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G |
A1bg |
alpha-1-B glycoprotein |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of A1BG mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of A1BG mRNA] |
CTD |
PMID:22129741 |
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NCBI chr15:60,789,438...60,793,119
Ensembl chr15:60,768,708...60,794,861
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G |
Abca1 |
ATP-binding cassette, sub-family A member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased methylation of ABCA1 promoter] |
CTD |
PMID:31150806 |
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NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
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G |
Abca5 |
ATP-binding cassette, sub-family A member 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA5 mRNA] |
CTD |
PMID:31004932 |
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NCBI chr11:110,160,195...110,228,542
Ensembl chr11:110,160,195...110,228,542
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G |
Abcb1a |
ATP-binding cassette, sub-family B member 1A |
multiple interactions |
ISO |
Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]; Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] |
CTD |
PMID:10636889 PMID:18474546 PMID:22914566 PMID:23867903 PMID:25824409 |
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NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
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G |
Abcc1 |
ATP-binding cassette, sub-family C member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC1 mRNA]; Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC1 protein]; Acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]; Buthionine Sulfoximine analog inhibits the reaction [Acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]] |
CTD |
PMID:11820781 PMID:15473893 PMID:22914566 PMID:23867903 |
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NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
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G |
Abcc2 |
ATP-binding cassette, sub-family member 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA] Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCC2 protein] |
CTD |
PMID:22914566 PMID:23867903 PMID:34303734 |
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NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
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G |
Abcc3 |
ATP-binding cassette, sub-family C member 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC3 protein] |
CTD |
PMID:11820781 |
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NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of ABCG1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
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G |
Abcg4 |
ATP binding cassette subfamily G member 4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ABCG4 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCG4 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 9:44,184,485...44,199,953
Ensembl chr 9:44,184,485...44,199,912
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G |
Abl1 |
c-abl oncogene 1, non-receptor tyrosine kinase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [NSC 680410 results in decreased phosphorylation of ABL1 protein] |
CTD |
PMID:16481037 |
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NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239
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G |
Ache |
acetylcholinesterase |
multiple interactions affects response to substance |
ISO EXP |
[Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Cadmium results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Dimethoate results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of ACHE protein] Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of ACHE mRNA alternative form]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein] ACHE protein affects the susceptibility to Acetylcysteine |
CTD |
PMID:20399762 PMID:20688495 PMID:26769589 PMID:27087133 PMID:27163631 PMID:28499986 PMID:29253600 PMID:30639957 PMID:31173782 PMID:34425170 More...
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NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
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G |
Acp3 |
acid phosphatase 3 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACP3 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 9:104,165,439...104,214,921
Ensembl chr 9:104,165,450...104,214,947
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G |
Acsm5 |
acyl-CoA synthetase medium-chain family member 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACSM5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACSM5 mRNA] |
CTD |
PMID:22129741 |
|
NCBI chr 7:119,125,354...119,142,583
Ensembl chr 7:119,118,686...119,144,774
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G |
Acss1 |
acyl-CoA synthetase short-chain family member 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACSS1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:150,460,031...150,510,160
Ensembl chr 2:150,460,025...150,510,420
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G |
Acta2 |
actin alpha 2, smooth muscle, aorta |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ACTA2 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ACTA2 mRNA] |
CTD |
PMID:16757516 PMID:21134390 PMID:32659284 PMID:33131013 PMID:35622622 PMID:36493885 PMID:38488660 More...
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NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
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G |
Adam17 |
a disintegrin and metallopeptidase domain 17 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [necrostatin-1 results in increased expression of ADAM17 mRNA]; Acetylcysteine inhibits the reaction [necrostatin-1 results in increased expression of ADAM17 protein] |
CTD |
PMID:37422542 |
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NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
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G |
Adam33 |
a disintegrin and metallopeptidase domain 33 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ADAM33 mRNA] |
CTD |
PMID:29753051 |
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NCBI chr 2:130,892,739...130,905,734
Ensembl chr 2:130,892,511...130,905,734
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G |
Adgrb2 |
adhesion G protein-coupled receptor B2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:129,878,566...129,916,426
Ensembl chr 4:129,878,663...129,916,426
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G |
Adgrb3 |
adhesion G protein-coupled receptor B3 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB3 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 1:25,106,557...25,869,338
Ensembl chr 1:25,106,557...25,868,788
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G |
Adh1 |
alcohol dehydrogenase 1 (class I) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Ethanol results in increased expression of ADH1 mRNA] |
CTD |
PMID:20705415 |
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NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Palmitates results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in decreased expression of ADIPOQ protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]] |
CTD |
PMID:17471172 PMID:21912612 |
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NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
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G |
Adipor2 |
adiponectin receptor 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] |
CTD |
PMID:21912612 |
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NCBI chr 6:119,330,111...119,394,489
Ensembl chr 6:119,330,111...119,394,665
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] Acetylcysteine inhibits the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species] |
CTD |
PMID:15849355 PMID:30703374 |
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NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
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G |
Agtr1a |
angiotensin II receptor, type 1a |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of AGTR1 mRNA] |
CTD |
PMID:23603059 |
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NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
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G |
Ahr |
aryl-hydrocarbon receptor |
increases expression multiple interactions |
EXP ISO |
Acetylcysteine results in increased expression of AHR protein Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of and affects the localization of AHR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of AHR protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1A enhancer]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1B enhancer] |
CTD |
PMID:18022818 PMID:21569840 PMID:31551408 PMID:35123993 |
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NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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G |
Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of AIF1 protein]] |
CTD |
PMID:36762617 |
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NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044
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G |
Aifm1 |
apoptosis-inducing factor, mitochondrion-associated 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride affects the localization of AIFM1 protein] Acetylcysteine inhibits the reaction [1,12-benzoperylene results in increased expression of AIFM1 protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone affects the localization of AIFM1 protein] Acetylcysteine inhibits the reaction [bisphenol A affects the localization of AIFM1 protein] |
CTD |
PMID:18034189 PMID:18412143 PMID:18506790 PMID:18951928 PMID:19679660 PMID:21741372 PMID:27189055 PMID:31518672 More...
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NCBI chr X:47,563,821...47,602,440
Ensembl chr X:47,563,821...47,602,440
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G |
Aim2 |
absent in melanoma 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of AIM2 mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of AIM2 protein] |
CTD |
PMID:39362619 |
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NCBI chr 1:173,177,105...173,293,606
Ensembl chr 1:173,178,445...173,293,606
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G |
Aimp1 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of AIMP1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 3:132,366,259...132,390,151
Ensembl chr 3:132,366,242...132,390,131
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G |
Akr1c18 |
aldo-keto reductase family 1, member C18 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AKR1C3 mRNA] |
CTD |
PMID:18829485 PMID:21787718 |
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NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
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G |
Akt1 |
thymoma viral proto-oncogene 1 |
multiple interactions |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased activity of and results in increased phosphorylation of AKT1 protein]; [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of and affects the localization of AKT1 protein]; Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [butein results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E affects the phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cyadox results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Daunorubicin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [divinyl sulfone analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Morpholines analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [morusin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [N-arachidonoylalanine results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [oenothein B results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Oligopeptides analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Patulin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [synaptamide results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [tubocapsenolide A results in increased degradation of AKT1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of AKT1 protein]; Acetylcysteine results in increased activity of and results in increased phosphorylation of AKT1 protein Acetylcysteine inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of AKT1 mRNA] Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Zinc results in increased phosphorylation of AKT1 protein] N-acetyl=L-cysteine inhibits the reaction [ethanol decreases phosphorylation of Akt1 protein in the liver] |
CTD RGD |
PMID:12168106 PMID:12614848 PMID:16137721 PMID:16731823 PMID:18442981 PMID:21055460 PMID:21195169 PMID:21787718 PMID:22427991 PMID:22867088 PMID:23000059 PMID:23159718 PMID:23948867 PMID:24299490 PMID:24449419 PMID:24489685 PMID:24582688 PMID:24875536 PMID:24933620 PMID:25199686 PMID:25471227 PMID:25939952 PMID:25944616 PMID:26514923 PMID:26804764 PMID:26942697 PMID:27106530 PMID:27117918 PMID:27411387 PMID:27658547 PMID:28087840 PMID:28600122 PMID:29604266 PMID:30265530 PMID:30452899 PMID:30797898 PMID:30871965 PMID:31068539 PMID:31157476 PMID:32305283 PMID:32745510 PMID:33035517 PMID:34963561 PMID:35130734 PMID:36810933 PMID:37148176 PMID:37751786 PMID:38521250 PMID:28987868 More...
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RGD:407574728 |
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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G |
Akt2 |
thymoma viral proto-oncogene 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of AKT2 protein] |
CTD |
PMID:37751786 |
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NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
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G |
Akt3 |
thymoma viral proto-oncogene 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of AKT3 protein] |
CTD |
PMID:37751786 |
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NCBI chr 1:176,847,642...177,091,688
Ensembl chr 1:176,847,639...177,085,769
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G |
Alad |
aminolevulinate, delta-, dehydratase |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [sodium arsenite results in decreased activity of ALAD protein]] |
CTD |
PMID:16959597 |
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NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
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G |
Alb |
albumin |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Acetylcysteine inhibits the reaction [ALB protein modified form results in decreased expression of MFN2 protein]; Acetylcysteine inhibits the reaction [ALB protein modified form results in increased abundance of Hydrogen Peroxide]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]; Acetylcysteine inhibits the reaction [Mustard Gas results in increased expression of ALB protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]] |
CTD |
PMID:11428623 PMID:20804811 PMID:24485406 PMID:27997345 |
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NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
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G |
Aldh2 |
aldehyde dehydrogenase 2, mitochondrial |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Nitroglycerin results in decreased activity of ALDH2 protein] |
CTD |
PMID:17585900 |
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NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
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G |
Alk |
anaplastic lymphoma kinase |
multiple interactions |
ISO |
Acetylcysteine affects the phosphorylation of and affects the activity of ALK protein mutant form |
CTD |
PMID:19503098 |
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NCBI chr17:72,174,206...72,911,719
Ensembl chr17:72,175,967...72,911,622
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G |
Alkbh5 |
alkB homolog 5, RNA demethylase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ALKBH5 mRNA] Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of ALKBH5 mRNA] |
CTD |
PMID:31004932 PMID:34425375 |
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NCBI chr11:60,428,509...60,449,338
Ensembl chr11:60,427,207...60,449,338
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G |
Alpl |
alkaline phosphatase, liver/bone/kidney |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of ALPL mRNA] |
CTD |
PMID:34547296 |
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NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
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G |
Amacr |
alpha-methylacyl-CoA racemase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AMACR mRNA] |
CTD |
PMID:18829485 |
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NCBI chr15:10,981,875...10,995,693
Ensembl chr15:10,981,842...10,996,712
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G |
Ang |
angiogenin, ribonuclease, RNase A family, 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of ANG protein] |
CTD |
PMID:26138014 |
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NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466
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G |
Angpt1 |
angiopoietin 1 |
decreases secretion |
ISO |
Acetylcysteine results in decreased secretion of ANGPT1 protein |
CTD |
PMID:19622383 |
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NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ANGPTL4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
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G |
Ankrd29 |
ankyrin repeat domain 29 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ANKRD29 mRNA |
CTD |
PMID:22129741 |
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NCBI chr18:12,385,414...12,439,067
Ensembl chr18:12,385,419...12,438,854
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G |
Anxa5 |
annexin A5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ANXA5 protein]; Acetylcysteine inhibits the reaction [Tin Fluorides results in increased expression of ANXA5 protein] |
CTD |
PMID:22093110 |
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NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
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G |
Aoc1 |
amine oxidase, copper-containing 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Methotrexate results in increased activity of AOC1 protein] |
CTD |
PMID:20885979 |
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NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of APAF1 mRNA]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of APAF1 protein] Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of APAF1 protein] |
CTD |
PMID:15877105 PMID:19477266 PMID:35396826 |
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NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
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G |
Apex1 |
apurinic/apyrimidinic endonuclease 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of APEX1 protein] Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of APEX1 mRNA] |
CTD |
PMID:12231548 PMID:17938202 |
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NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596
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G |
Apex2 |
apurinic/apyrimidinic endonuclease 2 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of APEX2 mRNA] Acetylcysteine results in decreased expression of APEX2 mRNA |
CTD |
PMID:26332274 |
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NCBI chr X:149,286,625...149,371,175
Ensembl chr X:149,302,515...149,372,864
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G |
Aph1b |
aph1 homolog B, gamma secretase subunit |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of APH1B mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:66,682,484...66,704,671
Ensembl chr 9:66,682,484...66,702,772
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G |
Apoe |
apolipoprotein E |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of APOE mRNA Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of APOE mRNA] |
CTD |
PMID:33188856 |
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NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [APP protein affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of NLRP3 protein] |
CTD |
PMID:12684028 PMID:28004443 |
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NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
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G |
Aqp2 |
aquaporin 2 |
increases expression |
ISO |
Acetylcysteine results in increased expression of AQP2 protein |
CTD |
PMID:23183129 |
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NCBI chr15:99,476,937...99,482,426
Ensembl chr15:99,476,936...99,482,428
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the activity of AR protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR mRNA]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR protein] |
CTD |
PMID:16928829 PMID:18829485 |
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NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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G |
Arl13a |
ADP-ribosylation factor-like 13A |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ARL13A mRNA |
CTD |
PMID:22129741 |
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NCBI chr X:133,088,250...133,108,779
Ensembl chr X:133,088,250...133,108,777
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Curcumin results in increased degradation of ARNT protein] |
CTD |
PMID:16880289 |
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NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
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G |
Arrdc3 |
arrestin domain containing 3 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ARRDC3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr13:81,031,508...81,044,161
Ensembl chr13:81,031,503...81,044,161
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G |
Art4 |
ADP-ribosyltransferase 4 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of ART4 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 6:136,825,449...136,834,598
Ensembl chr 6:136,825,449...136,834,731
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G |
Asns |
asparagine synthetase |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ASNS mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
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G |
Astl |
astacin like metalloendopeptidase |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ASTL mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:127,180,559...127,199,575
Ensembl chr 2:127,180,559...127,199,571
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G |
Atf2 |
activating transcription factor 2 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of ATF2 protein] Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of ATF2 protein] |
CTD |
PMID:19654923 PMID:22288910 |
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NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of and affects the localization of ATF3 protein] |
CTD |
PMID:25531190 |
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NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [bisphenol S results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased expression of ATF4 protein] Acetylcysteine results in increased expression of ATF4 protein Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ATF4 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ATF4 protein]; Acetylcysteine promotes the reaction [perfluorooctanoic acid results in increased expression of ATF4 mRNA] Acetylcysteine results in decreased expression of ATF4 protein [Acetylcysteine co-treated with Trichloroethylene] results in increased expression of ATF4 mRNA; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ATF4 protein] |
CTD |
PMID:15788408 PMID:19722195 PMID:21266191 PMID:24291486 PMID:25451595 PMID:25568320 PMID:27484784 PMID:27634458 PMID:27816613 PMID:28754437 PMID:31330229 PMID:32506763 PMID:32578922 PMID:36396003 PMID:37072049 PMID:37300854 PMID:37944787 More...
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NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in increased expression of ATF6 protein]; Acetylcysteine results in increased metabolism of and results in increased activity of ATF6 protein Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of ATF6 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased cleavage of ATF6 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ATF6 protein] Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF6 protein modified form]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ATF6 protein] |
CTD |
PMID:18077580 PMID:19722195 PMID:21198628 PMID:21911445 PMID:24291486 PMID:25451595 PMID:31330229 PMID:34520753 PMID:37148176 PMID:37692514 More...
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NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
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G |
Atg10 |
autophagy related 10 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG10 mRNA] |
CTD |
PMID:24614525 |
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NCBI chr13:91,083,467...91,372,189
Ensembl chr13:91,083,475...91,372,087
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G |
Atg12 |
autophagy related 12 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG12 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [Vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]] Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG12 mRNA] |
CTD |
PMID:20543569 PMID:24614525 PMID:29307831 PMID:30205151 PMID:33146789 PMID:34439521 More...
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NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647
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G |
Atg14 |
autophagy related 14 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATG14 mRNA] |
CTD |
PMID:34439521 |
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NCBI chr14:47,778,350...47,805,891
Ensembl chr14:47,778,350...47,808,106
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G |
Atg16l1 |
autophagy related 16 like 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG16L1 protein] |
CTD |
PMID:30205151 |
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NCBI chr 1:87,683,730...87,720,150
Ensembl chr 1:87,683,592...87,720,150
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G |
Atg16l2 |
autophagy related 16 like 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG16L2 mRNA] |
CTD |
PMID:33146789 |
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NCBI chr 7:100,935,521...100,951,474
Ensembl chr 7:100,912,241...100,951,458
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G |
Atg4a |
autophagy related 4A, cysteine peptidase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ATG4A protein] |
CTD |
PMID:29179951 |
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NCBI chr X:139,854,594...139,947,190
Ensembl chr X:139,857,656...139,947,266
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G |
Atg4c |
autophagy related 4C, cysteine peptidase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of ATG4C mRNA] |
CTD |
PMID:34425375 |
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NCBI chr 4:99,077,181...99,185,495
Ensembl chr 4:99,082,171...99,148,024
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of ATG5 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG5 mRNA] |
CTD |
PMID:20543569 PMID:24614525 PMID:28600122 PMID:29307831 PMID:30205151 PMID:33146789 PMID:33462182 More...
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NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATG7 mRNA]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG7 protein]; Acetylcysteine inhibits the reaction [Apigenin results in increased expression of ATG7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG7 mRNA] |
CTD |
PMID:29247770 PMID:29307831 PMID:30205151 PMID:31319114 PMID:33462182 |
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NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575
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G |
Atm |
ataxia telangiectasia mutated |
multiple interactions increases phosphorylation |
ISO EXP |
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ATM protein]; Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of ATM protein modified form]; Acetylcysteine inhibits the reaction [ATM protein promotes the reaction [Doxorubicin results in increased activity of TP53 protein]]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK1 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of NBN protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of SMC1A protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [polyhexamethyleneguanidine results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased phosphorylation of ATM protein] Acetylcysteine results in increased phosphorylation of ATM protein Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of ATM protein] Acetylcysteine affects the reaction [yttrium chloride affects the expression of ATM protein] |
CTD |
PMID:15489221 PMID:23274516 PMID:24792323 PMID:26451628 PMID:31168028 PMID:31715134 PMID:32142722 PMID:35088107 More...
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NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
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G |
Atox1 |
antioxidant 1 copper chaperone |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATOX1 mRNA] |
CTD |
PMID:36315628 |
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NCBI chr11:55,337,463...55,352,034
Ensembl chr11:55,337,467...55,352,065
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G |
Atp1a1 |
ATPase, Na+/K+ transporting, alpha 1 polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of ATP1A1 protein] |
CTD |
PMID:10506578 |
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NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
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G |
Atp2a2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
increases expression multiple interactions |
ISO EXP |
Acetylcysteine results in increased expression of ATP2A2 mRNA Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of ATP2A2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP2A2 protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATP2A2 mRNA] |
CTD |
PMID:10625299 PMID:16084531 PMID:17005195 PMID:36315628 |
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NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
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G |
Atp5f1a |
ATP synthase F1 subunit alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of ATP5F1A mRNA] |
CTD |
PMID:36493885 |
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NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569
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G |
Atp6v0d1 |
ATPase, H+ transporting, lysosomal V0 subunit D1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATP6V0D1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATP6V0D1 mRNA] |
CTD |
PMID:29307831 PMID:31319114 |
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NCBI chr 8:106,251,093...106,292,696
Ensembl chr 8:106,251,097...106,292,679
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G |
Atp6v0d2 |
ATPase, H+ transporting, lysosomal V0 subunit D2 |
multiple interactions |
ISO EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ATP6V0D2 mRNA [Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of ATP6V0D2 mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA] |
CTD |
PMID:22129741 PMID:30742845 |
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NCBI chr 4:19,876,838...19,922,566
Ensembl chr 4:19,876,841...19,922,605
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G |
Atr |
ataxia telangiectasia and Rad3 related |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ATR protein] |
CTD |
PMID:26451628 |
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NCBI chr 9:95,739,655...95,834,813
Ensembl chr 9:95,739,650...95,833,834
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G |
Atxn1 |
ataxin 1 |
affects localization multiple interactions |
ISO |
Acetylcysteine affects the localization of ATXN1 protein mutant form Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of ATXN1 protein mutant form]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ATXN1 protein mutant form] |
CTD |
PMID:12893416 |
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NCBI chr13:45,703,231...46,118,467
Ensembl chr13:45,703,231...46,118,484
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G |
Aurkb |
aurora kinase B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of AURKB protein] |
CTD |
PMID:28343997 |
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NCBI chr11:68,936,477...68,942,490
Ensembl chr11:68,936,473...68,942,490
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G |
B2m |
beta-2 microglobulin |
decreases response to substance multiple interactions |
ISO |
Acetylcysteine results in decreased susceptibility to B2M protein modified form Acetylcysteine inhibits the reaction [B2M protein modified form results in increased abundance of Reactive Oxygen Species] |
CTD |
PMID:21864514 |
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NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
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G |
B3galt5 |
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of B3GALT5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr16:96,037,001...96,121,059
Ensembl chr16:96,037,001...96,121,059
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G |
B3gnt9 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of B3GNT9 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:105,979,270...105,981,895
Ensembl chr 8:105,979,270...105,981,785
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G |
Bach1 |
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [alpha-pyrrolidinononanophenone analog results in increased expression of BACH1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of BACH1 protein] |
CTD |
PMID:19350554 PMID:38040126 |
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NCBI chr16:87,495,842...87,530,234
Ensembl chr16:87,495,833...87,530,234
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [cordycepin results in increased expression of BAD protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BAD protein] Acetylcysteine results in increased expression of BAD mRNA |
CTD |
PMID:21310227 PMID:22245127 PMID:26332274 |
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NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
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G |
Bag3 |
BCL2-associated athanogene 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of BAG3 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 protein] Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of BAK1 mRNA] Acetylcysteine inhibits the reaction [Cadmium results in increased expression of BAK1] |
CTD |
PMID:21533816 PMID:21549813 PMID:22085843 PMID:23339468 PMID:28296042 |
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NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
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G |
Barx2 |
BarH-like homeobox 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BARX2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:31,757,340...31,824,581
Ensembl chr 9:31,757,340...31,824,758
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G |
Bax |
BCL2-associated X protein |
multiple interactions increases expression decreases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased activity of BAX protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [dibromoacetonitrile results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased expression of BAX protein]] Acetylcysteine results in increased expression of BAX protein 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Buthionine Sulfoximine] results in decreased expression of BAX protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased localization of BAX protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BAX protein]; Acetylcysteine inhibits the reaction [chromium tripicolinate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of and results in increased activity of BAX protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenbendazole analog results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenbendazole results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [gingerol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [glabridin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [perfosfamide affects the folding of BAX protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of BAX]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Propofol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of BAX protein]]; Acetylcysteine inhibits the reaction [surfactin peptide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester) affects the expression of BAX protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased expression of BAX protein] Acetylcysteine results in decreased expression of BAX protein Acetylcysteine results in increased expression of BAX mRNA Acetylcysteine affects the reaction [lead acetate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [4-nonylphenol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of BAX mRNA] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases expression of BAX protein in the stomach) |
CTD RGD |
PMID:11166918 PMID:11341981 PMID:15496615 PMID:15735709 PMID:16169029 PMID:17237268 PMID:17542780 PMID:17574045 PMID:18034189 PMID:18412143 PMID:18547707 PMID:19376147 PMID:19954742 PMID:20674558 PMID:20981856 PMID:21310227 PMID:21533816 PMID:21549813 PMID:21616140 PMID:22085843 PMID:22245127 PMID:22704995 PMID:23711929 PMID:24036456 PMID:25034532 PMID:25845326 PMID:26332274 PMID:26512966 PMID:26772155 PMID:26797587 PMID:26804764 PMID:27189055 PMID:27816613 PMID:28804952 PMID:29087013 PMID:29248572 PMID:29945211 PMID:30104959 PMID:30769050 PMID:30797898 PMID:30917517 PMID:31173782 PMID:31313457 PMID:31368586 PMID:32402895 PMID:32527420 PMID:32540572 PMID:33031904 PMID:33485121 PMID:33797725 PMID:33971260 PMID:34547296 PMID:35430258 PMID:35569513 PMID:36029289 PMID:36070022 PMID:37084995 PMID:37148176 PMID:37308051 PMID:38065397 PMID:29408335 More...
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RGD:127284846 |
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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G |
Bbc3 |
BCL2 binding component 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA] Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of BBC3 protein] |
CTD |
PMID:24291486 PMID:32540572 |
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NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130
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G |
Bcas1 |
brain enriched myelin associated protein 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BCAS1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:170,188,911...170,270,292
Ensembl chr 2:170,188,911...170,269,765
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G |
Bche |
butyrylcholinesterase |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein] Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of BCHE protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of BCHE protein] |
CTD |
PMID:27087133 PMID:34425170 |
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NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
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G |
Bcl2 |
B cell leukemia/lymphoma 2 |
decreases expression decreases response to substance multiple interactions |
ISO EXP |
Acetylcysteine results in decreased expression of BCL2 protein BCL2 results in decreased susceptibility to Acetylcysteine Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of BCL2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [dibromoacetonitrile results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in decreased expression of BCL2 protein]] 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]]; [saikosaponin D co-treated with Acetylcysteine] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Buthionine Sulfoximine] results in increased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in decreased expression of BCL2 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of and affects the localization of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; Acetylcysteine inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [glabridin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [indole-3-carbinol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [lactucin results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [lactucin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Propofol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [salvin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [surfactin peptide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester) affects the expression of BCL2 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of BCL2 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of BCL2 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in decreased expression of BCL2 protein] Acetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of BCL2 protein] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases expression of BCL2 protein in the stomach) |
CTD RGD |
PMID:11341981 PMID:17041759 PMID:17395010 PMID:17542780 PMID:18077580 PMID:18412143 PMID:19082730 PMID:19679660 PMID:19954742 PMID:20674558 PMID:21310227 PMID:21549813 PMID:21600978 PMID:21616140 PMID:22085843 PMID:22245127 PMID:22578287 PMID:22704995 PMID:22976841 PMID:23711929 PMID:24036456 PMID:24909818 PMID:25034532 PMID:25845326 PMID:26079211 PMID:26772155 PMID:27816613 PMID:28804952 PMID:28918123 PMID:29248572 PMID:30104959 PMID:30769050 PMID:30796935 PMID:30797898 PMID:30917517 PMID:31157476 PMID:31173782 PMID:31368586 PMID:31563593 PMID:31900833 PMID:32402895 PMID:32527420 PMID:33002460 PMID:33118390 PMID:33485121 PMID:34302634 PMID:34303041 PMID:34547296 PMID:34599545 PMID:36029289 PMID:37084995 PMID:37209937 PMID:37308051 PMID:38065397 PMID:29408335 More...
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RGD:127284846 |
NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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G |
Bcl2l1 |
BCL2-like 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [Carboplatin results in decreased expression of BCL2L1 protein] Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [indole-3-carbinol results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of BCL2L1 protein] Acetylcysteine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2L1 protein] |
CTD |
PMID:18281123 PMID:18483861 PMID:20594983 PMID:21310227 PMID:22085843 PMID:22245127 PMID:23711929 PMID:30917517 PMID:31313457 PMID:31900833 PMID:33118390 PMID:37308051 More...
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NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
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G |
Bcl2l11 |
BCL2 like 11 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased expression of BCL2L11 protein] |
CTD |
PMID:15173094 |
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NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
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G |
Bcl6 |
B cell leukemia/lymphoma 6 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BCL6 mRNA |
CTD |
PMID:22129741 |
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NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
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G |
Bdkrb1 |
bradykinin receptor, beta 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA] |
CTD |
PMID:22264228 |
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NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
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G |
Bdnf |
brain derived neurotrophic factor |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of BDNF protein] Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in decreased phosphorylation of BDNF protein] |
CTD |
PMID:16553631 PMID:26138014 PMID:38642822 |
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NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
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G |
Becn1 |
beclin 1, autophagy related |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [alpha-pyrrolidinononanophenone results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [brazilin results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of and results in increased phosphorylation of BECN1 protein]; Acetylcysteine inhibits the reaction [Deuterium Oxide results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Vorinostat results in increased expression of BECN1 protein] Acetylcysteine inhibits the reaction [[Air Pollutants, Occupational results in increased abundance of Particulate Matter] which results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [[CASP2 protein affects the susceptibility to Rotenone] which results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of BECN1 protein]; Acetylcysteine inhibits the reaction [dibromoacetonitrile results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Trichloroethylene results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of BECN1 protein] Acetylcysteine inhibits the reaction [4-nonylphenol results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of BECN1 protein] |
CTD |
PMID:20543569 PMID:21216964 PMID:24614525 PMID:26588882 PMID:26804764 PMID:27106530 PMID:27208422 PMID:28025121 PMID:28063998 PMID:28578026 PMID:28600122 PMID:29923297 PMID:31563593 PMID:32687844 PMID:33146789 PMID:34439521 PMID:36739042 PMID:36849104 PMID:37751786 PMID:38065397 More...
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NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
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G |
Bglap |
bone gamma carboxyglutamate protein |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BGLAP mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BGLAP protein] |
CTD |
PMID:34547296 |
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NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [sanguinarine results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein] Acetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein] |
CTD |
PMID:16169029 PMID:17574045 PMID:21310227 PMID:23660334 PMID:23711929 PMID:25034532 PMID:25845326 PMID:30408460 More...
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NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
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G |
Bik |
BCL2-interacting killer |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of BIK protein] |
CTD |
PMID:31313457 |
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NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC2 protein] |
CTD |
PMID:19679660 |
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NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC3 protein] |
CTD |
PMID:19679660 |
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NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BIRC5 protein] |
CTD |
PMID:21741372 PMID:23711929 PMID:25034532 PMID:31837377 PMID:34599545 |
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NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BMAL1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
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G |
Bmp5 |
bone morphogenetic protein 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BMP5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:75,682,647...75,807,598
Ensembl chr 9:75,682,646...75,807,592
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G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions |
ISO |
[Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of BMP7 mRNA |
CTD |
PMID:21051528 |
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NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
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G |
Bnip3 |
BCL2/adenovirus E1B interacting protein 3 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of BNIP3 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein] |
CTD |
PMID:19442826 PMID:36739042 |
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NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
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G |
Bnip3l |
BCL2/adenovirus E1B interacting protein 3-like |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of BNIP3L protein] |
CTD |
PMID:34861471 |
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NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326
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G |
Bpgm |
2,3-bisphosphoglycerate mutase |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of BPGM mRNA |
CTD |
PMID:16084531 |
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NCBI chr 6:34,453,291...34,482,071
Ensembl chr 6:34,453,142...34,482,548
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G |
Btg1 |
BTG anti-proliferation factor 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of BTG1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr10:96,452,863...96,458,675
Ensembl chr10:96,452,868...96,458,671
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G |
C3 |
complement component 3 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of C3 protein modified form]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C3 protein] |
CTD |
PMID:20946910 PMID:32924446 |
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NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
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G |
Cacna1g |
calcium channel, voltage-dependent, T type, alpha 1G subunit |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CACNA1G mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:94,299,217...94,365,226
Ensembl chr11:94,299,217...94,365,024
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G |
Capn1 |
calpain 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of CAPN1 protein] |
CTD |
PMID:25451595 |
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NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927
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G |
Capn2 |
calpain 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of CAPN2 protein] |
CTD |
PMID:25451595 |
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NCBI chr 1:182,294,818...182,345,175
Ensembl chr 1:182,294,825...182,345,173
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G |
Casp1 |
caspase 1 |
multiple interactions increases cleavage |
ISO EXP |
[Acetylcysteine co-treated with Cobalt] results in decreased expression of CASP1 protein; Acetylcysteine affects the reaction [diallyl trisulfide results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP1 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of CASP1 mRNA]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [Cobalt results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [Ethanol results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of and results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [piperlongumine results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [TNF protein results in increased cleavage of and results in increased activity of CASP1 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]] Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of CASP1 mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide inhibits the reaction [anthrax toxin results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [bisphenol A results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein] Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of CASP1 protein] Acetylcysteine results in increased cleavage of CASP1 protein |
CTD |
PMID:23940760 PMID:24337744 PMID:24885895 PMID:25929180 PMID:26079697 PMID:26086368 PMID:26435000 PMID:26809137 PMID:26901245 PMID:27783111 PMID:28004443 PMID:28814068 PMID:30205151 PMID:30878009 PMID:30977640 PMID:32805375 PMID:34217685 PMID:34238121 PMID:34510229 PMID:34791735 PMID:35190838 PMID:36055550 PMID:36347317 PMID:36354081 PMID:36646296 PMID:37300869 PMID:37393521 PMID:37692514 PMID:38242274 PMID:38821455 PMID:39260547 More...
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NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
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G |
Casp12 |
caspase 12 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of and results in increased activity of CASP12 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of CASP12 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP12 protein]] Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP12 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP12 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP12 protein] |
CTD |
PMID:18077580 PMID:21145380 PMID:21616140 PMID:25451595 PMID:28296042 PMID:31330229 PMID:37300854 More...
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NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
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G |
Casp14 |
caspase 14 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CASP14 protein] |
CTD |
PMID:16137721 |
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NCBI chr10:78,547,829...78,554,181
Ensembl chr10:78,547,825...78,554,128
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G |
Casp2 |
caspase 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] Acetylcysteine inhibits the reaction [[CASP2 protein affects the susceptibility to Rotenone] which results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased cleavage of CASP2 protein] Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP2 protein] |
CTD |
PMID:15158148 PMID:17041759 PMID:21216964 PMID:30408460 |
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NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions increases activity decreases activity increases expression |
ISO EXP |
Acetylcysteine results in increased cleavage of CASP3 protein [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Acetylcysteine affects the reaction [nonylphenol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [mancozeb results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [nitrofen results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [POMC protein promotes the reaction [cobaltous chloride results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Acetylcysteine results in increased expression of CASP3 protein modified form] Acetylcysteine results in increased activity of CASP3 Acetylcysteine results in decreased activity of CASP3 protein [Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [6-iodo-5-hydroxy-eicosatrienoic acid, delta-lactone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]; Acetylcysteine inhibits the reaction [[alpha-pyrrolidinononanophenone analog co-treated with Tretinoin] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Naphthalimides co-treated with Spermidine] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [[Pentachlorophenol co-treated with copper-1,10-phenanthroline] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Vitamin K 2 co-treated with Arsenic Trioxide] results in increased expression of CASP3]; Acetylcysteine inhibits the reaction [ABBV-744 results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [alpha-pyrrolidinononanophenone analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [alpha-pyrrolidinononanophenone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [aristolochic acid I results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [butein results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [chelerythrine results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [chromium tripicolinate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [crocin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [dimethoxycurcumin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Eosine I Bluish results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [fenpyroximate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [glabridin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hesperetin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [isoliensinine results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [manumycin results in increased activity of CASP3]; Acetylcysteine inhibits the reaction [menadione epoxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [osimertinib results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [platycodin D results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Prodigiosin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Propofol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Reactive Oxygen Species results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [surfactin peptide results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased cleavage of CASP3 protein]; Acetylcysteine promotes the reaction [brazilin results in increased activity of CASP3 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP3 protein]; Acetylcysteine promotes the reaction [sinularin results in increased cleavage of CASP3 protein]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased cleavage of CASP3 protein]; Oxygen deficiency affects the reaction [Acetylcysteine results in increased activity of CASP3 protein] [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [4-nonylphenol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [arsenite results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Diquat results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Estradiol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP3]; Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [JP8 aviation fuel results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Lead results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [menadione epoxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Pilocarpine results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Propranolol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of CASP3 protein modified form] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP3 protein in the stomach) N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases cleavage of CASP3 protein in stomach] |
CTD RGD |
PMID:11969376 PMID:12168106 PMID:12750841 PMID:12754411 PMID:14660655 PMID:15050407 PMID:15158148 PMID:15375156 PMID:15496615 PMID:15545282 PMID:15582350 PMID:15683462 PMID:15816534 PMID:16014620 PMID:16169029 PMID:16282376 PMID:17041759 PMID:17136323 PMID:17309078 PMID:17332930 PMID:17468103 PMID:17542780 PMID:17574045 PMID:17888894 PMID:18077580 PMID:18281123 PMID:18483861 PMID:18547707 PMID:18703135 PMID:18791325 PMID:18804340 PMID:19014919 PMID:19082730 PMID:19376147 PMID:19409983 PMID:19477266 PMID:19523979 PMID:19536524 PMID:19722195 PMID:19771260 PMID:19837105 PMID:19840221 PMID:20100472 PMID:20114059 PMID:20362650 PMID:20594983 PMID:20632440 PMID:20674558 PMID:20883752 PMID:20946910 PMID:20981856 PMID:21145380 PMID:21166495 PMID:21221209 PMID:21242791 PMID:21300145 PMID:21310227 PMID:21349322 PMID:21418039 PMID:21453688 PMID:21533816 PMID:21549813 PMID:21565247 PMID:21600974 PMID:21616140 PMID:21741372 PMID:21804221 PMID:21843585 PMID:21998720 PMID:22002103 PMID:22085843 PMID:22260869 PMID:22440610 PMID:22578287 PMID:22710416 PMID:22714038 PMID:22824136 PMID:22909951 PMID:22922937 PMID:23088786 PMID:23405080 PMID:23677851 PMID:23711929 PMID:23836369 PMID:23867903 PMID:24036456 PMID:24157283 PMID:24273890 PMID:24291486 PMID:24299490 PMID:24412703 PMID:24614525 PMID:24634002 PMID:24908156 PMID:24998639 PMID:25034532 PMID:25341683 PMID:25568320 PMID:25845326 PMID:25891866 PMID:25940438 PMID:25947082 PMID:26079211 PMID:26124276 PMID:26219228 PMID:26282491 PMID:26549478 PMID:26588882 PMID:26630137 PMID:26772155 PMID:26804764 PMID:27106530 PMID:27417252 PMID:27484784 PMID:27539140 PMID:28025121 PMID:28063998 PMID:28219700 PMID:28237877 PMID:28296042 PMID:28548367 PMID:28578026 PMID:28778520 PMID:28804952 PMID:28918123 PMID:28993239 PMID:29087013 PMID:29108775 PMID:29111403 PMID:29248572 PMID:29432840 PMID:29454061 PMID:29484840 PMID:29774349 PMID:29944906 PMID:29945211 PMID:30037311 PMID:30236763 PMID:30240709 PMID:30259999 PMID:30590774 PMID:30633982 PMID:30641872 PMID:30769050 PMID:30796935 PMID:30871965 PMID:30917517 PMID:31077745 PMID:31157476 PMID:31173782 PMID:31229567 PMID:31313457 PMID:31330229 PMID:31381934 PMID:31408635 PMID:31433961 PMID:32506763 PMID:32540572 PMID:32662599 PMID:32708634 PMID:32924446 PMID:33031904 PMID:33485121 PMID:33592258 PMID:33797725 PMID:33961949 PMID:34303041 PMID:34547296 PMID:34627931 PMID:34816377 PMID:34850538 PMID:34861471 PMID:34897981 PMID:35085590 PMID:35123993 PMID:35130734 PMID:35396826 PMID:35430258 PMID:35622622 PMID:35738838 PMID:35810264 PMID:36029289 PMID:36070022 PMID:36252918 PMID:36493885 PMID:36801614 PMID:36933581 PMID:37084995 PMID:37146930 PMID:37308051 PMID:37487865 PMID:37499777 PMID:37769529 PMID:38040126 PMID:38521250 PMID:29408335 PMID:32106377 More...
