Becn1 (beclin 1, autophagy related) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Becn1 (beclin 1, autophagy related) Mus musculus
Analyze
Symbol: Becn1
Name: beclin 1, autophagy related
RGD ID: 736173
MGI Page MGI
Description: Enables identical protein binding activity and protein-macromolecule adaptor activity. Involved in autophagosome assembly; cellular response to glucose starvation; and engulfment of apoptotic cell. Acts upstream of or within several processes, including amyloid-beta metabolic process; negative regulation of autophagosome assembly; and positive regulation of cardiac muscle hypertrophy. Located in autophagosome; phagocytic vesicle; and trans-Golgi network. Part of phosphatidylinositol 3-kinase complex, class III. Is active in cytoplasm. Is expressed in several structures, including brain; extraembryonic visceral endoderm; jaw; oral epithelium; and sensory organ. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Machado-Joseph disease and breast cancer. Orthologous to human BECN1 (beclin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4921513J16Rik; 5430417M23Rik; Atg; Atg6; Bcl-2-interacting protein beclin; beclin-1; coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; MGC6843
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,179,084 - 101,193,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)EnsemblGRCm39 Ensembl
GRCm3811101,288,258 - 101,302,286 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,149,581 - 101,163,581 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,067,439 - 102,081,397 (-)NCBIMGSCv36mm8
MGSCv3611101,104,357 - 101,118,357 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1164.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 83 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1MouseAcute Experimental Pancreatitis treatmentIEP 11560530 RGD 
Becn1Mouseacute necrotizing pancreatitis  ISORGD:6201906483068protein:increased expression:pancreasRGD 
Becn1Mousealcoholic cardiomyopathy treatmentIEP 407532638 RGD 
Becn1Mousealcoholic hepatitis  IEP 407445926protein:increased expression:liverRGD 
Becn1MouseAlcoholic Liver Diseases  IEP 407445926protein:increased expression:liverRGD 
Becn1MouseAlzheimer's disease  IDA 6483102 RGD 
Becn1MouseAlzheimer's disease  ISORGD:7334406483101protein:decreased expression:gray matterRGD 
Becn1Mouseamyotrophic lateral sclerosis  IEP 11561951mRNA:increased expression:spinal cordRGD 
Becn1Mouseanterior ischemic optic neuropathy  ISORGD:6201906483070protein:decreased expression:retinaRGD 
Becn1MouseBarrett's esophagus  ISORGD:62019011561943 RGD 
Becn1MouseBarrett's esophagus disease_progressionISORGD:73344011561943 RGD 
Becn1MouseBrain Hypoxia-Ischemia  ISORGD:6201906483050protein:increased expression:cerebral cortexRGD 
Becn1MouseBrain Hypoxia-Ischemia  ISORGD:62019011558017protein:increased expression:brainRGD 
Becn1Mousebrain infarction  ISORGD:6201906483057protein:increased expression:brainRGD 
Becn1MouseBrain Injuries  IEP 6483314protein:increased expression:brainRGD 
Becn1MouseBrain Injuries  ISORGD:62019011558018protein:increased expression:hippocampusRGD 
Becn1MouseBrain Injuries  ISORGD:6201906483098protein:increased expression:neuron, astrocyteRGD 
Becn1Mousebrain ischemia  ISORGD:6201906483313protein:increased expression:hippocampus, frontal cortexRGD 
Becn1Mousebrain ischemia  ISORGD:6201906483094 RGD 
Becn1Mousebreast cancer disease_progressionISORGD:733440155641236 RGD 
1 to 20 of 83 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1MouseBrain Injuries  ISORGD:73344011554173CTD Direct Evidence: therapeuticCTDPMID:34929507
Becn1MouseColonic Neoplasms  ISORGD:73344011554173CTD Direct Evidence: marker/mechanismCTDPMID:20876807
Becn1MouseLewy body dementia  ISORGD:73344011554173CTD Direct Evidence: marker/mechanismCTDPMID:19628769
Becn1MouseLung Neoplasms  ISORGD:73344011554173CTD Direct Evidence: therapeuticCTDPMID:22481206|PMID:23790316
Becn1Mousemyocardial infarction  ISORGD:73344011554173CTD Direct Evidence: marker/mechanismCTDPMID:20079142
Becn1MouseSpinal Cord Injuries  ISORGD:73344011554173CTD Direct Evidence: marker/mechanismCTDPMID:29793971
Becn1Mousestatus epilepticus  ISORGD:73344011554173CTD Direct Evidence: marker/mechanismCTDPMID:19138675
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1Mousesystemic lupus erythematosus  IAGP 13592920OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 more ...MouseDO 

