Becn1 (beclin 1, autophagy related) - Rat Genome Database

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Gene: Becn1 (beclin 1, autophagy related) Mus musculus
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Symbol: Becn1
Name: beclin 1, autophagy related
RGD ID: 736173
MGI Page MGI
Description: Enables identical protein binding activity. Involved in several processes, including autophagy of mitochondrion; cellular response to glucose starvation; and engulfment of apoptotic cell. Acts upstream of or within several processes, including amyloid-beta metabolic process; negative regulation of autophagosome assembly; and positive regulation of cardiac muscle hypertrophy. Located in autophagosome; phagocytic vesicle; and trans-Golgi network. Part of phosphatidylinositol 3-kinase complex, class III. Is expressed in central nervous system; extraembryonic visceral endoderm; sensory organ; and spleen. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Machado-Joseph disease. Orthologous to human BECN1 (beclin 1); PARTICIPATES IN autophagy pathway; inositol metabolic pathway; mitochondrial autophagy pathway; INTERACTS WITH (-)-citrinin; (S)-nicotine; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4921513J16Rik; 5430417M23Rik; Atg; Atg6; Bcl-2-interacting protein beclin; beclin-1; coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; MGC6843
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,179,084 - 101,193,112 (-)NCBIGRCm39mm39
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)Ensembl
GRCm3811101,288,258 - 101,302,286 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,149,581 - 101,163,581 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611102,067,439 - 102,081,397 (-)NCBImm8
MGSCv3611101,104,357 - 101,118,357 (-)NCBImm8
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (IEP)
acute necrotizing pancreatitis  (ISO)
Alzheimer's disease  (IDA,ISO)
amyotrophic lateral sclerosis  (IEP)
anterior ischemic optic neuropathy  (ISO)
Barrett's esophagus  (ISO)
brain infarction  (ISO)
Brain Injuries  (IEP,ISO)
brain ischemia  (ISO)
Burns  (ISO)
Cardiomegaly  (ISO)
Cerebral Hemorrhage  (ISO)
Chronic Intermittent Hypoxia  (ISO)
Colonic Neoplasms  (ISO)
congestive heart failure  (ISO)
degenerative disc disease  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
end stage renal disease  (ISO)
epilepsy  (ISO)
esophagus adenocarcinoma  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Seizures  (ISO)
glaucoma  (ISO)
glioblastoma  (ISO)
Head Injuries, Closed  (IEP)
Heat Stroke  (ISO)
Hyperalgesia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
intrahepatic cholangiocarcinoma  (ISO)
ischemia  (ISO)
Kidney Reperfusion Injury  (ISO)
Lewy body dementia  (ISO)
liver cirrhosis  (ISO)
Lung Neoplasms  (ISO)
Machado-Joseph disease  (IEP,ISO)
mental depression  (IEP,ISO)
middle cerebral artery infarction  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (IMP,ISO)
Neointima  (ISO)
Nerve Degeneration  (ISO)
osteoarthritis  (IEP,ISO)
Osteoarthritis, Experimental  (ISO)
paraplegia  (ISO)
Parkinsonism  (IMP,ISO)
perinatal necrotizing enterocolitis  (ISO)
peritonitis  (ISO)
polycystic kidney disease  (IEP,ISO)
Reperfusion Injury  (ISO)
schizophrenia  (ISO)
Spinal Cord Injuries  (IEP,ISO)
Spinal Cord Reperfusion Injury  (ISO)
status epilepticus  (ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (IEA)
Temporomandibular Joint Disorders  (ISO)
Temporomandibular Joint Osteoarthritis  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
ureteral obstruction  (ISO)
viral encephalitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(+)-Tetrandrine  (ISO)
(-)-anisomycin  (ISO)
(-)-citrinin  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
1,4-benzoquinone  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,6-dinitrotoluene  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxyethyl methacrylate  (ISO)
2-hydroxypropanoic acid  (ISO)
3-hydroxybutyric acid  (ISO)
3-methyladenine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (EXP,ISO)
7,12-dimethyltetraphene  (ISO)
ABT-737  (ISO)
acadesine  (EXP)
actinomycin D  (EXP)
AICA ribonucleotide  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha,alpha-trehalose  (EXP)
alpha-D-galactose  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
apigenin  (EXP)
apocynin  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP,ISO)
atorvastatin calcium  (EXP)
atrazine  (EXP,ISO)
azinphos-methyl  (ISO)