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RGD:127284846, RGD:127284886 |
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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|
G |
Casp4 |
caspase 4, apoptosis-related cysteine peptidase |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CASP4 mRNA] Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP4 mRNA] Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP4 protein] |
CTD |
PMID:16137721 PMID:19477266 PMID:22922937 PMID:25341683 |
|
NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
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G |
Casp6 |
caspase 6 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP6 protein]; Acetylcysteine inhibits the reaction [surfactin peptide results in increased cleavage of and results in increased activity of CASP6 protein] Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP6 protein] Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein] |
CTD |
PMID:15158148 PMID:19954742 PMID:24157283 PMID:37146930 |
|
NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752
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|
G |
Casp7 |
caspase 7 |
multiple interactions decreases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP7 mRNA] Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP7 protein] Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP7 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein] Acetylcysteine results in decreased expression of CASP7 protein modified form |
CTD |
PMID:17136323 PMID:19771260 PMID:20594983 PMID:21145380 PMID:21549813 PMID:21843585 PMID:22085843 PMID:22260869 PMID:22909951 PMID:23405080 PMID:24157283 PMID:24998639 PMID:25824409 PMID:27106530 PMID:27539140 PMID:28087840 PMID:28161410 PMID:29800641 PMID:30408460 PMID:30917517 PMID:31313457 PMID:31330229 PMID:31433961 PMID:34627931 PMID:36252918 PMID:37146930 More...
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NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
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G |
Casp8 |
caspase 8 |
multiple interactions |
EXP ISO |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of CASP8 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of CASP8 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of CASP8 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of CASP8 protein]]; Acetylcysteine inhibits the reaction [cannabidiol hydroxyquinone results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP8 protein] Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in decreased expression of CASP8 mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in decreased expression of CASP8 protein]]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP8 mRNA]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [sinularin results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP8 protein]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased activity of and results in increased cleavage of CASP8 protein] [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein]; [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of CASP8 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP8 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of CASP8 protein] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP8 protein in the stomach) |
CTD RGD |
PMID:16169029 PMID:17574045 PMID:18791325 PMID:19014919 PMID:19477266 PMID:20184945 PMID:20576514 PMID:20674558 PMID:20883752 PMID:20946910 PMID:21310227 PMID:22578287 PMID:23711929 PMID:23867903 PMID:24614525 PMID:25034532 PMID:25845326 PMID:27313093 PMID:27484784 PMID:28087840 PMID:28219700 PMID:28548367 PMID:28918123 PMID:29432840 PMID:30917517 PMID:32506763 PMID:32662599 PMID:35833596 PMID:37422542 PMID:29408335 More...
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RGD:127284846 |
NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [monomethylarsonous acid results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP9 protein]]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP9 protein] [Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP9 protein; [saikosaponin D co-treated with Acetylcysteine] results in decreased expression of CASP9 protein; Acetylcysteine affects the reaction [SOD2 protein affects the activity of CASP9 protein]; Acetylcysteine inhibits the reaction [10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [ganoderic acid analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [oenothein B results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Propofol results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [sinularin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Soot analog results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP9 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP9 protein] Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [CASP9 protein binds to CYCS protein]]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP9]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein] Acetylcysteine results in increased expression of CASP9 protein; Acetylcysteine results in increased expression of CASP9 protein modified form N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP9 protein in the stomach) N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases cleavage of CASP9 protein in stomach] |
CTD RGD |
PMID:15158148 PMID:15496615 PMID:16169029 PMID:17309078 PMID:17574045 PMID:18336854 PMID:18483861 PMID:18594523 PMID:18629305 PMID:18791325 PMID:19082730 PMID:19477266 PMID:19771260 PMID:20576514 PMID:20848084 PMID:21145380 PMID:21166495 PMID:21310227 PMID:21418039 PMID:21549813 PMID:21616140 PMID:22002103 PMID:22085843 PMID:22578287 PMID:22714038 PMID:23088786 PMID:23405080 PMID:23711929 PMID:23867903 PMID:24157283 PMID:24614525 PMID:24634002 PMID:25845326 PMID:25940438 PMID:26282491 PMID:27313093 PMID:27539140 PMID:28296042 PMID:28548367 PMID:28804952 PMID:28918123 PMID:29108775 PMID:29432840 PMID:29945211 PMID:29962303 PMID:30240709 PMID:30408460 PMID:30452899 PMID:30769050 PMID:30917517 PMID:31313457 PMID:31330229 PMID:31433961 PMID:32662599 PMID:34627931 PMID:35396826 PMID:37084995 PMID:37209937 PMID:29408335 PMID:32106377 More...
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RGD:127284846, RGD:127284886 |
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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G |
Cat |
catalase |
multiple interactions increases expression decreases activity |
ISO EXP |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Carmustine results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Diclofenac results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dimethoate results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dimethylnitrosamine results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Zinc results in decreased expression of CAT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]] Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of CAT protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Ethanol results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased activity of CAT protein]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased activity of CAT protein] Acetylcysteine results in increased expression of CAT protein Acetylcysteine results in decreased activity of CAT protein [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Particulate Matter results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [ceric oxide results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Chlorine results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos affects the activity of CAT protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Propofol results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Smoke analog results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of CAT mRNA]; CAT protein inhibits the reaction [Acetylcysteine results in increased abundance of Hydrogen Peroxide] |
CTD |
PMID:7491977 PMID:16169029 PMID:19840221 PMID:19853593 PMID:20332008 PMID:21114986 PMID:21131394 PMID:22416658 PMID:22427991 PMID:23416263 PMID:24299490 PMID:24485406 PMID:24577230 PMID:24810974 PMID:26079211 PMID:26257840 PMID:26769589 PMID:27235710 PMID:27246665 PMID:28012895 PMID:28013216 PMID:28108387 PMID:28535741 PMID:28804952 PMID:29143438 PMID:30037311 PMID:30423402 PMID:30769050 PMID:30951941 PMID:30998386 PMID:31157476 PMID:32023790 PMID:32402895 PMID:33882750 PMID:34425170 PMID:34547296 PMID:34767868 PMID:34856488 PMID:35065218 PMID:35430258 PMID:37458150 PMID:38488660 More...
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NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Cav1 |
caveolin 1, caveolae protein |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of CAV1 Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of CAV1 protein]; Acetylcysteine inhibits the reaction [Rosiglitazone results in increased expression of CAV1]; Acetylcysteine results in increased ubiquitination of and results in increased degradation of CAV1 protein; Hydrogen Peroxide inhibits the reaction [Acetylcysteine results in increased ubiquitination of and results in increased degradation of CAV1 protein] |
CTD |
PMID:18507034 PMID:21148404 PMID:35349355 |
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NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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G |
Cbs |
cystathionine beta-synthase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Rotenone results in decreased expression of CBS protein] |
CTD |
PMID:25086357 |
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NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212
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G |
Ccdc85c |
coiled-coil domain containing 85C |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased localization of CCDC85C protein] |
CTD |
PMID:38185225 |
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NCBI chr12:108,169,858...108,244,111
Ensembl chr12:108,169,861...108,241,684
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CCL11 mRNA Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CCL11 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL11 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL11 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of CCL11 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of CCL11 protein] |
CTD |
PMID:12576300 PMID:22129741 PMID:26138014 |
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NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
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G |
Ccl17 |
C-C motif chemokine ligand 17 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CCL17 protein] |
CTD |
PMID:26138014 |
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NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Acetylcysteine inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CCL2 mRNA] Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]] Acetylcysteine affects the reaction [Doxorubicin results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]] |
CTD |
PMID:10541287 PMID:11124598 PMID:15139008 PMID:17529908 PMID:18303122 PMID:19158351 PMID:22700867 PMID:26332274 PMID:26683377 PMID:28555929 PMID:33146789 PMID:35065218 PMID:35123994 More...
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NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of CCL20 mRNA |
CTD |
PMID:22385246 |
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NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of CCL22 mRNA] |
CTD |
PMID:19350554 |
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NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327
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G |
Ccl24 |
C-C motif chemokine ligand 24 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CCL24 protein] |
CTD |
PMID:26138014 |
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NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions decreases secretion |
EXP |
[Acetylcysteine co-treated with Particulate Matter] results in increased secretion of CCL3 protein; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CCL3 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL3 mRNA]; Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of CCL3 protein]]; Acetylcysteine promotes the reaction [Polymyxin B results in decreased secretion of CCL3 protein]; MYD88 protein affects the reaction [[Acetylcysteine co-treated with Particulate Matter] results in increased secretion of CCL3 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL3 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine results in decreased secretion of CCL3 protein] |
CTD |
PMID:21765237 PMID:28555929 |
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NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CCL5 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CCL5 mRNA] |
CTD |
PMID:10495789 PMID:11167962 PMID:26138014 PMID:33146789 |
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NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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G |
Ccl8 |
C-C motif chemokine ligand 8 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CCL8 protein] |
CTD |
PMID:26138014 |
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NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625
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G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]; Cycloheximide inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein] Acetylcysteine results in increased expression of CCN1 mRNA; Acetylcysteine results in increased expression of CCN1 protein |
CTD |
PMID:21055460 |
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NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] |
CTD |
PMID:17270171 |
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NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
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G |
Ccna1 |
cyclin A1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CCNA1 protein] |
CTD |
PMID:20654705 |
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NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922
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G |
Ccna2 |
cyclin A2 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCNA2 protein] Acetylcysteine inhibits the reaction [alpha-terthienylmethanol results in increased expression of CCNA2 protein] |
CTD |
PMID:24909818 PMID:28506552 |
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NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
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G |
Ccnb1 |
cyclin B1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]; Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CCNB1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]; Acetylcysteine inhibits the reaction [sinularin results in decreased phosphorylation of CCNB1 protein] |
CTD |
PMID:24909818 PMID:25633853 PMID:28548367 PMID:29128613 |
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NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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G |
Ccnd1 |
cyclin D1 |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [[Vorinostat co-treated with Butyrates] results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of CCND1 protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Hydrocarbons, Chlorinated analog results in increased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of CCND1 protein] Acetylcysteine results in decreased expression of CCND1 protein Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in decreased expression of CCND1 protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of CCND1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of CCND1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 protein] |
CTD |
PMID:15173093 PMID:15897899 PMID:17602960 PMID:18563748 PMID:19409983 PMID:21600978 PMID:23948867 PMID:24355586 PMID:24909818 PMID:24968063 PMID:26332274 PMID:28321046 PMID:31433961 PMID:33485121 PMID:34627931 More...
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NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Ccnd2 |
cyclin D2 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of CCND2 protein]; Acetylcysteine inhibits the reaction [Methoxychlor results in decreased expression of CCND2 mRNA] Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCND2 mRNA] Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND2 protein] |
CTD |
PMID:19615393 PMID:26332274 PMID:33485121 PMID:34627931 |
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NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
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G |
Ccnd3 |
cyclin D3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND3 protein] |
CTD |
PMID:34627931 |
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NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
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G |
Ccne1 |
cyclin E1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of CCNE1 mRNA] Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCNE1 protein] |
CTD |
PMID:15945272 PMID:24909818 |
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NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
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G |
Ccne2 |
cyclin E2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CCNE2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
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G |
Cd14 |
CD14 antigen |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Iron deficiency results in increased expression of CD14 protein] |
CTD |
PMID:20368581 |
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NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
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G |
Cd36 |
CD36 molecule |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNA] Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 protein]; CD36 mRNA promotes the reaction [Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased uptake of malondialdehyde-low density lipoprotein, human]] Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 protein] |
CTD |
PMID:22824115 PMID:26187465 PMID:33007364 PMID:35622622 PMID:36534932 |
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NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
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G |
Cd40lg |
CD40 ligand |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CD40LG mRNA] Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein] |
CTD |
PMID:19477266 PMID:27634759 |
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NCBI chr X:56,257,448...56,269,402
Ensembl chr X:56,257,503...56,269,402
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G |
Cd86 |
CD86 antigen |
multiple interactions |
ISO |
Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of CD86 protein]; Acetylcysteine inhibits the reaction [1,10-phenanthroline results in increased expression of CD86 mRNA]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Ethylmercuric Chloride results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Thimerosal results in increased expression of CD86 protein] |
CTD |
PMID:19033392 PMID:19641517 PMID:20417223 PMID:20457211 PMID:30842373 |
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NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
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G |
Cdc25c |
cell division cycle 25C |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CDC25C protein modified form] |
CTD |
PMID:25633853 |
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NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586
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G |
Cdh1 |
cadherin 1 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; Acetylcysteine inhibits the reaction [DDT results in decreased expression of CDH1 mRNA]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased methylation of CDH1 promoter]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of CDH1 protein] Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in decreased expression of CDH1 protein] Acetylcysteine results in increased expression of CDH1 protein |
CTD |
PMID:18791180 PMID:22648416 PMID:24820114 PMID:28284859 PMID:32659284 PMID:32687844 PMID:32687961 PMID:34687772 PMID:38488660 More...
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NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
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G |
Cdh11 |
cadherin 11 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDH11 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:103,358,727...103,512,125
Ensembl chr 8:103,358,727...103,512,274
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G |
Cdh13 |
cadherin 13 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of CDH13 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 8:119,010,150...120,051,668
Ensembl chr 8:119,010,472...120,051,660
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G |
Cdh2 |
cadherin 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH2 protein] Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of CDH2 mRNA] Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of CDH2 protein] |
CTD |
PMID:23876460 PMID:24820114 PMID:28284859 PMID:38488660 |
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NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
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G |
Cdh5 |
cadherin 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein] |
CTD |
PMID:33131013 |
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NCBI chr 8:104,828,247...104,871,136
Ensembl chr 8:104,828,257...104,871,143
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G |
Cdk1 |
cyclin dependent kinase 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CDK1 protein] Acetylcysteine inhibits the reaction [ovatodiolide results in decreased expression of CDK1 protein]; Acetylcysteine inhibits the reaction [sinularin results in decreased phosphorylation of CDK1 protein] |
CTD |
PMID:25633853 PMID:28548367 PMID:39276908 |
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NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [ovatodiolide results in decreased expression of CDK2 protein] |
CTD |
PMID:39276908 |
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NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
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G |
Cdk4 |
cyclin dependent kinase 4 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Methoxychlor results in decreased expression of CDK4 mRNA] Acetylcysteine inhibits the reaction [tubocapsenolide A results in increased degradation of CDK4 protein] |
CTD |
PMID:18442981 PMID:19615393 |
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NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
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G |
Cdk7 |
cyclin dependent kinase 7 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CDK7 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr13:100,833,532...100,867,454
Ensembl chr13:100,839,139...100,867,447
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G |
Cdkn1a |
cyclin dependent kinase inhibitor 1A |
multiple interactions increases expression decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of CDKN1A]; Acetylcysteine inhibits the reaction [diaziquone results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [ethylenimine quinone results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1A enhancer]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]] Acetylcysteine results in increased expression of CDKN1A protein [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDKN1A mRNA; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone results in increased expression of CDKN1A protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of CDKN1A protein] Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [dihydrolipoic acid results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of CDKN1A protein] Acetylcysteine results in decreased expression of CDKN1A mRNA |
CTD |
PMID:8943236 PMID:9343371 PMID:12208374 PMID:15496615 PMID:15978937 PMID:17602960 PMID:18022818 PMID:19409983 PMID:21462292 PMID:21565247 PMID:22129741 PMID:22183962 PMID:22927544 PMID:24792323 PMID:26332274 PMID:26658076 PMID:30555576 PMID:32473187 PMID:33961949 PMID:35303175 PMID:36154299 PMID:36493885 PMID:36801614 PMID:38604309 More...
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NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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G |
Cdkn1b |
cyclin dependent kinase inhibitor 1B |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of CDKN1B protein Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of CDKN1B protein] Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of CDKN1B protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1B enhancer] |
CTD |
PMID:17602960 PMID:18022818 PMID:30917517 |
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NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
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G |
Cdkn2a |
cyclin dependent kinase inhibitor 2A |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN2A protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN2A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN2A protein] Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [DNMT1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [EZH2 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [KDM2A protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [TET1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN2A protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN2A mRNA]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN2A mRNA]] |
CTD |
PMID:31551408 PMID:32473187 PMID:35303175 |
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NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of CEBPA protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CEBPA protein] |
CTD |
PMID:27117918 PMID:35622622 |
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NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA] |
CTD |
PMID:21220312 |
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NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
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G |
Cebpe |
CCAAT/enhancer binding protein epsilon |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]] |
CTD |
PMID:29945211 |
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NCBI chr14:54,947,823...54,949,604
Ensembl chr14:54,947,817...54,949,631
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of CFLAR protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of CFLAR protein]; Acetylcysteine inhibits the reaction [lactucin results in decreased expression of CFLAR protein]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in decreased expression of CFLAR protein modified form]] |
CTD |
PMID:25034532 PMID:25619640 PMID:34302634 PMID:34599545 |
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NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
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G |
Cftr |
cystic fibrosis transmembrane conductance regulator |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR protein] |
CTD |
PMID:19061877 |
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NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
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G |
Chat |
choline O-acetyltransferase |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of CHAT protein [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein] |
CTD |
PMID:25891525 |
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NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
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G |
Chek1 |
checkpoint kinase 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CHEK1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK1 protein]] Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CHEK1 protein modified form] |
CTD |
PMID:15489221 PMID:25633853 PMID:33971260 |
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NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361
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G |
Chek2 |
checkpoint kinase 2 |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CHEK2 protein modified form]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of CHEK2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased phosphorylation of CHEK2 protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased expression of CHEK2 protein] Acetylcysteine results in increased expression of CHEK2 protein |
CTD |
PMID:15489221 PMID:23274516 PMID:24792323 PMID:24933654 PMID:31715134 |
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NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
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G |
Chka |
choline kinase alpha |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CHKA mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:3,901,585...3,944,368
Ensembl chr19:3,901,773...3,944,369
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G |
Chrm2 |
cholinergic receptor, muscarinic 2, cardiac |
multiple interactions |
ISO EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CHRM2 mRNA Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM2 mRNA] |
CTD |
PMID:22129741 PMID:29253600 |
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NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
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G |
Chrm3 |
cholinergic receptor, muscarinic 3, cardiac |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM3 mRNA] |
CTD |
PMID:29253600 |
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NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
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G |
Chrm4 |
cholinergic receptor, muscarinic 4 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM4 mRNA] |
CTD |
PMID:29253600 |
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NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033
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G |
Chuk |
conserved helix-loop-helix ubiquitous kinase |
decreases activity |
ISO |
Acetylcysteine results in decreased activity of CHUK protein |
CTD |
PMID:17395010 |
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NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
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G |
Cish |
cytokine inducible SH2-containing protein |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CISH mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983
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G |
Ckb |
creatine kinase, brain |
multiple interactions |
ISO |
[Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Acetaminophen results in decreased activity of CKB protein]; [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CKB protein] |
CTD |
PMID:19688255 |
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NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772
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G |
Ckm |
creatine kinase, muscle |
multiple interactions decreases secretion |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CKM mRNA] Acetylcysteine results in decreased secretion of CKM protein |
CTD |
PMID:9689591 PMID:21912612 |
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NCBI chr 7:19,145,019...19,155,508
Ensembl chr 7:19,138,701...19,156,766
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G |
Cldn1 |
claudin 1 |
multiple interactions |
ISO EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CLDN1 mRNA; Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CLDN1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of CLDN1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN1 mRNA] |
CTD |
PMID:22129741 PMID:28115242 PMID:29235125 PMID:32687961 PMID:33485121 PMID:34906888 More...
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NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
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G |
Cldn4 |
claudin 4 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN4 mRNA] |
CTD |
PMID:23816505 PMID:33485121 |
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NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788
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G |
Cldn5 |
claudin 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of and affects the localization of CLDN5 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of CLDN5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CLDN5 protein] |
CTD |
PMID:28115242 PMID:34391839 |
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NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012
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G |
Clec9a |
C-type lectin domain family 9, member a |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CLEC9A mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:129,385,825...129,401,727
Ensembl chr 6:129,385,825...129,401,726
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G |
Clk1 |
CDC-like kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of CLK1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 1:58,451,147...58,463,247
Ensembl chr 1:58,449,348...58,463,225
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G |
Clu |
clusterin |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Chlorine results in increased expression of CLU protein] |
CTD |
PMID:35065218 |
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NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
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G |
Cma1 |
chymase 1, mast cell |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CMA1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:56,178,908...56,182,132
Ensembl chr14:56,178,908...56,182,132
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G |
Cntf |
ciliary neurotrophic factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CNTF protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] |
CTD |
PMID:16896058 PMID:26138014 |
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NCBI chr19:12,740,892...12,742,996
Ensembl chr19:12,741,024...12,742,996
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G |
Col18a1 |
collagen, type XVIII, alpha 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of COL18A1 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of COL18A1 protein] |
CTD |
PMID:13679210 |
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NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382
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G |
Col1a1 |
collagen, type I, alpha 1 |
decreases expression multiple interactions |
ISO EXP |
Acetylcysteine results in decreased expression of COL1A1 mRNA Acetylcysteine results in decreased expression of COL1A1 mRNA; Acetylcysteine results in decreased expression of COL1A1 protein Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of COL1A1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 protein] Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of COL1A1 mRNA]; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of COL1A1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of COL1A1 protein] |
CTD |
PMID:11710721 PMID:17602960 PMID:32659284 PMID:34547296 PMID:36493885 PMID:38488660 More...
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NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
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G |
Col1a2 |
collagen, type I, alpha 2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of COL1A2 mRNA |
CTD |
PMID:11710721 |
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NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
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G |
Col4a1 |
collagen, type IV, alpha 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of COL4A1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
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G |
Colq |
collagen like tail subunit of asymmetric acetylcholinesterase |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of COLQ mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of COLQ mRNA] |
CTD |
PMID:22129741 |
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NCBI chr14:31,245,039...31,299,820
Ensembl chr14:31,245,039...31,313,300
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G |
Copg1 |
coatomer protein complex, subunit gamma 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of COPG1 mRNA] |
CTD |
PMID:34425375 |
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NCBI chr 6:87,864,801...87,890,577
Ensembl chr 6:87,864,796...87,890,577
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G |
Cox4i1 |
cytochrome c oxidase subunit 4I1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of COX4I1 mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of COX4I1 mRNA] |
CTD |
PMID:35403558 PMID:36493885 |
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NCBI chr 8:121,394,964...121,400,948
Ensembl chr 8:121,394,961...121,400,946
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G |
Cpe |
carboxypeptidase E |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of CPE mRNA |
CTD |
PMID:16084531 |
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NCBI chr 8:65,045,576...65,146,143
Ensembl chr 8:65,045,576...65,146,088
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G |
Cplx1 |
complexin 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CPLX1 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 5:108,666,420...108,697,893
Ensembl chr 5:108,666,420...108,697,890
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G |
Cpt1a |
carnitine palmitoyltransferase 1a, liver |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Dietary Fats] results in increased expression of CPT1A mRNA |
CTD |
PMID:21051528 |
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NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
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G |
Cpt1b |
carnitine palmitoyltransferase 1b, muscle |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CPT1B mRNA |
CTD |
PMID:22129741 |
|
NCBI chr15:89,300,608...89,310,065
Ensembl chr15:89,300,608...89,310,066
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G |
Cradd |
CASP2 and RIPK1 domain containing adaptor with death domain |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of CRADD mRNA |
CTD |
PMID:16084531 |
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NCBI chr10:95,010,601...95,160,000
Ensembl chr10:95,010,608...95,159,995
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G |
Crat |
carnitine acetyltransferase |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CRAT mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:30,290,483...30,305,602
Ensembl chr 2:30,290,483...30,305,825
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in decreased phosphorylation of CREB1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of CREB1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of CREB1 protein] Acetylcysteine inhibits the reaction [4-biphenylamine results in increased expression of CREB1 protein] |
CTD |
PMID:18375950 PMID:32433928 PMID:36813253 PMID:38642822 |
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NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
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G |
Crem |
cAMP responsive element modulator |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CREM mRNA] |
CTD |
PMID:25381014 |
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NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
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G |
Cry1 |
cryptochrome circadian regulator 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CRY1 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
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G |
Cryab |
crystallin, alpha B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenite results in increased expression of CRYAB protein] |
CTD |
PMID:15175009 |
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NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936
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G |
Cryga |
crystallin, gamma A |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CRYGA mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CRYGA mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 1:65,139,552...65,142,532
Ensembl chr 1:65,139,548...65,142,532
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G |
Cs |
citrate synthase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of CS mRNA] Acetylcysteine promotes the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of CS protein]] |
CTD |
PMID:21775390 PMID:27385396 PMID:36762617 |
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NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348
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G |
Csf1 |
colony stimulating factor 1 (macrophage) |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CSF1 mRNA] |
CTD |
PMID:35123994 |
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NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
EXP |
[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of ATP6V0D2 mRNA; [Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:30742845 |
|
NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
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G |
Csf2 |
colony stimulating factor 2 (granulocyte-macrophage) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein] |
CTD |
PMID:10645887 PMID:19460412 PMID:26138014 PMID:29753051 |
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NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
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G |
Csf3r |
colony stimulating factor 3 receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]] |
CTD |
PMID:29945211 |
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NCBI chr 4:125,917,241...125,938,233
Ensembl chr 4:125,918,343...125,938,233
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G |
Cst3 |
cystatin C |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CST3 protein] |
CTD |
PMID:35020164 |
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NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased phosphorylation of CTNNB1 protein] Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CTNNB1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in increased cleavage of CTNNB1 protein]; Acetylcysteine inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CTNNB1 protein] |
CTD |
PMID:16282376 PMID:19436114 PMID:24961358 PMID:24968063 PMID:28321046 PMID:28343033 PMID:33131013 More...
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NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
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G |
Ctrc |
chymotrypsin C |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CTRC mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 4:141,565,550...141,573,598
Ensembl chr 4:141,565,550...141,573,670
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G |
Ctrl |
chymotrypsin-like |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [plumbagin results in decreased activity of CTRL protein] |
CTD |
PMID:31276663 |
|
NCBI chr 8:106,658,626...106,660,494
Ensembl chr 8:106,658,635...106,660,494
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G |
Ctsb |
cathepsin B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-monochloropropane-1, 2 diol ester results in increased secretion of CTSB protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CTSB mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CTSB mRNA] |
CTD |
PMID:29307831 PMID:31319114 PMID:38408632 |
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NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
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G |
Ctsd |
cathepsin D |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of CTSD mRNA] |
CTD |
PMID:35550146 |
|
NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775
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G |
Ctsk |
cathepsin K |
multiple interactions |
EXP |
[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CTSK protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:30742845 PMID:38971422 |
|
NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
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G |
Ctsl |
cathepsin L |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Berberine results in decreased cleavage of CTSL protein] |
CTD |
PMID:36070022 |
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NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
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G |
Cux2 |
cut-like homeobox 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CUX2 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CUX2 mRNA] |
CTD |
PMID:22129741 |
|
NCBI chr 5:121,996,025...122,188,522
Ensembl chr 5:121,994,429...122,188,165
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of CXCL1 protein Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of CXCL1 protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein] |
CTD |
PMID:17395010 PMID:18257742 |
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NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CXCL12 protein] Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CXCL12 mRNA] |
CTD |
PMID:26138014 PMID:35123994 |
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NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
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G |
Cxcl15 |
C-X-C motif chemokine ligand 15 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of CXCL8 mRNA Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [[Oligomycins co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [acetylleucyl-leucyl-norleucinal results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Anthralin results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 mRNA]]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Benzene results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased expression of CXCL8]; Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Chloroquine results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [citral results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [ethylenediamine results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Ethylmercuric Chloride results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Eugenol results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [lactacystin results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [MG 262 results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CXCL8]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Thimerosal results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [vanadium pentoxide results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased secretion of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein] |
CTD |
PMID:8123758 PMID:9628260 PMID:9707512 PMID:10022265 PMID:10202011 PMID:10696066 PMID:11306435 PMID:12208513 PMID:15139008 PMID:16076765 PMID:17922515 PMID:20457211 PMID:21316925 PMID:21533553 PMID:21777978 PMID:21779360 PMID:21920952 PMID:22385246 PMID:22549761 PMID:22867088 PMID:24570342 PMID:26160521 PMID:26303504 PMID:27393034 PMID:27427241 PMID:27917510 PMID:29227181 PMID:29731195 PMID:31622892 PMID:32687961 PMID:33146789 PMID:34890707 PMID:35065218 More...
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NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of CXCL2 mRNA]; Acetylcysteine inhibits the reaction [Vanadates results in increased expression of CXCL2 mRNA] Acetylcysteine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CXCL2 protein] |
CTD |
PMID:10718115 PMID:16919916 PMID:19350554 PMID:21507677 |
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NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
decreases expression multiple interactions |
ISO EXP |
Acetylcysteine results in decreased expression of CXCL1 protein Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]] |
CTD |
PMID:17395010 PMID:24316229 PMID:28555929 |
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NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
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G |
Cxcl5 |
C-X-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CXCL6 protein] |
CTD |
PMID:26138014 |
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NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483
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G |
Cyba |
cytochrome b-245, alpha polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CYBA protein] |
CTD |
PMID:21195169 |
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NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
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G |
Cybb |
cytochrome b-245, beta polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CYBB protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CYBB protein] |
CTD |
PMID:21195169 PMID:29087013 |
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NCBI chr X:9,301,493...9,354,005
Ensembl chr X:9,301,491...9,354,010
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G |
Cycs |
cytochrome c, somatic |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [dimethoxycurcumin affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [sodium arsenite affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [surfactin peptide affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein] Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of CYCS mRNA]; Acetylcysteine inhibits the reaction [Methylmercury Compounds affects the localization of CYCS protein] Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [arsenic trioxide affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [CASP9 protein binds to CYCS protein]]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CYCS mRNA] Acetylcysteine results in decreased expression of CYCS protein |
CTD |
PMID:18483861 PMID:19536524 PMID:19954742 PMID:21145380 PMID:21221209 PMID:21549813 PMID:22085843 PMID:23711929 PMID:24634002 PMID:28296042 PMID:29248572 PMID:34547296 PMID:35123993 PMID:35396826 PMID:37084995 More...
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NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
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G |
Cyct |
cytochrome c, testis |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Estradiol results in increased expression of CYCT protein] |
CTD |
PMID:15545282 |
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NCBI chr 2:76,184,286...76,190,797
Ensembl chr 2:76,184,286...76,190,794
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of CYP11A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein] |
CTD |
PMID:26769589 PMID:29567110 |
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NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
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G |
Cyp11b2 |
cytochrome P450, family 11, subfamily b, polypeptide 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of CYP11B2 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of CYP11B2 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of CYP11B2 mRNA] |
CTD |
PMID:25617244 |
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NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,467...74,728,167
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein] |
CTD |
PMID:29567110 |
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NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CYP19A1 mRNA]; Acetylcysteine inhibits the reaction [bisphenol S results in decreased expression of CYP19A1 mRNA] |
CTD |
PMID:37944787 |
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NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO EXP |
[Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] which results in decreased expression of NQO1 mRNA; Acetylcysteine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Acetylcysteine inhibits the reaction [1-(4-chlorophenyl)-benzo-2,5-quinone results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA] [Acetylcysteine co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]; Acetylcysteine affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Acetylcysteine affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased activity of CYP1A1 protein]; Acetylcysteine inhibits the reaction [beta-Naphthoflavone results in decreased activity of CYP1A1 protein]; Acetylcysteine inhibits the reaction [chromium trioxide results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Acetylcysteine promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of CYP1A1 mRNA; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of CYP1A1 mRNA] Acetylcysteine results in increased expression of CYP1A1 protein |
CTD |
PMID:15044633 PMID:15621696 PMID:16274885 PMID:19033395 PMID:20801209 PMID:21094198 PMID:21703343 PMID:22129741 PMID:25668756 PMID:26535918 PMID:27041069 PMID:29753051 PMID:29975444 PMID:30639957 PMID:30793600 PMID:34171359 PMID:35123993 More...
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NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA] [CYP1A2 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite; Acetylcysteine inhibits the reaction [flutriafol results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:21424224 PMID:22129741 PMID:23159886 PMID:27989148 PMID:34200939 |
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NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA] Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:21703343 PMID:22129741 |
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NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
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G |
Cyp26c1 |
cytochrome P450, family 26, subfamily c, polypeptide 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CYP26C1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:37,673,560...37,681,774
Ensembl chr19:37,674,029...37,681,846
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G |
Cyp2a5 |
cytochrome P450, family 2, subfamily a, polypeptide 5 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2A5 protein] |
CTD |
PMID:22552773 |
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NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
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G |
Cyp2c38 |
cytochrome P450, family 2, subfamily c, polypeptide 38 |
multiple interactions |
ISO |
[CYP2C19 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite; Acetylcysteine inhibits the reaction [flutriafol results in increased expression of CYP2C19 mRNA] |
CTD |
PMID:27989148 PMID:34200939 |
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NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
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G |
Cyp2c65 |
cytochrome P450, family 2, subfamily c, polypeptide 65 |
multiple interactions |
ISO |
Acetylcysteine affects the reaction [CYP2C9 protein results in increased hydroxylation of bromfenac]; Acetylcysteine inhibits the reaction [flutriafol results in increased expression of CYP2C9 mRNA] |
CTD |
PMID:31815452 PMID:34200939 |
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NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
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Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
ISO EXP |
[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]; Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA] Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] Acetylcysteine inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [flutriafol results in increased expression of CYP2E1 mRNA] |
CTD |
PMID:21424224 PMID:23159886 PMID:26332274 PMID:30423402 PMID:34200939 PMID:35713687 More...