1 to 20 of 727 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1Mouse(+)-pilocarpine multiple interactionsISORGD:6201906480464Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 mRNA]; Vitamin E more ...CTDPMID:19138675
Becn1Mouse(+)-pilocarpine increases expressionISORGD:6201906480464Pilocarpine results in increased expression of BECN1 mRNA; Pilocarpine results in increased expression of BECN1 more ...CTDPMID:17971868|PMID:19138675
Becn1Mouse(+)-taxifolin multiple interactionsISORGD:6201906480464alogliptin promotes the reaction [taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in more ...CTDPMID:33840231|PMID:33882723|PMID:35465754
Becn1Mouse(+)-Tetrandrine increases expressionISORGD:7334406480464tetrandrine results in increased expression of BECN1 proteinCTDPMID:26822499|PMID:30123091
Becn1Mouse(+)-Tetrandrine multiple interactionsISORGD:7334406480464[sodium arsenite co-treated with tetrandrine] results in increased expression of BECN1 proteinCTDPMID:30123091
Becn1Mouse(+)-Tetrandrine decreases expressionISORGD:7334406480464tetrandrine results in decreased expression of BECN1 proteinCTDPMID:25266202
Becn1Mouse(-)-alpha-phellandrene increases phosphorylationISORGD:7334406480464alpha phellandrene results in increased phosphorylation of BECN1 proteinCTDPMID:25649747
Becn1Mouse(-)-anisomycin multiple interactionsISORGD:6201906480464Anisomycin promotes the reaction [Colistin results in increased expression of BECN1 protein]CTDPMID:28842171
Becn1Mouse(-)-citrinin increases expressionEXP 6480464Citrinin results in increased expression of BECN1 mRNACTDPMID:22771370
Becn1Mouse(-)-epigallocatechin 3-gallate increases expressionISORGD:7334406480464epigallocatechin gallate results in increased expression of BECN1 proteinCTDPMID:32512070
Becn1Mouse(-)-epigallocatechin 3-gallate multiple interactionsEXP 6480464epigallocatechin gallate inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased more ...CTDPMID:34740634
Becn1Mouse(1->4)-beta-D-glucan multiple interactionsEXP 6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of BECN1 mRNACTDPMID:36331819
Becn1Mouse(20S)-ginsenoside Rg3 multiple interactionsISORGD:73344064804643-methyladenine inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Cisplatin results in decreased expression of more ...CTDPMID:34423507
Becn1Mouse(20S)-ginsenoside Rg3 multiple interactionsEXP 6480464ginsenoside Rg3 inhibits the reaction [Cisplatin results in decreased expression of BECN1 protein]CTDPMID:34423507
Becn1Mouse(S)-nicotine multiple interactionsEXP 6480464Nicotine promotes the reaction [Dextran Sulfate results in increased expression of BECN1 protein]CTDPMID:31926917
Becn1Mouse(S)-nicotine increases expressionEXP 6480464Nicotine results in increased expression of BECN1 mRNACTDPMID:30605750
Becn1Mouse(S)-nicotine multiple interactionsISORGD:7334406480464dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in increased expression of more ...CTDPMID:31926917
Becn1Mouse(S)-ropivacaine multiple interactionsISORGD:7334406480464Ropivacaine inhibits the reaction [3-methyladenine results in decreased expression of BECN1 protein]CTDPMID:36193553
Becn1Mouse(S)-ropivacaine increases expressionISORGD:7334406480464Ropivacaine results in increased expression of BECN1 proteinCTDPMID:36193553
Becn1Mouse1,2-dimethylhydrazine multiple interactionsEXP 6480464[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BECN1 mRNACTDPMID:22206623