bafilomycin A1  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
beta-thujaplicin  (EXP)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
brazilin  (ISO)
butyric acid  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP,ISO)
calciol  (ISO)
calcipotriol  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
cannabidiol  (EXP,ISO)
Cannabidivarin  (EXP)
capsaicin  (ISO)
captan  (EXP)
carbon disulfide  (EXP)
carbon nanotube  (EXP,ISO)
carboplatin  (ISO)
carglumic acid  (EXP)
carmustine  (ISO)
carvedilol  (ISO)
CCCP  (EXP,ISO)
celastrol  (ISO)
CGS-21680  (ISO)
chloroquine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
choline  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
colistin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
Corynoxine B  (ISO)
cucurbitacin E  (ISO)
Curcumol  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
dapagliflozin  (ISO)
DDE  (EXP)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (EXP)
diquat  (EXP)
disodium selenite  (ISO)
divinyl sulfone  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
embelin  (ISO)
endosulfan  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
ferric oxide  (EXP)
fingolimod hydrochloride  (ISO)
fisetin  (EXP)
fluoxetine  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
galactose  (ISO)
galangin  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gingerol  (ISO)
glucose  (EXP,ISO)
glycerol 2-phosphate  (ISO)
glycochenodeoxycholic acid  (ISO)
glyphosate  (ISO)
gossypetin  (ISO)
graphene oxide  (EXP,ISO)
graphite  (ISO)
hesperidin  (ISO)
hexadecanoic acid  (EXP,ISO)
HU-308  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
kainic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
L-leucine  (EXP)
L-methionine  (EXP)
lead diacetate  (ISO)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
levamisole  (EXP)
linuron  (ISO)
lipopolysaccharide  (EXP,ISO)
luteolin  (ISO)
LY294002  (ISO)
lycopene  (EXP)
maneb  (EXP)
manganese(II) chloride  (ISO)
Maprotiline  (ISO)
Matrine  (ISO)
melatonin  (ISO)
menadione  (ISO)
methamidophos  (ISO)
methamphetamine  (EXP,ISO)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
microcystin-LR  (EXP)
morphine  (ISO)
morpholines  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methylnicotinate  (EXP,ISO)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nicotine  (EXP,ISO)
Nonidet P-40  (ISO)
oleanolic acid  (ISO)
oligopeptide  (ISO)
omethoate  (ISO)
ozone  (ISO)
p-cresol  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
Paeonol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentachlorophenol  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphoramide mustard  (ISO)
platycodin D  (ISO)
potassium iodide  (ISO)
procyanidin B2  (EXP)
promethazine  (ISO)
pyrovalerone  (ISO)
pyruvic acid  (ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
Rhein  (ISO)
rotenone  (EXP,ISO)
rottlerin  (ISO)
salubrinal  (ISO)
SB 203580  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP,ISO)
sirolimus  (EXP,ISO)
SKF-96365 hydrochloride  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sodium fluoride  (EXP,ISO)
spironolactone  (ISO)
staurosporine  (ISO)
streptozocin  (EXP)
sulfur dioxide  (ISO)
sunitinib  (EXP,ISO)
swainsonine  (ISO)
syringic acid  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
tetramethylpyrazine  (EXP)
thalidomide  (ISO)
Tiron  (ISO)
titanium dioxide  (EXP,ISO)
tributylstannane  (ISO)
trifloxystrobin  (ISO)
Triptolide  (EXP)
triptonide  (EXP)
ursolic acid  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vitamin D  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
WIN 55212-2  (ISO)
wortmannin  (ISO)
zearalenone  (EXP,ISO)
zinc oxide  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
amyloid-beta metabolic process  (IMP)
angiogenesis  (TAS)
apoptotic process  (IEA)
autophagosome assembly  (IBA,IMP,ISO)
autophagosome maturation  (ISO)
autophagy  (IDA,ISO)
autophagy of mitochondrion  (IMP,ISO)
cell division  (IEA)
cellular response to aluminum ion  (ISO)
cellular response to amino acid starvation  (ISO)
cellular response to copper ion  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to glucose starvation  (IDA)
cellular response to hydrogen peroxide  (ISO)
cellular response to nitrogen starvation  (IBA)
defense response to virus  (IEA)
early endosome to late endosome transport  (ISO)
endocytosis  (IEA)
engulfment of apoptotic cell  (IMP)
late endosome to vacuole transport  (IBA)
lysosome organization  (IMP)
macroautophagy  (IGI,IMP)
mitophagy  (ISO)