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NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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Cyp4a12b |
cytochrome P450, family 4, subfamily a, polypeptide 12B |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CYP4A1 mRNA; Acetylcysteine promotes the reaction [Bezafibrate results in increased expression of CYP4A1 mRNA] |
CTD |
PMID:19647067 PMID:22129741 |
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NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231
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G |
Cyp51 |
cytochrome P450, family 51 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [flutriafol results in increased expression of CYP51A1 mRNA] |
CTD |
PMID:34200939 |
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NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746
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G |
Dapk1 |
death associated protein kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of DAPK1 mRNA] |
CTD |
PMID:19477266 |
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NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005
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G |
Ddhd1 |
DDHD domain containing 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DDHD1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:45,830,628...45,895,600
Ensembl chr14:45,825,924...45,895,600
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions decreases expression |
ISO EXP |
Acetylcysteine results in increased expression of DDIT3 mRNA; Acetylcysteine results in increased expression of DDIT3 protein Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [dibromoacetonitrile results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Acetylcysteine promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 mRNA] 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [(4-methyl-1-naphthyl)-(1-pentylindol-3-yl)methanone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3]; Acetylcysteine inhibits the reaction [CSC-3436 results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [discretamine results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Ethylmercury Compounds results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [hesperetin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [ilimaquinone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [plumbagin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Quercetin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [rhododendrol results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [shogaol results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [shogaol results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tanshinone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Ursolic Acid results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased expression of DDIT3 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]] Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of DDIT3 protein] Acetylcysteine results in decreased expression of DDIT3 protein |
CTD |
PMID:16084531 PMID:17171638 PMID:18077580 PMID:18384088 PMID:19722195 PMID:20493918 PMID:21145380 PMID:21198628 PMID:21266191 PMID:21533816 PMID:21616140 PMID:23339468 PMID:24157283 PMID:24291486 PMID:24394546 PMID:24612139 PMID:24802810 PMID:24930757 PMID:25341683 PMID:25451595 PMID:25568320 PMID:25817893 PMID:25950987 PMID:26203587 PMID:26772155 PMID:26867644 PMID:27484784 PMID:27511942 PMID:27634458 PMID:27658547 PMID:27784618 PMID:27816613 PMID:28296042 PMID:28754437 PMID:29111403 PMID:30502353 PMID:30508555 PMID:31276663 PMID:31330229 PMID:32506763 PMID:32578922 PMID:32590070 PMID:34599545 PMID:35622622 PMID:36252918 PMID:37072049 PMID:37300854 PMID:37487865 PMID:38065397 More...
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NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [withaferin A results in increased expression of DDIT4 protein] |
CTD |
PMID:21266191 |
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NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
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G |
Defb12 |
defensin beta 12 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB12 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:19,161,947...19,164,850
Ensembl chr 8:19,161,947...19,164,866
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G |
Defb18 |
defensin beta 18 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB18 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:18,306,626...18,307,700
Ensembl chr 1:18,306,697...18,307,667
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G |
Defb3 |
defensin beta 3 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of DEFB4A mRNA |
CTD |
PMID:22385246 |
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NCBI chr 8:19,343,377...19,345,355
Ensembl chr 8:19,343,376...19,345,307
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of DGAT2 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of DGAT2 protein] |
CTD |
PMID:33007364 |
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NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
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G |
Dhfr |
dihydrofolate reductase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of DHFR mRNA] |
CTD |
PMID:36315628 |
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NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561
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G |
Dhh |
desert hedgehog |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DHH mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:98,779,496...98,796,443
Ensembl chr15:98,789,033...98,796,421
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G |
Dio2 |
deiodinase, iodothyronine, type II |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]] |
CTD |
PMID:18420745 |
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NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
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G |
Dio3 |
deiodinase, iodothyronine type III |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]] |
CTD |
PMID:18420745 |
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NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA] |
CTD |
PMID:28321046 |
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NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of DLG4 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of DLG4 protein] |
CTD |
PMID:27624276 PMID:28153600 |
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NCBI chr11:69,908,029...69,938,107
Ensembl chr11:69,907,768...69,938,348
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G |
Dmrt1 |
doublesex and mab-3 related transcription factor 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DMRT1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:25,483,070...25,581,692
Ensembl chr19:25,482,982...25,581,693
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G |
Dnah3 |
dynein, axonemal, heavy chain 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DNAH3 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 7:119,520,555...119,694,520
Ensembl chr 7:119,521,894...119,694,503
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G |
Dnai1 |
dynein axonemal intermediate chain 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DNAI1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:41,569,731...41,638,158
Ensembl chr 4:41,569,775...41,638,158
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of DNAJB1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of DNAJB4 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Acetylcysteine results in increased expression of DNAJB9 mRNA |
CTD |
PMID:16084531 |
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NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
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G |
Dnm1l |
dynamin 1-like |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [15-deoxyprostaglandin J2 affects the reaction [DNM1L protein binds to DNM1L protein binds to DNM1L protein binds to DNM1L protein]]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of DNM1L protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of DNM1L protein] Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate affects the localization of DNM1L protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the phosphorylation of DNM1L protein] Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of and results in increased phosphorylation of DNM1L protein] |
CTD |
PMID:20307494 PMID:30641872 PMID:31408635 PMID:37084995 PMID:37499777 |
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NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of DNMT1 mRNA; [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased methylation of DNMT1 promoter; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [DNMT1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of DNMT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DNMT1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DNMT1 protein] |
CTD |
PMID:29854080 PMID:31150806 PMID:31551408 |
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NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
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G |
Dnmt3b |
DNA methyltransferase 3B |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of DNMT3B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of DNMT3B protein] |
CTD |
PMID:26942697 PMID:31551408 |
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NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
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G |
Dsp |
desmoplakin |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dietary Fats results in increased expression of DSP mRNA] |
CTD |
PMID:21051528 |
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NCBI chr13:38,335,357...38,382,553
Ensembl chr13:38,335,270...38,382,553
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G |
Dspp |
dentin sialophosphoprotein |
increases expression |
ISO |
Acetylcysteine results in increased expression of DSPP mRNA |
CTD |
PMID:20951298 |
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NCBI chr 5:104,318,569...104,327,993
Ensembl chr 5:104,318,578...104,327,993
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G |
Dusp1 |
dual specificity phosphatase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DUSP1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DUSP1 protein] |
CTD |
PMID:18573614 |
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NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
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G |
Dusp4 |
dual specificity phosphatase 4 |
increases expression |
ISO |
Acetylcysteine results in increased expression of DUSP4 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 8:35,274,448...35,289,106
Ensembl chr 8:35,274,451...35,287,048
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G |
Dut |
deoxyuridine triphosphatase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [beta-hydroxyisovalerylshikonin results in decreased phosphorylation of and results in decreased activity of DUT protein] |
CTD |
PMID:18078828 |
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NCBI chr 2:125,089,168...125,100,969
Ensembl chr 2:125,089,110...125,100,528
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G |
E2f1 |
E2F transcription factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of E2F1 protein] |
CTD |
PMID:16497787 |
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NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
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G |
Edn1 |
endothelin 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased secretion of EDN1 protein] Acetylcysteine inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA] Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:14623829 PMID:16261333 PMID:21765237 |
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NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
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G |
Efcab3 |
EF-hand calcium binding domain 3 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EFCAB3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:104,576,533...105,008,365
Ensembl chr11:104,576,533...105,008,363
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G |
Efna1 |
ephrin A1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EFNA1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:89,179,037...89,188,258
Ensembl chr 3:89,179,040...89,188,449
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G |
Efnb2 |
ephrin B2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of EFNB2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242
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G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of EGF protein]; Acetylcysteine inhibits the reaction [cyadox results in increased expression of EGF]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA mRNA]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA protein] Acetylcysteine inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine]; Acetylcysteine inhibits the reaction [EGF protein results in increased abundance of Peroxides] |
CTD |
PMID:11158190 PMID:11214823 PMID:26138014 PMID:30265530 PMID:32092105 |
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NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of EGFR mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein] Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of EGFR protein] Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein] |
CTD |
PMID:10640773 PMID:14660655 PMID:15520183 PMID:15849355 PMID:16261333 PMID:17942915 PMID:21220312 PMID:23948867 PMID:26368632 PMID:26514923 PMID:28123000 More...
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NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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G |
Egln1 |
egl-9 family hypoxia-inducible factor 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of EGLN1 mRNA] |
CTD |
PMID:36315628 |
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NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063
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G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of EGR1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of EGR1 mRNA] Acetylcysteine inhibits the reaction [platycodin D results in increased expression of EGR1 mRNA] |
CTD |
PMID:10625299 PMID:18804340 PMID:19010381 |
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NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
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G |
Egr2 |
early growth response 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of EGR2 mRNA] |
CTD |
PMID:19350554 |
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NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
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G |
Ei24 |
etoposide induced 2.4 mRNA |
multiple interactions |
EXP |
Acetylcysteine promotes the reaction [Tobacco Smoke Pollution results in increased expression of EI24 mRNA] |
CTD |
PMID:16137721 |
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NCBI chr 9:36,690,449...36,708,630
Ensembl chr 9:36,690,455...36,708,689
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G |
Eif2a |
eukaryotic translation initiation factor 2A |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased phosphorylation of EIF2A protein]] Acetylcysteine inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [Cadmium results in decreased phosphorylation of EIF2A protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [bisphenol S results in increased phosphorylation of EIF2A protein] |
CTD |
PMID:21616140 PMID:25451595 PMID:27658547 PMID:29373603 PMID:37944787 PMID:38604440 More...
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NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2AK3 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [bisphenol S results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [chrysophanic acid results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pendulone results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine results in increased phosphorylation of and results in increased activity of EIF2AK3 protein Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [dibromoacetonitrile results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of EIF2AK3 protein] Acetylcysteine results in decreased expression of EIF2AK3 protein modified form Acetylcysteine inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2AK3 protein modified form] |
CTD |
PMID:19722195 PMID:25341683 PMID:25451595 PMID:27484784 PMID:27784618 PMID:30300626 PMID:31330229 PMID:32506763 PMID:35288263 PMID:37300854 PMID:37300869 PMID:37692514 PMID:37944787 PMID:38065397 PMID:38604440 More...
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NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
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G |
Eif2s1 |
eukaryotic translation initiation factor 2, subunit 1 alpha |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [chrysophanic acid results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of EIF2S1 protein] Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of EIF2S1 protein] Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2S1 protein modified form] |
CTD |
PMID:15788408 PMID:16324875 PMID:21911445 PMID:24291486 PMID:25568320 PMID:27484784 PMID:27634458 PMID:27709270 PMID:27816613 PMID:29380555 PMID:30300626 PMID:31330229 PMID:32506763 More...
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NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of EIF4EBP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased phosphorylation of EIF4EBP1 protein] Acetylcysteine inhibits the reaction [frenolicin B results in decreased phosphorylation of EIF4EBP1 protein] |
CTD |
PMID:21195169 PMID:24299490 PMID:26804764 PMID:30661989 PMID:36709824 |
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NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
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G |
Emilin2 |
elastin microfibril interfacer 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EMILIN2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr17:71,559,167...71,618,551
Ensembl chr17:71,559,167...71,618,973
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G |
Endog |
endonuclease G |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Acetylcysteine] affects the localization of ENDOG protein; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of ENDOG protein] |
CTD |
PMID:17309078 PMID:18034189 |
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NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081
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G |
Eng |
endoglin |
increases expression |
ISO |
Acetylcysteine results in increased expression of ENG mRNA; Acetylcysteine results in increased expression of ENG protein |
CTD |
PMID:32947957 |
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NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Toluene 2,4-Diisocyanate results in increased secretion of ENPP2 protein] |
CTD |
PMID:26072274 |
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NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
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G |
Enpp7 |
ectonucleotide pyrophosphatase/phosphodiesterase 7 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ENPP7 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:118,879,007...118,884,047
Ensembl chr11:118,879,014...118,884,047
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G |
Entrep1 |
endosomal transmembrane epsin interactor 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ENTREP1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:23,950,114...24,008,800
Ensembl chr19:23,950,114...24,008,383
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]] |
CTD |
PMID:19281832 |
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NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] |
CTD |
PMID:23958427 |
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NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
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G |
Epb41 |
erythrocyte membrane protein band 4.1 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in decreased expression of EPB41 protein] |
CTD |
PMID:20946910 |
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NCBI chr 4:131,650,724...131,802,824
Ensembl chr 4:131,650,724...131,802,632
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G |
Ephb1 |
Eph receptor B1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPHB1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:101,799,327...102,231,892
Ensembl chr 9:101,799,327...102,231,892
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G |
Eps8 |
epidermal growth factor receptor pathway substrate 8 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPS8 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 6:137,454,242...137,626,262
Ensembl chr 6:137,454,243...137,631,874
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G |
Ercc1 |
excision repair cross-complementing rodent repair deficiency, complementation group 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of ERCC1 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449
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G |
Ercc8 |
excision repaiross-complementing rodent repair deficiency, complementation group 8 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [dicrotophos results in decreased expression of ERCC8 protein] |
CTD |
PMID:28302478 |
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NCBI chr13:108,295,246...108,337,738
Ensembl chr13:108,295,265...108,331,898
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G |
Ern1 |
endoplasmic reticulum to nucleus signalling 1 |
multiple interactions decreases phosphorylation |
ISO EXP |
Acetylcysteine inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ERN1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased phosphorylation of ERN1 protein] Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]] Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ERN1 protein modified form]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of ERN1 protein] Acetylcysteine results in decreased phosphorylation of ERN1 protein |
CTD |
PMID:21198628 PMID:24394546 PMID:25451595 PMID:27784618 PMID:29373603 PMID:30633982 PMID:31330229 PMID:34687772 PMID:37692514 PMID:38604440 More...
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NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
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G |
Esr1 |
estrogen receptor 1 (alpha) |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of ESR1 protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR1 mRNA] Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ESR1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of ESR1 protein] |
CTD |
PMID:18829485 PMID:26149760 PMID:32402895 PMID:39260547 |
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Esr2 |
estrogen receptor 2 (beta) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR2 mRNA] |
CTD |
PMID:18829485 |
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NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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G |
Esrra |
estrogen related receptor, alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESRRA protein] |
CTD |
PMID:30104959 |
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NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208
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G |
Ets1 |
E26 avian leukemia oncogene 1, 5' domain |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of ETS1 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of ETS1 mRNA]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA] |
CTD |
PMID:21635667 |
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NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [EZH2 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of EZH2 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of EZH2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of EZH2 protein] |
CTD |
PMID:24582688 PMID:31551408 |
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NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275
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G |
F13a1 |
coagulation factor XIII, A1 subunit |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of F13A1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
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G |
F3 |
coagulation factor III |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA] |
CTD |
PMID:23114885 |
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NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
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G |
Fabp4 |
fatty acid binding protein 4, adipocyte |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of FABP4 protein] |
CTD |
PMID:27117918 |
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NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
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G |
Fadd |
Fas associated via death domain |
multiple interactions |
ISO EXP |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of FADD protein] [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of FADD mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of FADD protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of FADD mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of FADD protein]] |
CTD |
PMID:20946910 PMID:35833596 |
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NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
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G |
Fads2 |
fatty acid desaturase 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FADS2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110
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G |
Fam114a1 |
family with sequence similarity 114, member A1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:65,127,459...65,199,217
Ensembl chr 5:65,127,414...65,199,229
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G |
Fam114a2 |
family with sequence similarity 114, member A2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:57,373,816...57,409,482
Ensembl chr11:57,373,819...57,409,443
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G |
Fam13a |
family with sequence similarity 13, member A |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM13A mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:58,910,521...59,001,487
Ensembl chr 6:58,909,075...59,001,534
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G |
Fam186a |
family with sequence similarity 186, member A |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM186A mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:99,816,226...99,864,974
Ensembl chr15:99,816,229...99,864,942
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G |
Far1 |
fatty acyl CoA reductase 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAR1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:113,113,008...113,170,713
Ensembl chr 7:113,113,041...113,170,718
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of FAS mRNA] Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of FAS protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of FAS protein] Acetylcysteine results in increased expression of FAS mRNA |
CTD |
PMID:9227460 PMID:15382040 PMID:16169029 PMID:19014919 PMID:19477266 PMID:19720122 PMID:21741372 PMID:28219700 More...
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NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
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G |
Fasl |
Fas ligand |
multiple interactions increases expression |
ISO EXP |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of FASLG mRNA; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased expression of FASLG protein] Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of FASLG protein] [Atorvastatin co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein] Acetylcysteine results in increased expression of FASLG mRNA |
CTD |
PMID:11864783 PMID:17574045 PMID:19644561 PMID:19720122 PMID:19760616 PMID:20431929 PMID:20946910 PMID:22429591 PMID:26332274 PMID:28219700 More...
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NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
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G |
Fbxo32 |
F-box protein 32 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Indican results in increased expression of FBXO32 protein] |
CTD |
PMID:30849338 |
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NCBI chr15:58,039,275...58,078,288
Ensembl chr15:58,039,275...58,078,328
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G |
Fen1 |
flap structure specific endonuclease 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of FEN1 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533
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G |
Fer1l5 |
fer-1 like family member 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FER1L5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:36,411,264...36,461,191
Ensembl chr 1:36,411,372...36,461,191
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G |
Fgf12 |
fibroblast growth factor 12 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FGF12 mRNA |
CTD |
PMID:22129741 |
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NCBI chr16:27,976,535...28,571,995
Ensembl chr16:27,978,850...28,571,820
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G |
Fgf2 |
fibroblast growth factor 2 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of FGF2 mRNA Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in increased secretion of FGF2 protein] |
CTD |
PMID:16084531 PMID:19176594 |
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NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FGF21 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of FGF21 mRNA] Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of FGF21 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased secretion of FGF21 protein] |
CTD |
PMID:22129741 PMID:22917661 |
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NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
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G |
Fgf6 |
fibroblast growth factor 6 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FGF6 protein] |
CTD |
PMID:26138014 |
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NCBI chr 6:126,992,505...127,001,681
Ensembl chr 6:126,992,549...127,005,150
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G |
Fgf7 |
fibroblast growth factor 7 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FGF7 protein] |
CTD |
PMID:26138014 |
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NCBI chr 2:125,876,578...125,933,105
Ensembl chr 2:125,876,578...125,933,105
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G |
Fhit |
fragile histidine triad gene |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of FHIT protein] |
CTD |
PMID:16585223 |
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NCBI chr14:11,307,718...12,919,681
Ensembl chr14:11,307,738...12,919,681
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G |
Filip1l |
filamin A interacting protein 1-like |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of FILIP1L mRNA |
CTD |
PMID:16084531 |
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NCBI chr16:57,173,376...57,393,167
Ensembl chr16:57,173,456...57,393,489
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of FIS1 protein] Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of FIS1 protein] |
CTD |
PMID:37084995 PMID:37499777 |
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NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
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G |
Fkbp5 |
FK506 binding protein 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of FKBP5 mRNA] |
CTD |
PMID:18829485 |
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NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
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G |
Flg |
filaggrin |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FLG mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993
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G |
Flna |
filamin, alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of FLNA protein] |
CTD |
PMID:25944616 |
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NCBI chr X:73,267,067...73,293,787
Ensembl chr X:73,267,067...73,293,426
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G |
Flt1 |
FMS-like tyrosine kinase 1 |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of FLT1 protein Acetylcysteine inhibits the reaction [Cadmium results in increased expression of FLT1 mRNA]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of FLT1 mRNA] |
CTD |
PMID:17992120 PMID:29408318 |
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NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
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G |
Flt3l |
FMS-like tyrosine kinase 3 ligand |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FLT3LG protein] |
CTD |
PMID:26138014 |
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NCBI chr 7:44,780,607...44,785,914
Ensembl chr 7:44,779,212...44,785,856
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G |
Fmr1 |
fragile X messenger ribonucleoprotein 1 |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] |
CTD |
PMID:27385396 |
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NCBI chr X:67,722,144...67,761,569
Ensembl chr X:67,722,147...67,761,569
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G |
Fn1 |
fibronectin 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Glucose results in increased expression of FN1 protein] Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP10 protein]; Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP13 protein]; Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP3 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of FN1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of FN1 mRNA] |
CTD |
PMID:16632126 PMID:17395008 PMID:22245600 PMID:22648416 |
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NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
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G |
Fos |
FBJ osteosarcoma oncogene |
multiple interactions decreases activity |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOS]; Acetylcysteine inhibits the reaction [Etoposide results in increased expression of FOS]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased activity of FOS protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of FOS] Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [oxaliplatin results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [FOS protein co-treated with JUN protein]]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of FOS mRNA] Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in decreased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Carbon Tetrachloride results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of and results in increased phosphorylation of FOS protein]; Acetylcysteine promotes the reaction [bis(maltolato)oxovanadium(IV) results in decreased activity of [FOS protein binds to JUN protein]] Acetylcysteine results in decreased activity of FOS protein |
CTD |
PMID:7743507 PMID:8825185 PMID:8853906 PMID:9043100 PMID:9525474 PMID:10692565 PMID:14623829 PMID:15520183 PMID:16137721 PMID:17696279 PMID:19654923 PMID:20654705 PMID:22129741 PMID:23824011 PMID:24908156 PMID:36813253 More...
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NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
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G |
Fosl1 |
fos-like antigen 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOSL1 mRNA] |
CTD |
PMID:15520183 PMID:19010381 |
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NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
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G |
Foxd2 |
forkhead box D2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:114,763,477...114,766,095
Ensembl chr 4:114,763,479...114,766,070
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G |
Foxd4 |
forkhead box D4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:24,876,307...24,878,380
Ensembl chr19:24,876,600...24,878,561
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G |
Foxm1 |
forkhead box M1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Thiostrepton results in decreased expression of FOXM1 protein] |
CTD |
PMID:22761781 |
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NCBI chr 6:128,339,957...128,352,849
Ensembl chr 6:128,339,930...128,353,109
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cyclosporine results in increased expression of and affects the localization of FOXO1 protein modified form]; Acetylcysteine inhibits the reaction [Glucose affects the localization of FOXO1 protein] |
CTD |
PMID:23765110 PMID:33450223 |
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NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
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G |
Foxo3 |
forkhead box O3 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Simvastatin results in increased phosphorylation of FOXO3 protein] Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of FOXO3 protein] Acetylcysteine inhibits the reaction [tomentosin results in increased expression of FOXO3 protein] |
CTD |
PMID:20883752 PMID:23159718 PMID:25471227 PMID:30104959 PMID:30917517 PMID:34358621 More...
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NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
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G |
Foxp3 |
forkhead box P3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of FOXP3 protein] |
CTD |
PMID:31900833 |
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NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484
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G |
Fshb |
follicle stimulating hormone beta |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of FSHB protein] |
CTD |
PMID:30633982 |
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NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
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G |
Fth1 |
ferritin heavy polypeptide 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Rotenone results in increased expression of FTH1 mRNA] Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of FTH1 protein] |
CTD |
PMID:18325346 PMID:32687844 |
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NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
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G |
Ftl1 |
ferritin light polypeptide 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenite results in increased expression of FTL1 protein] |
CTD |
PMID:15175009 |
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NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
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G |
Fto |
FTO alpha-ketoglutarate dependent dioxygenase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of FTO mRNA] Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of FTO mRNA] |
CTD |
PMID:31004932 PMID:34425375 |
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NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067
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G |
Fxn |
frataxin |
affects response to substance multiple interactions |
EXP ISO |
Acetylcysteine affects the susceptibility to FXN protein mutant form Acetylcysteine affects the reaction [Ethanol affects the expression of FXN protein] |
CTD |
PMID:16120311 PMID:33017621 |
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NCBI chr19:24,236,909...24,257,954
Ensembl chr19:24,238,817...24,257,969
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G |
Fyn |
Fyn proto-oncogene |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of FYN protein] Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of FYN protein] |
CTD |
PMID:12902192 PMID:20850416 |
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NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of G6PC1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
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G |
G6pdx |
glucose-6-phosphate dehydrogenase X-linked |
multiple interactions increases activity |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA] Acetylcysteine results in increased activity of G6PD protein |
CTD |
PMID:3099627 PMID:12717738 PMID:15225644 |
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NCBI chr X:73,453,089...73,472,486
Ensembl chr X:73,453,089...73,472,800
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G |
Gadd45a |
growth arrest and DNA-damage-inducible 45 alpha |
multiple interactions increases expression decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Formaldehyde results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [rhododendrol results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of GADD45A mRNA] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GADD45A mRNA; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GADD45A mRNA] Acetylcysteine results in increased expression of GADD45A mRNA Acetylcysteine results in decreased expression of GADD45A mRNA |
CTD |
PMID:18849615 PMID:22129741 PMID:24291486 PMID:26332274 PMID:26867644 |
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NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
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G |
Gadd45g |
growth arrest and DNA-damage-inducible 45 gamma |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GADD45G mRNA Acetylcysteine inhibits the reaction [[xanthatin results in increased expression of GADD45G mRNA] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of GADD45G mRNA]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of GADD45G protein] |
CTD |
PMID:22129741 PMID:23313378 |
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NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504
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G |
Galntl5 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GALNTL5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:25,386,438...25,425,295
Ensembl chr 5:25,386,458...25,425,295
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G |
Gap43 |
growth associated protein 43 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of GAP43 protein] |
CTD |
PMID:18375950 |
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NCBI chr16:42,068,915...42,161,014
Ensembl chr16:42,068,805...42,161,014
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [arsenite results in decreased expression of GAPDH protein] Acetylcysteine results in decreased expression of GAPDH mRNA |
CTD |
PMID:11108245 PMID:15175009 |
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NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
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G |
Gata1 |
GATA binding protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
CTD |
PMID:10656287 |
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NCBI chr X:7,825,504...7,842,844
Ensembl chr X:7,825,499...7,844,310
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G |
Gbp2b |
guanylate binding protein 2b |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of GBP1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 3:142,300,577...142,324,940
Ensembl chr 3:142,300,608...142,324,940
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Hydrocarbons, Chlorinated analog results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Indomethacin results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Sulindac results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of GCLC mRNA] Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA] Acetylcysteine inhibits the reaction [decamethrin results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of GCLC protein] |
CTD |
PMID:11820781 PMID:11909699 PMID:16631525 PMID:17540521 PMID:17980396 PMID:19328227 PMID:20851755 PMID:21728338 PMID:24355586 PMID:25263748 PMID:30951941 PMID:31029725 PMID:34036678 PMID:35123994 PMID:37598316 More...
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NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
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G |
Gclm |
glutamate-cysteine ligase, modifier subunit |
multiple interactions affects response to substance |
ISO EXP |
Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of GCLM mRNA]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of GCLM mRNA] [Acetylcysteine co-treated with Acetaminophen] results in decreased expression of GCLM mRNA; Acetylcysteine inhibits the reaction [arsenite results in increased expression of GCLM mRNA] GCLM protein affects the susceptibility to Acetylcysteine |
CTD |
PMID:17584759 PMID:18723479 PMID:19328227 PMID:19350554 PMID:37598316 |
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NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
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G |
Gdf1 |
growth differentiation factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of GDF1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of GDF1 protein] |
CTD |
PMID:33360347 |
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NCBI chr 8:70,768,425...70,784,242
Ensembl chr 8:70,768,425...70,784,242 Ensembl chr 8:70,768,425...70,784,242
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G |
Gdf15 |
growth differentiation factor 15 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GDF15 mRNA] |
CTD |
PMID:35123994 |
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NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
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G |
Gdnf |
glial cell line derived neurotrophic factor |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GDNF mRNA Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of GDNF protein] |
CTD |
PMID:22129741 PMID:26138014 |
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NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
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G |
Gfap |
glial fibrillary acidic protein |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein] Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of GFAP protein] |
CTD |
PMID:28499986 PMID:31173782 |
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NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GGT1 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased secretion of GGT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]; Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GGT1 protein]; Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of GGT1 protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]] |
CTD |
PMID:12030384 PMID:22129741 PMID:24485406 PMID:24634002 PMID:27387968 |
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NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of GJA1 protein] [Acetylcysteine co-treated with ascorbate-2-phosphate] affects the expression of GJA1 mRNA; [Fulvestrant co-treated with U 0126] affects the reaction [[Acetylcysteine co-treated with ascorbate-2-phosphate] affects the expression of GJA1 mRNA]; Acetylcysteine inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of GJA1 protein]; bisphenol A affects the reaction [[Acetylcysteine co-treated with ascorbate-2-phosphate] affects the expression of GJA1 mRNA]; Fulvestrant affects the reaction [[Acetylcysteine co-treated with ascorbate-2-phosphate] affects the expression of GJA1 mRNA]; U 0126 affects the reaction [[Acetylcysteine co-treated with ascorbate-2-phosphate] affects the expression of GJA1 mRNA] |
CTD |
PMID:32610363 PMID:34906888 PMID:37692924 |
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NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
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G |
Gja4 |
gap junction protein, alpha 4 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of GJA4 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 4:127,205,213...127,207,832
Ensembl chr 4:127,205,214...127,207,832
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G |
Gjb1 |
gap junction protein, beta 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of GJB1 mRNA] |
CTD |
PMID:32142722 |
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NCBI chr X:100,419,982...100,429,235
Ensembl chr X:100,419,984...100,429,235
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G |
Gk |
glycerol kinase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Malathion results in increased activity of GK protein] |
CTD |
PMID:25449180 |
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NCBI chr X:84,745,543...84,820,425
Ensembl chr X:84,745,543...84,820,425
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G |
Gkn2 |
gastrokine 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GKN2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:87,350,347...87,356,476
Ensembl chr 6:87,350,339...87,356,479
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G |
Glb1 |
galactosidase, beta 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased activity of GLB1 protein]; Acetylcysteine inhibits the reaction [lopinavir-ritonavir drug combination results in increased activity of GLB1 protein]; Acetylcysteine inhibits the reaction [Ritonavir results in increased activity of GLB1 protein] |
CTD |
PMID:20884875 PMID:31551408 |
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NCBI chr 9:114,230,146...114,303,447
Ensembl chr 9:114,230,144...114,303,966
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G |
Glcci1 |
glucocorticoid induced transcript 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GLCCI1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:8,509,600...8,597,549
Ensembl chr 6:8,509,600...8,597,548
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein] |
CTD |
PMID:22925809 |
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NCBI chr17:31,120,841...31,155,484
Ensembl chr17:31,120,791...31,159,765
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G |
Glrx |
glutaredoxin |
affects response to substance |
ISO |
GLRX protein affects the susceptibility to Acetylcysteine |
CTD |
PMID:17468103 |
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NCBI chr13:75,988,004...75,998,270
Ensembl chr13:75,987,987...75,998,273
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of GLUD1 mRNA] |
CTD |
PMID:31857147 |
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NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222
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G |
Gnai2 |
G protein subunit alpha i2 |
multiple interactions |
EXP ISO |
Acetylcysteine affects the reaction [IER3 protein affects the expression of GNAI2 mRNA] Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein] |
CTD |
PMID:18441196 PMID:20713914 |
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NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
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G |
Gnai3 |
G protein subunit alpha i3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] |
CTD |
PMID:18441196 |
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NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462
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G |
Got1 |
glutamic-oxaloacetic transaminase 1, soluble |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GOT1 protein] |
CTD |
PMID:27387968 |
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NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
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G |
Gp1ba |
glycoprotein 1b, alpha polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [THPO protein results in increased expression of GP1BA protein] |
CTD |
PMID:20523355 |
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NCBI chr11:70,529,928...70,534,812
Ensembl chr11:70,529,948...70,532,862
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G |
Gp2 |
glycoprotein 2 zymogen granule membrane |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GP2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:119,041,760...119,058,495
Ensembl chr 7:119,041,760...119,058,508
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G |
Gpbar1 |
G protein-coupled bile acid receptor 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPBAR1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:74,316,269...74,318,868
Ensembl chr 1:74,317,709...74,318,783
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G |
Gpc5 |
glypican 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPC5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPC5 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr14:115,329,640...116,762,604
Ensembl chr14:115,329,647...116,762,591
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G |
Gpr153 |
G protein-coupled receptor 153 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR153 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:152,358,563...152,369,798
Ensembl chr 4:152,358,689...152,369,794
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G |
Gpr20 |
G protein-coupled receptor 20 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR20 mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:73,560,346...73,579,354
Ensembl chr15:73,566,453...73,579,354
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G |
Gpr55 |
G protein-coupled receptor 55 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR55 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPR55 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 1:85,860,927...85,924,781
Ensembl chr 1:85,866,039...85,888,729
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G |
Gpt |
glutamic pyruvic transaminase, soluble |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [PTEN gene mutant form results in increased secretion of GPT protein]]; IL22 protein promotes the reaction [Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GPT protein]] [Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen affects the activity of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Cyclosporine results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Glyphosate results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GPT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]] |
CTD |
PMID:17461432 PMID:20688495 PMID:20804811 PMID:23375450 PMID:24485406 PMID:27022031 PMID:27387968 PMID:27720869 PMID:28435131 PMID:28887131 PMID:29704510 PMID:30423402 PMID:30641872 PMID:32402895 PMID:33797725 PMID:33882750 PMID:37458150 PMID:37598316 PMID:37860953 PMID:38042273 More...
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NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA] Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased expression of GPX1 mRNA]; Acetylcysteine inhibits the reaction [raspberry ketone results in decreased expression of GPX1 protein]; Acetylcysteine inhibits the reaction [rhododendrol results in decreased expression of GPX1 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in decreased expression of GPX1 mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in decreased expression of GPX1 protein] Acetylcysteine results in increased expression of GPX1 protein Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of GPX1 protein] |
CTD |
PMID:25341683 PMID:26867644 PMID:30037311 PMID:30104959 PMID:35112789 PMID:39362619 More...
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NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
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G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Antimony results in decreased expression of GPX4 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of GPX4 mRNA] |
CTD |
PMID:12208374 PMID:38097005 |
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NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
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G |
Grin2b |
glutamate receptor, ionotropic, NMDA2B (epsilon 2) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Pilocarpine results in increased expression of GRIN2B protein] |
CTD |
PMID:22824136 |
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NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
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G |
Grm2 |
glutamate receptor, metabotropic 2 |
increases activity |
ISO |
Acetylcysteine results in increased activity of GRM2 protein |
CTD |
PMID:19136971 |
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NCBI chr 9:106,521,733...106,533,308
Ensembl chr 9:106,520,294...106,533,281
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G |
Grm3 |
glutamate receptor, metabotropic 3 |
increases activity |
ISO |
Acetylcysteine results in increased activity of GRM3 protein |
CTD |
PMID:19136971 |
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NCBI chr 5:9,535,235...9,776,087
Ensembl chr 5:9,535,541...9,775,170
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G |
Grm5 |
glutamate receptor, metabotropic 5 |
increases activity |
ISO |
Acetylcysteine results in increased activity of GRM5 protein |
CTD |
PMID:19136971 |
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NCBI chr 7:87,233,212...87,784,271
Ensembl chr 7:87,233,376...87,784,115
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G |
Gsdmd |
gasdermin D |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine affects the reaction [diallyl trisulfide results in increased expression of and results in increased cleavage of GSDMD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]; Acetylcysteine inhibits the reaction [piperlongumine results in increased expression of GSDMD protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased cleavage of GSDMD protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of GSDMD protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]] Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD protein]; Acetylcysteine inhibits the reaction [Atrazine results in increased expression of GSDMD protein] Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of GSDMD protein] Acetylcysteine results in increased expression of GSDMD protein |
CTD |
PMID:30378427 PMID:34791735 PMID:36347317 PMID:36354081 PMID:36646296 PMID:37393521 PMID:38242274 PMID:38301994 PMID:38821455 More...
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NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
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G |
Gsdme |
gasdermin E |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of GSDME protein] |
CTD |
PMID:36801614 |
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NCBI chr 6:50,167,013...50,240,837
Ensembl chr 6:50,165,868...50,240,842
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of GSK3B protein] [Acetylcysteine co-treated with Chlorpyrifos] results in increased activity of GSK3B protein; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:18569013 PMID:19126599 PMID:24968063 PMID:25246272 PMID:27658547 PMID:33131013 PMID:33930485 More...
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NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
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G |
Gsr |
glutathione reductase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of GSR mRNA]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in decreased expression of GSR mRNA] [Acetylcysteine co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein; [Acetylcysteine co-treated with Paraquat] results in increased activity of GSR protein; Acetylcysteine inhibits the reaction [arsenic trioxide inhibits the reaction [GSR protein results in increased oxidation of NADP]]; Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of GSR mRNA]; Acetylcysteine inhibits the reaction [Dimethylnitrosamine results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of GSR protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [EUK-134 results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]] Acetylcysteine inhibits the reaction [Acetaminophen results in decreased activity of GSR protein] |
CTD |
PMID:16631525 PMID:19840221 PMID:21114986 PMID:23159886 PMID:24634002 PMID:25724285 PMID:26079211 PMID:30951941 PMID:37458150 More...