1 to 20 of 727 rows

Biological Process
1 to 20 of 115 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1Mouseamyloid-beta metabolic process acts_upstream_of_or_withinIMPMGI:26836962290270 PMID:18497889MGIPMID:18497889
Becn1Mouseangiogenesis involved_inTAS 2290270 PMID:23184933UniProtPMID:23184933
Becn1Mouseapoptotic process involved_inIEAUniProtKB-KW:KW-00532290270 UniProtGO_REF:0000043
Becn1Mouseautophagosome assembly  ISORGD:6201909068941 RGDPMID:16420522|REF_RGD_ID:1643189
Becn1Mouseautophagosome assembly involved_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mouseautophagosome assembly involved_inISORGD:6201902290270 GO_CentralGO_REF:0000096
Becn1Mouseautophagosome assembly involved_inIMP 2290270 PMID:23332761UniProtPMID:23332761
Becn1Mouseautophagosome assembly involved_inIBAPANTHER:PTN000298965|UniProtKB:Q14457|MGI:1891828|RGD:620190|TAIR:locus:20767152290270 GO_CentralGO_REF:0000033
Becn1Mouseautophagosome maturation involved_inISOComplexPortal:CPX-732290270 ComplexPortalGO_REF:0000114
Becn1Mouseautophagosome maturation involved_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mouseautophagy  ISORGD:6201909068941 RGDPMID:16697404|PMID:25238224|REF_RGD_ID:11558011|REF_RGD_ID:1643194
Becn1Mouseautophagy involved_inIDA 2290270 PMID:23364696, PMID:23629966, PMID:25891078CAFAPMID:23364696|PMID:23629966|PMID:25891078
Becn1Mouseautophagy involved_inISORGD:6201902290270 GO_CentralGO_REF:0000096
Becn1Mouseautophagy involved_inISSUniProtKB:Q144572290270 UniProtGO_REF:0000024
Becn1Mouseautophagy acts_upstream_of_or_withinIDA 2290270 PMID:12372286, PMID:17589504MGIPMID:12372286|PMID:17589504
Becn1Mouseautophagy acts_upstream_of_or_withinISOUniProtKB:Q144572290270 PMID:28747345MGIPMID:28747345
Becn1Mouseautophagy involved_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mousecell division involved_inIEAUniProtKB-KW:KW-01322290270 UniProtGO_REF:0000043
Becn1Mousecellular response to aluminum ion  ISORGD:6201909068941 RGDPMID:22138567|REF_RGD_ID:6483058
Becn1Mousecellular response to aluminum ion involved_inIEAUniProtKB:Q91XJ1|ensembl:ENSRNOP000000719662290270 EnsemblGO_REF:0000107
1 to 20 of 115 rows

Cellular Component
1 to 20 of 31 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1Mouseautophagosome located_inIDA 2290270 PMID:23798385MGIPMID:23798385
Becn1Mousecytoplasm is_active_inIDA 2290270 PMID:22498477UniProtPMID:22498477
Becn1Mousecytoplasm located_inIDA 2290270 PMID:17589504MGIPMID:17589504
Becn1Mousecytoplasm located_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mousecytoplasmic side of mitochondrial outer membrane located_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mousecytoplasmic side of mitochondrial outer membrane located_inIEAUniProtKB:Q14457|ensembl:ENSP000004653642290270 EnsemblGO_REF:0000107
Becn1Mousecytoplasmic vesicle located_inIDA 2290270 PMID:12372286MGIPMID:12372286
Becn1Mousecytoskeleton located_inISS 2290270 PMID:9765397MGIPMID:9765397
Becn1Mousecytosol located_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mousecytosol located_inIEAUniProtKB:A0A024R1X5|UniProtKB:Q14457|ensembl:ENSP000004653642290270 EnsemblGO_REF:0000107
Becn1Mousedendrite located_inISORGD:6201902290270 GO_CentralGO_REF:0000096
Becn1Mousedendrite located_inIEAUniProtKB:Q91XJ1|ensembl:ENSRNOP000000719662290270 EnsemblGO_REF:0000107
Becn1Mousedendrite  ISORGD:6201909068941 RGDPMID:21490676|REF_RGD_ID:6483070
Becn1Mouseendoplasmic reticulum located_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mouseendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00972290270 UniProtGO_REF:0000044
Becn1Mouseendosome located_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mouseendosome membrane located_inIEAUniProtKB-SubCell:SL-01002290270 UniProtGO_REF:0000044
Becn1Mousemembrane located_inISS 2290270 PMID:9765397MGIPMID:9765397
Becn1Mousemitochondrion located_inISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mousenuclear body located_inIEAUniProtKB:A0A024R1X5|UniProtKB:Q14457|ensembl:ENSP000004653642290270 EnsemblGO_REF:0000107
1 to 20 of 31 rows

