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Gene: Esr2 (estrogen receptor 2 (beta)) Mus musculus
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Symbol: Esr2
Name: estrogen receptor 2 (beta)
Description: Exhibits DNA binding activity. Involved in several processes, including hormone-mediated signaling pathway; nervous system development; and reproductive structure development. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); autoimmune hypersensitivity disease (multiple); hypospadias; and neurodegenerative disease (multiple). Is expressed in several structures, including central nervous system; genitourinary system; heart mesentery; limb segment; and mammary gland primordium. Orthologous to human ESR2 (estrogen receptor 2); PARTICIPATES IN bisphenol A response pathway; estrogen signaling pathway; tamoxifen pharmacodynamics pathway; INTERACTS WITH (25R)-cholest-5-ene-3beta,26-diol; (S)-naringenin; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ER beta; ER-beta; ER[b]; ERbeta; Estrb; estrogen receptor beta; nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta
Orthologs:
Homo sapiens (human) : ESR2 (estrogen receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Esr2 (estrogen receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Esr2 (estrogen receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ESR2 (estrogen receptor 2)
Canis lupus familiaris (dog) : ESR2 (estrogen receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Esr2 (estrogen receptor 2)
Sus scrofa (pig) : ESR2 (estrogen receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381276,120,419 - 76,177,259 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371277,221,406 - 77,278,246 (-)NCBIGRCm37mm9NCBIm37
MGSCv361277,039,259 - 77,096,099 (-)NCBImm8
Celera1277,215,189 - 77,271,340 (-)NCBICelera
Cytogenetic Map12 C3NCBI
cM Map1233.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Esr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10552
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.