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NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
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G |
Gsta1 |
glutathione S-transferase, alpha 1 (Ya) |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTA5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
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G |
Gsta4 |
glutathione S-transferase, alpha 4 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with EUK-134] promotes the reaction [[Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Paraquat results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Zinc Sulfate results in increased activity of GSTA4 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Maneb results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Maneb results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA] |
CTD |
PMID:23159886 PMID:25724285 PMID:30639957 |
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NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631
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G |
Gstm1 |
glutathione S-transferase, mu 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA |
CTD |
PMID:21871945 PMID:22129741 |
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NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
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G |
Gstm2 |
glutathione S-transferase, mu 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
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G |
Gsto2 |
glutathione S-transferase omega 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [flutriafol results in increased expression of GSTO2 mRNA] |
CTD |
PMID:34200939 |
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NCBI chr19:47,853,879...47,874,747
Ensembl chr19:47,853,973...47,874,763
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G |
Gstp1 |
glutathione S-transferase, pi 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTP1 mRNA] Acetylcysteine inhibits the reaction [flutriafol results in increased expression of GSTP1 mRNA] |
CTD |
PMID:22129741 PMID:34200939 |
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NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
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G |
Gulp1 |
GULP, engulfment adaptor PTB domain containing 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of GULP1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 1:44,590,540...44,835,998
Ensembl chr 1:44,590,671...44,835,998
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G |
Gypa |
glycophorin A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] |
CTD |
PMID:20523355 |
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NCBI chr 8:81,220,674...81,237,414
Ensembl chr 8:81,220,410...81,237,171
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G |
H2ax |
H2A.X variant histone |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [4-biphenylamine results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl)imidazole results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [[fludarabine co-treated with LAQ824] results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [alpha-terthienylmethanol results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [captax results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [chloropicrin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [Crizotinib results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [eprenetapopt results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [gingerenone A results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [LAQ824 results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [manumycin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [PCB 180 metabolite results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [phenanthridone results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [Plant Extracts results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [polyhexamethyleneguanidine results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased expression of H2AX protein] Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of H2AX mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased activity of H2AX protein] Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [aristolochic acid I results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [yttrium chloride results in increased phosphorylation of H2AX protein] Acetylcysteine results in increased expression of H2AX protein |
CTD |
PMID:15173094 PMID:15489221 PMID:18852132 PMID:19409983 PMID:21135414 PMID:22172632 PMID:23274516 PMID:24614525 PMID:25633853 PMID:26079211 PMID:26148434 PMID:28300663 PMID:28506552 PMID:28993908 PMID:29128613 PMID:29416738 PMID:30408460 PMID:30917517 PMID:31157515 PMID:31168028 PMID:31639374 PMID:31682804 PMID:31715134 PMID:31884112 PMID:32433928 PMID:33031904 PMID:33961949 PMID:33971260 PMID:35088107 PMID:35123993 PMID:35279910 PMID:35326237 PMID:36863539 PMID:37072049 PMID:39362619 More...
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NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
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G |
Has2 |
hyaluronan synthase 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA] |
CTD |
PMID:21220312 |
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NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 protein] Acetylcysteine inhibits the reaction [Antimony results in increased expression of HAVCR1 protein] |
CTD |
PMID:35020164 PMID:38097005 |
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NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
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G |
Hax1 |
HCLS1 associated X-1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of HAX1 protein] |
CTD |
PMID:19679660 |
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NCBI chr 3:89,902,753...89,906,023
Ensembl chr 3:89,902,753...89,906,087
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [vanadium pentoxide results in increased expression of HBEGF mRNA] |
CTD |
PMID:12676768 |
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NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
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G |
Hc |
hemolytic complement |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C5 protein] |
CTD |
PMID:32924446 |
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NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450
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G |
Hectd4 |
HECT domain E3 ubiquitin protein ligase 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Ethanol results in increased expression of HECTD4 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of HECTD4 mRNA] |
CTD |
PMID:31004932 PMID:35713687 |
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NCBI chr 5:121,357,323...121,506,633
Ensembl chr 5:121,358,282...121,506,640
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G |
Herpud1 |
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of HERPUD1 mRNA Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HERPUD1 mRNA] |
CTD |
PMID:16084531 PMID:18723479 |
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NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
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G |
Hes1 |
hes family bHLH transcription factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cypermethrin results in decreased expression of HES1 mRNA] |
CTD |
PMID:38582279 |
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NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
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G |
Hey2 |
hairy/enhancer-of-split related with YRPW motif 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cypermethrin results in decreased expression of HEY2 mRNA] |
CTD |
PMID:38582279 |
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NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797
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G |
Hgf |
hepatocyte growth factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of HGF protein] |
CTD |
PMID:16757516 |
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NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
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G |
Hhip |
Hedgehog-interacting protein |
multiple interactions |
ISO |
[Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of HHIP mRNA |
CTD |
PMID:21051528 |
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NCBI chr 8:80,692,480...80,784,637
Ensembl chr 8:80,692,480...80,784,635
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G |
Hif1a |
hypoxia inducible factor 1, alpha subunit |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein] 1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Cisplatin affects the localization of HIF1A protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of HIF1A mRNA]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]] Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Nickel analog results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]] |
CTD |
PMID:10866824 PMID:11641398 PMID:11886167 PMID:13679210 PMID:16530163 PMID:17015263 PMID:17066447 PMID:17658243 PMID:19374849 PMID:19410601 PMID:21036805 PMID:22648416 PMID:22700867 PMID:25406100 PMID:27297870 PMID:29408318 PMID:31850806 PMID:35430258 PMID:36709824 PMID:36739042 More...
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NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
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G |
Hk2 |
hexokinase 2 |
increases expression multiple interactions |
ISO EXP |
Acetylcysteine results in increased expression of HK2 mRNA Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of HK2 protein]] |
CTD |
PMID:16084531 PMID:36762617 |
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NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435
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G |
Hmbs |
hydroxymethylbilane synthase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
CTD |
PMID:10656287 |
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NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
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G |
Hmga2 |
high mobility group AT-hook 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMGA2 protein] |
CTD |
PMID:27071802 |
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NCBI chr10:120,197,173...120,312,374
Ensembl chr10:120,197,180...120,312,374
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HMGB1 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of HMGB1 protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein] |
CTD |
PMID:26079697 PMID:30977640 PMID:36055550 |
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NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
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G |
Hmgb2 |
high mobility group box 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of HMGB2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:57,964,877...57,969,033
Ensembl chr 8:57,964,941...57,969,033
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-Coenzyme A reductase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR mRNA] |
CTD |
PMID:19931295 |
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NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
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G |
Hmox1 |
heme oxygenase 1 |
increases expression affects activity multiple interactions |
EXP ISO |
Acetylcysteine results in increased expression of HMOX1 protein Acetylcysteine results in increased expression of HMOX1 mRNA; Acetylcysteine results in increased expression of HMOX1 protein Acetylcysteine affects the activity of HMOX1 protein Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [2,2'-dihydroxychalcone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide results in increased abundance of Peroxides] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[chromium trioxide co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Curcumin co-treated with piperine] results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid results in increased abundance of Peroxides] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [carnosol results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [chromium trioxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal results in increased expression of HMOX1]; Acetylcysteine inhibits the reaction [Hemin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 protein]]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Quercetin analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Urea results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein]; Polymyxin B inhibits the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 mRNA]] [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; Acetylcysteine affects the reaction [Glucose affects the expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Oxidopamine results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [oxophenylarsine results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein] [Acetylcysteine results in increased abundance of Glutathione] inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine affects the reaction [alpha-pyrrolidinononanophenone analog affects the expression of HMOX1 protein]; Acetylcysteine affects the reaction [Chlorpyrifos affects the expression of HMOX1 protein]; Acetylcysteine affects the reaction [Pyruvaldehyde affects the expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-butenal results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-xylene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of arsenite] which results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[tin protoporphyrin IX results in decreased activity of HMOX1 protein] which results in increased chemical synthesis of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Ammonium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Benzene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [chloropicrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Coal Ash results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [gallium nitrate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [lead acetate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of HMOX1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Polychlorinated Biphenyls analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ritonavir results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ritonavir results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Silicon analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Silver analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [tetrathiomolybdate analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Toluene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Oxygen results in increased expression of HMOX1 mRNA] |
CTD |
PMID:7538129 PMID:9152014 PMID:9545559 PMID:9747510 PMID:10975858 PMID:11103787 PMID:11592956 PMID:12420312 PMID:12690112 PMID:12699905 PMID:12763371 PMID:14687664 PMID:15175009 PMID:15368090 PMID:15541757 PMID:16137721 PMID:16171798 PMID:16274885 PMID:16631525 PMID:16806455 PMID:16890772 PMID:16959797 PMID:17540521 PMID:17979524 PMID:18077580 PMID:18156441 PMID:18332044 PMID:18336854 PMID:18357586 PMID:18586083 PMID:18723479 PMID:18830972 PMID:19033392 PMID:19136476 PMID:19323979 PMID:19350554 PMID:19642688 PMID:19654923 PMID:20020861 PMID:20054154 PMID:20934533 PMID:20938987 PMID:21144877 PMID:21238556 PMID:21384399 PMID:21397656 PMID:21626191 PMID:21787718 PMID:22019695 PMID:22263782 PMID:22507881 PMID:22564156 PMID:22643931 PMID:22659318 PMID:22714038 PMID:22917016 PMID:23290930 PMID:23900960 PMID:23942037 PMID:24126012 PMID:24291486 PMID:24355171 PMID:24361488 PMID:24401988 PMID:24489685 PMID:25003661 PMID:25246272 PMID:26163453 PMID:26169828 PMID:26291278 PMID:26404762 PMID:26542248 PMID:26600472 PMID:26658076 PMID:26945724 PMID:26968795 PMID:27151894 PMID:27393915 PMID:27658547 PMID:27725188 PMID:27777014 PMID:27867098 PMID:28013216 PMID:28555929 PMID:29086419 PMID:29111403 PMID:29155359 PMID:29540228 PMID:30104959 PMID:30349652 PMID:30633982 PMID:30951941 PMID:30965051 PMID:31029725 PMID:31272005 PMID:31790703 PMID:31884112 PMID:32023790 PMID:32525552 PMID:32708634 PMID:33930485 PMID:34036678 PMID:35123994 PMID:36813253 PMID:37084995 PMID:37353053 PMID:37369159 PMID:37598316 PMID:37598416 PMID:37692514 PMID:38040126 PMID:38513841 PMID:39362619 More...
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NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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G |
Hnf4g |
hepatocyte nuclear factor 4, gamma |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of HNF4G mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:3,573,090...3,724,863
Ensembl chr 3:3,573,084...3,724,860
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G |
Hras |
Harvey rat sarcoma virus oncogene |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of HRAS mRNA] Acetylcysteine inhibits the reaction [HRAS protein mutant form results in increased susceptibility to sodium arsenite] |
CTD |
PMID:15945272 PMID:25199681 |
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NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
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G |
Hsbp1 |
heat shock factor binding protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Thioacetamide results in increased expression of HSBP1 protein] |
CTD |
PMID:17103249 |
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NCBI chr 8:120,071,277...120,075,668
Ensembl chr 8:120,071,227...120,075,661
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G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD11B2 mRNA] |
CTD |
PMID:18829485 |
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NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620
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G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of HSD17B3 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA] |
CTD |
PMID:26769589 PMID:29567110 |
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NCBI chr13:64,206,088...64,237,076
Ensembl chr13:64,206,080...64,237,044
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G |
Hsd17b8 |
hydroxysteroid 17-beta dehydrogenase 8 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD17B8 mRNA] |
CTD |
PMID:18829485 |
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NCBI chr17:34,245,007...34,247,029
Ensembl chr17:34,245,007...34,247,034
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G |
Hsd3b3 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of HSD3B3 mRNA] |
CTD |
PMID:26769589 |
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NCBI chr 3:98,648,792...98,672,465
Ensembl chr 3:98,648,839...98,670,443
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G |
Hsf1 |
heat shock factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased activity of HSF1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter affects the localization of HSF1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HSF1 promoter]]; Acetylcysteine inhibits the reaction [Vehicle Emissions affects the localization of HSF1 protein] |
CTD |
PMID:10403520 PMID:17922515 PMID:30309986 |
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NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
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G |
Hsp90aa1 |
heat shock protein 90, alpha (cytosolic), class A member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of HSP90AA1 mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of HSP90AA1 protein]] |
CTD |
PMID:37422542 |
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NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
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G |
Hsp90b1 |
heat shock protein 90, beta (Grp94), member 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSP90B1 mRNA]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of HSP90B1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSP90B1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSP90B1 protein] Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of HSP90B1 protein] Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HSP90B1 protein] |
CTD |
PMID:21145380 PMID:21533816 PMID:21911445 PMID:25451595 PMID:25950987 PMID:31330229 More...
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NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
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G |
Hspa1a |
heat shock protein 1A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HSPA1A mRNA]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HSPA1A protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of HSPA1A mRNA] Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSPA1A protein] |
CTD |
PMID:12231548 PMID:16324719 PMID:18723479 PMID:36813253 |
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NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
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G |
Hspa1b |
heat shock protein 1B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HSPA1B mRNA] Acetylcysteine inhibits the reaction [arsenite results in increased expression of HSPA1B protein] |
CTD |
PMID:15175009 PMID:18723479 |
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NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
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G |
Hspa5 |
heat shock protein 5 |
increases expression multiple interactions decreases expression |
ISO EXP |
Acetylcysteine results in increased expression of HSPA5 protein Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [dibromoacetonitrile results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [(4-methyl-1-naphthyl)-(1-pentylindol-3-yl)methanone results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [discretamine results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Ethylmercury Compounds affects the expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [hesperetin results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Ursolic Acid results in increased expression of HSPA5 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]] Acetylcysteine results in decreased expression of HSPA5 protein Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [[INS co-treated with Acrylamide] results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of HSPA5 protein] |
CTD |
PMID:19722195 PMID:20493918 PMID:21145380 PMID:21198628 PMID:21533816 PMID:21911445 PMID:24157283 PMID:24291486 PMID:24802810 PMID:25341683 PMID:25451595 PMID:25950987 PMID:26772155 PMID:27484784 PMID:27511942 PMID:27784618 PMID:27816613 PMID:28296042 PMID:28754437 PMID:30502353 PMID:30633982 PMID:31276663 PMID:31330229 PMID:32506763 PMID:32590070 PMID:34687772 PMID:37148176 PMID:37487865 PMID:38065397 PMID:38604440 More...
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NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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G |
Hspb1 |
heat shock protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenite results in increased expression of HSPB1 protein] |
CTD |
PMID:15175009 |
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NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
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G |
Hspd1 |
heat shock protein 1 (chaperonin) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of HSPD1 mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of HSPD1 protein]]; Acetylcysteine inhibits the reaction [Chlorine results in increased expression of HSPD1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of HSPD1 mRNA] |
CTD |
PMID:32092105 PMID:35065218 PMID:37422542 |
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NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
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G |
Htatip2 |
HIV-1 Tat interactive protein 2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of HTATIP2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 7:49,408,761...49,423,748
Ensembl chr 7:49,408,863...49,423,723
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G |
Icam1 |
intercellular adhesion molecule 1 |
affects expression multiple interactions decreases expression |
ISO EXP |
Acetylcysteine affects the expression of ICAM1 Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ICAM1 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased secretion of ICAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] Acetylcysteine results in decreased expression of ICAM1 mRNA Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of ICAM1 mRNA] Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Tin Fluorides results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 protein] |
CTD |
PMID:10495789 PMID:10792388 PMID:11736926 PMID:17416599 PMID:17666914 PMID:19642688 PMID:20885979 PMID:22093110 PMID:23114885 PMID:25876056 PMID:26683377 PMID:26901245 PMID:29329563 PMID:30842373 PMID:35349355 More...
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NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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G |
Id2 |
inhibitor of DNA binding 2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of ID2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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G |
Idh2 |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of IDH2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDH2 protein] |
CTD |
PMID:30104959 |
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NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
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G |
Ier3 |
immediate early response 3 |
multiple interactions affects response to substance |
EXP |
Acetylcysteine affects the reaction [IER3 protein affects the expression of GNAI2 mRNA] IER3 protein affects the susceptibility to Acetylcysteine |
CTD |
PMID:20713914 |
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NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
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G |
Ier5 |
immediate early response 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of IER5 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 1:154,972,113...154,975,382
Ensembl chr 1:154,972,107...154,975,382
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]] |
CTD |
PMID:34051100 |
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NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IFNG protein]; Acetylcysteine inhibits the reaction [Eosine I Bluish results in increased expression of IFNG mRNA]; Acetylcysteine inhibits the reaction [Formaldehyde results in decreased expression of IFNG mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IFNG protein] Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IFNG protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein] Acetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA] |
CTD |
PMID:12847270 PMID:15004186 PMID:18849615 PMID:20431929 PMID:22440610 PMID:24810974 PMID:26138014 PMID:32620109 More...
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NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of IFRD1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr12:40,253,128...40,273,184
Ensembl chr12:40,251,566...40,298,503
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of IRS1 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IGF1 protein] |
CTD |
PMID:17458902 PMID:26138014 |
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NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
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G |
Igf1r |
insulin-like growth factor I receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IGF1R protein] |
CTD |
PMID:21195169 |
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NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of IGFBP1 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IGFBP1 protein] |
CTD |
PMID:22129741 PMID:26138014 |
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NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
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G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of IGFBP2 protein] |
CTD |
PMID:26138014 |
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NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of IGFBP4 protein] |
CTD |
PMID:26138014 |
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NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218
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G |
Ikbkb |
inhibitor of kappaB kinase beta |
decreases activity multiple interactions |
ISO EXP |
Acetylcysteine results in decreased activity of IKBKB protein Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein] Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IKBKB mRNA] |
CTD |
PMID:17395010 PMID:34310962 PMID:37458150 |
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NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
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G |
Il10 |
interleukin 10 |
multiple interactions |
EXP ISO |
[Eugenol co-treated with Acetylcysteine] inhibits the reaction [Nicotine results in decreased secretion of IL10 protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 protein]; Acetylcysteine inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Nicotine results in decreased expression of IL10 mRNA] Acetylcysteine inhibits the reaction [Methotrexate results in decreased secretion of IL10 protein]; Acetylcysteine promotes the reaction [Doxorubicin results in increased expression of IL10 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL10 protein] |
CTD |
PMID:11124598 PMID:20431929 PMID:20885979 PMID:21237301 PMID:21424515 PMID:26138014 PMID:32620109 PMID:37598416 PMID:37860953 More...
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NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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G |
Il10rb |
interleukin 10 receptor, beta |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of IL10RB mRNA |
CTD |
PMID:16084531 |
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NCBI chr16:91,203,166...91,222,718
Ensembl chr16:91,203,052...91,222,722
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G |
Il12a |
interleukin 12a |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] |
CTD |
PMID:21237301 |
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NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
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G |
Il12b |
interleukin 12b |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] |
CTD |
PMID:21237301 |
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NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
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G |
Il13 |
interleukin 13 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL13 protein] |
CTD |
PMID:26138014 |
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NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
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G |
Il15 |
interleukin 15 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL15 protein] |
CTD |
PMID:26138014 |
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NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
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G |
Il16 |
interleukin 16 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL16 protein] |
CTD |
PMID:26138014 |
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NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934
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G |
Il17a |
interleukin 17A |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL17A protein]; Acetylcysteine inhibits the reaction [Trichloroethylene results in increased expression of IL17A mRNA] |
CTD |
PMID:20431929 PMID:23993974 |
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NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
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G |
Il17d |
interleukin 17D |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of IL17D mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:57,762,197...57,780,623
Ensembl chr14:57,762,234...57,780,623
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G |
Il18 |
interleukin 18 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL18 protein] Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL18 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL18 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [piperlongumine results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased secretion of IL18 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]] Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] |
CTD |
PMID:27311643 PMID:30205151 PMID:34510229 PMID:34791735 PMID:35020164 PMID:35285579 PMID:35777681 PMID:36055550 PMID:36646296 PMID:37300869 PMID:37393521 PMID:38242274 More...
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NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO EXP |
[Acetylcysteine co-treated with IL1A protein] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [butylphen results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]; Acetylcysteine promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]] Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in increased secretion of IL1A protein] |
CTD |
PMID:7476933 PMID:24570342 PMID:26138014 PMID:28836394 PMID:37778984 |
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NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
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G |
Il1b |
interleukin 1 beta |
multiple interactions affects expression decreases expression increases expression |
ISO EXP |
Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL1B protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Buthionine Sulfoximine co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B protein] Acetylcysteine affects the expression of IL1B protein Acetylcysteine results in decreased expression of IL1B mRNA [Acetylcysteine co-treated with raubasine] results in increased secretion of IL1B protein; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL1B mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL1B protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased secretion of IL1B protein] [Acetylcysteine co-treated with Cobalt] results in decreased expression of IL1B protein; Acetylcysteine affects the reaction [diallyl trisulfide results in increased expression of and results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein modified form]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [2,4-decadienal results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[IL1B protein co-treated with Oligomycins] results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[Oligomycins co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of IL1B mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Cobalt results in increased expression of IL1B protein modified form]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; Acetylcysteine inhibits the reaction [IL1B protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL1B mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [piperlongumine results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of IL1B protein modified form]; Acetylcysteine inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [xanthohumol results in increased expression of IL1B protein]; Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Acetylcysteine promotes the reaction [titanium dioxide results in increased secretion of IL1B protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]] Acetylcysteine results in increased expression of IL1B protein |
CTD |
PMID:10541287 PMID:11970852 PMID:16014734 PMID:16214328 PMID:18257742 PMID:18403674 PMID:19281832 PMID:21424515 PMID:21703343 PMID:21779360 PMID:22385246 PMID:22549761 PMID:22867088 PMID:23159886 PMID:23900960 PMID:23940760 PMID:23948867 PMID:24570342 PMID:24609059 PMID:24810974 PMID:25406100 PMID:26086368 PMID:26138014 PMID:26332274 PMID:26435000 PMID:26801986 PMID:26809137 PMID:26901245 PMID:27311643 PMID:27393034 PMID:27783111 PMID:28004443 PMID:28814068 PMID:30205151 PMID:30320338 PMID:30639957 PMID:30878009 PMID:30977640 PMID:31629901 PMID:32620109 PMID:32687961 PMID:32805375 PMID:34238121 PMID:34510229 PMID:34791735 PMID:34863858 PMID:35190838 PMID:35285579 PMID:35349355 PMID:35833596 PMID:36055550 PMID:36347317 PMID:36354081 PMID:36493885 PMID:36646296 PMID:36762617 PMID:36880428 PMID:37300869 PMID:37369159 PMID:37393521 PMID:37422542 PMID:37458150 PMID:37598416 PMID:37692514 PMID:38064316 PMID:38242274 PMID:38821455 PMID:39260547 More...
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NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of IL2 mRNA; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of IL2 protein] Acetylcysteine inhibits the reaction [Fenitrothion results in increased secretion of IL2 protein] |
CTD |
PMID:22429591 PMID:22910795 PMID:31173782 |
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NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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G |
Il22b |
interleukin 22B |
multiple interactions |
EXP |
IL22 protein promotes the reaction [Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GPT protein]] |
CTD |
PMID:23375450 |
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NCBI chr10:118,125,534...118,130,943
Ensembl chr10:118,125,534...118,130,943
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G |
Il24 |
interleukin 24 |
decreases activity |
ISO |
Acetylcysteine results in decreased activity of IL24 protein |
CTD |
PMID:14678967 |
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NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
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G |
Il27ra |
interleukin 27 receptor, alpha |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of IL27RA mRNA |
CTD |
PMID:16084531 |
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NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218
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G |
Il2ra |
interleukin 2 receptor, alpha chain |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]] |
CTD |
PMID:23134680 |
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NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
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G |
Il3 |
interleukin 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL3 protein] |
CTD |
PMID:26138014 |
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NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
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G |
Il33 |
interleukin 33 |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Soot results in increased expression of IL33 mRNA] |
CTD |
PMID:35776887 |
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NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL4 protein] |
CTD |
PMID:26138014 PMID:27634759 |
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NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
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G |
Il4ra |
interleukin 4 receptor, alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL4R mRNA] |
CTD |
PMID:29753051 |
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NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
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G |
Il5 |
interleukin 5 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL5 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL5 protein] |
CTD |
PMID:20431929 PMID:26138014 |
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NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL6 protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [[Buthionine Sulfoximine co-treated with Lipopolysaccharides] results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of IL6 protein] [Acetylcysteine co-treated with raubasine] results in increased secretion of IL6 protein; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL6 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL6 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]] [Acetylcysteine co-treated with Ascorbic Acid] inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of IL6 mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [calcium silicate results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL6 mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of IL6 protein] Acetylcysteine results in decreased expression of IL6 mRNA |
CTD |
PMID:9378980 PMID:10022265 PMID:11970852 PMID:16757516 PMID:17922515 PMID:18257742 PMID:20801209 PMID:21131394 PMID:21424515 PMID:21533553 PMID:21762757 PMID:21779360 PMID:21912612 PMID:22472292 PMID:23624824 PMID:24570342 PMID:24810974 PMID:26160521 PMID:27427241 PMID:27917510 PMID:28555929 PMID:28739487 PMID:29329563 PMID:29753051 PMID:30259999 PMID:32687961 PMID:32810504 PMID:32947957 PMID:33146789 PMID:35065218 PMID:35122928 PMID:35285579 PMID:35349355 PMID:35833596 PMID:36055550 PMID:36493885 PMID:36762617 PMID:36880428 PMID:37422542 PMID:37458150 PMID:37598416 PMID:37860953 PMID:38064316 PMID:38513841 PMID:39260547 More...
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NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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G |
Il7r |
interleukin 7 receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of IL7R mRNA alternative form]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN2A mRNA]] |
CTD |
PMID:35303175 |
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NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262
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G |
Ins1 |
insulin I |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of CEBPA protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of FABP4 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of PPARG protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in decreased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Acetylcysteine inhibits the reaction [tributyltin results in increased secretion of INS1 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [Fructose results in increased expression of INS1 protein]; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]] |
CTD |
PMID:15680273 PMID:16918248 PMID:20006636 PMID:21145380 PMID:23405080 PMID:27117918 PMID:28180948 More...
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NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
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G |
Ins2 |
insulin II |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Glucose results in increased expression of INS protein]; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]] Acetylcysteine inhibits the reaction [[INS co-treated with Acrylamide] results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [Dexamethasone inhibits the reaction [Glucose results in increased secretion of INS protein]] |
CTD |
PMID:16505238 PMID:21888768 PMID:28180948 PMID:38604440 |
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NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
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G |
Insig1 |
insulin induced gene 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of INSIG1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
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G |
Insr |
insulin receptor |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of INSR protein] Acetylcysteine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of INSR protein] |
CTD |
PMID:18569013 PMID:22917016 |
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NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
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G |
Ireb2 |
iron responsive element binding protein 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein] |
CTD |
PMID:18073202 |
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NCBI chr 9:54,769,942...54,819,812
Ensembl chr 9:54,771,073...54,819,814
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of IRF1 protein] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of IRF1 mRNA |
CTD |
PMID:20525893 PMID:22129741 |
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NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
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G |
Irs1 |
insulin receptor substrate 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of IRS1 protein] |
CTD |
PMID:17458902 |
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NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of IRS2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
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G |
Itga2 |
integrin alpha 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of ITGA2 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of ITGA2 mRNA]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ITGA2 mRNA] |
CTD |
PMID:21635667 |
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NCBI chr13:114,969,617...115,068,588
Ensembl chr13:114,969,617...115,068,636
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G |
Itga2b |
integrin alpha 2b |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of ITGA2B protein] |
CTD |
PMID:20523355 |
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NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
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G |
Itgam |
integrin alpha M |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of ITGAM mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of ITGAM mRNA]] |
CTD |
PMID:29945211 |
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NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
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G |
Itgav |
integrin alpha V |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of ITGAV mRNA |
CTD |
PMID:16084531 |
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NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
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G |
Itgb1 |
integrin beta 1 (fibronectin receptor beta) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [DDT results in increased expression of ITGB1 mRNA] |
CTD |
PMID:24820114 |
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NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
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G |
Itgb3 |
integrin beta 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of ITGB3 protein] |
CTD |
PMID:20523355 |
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NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
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G |
Jag1 |
jagged 1 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of JAG1 mRNA Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of JAG1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of JAG1 mRNA] |
CTD |
PMID:16084531 PMID:20974985 |
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NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564
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G |
Jak1 |
Janus kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of JAK1 protein] |
CTD |
PMID:24820114 |
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NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
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G |
Jak2 |
Janus kinase 2 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein] Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JAK2 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of JAK2 protein in the stomach) N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid decreases phosphorylation of JAK2 protein in stomach] N-acetyl-L-cysteine inhibits the reaction [hispidulin decreases phoshphorylation of JAK2 protein in colon and colorectum] |
CTD RGD |
PMID:12847270 PMID:29894800 PMID:34627931 PMID:29408335 PMID:32106377 PMID:29575334 More...
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RGD:127284846, RGD:127284886, RGD:149735333 |
NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
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G |
Jun |
jun proto-oncogene |
decreases activity multiple interactions |
ISO EXP |
Acetylcysteine results in decreased activity of JUN protein Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Carbon Tetrachloride results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of and results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of JUN mRNA]; Acetylcysteine promotes the reaction [bis(maltolato)oxovanadium(IV) results in decreased activity of [FOS protein binds to JUN protein]] Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [[tungsten carbide co-treated with Cobalt] results in increased localization of and results in increased activity of JUN protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Chromium results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [FOS protein co-treated with JUN protein]]; Acetylcysteine inhibits the reaction [zinc chloride results in increased expression of JUN mRNA] Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of and results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with Disulfiram] results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [afimoxifene results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of JUN]; Acetylcysteine inhibits the reaction [darinaparsin results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Niclosamide results in increased phosphorylation of JUN protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Morphine results in increased phosphorylation of and results in increased activity of JUN protein]; Acetylcysteine inhibits the reaction [Niclosamide results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of JUN protein] |
CTD |
PMID:7743507 PMID:8797811 PMID:8825185 PMID:8853906 PMID:9043100 PMID:9890986 PMID:10397638 PMID:10692565 PMID:11306679 PMID:15252869 PMID:15520183 PMID:15945272 PMID:17458902 PMID:17696279 PMID:18569013 PMID:18633430 PMID:19038359 PMID:19292871 PMID:19654923 PMID:19747498 PMID:19935718 PMID:20632440 PMID:20654705 PMID:21635667 PMID:22260869 PMID:22288910 PMID:23033007 PMID:24750999 PMID:30796935 PMID:31229567 PMID:32540572 PMID:35689653 PMID:36813253 More...
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NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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G |
Junb |
jun B proto-oncogene |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA] |
CTD |
PMID:15520183 |
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NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
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G |
Kcnh5 |
potassium voltage-gated channel, subfamily H (eag-related), member 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCNH5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr12:74,943,991...75,224,625
Ensembl chr12:74,943,994...75,224,106
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G |
Kcnq5 |
potassium voltage-gated channel, subfamily Q, member 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCNQ5 mRNA Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of KCNQ5 mRNA] |
CTD |
PMID:22129741 PMID:31004932 |
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NCBI chr 1:21,468,623...22,032,874
Ensembl chr 1:21,468,627...22,032,166
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G |
Kctd4 |
potassium channel tetramerisation domain containing 4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCTD4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:76,192,443...76,202,657
Ensembl chr14:76,192,449...76,203,646
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G |
Kdm2a |
lysine (K)-specific demethylase 2A |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of KDM2A protein] Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [KDM2A protein binds to CDKN2A promoter]] |
CTD |
PMID:31551408 |
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NCBI chr19:4,366,172...4,448,749
Ensembl chr19:4,364,447...4,448,313
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G |
Kdr |
kinase insert domain protein receptor |
increases expression |
ISO |
Acetylcysteine results in increased expression of KDR protein |
CTD |
PMID:17992120 |
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NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
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G |
Keap1 |
kelch-like ECH-associated protein 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein]; Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] Acetylcysteine inhibits the reaction [Copper Sulfate results in decreased expression of KEAP1 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in decreased expression of KEAP1 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of KEAP1 protein] |
CTD |
PMID:11909699 PMID:19033392 PMID:30104959 PMID:37353053 PMID:37369159 |
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NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
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G |
Kif2c |
kinesin family member 2C |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of KIF2C protein] |
CTD |
PMID:28343997 |
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NCBI chr 4:117,016,830...117,039,821
Ensembl chr 4:117,016,836...117,039,836
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G |
Kitl |
kit ligand |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of KITLG protein] |
CTD |
PMID:26138014 |
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NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
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G |
Kl |
klotho |
multiple interactions increases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [Cyclosporine results in decreased expression of KL protein] Acetylcysteine inhibits the reaction [Indican results in decreased expression of KL mRNA]; Acetylcysteine inhibits the reaction [Indican results in decreased expression of KL protein] Acetylcysteine results in increased expression of KL protein |
CTD |
PMID:21389697 PMID:23183129 PMID:23765110 |
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NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282
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G |
Klf4 |
Kruppel-like transcription factor 4 (gut) |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of KLF4 mRNA] |
CTD |
PMID:36315628 |
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NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
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G |
Kmt2a |
lysine (K)-specific methyltransferase 2A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of KMT2A protein] |
CTD |
PMID:31551408 |
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NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594
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G |
Kras |
Kirsten rat sarcoma viral oncogene homolog |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [manumycin results in decreased activity of KRAS protein] |
CTD |
PMID:19409983 |
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NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
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G |
Kremen2 |
kringle containing transmembrane protein 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KREMEN2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr17:23,960,173...23,965,305
Ensembl chr17:23,960,171...23,964,807
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G |
Krt10 |
keratin 10 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of KRT10 protein] |
CTD |
PMID:31551408 |
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NCBI chr11:99,276,080...99,288,631
Ensembl chr11:99,276,080...99,280,190
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G |
Krt6a |
keratin 6A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [titanium dioxide results in decreased expression of KRT6A mRNA] |
CTD |
PMID:20932892 |
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NCBI chr15:101,598,363...101,602,746
Ensembl chr15:101,598,345...101,602,742
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G |
Krt8 |
keratin 8 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein] |
CTD |
PMID:15939799 |
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NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917
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G |
Lamp1 |
lysosomal-associated membrane protein 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]] Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of LAMP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LAMP1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA] Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein] |
CTD |
PMID:28347754 PMID:29307831 PMID:31319114 PMID:33462182 PMID:35550146 |
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NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338
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G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased secretion of LDHA protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of LDHA mRNA]; Acetylcysteine inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of LDHA mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LDHA mRNA]; Acetylcysteine inhibits the reaction [3-monochloropropane-1, 2 diol ester results in increased secretion of LDHA protein]; Acetylcysteine inhibits the reaction [DDT results in increased expression of LDHA mRNA]; Acetylcysteine inhibits the reaction [icaritin results in decreased expression of LDHA protein] |
CTD |
PMID:21671307 PMID:30821169 PMID:31251971 PMID:31724279 PMID:36000575 PMID:38408632 PMID:38431053 More...
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NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
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G |
Ldhb |
lactate dehydrogenase B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] |
CTD |
PMID:21671307 |
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NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
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G |
Lgalsl |
galectin like |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LGALSL mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:20,773,355...20,781,916
Ensembl chr11:20,773,576...20,781,056
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G |
Lhb |
luteinizing hormone beta |
multiple interactions increases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of PGR mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] Acetylcysteine results in increased expression of LHB protein Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of LHB protein] |
CTD |
PMID:21220312 PMID:30633982 |
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NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
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G |
Lhx8 |
LIM homeobox protein 8 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LHX8 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:154,011,925...154,036,190
Ensembl chr 3:154,011,931...154,036,296
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G |
Lipe |
lipase, hormone sensitive |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of LIPE protein] |
CTD |
PMID:30648648 |
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NCBI chr 7:25,078,952...25,097,911
Ensembl chr 7:25,078,952...25,098,135
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G |
Lmnb1 |
lamin B1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone results in increased expression of and affects the localization of LMNB1 protein] |
CTD |
PMID:38604309 |
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NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496
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G |
Lonp1 |
lon peptidase 1, mitochondrial |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of LONP1 mRNA] |
CTD |
PMID:36315628 |
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NCBI chr17:56,921,297...56,933,903
Ensembl chr17:56,921,297...56,933,887
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G |
Lpin1 |
lipin 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LPIN1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967
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G |
Lrrk2 |
leucine-rich repeat kinase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of LRRK2 protein] Acetylcysteine inhibits the reaction [Cadmium results in increased expression of LRRK2 mRNA]; Acetylcysteine inhibits the reaction [Lead results in increased expression of LRRK2 mRNA] |
CTD |
PMID:34816377 PMID:34897981 |
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NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323
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G |
Ly9 |
lymphocyte antigen 9 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LY9 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:171,416,172...171,434,917
Ensembl chr 1:171,416,192...171,434,978
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G |
Lyplal1 |
lysophospholipase-like 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LYPLAL1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:185,819,929...185,849,507
Ensembl chr 1:185,819,928...185,849,507
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G |
Lyzl4 |
lysozyme-like 4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LYZL4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:121,406,907...121,471,187
Ensembl chr 9:121,406,909...121,471,162
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G |
Madcam1 |
mucosal vascular addressin cell adhesion molecule 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein] |
CTD |
PMID:12388057 |
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NCBI chr10:79,500,393...79,504,376
Ensembl chr10:79,500,393...79,504,371
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G |
Malat1 |
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of MALAT1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr19:5,845,718...5,852,700
Ensembl chr19:5,845,717...5,853,602
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G |
Maoa |
monoamine oxidase A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in decreased expression of MAOA protein] |
CTD |
PMID:38642822 |
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NCBI chr X:16,485,937...16,554,051
Ensembl chr X:16,485,937...16,554,057
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased lipidation of and results in increased localization of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased metabolism of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Apigenin results in increased expression of MAP1LC3B protein modified form]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B mRNA]; Acetylcysteine inhibits the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [aumolertinib results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [butein results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [cryptotanshinone results in increased expression of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Deuterium Oxide results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [dimethyl alpha-ketoglutarate results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [ovatodiolide results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Vorinostat results in increased cleavage of MAP1LC3B protein]; Acetylcysteine promotes the reaction [Cadmium Chloride results in increased expression of MAP1LC3B protein]; Cadmium Chloride promotes the reaction [Acetylcysteine results in increased expression of MAP1LC3B protein modified form]; Cadmium Chloride promotes the reaction [Acetylcysteine results in increased expression of MAP1LC3B protein] Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [nonylphenol results in increased expression of MAP1LC3B protein] Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of MAP1LC3B mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion affects the expression of and results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]; Acetylcysteine inhibits the reaction [dibromoacetonitrile results in increased expression of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Indican results in increased expression of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate affects the localization of MAP1LC3B protein] Acetylcysteine results in increased expression of MAP1LC3B protein; Acetylcysteine results in increased expression of MAP1LC3B protein modified form |
CTD |
PMID:20543569 PMID:25301941 PMID:27832966 PMID:28347754 PMID:28600121 PMID:29247770 PMID:29307831 PMID:30849338 PMID:31319114 PMID:31368586 PMID:32512069 PMID:32687844 PMID:33002460 PMID:34219533 PMID:34238121 PMID:34547296 PMID:34580807 PMID:34861471 PMID:35130734 PMID:36111830 PMID:36739042 PMID:37148176 PMID:37678662 PMID:37751786 PMID:38000454 PMID:38065397 PMID:38521250 More...
