling pathway (IEA)

Cellular Component

cytoplasm (IEA,ISO)

cytoplasmic vesicle (ISO)

cytosol (ISO)

nuclear body (ISO)

nuclear membrane (IEA)

nuclear pore (ISO,ISS)

nucleus (IBA,ISO)

PML body (ISO,ISS)

Molecular Function

cysteine-type peptidase activity (IEA)

deSUMOylase activity (IBA,ISO,ISS)

protein binding (ISO)

protein domain specific binding (IPI)

SUMO-specific endopeptidase activity (ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA transport pathway (IEA)

Wnt signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Inhibition of Wnt signaling pathway by a novel axin-binding protein.	Kadoya T, etal., J Biol Chem 2000 Nov 24;275(47):37030-7.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11896061	PMID:11997515	PMID:12192048	PMID:12419228	PMID:15767674	PMID:16608850	PMID:17428805	PMID:17591783	PMID:19090619	PMID:20194620	PMID:20417598	PMID:21183956
PMID:21965678	PMID:22028379	PMID:29146736	PMID:29535048	PMID:34947973

Genomics

Comparative Map Data

Senp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	78,981,429 - 79,018,274 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	78,981,432 - 79,018,238 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	87,718,539 - 87,752,630 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	80,372,185 - 80,406,276 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	79,432,886 - 79,466,977 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	82,627,973 - 82,664,702 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	82,630,436 - 82,664,630 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	85,721,099 - 85,755,217 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	81,225,720 - 81,259,934 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	81,283,308 - 81,317,523 (-)	NCBI
Celera	11	77,846,354 - 77,880,450 (-)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

SENP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	185,586,295 - 185,633,551 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	185,582,496 - 185,633,551 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	185,304,083 - 185,351,339 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	186,786,725 - 186,831,583 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	186,786,732 - 186,831,585	NCBI
Celera	3	183,741,683 - 183,786,630 (+)	NCBI		Celera
Cytogenetic Map	3	q27.2	NCBI
HuRef	3	182,713,166 - 182,758,813 (+)	NCBI		HuRef
CHM1_1	3	185,267,116 - 185,311,866 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	188,402,099 - 188,449,380 (+)	NCBI		T2T-CHM13v2.0

Senp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	21,828,182 - 21,868,019 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	21,828,234 - 21,868,019 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	22,009,432 - 22,049,269 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	22,009,484 - 22,049,269 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	22,009,557 - 22,049,342 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	21,924,664 - 21,963,132 (+)	NCBI		MGSCv36	mm8
Celera	16	22,576,818 - 22,616,603 (+)	NCBI		Celera
Cytogenetic Map	16	B1	NCBI
cM Map	16	12.98	NCBI

Senp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	21,969,537 - 22,005,856 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	21,969,537 - 22,005,094 (-)	NCBI	ChiLan1.0	ChiLan1.0

SENP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	3	183,452,388 - 183,503,495 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	182,606,922 - 182,655,518 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	191,083,159 - 191,129,572 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	191,086,488 - 191,129,572 (+)	Ensembl	panpan1.1		panPan2

SENP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	18,325,373 - 18,357,152 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	18,325,553 - 18,356,192 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	22,411,070 - 22,442,872 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	18,235,175 - 18,266,937 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	18,235,165 - 18,266,935 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	18,270,590 - 18,302,404 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	18,266,749 - 18,298,733 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	18,496,165 - 18,528,163 (+)	NCBI		UU_Cfam_GSD_1.0