mitotic metaphase plate congression  (ISO)
negative regulation of apoptotic process  (IMP,ISO)
negative regulation of autophagosome assembly  (IMP)
negative regulation of autophagy  (IMP)
negative regulation of cell death  (ISO)
negative regulation of cell population proliferation  (IDA)
negative regulation of lysosome organization  (ISO)
negative regulation of reactive oxygen species metabolic process  (IMP)
neuron development  (IMP)
phosphatidylinositol-3-phosphate biosynthetic process  (ISO)
positive regulation of attachment of mitotic spindle microtubules to kinetochore  (ISO)
positive regulation of autophagosome assembly  (ISO)
positive regulation of autophagy  (ISO)
positive regulation of cardiac muscle hypertrophy  (IMP)
positive regulation of intrinsic apoptotic signaling pathway  (ISO)
protein phosphorylation  (ISO)
receptor catabolic process  (ISO)
regulation of autophagy  (ISO)
regulation of catalytic activity  (IMP)
regulation of cytokinesis  (ISO)
regulation of macroautophagy  (ISO)
response to hypoxia  (ISO)
response to iron(II) ion  (ISO)
response to lead ion  (ISO)
response to mitochondrial depolarisation  (ISO)
response to nutrient levels  (ISO)
response to other organism  (IDA)
response to vitamin E  (ISO)
response to xenobiotic stimulus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal amnion morphology  (IAGP)
abnormal brain development  (IAGP)
abnormal CD4-positive, alpha-beta T cell physiology  (IAGP)
abnormal circulating chemokine level  (IAGP)
abnormal heart development  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal mammary gland duct morphology  (IAGP)
abnormal ovary morphology  (IAGP)
abnormal primordial ovarian follicle morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal spleen morphology  (IAGP)
absent amniotic folds  (IAGP)
amyloid beta deposits  (IAGP)
decreased body weight  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating HDL cholesterol level  (IEA)
decreased circulating interleukin-10 level  (IAGP)
decreased embryo size  (IAGP)
decreased lean body mass  (IEA)
decreased myocardial infarct size  (IAGP)
decreased primordial ovarian follicle number  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased T cell proliferation  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enhanced autophagy  (IAGP)
extended life span  (IAGP)
glomerulonephritis  (IAGP)
impaired autophagy  (IAGP)
impaired exercise endurance  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased anti-nuclear antigen antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased B cell derived lymphoma incidence  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased circulating bilirubin level  (IEA)
increased circulating creatinine level  (IAGP)
increased circulating interleukin-1 beta level  (IAGP)
increased circulating interleukin-12b level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased embryonic tissue cell apoptosis  (IAGP)
increased follicular lymphoma incidence  (IAGP)
increased hepatocellular carcinoma incidence  (IAGP)
increased histiocytic sarcoma incidence  (IAGP)
increased IgG level  (IAGP)
increased leukocyte cell number  (IEA)
increased lung adenocarcinoma incidence  (IAGP)
increased lung adenoma incidence  (IAGP)
increased lung carcinoma incidence  (IAGP)
increased lymphocyte cell number  (IAGP)
increased lymphoma incidence  (IAGP)
increased malignant tumor incidence  (IAGP)
increased mammary gland tumor incidence  (IAGP)
increased monocyte cell number  (IAGP)
increased myocardial infarct size  (IAGP)
increased neutrophil cell number  (IAGP)
increased plasmacytoma incidence  (IAGP)
increased spleen germinal center number  (IAGP)
increased spleen germinal center size  (IAGP)
increased startle reflex  (IEA)
increased susceptibility to systemic lupus erythematosus  (IAGP)
increased T cell apoptosis  (IAGP)
increased total body fat amount  (IEA)
increased tumor incidence  (IAGP)
increased urine protein level  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
small ovary  (IAGP)
References

References - curated
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54. RGD automated import pipeline for gene-chemical interactions
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Additional References at PubMed
PMID:9610637   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12372286   PMID:12477932   PMID:14610273   PMID:14638851   PMID:15131264   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16522639   PMID:16602821   PMID:16969128   PMID:17332429   PMID:17350577   PMID:17468177   PMID:17510285   PMID:17540004   PMID:17589504   PMID:17606641   PMID:17607355  
