Mir877 (microRNA 877) - Rat Genome Database

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Gene: Mir877 (microRNA 877) Rattus norvegicus
Analyze
Symbol: Mir877
Name: microRNA 877
RGD ID: 2325510
Description: Predicted to enable mRNA base-pairing translational repressor activity. Predicted to be involved in miRNA-mediated gene silencing by inhibition of translation. Predicted to act upstream of or within cellular senescence. Orthologous to human MIR877 (microRNA 877); INTERACTS WITH 2,5-hexanedione; methapyrilene; nitrofen.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-877
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2202,811,476 - 2,811,560 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl202,811,476 - 2,811,560 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx202,863,052 - 2,863,136 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0202,868,021 - 2,868,105 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0202,894,453 - 2,894,537 (+)NCBIRnor_WKY
Rnor_6.0203,318,872 - 3,318,956 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,318,872 - 3,318,956 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,416,400 - 5,416,484 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera20237,323 - 237,407 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:17604727   PMID:17964270   PMID:20403161   PMID:25751060   PMID:26718435   PMID:34331398  


Genomics

Comparative Map Data
Mir877
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2202,811,476 - 2,811,560 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl202,811,476 - 2,811,560 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx202,863,052 - 2,863,136 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0202,868,021 - 2,868,105 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0202,894,453 - 2,894,537 (+)NCBIRnor_WKY
Rnor_6.0203,318,872 - 3,318,956 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,318,872 - 3,318,956 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,416,400 - 5,416,484 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera20237,323 - 237,407 (+)NCBICelera
Cytogenetic Map20p12NCBI
MIR877
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,584,332 - 30,584,417 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl630,584,332 - 30,584,417 (+)EnsemblGRCh38hg38GRCh38
GRCh37630,552,109 - 30,552,194 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,660,087 - 30,660,172 (+)NCBINCBI36Build 36hg18NCBI36
Celera632,150,226 - 32,150,311 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef630,352,183 - 30,352,268 (+)NCBIHuRef
CHM1_1630,554,223 - 30,554,308 (+)NCBICHM1_1
T2T-CHM13v2.0630,448,515 - 30,448,600 (+)NCBIT2T-CHM13v2.0
Mir877
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,271,622 - 36,271,706 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,271,622 - 36,271,706 (-)EnsemblGRCm39 Ensembl
GRCm381735,960,730 - 35,960,814 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,960,730 - 35,960,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv371736,097,675 - 36,097,759 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1739,474,255 - 39,474,339 (-)NCBICelera
Cytogenetic Map17B1NCBI

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:14389
Count of gene targets:7197
Count of transcripts:7722
Interacting mature miRNAs:rno-miR-877
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat

Markers in Region
RH140082  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,810,160 - 2,810,370 (+)MAPPERmRatBN7.2
Rnor_6.0203,317,557 - 3,317,766NCBIRnor6.0
Rnor_5.0205,415,085 - 5,415,294UniSTSRnor5.0
RGSC_v3.4202,956,869 - 2,957,078UniSTSRGSC3.4
Celera20236,008 - 236,217UniSTS
Cytogenetic Map20p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 10 14 3 3 6 5 3 6 3
Below cutoff 3 1 1 2 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_032258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000062976
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,811,476 - 2,811,560 (+)Ensembl
Rnor_6.0 Ensembl203,318,872 - 3,318,956 (+)Ensembl
RefSeq Acc Id: NR_032258
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2202,811,476 - 2,811,560 (+)NCBI
Rnor_6.0203,318,872 - 3,318,956 (+)NCBI
Rnor_5.0205,416,400 - 5,416,484 (+)NCBI
Celera20237,323 - 237,407 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325510 AgrOrtholog
BioCyc Gene G2FUF-4788 BioCyc
Ensembl Genes ENSRNOG00000041223 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000062976 ENTREZGENE
miRBase MI0006119 ENTREZGENE
NCBI Gene 100314097 ENTREZGENE
PhenoGen Mir877 PhenoGen
RNAcentral URS00005240FD RNACentral
  URS000064C80E RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir877  microRNA 877  Mir877  microRNA mir-877  Name updated 61478 APPROVED
2010-06-02 Mir877  microRNA mir-877      Symbol and Name status set to provisional 70820 PROVISIONAL