Senp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	118,160,861 - 118,198,599 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936578	4,248,244 - 4,290,418 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936578	4,252,718 - 4,290,452 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SENP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	123,429,995 - 123,471,926 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	123,429,915 - 123,469,913 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	132,967,994 - 133,007,559 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SENP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	3,805,916 - 3,853,529 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666063	12,558,692 - 12,605,920 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Senp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	71,068,112 - 71,100,225 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	71,068,112 - 71,100,121 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Senp2
112 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	631
Count of miRNA genes:	298
Interacting mature miRNAs:	378
Transcripts:	ENSRNOT00000002425
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat
70180	BpQTLcluster10	Blood pressure QTL cluster 10	3.19		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	11	34918041	79918041	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	40946188	82566702	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	44285759	82566702	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	54457534	86241447	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	55136729	82993457	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	56351424	86241447	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	59802794	82566545	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	59802794	82566553	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	60346590	86241447	Rat
1549848	Bvd6	Brain ventricular dilatation QTL 6	3.1	0.0001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	66113321	82169223	Rat
634339	Niddm50	Non-insulin dependent diabetes mellitus QTL 50	3.32		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	66422148	86241447	Rat
1354593	Stl12	Serum triglyceride level QTL 12	3.36		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	11	66422148	86241447	Rat
1354656	Bvd3	Brain ventricular dilatation QTL 3	3.64	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	69446070	82846715	Rat
10450831	Scl80	Serum cholesterol level QTL 80	4.7	0.01	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	11	76957131	83051965	Rat

Markers in Region

RH129168

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	78,982,823 - 78,983,015 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	82,629,368 - 82,629,559	NCBI	Rnor6.0
Rnor_5.0	11	85,720,031 - 85,720,222	UniSTS	Rnor5.0
RGSC_v3.4	11	81,224,652 - 81,224,843	UniSTS	RGSC3.4
Celera	11	77,845,286 - 77,845,477	UniSTS
Cytogenetic Map	11	q23	UniSTS

AW554757

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	179,164,647 - 179,164,781 (+)	MAPPER	mRatBN7.2
mRatBN7.2	11	78,983,168 - 78,983,302 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	82,629,713 - 82,629,846	NCBI	Rnor6.0
Rnor_6.0	2	193,836,197 - 193,836,330	NCBI	Rnor6.0
Rnor_5.0	11	85,720,376 - 85,720,509	UniSTS	Rnor5.0
Rnor_5.0	2	211,031,088 - 211,031,221	UniSTS	Rnor5.0
RGSC_v3.4	2	186,588,690 - 186,588,823	UniSTS	RGSC3.4
RGSC_v3.4	11	81,224,997 - 81,225,130	UniSTS	RGSC3.4
Celera	11	77,845,631 - 77,845,764	UniSTS
Celera	2	171,121,717 - 171,121,850	UniSTS
Cytogenetic Map	11	q23	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH141486

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	78,981,484 - 78,981,669 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	82,628,029 - 82,628,213	NCBI	Rnor6.0
Rnor_5.0	11	85,718,692 - 85,718,876	UniSTS	Rnor5.0
RGSC_v3.4	11	81,223,313 - 81,223,497	UniSTS	RGSC3.4
Celera	11	77,843,947 - 77,844,131	UniSTS
RH 3.4 Map	11	651.2	UniSTS
Cytogenetic Map	11	q23	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	26	40	24	19	24	5	8	74	35	41	11	5
Low		17	17	17		17	3	3					3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_023989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF260129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000002425 ⟹ ENSRNOP00000002425

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	78,981,432 - 79,018,238 (-)	Ensembl
Rnor_6.0 Ensembl	11	82,630,436 - 82,664,554 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000087105 ⟹ ENSRNOP00000071258

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	78,981,432 - 79,018,022 (-)	Ensembl
Rnor_6.0 Ensembl	11	82,636,983 - 82,664,630 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000098721 ⟹ ENSRNOP00000081876

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	78,981,432 - 79,016,674 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000112722 ⟹ ENSRNOP00000091248

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	78,981,432 - 79,014,877 (-)	Ensembl

RefSeq Acc Id:

NM_023989 ⟹ NP_076479

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	78,983,892 - 79,018,143 (-)	NCBI
Rnor_6.0	11	82,630,436 - 82,664,554 (-)	NCBI
Rnor_5.0	11	85,721,099 - 85,755,217 (-)	NCBI
RGSC_v3.4	11	81,225,720 - 81,259,934 (-)	RGD
Celera	11	77,846,354 - 77,880,450 (-)	RGD