PMID:17786023   PMID:17786025   PMID:17891140   PMID:17940279   PMID:18281291   PMID:18451870   PMID:18497881   PMID:18570871   PMID:18621691   PMID:18772134   PMID:18806760   PMID:18843052  
PMID:18948195   PMID:19015235   PMID:19049976   PMID:19176312   PMID:19270693   PMID:19270696   PMID:19520853   PMID:19654319   PMID:20421418   PMID:20498061   PMID:20501938   PMID:20819940  
PMID:20935509   PMID:20947830   PMID:21139567   PMID:21151103   PMID:21217818   PMID:21239722   PMID:21367693   PMID:21368103   PMID:21444671   PMID:21464117   PMID:21479246   PMID:21611191  
PMID:21660048   PMID:21677750   PMID:21681844   PMID:21685724   PMID:21737790   PMID:21746920   PMID:21873635   PMID:21911604   PMID:21926971   PMID:21972018   PMID:21976705   PMID:22022281  
PMID:22144182   PMID:22157765   PMID:22240590   PMID:22258505   PMID:22294621   PMID:22302984   PMID:22351764   PMID:22371349   PMID:22393062   PMID:22440612   PMID:22493499   PMID:22558309  
PMID:22592897   PMID:22742832   PMID:22751932   PMID:22753949   PMID:22843615   PMID:23011054   PMID:23115045   PMID:23184933   PMID:23195496   PMID:23197835   PMID:23308102   PMID:23332761  
PMID:23341467   PMID:23364696   PMID:23380905   PMID:23569248   PMID:23589298   PMID:23611643   PMID:23629966   PMID:23650262   PMID:23658055   PMID:23685627   PMID:23737459   PMID:23793984  
PMID:23798385   PMID:23825228   PMID:23894198   PMID:23971531   PMID:23974797   PMID:24012002   PMID:24056303   PMID:24141421   PMID:24177427   PMID:24200693   PMID:24324270   PMID:24386307  
PMID:24458007   PMID:24550138   PMID:24550300   PMID:24569637   PMID:24771295   PMID:24849286   PMID:24879156   PMID:24905722   PMID:24988431   PMID:25086229   PMID:25188513   PMID:25246579  
PMID:25275521   PMID:25350163   PMID:25366815   PMID:25472497   PMID:25483966   PMID:25484083   PMID:25561470   PMID:25586377   PMID:25714272   PMID:25837021   PMID:25915474   PMID:26098576  
PMID:26209658   PMID:26235979   PMID:26295339   PMID:26386349   PMID:26456737   PMID:26494620   PMID:26590968   PMID:26636486   PMID:26692002   PMID:26732594   PMID:26764599   PMID:26800655  
PMID:26905199   PMID:26984939   PMID:27021405   PMID:27035618   PMID:27036871   PMID:27096368   PMID:27149384   PMID:27295610   PMID:27304906   PMID:27407143   PMID:27513923   PMID:27636016  
PMID:27737765   PMID:27994061   PMID:27997827   PMID:28079883   PMID:28088783   PMID:28129024   PMID:28193861   PMID:28246202   PMID:28347844   PMID:28407687   PMID:28409693   PMID:28445460  
PMID:28474670   PMID:28542134   PMID:28643395   PMID:28682313   PMID:28747345   PMID:28806762   PMID:28964771   PMID:28973896   PMID:29056340   PMID:29297752   PMID:29311744   PMID:29329412  
PMID:29551680   PMID:29604308   PMID:29610308   PMID:29724354   PMID:29752681   PMID:29844467   PMID:29849149   PMID:29853517   PMID:29898399   PMID:29996716   PMID:30232271   PMID:30245008  
PMID:30617086   PMID:30635942   PMID:30686098   PMID:30701202   PMID:30807795   PMID:31059511   PMID:31074883   PMID:31115481   PMID:31162135   PMID:31257024   PMID:31267272   PMID:31346084  
PMID:31373534   PMID:31399521   PMID:31503548   PMID:31508820   PMID:31522342   PMID:31908016   PMID:31908069   PMID:31923184   PMID:31937766   PMID:31959973   PMID:31984794   PMID:32051584  
PMID:32093570   PMID:32340512   PMID:32344065   PMID:32358527   PMID:32372061   PMID:32421784   PMID:32468217   PMID:32498399   PMID:32757698   PMID:32840757   PMID:32891637   PMID:32984329  
PMID:33046512   PMID:33058849   PMID:33277741   PMID:33355624   PMID:33369168   PMID:33510463   PMID:33737502   PMID:33751937   PMID:33818629   PMID:34038729   PMID:34048907   PMID:34180401  
PMID:34211859   PMID:34238932   PMID:34359998  


Genomics

Comparative Map Data
Becn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,179,084 - 101,193,112 (-)NCBIGRCm39mm39
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)Ensembl
GRCm3811101,288,258 - 101,302,286 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,149,581 - 101,163,581 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611102,067,439 - 102,081,397 (-)NCBImm8
MGSCv3611101,104,357 - 101,118,357 (-)NCBImm8
Cytogenetic Map11DNCBI
BECN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1742,810,134 - 42,833,350 (-)EnsemblGRCh38hg38GRCh38