Molecular Function
1 to 20 of 28 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1MouseGTPase binding enablesIEAUniProtKB:Q14457|ensembl:ENSP000004653642290270 EnsemblGO_REF:0000107
Becn1MouseGTPase binding enablesISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mouseidentical protein binding enablesIPIPR:O885972290270 PMID:27994061MGIPMID:27994061
Becn1Mousemolecular adaptor activity enablesISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mousephosphatidylinositol 3-kinase binding enablesIBAPANTHER:PTN000298965|UniProtKB:Q144572290270 GO_CentralGO_REF:0000033
Becn1Mousephosphatidylinositol 3-kinase binding enablesISOUniProtKB:Q144572290270 GO_CentralGO_REF:0000119
Becn1Mousephosphatidylinositol 3-kinase binding enablesIEAUniProtKB:Q14457|ensembl:ENSP000004653642290270 EnsemblGO_REF:0000107
Becn1Mouseprotein binding enablesIPIUniProtKB:P10417|UniProtKB:P631582290270 PMID:20819940IntActPMID:20819940
Becn1Mouseprotein binding enablesIPIPR:Q9QUM42290270 PMID:22493499MGIPMID:22493499
Becn1Mouseprotein binding enablesIPIPR:Q9JK482290270 PMID:17891140MGIPMID:17891140
Becn1Mouseprotein binding enablesIPIPR:P34152|PR:Q6PF93|PR:Q8CDJ3|PR:Q8K2452290270 PMID:27994061MGIPMID:27994061
Becn1Mouseprotein binding enablesIPIPR:A2AH222290270 PMID:17589504MGIPMID:17589504
Becn1Mouseprotein binding enablesIPIPR:Q8BH602290270 PMID:12372286MGIPMID:12372286
Becn1Mouseprotein binding enablesIPIUniProtKB:Q8BH602290270 PMID:12372286IntActPMID:12372286
Becn1Mouseprotein binding enablesIPIUniProtKB:P104172290270 PMID:22258505, PMID:23629966, PMID:29849149IntActPMID:22258505|PMID:23629966|PMID:29849149
Becn1Mouseprotein binding enablesIPIUniProtKB:A2AU722290270 PMID:34428398UniProtPMID:34428398
Becn1Mouseprotein binding enablesIPIUniProtKB:Q6PF93|UniProtKB:Q8VCQ32290270 PMID:24849286IntActPMID:24849286
Becn1Mouseprotein binding  ISORGD:6213309068941 RGDPMID:25117440|REF_RGD_ID:11552604
Becn1Mouseprotein binding enablesIPIUniProtKB:Q6PF932290270 PMID:23332761, PMID:23974797IntActPMID:23332761|PMID:23974797
Becn1Mouseprotein kinase binding enablesIEAUniProtKB:Q14457|ensembl:ENSP000004653642290270 EnsemblGO_REF:0000107
1 to 20 of 28 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1Mouseautophagy pathway   ISORGD:7334301643329 RGD 
Becn1Mouseautophagy pathway   ISORGD:7334304889529 RGD 
Becn1Mouseautophagy pathway   ISORGD:6201901643194 RGD 
Becn1Mousemitochondrial autophagy pathway   ISORGD:73344010401098 RGD 

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1Mouseinositol metabolic pathway  ISORGD:73344010402751 SMPDBSMP:00011
Becn1Mousephosphoinositide metabolic pathway  ISORGD:73344010402751 SMPDBSMP:00463

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1Mouseautophagy pathway   IEA 6907045 KEGGmmu:04140
1 to 20 of 81 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Becn1Mouseabnormal amnion morphology  IAGP 5509061 MGIPMID:14657337
Becn1Mouseabnormal brain development  IAGP 5509061 MGIPMID:21464117
Becn1Mouseabnormal CD4-positive, alpha-beta T cell physiology  IAGP 5509061 MGIPMID:21660048
Becn1Mouseabnormal circulating chemokine level  IAGP 5509061 MGIPMID:27096368
Becn1Mouseabnormal heart development  IAGP 5509061 MGIPMID:21464117
Becn1Mouseabnormal immune system morphology  IAGP 5509061 MGIPMID:14638851
Becn1Mouseabnormal kidney morphology  IAGP 5509061 MGIPMID:27096368
Becn1Mouseabnormal macrophage physiology  IAGP 5509061 MGIPMID:27096368
Becn1Mouseabnormal mammary gland duct morphology  IAGP 5509061 MGIPMID:14638851
Becn1Mouseabnormal ovary morphology  IAGP 5509061 MGIPMID:21464117
Becn1Mouseabnormal primordial ovarian follicle morphology  IAGP 5509061 MGIPMID:21464117
Becn1Mouseabnormal regulatory T cell physiology  IAGP 5509061 MGIPMID:33355624
Becn1Mouseabnormal renal glomerulus morphology  IAGP 5509061 MGIPMID:27096368
Becn1Mouseabnormal spleen morphology  IAGP 5509061 MGIPMID:27096368
Becn1Mouseabsent amniotic folds  IAGP 5509061 MGIPMID:14657337
Becn1Mouseamyloid beta deposits  IAGP 5509061 MGIPMID:28806762
Becn1Mousedecreased body weight  IAGP 5509061 MGIPMID:27096368
Becn1Mousedecreased CD4-positive, alpha-beta T cell number  IAGP 5509061 MGIPMID:21660048
Becn1Mousedecreased CD8-positive, alpha-beta T cell number  IAGP 5509061 MGIPMID:21660048
Becn1Mousedecreased circulating HDL cholesterol level  IEA 5509061 MGI 
1 to 20 of 81 rows

