Becn1 (beclin 1, autophagy related) - Rat Genome Database

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Gene: Becn1 (beclin 1, autophagy related) Mus musculus
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Symbol: Becn1
Name: beclin 1, autophagy related
RGD ID: 736173
MGI Page MGI
Description: Enables identical protein binding activity and protein-macromolecule adaptor activity. Involved in autophagosome assembly; cellular response to glucose starvation; and engulfment of apoptotic cell. Acts upstream of or within several processes, including amyloid-beta metabolic process; negative regulation of autophagosome assembly; and positive regulation of cardiac muscle hypertrophy. Located in autophagosome; phagocytic vesicle; and trans-Golgi network. Part of phosphatidylinositol 3-kinase complex, class III. Is active in cytoplasm. Is expressed in several structures, including brain; extraembryonic visceral endoderm; jaw; oral epithelium; and sensory organ. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Machado-Joseph disease and breast cancer. Orthologous to human BECN1 (beclin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4921513J16Rik; 5430417M23Rik; Atg; Atg6; Bcl-2-interacting protein beclin; beclin-1; coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; MGC6843
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,179,084 - 101,193,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)EnsemblGRCm39 Ensembl
GRCm3811101,288,258 - 101,302,286 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,149,581 - 101,163,581 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,067,439 - 102,081,397 (-)NCBIMGSCv36mm8
MGSCv3611101,104,357 - 101,118,357 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1164.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (IEP)
acute necrotizing pancreatitis  (ISO)
alcoholic cardiomyopathy  (IEP)
alcoholic hepatitis  (IEP)
Alcoholic Liver Diseases  (IEP)
Alzheimer's disease  (IDA,ISO)
amyotrophic lateral sclerosis  (IEP)
anterior ischemic optic neuropathy  (ISO)
Barrett's esophagus  (ISO)
Brain Hypoxia-Ischemia  (ISO)
brain infarction  (ISO)
Brain Injuries  (IEP,ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Burns  (ISO)
Cardiomegaly  (ISO)
Cerebral Hemorrhage  (ISO)
Chronic Intermittent Hypoxia  (ISO)
Closed Head Injuries  (IEP)
Colonic Neoplasms  (ISO)
congestive heart failure  (ISO)
degenerative disc disease  (ISO)
depressive disorder  (IEP,ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (IEP,ISO)
end stage renal disease  (ISO)
epilepsy  (ISO)
esophagus adenocarcinoma  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Seizures  (ISO)
glaucoma  (ISO)
glioblastoma  (ISO)
Heat Stroke  (ISO)
Hyperalgesia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
intrahepatic cholangiocarcinoma  (ISO)
ischemia  (ISO)
Kidney Reperfusion Injury  (ISO)
Lewy body dementia  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (IEP)
Lung Neoplasms  (ISO)
Machado-Joseph disease  (IEP,ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
middle cerebral artery infarction  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (IMP,ISO)
Neointima  (ISO)
Nerve Degeneration  (ISO)
osteoarthritis  (IEP,ISO)
Osteoarthritis, Experimental  (ISO)
paraplegia  (ISO)
Parkinsonism  (IMP,ISO)
perinatal necrotizing enterocolitis  (ISO)
peritonitis  (ISO)
polycystic kidney disease  (IEP,ISO)
Reperfusion Injury  (ISO)
schizophrenia  (ISO)
Spinal Cord Injuries  (IEP,ISO)
Spinal Cord Reperfusion Injury  (ISO)
status epilepticus  (ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (IAGP)
Temporomandibular Joint Disorders  (ISO)
Temporomandibular Joint Osteoarthritis  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
ureteral obstruction  (ISO)
viral encephalitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(+)-taxifolin  (ISO)
(+)-Tetrandrine  (ISO)
(-)-alpha-phellandrene  (ISO)
(-)-anisomycin  (ISO)
(-)-citrinin  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(1->4)-beta-D-glucan  (EXP)
(20S)-ginsenoside Rg3  (EXP,ISO)
(S)-nicotine  (EXP,ISO)
(S)-ropivacaine  (ISO)
1,2-dimethylhydrazine  (EXP)