GRCh381742,810,132 - 42,824,282 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371740,962,150 - 40,976,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,215,678 - 38,229,807 (-)NCBINCBI36hg18NCBI36
Build 341738,215,677 - 38,229,807NCBI
Celera1737,618,135 - 37,632,364 (-)NCBI
Cytogenetic Map17q21.31NCBI
HuRef1736,726,539 - 36,740,774 (-)NCBIHuRef
CHM1_11741,197,767 - 41,211,922 (-)NCBICHM1_1
Becn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21086,231,387 - 86,246,742 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1086,231,388 - 86,246,742 (-)Ensembl
Rnor_6.01089,209,944 - 89,225,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,209,940 - 89,225,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,008,975 - 89,024,328 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,317,957 - 90,333,329 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11090,332,322 - 90,347,231 (-)NCBI
Celera1084,949,343 - 84,964,691 (-)NCBICelera
Cytogenetic Map10q31NCBI
Becn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,616,595 - 16,625,730 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,616,595 - 16,625,731 (-)NCBIChiLan1.0ChiLan1.0
BECN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11714,719,781 - 14,733,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,719,781 - 14,733,286 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01714,493,619 - 14,507,809 (+)NCBIMhudiblu_PPA_v0panPan3
BECN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,204,203 - 20,215,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,204,220 - 20,214,236 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,665,517 - 19,676,150 (+)NCBI
ROS_Cfam_1.0920,922,592 - 20,933,221 (+)NCBI
UMICH_Zoey_3.1919,707,479 - 19,718,113 (+)NCBI
UNSW_CanFamBas_1.0919,973,720 - 19,984,352 (+)NCBI
UU_Cfam_GSD_1.0920,076,426 - 20,087,053 (+)NCBI
Becn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,544,014 - 19,557,039 (+)NCBI
SpeTri2.0NW_00493649017,518,100 - 17,531,126 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BECN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,041,956 - 20,054,373 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,041,914 - 20,054,249 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,256,871 - 20,268,928 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BECN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,469,187 - 63,482,627 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,469,192 - 63,485,322 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607734,260,316 - 34,273,836 (+)NCBIVero_WHO_p1.0
Becn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247951,386,154 - 1,406,314 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH127824  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,288,447 - 101,288,657UniSTSGRCm38
MGSCv3711101,149,761 - 101,149,971UniSTSGRCm37
Cytogenetic Map11DUniSTS
PMC299911P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,303,162 - 101,303,417UniSTSGRCm38
MGSCv3711101,164,476 - 101,164,731UniSTSGRCm37
Cytogenetic Map11DUniSTS
RH48446  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,291,396 - 101,291,518UniSTSGRCm38
MGSCv3711101,152,710 - 101,152,832UniSTSGRCm37
Cytogenetic Map11DUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179922933104611872Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1181000000102000000Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185954085119954085Mouse
15039374Adip29_madiposity 29 (mouse)1186717494120717494Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186717494120717494Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186717494120717494Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187600000126900000Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187611774121611872Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187800372103383289Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189978425122082543Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191713782122082543Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191713782122082543Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1193048547112653728Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193338357122082543Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194172953118131898Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194300000119000000Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94546357118131898Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195513139122082543Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