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NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
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G |
Map2 |
microtubule-associated protein 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of MAP2 mRNA] Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein] |
CTD |
PMID:28153600 PMID:28499986 |
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NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
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G |
Map2k1 |
mitogen-activated protein kinase kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K1 protein] |
CTD |
PMID:18703135 |
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NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
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G |
Map2k2 |
mitogen-activated protein kinase kinase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein] |
CTD |
PMID:18703135 |
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NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
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G |
Map2k3 |
mitogen-activated protein kinase kinase 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K3 protein] |
CTD |
PMID:18703135 |
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NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637
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G |
Map2k4 |
mitogen-activated protein kinase kinase 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K4 protein] Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K4 protein] N-acetyl-L-cysteine inhibits the reaction [Curcumin increases phosphorylation of MAP2K4 protein in uterine cervix] |
CTD RGD |
PMID:18703135 PMID:22085843 PMID:25198898 |
RGD:150429751 |
NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K6 protein] |
CTD |
PMID:18703135 |
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NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Rotenone inhibits the reaction [TXN protein binds to and results in decreased activity of MAP3K5 protein]] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP3K5 protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAP3K5 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP3K5 protein]; Acetylcysteine inhibits the reaction [indole-3-carbinol results in decreased expression of and results in increased phosphorylation of MAP3K5 protein]; Acetylcysteine inhibits the reaction [platycodin D affects the phosphorylation of and results in increased activity of MAP3K5 protein]; Acetylcysteine inhibits the reaction [Quercetin results in decreased phosphorylation of and results in increased activity of MAP3K5 protein] N-acetyl-L-cysteine co-treated with Curcumin increases phosphorylation of MAP3K5 protein in uterine cervix |
CTD RGD |
PMID:16449798 PMID:18703135 PMID:20083342 PMID:22784044 PMID:33039870 PMID:33118390 PMID:25198898 More...
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RGD:150429751 |
NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
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G |
Mapk1 |
mitogen-activated protein kinase 1 |
increases phosphorylation decreases phosphorylation multiple interactions |
ISO EXP |
Acetylcysteine results in increased phosphorylation of MAPK1 protein Acetylcysteine results in decreased phosphorylation of MAPK1 protein [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK1 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine affects the reaction [Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[tungsten carbide co-treated with Cobalt] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]] Acetylcysteine affects the reaction [Cadmium results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[cobaltous chloride results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Acetaldehyde results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of and results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [raiser results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Acetylcysteine results in increased phosphorylation of MAPK1 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased activity of and results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [acacetin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of and results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [ceric oxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Daunorubicin results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [dihydromyricetin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [morusin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Quinacrine results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [shikonin results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Thimerosal results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Thiostrepton results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased phosphorylation of MAPK1 protein]; Acetylcysteine results in increased activity of and results in increased phosphorylation of MAPK1 protein; Acetylcysteine results in increased phosphorylation of and results in increased activity of MAPK1 protein |
CTD |
PMID:8616849 PMID:10658192 PMID:12065697 PMID:12690112 PMID:12717738 PMID:14516795 PMID:14623829 PMID:15228596 PMID:15252869 PMID:15978937 PMID:16014620 PMID:16024921 PMID:16251475 PMID:16261333 PMID:16445087 PMID:16603213 PMID:16632126 PMID:16983658 PMID:17458902 PMID:17596522 PMID:17645304 PMID:17828457 PMID:18357586 PMID:18375950 PMID:18495191 PMID:18629305 PMID:18703135 PMID:19038359 PMID:19747498 PMID:20951154 PMID:21055460 PMID:21135414 PMID:21145380 PMID:21220312 PMID:21391979 PMID:21533816 PMID:21549813 PMID:21843585 PMID:21998720 PMID:22085843 PMID:22134701 PMID:22288910 PMID:22700867 PMID:22761781 PMID:22767315 PMID:22867088 PMID:22910795 PMID:23370007 PMID:23405080 PMID:23416263 PMID:23577223 PMID:23774252 PMID:23836369 PMID:23876460 PMID:24019090 PMID:24401988 PMID:24463199 PMID:24582688 PMID:25199686 PMID:25246272 PMID:25531190 PMID:25724548 PMID:25876056 PMID:26514923 PMID:27539140 PMID:28555929 PMID:28600122 PMID:28867437 PMID:29087013 PMID:29155359 PMID:29248572 PMID:29248592 PMID:29486182 PMID:30055241 PMID:30766661 PMID:30849338 PMID:30871965 PMID:30917517 PMID:31068539 PMID:31313457 PMID:31724279 PMID:31790703 PMID:31837377 PMID:31860779 PMID:31900833 PMID:32305283 PMID:32683294 PMID:32745510 PMID:33030807 PMID:33035517 PMID:33421718 PMID:34439521 PMID:34510229 PMID:34520753 PMID:34580807 PMID:34890707 PMID:34963561 PMID:35122928 PMID:35833596 PMID:36740148 PMID:36813253 PMID:38670245 PMID:39197814 More...
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NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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G |
Mapk10 |
mitogen-activated protein kinase 10 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK10 protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK10 protein] |
CTD |
PMID:15173093 |
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NCBI chr 5:103,056,413...103,359,200
Ensembl chr 5:103,055,814...103,359,200
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G |
Mapk11 |
mitogen-activated protein kinase 11 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in increased phosphorylation of MAPK11 protein] |
CTD |
PMID:38642822 |
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NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831
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G |
Mapk12 |
mitogen-activated protein kinase 12 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in increased phosphorylation of MAPK12 protein] |
CTD |
PMID:38642822 |
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NCBI chr15:89,014,787...89,025,270
Ensembl chr15:89,014,787...89,024,906
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G |
Mapk13 |
mitogen-activated protein kinase 13 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK13 protein] Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in increased phosphorylation of MAPK13 protein] |
CTD |
PMID:28087840 PMID:38642822 |
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NCBI chr17:28,988,260...28,997,678
Ensembl chr17:28,988,271...28,999,207
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G |
Mapk14 |
mitogen-activated protein kinase 14 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [Emodin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]; Acetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [icaritin results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK14 protein] Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein] [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK14 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:12684028 PMID:14729614 PMID:15650392 PMID:17237268 PMID:18703135 PMID:19767766 PMID:21635667 PMID:28087840 PMID:35833596 PMID:38431053 PMID:38642822 PMID:39260547 More...
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NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
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G |
Mapk3 |
mitogen-activated protein kinase 3 |
increases phosphorylation decreases phosphorylation multiple interactions |
ISO EXP |
Acetylcysteine results in increased phosphorylation of MAPK3 protein Acetylcysteine results in decreased phosphorylation of MAPK3 protein [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK3 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine affects the reaction [Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[tungsten carbide co-treated with Cobalt] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK3 protein modified form]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]] Acetylcysteine affects the reaction [Cadmium results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[cobaltous chloride results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Acetaldehyde results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK3 protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of and results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [raiser results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Acetylcysteine results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased activity of and results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [acacetin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of and results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [ceric oxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Daunorubicin results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [dihydromyricetin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK3 protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [morusin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Quinacrine results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [shikonin results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Thimerosal results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Thiostrepton results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased phosphorylation of MAPK3 protein]; Acetylcysteine results in increased activity of and results in increased phosphorylation of MAPK3 protein; Acetylcysteine results in increased phosphorylation of and results in increased activity of MAPK3 protein |
CTD |
PMID:8616849 PMID:12065697 PMID:12690112 PMID:12717738 PMID:14516795 PMID:14623829 PMID:15228596 PMID:15252869 PMID:15978937 PMID:16014620 PMID:16024921 PMID:16251475 PMID:16261333 PMID:16445087 PMID:16603213 PMID:16632126 PMID:16983658 PMID:17458902 PMID:17596522 PMID:17645304 PMID:17828457 PMID:18357586 PMID:18375950 PMID:18495191 PMID:18629305 PMID:18703135 PMID:19038359 PMID:19747498 PMID:20951154 PMID:21055460 PMID:21135414 PMID:21145380 PMID:21220312 PMID:21391979 PMID:21533816 PMID:21549813 PMID:21843585 PMID:21998720 PMID:22085843 PMID:22134701 PMID:22288910 PMID:22700867 PMID:22761781 PMID:22767315 PMID:22867088 PMID:22910795 PMID:23405080 PMID:23416263 PMID:23577223 PMID:23774252 PMID:23836369 PMID:23876460 PMID:24019090 PMID:24401988 PMID:24463199 PMID:24582688 PMID:25199686 PMID:25246272 PMID:25531190 PMID:25724548 PMID:25876056 PMID:26514923 PMID:27539140 PMID:28555929 PMID:28600122 PMID:28867437 PMID:29087013 PMID:29155359 PMID:29248572 PMID:29248592 PMID:29486182 PMID:30055241 PMID:30766661 PMID:30849338 PMID:30871965 PMID:30917517 PMID:31068539 PMID:31313457 PMID:31724279 PMID:31790703 PMID:31837377 PMID:31860779 PMID:31900833 PMID:32305283 PMID:32683294 PMID:32745510 PMID:33030807 PMID:33035517 PMID:33421718 PMID:34439521 PMID:34510229 PMID:34520753 PMID:34580807 PMID:34890707 PMID:34963561 PMID:35122928 PMID:35833596 PMID:36740148 PMID:36813253 PMID:39197814 More...
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NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions decreases phosphorylation |
ISO EXP |
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of MAPK8 mRNA] [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK8 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]]; Acetylcysteine inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein] Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [butein results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [eriocitrin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [isoliensinine results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Spermine results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein] Acetylcysteine results in decreased phosphorylation of MAPK8 protein N-acetyl-L-cysteine inhibits the reaction [Curcumin increases phosphorylation of MAPK8 protein in uterine cervix] |
CTD RGD |
PMID:10397638 PMID:11306679 PMID:12684028 PMID:12902192 PMID:14687664 PMID:15173093 PMID:17041759 PMID:17481858 PMID:18412143 PMID:18728404 PMID:19654923 PMID:19760616 PMID:20121705 PMID:20632440 PMID:21135414 PMID:21145380 PMID:21391979 PMID:21958719 PMID:22085843 PMID:22767315 PMID:23836369 PMID:24386346 PMID:24735948 PMID:25531190 PMID:26219228 PMID:26514923 PMID:28087840 PMID:28600122 PMID:28801140 PMID:29248572 PMID:29458170 PMID:30259999 PMID:30550853 PMID:30633982 PMID:30766661 PMID:30796935 PMID:31229567 PMID:31313457 PMID:31790703 PMID:33039870 PMID:34510229 PMID:34520753 PMID:34724282 PMID:34861471 PMID:35122928 PMID:35130734 PMID:35512476 PMID:35689653 PMID:35833596 PMID:36070022 PMID:36813253 PMID:37598316 PMID:25198898 More...
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RGD:150429751 |
NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions decreases phosphorylation |
EXP ISO |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK9 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK9 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK9 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK9 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased phosphorylation of MAPK9 protein] Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK9 protein] Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK9 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK9 protein] Acetylcysteine results in decreased phosphorylation of MAPK9 protein |
CTD |
PMID:14687664 PMID:18412143 PMID:19654923 PMID:19760616 PMID:21135414 PMID:21145380 PMID:21391979 PMID:22085843 PMID:22767315 PMID:23836369 PMID:24386346 PMID:24735948 PMID:25531190 PMID:26514923 PMID:28801140 PMID:29248572 PMID:29458170 PMID:30766661 PMID:31229567 PMID:35122928 PMID:35689653 PMID:35833596 More...
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NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
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G |
Mapkapk2 |
MAP kinase-activated protein kinase 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of MAPKAPK2 protein] |
CTD |
PMID:21911445 |
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NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
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G |
Mapkapk3 |
mitogen-activated protein kinase-activated protein kinase 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of MAPKAPK3 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 9:107,132,125...107,167,082
Ensembl chr 9:107,132,126...107,167,076
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G |
Mapt |
microtubule-associated protein tau |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] Acetylcysteine inhibits the reaction [1,2-diacetylbenzene results in increased phosphorylation of MAPT protein] |
CTD |
PMID:24142891 PMID:28734998 |
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NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
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G |
Mcl1 |
myeloid cell leukemia sequence 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in decreased expression of MCL1 protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Vorinostat] results in decreased expression of MCL1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of MCL1 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased expression of MCL1 protein] Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of MCL1 mRNA] |
CTD |
PMID:15173093 PMID:21533816 PMID:23082001 PMID:31837377 PMID:31900833 |
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NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
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G |
Mcm8 |
minichromosome maintenance 8 homologous recombination repair factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [4-biphenylamine results in decreased expression of MCM8 protein] |
CTD |
PMID:32433928 |
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NCBI chr 2:132,658,061...132,686,117
Ensembl chr 2:132,658,061...132,686,117
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G |
Me1 |
malic enzyme 1, NADP(+)-dependent, cytosolic |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ME1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006
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G |
Mettl14 |
methyltransferase 14, N6-adenosine-methyltransferase subunit |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of METTL14 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of METTL14 protein] Acetylcysteine inhibits the reaction [Paraquat results in increased expression of METTL14 mRNA] |
CTD |
PMID:31004932 PMID:34425375 |
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NCBI chr 3:123,161,944...123,179,639
Ensembl chr 3:123,161,946...123,179,757
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G |
Mettl3 |
methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of METTL3 mRNA] Acetylcysteine inhibits the reaction [Paraquat results in increased expression of METTL3 mRNA] |
CTD |
PMID:31004932 PMID:34425375 |
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NCBI chr14:52,532,298...52,548,555
Ensembl chr14:52,532,298...52,542,585
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MFN1 protein] Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of MFN1 protein] Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of MFN1 protein] |
CTD |
PMID:31408635 PMID:37084995 PMID:37499777 |
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NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [ALB protein modified form results in decreased expression of MFN2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of MFN2 protein] Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MFN2 protein] Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of MFN2 protein] |
CTD |
PMID:27997345 PMID:31408635 PMID:37084995 PMID:37499777 |
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NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
multiple interactions decreases activity increases expression |
ISO |
Acetylcysteine results in increased expression of and results in increased activity of MGMT protein Acetylcysteine results in decreased activity of MGMT protein Acetylcysteine results in increased expression of MGMT mRNA |
CTD |
PMID:16950796 |
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NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
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G |
Mir1247 |
microRNA 1247 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of MIR1247 mRNA] |
CTD |
PMID:25092309 |
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NCBI chr12:110,244,482...110,244,563
Ensembl chr12:110,244,482...110,244,563
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G |
Mir143 |
microRNA 143 |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of MIR143 mRNA Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of MIR143 mRNA] |
CTD |
PMID:37597758 |
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NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329
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G |
Mir144 |
microRNA 144 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of MIR144 mRNA] |
CTD |
PMID:23584289 |
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NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896
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G |
Mir182 |
microRNA 182 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MIR182 mRNA] |
CTD |
PMID:29662624 |
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NCBI chr 6:30,165,917...30,165,991
Ensembl chr 6:30,165,917...30,165,991
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G |
Mir21a |
microRNA 21a |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of MIR21 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions affects the expression of MIR21 mRNA] Acetylcysteine inhibits the reaction [[Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of MIR21 mRNA] |
CTD |
PMID:23584289 PMID:27323401 PMID:31928237 |
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NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
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G |
Mir23b |
microRNA 23b |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of MIR23B mRNA] |
CTD |
PMID:25092309 |
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NCBI chr13:63,448,298...63,448,371
Ensembl chr13:63,448,298...63,448,371
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G |
Mir26a-1 |
microRNA 26a-1 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with necrostatin-1] results in decreased expression of MIR26A |
CTD |
PMID:37422542 |
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NCBI chr 9:118,860,864...118,860,953
Ensembl chr 9:118,860,864...118,860,953
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G |
Mir28a |
microRNA 28a |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of MIR28 mRNA] |
CTD |
PMID:25092309 |
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NCBI chr16:24,646,605...24,646,690
Ensembl chr16:24,646,605...24,646,690
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G |
Mir29b-1 |
microRNA 29b-1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of MIR29B1 mRNA] |
CTD |
PMID:31928237 |
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NCBI chr 6:31,039,958...31,040,028
Ensembl chr 6:31,039,958...31,040,028
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G |
Mir761 |
microRNA 761 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of MIR761 mRNA] |
CTD |
PMID:23867156 |
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NCBI chr 4:108,874,852...108,874,927
Ensembl chr 4:108,874,852...108,874,927
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G |
Mitf |
melanogenesis associated transcription factor |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] |
CTD |
PMID:29486182 |
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NCBI chr 6:97,783,966...97,998,321
Ensembl chr 6:97,784,013...97,998,310
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G |
Mki67 |
antigen identified by monoclonal antibody Ki 67 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [1,12-benzoperylene results in increased expression of MKI67 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of MKI67 protein] |
CTD |
PMID:31518672 PMID:32745510 |
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NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
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G |
Mlc1 |
megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human) |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MLC1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:88,840,087...88,863,192
Ensembl chr15:88,840,087...88,863,210
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G |
Mlh1 |
mutL homolog 1 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of MLH1 mRNA; Acetylcysteine inhibits the reaction [sodium arsenite affects the expression of MLH1 protein] |
CTD |
PMID:28690196 PMID:29854080 |
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NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859
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G |
Mlkl |
mixed lineage kinase domain-like |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [3-monochloropropane-1, 2 diol ester results in increased expression of and results in increased phosphorylation of MLKL protein]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of MLKL mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of MLKL protein]]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of MLKL protein] [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MLKL mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MLKL protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MLKL mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MLKL protein]]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of MLKL protein] Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of MLKL protein] |
CTD |
PMID:30378427 PMID:35833596 PMID:36000575 PMID:37422542 PMID:37678662 PMID:38408632 More...
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NCBI chr 8:112,037,879...112,065,081
Ensembl chr 8:112,038,429...112,064,809
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G |
Mmp10 |
matrix metallopeptidase 10 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP10 protein] |
CTD |
PMID:17395008 |
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NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
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G |
Mmp12 |
matrix metallopeptidase 12 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Ethanol results in increased expression of MMP12 mRNA] |
CTD |
PMID:23978445 |
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NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP13 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP13 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP13 protein]] |
CTD |
PMID:17395008 PMID:34791735 |
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NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
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G |
Mmp1b |
matrix metallopeptidase 1b (interstitial collagenase) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Acetylcysteine inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA] |
CTD |
PMID:17449795 PMID:19136476 PMID:21635667 PMID:29731195 |
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NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions decreases activity |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of MMP2 mRNA] Acetylcysteine results in decreased activity of MMP2 protein Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of MMP2 protein]; Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [tomentosin results in decreased activity of MMP2 protein] |
CTD |
PMID:15451797 PMID:15962302 PMID:16213474 PMID:21540248 PMID:21635667 PMID:30917517 PMID:36493885 More...
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NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
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G |
Mmp25 |
matrix metallopeptidase 25 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP25 mRNA] |
CTD |
PMID:21635667 |
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NCBI chr17:23,847,289...23,864,006
Ensembl chr17:23,847,285...23,864,251
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP3 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP3 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP3 protein]] |
CTD |
PMID:17395008 PMID:34791735 |
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NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
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G |
Mmp7 |
matrix metallopeptidase 7 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [epigallocatechin gallate results in increased expression of MMP7 protein]; Acetylcysteine inhibits the reaction [Tretinoin results in increased expression of MMP7 mRNA] |
CTD |
PMID:17928719 |
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NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,587
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions decreases activity |
ISO EXP |
Acetylcysteine inhibits the reaction [4-aminophenylmercuriacetate results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Oxidopamine results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of MMP9 mRNA] Acetylcysteine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA] [Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of MMP9 mRNA; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Ethanol results in increased secretion of and results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [RELA protein binds to MMP9 promoter]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA] Acetylcysteine results in decreased activity of MMP9 protein |
CTD |
PMID:15451797 PMID:15557194 PMID:15962302 PMID:16213474 PMID:16251475 PMID:17015178 PMID:17603938 PMID:18930813 PMID:19350554 PMID:19371603 PMID:19962414 PMID:21051528 PMID:23774252 PMID:26514923 PMID:30766661 PMID:33437163 PMID:35065218 PMID:38971422 More...
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NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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G |
Moap1 |
modulator of apoptosis 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of MOAP1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920
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G |
Mov10l1 |
Mov10 like RISC complex RNA helicase 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MOV10L1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:88,867,094...88,939,355
Ensembl chr15:88,867,112...88,939,355
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Ethanol results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Gentamicins results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of MPO protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Smoke results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased activity of MPO protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased activity of MPO protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]] [MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine]; Acetylcysteine promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Acetylcysteine promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile] [Ethanol co-treated with Lipopolysaccharides co-treated with Acetylcysteine] results in increased activity of MPO protein; Acetylcysteine inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein] |
CTD |
PMID:11470263 PMID:17216608 PMID:17603938 PMID:20885979 PMID:22664789 PMID:23009681 PMID:24810974 PMID:25614581 PMID:25724285 PMID:32033504 PMID:37860953 More...
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NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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G |
Mrap |
melanocortin 2 receptor accessory protein |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MRAP mRNA |
CTD |
PMID:22129741 |
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NCBI chr16:90,535,095...90,546,673
Ensembl chr16:90,535,095...90,546,673
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G |
Mrc1 |
mannose receptor, C type 1 |
multiple interactions |
EXP |
[Paraquat co-treated with Acetylcysteine] results in decreased expression of MRC1 mRNA; [Paraquat co-treated with Acetylcysteine] results in decreased expression of MRC1 protein |
CTD |
PMID:34863858 |
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NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868
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G |
Ms4a8a |
membrane-spanning 4-domains, subfamily A, member 8A |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MS4A8A mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:11,044,835...11,058,467
Ensembl chr19:11,044,835...11,058,466
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G |
Msgn1 |
mesogenin 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MSGN1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr12:11,258,383...11,258,949
Ensembl chr12:11,258,361...11,258,973
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G |
Msh2 |
mutS homolog 2 |
multiple interactions |
ISO |
Acetylcysteine affects the reaction [Cadmium Chloride results in decreased expression of MSH2 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of MSH2 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite affects the expression of MSH2 protein] |
CTD |
PMID:28690196 PMID:33971260 |
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NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
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G |
Msh6 |
mutS homolog 6 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of MSH6 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of MSH6 protein] |
CTD |
PMID:28690196 |
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NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320
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G |
Msrb1 |
methionine sulfoxide reductase B1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MSRB1 mRNA] |
CTD |
PMID:36315628 |
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NCBI chr17:24,955,567...24,961,752
Ensembl chr17:24,955,616...24,961,752
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G |
Mstn |
myostatin |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of MSTN mRNA; Acetylcysteine results in decreased expression of MSTN protein |
CTD |
PMID:16968467 |
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NCBI chr 1:53,100,799...53,107,238
Ensembl chr 1:53,100,799...53,107,238
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G |
mt-Atp6 |
ATP synthase 6, mitochondrial |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP6 mRNA] |
CTD |
PMID:30104959 |
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NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607
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G |
mt-Atp8 |
ATP synthase 8, mitochondrial |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of ATP8 mRNA] |
CTD |
PMID:26980303 |
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NCBI chr MT:7,766...7,969
Ensembl chr MT:7,766...7,969
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G |
mt-Co1 |
cytochrome c oxidase I, mitochondrial |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of COX1 mRNA]; Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of COX1 mRNA] |
CTD |
PMID:26980303 PMID:30104959 |
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NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
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G |
mt-Cytb |
cytochrome b, mitochondrial |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CYTB mRNA] Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of CYTB mRNA] |
CTD |
PMID:30104959 PMID:30998386 |
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NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288
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G |
mt-Nd1 |
NADH dehydrogenase 1, mitochondrial |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of ND1 mRNA] |
CTD |
PMID:35403558 |
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NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707
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G |
mt-Nd2 |
NADH dehydrogenase 2, mitochondrial |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND2 mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of ND2 mRNA] Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of ND2 mRNA] |
CTD |
PMID:30104959 PMID:30998386 PMID:35403558 |
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NCBI chr MT:3,914...4,951
Ensembl chr MT:3,914...4,951
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G |
mt-Nd5 |
NADH dehydrogenase 5, mitochondrial |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND5 mRNA] Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of ND5 mRNA] |
CTD |
PMID:30104959 PMID:30998386 |
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NCBI chr MT:11,742...13,565
Ensembl chr MT:11,742...13,565
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G |
Mt1 |
metallothionein 1 |
multiple interactions |
EXP ISO |
[MT1 protein co-treated with MT2 protein] affects the reaction [Acetylcysteine affects the susceptibility to Doxorubicin] Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of MT1X mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of MT1X mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of MT1X mRNA]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of MT1X mRNA]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of MT1X mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of MT1A mRNA]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of MT1 mRNA]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT1A protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]] |
CTD |
PMID:9152014 PMID:18723479 PMID:20054154 PMID:20600803 PMID:25724285 PMID:27151894 PMID:29408318 More...
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NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
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G |
Mt2 |
metallothionein 2 |
multiple interactions decreases expression |
EXP ISO |
[MT1 protein co-treated with MT2 protein] affects the reaction [Acetylcysteine affects the susceptibility to Doxorubicin] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [gallium nitrate results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Nickel results in increased expression of MT2A mRNA] Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT2A protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]] Acetylcysteine results in decreased expression of MT2A mRNA |
CTD |
PMID:9545559 PMID:18586083 PMID:19097988 PMID:20600803 PMID:25724285 PMID:33188856 More...
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NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MTOR protein] Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of MTOR mRNA]; Acetylcysteine inhibits the reaction [Artesunate results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Biological Products results in decreased expression of MTOR protein modified form]; Acetylcysteine inhibits the reaction [butein results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Patulin results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased phosphorylation of MTOR protein] Acetylcysteine inhibits the reaction [Paraquat results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein] |
CTD |
PMID:21195169 PMID:23000059 PMID:26804764 PMID:27106530 PMID:28025121 PMID:28219700 PMID:28600122 PMID:29604266 PMID:30797898 PMID:31368586 PMID:31982503 PMID:33002460 PMID:35130734 PMID:35430258 PMID:36709824 PMID:36810933 PMID:37148176 PMID:37751786 PMID:38521250 More...
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NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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G |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MTR mRNA] |
CTD |
PMID:36315628 |
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NCBI chr13:12,196,217...12,273,090
Ensembl chr13:12,197,598...12,272,999
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G |
Muc5ac |
mucin 5, subtypes A and C, tracheobronchial/gastric |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MUC5AC mRNA]; Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MUC5AC protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC mRNA]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MUC5AC mRNA] |
CTD |
PMID:10640773 PMID:20709182 PMID:25177032 PMID:31622892 PMID:33421718 |
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NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
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G |
Muc5b |
mucin 5, subtype B, tracheobronchial |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [decabromobiphenyl ether results in increased expression of MUC5B mRNA]; Acetylcysteine inhibits the reaction [decabromobiphenyl ether results in increased expression of MUC5B protein] |
CTD |
PMID:31622892 |
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NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821
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G |
Muc6 |
mucin 6, gastric |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MUC6 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:141,212,404...141,241,659
Ensembl chr 7:141,213,373...141,241,641
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G |
Mx1 |
MX dynamin-like GTPase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]] |
CTD |
PMID:34051100 |
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NCBI chr16:97,248,235...97,264,106
Ensembl chr16:97,248,235...97,264,107
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G |
Myc |
myelocytomatosis oncogene |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of MYC protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with Cisplatin] results in decreased expression of MYC protein]; Acetylcysteine inhibits the reaction [Hydrocarbons, Chlorinated analog results in increased expression of MYC protein]; Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of MYC protein] Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of MYC mRNA]; Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of MYC mRNA]; Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of MYC mRNA] |
CTD |
PMID:15945272 PMID:16497787 PMID:21600978 PMID:22129741 PMID:24355586 PMID:29944906 PMID:33797725 More...
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NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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G |
Mycbpap |
MYCBP associated protein |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MYCBPAP mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of MYCBPAP mRNA] |
CTD |
PMID:22129741 |
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NCBI chr11:94,392,173...94,423,219
Ensembl chr11:94,392,173...94,412,568
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G |
Myd88 |
myeloid differentiation primary response gene 88 |
multiple interactions |
EXP ISO |
[Particulate Matter co-treated with Acetylcysteine co-treated with Polymyxin B] results in increased secretion of MYD88 protein; [Particulate Matter co-treated with Acetylcysteine] results in increased secretion of MYD88 protein; Acetylcysteine inhibits the reaction [benzanthrone results in increased expression of MYD88 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MYD88 mRNA]; MYD88 protein affects the reaction [[Acetylcysteine co-treated with Particulate Matter] results in increased secretion of CCL3 protein]; MYD88 protein affects the reaction [[Particulate Matter co-treated with Acetylcysteine co-treated with Polymyxin B] results in increased secretion of MYD88 protein]; MYD88 protein affects the reaction [[Particulate Matter co-treated with Acetylcysteine] results in increased secretion of MYD88 protein]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]] Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of MYD88 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of MYD88 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of MYD88 protein]] |
CTD |
PMID:28495615 PMID:28555929 PMID:36055550 PMID:37369159 |
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NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
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G |
Myh3 |
myosin, heavy polypeptide 3, skeletal muscle, embryonic |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Indican results in decreased expression of MYH3 protein] |
CTD |
PMID:29380555 |
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NCBI chr11:66,969,101...66,993,117
Ensembl chr11:66,969,126...66,993,112
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G |
Myog |
myogenin |
multiple interactions |
ISO EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MYOG mRNA Acetylcysteine inhibits the reaction [Indican results in decreased expression of MYOG protein] |
CTD |
PMID:22129741 PMID:29380555 |
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NCBI chr 1:134,217,742...134,220,286
Ensembl chr 1:134,217,727...134,220,286
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G |
Naglu |
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased activity of NAGLU protein] |
CTD |
PMID:37860953 |
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NCBI chr11:100,960,918...100,968,483
Ensembl chr11:100,960,838...100,968,498
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G |
Nanog |
Nanog homeobox |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [ovatodiolide results in decreased expression of NANOG protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NANOG protein] |
CTD |
PMID:32745510 PMID:39276908 |
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NCBI chr 6:122,684,448...122,691,592
Ensembl chr 6:122,684,448...122,691,592
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G |
Nbn |
nibrin |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of NBN protein]] |
CTD |
PMID:15489221 |
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NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589
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G |
Ncam2 |
neural cell adhesion molecule 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NCAM2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr16:80,997,501...81,425,549
Ensembl chr16:80,997,585...81,423,716
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of NCF1 protein Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NCF1 protein] Acetylcysteine inhibits the reaction [Aldrin results in increased expression of NCF1 mRNA]; Acetylcysteine inhibits the reaction [alpha-hexachlorocyclohexane results in increased expression of NCF1 mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of NCF1 mRNA]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of NCF1 mRNA] |
CTD |
PMID:21195169 PMID:28273962 PMID:29087013 |
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NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of NCF2 protein Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein] |
CTD |
PMID:21195169 |
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NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
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G |
Ncf4 |
neutrophil cytosolic factor 4 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NCF4 protein] Acetylcysteine results in decreased expression of NCF4 protein |
CTD |
PMID:21195169 |
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NCBI chr15:78,128,324...78,146,782
Ensembl chr15:78,129,001...78,146,780
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G |
Ncoa4 |
nuclear receptor coactivator 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of NCOA4 protein] |
CTD |
PMID:32687844 |
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NCBI chr14:31,881,884...31,901,210
Ensembl chr14:31,881,822...31,901,812
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G |
Ndufb6 |
NADH:ubiquinone oxidoreductase subunit B6 |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [Galactosamine results in decreased expression of NDUFB6 mRNA] Acetylcysteine results in increased expression of NDUFB6 protein |
CTD |
PMID:19523936 |
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NCBI chr 4:40,270,591...40,279,421
Ensembl chr 4:40,270,591...40,279,421
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G |
Ndufs7 |
NADH:ubiquinone oxidoreductase core subunit S7 |
increases expression |
ISO |
Acetylcysteine results in increased expression of NDUFS7 protein |
CTD |
PMID:19523936 |
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NCBI chr10:80,084,939...80,092,628
Ensembl chr10:80,084,955...80,092,628
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G |
Nedd9 |
neural precursor cell expressed, developmentally down-regulated gene 9 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of NEDD9 mRNA |
CTD |
PMID:16084531 |
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NCBI chr13:41,463,392...41,640,836
Ensembl chr13:41,463,057...41,640,838
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G |
Nefh |
neurofilament, heavy polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of NEFH protein] |
CTD |
PMID:26079211 |
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NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
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G |
Nefl |
neurofilament, light polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] |
CTD |
PMID:31969611 |
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NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
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G |
Nek4 |
NIMA (never in mitosis gene a)-related expressed kinase 4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NEK4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:30,673,334...30,710,778
Ensembl chr14:30,673,334...30,710,778
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G |
Nfatc1 |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 |
multiple interactions |
EXP |
Acetylcysteine affects the reaction [NFE2L2 protein affects the reaction [sodium arsenite affects the expression of NFATC1 protein]]; Acetylcysteine affects the reaction [sodium arsenite affects the expression of NFATC1 protein] |
CTD |
PMID:30742845 |
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NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286
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G |
Nfatc3 |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Arsenic affects the localization of NFATC3 protein] |
CTD |
PMID:31822296 |
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NCBI chr 8:106,785,450...106,857,169
Ensembl chr 8:106,785,472...106,857,169
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G |
Nfe2 |
nuclear factor, erythroid derived 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] |
CTD |
PMID:10656287 |
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NCBI chr15:103,156,640...103,166,809
Ensembl chr15:103,156,639...103,166,830
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G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
multiple interactions affects localization increases expression decreases expression |
EXP ISO |
[6-formylindolo(3,2-b)carbazole co-treated with Acetylcysteine] results in decreased expression of NFE2L2 mRNA; [Acetylcysteine co-treated with Particulate Matter] results in decreased expression of NFE2L2 mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine affects the reaction [NFE2L2 protein affects the reaction [sodium arsenite affects the expression of NFATC1 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein]]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter analog affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog affects the localization of NFE2L2 protein] [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased activity of NFE2L2 protein]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of NFE2L2 protein]; [Particulate Matter co-treated with Acetylcysteine] results in increased expression of NFE2L2 protein; Acetylcysteine affects the reaction [yttrium chloride affects the expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of and affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [aureusidin affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [decamethrin affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [ferrous sulfate affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [triptolide affects the expression of NFE2L2 protein]; Acetylcysteine promotes the reaction [Acrylamide results in increased expression of and affects the localization of NFE2L2 protein]; Acetylcysteine promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]; Sodium Fluoride promotes the reaction [Acetylcysteine affects the localization of NFE2L2 protein] Acetylcysteine affects the reaction [Chlorpyrifos affects the expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [[Sulfasalazine results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Ammonium Chloride results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [dimethoxyethyl phthalate results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids results in increased expression of and affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [flutriafol results in increased localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]]; Acetylcysteine inhibits the reaction [Indomethacin results in increased localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased expression of NFE2L2 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [NFE2L2 protein affects the reaction [Silver results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine inhibits the reaction [NFE2L2 protein affects the susceptibility to Silver]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Polychlorinated Biphenyls analog results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Silver analog results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HSF1 promoter]]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to NQO1 promoter]]; Acetylcysteine inhibits the reaction [sulforaphane affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased phosphorylation of and results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [thymoquinone affects the localization of and results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of NFE2L2 protein] Acetylcysteine results in increased expression of NFE2L2 mRNA Acetylcysteine results in increased expression of NFE2L2 mRNA; Acetylcysteine results in increased expression of NFE2L2 protein Acetylcysteine results in decreased expression of NFE2L2 mRNA |
CTD |
PMID:11909699 PMID:15322212 PMID:16631525 PMID:16806455 PMID:16959797 PMID:17540521 PMID:17959236 PMID:17979524 PMID:17980396 PMID:18156441 PMID:19033392 PMID:19234301 PMID:19350554 PMID:20851755 PMID:21384399 PMID:21643505 PMID:21728338 PMID:21787718 PMID:22019695 PMID:22129741 PMID:22546375 PMID:22564156 PMID:24126012 PMID:24157283 PMID:24355171 PMID:24361488 PMID:24489685 PMID:24634002 PMID:25003661 PMID:25169008 PMID:25263748 PMID:25341683 PMID:25568320 PMID:26079211 PMID:26163453 PMID:26291278 PMID:27867098 PMID:27917510 PMID:28583816 PMID:28807874 PMID:29061315 PMID:29155359 PMID:29426002 PMID:29792947 PMID:29966676 PMID:30104959 PMID:30309986 PMID:30633982 PMID:30742845 PMID:30965051 PMID:31790703 PMID:33797725 PMID:33930485 PMID:34036678 PMID:34200939 PMID:34214916 PMID:34358621 PMID:35088107 PMID:35123993 PMID:35285579 PMID:35430258 PMID:36786954 PMID:36813253 PMID:37257343 PMID:37353053 PMID:37369159 PMID:37598416 PMID:37692514 More...