Sequence:

show sequence

CGCTGCTGCTCAGGCCTGGAATGTACAGATGGCTGACTAAGGTTCTCGGCACCATTCTTCGCTT
GTGTGAGCGGCCCGCGCCCGGGGCCCGCGCCCTGCTCAAGAGGCGGCGCTCCAGCAGCTCTCTG
TTTTCTACTGCAGTGGACACTGATGAAATCCCAGCTAAAAGACCAAGACTAGATTGCTTCATTC
ACCAAGTGAAGAACAGTCTCTACAATGCGGCCAGCTTATTTGGATTCCCATTCCAGCTGACCAC
CAAACCCATGGTGTCTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTGTTC
TCGAACTCTCCCTCCTGTGAACTGACGACTTCTGGATCCTGCAGCAGCATGCTGAAGCTGGGTA
ATAAATCTCCTAATGGAATAAGTGACTATCCAAAGATCAGAGTGACAGTGGCCCGAGATCAGCC
ACGGAGAGTCCTGCCTTCCTTTGGTTTTACATTGAAATCAGAAGGCTATAATAGAAGACCAAGT
GGCCGTCGCCATAGCAAAAGCAATCCAGAGAGTTCCTTACCGTGGAAACCTCAGGAGCAAGGTG
TAACAGAGATGATTTCTGAAGAGGGTGGCAAGGGTGCAAGGCGTCCCCATTGCACCGTGGAGGA
GGGTGTCCAAAAGGACGAAAGAGAAAAATACCTAAAGTTATTGGAGCGTCTTAAAGAGGGTGCT
CACGGAAGCACTTTTCCTCCTGCAGTTTCACATCATAGTTCTCAGAGAACGCAGATGGACACAT
TAAAGACCAAAGGCTGGATGGAAGAACAGAATCATGGAGTCAGAACAACCCATTTGGTTCCCAA
ACAGTATAGAGTTGTTGAAACAAGAGGACCTCTCTGTTCAGTGAGAAGTGAAAAGAGGTATTCA
AAAGGAAAAGCTGACACAGAGAAGGTGGTGGGACTCCGATTTGAAAAGGACGGTACAAGAGGAC
ACCAGTTGGAGCCTGATCTGTCAGAAGAAGTGTCTGCCCGGCTTCGCCTGGGAAGTGGAAGCAA
TGGCCTACTCAGAAGGAAAATATCAGTGCTTGAGGCAAAGGAAAAGAACTTCCCAAGCAAAGAG
AAGGACAGAAGAACAGAAGATCTCTTTGAACTTACAGAGGACATGGAAAAGGAAATCAGTAATG
CCCTGGGCCATGGTCCTCCAGATGAGATTTTGAGCAGCGCTTTCAAGTTACGAATCACCCGTGG
AGATATCCAGACCTTAAAGAACTATCACTGGCTCAATGATGAGGTCATTAATTTTTATATGAAT
CTTTTAGTGGAGAGGAGTAAAAAGCAAGGCTACCCAGCACTTCATGCACTCAGTACATTCTTCT
ATCCTAAATTAAAGTCTGGAGGTTACCAAGCAGTGAAAAGATGGACCAAAGGGGTGAATCTCTT
CGATCAAGAACTTGTTCTGGTTCCTATTCATCGGAAGGTACATTGGAGCCTGGTGGTGATGGAC
CTAAGAAAAAAGTGTCTTAAATATCTGGATTCTATGGGACAAAAAGGCCACAGGATCTGTGAGA
TTCTTCTTCAGTATTTACAGGACGAAAGCAAGACCAAAAGAAATACAGATCTCAATCTCTTAGA
GTGGACCCACTACAGCATGAAGCCACATGAGATTCCTCAACAGTTGAATGGGAGTGATTGTGGA
ATGTTTACTTGTAAATACGCAGATTATATTTCTAGGGACAAACCTATCACATTCACTCAGCACC
AGATGCCTCTCTTCCGGAAGAAGATGGTGTGGGAAATCCTTCACCAGCAGTTGCTGTGACAATG
CCCCGCCTGGTCTTCT

hide sequence

RefSeq Acc Id:

XM_008768805 ⟹ XP_008767027

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	78,981,429 - 79,018,274 (-)	NCBI
Rnor_6.0	11	82,627,973 - 82,664,702 (-)	NCBI