195513139122082543Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196246848122082543Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196285639108915558Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196919310122082543Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1197006867110713165Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198461783122082543Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198609643122082543Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199363361122082543Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100167277122082543Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100363360120996339Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101131764122082543Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir30ammu-miR-30a-5pOncomiRDBexternal_infoNANA22157765
Mir30ammu-miR-30a-5pOncomiRDBexternal_infoNANA19535919
Mir30dmmu-miR-30d-5pOncomiRDBexternal_infoNANA23274497

Predicted Target Of
Summary Value
Count of predictions:3880
Count of miRNA genes:885
Interacting mature miRNAs:1221
Transcripts:ENSMUST00000041403, ENSMUST00000122817, ENSMUST00000126195, ENSMUST00000129863, ENSMUST00000130916, ENSMUST00000135805, ENSMUST00000136535, ENSMUST00000137614, ENSMUST00000139669, ENSMUST00000139997, ENSMUST00000140286, ENSMUST00000140706, ENSMUST00000164036, ENSMUST00000167667, ENSMUST00000167818, ENSMUST00000170502, ENSMUST00000172233
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001359819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF077302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL590969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB723507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DS033671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000041403   ⟹   ENSMUSP00000040094
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,112 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,286 (-)Ensembl
RefSeq Acc Id: ENSMUST00000122817
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,086 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,260 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126195   ⟹   ENSMUSP00000122168
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,209 - 101,187,133 (-)Ensembl
GRCm38.p6 Ensembl11101,291,383 - 101,296,307 (-)Ensembl
RefSeq Acc Id: ENSMUST00000129863   ⟹   ENSMUSP00000116580
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,181,310 - 101,192,563 (-)Ensembl
GRCm38.p6 Ensembl11101,290,484 - 101,301,737 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130916   ⟹   ENSMUSP00000119369
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)Ensembl
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135805
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,180,706 - 101,183,324 (-)Ensembl
GRCm38.p6 Ensembl11101,289,880 - 101,292,498 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136535
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,714 - 101,184,867 (-)Ensembl
GRCm38.p6 Ensembl11101,288,888 - 101,294,041 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137614
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,192,287 - 101,193,067 (-)Ensembl
GRCm38.p6 Ensembl11101,301,461 - 101,302,241 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139669
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,188,903 - 101,193,081 (-)Ensembl
GRCm38.p6 Ensembl11101,298,077 - 101,302,255 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139997
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,078 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,252 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140286
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,356 - 101,186,262 (-)Ensembl
GRCm38.p6 Ensembl11101,291,530 - 101,295,436 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140706   ⟹   ENSMUSP00000122412
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,186,373 - 101,193,032 (-)Ensembl
GRCm38.p6 Ensembl11101,295,547 - 101,302,206 (-)Ensembl
RefSeq Acc Id: ENSMUST00000164036
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,187,052 - 101,193,066 (-)Ensembl
GRCm38.p6 Ensembl11101,296,226 - 101,302,240 (-)Ensembl
RefSeq Acc Id: ENSMUST00000167667   ⟹   ENSMUSP00000130951
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,702 - 101,193,063 (-)Ensembl
GRCm38.p6 Ensembl11101,288,876 - 101,302,237 (-)Ensembl
RefSeq Acc Id: ENSMUST00000167818   ⟹   ENSMUSP00000131629