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NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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G |
Nfil3 |
nuclear factor, interleukin 3, regulated |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NFIL3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109
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G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of NFKB1 protein]] Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of NFKB1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of NFKB1 protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in decreased activity of NFKB1 protein]; Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein]; Acetylcysteine inhibits the reaction [phosphoaspirin results in decreased activity of NFKB1 protein]; Acetylcysteine inhibits the reaction [Sulindac analog results in decreased activity of NFKB1 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of NFKB1 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of NFKB1 protein]; Acetylcysteine inhibits the reaction [Zinc deficiency affects the localization of NFKB1 protein] Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of NFKB1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFKB1 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA] |
CTD |
PMID:11970852 PMID:18922898 PMID:19642688 PMID:21600978 PMID:21741372 PMID:23114885 PMID:24394546 PMID:25845326 PMID:30259999 PMID:31068539 PMID:32402895 More...
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NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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G |
Nfkb2 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKB2 protein]] |
CTD |
PMID:19642688 |
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NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
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G |
Nfkbia |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
multiple interactions decreases degradation affects expression |
EXP ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein] Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in decreased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in increased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [cryptotanshinone results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [piperlongumine analog inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; NFKBIA protein affects the reaction [Acetylcysteine results in decreased susceptibility to hydroxyethyl methacrylate] Acetylcysteine results in decreased degradation of NFKBIA protein Acetylcysteine affects the expression of NFKBIA protein Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased degradation of NFKBIA protein]; Acetylcysteine inhibits the reaction [ferrous sulfate results in increased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:10636889 PMID:10921504 PMID:15949477 PMID:16214328 PMID:18404532 PMID:19176594 PMID:21741372 PMID:25845326 PMID:28583816 PMID:28600121 PMID:31518571 PMID:33030807 PMID:35122928 PMID:35285579 PMID:37369159 PMID:39260547 More...
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NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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G |
Nfkbib |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [oenothein B results in decreased phosphorylation of NFKBIB protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased phosphorylation of NFKBIB protein] |
CTD |
PMID:10381628 PMID:30452899 |
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NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937
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G |
Ngf |
nerve growth factor |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [NGF protein results in increased localization of and results in increased activity of PRKCE protein]; Acetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK3 protein] Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of NGF mRNA] |
CTD |
PMID:16603213 PMID:18375950 PMID:23472850 |
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NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
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G |
Nlgn3 |
neuroligin 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased methylation of NLGN3 promoter]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NLGN3 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NLGN3 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased methylation of NLGN3 promoter] |
CTD |
PMID:27624276 |
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NCBI chr X:100,342,785...100,364,956
Ensembl chr X:100,342,774...100,369,569
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine affects the reaction [diallyl trisulfide results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of NLRP3 mRNA]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of NLRP3 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [piperlongumine results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of and results in decreased ubiquitination of NLRP3 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]] Acetylcysteine results in increased expression of NLRP3 mRNA; Acetylcysteine results in increased expression of NLRP3 protein Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Atrazine results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of NLRP3 protein] Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA] |
CTD |
PMID:24885895 PMID:26086368 PMID:26435000 PMID:26901245 PMID:28004443 PMID:28814068 PMID:30205151 PMID:30259999 PMID:30878009 PMID:30977640 PMID:34217685 PMID:34238121 PMID:34510229 PMID:34791735 PMID:35190838 PMID:36055550 PMID:36347317 PMID:36354081 PMID:36646296 PMID:37300869 PMID:37393521 PMID:37692514 PMID:38242274 PMID:38301994 PMID:38821455 PMID:39260547 More...
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NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
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G |
Nos2 |
nitric oxide synthase 2, inducible |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]]; Acetylcysteine inhibits the reaction [Humic Substances results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Humic Substances results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [mancozeb results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [orazipone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of NOS2 protein] Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [nickel chloride results in decreased expression of NOS2 mRNA] Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [Triglycerides results in decreased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Triglycerides results in decreased expression of NOS2 protein] |
CTD |
PMID:7532384 PMID:9826428 PMID:9918918 PMID:16140881 PMID:18039960 PMID:18830972 PMID:19642688 PMID:21237301 PMID:21741372 PMID:22227475 PMID:23159886 PMID:23268108 PMID:23624824 PMID:23900960 PMID:24239652 PMID:25406100 PMID:30037311 PMID:30259999 PMID:34863858 PMID:37369159 PMID:38513841 PMID:39260547 PMID:39362619 More...
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NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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G |
Nos3 |
nitric oxide synthase 3, endothelial cell |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [[Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of NOS3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Acetylcysteine inhibits the reaction [Triglycerides results in decreased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Triglycerides results in decreased expression of NOS3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]] Acetylcysteine results in increased expression of NOS3 protein Acetylcysteine inhibits the reaction [Aldrin results in increased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [alpha-hexachlorocyclohexane results in increased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in decreased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in decreased expression of NOS3 protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in decreased expression of NOS3 protein]; Acetylcysteine inhibits the reaction [TNF results in decreased expression of NOS3 protein] |
CTD |
PMID:16140881 PMID:17026986 PMID:17321519 PMID:19837105 PMID:21912612 PMID:26906511 PMID:28273962 PMID:31928237 More...
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NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
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G |
Notch2 |
notch 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cypermethrin results in decreased expression of NOTCH2 protein] |
CTD |
PMID:38582279 |
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NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
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G |
Nox1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA] |
CTD |
PMID:16213474 |
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NCBI chr X:132,987,170...133,038,455
Ensembl chr X:132,987,170...133,122,705
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G |
Nox4 |
NADPH oxidase 4 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of NOX4 protein]; Acetylcysteine inhibits the reaction [mancozeb results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of AIF1 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of CS protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of HK2 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of PKM protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [salubrinal results in increased expression of [Cisplatin results in increased expression of NOX4 protein]] Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of NOX4 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of NOX4 protein] |
CTD |
PMID:21131394 PMID:21616140 PMID:24224404 PMID:30037311 PMID:36762617 PMID:39260547 More...
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NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
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G |
Npas2 |
neuronal PAS domain protein 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NPAS2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:39,233,013...39,402,321
Ensembl chr 1:39,232,812...39,402,317
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G |
Npff |
neuropeptide FF-amide peptide precursor |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NPFF mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of NPFF mRNA] |
CTD |
PMID:22129741 |
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NCBI chr15:102,432,274...102,433,056
Ensembl chr15:102,432,274...102,433,377
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G |
Npm1 |
nucleophosmin 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [NPM1 protein mutant form results in increased susceptibility to arsenic trioxide]; Acetylcysteine inhibits the reaction [NPM1 protein mutant form results in increased susceptibility to Bortezomib] |
CTD |
PMID:23877794 |
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NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206
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G |
Npy |
neuropeptide Y |
multiple interactions |
EXP |
Acetylcysteine affects the reaction [bisphenol A affects the expression of NPY mRNA] |
CTD |
PMID:32960947 |
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NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
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G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
multiple interactions increases expression |
ISO EXP |
[Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] which results in decreased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Aspirin analog results in increased activity of NQO1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [flutriafol results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [NQO1 protein results in increased susceptibility to 9,10-phenanthrenequinone]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to NQO1 promoter]]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of NQO1 mRNA]; NQO1 protein promotes the reaction [Acetylcysteine results in decreased susceptibility to 9,10-phenanthrenequinone] [Acetylcysteine co-treated with chromium trioxide] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of NQO1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein]]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased activity of NQO1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of NQO1 mRNA]; Acetylcysteine promotes the reaction [Benzo(a)pyrene results in increased expression of NQO1 protein] [Acetylcysteine co-treated with Sodium Fluoride] results in increased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]; Acetylcysteine promotes the reaction [Sodium Fluoride results in increased expression of NQO1 protein] Acetylcysteine results in increased expression of NQO1 mRNA; Acetylcysteine results in increased expression of NQO1 protein |
CTD |
PMID:12730081 PMID:15044633 PMID:16274885 PMID:16920990 PMID:19033392 PMID:21533816 PMID:21569840 PMID:22129741 PMID:22925602 PMID:23035985 PMID:24489685 PMID:24646717 PMID:25003661 PMID:25341683 PMID:25980575 PMID:26600472 PMID:29108775 PMID:30104959 PMID:30309986 PMID:30633982 PMID:30951941 PMID:31029725 PMID:32525552 PMID:34200939 PMID:35430258 PMID:37353053 PMID:37598416 More...
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NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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G |
Nqo2 |
N-ribosyldihydronicotinamide quinone reductase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [flutriafol results in increased expression of NQO2 mRNA] |
CTD |
PMID:34200939 |
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NCBI chr13:34,148,642...34,172,448
Ensembl chr13:34,148,670...34,172,426
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G |
Nr2e3 |
nuclear receptor subfamily 2, group E, member 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of NR2E3 protein] |
CTD |
PMID:26149760 |
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NCBI chr 9:59,850,054...59,868,117
Ensembl chr 9:59,850,054...59,867,942
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of NR3C1 mRNA Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of NR3C1 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of NR3C1 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of NR3C1 mRNA] |
CTD |
PMID:16084531 PMID:25617244 |
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NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
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G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of NR3C2 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of NR3C2 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA] |
CTD |
PMID:25617244 |
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NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of NRF1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of NRF1 mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of NRF1 mRNA]; Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of NRF1 mRNA] |
CTD |
PMID:21775390 PMID:26980303 PMID:35403558 PMID:36493885 |
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NCBI chr 6:30,047,984...30,153,462
Ensembl chr 6:30,047,987...30,153,457
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G |
Nrxn1 |
neurexin I |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NRXN1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased methylation of NRXN1 promoter]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NRXN1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NRXN1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased methylation of NRXN1 promoter] |
CTD |
PMID:27624276 |
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NCBI chr17:90,341,072...91,400,587
Ensembl chr17:90,341,059...91,400,499
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G |
Ntf3 |
neurotrophin 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of NTF3 protein] |
CTD |
PMID:26138014 |
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NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873
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G |
Nthl1 |
nth (endonuclease III)-like 1 (E.coli) |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of NTHL1 mRNA] |
CTD |
PMID:16137721 |
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NCBI chr17:24,851,656...24,857,812
Ensembl chr17:24,851,654...24,857,811
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G |
Ntrk1 |
neurotrophic tyrosine kinase, receptor, type 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of NTRK1 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased phosphorylation of and results in increased activity of NTRK1 protein] |
CTD |
PMID:23472850 |
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NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
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G |
Ntrk2 |
neurotrophic tyrosine kinase, receptor, type 2 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein] Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in decreased phosphorylation of NTRK2 protein] |
CTD |
PMID:28499986 PMID:38642822 |
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NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
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G |
Nuak2 |
NUAK family, SNF1-like kinase, 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NUAK2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:132,243,827...132,261,233
Ensembl chr 1:132,243,864...132,261,226
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G |
Nupr1 |
nuclear protein transcription regulator 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NUPR1 mRNA Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NUPR1 mRNA] |
CTD |
PMID:22129741 PMID:31319114 |
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NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
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G |
Ocln |
occludin |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of OCLN protein] Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of OCLN mRNA] Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of OCLN protein] |
CTD |
PMID:29235125 PMID:32683294 PMID:32687961 PMID:33485121 PMID:34906888 PMID:37598416 More...
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NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
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G |
Oga |
O-GlcNAcase |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of OGA mRNA |
CTD |
PMID:16084531 |
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NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276
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G |
Olr1 |
oxidized low density lipoprotein (lectin-like) receptor 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein] Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein] |
CTD |
PMID:16055083 PMID:24145059 |
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NCBI chr 6:129,456,113...129,484,312
Ensembl chr 6:129,462,207...129,484,128
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G |
Omg |
oligodendrocyte myelin glycoprotein |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OMG mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:79,391,808...79,394,908
Ensembl chr11:79,391,808...79,394,910
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [15-deoxyprostaglandin J2 results in increased expression of OPA1 protein alternative form]; Acetylcysteine inhibits the reaction [15-deoxyprostaglandin J2 results in increased ubiquitination of OPA1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of OPA1 protein] Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of OPA1 protein] |
CTD |
PMID:20678484 PMID:37084995 PMID:37499777 |
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NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
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G |
Or2ak6 |
olfactory receptor family 2 subfamily AK member 6 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR2AK6 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:58,592,529...58,593,449
Ensembl chr11:58,589,988...58,594,298
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G |
Or4f4b |
olfactory receptor family 4 subfamily F member 4B |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR4F4B mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:111,313,777...111,314,673
Ensembl chr 2:111,311,164...111,314,960
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G |
Or4s2b |
olfactory receptor family 4 subfamily S member 2B |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR4S2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:88,508,201...88,509,157
Ensembl chr 2:88,505,972...88,511,487
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G |
Or51e2 |
olfactory receptor family 51 subfamily E member 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OLR59 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:102,389,928...102,408,678
Ensembl chr 7:102,387,718...102,408,678
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G |
Or51i2 |
olfactory receptor family 51 subfamily I member 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR51I2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:103,689,005...103,689,943
Ensembl chr 7:103,684,652...103,691,279
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G |
Or5as1 |
olfactory receptor family 5 subfamily AS member 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR5AS1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:86,980,064...86,981,003
Ensembl chr 2:86,979,525...86,982,968
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G |
Ormdl3 |
ORM1-like 3 (S. cerevisiae) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ORMDL3 protein] |
CTD |
PMID:27784618 |
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NCBI chr11:98,472,120...98,478,071
Ensembl chr11:98,472,082...98,478,194
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G |
Oser1 |
oxidative stress responsive serine rich 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of OSER1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 2:163,247,742...163,266,422
Ensembl chr 2:163,247,742...163,266,617
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Docosahexaenoic Acids results in increased expression of OSGIN1 protein] |
CTD |
PMID:28807874 |
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NCBI chr 8:120,160,874...120,172,996
Ensembl chr 8:120,160,863...120,172,995
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G |
Otoa |
otoancorin |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OTOA mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:120,682,647...120,762,316
Ensembl chr 7:120,680,873...120,762,320
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G |
P2rx2 |
purinergic receptor P2X, ligand-gated ion channel, 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Acetylcysteine inhibits the reaction [Rotenone promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]] |
CTD |
PMID:19793987 |
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NCBI chr 5:110,487,678...110,491,186
Ensembl chr 5:110,487,678...110,491,078
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G |
P2rx5 |
purinergic receptor P2X, ligand-gated ion channel, 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of P2RX5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:73,029,164...73,063,509
Ensembl chr11:73,051,247...73,063,511
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G |
Pak6 |
p21 (RAC1) activated kinase 6 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PAK6 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:118,493,531...118,528,501
Ensembl chr 2:118,493,784...118,528,501
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G |
Paqr9 |
progestin and adipoQ receptor family member IX |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PAQR9 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:95,441,687...95,450,075
Ensembl chr 9:95,441,710...95,450,076
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G |
Park7 |
Parkinson disease (autosomal recessive, early onset) 7 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased oxidation of PARK7 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased oxidation of PARK7 protein]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Quinones binds to PARK7 protein]]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of PARK7 protein] |
CTD |
PMID:18377993 PMID:20851755 PMID:32540572 PMID:34897981 |
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NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
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G |
Parp1 |
poly (ADP-ribose) polymerase family, member 1 |
increases cleavage multiple interactions decreases expression |
EXP ISO |
Acetylcysteine results in increased cleavage of PARP1 protein Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of PARP1 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of PARP1 protein] [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]; [Acetylcysteine results in increased susceptibility to 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] which results in increased cleavage of PARP1 protein; [Glucose deficiency co-treated with Acetylcysteine] results in increased cleavage of PARP1 protein; Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [4-chromone analog results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[CSC-3436 co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with tanshinone] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [ABBV-744 results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of PARP1 mRNA]; Acetylcysteine inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein]; Acetylcysteine inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [chloropicrin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [divinyl sulfone analog results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [frenolicin B results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [indole-3-carbinol results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [isoliensinine results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [manumycin results in increased cleavage of PARP1]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Morpholines analog results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [osimertinib results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [pendulone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Plant Extracts results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [shikonin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [shogaol results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [sinularin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [tomentosin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [wedelolactone results in increased cleavage of PARP1 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased cleavage of PARP1 protein] Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Gentamicins results in increased activity of PARP1 protein] Acetylcysteine results in decreased expression of PARP1 protein modified form N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of PARP protein in the stomach) |
CTD RGD |
PMID:11470263 PMID:14660655 PMID:14687664 PMID:15375156 PMID:15496615 PMID:17237268 PMID:17309078 PMID:18281123 PMID:18384088 PMID:18703135 PMID:19409983 PMID:19536524 PMID:19679660 PMID:20674558 PMID:20981856 PMID:21031461 PMID:21565247 PMID:22002103 PMID:22172632 PMID:22578287 PMID:22714038 PMID:22733624 PMID:22909951 PMID:22922937 PMID:23082001 PMID:23405080 PMID:23711929 PMID:24036456 PMID:24100277 PMID:24157283 PMID:24373880 PMID:24463199 PMID:24614525 PMID:24634002 PMID:24875536 PMID:25034532 PMID:25246272 PMID:25619640 PMID:25824409 PMID:25845326 PMID:25939952 PMID:25940438 PMID:25972196 PMID:26203587 PMID:26219228 PMID:26887594 PMID:27106530 PMID:27539140 PMID:27634458 PMID:27658547 PMID:28087840 PMID:28237877 PMID:28548367 PMID:28918123 PMID:29111403 PMID:29111459 PMID:29248572 PMID:29479036 PMID:29774349 PMID:29800641 PMID:29944906 PMID:30256521 PMID:30408460 PMID:30661989 PMID:30796935 PMID:30871965 PMID:30917517 PMID:31157515 PMID:31313457 PMID:31330229 PMID:31408635 PMID:31433961 PMID:31884112 PMID:32662599 PMID:33002460 PMID:33118390 PMID:33971260 PMID:34599545 PMID:34627931 PMID:35288263 PMID:35396826 PMID:36070022 PMID:37072049 PMID:37769529 PMID:38042493 PMID:38521250 PMID:29408335 More...
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RGD:127284846 |
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1, cytosolic |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Malathion results in increased expression of PCK1 mRNA] |
CTD |
PMID:25449180 |
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NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
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G |
Pcmt1 |
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dopamine results in decreased expression of PCMT1 mRNA]; Acetylcysteine inhibits the reaction [Dopamine results in decreased expression of PCMT1 protein] |
CTD |
PMID:24631677 |
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NCBI chr10:7,503,608...7,556,922
Ensembl chr10:7,505,137...7,556,900
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of PCNA protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of PCNA protein] Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of PCNA protein] |
CTD |
PMID:31551408 PMID:33485121 PMID:33797725 |
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NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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G |
Pdcd4 |
programmed cell death 4 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[tungsten carbide analog co-treated with Cobalt analog] results in decreased expression of PDCD4 protein] Acetylcysteine inhibits the reaction [chromium hexavalent ion results in decreased expression of PDCD4 mRNA] |
CTD |
PMID:23758151 PMID:27323401 |
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NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291
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G |
Pdcd6ip |
programmed cell death 6 interacting protein |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [hesperetin results in decreased expression of PDCD6IP protein] |
CTD |
PMID:37487865 |
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NCBI chr 9:113,480,812...113,537,457
Ensembl chr 9:113,480,812...113,537,327
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G |
Pde6b |
phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PDE6B mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:108,536,239...108,579,609
Ensembl chr 5:108,536,257...108,580,263
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G |
Pdgfb |
platelet derived growth factor, B polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]] Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PDGFB protein] |
CTD |
PMID:22700867 PMID:26138014 |
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NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
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G |
Pdgfrb |
platelet derived growth factor receptor, beta polypeptide |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of PDGFRB mRNA] Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB mRNA]]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB protein]] |
CTD |
PMID:21134390 PMID:23392711 |
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NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
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G |
Pdha1 |
pyruvate dehydrogenase E1 alpha 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 mRNA]; Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 protein] |
CTD |
PMID:31857147 |
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NCBI chr X:158,905,215...158,921,426
Ensembl chr X:158,905,205...158,921,409
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G |
Pdk1 |
pyruvate dehydrogenase kinase, isoenzyme 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PDK1 mRNA]; Acetylcysteine inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of PDK1 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDK1 mRNA]; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased expression of PDK1 mRNA] |
CTD |
PMID:17171638 PMID:30821169 PMID:31251971 PMID:31724279 |
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NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
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G |
Pdk4 |
pyruvate dehydrogenase kinase, isoenzyme 4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PDK4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
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G |
Pdlim5 |
PDZ and LIM domain 5 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of PDLIM5 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 3:141,945,346...142,101,480
Ensembl chr 3:141,945,351...142,101,454
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G |
Pex11a |
peroxisomal biogenesis factor 11 alpha |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PEX11A mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PEX11A mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 7:79,385,705...79,392,879
Ensembl chr 7:79,385,705...79,392,879
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G |
Pgd |
phosphogluconate dehydrogenase |
increases activity |
ISO |
Acetylcysteine results in increased activity of PGD protein |
CTD |
PMID:3099627 |
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NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
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G |
Pgr |
progesterone receptor |
multiple interactions decreases secretion |
ISO EXP |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of PGR mRNA] Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of PGR mRNA]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased secretion of PGR protein] Acetylcysteine results in decreased secretion of PGR protein |
CTD |
PMID:18829485 PMID:21220312 PMID:30648648 |
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NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
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G |
Piga |
phosphatidylinositol glycan anchor biosynthesis, class A |
increases expression |
ISO |
Acetylcysteine results in increased expression of PIGA mRNA |
CTD |
PMID:16084531 |
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NCBI chr X:163,202,814...163,216,912
Ensembl chr X:163,202,783...163,216,912
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in decreased phosphorylation of PIK3R1 protein]; Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of PIK3R1 protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of TNF protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]] |
CTD |
PMID:28836394 PMID:37751786 PMID:38521250 |
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NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
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G |
Pim1 |
proviral integration site 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PIM1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr17:29,709,759...29,715,085
Ensembl chr17:29,709,727...29,715,086
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G |
Pim2 |
proviral integration site 2 |
increases expression |
ISO |
Acetylcysteine results in increased expression of PIM2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr X:7,744,545...7,749,671
Ensembl chr X:7,744,501...7,749,671
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G |
Pink1 |
PTEN induced putative kinase 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PINK1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PINK1]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PINK1 protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased expression of PINK1 protein] Acetylcysteine inhibits the reaction [quinone results in increased expression of PINK1 protein] Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PINK1 mRNA]; Acetylcysteine inhibits the reaction [Lead results in increased expression of PINK1 mRNA] |
CTD |
PMID:25464205 PMID:29567065 PMID:34547296 PMID:34816377 PMID:37678662 PMID:37692514 More...
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NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
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G |
Pip |
prolactin induced protein |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PIP mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:41,824,483...41,828,999
Ensembl chr 6:41,824,469...41,828,999
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G |
Pirb |
paired Ig-like receptor B |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LILRB3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:3,715,504...3,723,381
Ensembl chr 7:3,714,408...3,723,390
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G |
Piwil4 |
piwi-like RNA-mediated gene silencing 4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PIWIL4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:14,613,072...14,651,968
Ensembl chr 9:14,607,526...14,652,036
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G |
Pkm |
pyruvate kinase, muscle |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of PKM protein]]; Acetylcysteine inhibits the reaction [quinone results in increased degradation of PKM protein] Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PKM mRNA]; Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PKM protein]; Acetylcysteine inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of PKM protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; Acetylcysteine inhibits the reaction [DDT results in increased expression of and affects the localization of PKM protein alternative form]; Acetylcysteine inhibits the reaction [DDT results in increased expression of PKM mRNA alternative form]; Acetylcysteine inhibits the reaction [icaritin results in decreased expression of PKM protein] |
CTD |
PMID:25437431 PMID:28284859 PMID:30821169 PMID:31251971 PMID:31724279 PMID:36762617 PMID:38431053 More...
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NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
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G |
Pla2g4a |
phospholipase A2, group IVA (cytosolic, calcium-dependent) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Ditiocarb results in increased expression of PLA2G4A mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of PLA2G4A mRNA] |
CTD |
PMID:15683734 PMID:16603213 |
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NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
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G |
Plau |
plasminogen activator, urokinase |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of PLAU mRNA Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased secretion of PLAU protein] |
CTD |
PMID:15962302 PMID:16084531 |
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NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
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G |
Plaur |
plasminogen activator, urokinase receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Nicotine results in increased expression of PLAUR mRNA] |
CTD |
PMID:22261521 |
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NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
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G |
Pld1 |
phospholipase D1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]] |
CTD |
PMID:17640750 |
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NCBI chr 3:27,992,636...28,187,388
Ensembl chr 3:27,992,844...28,187,511
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G |
Pld2 |
phospholipase D2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [PLD2 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]] |
CTD |
PMID:17640750 |
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NCBI chr11:70,430,318...70,448,936
Ensembl chr11:70,430,890...70,448,936
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G |
Plin2 |
perilipin 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PLIN2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
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G |
Plppr1 |
phospholipid phosphatase related 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PLPPR1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:49,054,986...49,340,261
Ensembl chr 4:49,059,273...49,340,259
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2-xylene results in increased expression of PMAIP1 mRNA]; Acetylcysteine inhibits the reaction [Benzene results in increased expression of PMAIP1 mRNA]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of PMAIP1 mRNA]; Acetylcysteine inhibits the reaction [Toluene results in increased expression of PMAIP1 mRNA] |
CTD |
PMID:18723479 PMID:21144877 |
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NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
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G |
Pnpla3 |
patatin-like phospholipase domain containing 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dietary Fats results in increased expression of PNPLA3 mRNA] |
CTD |
PMID:21051528 |
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NCBI chr15:84,052,017...84,073,720
Ensembl chr15:84,052,038...84,071,437
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G |
Pnpla5 |
patatin-like phospholipase domain containing 5 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PNPLA5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:83,996,631...84,007,567
Ensembl chr15:83,996,557...84,007,376
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G |
Pnrc1 |
proline-rich nuclear receptor coactivator 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PNRC1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:33,245,423...33,248,787
Ensembl chr 4:33,245,423...33,290,163
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G |
Polr1c |
polymerase (RNA) I polypeptide C |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Paraquat results in decreased methylation of POLR1C mRNA] |
CTD |
PMID:34425375 |
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NCBI chr17:46,554,846...46,558,971
Ensembl chr17:46,554,846...46,558,980
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G |
Pomc |
pro-opiomelanocortin-alpha |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [POMC protein promotes the reaction [cobaltous chloride results in increased activity of CASP3 protein]] |
CTD |
PMID:24412703 |
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NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
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G |
Pon1 |
paraoxonase 1 |
multiple interactions |
ISO |
Acetylcysteine affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PON1 protein] |
CTD |
PMID:23644946 |
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NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
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G |
Pon2 |
paraoxonase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of PON2 protein] |
CTD |
PMID:17916643 |
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NCBI chr 6:5,264,620...5,298,408
Ensembl chr 6:5,264,147...5,298,455
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G |
Postn |
periostin, osteoblast specific factor |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of POSTN mRNA |
CTD |
PMID:32947957 |
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NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
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G |
Pou5f1 |
POU domain, class 5, transcription factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [decabromobiphenyl ether results in decreased expression of POU5F1 protein]; Acetylcysteine inhibits the reaction [ovatodiolide results in decreased expression of POU5F1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of POU5F1 protein] |
CTD |
PMID:26206603 PMID:32745510 PMID:39276908 |
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NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
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G |
Pparg |
peroxisome proliferator activated receptor gamma |
increases expression multiple interactions |
ISO EXP |
Acetylcysteine results in increased expression of PPARG mRNA; Acetylcysteine results in increased expression of PPARG protein Acetylcysteine inhibits the reaction [yttrium chloride results in decreased expression of PPARG protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of PPARG mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of PPARG protein] Acetylcysteine inhibits the reaction [[[15-deoxyprostaglandin J2 results in increased activity of PPARG protein] which results in decreased expression of SOD2 protein] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein] Acetylcysteine inhibits the reaction [[Carbon Monoxide results in increased abundance of Reactive Oxygen Species] which results in increased sumoylation of PPARG protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of PPARG protein] |
CTD |
PMID:16945329 PMID:17602960 PMID:22046279 PMID:23964924 PMID:27117918 PMID:35088107 More...
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NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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G |
Ppargc1a |
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Flavonoids results in increased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of PPARGC1A protein] Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of PPARGC1A mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1A mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of PPARGC1A mRNA]; Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of PPARGC1A mRNA] |
CTD |
PMID:21775390 PMID:23063593 PMID:26980303 PMID:30104959 PMID:30641872 PMID:35403558 PMID:36493885 PMID:37084995 PMID:39260547 More...
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NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
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G |
Ppargc1b |
peroxisome proliferative activated receptor, gamma, coactivator 1 beta |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1B mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1B protein] |
CTD |
PMID:36493885 |
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NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502
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G |
Ppbp |
pro-platelet basic protein |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Cadmium Chloride results in decreased secretion of PPBP protein] |
CTD |
PMID:26138014 |
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NCBI chr 5:90,916,377...90,917,922
Ensembl chr 5:90,916,377...90,917,922
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G |
Ppm1a |
protein phosphatase 1A, magnesium dependent, alpha isoform |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of PPM1A protein] |
CTD |
PMID:39197814 |
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NCBI chr12:72,804,231...72,846,593
Ensembl chr12:72,804,229...72,846,593
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of PPP1R15A mRNA] Acetylcysteine inhibits the reaction [arsenite promotes the reaction [TARDBP protein binds to PPP1R15A protein]] |
CTD |
PMID:24291486 PMID:29109149 |
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NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
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G |
Ppp2ca |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased methylation of and results in increased phosphorylation of PPP2CA protein] |
CTD |
PMID:18703135 |
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NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
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G |
Ppp2r1b |
protein phosphatase 2, regulatory subunit A, beta |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPP2R1B protein] |
CTD |
PMID:18703135 |
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NCBI chr 9:50,767,946...50,810,625
Ensembl chr 9:50,756,601...50,805,529
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G |
Ppp5c |
protein phosphatase 5, catalytic subunit |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPP5C protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPP5C protein] |
CTD |
PMID:18703135 PMID:19038359 |
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NCBI chr 7:16,738,575...16,761,812
Ensembl chr 7:16,738,565...16,761,849
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G |
Prdx1 |
peroxiredoxin 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[frenolicin B results in decreased activity of PRDX1 protein] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [indole-3-carbinol results in decreased expression of PRDX1 protein] |
CTD |
PMID:30661989 PMID:33118390 |
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NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
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G |
Prdx3 |
peroxiredoxin 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Thiostrepton affects the expression of PRDX3 protein modified form] |
CTD |
PMID:22761781 |
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NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994
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G |
Prdx5 |
peroxiredoxin 5 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [PRKAA2 protein affects the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of PRDX5 protein]] |
CTD |
PMID:29753072 |
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NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474
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G |
Prh1 |
proline rich protein HaeIII subfamily 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PRH1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:132,546,805...132,549,364
Ensembl chr 6:132,546,772...132,549,904
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G |
Prkaa1 |
protein kinase, AMP-activated, alpha 1 catalytic subunit |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased phosphorylation of PRKAA1 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased phosphorylation of PRKAA1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of PRKAA1 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of PRKAA1 mRNA]; Acetylcysteine inhibits the reaction [Quercetin results in increased phosphorylation of and results in increased activity of PRKAA1 protein]; Acetylcysteine inhibits the reaction [Quercetin results in increased phosphorylation of PRKAA1 protein]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased phosphorylation of PRKAA1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in decreased phosphorylation of PRKAA1 protein] |
CTD |
PMID:19293639 PMID:20083342 PMID:21195169 PMID:24386346 PMID:24535669 PMID:31900833 PMID:36534932 PMID:39260547 More...
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NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
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G |
Prkaa2 |
protein kinase, AMP-activated, alpha 2 catalytic subunit |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[PRKAA2 protein affects the susceptibility to [Air Pollutants results in increased abundance of Particulate Matter]] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased phosphorylation of PRKAA2 protein]; Acetylcysteine inhibits the reaction [PRKAA2 protein affects the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of PRDX5 protein]]; Acetylcysteine inhibits the reaction [PRKAA2 protein affects the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of TNF protein]] |
CTD |
PMID:29753072 PMID:39260547 |
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NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087
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G |
Prkcd |
protein kinase C, delta |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein]; Acetylcysteine inhibits the reaction [Ursodeoxycholic Acid results in increased localization of PRKCD protein] Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of PRKCD protein] Acetylcysteine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of and results in increased phosphorylation of PRKCD protein] |
CTD |
PMID:17171638 PMID:21362627 PMID:27658547 PMID:37308051 |
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NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
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G |
Prkce |
protein kinase C, epsilon |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [NGF protein results in increased localization of and results in increased activity of PRKCE protein] |
CTD |
PMID:18375950 |
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NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
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G |
Prkdc |
protein kinase, DNA activated, catalytic polypeptide |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of PRKDC protein Acetylcysteine inhibits the reaction [usnic acid results in increased expression of PRKDC protein] |
CTD |
PMID:31715134 |
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NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PRKN]; Acetylcysteine inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of PRKN mRNA] Acetylcysteine inhibits the reaction [quinone results in increased expression of PRKN protein] Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PRKN mRNA]; Acetylcysteine inhibits the reaction [Lead results in increased expression of PRKN mRNA] |
CTD |
PMID:22872702 PMID:25464205 PMID:29567065 PMID:31368586 PMID:34547296 PMID:34816377 More...