1,4-benzoquinone  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-D  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxyethyl methacrylate  (ISO)
2-hydroxypropanoic acid  (ISO)
3-hydroxybutyric acid  (ISO)
3-methyladenine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (EXP,ISO)
5-methoxypsoralen  (EXP)
7,12-dimethyltetraphene  (ISO)
abamectin  (ISO)
ABT-737  (ISO)
acadesine  (EXP)
acrylamide  (EXP,ISO)
acrylonitrile  (EXP)
actinomycin D  (EXP)
Aescin  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
AICA ribonucleotide  (ISO)
aldehydo-D-glucose  (EXP,ISO)
alginic acid  (EXP)
Alisol B  (ISO)
all-trans-retinoic acid  (ISO)
alogliptin  (ISO)
alpha,alpha-trehalose  (EXP)
alpha-amanitin  (ISO)
alpha-D-galactose  (ISO)
alpha-phellandrene  (ISO)
Alpinetin  (EXP,ISO)
ammonium chloride  (ISO)
amsacrine  (ISO)
Anemoside B4  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
apigenin  (EXP)
apocynin  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
asperuloside  (EXP)
astaxanthin  (ISO)
atorvastatin calcium  (EXP)
atrazine  (EXP,ISO)
azinphos-methyl  (ISO)
bafilomycin A1  (ISO)
baicalein  (ISO)
benzo[a]pyrene  (EXP,ISO)
berberine  (EXP,ISO)
beta-lapachone  (ISO)
beta-thujaplicin  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
brazilin  (ISO)
buprofezin  (ISO)
busulfan  (EXP)
butyric acid  (ISO)
cadmium acetate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP,ISO)
calciol  (ISO)
calcipotriol  (ISO)
calcitriol  (EXP,ISO)
camptothecin  (ISO)
candesartan  (ISO)
cannabidiol  (EXP,ISO)
Cannabidivarin  (EXP)
cantharidin  (ISO)
capsaicin  (ISO)
captan  (EXP)
carbamazepine  (ISO)
carbon disulfide  (EXP)
carbon nanotube  (EXP,ISO)
carboplatin  (ISO)
carglumic acid  (EXP)
carmustine  (ISO)
carvedilol  (ISO)
CCCP  (EXP,ISO)
celastrol  (ISO)
CGS-21680  (ISO)
chloroquine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
choline  (EXP)
chromium(6+)  (EXP,ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
colistin  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
corosolic acid  (EXP)
Corynoxine B  (ISO)
crocin-1  (ISO)
cucurbitacin E  (ISO)
curcumin  (ISO)
Curcumol  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
dapagliflozin  (ISO)
DDE  (EXP)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
Dibromoacetonitrile  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dideuterium oxide  (ISO)
diethylstilbestrol  (EXP,ISO)
diisononyl phthalate  (ISO)
dioxygen  (EXP,ISO)
diprotium oxide  (EXP)
diquat  (EXP)
disodium selenite  (ISO)
disulfiram  (ISO)
divinyl sulfone  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
embelin  (ISO)
empagliflozin  (ISO)
enalapril  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
Ethyl icosapentate  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
Evodiamine  (ISO)
fenofibrate  (EXP)
ferric ammonium citrate  (ISO)
ferric oxide  (EXP)
ferrostatin-1  (ISO)
fingolimod hydrochloride  (ISO)
fisetin  (EXP)
fluoxetine  (ISO)
flutamide  (ISO)
fluvastatin  (ISO)
folic acid  (EXP)
folpet  (EXP)
Forsythiaside  (EXP)
FR900359  (ISO)
galactose  (ISO)
galangin  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gefitinib  (ISO)
gingerol  (ISO)
Ginkgoic acid  (ISO)
glucose  (EXP,ISO)
glycerol 2-phosphate  (ISO)
glycochenodeoxycholic acid  (ISO)
glyphosate  (EXP,ISO)
gossypetin  (ISO)
graphene oxide  (EXP,ISO)
graphite  (ISO)
hesperetin  (ISO)
hesperidin  (ISO)
hexadecanoic acid  (EXP,ISO)
HU-308  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
indometacin  (EXP)
inositol  (ISO)
iohexol  (EXP)
iron atom  (ISO)
iron(0)  (ISO)
Jujuboside A  (EXP)
kainic acid  (ISO)
ketamine  (EXP)
ketoconazole  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
L-leucine  (EXP)
L-methionine  (EXP)
lanthanum trichloride  (ISO)
lead diacetate  (ISO)
lead(0)  (EXP,ISO)
levamisole  (EXP)
linuron  (ISO)
lipopolysaccharide  (EXP,ISO)
luteolin  (ISO)
LY294002  (EXP,ISO)
lycopene  (EXP,ISO)
maneb  (EXP)
manganese(II) chloride  (ISO)
Maprotiline  (ISO)
melatonin  (EXP,ISO)
menadione  (ISO)
metformin  (ISO)
methamidophos  (ISO)
methamphetamine  (EXP,ISO)