Sequence:

show sequence

GAGTCCTCCCATAGCCCAGGGAACGTTGAATCTGAGGGCCCTCTGATGGCGTCACAAACCCGCG
CCTGATCCTGGCTACGGCCGAAGCGGCGAAGGCGGCAGCGGCGGCGACAGCTCTGGGGTTCGCG
TCTCGGGGTGTGTCGGCCGCCGCTGCTGCTCAGGCCTGGAATGTACAGATGGCTGACTAAGGTT
CTCGGCACCATTCTTCGCTTGTGTGAGCGGCCCGCGCCCGGGGCCCGCGCCCTGCTCAAGAGGC
GGCGCTCCAGCAGCTCTCTGTTTTCTACTGCAGTGGACACTGATGAAATCCCAGCTAAAAGACC
AAGACTAGATTGCTTCATTCACCAAGTGAAGAACAGTCTCTACAATGCGGCCAGCTTATTTGGA
TTCCCATTCCAGCTGACCACCAAACCCATGGTGTCTTCTGCTTGTAATGGAACACGGAATGTGG
CCCCTTCAGGAGAGGTGTTCTCGAACTCTCCCTCCTGTGAACTGACGACTTCTGGATCCTGCAG
CAGCATGCTGAAGCTGGGTAATAAATCTCCTAATGGAATAAGTGACTATCCAAAGATCAGAGTG
ACAGTGGCCCGAGATCAGCCACGGAGAGTCCTGCCTTCCTTTGGTTTTACATTGAAATCAGAAG
GCTATAATAGAAGACCAAGTGGCCGTCGCCATAGCAAAAGCAATCCAGAGAGTTCCTTACCGTG
GAAACCTCAGGAGCAAGGTGTAACAGAGATGATTTCTGAAGAGGGTGGCAAGGGTGCGAGGCGT
CCCCATTGCACCGTGGAGGAGGGTGTCCAAAAGGACGAAAGAGAAAAATACCTAAAGTTATTGG
AGCGTCTTAAAGAGGGTGCTCACGGAAGCACTTTTCCTCCTGCAGTTTCACATCATAGTTCTCA
GAGAACGCAGATGGACACATTAAAGACCAAAGGCTGGATGGAAGAACAGAATCATGGAGTCAGA
ACAACCCATTTGGTTCCCAAACAGTATAGAGTTGTTGAAACAAGAGGACCTCTCTGTTCAGTGA
GAAGTGAAAAGAGGTATTCAAAAGGAAAAGCTGACACAGAGAAGGTGGTGGGACTCCGATTTGA
AAAGGACGGTACAAGAGGACACCAGTTGGAGCCTGATCTGTCAGAAGAAGTGTCTGCCCGGCTT
CGCCTGGGAAGTGGAAGCAATGGCCTACTCAGAAGGAAAATATCAGTGCTTGAGGCAAAGGAAA
AGAACTTCCCAAGCAAAGAGAAGGACAGAAGAACAGAAGATCTCTTTGAACTTACAGAGCATCG
TCTAATTCAGGACATGGAAAAGGAAATCAGTAATGCCCTGGGCCATGGTCCTCCAGATGAGATT
TTGAGCAGCGCTTTCAAGTTACGAATCACCCGTGGAGATATCCAGACCTTAAAGAACTATCACT
GGCTCAATGATGAGGTCATTAATTTTTATATGAATCTTTTAGTGGAGAGGAGTAAAAAGCAAGG
CTACCCAGCACTTCATGCACTCAGTACATTCTTCTATCCTAAATTAAAGTCTGGAGGTTACCAA
GCAGTGAAAAGATGGACCAAAGGGGTGAATCTCTTCGATCAAGAACTTGTTCTGGTTCCTATTC
ATCGGAAGGTACATTGGAGCCTGGTGGTGATGGACCTAAGAAAAAAGTGTCTTAAATATCTGGA
TTCTATGGGACAAAAAGGCCACAGGATCTGTGAGATTCTTCTTCAGTATTTACAGGACGAAAGC
AAGACCAAAAGAAATACAGATCTCAATCTCTTAGAGTGGACCCACTACAGCATGAAGCCACATG
AGATTCCTCAACAGTTGAATGGGAGTGATTGTGGAATGTTTACTTGTAAATACGCAGATTATAT
TTCTAGGGACAAACCTATCACATTCACTCAGCACCAGATGCCTCTCTTCCGGAAGAAGATGGTG
TGGGAAATCCTTCACCAGCAGTTGCTGTGACAATGCCCCGCCTGGTCTTCTAGTTGCTGGTGGT
TCTTTCATGGATGTTTCCATATACCTCATGCATTGTGGGTTGAAAAGTCCCCATCATTTCTCTT
CTCTCACAGGTACTGAGCTCTCCAGAGTGCATGGAGGCCTCTCTACAGTGGCCCTGACGAGAGG
TGTGGAGGGGCTGCTTGCAGCCCTGTTTGTAAGGCTGTGCCTGCTCAGAGCCCTGGACTGTTCG