1 to 20 of 90 rows
#
Reference Title
Reference Citation
1. Dysregulated Autophagy and Lysosome Function Are Linked to Exosome Production by Micro-RNA 155 in Alcoholic Liver Disease. Babuta M, etal., Hepatology. 2019 Dec;70(6):2123-2141. doi: 10.1002/hep.30766. Epub 2019 Jun 24.
2. Hypoxia-inducible factor-1alpha (HIF-1alpha) and autophagy in polycystic kidney disease (PKD). Belibi F, etal., Am J Physiol Renal Physiol. 2011 May;300(5):F1235-43. Epub 2011 Jan 26.
3. High Beclin-1 and ARID1A expression corelates with poor survival and high recurrence in intrahepatic cholangiocarcinoma: a histopathological retrospective study. Bi C, etal., BMC Cancer. 2019 Mar 8;19(1):213. doi: 10.1186/s12885-019-5429-3.
4. Autophagy is upregulated in rats with status epilepticus and partly inhibited by Vitamin E. Cao L, etal., Biochem Biophys Res Commun. 2009 Feb 20;379(4):949-53. Epub 2009 Jan 10.
5. Noggin attenuates cerulein-induced acute pancreatitis and impaired autophagy. Cao Y, etal., Pancreas. 2013 Mar;42(2):301-7. doi: 10.1097/MPA.0b013e31825b9f2c.
6. Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis. Carames B, etal., Arthritis Rheum. 2010 Mar;62(3):791-801.
7. Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons. Castillo K, etal., Autophagy. 2013 Sep;9(9):1308-20. doi: 10.4161/auto.25188. Epub 2013 Jun 6.
8. Cold ischemia-induced autophagy in rat lung tissue. Chen X, etal., Mol Med Rep. 2015 Apr;11(4):2513-9. doi: 10.3892/mmr.2014.2999. Epub 2014 Nov 26.
9. Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats. Cui D, etal., PLoS One. 2012;7(4):e35324. doi: 10.1371/journal.pone.0035324. Epub 2012 Apr 11.
10. Closed head injury induces upregulation of Beclin 1 at the cortical site of injury. Diskin T, etal., J Neurotrauma. 2005 Jul;22(7):750-62.
11. Ascorbic acid ameliorates seizures and brain damage in rats through inhibiting autophagy. Dong Y, etal., Brain Res. 2013 Oct 16;1535:115-23. doi: 10.1016/j.brainres.2013.08.039. Epub 2013 Aug 28.
12. Neurodegeneration induces upregulation of Beclin 1. Erlich S, etal., Autophagy. 2006 Jan-Mar;2(1):49-51. Epub 2006 Jan 8.
13. Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach. Fedorova LV, etal., BMC Nephrol. 2013 Oct 4;14:209. doi: 10.1186/1471-2369-14-209.
14. Paraplegia increases skeletal muscle autophagy. Fry CS, etal., Muscle Nerve. 2012 Nov;46(5):793-8. doi: 10.1002/mus.23423.
15. Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans. Gassen NC, etal., PLoS Med. 2014 Nov 11;11(11):e1001755. doi: 10.1371/journal.pmed.1001755. eCollection 2014 Nov.
16. Valproic acid reduces autophagy and promotes functional recovery after spinal cord injury in rats. Hao HH, etal., Neurosci Bull. 2013 Aug;29(4):484-92. doi: 10.1007/s12264-013-1355-6. Epub 2013 Jul 13.
17. Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Hariharan N, etal., Antioxid Redox Signal. 2011 Jun;14(11):2179-90. doi: 10.1089/ars.2010.3488. Epub 2011 Jan 27.
18. Roux-en-Y gastric bypass reduces lipid overaccumulation in liver by upregulating hepatic autophagy in obese diabetic rats. He B, etal., Obes Surg. 2015 Jan;25(1):109-18. doi: 10.1007/s11695-014-1342-7.
19. The preventive effect of liraglutide on the lipotoxic liver injury via increasing autophagy. He Y, etal., Ann Hepatol. 2020 Jan - Feb;19(1):44-52. doi: 10.1016/j.aohep.2019.06.023. Epub 2019 Sep 24.
20. Acute spinal cord injury in rats should target activated autophagy. Hou H, etal., J Neurosurg Spine. 2014 May;20(5):568-77. doi: 10.3171/2014.1.SPINE13237. Epub 2014 Feb 21.
1 to 20 of 90 rows
1 to 10 of 27 rows
PMID:9610637   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12372286   PMID:12477932   PMID:14610273   PMID:14638851   PMID:15131264   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16467569   PMID:16522639   PMID:16602821   PMID:16969128   PMID:17332429   PMID:17350577   PMID:17468177   PMID:17510285   PMID:17540004   PMID:17589504   PMID:17606641  
PMID:17607355   PMID:17786023   PMID:17786025   PMID:17891140   PMID:17940279   PMID:18451870   PMID:18497881   PMID:18570871   PMID:18621691   PMID:18772134   PMID:18806760   PMID:18843052  
PMID:18948195   PMID:19015235   PMID:19049976   PMID:19176312   PMID:19270693   PMID:19270696   PMID:19520853   PMID:19654319   PMID:20421418   PMID:20498061   PMID:20501938   PMID:20819940  
PMID:20935509   PMID:20947830   PMID:21139567   PMID:21151103   PMID:21217818   PMID:21239722   PMID:21367693   PMID:21368103   PMID:21444671   PMID:21464117   PMID:21479246   PMID:21611191  
PMID:21660048   PMID:21677750   PMID:21681844   PMID:21685724   PMID:21737790   PMID:21746920   PMID:21873635   PMID:21911604   PMID:21926971   PMID:21972018   PMID:21976705   PMID:22022281  
PMID:22144182   PMID:22157765   PMID:22240590   PMID:22258505   PMID:22294621   PMID:22302984   PMID:22351764   PMID:22371349   PMID:22393062   PMID:22440612   PMID:22493499   PMID:22498477  
PMID:22558309   PMID:22592897   PMID:22742832   PMID:22751932   PMID:22753949   PMID:22843615   PMID:22904094   PMID:23011054   PMID:23115045   PMID:23184933   PMID:23195496   PMID:23197835  
PMID:23308102   PMID:23332761   PMID:23341467   PMID:23364696   PMID:23380905   PMID:23569248   PMID:23589298   PMID:23611643   PMID:23629966   PMID:23650262   PMID:23658055   PMID:23685627  
PMID:23737459   PMID:23793984   PMID:23798385   PMID:23825228   PMID:23894198   PMID:23954414   PMID:23971531   PMID:23974797   PMID:24012002   PMID:24056303   PMID:24141421   PMID:24177427  
1 to 10 of 27 rows