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NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
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G |
Prl |
prolactin |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased secretion of PRL protein] |
CTD |
PMID:27151894 |
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NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
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G |
Prl2c2 |
prolactin family 2, subfamily c, member 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Asbestos, Amosite results in increased expression of PRL2C2 mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of PRL2C2 mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased expression of PRL2C2 mRNA] |
CTD |
PMID:9006111 |
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NCBI chr13:13,170,705...13,179,978
Ensembl chr13:13,170,710...13,179,968
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G |
Prlr |
prolactin receptor |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PRLR mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PRLR mRNA] |
CTD |
PMID:22129741 |
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NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266
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G |
Psat1 |
phosphoserine aminotransferase 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PSAT1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PSAT1 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701
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G |
Psmd1 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Paraquat results in decreased methylation of PSMD1 mRNA] |
CTD |
PMID:34425375 |
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NCBI chr 1:85,992,341...86,067,017
Ensembl chr 1:85,992,109...86,066,873
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G |
Psme4 |
proteasome (prosome, macropain) activator subunit 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of PSME4 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr11:30,721,753...30,831,150
Ensembl chr11:30,721,726...30,830,361
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G |
Pten |
phosphatase and tensin homolog |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of PTEN mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [PTEN gene mutant form results in increased secretion of GPT protein]] |
CTD |
PMID:21195169 PMID:24449419 PMID:27022031 PMID:35430258 |
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NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression multiple interactions |
ISO EXP |
Acetylcysteine results in decreased expression of PTGS2 mRNA Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of PTGS2 protein] Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased expression of PTGS2 mRNA] which results in increased abundance of Dinoprostone]; Acetylcysteine inhibits the reaction [benzanthrone results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2]; Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Humic Substances results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Humic Substances results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [JP8 aviation fuel results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of PTGS2 protein]; Acetylcysteine promotes the reaction [3-methylquercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]] Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [[Formaldehyde co-treated with eugenol, zinc oxide dental cavity lining] results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [[IL1B protein co-treated with Oligomycins] results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Antimony results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Benzene results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of PTGS2 mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of PTGS2 protein]]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride affects the localization of PTGS2 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [dentinol results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Estradiol promotes the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; Acetylcysteine inhibits the reaction [PLD2 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Styrene results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Toluene results in increased expression of PTGS2 protein]; Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of PTGS2 mRNA] |
CTD |
PMID:14687664 PMID:15576159 PMID:15934011 PMID:16024921 PMID:16084531 PMID:16777358 PMID:17082565 PMID:17255567 PMID:17640750 PMID:18068289 PMID:18480072 PMID:19084589 PMID:19095747 PMID:19642688 PMID:21220312 PMID:21533553 PMID:21540248 PMID:21703343 PMID:21779360 PMID:21801798 PMID:22288910 PMID:22767315 PMID:23268108 PMID:24239652 PMID:24337631 PMID:24609059 PMID:24793810 PMID:24961358 PMID:24967690 PMID:25199686 PMID:28495310 PMID:28495615 PMID:28555929 PMID:29248572 PMID:29753051 PMID:29894800 PMID:31068539 PMID:32525552 PMID:33437163 PMID:37422542 PMID:38097005 PMID:38513841 More...
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NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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G |
Ptk2 |
PTK2 protein tyrosine kinase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein] |
CTD |
PMID:17888894 |
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NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
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G |
Ptk2b |
PTK2 protein tyrosine kinase 2 beta |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [TNF protein results in decreased phosphorylation of PTK2B protein] |
CTD |
PMID:23774252 |
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NCBI chr14:66,390,706...66,518,549
Ensembl chr14:66,390,706...66,518,501
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G |
Ptk6 |
PTK6 protein tyrosine kinase 6 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PTK6 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:180,836,917...180,845,408
Ensembl chr 2:180,835,514...180,844,582
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G |
Ptpn1 |
protein tyrosine phosphatase, non-receptor type 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]; Acetylcysteine inhibits the reaction [Pamidronate promotes the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]; Acetylcysteine inhibits the reaction [Pyruvaldehyde results in increased expression of PTPN1 protein] |
CTD |
PMID:22917016 PMID:32337366 |
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NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305
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G |
Pycard |
PYD and CARD domain containing |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of PYCARD protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [piperlongumine results in increased expression of PYCARD protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of PYCARD protein]] Acetylcysteine results in increased expression of PYCARD protein |
CTD |
PMID:26079697 PMID:26435000 PMID:30977640 PMID:34791735 PMID:36055550 PMID:36646296 PMID:38242274 More...
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NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
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G |
Pygl |
liver glycogen phosphorylase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Malathion results in increased expression of PYGL mRNA] |
CTD |
PMID:25449180 |
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NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262
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G |
Rab24 |
RAB24, member RAS oncogene family |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of RAB24 protein] |
CTD |
PMID:16137721 |
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NCBI chr13:55,467,036...55,469,807
Ensembl chr13:55,467,556...55,469,759
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G |
Rab30 |
RAB30, member RAS oncogene family |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RAB30 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RAB30 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 7:92,390,845...92,493,743
Ensembl chr 7:92,390,811...92,493,743
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G |
Rab7 |
RAB7, member RAS oncogene family |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]] |
CTD |
PMID:28347754 |
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NCBI chr 6:87,976,088...88,022,252
Ensembl chr 6:87,976,088...88,022,252
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G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of RAC1 protein] Acetylcysteine results in decreased expression of RAC1 protein |
CTD |
PMID:21195169 |
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NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
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G |
Rac2 |
Rac family small GTPase 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Resveratrol affects the localization of RAC2 protein] |
CTD |
PMID:37482209 |
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NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983
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G |
Rack1 |
receptor for activated C kinase 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of RACK1 mRNA] |
CTD |
PMID:36315628 |
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NCBI chr11:48,691,187...48,697,068
Ensembl chr11:48,691,159...48,697,261
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G |
Rad1 |
RAD1 checkpoint DNA exonuclease |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of RAD1 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr15:10,486,104...10,499,149
Ensembl chr15:10,486,104...10,499,149
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G |
Rad18 |
RAD18 E3 ubiquitin protein ligase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [4-biphenylamine results in decreased expression of RAD18 protein] |
CTD |
PMID:32433928 |
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NCBI chr 6:112,596,812...112,673,650
Ensembl chr 6:112,596,811...112,673,647
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G |
Rad51b |
RAD51 paralog B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of RAD51B mRNA] |
CTD |
PMID:33971260 |
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NCBI chr12:79,344,032...79,895,034
Ensembl chr12:79,344,056...79,861,464
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G |
Rad54l |
RAD54 like (S. cerevisiae) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of RAD54L mRNA] |
CTD |
PMID:35430258 |
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NCBI chr 4:115,951,458...115,980,875
Ensembl chr 4:115,951,461...115,980,887
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G |
Rad9a |
RAD9 checkpoint clamp component A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of RAD9A mRNA] |
CTD |
PMID:33971260 |
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NCBI chr19:4,245,195...4,251,710
Ensembl chr19:4,245,195...4,251,661
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G |
Raf1 |
v-raf-leukemia viral oncogene 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [NSC 680410 results in decreased expression of RAF1 protein] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of RAF1 mRNA Acetylcysteine inhibits the reaction [tubocapsenolide A results in increased degradation of RAF1 protein] |
CTD |
PMID:16481037 PMID:18442981 PMID:22129741 |
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NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
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G |
Rb1 |
RB transcriptional corepressor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of RB1 protein modified form]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased phosphorylation of RB1 protein]; Acetylcysteine inhibits the reaction [Levamisole results in decreased expression of RB1 protein] Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of RB1 mRNA]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of RB1 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of RB1 mRNA] |
CTD |
PMID:11139434 PMID:16497787 PMID:22927544 PMID:29859004 |
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NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
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G |
Rel |
reticuloendotheliosis oncogene |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Lipopolysaccharides affects the localization of REL protein] Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of REL protein] |
CTD |
PMID:11970852 PMID:23114885 |
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NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970
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G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
multiple interactions increases glutathionylation increases activity decreases phosphorylation increases phosphorylation |
EXP ISO |
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [[PRKAA2 protein affects the susceptibility to [Air Pollutants results in increased abundance of Particulate Matter]] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [endotoxin, Escherichia coli affects the localization of and results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [JP8 aviation fuel results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA mRNA]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; Acetylcysteine promotes the reaction [Particulate Matter results in decreased phosphorylation of RELA protein] Acetylcysteine results in increased glutathionylation of RELA protein Acetylcysteine results in increased activity of RELA protein [Acetylcysteine co-treated with oenothein B] results in decreased phosphorylation of RELA protein; [Acetylcysteine co-treated with TNF protein] results in decreased activity of RELA protein; Acetylcysteine affects the localization of and results in increased activity of RELA protein; Acetylcysteine affects the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of RELA protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [APP protein affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Chloroquine results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [chrysin results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [cryptotanshinone affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Fenbendazole analog results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Fenbendazole results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate affects the localization of and results in decreased activity of RELA protein]; Acetylcysteine inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased phosphorylation of RELA protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [mancozeb affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [ovatodiolide results in decreased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Particulate Matter affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased acetylation of RELA protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester) affects the expression of RELA protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased activity of RELA protein] Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of and results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of and affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [ferrous sulfate affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [RELA protein binds to MMP9 promoter]; Acetylcysteine inhibits the reaction [Smoke affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein affects the localization of RELA protein] Acetylcysteine results in decreased phosphorylation of RELA protein Acetylcysteine results in increased phosphorylation of RELA protein |
CTD |
PMID:7491977 PMID:8760145 PMID:11970852 PMID:15139008 PMID:17925309 PMID:18457675 PMID:19095747 PMID:19176594 PMID:19281832 PMID:19608869 PMID:19760616 PMID:20116392 PMID:20351055 PMID:21533553 PMID:21741372 PMID:22664789 PMID:22704995 PMID:23114885 PMID:23755222 PMID:23774252 PMID:24961358 PMID:25845326 PMID:25876056 PMID:25972196 PMID:27235710 PMID:27393034 PMID:28004443 PMID:28115242 PMID:28495310 PMID:28583816 PMID:28600121 PMID:29087013 PMID:29329563 PMID:29426002 PMID:29753072 PMID:30452899 PMID:31068539 PMID:32687961 PMID:34171359 PMID:34310962 PMID:34510229 PMID:34890707 PMID:35122928 PMID:35190838 PMID:35285579 PMID:35349355 PMID:35569513 PMID:36055550 PMID:36343683 PMID:36646296 PMID:36786954 PMID:36880428 PMID:37369159 PMID:37393521 PMID:37598416 PMID:39260547 PMID:39276908 More...
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NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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G |
Relb |
avian reticuloendotheliosis viral (v-rel) oncogene related B |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein] Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELB protein]] |
CTD |
PMID:11970852 PMID:19642688 |
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NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
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G |
Ren1 |
renin 1 structural |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [ioxitalamic acid results in increased expression of REN protein] |
CTD |
PMID:19945959 |
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NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063
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G |
Rgs16 |
regulator of G-protein signaling 16 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RGS16 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214
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G |
Rhobtb1 |
Rho-related BTB domain containing 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of RHOBTB1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr10:68,987,106...69,127,621
Ensembl chr10:68,987,264...69,127,621
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G |
Ripk1 |
receptor (TNFRSF)-interacting serine-threonine kinase 1 |
multiple interactions |
EXP ISO |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of RIPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of RIPK1 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of RIPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of RIPK1 protein]]; Acetylcysteine affects the reaction [Benzo(a)pyrene affects the expression of RIPK1 protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK1 protein] Acetylcysteine inhibits the reaction [3-monochloropropane-1, 2 diol ester results in increased expression of RIPK1 protein]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of RIPK1 mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of RIPK1 protein]] |
CTD |
PMID:35777681 PMID:35833596 PMID:37422542 PMID:37678662 PMID:38408632 |
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NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
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G |
Ripk2 |
receptor (TNFRSF)-interacting serine-threonine kinase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of RIPK2 mRNA] |
CTD |
PMID:19477266 |
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NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647
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G |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
multiple interactions |
EXP ISO |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of RIPK3 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of RIPK3 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of RIPK3 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of RIPK3 protein]]; Acetylcysteine affects the reaction [Benzo(a)pyrene affects the expression of RIPK3 protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK3 protein] Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of RIPK3 protein] Acetylcysteine inhibits the reaction [3-monochloropropane-1, 2 diol ester results in increased expression of RIPK3 protein]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of RIPK3 mRNA]]; Acetylcysteine inhibits the reaction [bisphenol A promotes the reaction [Selenium deficiency results in increased expression of RIPK3 protein]] |
CTD |
PMID:35777681 PMID:35833596 PMID:36000575 PMID:37422542 PMID:37678662 PMID:38408632 More...
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NCBI chr14:56,022,452...56,026,314
Ensembl chr14:56,022,452...56,026,322
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G |
Rnase2a |
ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin) |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RNASE2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:51,492,718...51,493,569
Ensembl chr14:51,492,719...51,493,569
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G |
Rnf125 |
ring finger protein 125 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RNF125 mRNA |
CTD |
PMID:22129741 |
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NCBI chr18:21,077,672...21,120,416
Ensembl chr18:21,077,682...21,116,919
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G |
Rora |
RAR-related orphan receptor alpha |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RORA mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:68,560,627...69,295,528
Ensembl chr 9:68,561,068...69,295,528
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G |
Rps6kb1 |
ribosomal protein S6 kinase, polypeptide 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein] Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:14516795 PMID:18569013 PMID:21195169 PMID:24299490 PMID:26804764 PMID:31982503 More...
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NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
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G |
Rtp1 |
receptor transporter protein 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RTP1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RTP1 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr16:23,247,883...23,252,710
Ensembl chr16:23,247,883...23,252,710
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G |
Runx2 |
runt related transcription factor 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of RUNX2 mRNA] Acetylcysteine inhibits the reaction [Dexamethasone affects the expression of RUNX2 mRNA] |
CTD |
PMID:19017541 PMID:24239970 |
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NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
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G |
Rxra |
retinoid X receptor alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of RXRA mRNA] |
CTD |
PMID:18829485 |
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NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
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G |
S100a11 |
S100 calcium binding protein A11 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein] |
CTD |
PMID:25940438 |
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NCBI chr 3:93,427,803...93,433,595
Ensembl chr 3:93,427,795...93,433,594
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G |
S100a4 |
S100 calcium binding protein A4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dietary Fats results in increased expression of S100A4 mRNA] |
CTD |
PMID:21051528 |
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NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352
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G |
S100a9 |
S100 calcium binding protein A9 (calgranulin B) |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of S100A9 protein] |
CTD |
PMID:32924446 |
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NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
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G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SAT1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr X:153,996,128...153,999,345
Ensembl chr X:153,996,128...153,999,445
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G |
Scd1 |
stearoyl-Coenzyme A desaturase 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SCD1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
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G |
Sec31a |
SEC31 homolog A, COPII coat complex component |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of SEC31A mRNA] |
CTD |
PMID:34425375 |
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NCBI chr 5:100,509,508...100,564,132
Ensembl chr 5:100,509,508...100,564,093
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G |
Sele |
selectin, endothelial cell |
decreases expression multiple interactions |
ISO EXP |
Acetylcysteine results in decreased expression of SELE mRNA Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SELE protein]] Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein] |
CTD |
PMID:16084531 PMID:19642688 PMID:26901245 |
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NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
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G |
Selenoi |
selenoprotein I |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SELENOI mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:30,437,579...30,477,428
Ensembl chr 5:30,437,579...30,477,425
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G |
Serpinh1 |
serine (or cysteine) peptidase inhibitor, clade H, member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SERPINH1 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SERPINH1 protein] |
CTD |
PMID:13679210 |
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NCBI chr 7:98,994,583...99,002,321
Ensembl chr 7:98,994,583...99,002,446
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G |
Sesn2 |
sestrin 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of SESN2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of SESN2 protein]; Acetylcysteine inhibits the reaction [erastin results in increased expression of SESN2 protein]; Acetylcysteine inhibits the reaction [Hemin results in increased expression of SESN2 protein]; Acetylcysteine inhibits the reaction [Quercetin results in increased expression of SESN2 protein] |
CTD |
PMID:24535669 PMID:29662624 PMID:31054940 PMID:31323261 |
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NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SFRP2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:83,673,628...83,681,621
Ensembl chr 3:83,673,628...83,681,623
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G |
Sftpa1 |
surfactant associated protein A1 |
multiple interactions |
EXP ISO |
Acetylcysteine affects the reaction [Particulate Matter affects the expression of SFTPA1 protein] Acetylcysteine inhibits the reaction [Silicon Dioxide results in decreased expression of SFTPA1 protein] |
CTD |
PMID:31449845 PMID:35689653 |
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NCBI chr14:40,853,745...40,858,330
Ensembl chr14:40,853,739...40,858,409
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G |
Sftpb |
surfactant associated protein B |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Silicon Dioxide results in decreased expression of SFTPB protein] Acetylcysteine inhibits the reaction [[Air Pollutants, Occupational results in increased abundance of Particulate Matter] which results in decreased expression of SFTPB protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of SFTPB protein] Acetylcysteine results in increased expression of SFTPB protein |
CTD |
PMID:27208422 PMID:35689653 |
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NCBI chr 6:72,281,594...72,291,354
Ensembl chr 6:72,281,594...72,291,354
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G |
Sftpc |
surfactant associated protein C |
increases expression multiple interactions |
EXP |
Acetylcysteine results in increased expression of SFTPC protein Acetylcysteine inhibits the reaction [[Air Pollutants, Occupational results in increased abundance of Particulate Matter] which results in decreased expression of SFTPC protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of SFTPC protein] |
CTD |
PMID:27208422 |
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NCBI chr14:70,758,381...70,761,521
Ensembl chr14:70,758,389...70,761,521
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G |
Shc1 |
src homology 2 domain-containing transforming protein C1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [SHC1 protein results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in increased expression of VIM protein] Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased phosphorylation of SHC1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of SHC1 protein] |
CTD |
PMID:32659284 PMID:33360347 |
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NCBI chr 3:89,325,858...89,337,336
Ensembl chr 3:89,325,750...89,337,334
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G |
Shisa2 |
shisa family member 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SHISA2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:59,862,730...59,869,109
Ensembl chr14:59,862,757...59,869,109
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G |
Sirt1 |
sirtuin 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of SIRT1 protein] Acetylcysteine inhibits the reaction [[nonylphenol co-treated with octylphenol] results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of SIRT1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SIRT1 protein] |
CTD |
PMID:21031461 PMID:30055241 PMID:33360347 PMID:36493885 PMID:38642822 PMID:39260547 More...
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NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
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G |
Sirt3 |
sirtuin 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SIRT3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 protein] Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SIRT3 mRNA] |
CTD |
PMID:30104959 PMID:30641872 PMID:35430258 |
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NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222
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G |
Sla2 |
Src-like-adaptor 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLA2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:156,716,071...156,729,161
Ensembl chr 2:156,714,377...156,729,112
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G |
Slc12a1 |
solute carrier family 12, member 1 |
increases expression |
ISO |
Acetylcysteine results in increased expression of SLC12A1 protein |
CTD |
PMID:23183129 |
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NCBI chr 2:124,994,430...125,071,922
Ensembl chr 2:124,994,425...125,071,922
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G |
Slc12a3 |
solute carrier family 12, member 3 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC12A3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:95,055,737...95,092,850
Ensembl chr 8:95,055,829...95,092,842
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G |
Slc14a2 |
solute carrier family 14 (urea transporter), member 2 |
multiple interactions increases expression |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC14A2 mRNA Acetylcysteine results in increased expression of SLC14A2 protein |
CTD |
PMID:22129741 PMID:23183129 |
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NCBI chr18:78,189,359...78,640,165
Ensembl chr18:78,189,363...78,640,157
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G |
Slc19a2 |
solute carrier family 19 (thiamine transporter), member 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SLC19A2 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 1:164,076,615...164,092,954
Ensembl chr 1:164,076,615...164,092,954
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G |
Slc1a1 |
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
multiple interactions |
EXP |
Acetylcysteine affects the reaction [SLC1A1 protein affects the transport of Zinc]; Acetylcysteine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine affects the localization of SLC1A1 protein]; Acetylcysteine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine affects the metabolism of SLC1A1 protein] |
CTD |
PMID:18093171 PMID:22575539 |
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NCBI chr19:28,812,535...28,891,360
Ensembl chr19:28,812,449...28,891,360
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G |
Slc1a2 |
solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SLC1A2 protein]; Acetylcysteine inhibits the reaction [Cocaine results in decreased expression of SLC1A2 protein] Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 mRNA]; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 protein] |
CTD |
PMID:19717140 PMID:22895544 PMID:34310962 |
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NCBI chr 2:102,488,584...102,621,129
Ensembl chr 2:102,489,004...102,621,129
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G |
Slc22a17 |
solute carrier family 22 (organic cation transporter), member 17 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of SLC22A17 mRNA] |
CTD |
PMID:31004932 |
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NCBI chr14:55,144,184...55,154,527
Ensembl chr14:55,143,761...55,150,589
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G |
Slc22a19 |
solute carrier family 22 (organic anion transporter), member 19 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of SLC22A24 protein] |
CTD |
PMID:26230185 |
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NCBI chr19:7,650,440...7,688,675
Ensembl chr19:7,650,426...7,688,675
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G |
Slc22a4 |
solute carrier family 22 (organic cation transporter), member 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased activity of SLC22A4 protein] |
CTD |
PMID:25490951 |
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NCBI chr11:53,873,941...53,920,866
Ensembl chr11:53,873,949...53,918,916
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G |
Slc22a5 |
solute carrier family 22 (organic cation transporter), member 5 |
multiple interactions |
ISO |
Acetylcysteine affects the reaction [Methylmercury Compounds results in decreased transport of SLC22A5 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased transport of SLC22A5 protein] |
CTD |
PMID:22900493 |
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NCBI chr11:53,755,368...53,782,609
Ensembl chr11:53,755,368...53,782,486
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G |
Slc22a6 |
solute carrier family 22 (organic anion transporter), member 6 |
multiple interactions |
ISO |
adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; Glutarates inhibits the reaction [SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]]; Ketoglutaric Acids inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]]; SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]; SLC22A6 protein results in increased transport of [Acetylcysteine co-treated with Mercury]; SLC22A6 protein results in increased transport of [Acetylcysteine co-treated with Methylmercury Compounds]; SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine] |
CTD |
PMID:12606766 PMID:15908511 |
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NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
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G |
Slc22a8 |
solute carrier family 22 (organic anion transporter), member 8 |
multiple interactions |
ISO |
SLC22A8 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine] |
CTD |
PMID:12606766 |
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NCBI chr19:8,568,576...8,589,199
Ensembl chr19:8,568,618...8,589,199
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G |
Slc24a2 |
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC24A2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:86,901,361...87,148,780
Ensembl chr 4:86,901,361...87,148,714
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G |
Slc25a20 |
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SLC25A20 protein] Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of SLC25A20 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased activity of SLC25A20 protein] |
CTD |
PMID:23402788 PMID:25849418 |
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NCBI chr 9:108,539,335...108,561,841
Ensembl chr 9:108,539,287...108,561,840
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G |
Slc25a47 |
solute carrier family 25, member 47 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC25A47 mRNA |
CTD |
PMID:22129741 |
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NCBI chr12:108,815,740...108,822,741
Ensembl chr12:108,801,972...108,822,741
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G |
Slc27a2 |
solute carrier family 27 (fatty acid transporter), member 2 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Dietary Fats] results in increased expression of SLC27A2 mRNA |
CTD |
PMID:21051528 |
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NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163
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G |
Slc2a1 |
solute carrier family 2 (facilitated glucose transporter), member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA]; Acetylcysteine inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of SLC2A1 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of SLC2A1 mRNA]; Acetylcysteine inhibits the reaction [icaritin results in decreased expression of SLC2A1 protein] |
CTD |
PMID:30821169 PMID:31251971 PMID:31724279 PMID:38431053 |
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NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
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G |
Slc2a2 |
solute carrier family 2 (facilitated glucose transporter), member 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Pyruvaldehyde affects the localization of SLC2A2 protein] |
CTD |
PMID:22917016 |
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NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
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G |
Slc2a3 |
solute carrier family 2 (facilitated glucose transporter), member 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [epigallocatechin gallate results in increased expression of SLC2A3 mRNA]; Acetylcysteine inhibits the reaction [epigallocatechin gallate results in increased expression of SLC2A3 protein] |
CTD |
PMID:31857147 |
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NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599
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G |
Slc2a4 |
solute carrier family 2 (facilitated glucose transporter), member 4 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein] |
CTD |
PMID:27117918 |
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NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014
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G |
Slc30a1 |
solute carrier family 30 (zinc transporter), member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SLC30A1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 1:191,638,810...191,645,359
Ensembl chr 1:191,638,879...191,645,359
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G |
Slc35d2 |
solute carrier family 35, member D2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of SLC35D2 mRNA] |
CTD |
PMID:33146789 |
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NCBI chr13:64,244,122...64,277,195
Ensembl chr13:64,244,122...64,277,182
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G |
Slc38a2 |
solute carrier family 38, member 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [arsenite results in increased expression of SLC38A2 mRNA] |
CTD |
PMID:22215663 |
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NCBI chr15:96,585,267...96,597,609
Ensembl chr15:96,585,273...96,597,611
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G |
Slc39a14 |
solute carrier family 39 (zinc transporter), member 14 |
increases expression |
ISO |
Acetylcysteine results in increased expression of SLC39A14 mRNA |
CTD |
PMID:16084531 |
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NCBI chr14:70,540,916...70,588,873
Ensembl chr14:70,540,918...70,588,874
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G |
Slc40a1 |
solute carrier family 40 (iron-regulated transporter), member 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SLC40A1 mRNA] |
CTD |
PMID:20090884 |
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NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683
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G |
Slc4a1 |
solute carrier family 4 (anion exchanger), member 1 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite affects the localization of SLC4A1 protein] |
CTD |
PMID:20946910 |
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NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029
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G |
Slc5a5 |
solute carrier family 5 (sodium iodide symporter), member 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SLC5A5 mRNA] |
CTD |
PMID:30352396 |
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NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401
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G |
Slc6a6 |
solute carrier family 6 (neurotransmitter transporter, taurine), member 6 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC6A6 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047
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G |
Slc7a11 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cocaine results in decreased expression of SLC7A11 protein] Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SLC7A11 mRNA] |
CTD |
PMID:18723479 PMID:19717140 |
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NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
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G |
Slc7a14 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC7A14 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:31,257,003...31,364,712
Ensembl chr 3:31,257,007...31,364,527
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G |
Smad1 |
SMAD family member 1 |
decreases phosphorylation |
ISO |
Acetylcysteine results in decreased phosphorylation of SMAD1 protein |
CTD |
PMID:32947957 |
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NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147
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G |
Smad2 |
SMAD family member 2 |
multiple interactions decreases phosphorylation |
ISO EXP |
Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of SMAD2 mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of SMAD2 mRNA] Acetylcysteine results in decreased phosphorylation of SMAD2 protein Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of SMAD2 protein] |
CTD |
PMID:29408318 PMID:30317545 PMID:32947957 PMID:38488660 |
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NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
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G |
Smad3 |
SMAD family member 3 |
multiple interactions decreases phosphorylation |
ISO EXP |
[Acetylcysteine co-treated with Cadmium Chloride co-treated with sodium arsenite] results in decreased expression of SMAD3 mRNA; [Acetylcysteine co-treated with Cadmium] results in decreased expression of SMAD3 mRNA; [Acetylcysteine co-treated with Water Pollutants, Chemical] results in decreased expression of SMAD3 mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of SMAD3 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] Acetylcysteine results in decreased phosphorylation of SMAD3 protein Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of SMAD3 protein] |
CTD |
PMID:21131394 PMID:29408318 PMID:30317545 PMID:34687772 PMID:38488660 PMID:39197814 More...
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NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
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G |
Smc1a |
structural maintenance of chromosomes 1A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of SMC1A protein]]; Acetylcysteine inhibits the reaction [resveratrol results in increased phosphorylation of SMC1A protein] |
CTD |
PMID:15489221 PMID:24933654 |
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NCBI chr X:150,799,386...150,844,969
Ensembl chr X:150,799,424...150,845,690
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G |
Snai1 |
snail family zinc finger 1 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SNAI1 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of SNAI1 protein]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [propiconazole results in increased expression of SNAI1 protein] Acetylcysteine results in decreased expression of SNAI1 protein |
CTD |
PMID:17596522 PMID:21635667 PMID:28284859 PMID:32687844 PMID:34170130 PMID:34687772 More...
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NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734
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G |
Snai2 |
snail family zinc finger 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of SNAI2 protein] |
CTD |
PMID:32687844 |
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NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249
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G |
Snca |
synuclein, alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in increased expression of SNCA protein] Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SNCA mRNA]; Acetylcysteine inhibits the reaction [Lead results in increased expression of SNCA mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased expression of SNCA protein] |
CTD |
PMID:15114628 PMID:27613482 PMID:34816377 |
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NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
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G |
Sntg1 |
syntrophin, gamma 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SNTG1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:8,429,963...9,371,882
Ensembl chr 1:8,431,699...9,370,103
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G |
Sod1 |
superoxide dismutase 1, soluble |
multiple interactions increases activity decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Nitroprusside] results in decreased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [Antimony results in decreased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [bisphenol S results in decreased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of SOD1]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of SOD1 protein]; Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD1 mRNA] Acetylcysteine results in increased activity of SOD1 protein Acetylcysteine results in decreased expression of SOD1 mRNA [Acetylcysteine co-treated with Thapsigargin] results in decreased expression of SOD1 mRNA; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [perfluorooctanoic acid results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in decreased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in decreased expression of SOD1 protein] Acetylcysteine inhibits the reaction [Cadmium results in decreased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [Lead results in decreased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of SOD1 protein] |
CTD |
PMID:16101137 PMID:17309078 PMID:19264484 PMID:19409983 PMID:20674559 PMID:21888768 PMID:22155089 PMID:22714038 PMID:24299490 PMID:28013216 PMID:28535741 PMID:29111403 PMID:32023790 PMID:32092105 PMID:32578922 PMID:34816377 PMID:35112789 PMID:35810264 PMID:36813253 PMID:37084995 PMID:37692514 PMID:37944787 PMID:38097005 PMID:39362619 More...
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NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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G |
Sod2 |
superoxide dismutase 2, mitochondrial |
multiple interactions increases expression |
EXP ISO |
[Acetylcysteine results in increased expression of SOD2 protein] which results in decreased abundance of Reactive Oxygen Species; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Cyclosporine results in decreased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Acetylcysteine promotes the reaction [Oxygen results in increased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [Oxygen results in increased expression of SOD2 protein] Acetylcysteine results in increased expression of SOD2 mRNA; Acetylcysteine results in increased expression of SOD2 protein [Acetylcysteine co-treated with IL1A protein] results in increased expression of SOD2 protein; [Acetylcysteine co-treated with TNF protein] results in increased expression of SOD2 protein; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of SOD2 mRNA; Acetylcysteine affects the reaction [SOD2 protein affects the activity of CASP9 protein]; Acetylcysteine affects the reaction [SOD2 protein results in decreased susceptibility to Doxorubicin]; Acetylcysteine affects the reaction [SOD2 protein results in decreased susceptibility to Paclitaxel]; Acetylcysteine inhibits the reaction [[[15-deoxyprostaglandin J2 results in increased activity of PPARG protein] which results in decreased expression of SOD2 protein] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Nitroprusside] results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Glucose deficiency affects the folding of SOD2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [linsidomine results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Peroxynitrous Acid results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of and results in increased activity of SOD2 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the activity of AR protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AKR1C3 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AMACR mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR1 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR2 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of FKBP5 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD11B2 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD17B8 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of KLK3 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of PGR mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of RXRA mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of TMPRSS2 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2]; Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [TNF protein results in increased expression of SOD2 mRNA]; TNF protein promotes the reaction [Acetylcysteine results in increased expression of SOD2 mRNA] Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased acetylation of SOD2 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in decreased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased acetylation of SOD2 protein]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of SOD2 mRNA] |
CTD |
PMID:7476933 PMID:8760145 PMID:9535218 PMID:9741582 PMID:11264281 PMID:12031898 PMID:15904944 PMID:16101137 PMID:17010595 PMID:17309078 PMID:18594523 PMID:18829485 PMID:20674559 PMID:21131394 PMID:21775390 PMID:22429591 PMID:22714038 PMID:22718889 PMID:23114885 PMID:23159718 PMID:23765110 PMID:23964924 PMID:28499986 PMID:29111403 PMID:30104959 PMID:30641872 PMID:32023790 PMID:32092105 PMID:35403558 PMID:35430258 More...
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NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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G |
Sod3 |
superoxide dismutase 3, extracellular |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SOD3 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of SOD3 protein] |
CTD |
PMID:21804221 PMID:34358621 |
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NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
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G |
Sord |
sorbitol dehydrogenase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Diclofenac results in increased secretion of SORD protein] |
CTD |
PMID:12763371 |
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NCBI chr 2:122,065,320...122,095,818
Ensembl chr 2:122,065,230...122,095,821
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G |
Sox17 |
SRY (sex determining region Y)-box 17 |
multiple interactions |
ISO |
N-acetyl-cysteine inhibits the reaction [angiotensin II decreases expression of SOX17 protein in retinal endothelial cells] |
RGD |
PMID:32078435 |
RGD:329853329 |
NCBI chr 1:4,561,154...4,567,624
Ensembl chr 1:4,561,154...4,567,577
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G |
Sp1 |
trans-acting transcription factor 1 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Camptothecin results in increased expression of SP1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SP1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of SP1 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of SP1 protein] Acetylcysteine results in decreased expression of SP1 protein |
CTD |
PMID:16928829 PMID:18556457 PMID:30851366 PMID:33360347 |
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NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
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G |
Sphk1 |
sphingosine kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Glucose results in increased expression of and results in increased activity of SPHK1 protein] |
CTD |
PMID:21998146 |
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NCBI chr11:116,421,662...116,427,502
Ensembl chr11:116,421,751...116,427,501
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G |
Spi1 |
Spi-1 proto-oncogene |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of SPI1 mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of SPI1 mRNA]] |
CTD |
PMID:29945211 |
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NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101
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G |
Spock2 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SPOCK2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr10:59,942,079...59,971,020
Ensembl chr10:59,942,041...59,971,020
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Allylamine results in increased expression of SPP1 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein] |
CTD |
PMID:15910882 PMID:19356721 |
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NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine affects the reaction [sodium arsenite affects the expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Acrolein results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [alpha-pyrrolidinononanophenone results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [aumolertinib results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [brazilin results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein]; Acetylcysteine inhibits the reaction [ovatodiolide results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Patulin results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [tri-o-cresyl phosphate results in increased expression of SQSTM1 protein] Acetylcysteine inhibits the reaction [decamethrin results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone results in increased expression of SQSTM1 protein]; Acetylcysteine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in decreased expression of SQSTM1 protein] Acetylcysteine results in increased expression of SQSTM1 protein |
CTD |
PMID:22927544 PMID:25301941 PMID:26588882 PMID:27106530 PMID:28063998 PMID:28578026 PMID:29222055 PMID:29604266 PMID:29923297 PMID:30205151 PMID:31563593 PMID:32512069 PMID:32525552 PMID:33462182 PMID:33617914 PMID:34219533 PMID:34547296 PMID:34861471 PMID:35550146 PMID:36739042 PMID:37678662 PMID:38000454 PMID:38604309 More...
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NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
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G |
Src |
Rous sarcoma oncogene |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of SRC protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of SRC protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of SRC protein] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of SRC protein in the stomach) |
CTD RGD |
PMID:21777978 PMID:29894800 PMID:31433961 PMID:29408335 |
RGD:127284846 |
NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
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G |
Srms |
src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SRMS mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:180,847,356...180,854,964
Ensembl chr 2:180,847,355...180,854,978
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G |
Srxn1 |
sulfiredoxin 1 homolog (S. cerevisiae) |
multiple interactions |
EXP |
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [Cadmium Chloride results in increased expression of SRXN1 mRNA]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [Copper Sulfate results in increased expression of SRXN1 mRNA]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [Methyl Methanesulfonate results in increased expression of SRXN1 mRNA]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [sodium arsenite results in increased expression of SRXN1 mRNA] |
CTD |
PMID:22003191 |
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NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of STAR protein] Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of STAR mRNA] Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of STAR protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of STAR protein] |
CTD |
PMID:25617244 PMID:26769589 PMID:29567110 PMID:30648648 PMID:36709824 |
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NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
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G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased phosphorylation of STAT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased phosphorylation of STAT1 protein]; Acetylcysteine inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein] Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein] Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:12847270 PMID:16896058 PMID:17607690 PMID:19061877 PMID:20525893 PMID:36154299 More...
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NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions decreases phosphorylation treatment |
ISO EXP |
Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of and results in increased expression of STAT3 protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of and results in increased activity of STAT3 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein] Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of STAT3 mRNA]; Acetylcysteine inhibits the reaction [NSC 680410 results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of STAT3 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein] Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]] Acetylcysteine results in decreased phosphorylation of STAT3 protein N-acetyl-L-cysteine co-treated with Il-6 inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of STAT3 protein in the stomach) |
CTD RGD |
PMID:16481037 PMID:16896058 PMID:17666914 PMID:19409983 PMID:21741372 PMID:21912612 PMID:23948867 PMID:24582688 PMID:24820114 PMID:27856279 PMID:28284859 PMID:28739487 PMID:29329563 PMID:29894800 PMID:30871965 PMID:31433961 PMID:33030807 PMID:34425375 PMID:34627931 PMID:29408335 More...