CCCCATACAAGGACACATACTAATTAATGTTTTGTTTTAAGGCGTTATTTCCATATGAATGTGG
GAAATGCAGGATTTGTTATATGAATTGTTCTCTGTGTGTTCACACATATTCACTCACTCATTTG
CAAACACTGGGCAGTGCCCTTTCCCACTGCTCTTTTATAATTAGCTATAAATAATTTGTTTGGA
CTATTTATTTCTGAAAAGAATGTTAATCAAACTGCCACTCCCTGCTGCAGAGATGTCCGCAGGG
GGAGGGAGGTGTTCGCCAGCTTCTCTAGTGCCGGGAACTGAACGCACAGTTAAGGTTCTCGTTT
AAGGCTTGGAAATGCCAGAAGAAATGATGATGCTCTGTTGTAGGGGTCTGGCTGCCTTTAGAGA
GCCTGATGCTATGACACGGGCACAGTTCATGGAAAGTGGCCAAGGAACGTGGTCCGTGAGTCCT
CACAGCAGGGCACACTCATCTTCAAGACTTTCTTCTCTAGAACTGAAGTAGCTTGGCTTCCTCA
TGAAACTGGATTCAAAGTAACTGTGACCATAAATGTCAAACCCGAGGTTGGTGAGCCTGCGCTC
ACAGTGGTAAGGGCTGGCCTGAGCTGTATTTCAGGAGATGCTCCTCAATTTAAGCCTATTTTTC
CTCAGAGTTTTTTTAAATATATATGAAGCTGAATTAAGTCTGGCTCAGCAGCATGCTCTACTCC
AGCCCCACTGAGCCTTCGCAGAGATTCGTGCTCGGCTCTGAGGTTGCCGGGTTTACAGTCATCT
ATTTTGCATATGAAAGTTTGTATTTAACTCTTTTGTTCATTAAAAATCTTACAGATGTGGTTAT
GCATTTTTAATTTCAGAAAGTTGGTCAGAGCATATTTTGCAAGATCTAGTGCCTAGTGTTGCTT
TTATGATGTAATAAAAGACTGTCTGGCAGAACCTAGCAGTATGTTGATAATTTTTCCTCTTTTC
TCTGCTTCAACCTTCCAAACTTGTTCTGGTTAAAAAAATAAAAATTAGAAAAGCTGCTCACATG
TTAGATACAAATGGACACATCTGCTCTCTCTCGGAAAGTCCGGGCAGCTGATCAGAGGTGGTAG
CTGTTGAAACCTGTTTTAACCTGTTTTCCGTGAGACTTGAAGTGGCCTTGGTCATGGTAGCTGG
GCTGTGATATTGACCGAAGTGGCTGAGCCTACCACCCAGACCAGGTTAGCCAGACATTCAGAGG
AAACCATGCTGTCTCCTCCAAGCAGACTACACGGGGACCCCTTCCTTTAGCCTAGACCCCCTAG
GAACTGTGCCACTGATGCTGCCCAGATCAGGCAGCTGGTCTAGCCAGAGAGCCCAGAAGTTGAC
CATGTCTACACTACTGAAAACTGGGAGCTAGAATTCTGCCTGAGAATTTCTGACCCAGGCCTAT
GGAAAGCAGTGTGACCTGAGTGTGACTCCCTAGTACCACACTGGAAGGTGAAAACGACTCCCTA
CACTGTCCTCAGACTCCGTACTTGCACACACCAACAGATGGACCAAAGAGTAATAAGCAAGTGC
ACTTTAAAGGAATTTTAAGGGCTTGGATAGGTTTGTTTCTGTTGGCTCAGTCCTGCTTAGATGG
CCCAGGTGAGATTCTGTAGCTAATGTGGCGGCTGATGGATATCCTCAAGCTTGCCCTGTGTGTG
CTCTTGACAGGTGTTCTTAAGCTTCAGAAAGGAAGATGGAGAGATGGTTCAGTGGTGAGGCCAG
AATTGACTTTTAGTCTCAGGCCAGCACATCCATAGCAAACAAGCTGGGCTCCTGCTCACAACGA
TAGTCCCAGTTCCCAGCGAAGAGAGGCAGGGTGATTAGACCCTTCCTCAGGATCAGGAGGAATG
ACAGGACAACCTCGCCTCCCTCGGCCTCGCTCATCCGCTTCAGGTGCATACGCCGCGAGACTTT
TACAGAACACGGTAAAACACGCACGTAGAGAACGTTAAACTACGACGCACTGCTTTACCTCAGT
TTGTGACTCCAAGCTCAGATGCCGGAAGCCATGGCTCTCAAGGCACTGATGTCTCTCTCTGTAC
AAACAAGTGTGTGGGTAACAGAATTGTTACATTCAGCTTGTGAGAAGAGTAAATAAGTGATAAA
CAGCCCTTGGTGTAACTAGTGAGTCAGCAAAATTAAAGCAAGTAACGTTTTTTGTGGAATTTCA
ACTTTGGAACCTGAAAGAAATGTTGCATTGTTCTGTTTAGCCCATAGTCTCTCTAAAAATGAGT
AAAAATTTAAGAAACACA