Becn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,179,084 - 101,193,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)EnsemblGRCm39 Ensembl
GRCm3811101,288,258 - 101,302,286 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,149,581 - 101,163,581 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,067,439 - 102,081,397 (-)NCBIMGSCv36mm8
MGSCv3611101,104,357 - 101,118,357 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1164.58NCBI
BECN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,810,132 - 42,824,282 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,810,134 - 42,833,350 (-)EnsemblGRCh38hg38GRCh38
GRCh371740,962,150 - 40,976,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,215,678 - 38,229,807 (-)NCBINCBI36Build 36hg18NCBI36
Build 341738,215,677 - 38,229,807NCBI
Celera1737,618,135 - 37,632,364 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1736,726,539 - 36,740,774 (-)NCBIHuRef
CHM1_11741,197,767 - 41,211,922 (-)NCBICHM1_1
T2T-CHM13v2.01743,667,271 - 43,682,705 (-)NCBIT2T-CHM13v2.0
Becn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,731,649 - 86,747,002 (-)NCBIGRCr8
mRatBN7.21086,231,387 - 86,246,742 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,231,388 - 86,246,742 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,269,132 - 91,284,493 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,743,662 - 90,759,021 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,136,830 - 86,152,190 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,209,944 - 89,225,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,209,940 - 89,225,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,008,975 - 89,024,328 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,317,957 - 90,333,329 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11090,332,322 - 90,347,231 (-)NCBI
Celera1084,949,343 - 84,964,691 (-)NCBICelera
Cytogenetic Map10q31NCBI
Becn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,616,595 - 16,625,730 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,616,595 - 16,625,731 (-)NCBIChiLan1.0ChiLan1.0
BECN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,152,390 - 22,175,667 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,042,657 - 24,065,785 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,493,619 - 14,507,809 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,719,781 - 14,733,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,719,781 - 14,733,286 (+)Ensemblpanpan1.1panPan2
BECN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,204,203 - 20,215,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,204,220 - 20,214,236 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,665,517 - 19,676,150 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,922,592 - 20,933,221 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,922,586 - 20,933,212 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,707,479 - 19,718,113 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,973,720 - 19,984,352 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,076,426 - 20,087,053 (+)NCBIUU_Cfam_GSD_1.0
Becn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,544,014 - 19,557,039 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,517,751 - 17,531,151 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,518,100 - 17,531,126 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BECN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,041,956 - 20,054,373 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,041,914 - 20,054,249 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,256,871 - 20,268,928 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BECN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,469,187 - 63,482,627 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,469,192 - 63,485,322 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,260,316 - 34,273,836 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Becn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,385,756 - 1,405,714 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,386,154 - 1,406,314 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Becn1
323 total Variants