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RGD:127284846 |
NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
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G |
Sumo1 |
small ubiquitin-like modifier 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of SUMO1 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr 1:59,678,593...59,709,993
Ensembl chr 1:59,625,717...59,709,993
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G |
Syn1 |
synapsin I |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of SYN1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of SYN1 protein] |
CTD |
PMID:27624276 PMID:28153600 |
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NCBI chr X:20,726,750...20,787,157
Ensembl chr X:20,726,750...20,787,243
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G |
Syp |
synaptophysin |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SYP protein] |
CTD |
PMID:28499986 |
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NCBI chr X:7,504,819...7,519,495
Ensembl chr X:7,504,710...7,519,495
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G |
Syt7 |
synaptotagmin VII |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Dexamethasone] results in decreased expression of SYT7 mRNA |
CTD |
PMID:21888768 |
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NCBI chr19:10,366,142...10,430,545
Ensembl chr19:10,366,454...10,430,544
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G |
Tab2 |
TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
decreases binding |
ISO |
N-acetyl-cysteine inhibits binding of Traf6 protein to Tab2 in rat neonatal cardiomyocytes |
RGD |
PMID:27249171 |
RGD:155646134 |
NCBI chr10:7,781,412...7,832,039
Ensembl chr10:7,781,417...7,831,994
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G |
Taldo1 |
transaldolase 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased abundance of Glutathione]; Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased abundance of NADP]; Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased abundance of Nitric Oxide]; Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased phosphorylation of CTNNB1 protein] |
CTD |
PMID:19436114 |
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NCBI chr 7:140,972,073...140,982,889
Ensembl chr 7:140,972,112...140,982,881
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G |
Tank |
TRAF family member-associated Nf-kappa B activator |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of TANK mRNA |
CTD |
PMID:16084531 |
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NCBI chr 2:61,408,901...61,484,515
Ensembl chr 2:61,408,929...61,484,515
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G |
Tardbp |
TAR DNA binding protein |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenite promotes the reaction [TARDBP protein binds to PPP1R15A protein]] |
CTD |
PMID:29109149 |
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NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476
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G |
Tas2r108 |
taste receptor, type 2, member 108 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TAS2R108 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:40,470,526...40,471,419
Ensembl chr 6:40,470,463...40,471,475
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G |
Tert |
telomerase reverse transcriptase |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Camptothecin results in increased expression of TERT protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of TERT protein] Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased activity of TERT protein]; Acetylcysteine inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein] Acetylcysteine results in increased expression of TERT protein |
CTD |
PMID:18336854 PMID:19409983 PMID:30851366 |
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NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
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G |
Tet1 |
tet methylcytosine dioxygenase 1 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [TET1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TET1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TET1 mRNA] Acetylcysteine results in increased expression of TET1 mRNA [[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with Acetylcysteine] results in decreased expression of TET1 mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TET1 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of TET1 mRNA] |
CTD |
PMID:28153600 PMID:31551408 PMID:33188856 |
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NCBI chr10:62,640,349...62,723,242
Ensembl chr10:62,640,349...62,744,775
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G |
Tet2 |
tet methylcytosine dioxygenase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of TET2 protein] |
CTD |
PMID:31900833 |
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NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of TFAM mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of TFAM mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of TFAM mRNA]; Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of TFAM mRNA] Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of TFAM mRNA]; Acetylcysteine inhibits the reaction [dimethoxyethyl phthalate results in decreased expression of TFAM protein] |
CTD |
PMID:21775390 PMID:26980303 PMID:32142722 PMID:34214916 PMID:35403558 PMID:36493885 More...
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NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
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G |
Tfe3 |
transcription factor E3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in decreased expression of TFE3 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased phosphorylation of and affects the localization of TFE3 protein] |
CTD |
PMID:29945972 PMID:32439580 |
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NCBI chr X:7,628,769...7,641,441
Ensembl chr X:7,628,799...7,641,441
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G |
Tfeb |
transcription factor EB |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal affects the localization of TFEB protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of TFEB protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of TFEB mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased phosphorylation of TFEB protein] |
CTD |
PMID:29307831 PMID:29945972 PMID:33462182 PMID:35550146 |
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NCBI chr17:48,047,962...48,103,341
Ensembl chr17:48,047,955...48,103,344
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G |
Tfrc |
transferrin receptor |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Zinc deficiency results in increased expression of TFRC protein] |
CTD |
PMID:18073202 |
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NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
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G |
Tgfa |
transforming growth factor alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of TGFA mRNA] |
CTD |
PMID:15945272 |
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NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions decreases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of TGFB1 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of TGFB1 mRNA] Acetylcysteine inhibits the reaction [4-cresol sulfate results in increased expression of and results in increased secretion of TGFB1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of TGFB1 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of PPM1A protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of HGF protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased secretion of IL6 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of TGFB1 protein] Acetylcysteine results in decreased expression of TGFB1 mRNA; Acetylcysteine results in decreased expression of TGFB1 protein modified form |
CTD |
PMID:16757516 PMID:21131394 PMID:21765237 PMID:23159718 PMID:23325087 PMID:25406100 PMID:26138014 PMID:30317545 PMID:30543783 PMID:32947957 PMID:36493885 PMID:38488660 PMID:39197814 More...
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NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
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G |
Tgfb1i1 |
transforming growth factor beta 1 induced transcript 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Ethylmercury Compounds results in increased expression of TGFB1I1 mRNA] |
CTD |
PMID:27511942 |
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NCBI chr 7:127,845,963...127,852,884
Ensembl chr 7:127,845,984...127,854,871
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G |
Tgfb3 |
transforming growth factor, beta 3 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Cadmium] results in decreased expression of TGFB3 mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of and results in increased secretion of TGFB3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of TGFB3 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of and results in increased secretion of TGFB3 protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of and results in increased secretion of TGFB3 protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of TGFB3 mRNA] |
CTD |
PMID:29408318 |
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NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815
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G |
Tgfbr1 |
transforming growth factor, beta receptor I |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of TGFBR1 mRNA; Acetylcysteine results in decreased expression of TGFBR1 protein Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR1 protein] [Acetylcysteine co-treated with Cadmium] results in decreased expression of TGFBR1 mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of TGFBR1 mRNA]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of TGFBR1 mRNA] |
CTD |
PMID:17602960 PMID:29408318 |
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NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
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G |
Tgfbr2 |
transforming growth factor, beta receptor II |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of TGFBR2 mRNA; Acetylcysteine results in decreased expression of TGFBR2 protein Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR2 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR2 protein] |
CTD |
PMID:17602960 |
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NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428
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G |
Tgm1 |
transglutaminase 1, K polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter analog results in decreased activity of TGM1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in decreased activity of TGM1 protein] |
CTD |
PMID:15541757 |
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NCBI chr14:55,937,466...55,951,378
Ensembl chr14:55,937,466...55,951,383
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G |
Tgm2 |
transglutaminase 2, C polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter analog results in decreased activity of TGM2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in decreased activity of TGM2 protein] |
CTD |
PMID:15541757 |
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NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356
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G |
Th |
tyrosine hydroxylase |
multiple interactions decreases expression |
ISO |
[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein] Acetylcysteine results in decreased expression of TH protein |
CTD |
PMID:22714038 PMID:25891525 |
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NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
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G |
Thbs1 |
thrombospondin 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of TSP1 mRNA] |
CTD |
PMID:20524210 |
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NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
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G |
Thpo |
thrombopoietin |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [THPO protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of GP1BA protein]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of ITGA2B protein]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of ITGB3 protein] |
CTD |
PMID:20523355 |
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NCBI chr16:20,543,204...20,553,261
Ensembl chr16:20,543,204...20,553,261
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G |
Timp2 |
tissue inhibitor of metalloproteinase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP2 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP2 mRNA] |
CTD |
PMID:33188856 |
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NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566
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G |
Timp3 |
tissue inhibitor of metalloproteinase 3 |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP3 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP3 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of TIMP3 mRNA] Acetylcysteine results in increased expression of TIMP3 mRNA |
CTD |
PMID:33188856 |
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NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370
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G |
Tjp1 |
tight junction protein 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of TJP1 protein]; Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of TJP1 protein] Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of TJP1 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in decreased expression of TJP1 protein] Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of TJP1 protein] |
CTD |
PMID:26079211 PMID:27783111 PMID:29235125 PMID:32687961 PMID:33485121 PMID:34906888 PMID:37598416 More...
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NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
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G |
Tjp2 |
tight junction protein 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Glucose results in decreased expression of TJP2 protein] |
CTD |
PMID:27783111 |
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NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394
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G |
Tlr2 |
toll-like receptor 2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of TLR2 mRNA |
CTD |
PMID:22385246 |
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NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions decreases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]; Acetylcysteine inhibits the reaction [benzanthrone results in increased expression of TLR4 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of TLR4 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 mRNA] Acetylcysteine results in decreased expression of TLR4 mRNA Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of TLR4 protein] |
CTD |
PMID:19627980 PMID:22385246 PMID:28495615 PMID:36055550 PMID:37369159 PMID:39260547 More...
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NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
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G |
Tmem140 |
transmembrane protein 140 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TMEM140 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 6:34,840,081...34,851,881
Ensembl chr 6:34,840,081...34,851,881
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G |
Tnc |
tenascin C |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of TNC mRNA |
CTD |
PMID:32947957 |
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NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252
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G |
Tnf |
tumor necrosis factor |
decreases expression multiple interactions affects expression |
ISO EXP |
Acetylcysteine results in decreased expression of TNF mRNA; Acetylcysteine results in decreased expression of TNF protein Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of TNF protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [[Buthionine Sulfoximine co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Nitric Oxide deficiency results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [Palmitates results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [TNF protein affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein results in decreased phosphorylation of PTK2B protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine promotes the reaction [caryophyllene inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; Acetylcysteine promotes the reaction [Doxorubicin results in increased expression of TNF mRNA] Acetylcysteine affects the expression of TNF protein [Acetylcysteine co-treated with TNF protein] results in decreased activity of RELA protein; [Acetylcysteine co-treated with TNF protein] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [2,4-decadienal results in increased expression of and results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [butylphen results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of TNF mRNA]]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of TNF mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Mimosine results in decreased activity of TNF protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [piperlongumine analog inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [TNF protein results in decreased abundance of Glutathione]; Acetylcysteine inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; Acetylcysteine inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TNF protein results in increased abundance of Superoxides]; Acetylcysteine inhibits the reaction [TNF protein results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased cleavage of and results in increased activity of CASP1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [TNF results in decreased expression of NOS3 protein]; Acetylcysteine inhibits the reaction [TNF results in increased abundance of Malondialdehyde]; Acetylcysteine inhibits the reaction [TNF results in increased abundance of Nitric Oxide]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of TNF protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of TNF protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; Acetylcysteine promotes the reaction [TNF protein results in increased expression of SOD2 mRNA]; TNF protein promotes the reaction [Acetylcysteine results in increased expression of SOD2 mRNA] [Acetylcysteine co-treated with raubasine] results in increased secretion of TNF protein; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of TNF mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of TNF protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [azoxystrobin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Fungal Polysaccharides results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [iprodione inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Mimosine results in decreased activity of TNF protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [PRKAA2 protein affects the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]] |
CTD |
PMID:7476933 PMID:7532384 PMID:8760145 PMID:9535218 PMID:9721806 PMID:10495789 PMID:10878378 PMID:10921504 PMID:11124598 PMID:11167962 PMID:11264281 PMID:11970852 PMID:12388057 PMID:12615669 PMID:15050407 PMID:15158148 PMID:15161907 PMID:15451797 PMID:15550384 PMID:15601679 PMID:15650392 PMID:15795323 PMID:15945272 PMID:16014734 PMID:16214328 PMID:16632126 PMID:17026986 PMID:17216608 PMID:17471172 PMID:17666914 PMID:18257742 PMID:18755394 PMID:19176594 PMID:19477266 PMID:19608869 PMID:21237301 PMID:21424515 PMID:21912612 PMID:22385246 PMID:22472292 PMID:23159886 PMID:23268108 PMID:23774252 PMID:23900960 PMID:23940760 PMID:23948867 PMID:24224404 PMID:24316229 PMID:24447977 PMID:24530511 PMID:24570342 PMID:24793810 PMID:24961358 PMID:25406100 PMID:26332274 PMID:26683377 PMID:26801986 PMID:27313093 PMID:28087840 PMID:28535741 PMID:28555929 PMID:28836394 PMID:29111459 PMID:29426002 PMID:29479036 PMID:29753051 PMID:29753072 PMID:30259999 PMID:30529211 PMID:30639957 PMID:31173782 PMID:31518571 PMID:32142722 PMID:32402895 PMID:32620109 PMID:32687961 PMID:33226166 PMID:33720480 PMID:34310962 PMID:35285579 PMID:35349355 PMID:35833596 PMID:36055550 PMID:36493885 PMID:36762617 PMID:36880428 PMID:37458150 PMID:37598416 PMID:38064316 PMID:38513841 PMID:39260547 More...
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NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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G |
Tnfaip3 |
tumor necrosis factor, alpha-induced protein 3 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TNFAIP3 mRNA] |
CTD |
PMID:16137721 |
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NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
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G |
Tnfaip6 |
tumor necrosis factor alpha induced protein 6 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA] |
CTD |
PMID:21220312 |
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NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
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G |
Tnfrsf10b |
tumor necrosis factor receptor superfamily, member 10b |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased expression of TNFRSF10A protein]; Acetylcysteine inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A mRNA]; Acetylcysteine inhibits the reaction [pendulone results in increased expression of TNFRSF10A protein] Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TNFRSF10B mRNA]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TNFRSF10B protein] |
CTD |
PMID:21741372 PMID:24930757 PMID:27484784 PMID:35288263 |
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NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
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G |
Tnfrsf13c |
tumor necrosis factor receptor superfamily, member 13c |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TNFRSF13C mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:82,105,943...82,108,581
Ensembl chr15:82,105,944...82,108,570
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G |
Tnfrsf1a |
tumor necrosis factor receptor superfamily, member 1a |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of TNFRSF1A protein]; Acetylcysteine inhibits the reaction [Mimosine results in increased cleavage of TNFRSF1A protein] |
CTD |
PMID:15550384 PMID:21741372 |
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NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
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G |
Tnfrsf1b |
tumor necrosis factor receptor superfamily, member 1b |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TNFRSF1B mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
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G |
Tnfsf10 |
tumor necrosis factor (ligand) superfamily, member 10 |
decreases expression multiple interactions decreases response to substance |
ISO |
Acetylcysteine results in decreased expression of TNFSF10 mRNA Acetylcysteine inhibits the reaction [[CSC-3436 co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with tanshinone] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in decreased expression of CFLAR protein modified form]]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased abundance of Reactive Nitrogen Species]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased chemical synthesis of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of VDAC1 protein] Acetylcysteine results in decreased susceptibility to TNFSF10 protein |
CTD |
PMID:16084531 PMID:20971099 PMID:23711929 PMID:25034532 PMID:25619640 PMID:26203587 PMID:34599545 More...
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NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
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G |
Tnfsf11 |
tumor necrosis factor (ligand) superfamily, member 11 |
multiple interactions |
EXP |
[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of ATP6V0D2 mRNA; [Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNFSF11]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:30742845 PMID:38971422 |
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NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
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G |
Tnfsf4 |
tumor necrosis factor (ligand) superfamily, member 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TNFSF4 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of TNFSF4 mRNA] |
CTD |
PMID:20974985 |
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NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981
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G |
Tnni3 |
troponin I, cardiac 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of TNNI3 protein] |
CTD |
PMID:31928237 |
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NCBI chr 7:4,521,304...4,526,228
Ensembl chr 7:4,521,304...4,527,228
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G |
Tnpo1 |
transportin 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [manumycin results in decreased expression of TNPO1] |
CTD |
PMID:19409983 |
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NCBI chr13:98,975,527...99,062,851
Ensembl chr13:98,975,527...99,062,892
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G |
Tomm20 |
translocase of outer mitochondrial membrane 20 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in decreased expression of TOMM20 protein] |
CTD |
PMID:36739042 |
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NCBI chr 8:127,657,414...127,672,671
Ensembl chr 8:127,657,417...127,672,594
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G |
Tor3a |
torsin family 3, member A |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TOR3A mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TOR3A mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 1:156,481,187...156,501,909
Ensembl chr 1:156,481,187...156,501,926
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G |
Tpm1 |
tropomyosin 1, alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Allylamine results in increased expression of TPM1 mRNA] |
CTD |
PMID:15910882 |
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NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688
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G |
Tpo |
thyroid peroxidase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of TPO mRNA] |
CTD |
PMID:30352396 |
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NCBI chr12:30,104,658...30,182,983
Ensembl chr12:30,104,658...30,182,623
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G |
Traf2 |
TNF receptor-associated factor 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]] |
CTD |
PMID:24394546 |
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NCBI chr 2:25,407,994...25,436,952
Ensembl chr 2:25,407,994...25,436,952
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G |
Traf6 |
TNF receptor-associated factor 6 |
decreases binding multiple interactions |
ISO |
N-acetyl-cysteine inhibits binding of Traf6 protein to Tab2 in rat neonatal cardiomyocytes N-acetyl-L-cysteine inhibits the reaction [angiotensin II increases expression of Traf6 protein in rat neonatal cardiomyocytes] |
RGD |
PMID:27249171 PMID:27249171 |
RGD:155646134, RGD:155646134 |
NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014
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G |
Trib1 |
tribbles pseudokinase 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TRIB1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:59,520,503...59,528,948
Ensembl chr15:59,520,199...59,528,948
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G |
Trib3 |
tribbles pseudokinase 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of TRIB3 mRNA] Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of TRIB3 mRNA] |
CTD |
PMID:18723479 PMID:24291486 |
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NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
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G |
Trim28 |
tripartite motif-containing 28 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [resveratrol results in increased phosphorylation of TRIM28 protein] |
CTD |
PMID:24933654 |
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NCBI chr 7:12,758,079...12,764,959
Ensembl chr 7:12,733,041...12,764,962
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G |
Troap |
trophinin associated protein |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TROAP mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:98,972,854...98,981,290
Ensembl chr15:98,972,456...98,981,290
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G |
Trp53 |
transformation related protein 53 |
multiple interactions decreases activity decreases expression increases phosphorylation increases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TRP53 protein]; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of TRP53 protein modified form]; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of TRP53 protein]; Acetylcysteine inhibits the reaction [[Excitatory Amino Acid Agents results in increased abundance of Reactive Oxygen Species] which results in increased activity of TRP53 protein]; Acetylcysteine inhibits the reaction [[Excitatory Amino Acid Agents results in increased abundance of Reactive Oxygen Species] which results in increased expression of TRP53 mRNA]; Acetylcysteine inhibits the reaction [[Excitatory Amino Acid Agents results in increased abundance of Reactive Oxygen Species] which results in increased expression of TRP53 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in increased phosphorylation of TRP53 protein]; Acetylcysteine inhibits the reaction [dihydrolipoic acid results in increased expression of TRP53 mRNA]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of TRP53 mRNA]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of TRP53 protein modified form]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of TRP53 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of TRP53 protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of TRP53 protein] [Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; [chloroquine diphosphate co-treated with Acetylcysteine] results in decreased localization of TP53 protein; [Hydroxychloroquine co-treated with Acetylcysteine] results in decreased localization of TP53 protein; Acetylcysteine affects the reaction [4-biphenylamine affects the expression of TP53 protein]; Acetylcysteine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein modified form]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with Arsenic Trioxide] results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [ATM protein promotes the reaction [Doxorubicin results in increased activity of TP53 protein]]; Acetylcysteine inhibits the reaction [Camptothecin results in increased expression of TP53 protein modified form]; Acetylcysteine inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of TP53]; Acetylcysteine inhibits the reaction [Cisplatin results in increased glutathionylation of TP53 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of and results in increased activity of TP53 protein]; Acetylcysteine inhibits the reaction [cyadox results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased expression of and results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [hesperetin results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [icaritin results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Oxaliplatin results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of TP53 protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased expression of TP53]; Acetylcysteine inhibits the reaction [Phytochemicals results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TP53 protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [usnic acid results in increased expression of TP53 protein]; Acetylcysteine promotes the reaction [Chlorine results in increased expression of TP53 protein modified form] Acetylcysteine results in decreased activity of TP53 protein Acetylcysteine results in decreased expression of TP53 protein Acetylcysteine results in increased phosphorylation of TP53 protein Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]]; Acetylcysteine inhibits the reaction [Aflatoxin B1 results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Quercetin analog results in decreased phosphorylation of TP53 protein] Acetylcysteine results in increased expression of TP53 protein |
CTD |
PMID:9535218 PMID:10951577 PMID:11864783 PMID:14871840 PMID:15059885 PMID:15489221 PMID:15496615 PMID:15904916 PMID:17555331 PMID:18034189 PMID:18563748 PMID:18951928 PMID:18996350 PMID:19202565 PMID:19728331 PMID:20530418 PMID:20955365 PMID:21462292 PMID:21549813 PMID:21565247 PMID:22183962 PMID:22260869 PMID:22927544 PMID:23183129 PMID:23274516 PMID:23711929 PMID:23907460 PMID:24792323 PMID:24967384 PMID:25305377 PMID:25845326 PMID:25939952 PMID:26451628 PMID:26884717 PMID:26942697 PMID:27634759 PMID:27658547 PMID:28181396 PMID:29944906 PMID:29945211 PMID:29962303 PMID:30265530 PMID:30408460 PMID:30555576 PMID:31173782 PMID:31433961 PMID:31715134 PMID:32017938 PMID:32402895 PMID:32540572 PMID:32905825 PMID:32924446 PMID:33031904 PMID:33961949 PMID:35065218 PMID:35123993 PMID:36493885 PMID:37487865 PMID:38311193 PMID:38431053 More...
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NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; Acetylcysteine inhibits the reaction [[Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium] |
CTD |
PMID:27738742 |
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NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086
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G |
Trpc7 |
transient receptor potential cation channel, subfamily C, member 7 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TRPC7 mRNA |
CTD |
PMID:22129741 |
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NCBI chr13:56,920,911...57,043,778
Ensembl chr13:56,920,926...57,043,806
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G |
Tsc2 |
TSC complex subunit 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of TSC2 protein] |
CTD |
PMID:21195169 |
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NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
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G |
Tshb |
thyroid stimulating hormone, beta subunit |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [TSHB protein results in increased abundance of Hydrogen Peroxide] |
CTD |
PMID:11108245 |
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NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
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G |
Tslp |
thymic stromal lymphopoietin |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TSLP mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of TSLP mRNA] |
CTD |
PMID:18049884 PMID:29753051 |
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NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850
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G |
Tspan6 |
tetraspanin 6 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of TSPAN6 mRNA |
CTD |
PMID:16084531 |
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NCBI chr X:132,791,817...132,801,957
Ensembl chr X:132,791,817...132,799,178
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G |
Ttc7b |
tetratricopeptide repeat domain 7B |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TTC7B mRNA |
CTD |
PMID:22129741 |
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NCBI chr12:100,267,029...100,487,134
Ensembl chr12:100,267,029...100,487,085
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G |
Ttc9b |
tetratricopeptide repeat domain 9B |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TTC9B mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:27,353,349...27,355,632
Ensembl chr 7:27,353,340...27,356,771
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G |
Tubb3 |
tubulin, beta 3 class III |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of TUBB3 mRNA] |
CTD |
PMID:28153600 |
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NCBI chr 8:124,138,292...124,148,754
Ensembl chr 8:124,138,163...124,148,754
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G |
Txn1 |
thioredoxin 1 |
multiple interactions decreases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of TXN protein]; Acetylcysteine inhibits the reaction [Rotenone inhibits the reaction [TXN protein binds to and results in decreased activity of MAP3K5 protein]] Acetylcysteine inhibits the reaction [Acrolein results in increased oxidation of TXN protein]; Acetylcysteine inhibits the reaction [indole-3-carbinol results in decreased expression of TXN protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of TXN protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in increased oxidation of TXN1 protein] Acetylcysteine results in decreased expression of TXN protein |
CTD |
PMID:16449798 PMID:17959236 PMID:18023956 PMID:18922898 PMID:24157283 PMID:33118390 More...
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NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
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G |
Txn2 |
thioredoxin 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of TXN2 mRNA] |
CTD |
PMID:36315628 |
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NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206
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G |
Txndc8 |
thioredoxin domain containing 8 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TXNDC8 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:57,984,029...58,009,126
Ensembl chr 4:57,984,027...58,009,124
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G |
Txnip |
thioredoxin interacting protein |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TXNIP mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TXNIP protein] |
CTD |
PMID:37300869 |
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NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
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G |
Txnl1 |
thioredoxin-like 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of TXNL1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr18:63,795,872...63,825,535
Ensembl chr18:63,794,165...63,841,872
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G |
Txnrd1 |
thioredoxin reductase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acrolein results in increased expression of TXNRD1 mRNA] |
CTD |
PMID:15652504 |
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NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
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G |
Tymp |
thymidine phosphorylase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein] |
CTD |
PMID:11103787 |
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NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242
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G |
Tyr |
tyrosinase |
multiple interactions |
EXP |
[Acetylcysteine co-treated with 6-formylindolo(3,2-b)carbazole] results in increased activity of TYR protein; [Acetylcysteine co-treated with Benzo(a)pyrene] results in increased activity of TYR protein |
CTD |
PMID:34856342 |
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NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
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G |
Uba7 |
ubiquitin-like modifier activating enzyme 7 |
increases expression multiple interactions |
ISO EXP |
Acetylcysteine results in increased expression of UBA7 protein Curcumin affects the reaction [Acetylcysteine results in increased expression of UBA7 protein]; epigallocatechin gallate affects the reaction [Acetylcysteine results in increased expression of UBA7 protein]; resveratrol affects the reaction [Acetylcysteine results in increased expression of UBA7 protein] Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of UBA7 mRNA] |
CTD |
PMID:25649257 PMID:34425375 |
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NCBI chr 9:107,852,766...107,861,255
Ensembl chr 9:107,852,704...107,861,259
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G |
Ucp2 |
uncoupling protein 2 (mitochondrial, proton carrier) |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of UCP2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of UCP2 protein]; Acetylcysteine inhibits the reaction [pirinixic acid results in increased expression of UCP2 protein] Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of UCP2 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of UCP2 protein] |
CTD |
PMID:18183618 PMID:29061315 PMID:30104959 PMID:36493885 |
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NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
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G |
Ufm1 |
ubiquitin-fold modifier 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of UFM1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 3:53,760,797...53,771,228
Ensembl chr 3:53,760,797...53,771,251
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G |
Ugdh |
UDP-glucose dehydrogenase |
increases expression |
ISO |
Acetylcysteine results in increased expression of UGDH mRNA |
CTD |
PMID:16084531 |
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NCBI chr 5:65,570,550...65,593,185
Ensembl chr 5:65,570,564...65,593,292
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G |
Ugt1a6b |
UDP glucuronosyltransferase 1 family, polypeptide A6B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA]; Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of UGT1A6 promoter] |
CTD |
PMID:15336321 PMID:22129741 |
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NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
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G |
Uhrf1 |
ubiquitin-like, containing PHD and RING finger domains, 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of UHRF1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr17:56,610,405...56,630,486
Ensembl chr17:56,610,321...56,630,486
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G |
Ulk1 |
unc-51 like kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Artesunate results in increased phosphorylation of ULK1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in decreased expression of and results in decreased phosphorylation of ULK1 protein] |
CTD |
PMID:27106530 PMID:33002460 |
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NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963
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G |
Uspl1 |
ubiquitin specific peptidase like 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of USPL1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 5:149,121,338...149,152,246
Ensembl chr 5:149,121,160...149,152,244
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G |
Uvrag |
UV radiation resistance associated gene |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of UVRAG mRNA] |
CTD |
PMID:29307831 |
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NCBI chr 7:98,535,949...98,790,373
Ensembl chr 7:98,534,228...98,790,348
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of VCAM1 protein]] Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] |
CTD |
PMID:12615669 PMID:19281832 PMID:19642688 PMID:25876056 PMID:26901245 PMID:35349355 More...
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NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
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G |
Vdac1 |
voltage-dependent anion channel 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-monochloropropane-1, 2 diol ester results in increased expression of VDAC1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of VDAC1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [VDAC1 protein binds to VDAC1 protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of VDAC1 protein]; Acetylcysteine inhibits the reaction [quinocetone promotes the reaction [VDAC1 protein binds to VDAC1 protein]]; Acetylcysteine inhibits the reaction [quinocetone results in increased expression of VDAC1 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of VDAC1 protein] |
CTD |
PMID:22858589 PMID:23711929 PMID:28343033 PMID:38408632 |
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NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224
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G |
Vdac2 |
voltage-dependent anion channel 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [quinocetone promotes the reaction [VDAC2 protein binds to VDAC2 protein]] |
CTD |
PMID:29229420 |
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NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947
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G |
Vegfa |
vascular endothelial growth factor A |
decreases secretion multiple interactions decreases expression |
ISO EXP |
Acetylcysteine results in decreased secretion of VEGFA protein Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in decreased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA mRNA]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in decreased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of VEGFA protein] Acetylcysteine results in decreased expression of VEGFA mRNA Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of VEGFA protein] |
CTD |
PMID:11214823 PMID:11641398 PMID:11886167 PMID:13679210 PMID:15788408 PMID:16309584 PMID:16757516 PMID:17992120 PMID:18829485 PMID:18930813 PMID:19176594 PMID:19622383 PMID:19910455 PMID:20850416 PMID:21804221 PMID:27856279 PMID:30878009 PMID:35430258 More...
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NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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G |
Vegfb |
vascular endothelial growth factor B |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of VEGFB mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019
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G |
Vim |
vimentin |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of VIM protein]; Acetylcysteine inhibits the reaction [propiconazole results in increased expression of VIM protein] Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in increased expression of VIM protein] Acetylcysteine results in decreased expression of VIM protein |
CTD |
PMID:28284859 PMID:32659284 PMID:32687844 PMID:33131013 PMID:34170130 PMID:34687772 PMID:38488660 More...
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NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
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G |
Vmo1 |
vitelline membrane outer layer 1 homolog (chicken) |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of VMO1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of VMO1 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr11:70,404,342...70,405,442
Ensembl chr11:70,404,342...70,405,442
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G |
Vnn1 |
vanin 1 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of VNN1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241
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G |
Wnt1 |
wingless-type MMTV integration site family, member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [quinocetone results in decreased expression of WNT1 protein] |
CTD |
PMID:28343033 |
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NCBI chr15:98,687,738...98,691,711
Ensembl chr15:98,687,738...98,691,718
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G |
Wtap |
WT1 associating protein |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of WTAP mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of WTAP protein] |
CTD |
PMID:31004932 |
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NCBI chr17:13,185,686...13,211,430
Ensembl chr17:13,185,683...13,213,056
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G |
Xbp1 |
X-box binding protein 1 |
increases splicing multiple interactions |
ISO EXP |
Acetylcysteine results in increased splicing of XBP1 mRNA Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of XBP1 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased splicing of XBP1 mRNA] Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of XBP1 protein alternative form]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of XBP1 protein alternative form]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of XBP1 protein alternative form]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of XBP1 protein alternative form] Acetylcysteine inhibits the reaction [cinnamaldehyde inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA]]; Acetylcysteine inhibits the reaction [Doxorubicin inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA]]; Acetylcysteine inhibits the reaction [Ethylmercury Compounds results in increased splicing of XBP1 mRNA]; Acetylcysteine inhibits the reaction [shikonin inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA]]; Acetylcysteine inhibits the reaction [toxoflavin inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA]]; Acetylcysteine inhibits the reaction [XBP1 protein inhibits the reaction [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine inhibits the reaction [XBP1 protein inhibits the reaction [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species]] |
CTD |
PMID:19722195 PMID:21138464 PMID:21145380 PMID:21911445 PMID:25451595 PMID:27511942 PMID:30633982 PMID:31330229 PMID:35840659 PMID:37692514 More...
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NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions |
ISO |
[MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine] |
CTD |
PMID:23009681 |
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NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
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G |
Xiap |
X-linked inhibitor of apoptosis |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in decreased expression of XIAP protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with vorinostat] results in decreased expression of XIAP protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of XIAP protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of XIAP protein] |
CTD |
PMID:15173093 PMID:19679660 PMID:21310227 PMID:22578287 |
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NCBI chr X:41,148,483...41,198,541
Ensembl chr X:41,148,556...41,198,533
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G |
Xrcc1 |
X-ray repair complementing defective repair in Chinese hamster cells 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of XRCC1 mRNA] Acetylcysteine inhibits the reaction [XRCC1 gene mutant form results in decreased abundance of Adenosine Triphosphate]; Acetylcysteine inhibits the reaction [XRCC1 gene mutant form results in increased abundance of Malondialdehyde]; Acetylcysteine promotes the reaction [XRCC1 protein results in decreased abundance of Malondialdehyde]; Acetylcysteine promotes the reaction [XRCC1 protein results in decreased oxidation of Glutathione]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased abundance of Adenosine Triphosphate]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased activity of CAT protein]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of CYTB mRNA]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of ND2 mRNA]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of ND5 mRNA] |
CTD |
PMID:18948301 PMID:30998386 |
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NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865
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G |
Xrcc3 |
X-ray repair complementing defective repair in Chinese hamster cells 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of XRCC3 mRNA] |
CTD |
PMID:18948301 |
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NCBI chr12:111,769,626...111,780,326
Ensembl chr12:111,769,626...111,780,307
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G |
Xrcc6 |
X-ray repair complementing defective repair in Chinese hamster cells 6 |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of XRCC6 mRNA] |
CTD |
PMID:26332274 |
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NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286
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G |
Ywhah |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]] |
CTD |
PMID:33131013 |
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NCBI chr 5:33,176,160...33,185,310
Ensembl chr 5:33,176,160...33,185,310
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G |
Yy1 |
YY1 transcription factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 mRNA]; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 protein] |
CTD |
PMID:34310962 |
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NCBI chr12:108,758,841...108,786,074
Ensembl chr12:108,758,899...108,786,074
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G |
Zbtb16 |
zinc finger and BTB domain containing 16 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ZBTB16 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:48,563,097...48,747,525
Ensembl chr 9:48,565,597...48,747,522
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G |
Zdhhc19 |
zinc finger, DHHC domain containing 19 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ZDHHC19 mRNA |
CTD |
PMID:22129741 |
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NCBI chr16:32,315,059...32,326,032
Ensembl chr16:32,315,083...32,380,784
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G |
Zfand2a |
zinc finger, AN1-type domain 2A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of ZFAND2A mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 5:139,456,971...139,470,246
Ensembl chr 5:139,456,966...139,470,304
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G |
Zfhx4 |
zinc finger homeodomain 4 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ZFHX4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:5,276,268...5,480,921
Ensembl chr 3:5,283,586...5,480,917
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G |
Zfp36l2 |
zinc finger protein 36, C3H type-like 2 |
increases expression |
ISO |
Acetylcysteine results in increased expression of ZFP36L2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr17:84,491,352...84,495,375
Ensembl chr17:84,491,359...84,495,375
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G |
Zfp395 |
zinc finger protein 395 |
multiple interactions |
ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ZFP395 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:65,595,796...65,636,379
Ensembl chr14:65,595,838...65,636,379
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G |
Zkscan14 |
zinc finger with KRAB and SCAN domains 14 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of ZNF394 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 5:145,131,756...145,140,972
Ensembl chr 5:145,131,756...145,138,678
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G |
Zmym2 |
zinc finger, MYM-type 2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of ZMYM2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr14:57,123,986...57,199,815
Ensembl chr14:57,124,110...57,200,158
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G |
Cyp2d22 |
cytochrome P450, family 2, subfamily d, polypeptide 22 |
affects abundance |
ISO |
CYP2D6 affects the abundance of S-phenyl-N-acetylcysteine |
CTD |
PMID:10780264 |
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NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
ISO |
[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of S-phenyl-N-acetylcysteine |
CTD |
PMID:15051535 |
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NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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G |
Gstm1 |
glutathione S-transferase, mu 1 |
multiple interactions affects abundance |
ISO |
[GSTM1 polymorphism co-treated with Smoke] affects the abundance of S-phenyl-N-acetylcysteine; GSTA1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]; GSTT1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine] GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine; GSTM1 polymorphism affects the abundance of S-phenyl-N-acetylcysteine |
CTD |
PMID:17056211 PMID:20100551 PMID:21300142 |
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NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
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G |
Gstt1 |
glutathione S-transferase, theta 1 |
multiple interactions affects abundance affects chemical synthesis |
ISO |
[GSTT1 gene SNP affects the metabolism of Benzene] which affects the abundance of S-phenyl-N-acetylcysteine; GSTT1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine] GSTT1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine; GSTT1 polymorphism affects the abundance of S-phenyl-N-acetylcysteine GSTT1 protein polymorphism affects the chemical synthesis of S-phenyl-N-acetylcysteine |
CTD |
PMID:15533900 PMID:15935803 PMID:20100551 PMID:21300142 PMID:30086327 |
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NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
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G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
affects abundance |
ISO |
NQO1 affects the abundance of S-phenyl-N-acetylcysteine; NQO1 polymorphism affects the abundance of S-phenyl-N-acetylcysteine |
CTD |
PMID:10780264 PMID:12798093 |
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NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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