hide sequence

RefSeq Acc Id:

XM_039088632 ⟹ XP_038944560

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	78,981,429 - 79,017,969 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_076479	(Get FASTA)	NCBI Sequence Viewer
	XP_008767027	(Get FASTA)	NCBI Sequence Viewer
	XP_038944560	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAG34653	(Get FASTA)	NCBI Sequence Viewer
	EDL78045	(Get FASTA)	NCBI Sequence Viewer
	EDL78046	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002425
	ENSRNOP00000002425.4
	ENSRNOP00000071258
	ENSRNOP00000071258.2
	ENSRNOP00000081876.1
	ENSRNOP00000091248.1
GenBank Protein	Q9EQE1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_076479 ⟸ NM_023989

- UniProtKB:

Q9EQE1 (UniProtKB/Swiss-Prot), A6JS62 (UniProtKB/TrEMBL), A0A0G2K009 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYRWLTKVLGTILRLCERPAPGARALLKRRRSSSSLFSTAVDTDEIPAKRPRLDCFIHQVKNSL
YNAASLFGFPFQLTTKPMVSSACNGTRNVAPSGEVFSNSPSCELTTSGSCSSMLKLGNKSPNGI
SDYPKIRVTVARDQPRRVLPSFGFTLKSEGYNRRPSGRRHSKSNPESSLPWKPQEQGVTEMISE
EGGKGARRPHCTVEEGVQKDEREKYLKLLERLKEGAHGSTFPPAVSHHSSQRTQMDTLKTKGWM
EEQNHGVRTTHLVPKQYRVVETRGPLCSVRSEKRYSKGKADTEKVVGLRFEKDGTRGHQLEPDL
SEEVSARLRLGSGSNGLLRRKISVLEAKEKNFPSKEKDRRTEDLFELTEDMEKEISNALGHGPP
DEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERSKKQGYPALHALSTFFYPKLKSG
GYQAVKRWTKGVNLFDQELVLVPIHRKVHWSLVVMDLRKKCLKYLDSMGQKGHRICEILLQYLQ
DESKTKRNTDLNLLEWTHYSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRK
KMVWEILHQQLL