Predicted Target Of
Summary Value
Count of predictions:3880
Count of miRNA genes:885
Interacting mature miRNAs:1221
Transcripts:ENSMUST00000041403, ENSMUST00000122817, ENSMUST00000126195, ENSMUST00000129863, ENSMUST00000130916, ENSMUST00000135805, ENSMUST00000136535, ENSMUST00000137614, ENSMUST00000139669, ENSMUST00000139997, ENSMUST00000140286, ENSMUST00000140706, ENSMUST00000164036, ENSMUST00000167667, ENSMUST00000167818, ENSMUST00000170502, ENSMUST00000172233
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 53 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse

1 to 10 of 53 rows
RH127824  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,288,447 - 101,288,657UniSTSGRCm38
MGSCv3711101,149,761 - 101,149,971UniSTSGRCm37
Cytogenetic Map11DUniSTS
PMC299911P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,303,162 - 101,303,417UniSTSGRCm38
MGSCv3711101,164,476 - 101,164,731UniSTSGRCm37
Cytogenetic Map11DUniSTS
RH48446  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,291,396 - 101,291,518UniSTSGRCm38
MGSCv3711101,152,710 - 101,152,832UniSTSGRCm37
Cytogenetic Map11DUniSTS






1 to 29 of 29 rows
RefSeq Transcripts NM_001359819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF077302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL590969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB723507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DS033671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 29 of 29 rows

Ensembl Acc Id: ENSMUST00000041403   ⟹   ENSMUSP00000040094
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,112 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,286 (-)Ensembl
Ensembl Acc Id: ENSMUST00000122817
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,086 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,260 (-)Ensembl
Ensembl Acc Id: ENSMUST00000126195   ⟹   ENSMUSP00000122168
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,209 - 101,187,133 (-)Ensembl
GRCm38.p6 Ensembl11101,291,383 - 101,296,307 (-)Ensembl
Ensembl Acc Id: ENSMUST00000129863   ⟹   ENSMUSP00000116580
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,181,310 - 101,192,563 (-)Ensembl
GRCm38.p6 Ensembl11101,290,484 - 101,301,737 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130916   ⟹   ENSMUSP00000119369
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)Ensembl
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)Ensembl
Ensembl Acc Id: ENSMUST00000135805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,180,706 - 101,183,324 (-)Ensembl
GRCm38.p6 Ensembl11101,289,880 - 101,292,498 (-)Ensembl
Ensembl Acc Id: ENSMUST00000136535
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,714 - 101,184,867 (-)Ensembl
GRCm38.p6 Ensembl11101,288,888 - 101,294,041 (-)Ensembl
Ensembl Acc Id: ENSMUST00000137614
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,192,287 - 101,193,067 (-)Ensembl
GRCm38.p6 Ensembl11101,301,461 - 101,302,241 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139669
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,188,903 - 101,193,081 (-)Ensembl
GRCm38.p6 Ensembl11101,298,077 - 101,302,255 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139997
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,078 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,252 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140286
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,356 - 101,186,262 (-)Ensembl
GRCm38.p6 Ensembl11101,291,530 - 101,295,436 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140706   ⟹   ENSMUSP00000122412
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,186,373 - 101,193,032 (-)Ensembl
GRCm38.p6 Ensembl11101,295,547 - 101,302,206 (-)Ensembl
Ensembl Acc Id: ENSMUST00000164036
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,187,052 - 101,193,066 (-)Ensembl
GRCm38.p6 Ensembl11101,296,226 - 101,302,240 (-)Ensembl
Ensembl Acc Id: ENSMUST00000167667   ⟹   ENSMUSP00000130951
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,702 - 101,193,063 (-)Ensembl
GRCm38.p6 Ensembl11101,288,876 - 101,302,237 (-)Ensembl
Ensembl Acc Id: ENSMUST00000167818   ⟹   ENSMUSP00000131629
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,325 - 101,193,064 (-)Ensembl
GRCm38.p6 Ensembl11101,291,499 - 101,302,238 (-)Ensembl
Ensembl Acc Id: ENSMUST00000170502   ⟹   ENSMUSP00000128413
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,186,733 - 101,193,075 (-)Ensembl
GRCm38.p6 Ensembl11101,295,907 - 101,302,249 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172233   ⟹   ENSMUSP00000129156
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,244 - 101,193,077 (-)Ensembl
GRCm38.p6 Ensembl11101,288,418 - 101,302,251 (-)Ensembl
RefSeq Acc Id: NM_001359819   ⟹   NP_001346748
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359820   ⟹   NP_001346749
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359821   ⟹   NP_001346750
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,186,733 - 101,193,112 (-)NCBI
GRCm3811101,295,907 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_019584   ⟹   NP_062530
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
MGSCv3711101,149,581 - 101,163,581 (-)RGD
cM Map11 ENTREZGENE
Sequence:
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: NP_062530   ⟸   NM_019584
- Peptide Label: isoform 1
- UniProtKB: Q99J03 (UniProtKB/Swiss-Prot),   O88597 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001346748   ⟸   NM_001359819
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001346749   ⟸   NM_001359820
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001346750   ⟸   NM_001359821
- Peptide Label: isoform 4
- UniProtKB: E9QAM0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000128413   ⟸   ENSMUST00000170502
Atg6 BARA   Atg6/beclin coiled-coil   Beclin-1 BH3