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,325 - 101,193,064 (-)Ensembl
GRCm38.p6 Ensembl11101,291,499 - 101,302,238 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170502   ⟹   ENSMUSP00000128413
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,186,733 - 101,193,075 (-)Ensembl
GRCm38.p6 Ensembl11101,295,907 - 101,302,249 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172233   ⟹   ENSMUSP00000129156
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,244 - 101,193,077 (-)Ensembl
GRCm38.p6 Ensembl11101,288,418 - 101,302,251 (-)Ensembl
RefSeq Acc Id: NM_001359819   ⟹   NP_001346748
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359820   ⟹   NP_001346749
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359821   ⟹   NP_001346750
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,186,733 - 101,193,112 (-)NCBI
GRCm3811101,295,907 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_019584   ⟹   NP_062530
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
MGSCv3711101,149,581 - 101,163,581 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_062530   ⟸   NM_019584
- Peptide Label: isoform 1
- UniProtKB: O88597 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001346748   ⟸   NM_001359819
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001346749   ⟸   NM_001359820
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001346750   ⟸   NM_001359821
- Peptide Label: isoform 4
RefSeq Acc Id: ENSMUSP00000128413   ⟸   ENSMUST00000170502
RefSeq Acc Id: ENSMUSP00000119369   ⟸   ENSMUST00000130916
RefSeq Acc Id: ENSMUSP00000129156   ⟸   ENSMUST00000172233
RefSeq Acc Id: ENSMUSP00000122168   ⟸   ENSMUST00000126195
RefSeq Acc Id: ENSMUSP00000122412   ⟸   ENSMUST00000140706
RefSeq Acc Id: ENSMUSP00000116580   ⟸   ENSMUST00000129863
RefSeq Acc Id: ENSMUSP00000040094   ⟸   ENSMUST00000041403
RefSeq Acc Id: ENSMUSP00000130951   ⟸   ENSMUST00000167667
RefSeq Acc Id: ENSMUSP00000131629   ⟸   ENSMUST00000167818
Protein Domains
APG6   APG6_N   BH3

Promoters
RGD ID:6820490
Promoter ID:MM_KWN:9879
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000005620,   OTTMUST00000005621,   OTTMUST00000005623,   OTTMUST00000005624,   OTTMUST00000005625,   OTTMUST00000005628,   OTTMUST00000083459,   UC007LOL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611101,163,306 - 101,163,806 (-)MPROMDB
RGD ID:8676788
Promoter ID:EPDNEW_M16424
Type:initiation region
Name:Becn1_1
Description:Mus musculus beclin 1, autophagy related , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811101,302,256 - 101,302,316EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1891828 AgrOrtholog
Ensembl Genes ENSMUSG00000035086 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000040094 UniProtKB/TrEMBL
  ENSMUSP00000116580 UniProtKB/TrEMBL
  ENSMUSP00000119369 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000122168 UniProtKB/TrEMBL
  ENSMUSP00000122412 UniProtKB/TrEMBL
  ENSMUSP00000128413 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000129156 UniProtKB/TrEMBL
  ENSMUSP00000130951 UniProtKB/TrEMBL
  ENSMUSP00000131629 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000041403 UniProtKB/TrEMBL
  ENSMUST00000126195 UniProtKB/TrEMBL
  ENSMUST00000129863 UniProtKB/TrEMBL
  ENSMUST00000130916 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000140706 UniProtKB/TrEMBL
  ENSMUST00000167667 UniProtKB/TrEMBL
  ENSMUST00000167818 UniProtKB/TrEMBL
  ENSMUST00000170502 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000172233 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Atg6/Beclin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg6/Beclin_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg6/beclin_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg6_BARA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BECN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56208 UniProtKB/Swiss-Prot
MGD MGI:1891828 ENTREZGENE
NCBI Gene 56208 ENTREZGENE
PANTHER PTHR12768 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12768:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam APG6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  APG6_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Becn1 PhenoGen
UniProt BECN1_MOUSE UniProtKB/Swiss-Prot
  E9PX06_MOUSE UniProtKB/TrEMBL
  E9PYD6_MOUSE UniProtKB/TrEMBL
  E9QAM0_MOUSE UniProtKB/TrEMBL
  F7C090_MOUSE UniProtKB/TrEMBL
  F7CVL9_MOUSE UniProtKB/TrEMBL
  F7DB15_MOUSE UniProtKB/TrEMBL
  O88597 ENTREZGENE
UniProt Secondary Q99J03 UniProtKB/Swiss-Prot