hide sequence

RefSeq Acc Id:	XP_008767027 ⟸ XM_008768805
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2PZM6 (UniProtKB/TrEMBL), A0A0G2K009 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYRWLTKVLGTILRLCERPAPGARALLKRRRSSSSLFSTAVDTDEIPAKRPRLDCFIHQVKNSL YNAASLFGFPFQLTTKPMVSSACNGTRNVAPSGEVFSNSPSCELTTSGSCSSMLKLGNKSPNGI SDYPKIRVTVARDQPRRVLPSFGFTLKSEGYNRRPSGRRHSKSNPESSLPWKPQEQGVTEMISE EGGKGARRPHCTVEEGVQKDEREKYLKLLERLKEGAHGSTFPPAVSHHSSQRTQMDTLKTKGWM EEQNHGVRTTHLVPKQYRVVETRGPLCSVRSEKRYSKGKADTEKVVGLRFEKDGTRGHQLEPDL SEEVSARLRLGSGSNGLLRRKISVLEAKEKNFPSKEKDRRTEDLFELTEHRLIQDMEKEISNAL GHGPPDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERSKKQGYPALHALSTFFYP KLKSGGYQAVKRWTKGVNLFDQELVLVPIHRKVHWSLVVMDLRKKCLKYLDSMGQKGHRICEIL LQYLQDESKTKRNTDLNLLEWTHYSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQM PLFRKKMVWEILHQQLL hide sequence

RefSeq Acc Id:

ENSRNOP00000002425 ⟸ ENSRNOT00000002425

RefSeq Acc Id:

ENSRNOP00000071258 ⟸ ENSRNOT00000087105

RefSeq Acc Id:	XP_038944560 ⟸ XM_039088632
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2K009 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000081876 ⟸ ENSRNOT00000098721

RefSeq Acc Id:

ENSRNOP00000091248 ⟸ ENSRNOT00000112722

Protein Domains

Ubiquitin-like protease family profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9EQE1-F1-model_v2	AlphaFold	Q9EQE1	1-588	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698262

Promoter ID:

EPDNEW_R8784

Type:

multiple initiation site

Name:

Senp2_1

Description:

Sumo1/sentrin/SMT3 specific peptidase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	82,664,631 - 82,664,691	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708378	AgrOrtholog
BioCyc Gene	G2FUF-20795	BioCyc
Ensembl Genes	ENSRNOG00000001773	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002425	ENTREZGENE
	ENSRNOT00000002425.7	UniProtKB/TrEMBL
	ENSRNOT00000087105	ENTREZGENE
	ENSRNOT00000087105.2	UniProtKB/TrEMBL
	ENSRNOT00000098721.1	UniProtKB/TrEMBL
	ENSRNOT00000112722.1	UniProtKB/TrEMBL
InterPro	Papain-like_cys_pep_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Peptidase_C48_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:78973	UniProtKB/Swiss-Prot
NCBI Gene	78973	ENTREZGENE
PANTHER	SENTRIN-SPECIFIC PROTEASE 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SENTRIN/SUMO-SPECIFIC PROTEASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Peptidase_C48	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Senp2	PhenoGen
PROSITE	ULP_PROTEASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000001773	RatGTEx
Superfamily-SCOP	SSF54001	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2K009	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZTE8_RAT	UniProtKB/TrEMBL
	A0A8I6AFS4_RAT	UniProtKB/TrEMBL
	A0A8L2PZM6	ENTREZGENE, UniProtKB/TrEMBL
	A6JS62	ENTREZGENE, UniProtKB/TrEMBL
	Q9EQE1	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-03-01	Senp2	SUMO specific peptidase 2	Senp2	Sumo1/sentrin/SMT3 specific peptidase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-12-15	Senp2	Sumo1/sentrin/SMT3 specific peptidase 2	Senp2	SUMO1/sentrin/SMT3 specific peptidase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-20	Senp2	SUMO1/sentrin/SMT3 specific peptidase 2	Senp2	SUMO/sentrin specific peptidase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Senp2	SUMO/sentrin specific peptidase 2	Senp2	SUMO/sentrin specific protease 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-12-14	Senp2	SUMO/sentrin specific protease 2	LOC78973	Axin-associating molecule	Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)