Name Modeler Protein Id AA Range Protein Structure
AF-O88597-F1-model_v2 AlphaFold O88597 1-448 view protein structure

RGD ID:6820490
Promoter ID:MM_KWN:9879
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000005620,   OTTMUST00000005621,   OTTMUST00000005623,   OTTMUST00000005624,   OTTMUST00000005625,   OTTMUST00000005628,   OTTMUST00000083459,   UC007LOL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611101,163,306 - 101,163,806 (-)MPROMDB
RGD ID:8676788
Promoter ID:EPDNEW_M16424
Type:initiation region
Name:Becn1_1
Description:Mus musculus beclin 1, autophagy related , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811101,302,256 - 101,302,316EPDNEW


1 to 30 of 30 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000035086 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000130916 ENTREZGENE
  ENSMUST00000130916.8 UniProtKB/Swiss-Prot
  ENSMUST00000170502 ENTREZGENE
Gene3D-CATH 1.10.418.40 UniProtKB/Swiss-Prot
  6.10.250.3110 UniProtKB/Swiss-Prot
InterPro Atg6/Beclin UniProtKB/Swiss-Prot
  Atg6/Beclin_C_sf UniProtKB/Swiss-Prot
  Atg6/beclin_CC UniProtKB/Swiss-Prot
  Atg6_BARA UniProtKB/Swiss-Prot
  BH3_dom UniProtKB/Swiss-Prot
KEGG Report mmu:56208 UniProtKB/Swiss-Prot
MGD MGI:1891828 ENTREZGENE
NCBI Gene 56208 ENTREZGENE
PANTHER PTHR12768 UniProtKB/Swiss-Prot
  PTHR12768:SF6 UniProtKB/Swiss-Prot
Pfam APG6 UniProtKB/Swiss-Prot
  APG6_N UniProtKB/Swiss-Prot
  BH3 UniProtKB/Swiss-Prot
PhenoGen Becn1 PhenoGen
UniProt BECN1_MOUSE UniProtKB/Swiss-Prot
  E9PX06_MOUSE UniProtKB/TrEMBL
  E9PYD6_MOUSE UniProtKB/TrEMBL
  E9QAM0 ENTREZGENE, UniProtKB/TrEMBL
  F7C090_MOUSE UniProtKB/TrEMBL
  F7CVL9_MOUSE UniProtKB/TrEMBL
  F7DB15_MOUSE UniProtKB/TrEMBL
  O88597 ENTREZGENE
  Q99J03 ENTREZGENE
UniProt Secondary Q99J03 UniProtKB/Swiss-Prot
1 to 30 of 30 rows