methidathion  (EXP)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methylphenidate  (EXP,ISO)
microcystin-LR  (EXP)
mirtazapine  (EXP,ISO)
MitoTEMPO  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
morphine  (ISO)
morpholines  (ISO)
Morroniside  (EXP,ISO)
N(gamma)-nitro-L-arginine methyl ester  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methylnicotinate  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nickel atom  (EXP)
nickel dichloride  (EXP)
nicotine  (EXP,ISO)
Nonidet P-40  (ISO)
ochratoxin A  (ISO)
octadecanoic acid  (EXP)
octreotide  (EXP)
oleanolic acid  (ISO)
oligopeptide  (ISO)
omethoate  (ISO)
omipalisib  (ISO)
osthole  (ISO)
ozone  (EXP,ISO)
p-cresol  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
Paeonol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
patulin  (ISO)
pentachlorophenol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
perfluoroundecanoic acid  (ISO)
phenanthrene  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphoramide mustard  (ISO)
Plantamajoside  (ISO)
platycodin D  (ISO)
potassium dichromate  (ISO)
potassium iodide  (ISO)
procyanidin B2  (EXP)
promethazine  (ISO)
pterostilbene  (EXP,ISO)
pyruvic acid  (ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
Repaglinide  (ISO)
resveratrol  (ISO)
Rhein  (ISO)
rotenone  (EXP,ISO)
rottlerin  (ISO)
salubrinal  (ISO)
Sanggenon C  (ISO)
SB 203580  (ISO)
SCH772984  (ISO)
selenium atom  (ISO)
selenomethionine  (EXP)
sepantronium  (ISO)
silicon dioxide  (EXP,ISO)
Sinomenine  (ISO)
sirolimus  (EXP,ISO)
SKF-96365 hydrochloride  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sodium fluoride  (EXP,ISO)
sphingosine 1-phosphate  (ISO)
spironolactone  (ISO)
staurosporine  (ISO)
streptozocin  (EXP,ISO)
sulforaphane  (EXP)
sulfur dioxide  (ISO)
sunitinib  (EXP,ISO)
swainsonine  (EXP,ISO)
syringic acid  (ISO)
T-2 toxin  (EXP,ISO)
tadalafil  (EXP)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
tetramethylpyrazine  (EXP)
thalidomide  (ISO)
Theaflavin 3,3'-digallate  (ISO)
Tiron  (ISO)
titanium dioxide  (EXP,ISO)
toosendanin  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
trifloxystrobin  (ISO)
trifluoperazine  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
triptonide  (EXP)
tunicamycin  (ISO)
tyloxapol  (EXP)
ursolic acid  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vismodegib  (ISO)
vitamin D  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
water  (EXP)
WIN 55212-2  (ISO)
wortmannin  (ISO)
zearalenone  (EXP,ISO)
zinc oxide  (EXP,ISO)
zingerone  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
amyloid-beta metabolic process  (IMP)
angiogenesis  (TAS)
apoptotic process  (IEA)
autophagosome assembly  (IBA,IMP,ISO)
autophagosome maturation  (ISO)
autophagy  (IDA,ISO,ISS)
cell division  (IEA)
cellular response to aluminum ion  (IEA,ISO)
cellular response to amino acid starvation  (IEA,ISO)
cellular response to copper ion  (IEA,ISO)
cellular response to epidermal growth factor stimulus  (IEA,ISO)
cellular response to glucose starvation  (IDA)
cellular response to hydrogen peroxide  (IEA,ISO)
cellular response to nitrogen starvation  (IBA)
cellular response to oxygen-glucose deprivation  (IEA,ISO)
circadian rhythm  (ISO)
cytoplasmic pattern recognition receptor signaling pathway  (IEA,ISO)
defense response to virus  (IEA)
early endosome to late endosome transport  (ISO,ISS)
engulfment of apoptotic cell  (IMP)
JNK cascade  (IEA,ISO)
late endosome to vacuole transport  (IBA)
lysosome organization  (IMP)
macroautophagy  (IGI,IMP)
mitophagy  (IBA,ISO)
mitotic metaphase chromosome alignment  (IEA,ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of autophagosome assembly  (IMP)
negative regulation of autophagy  (IMP)
negative regulation of cell population proliferation  (IDA)
negative regulation of lysosome organization  (IEA,ISO)
negative regulation of programmed cell death  (ISO)
neuron development  (IMP)
p38MAPK cascade  (IEA,ISO)
phosphatidylinositol-3-phosphate biosynthetic process  (ISO)
positive regulation of attachment of mitotic spindle microtubules to kinetochore  (IEA,ISO)
positive regulation of autophagosome assembly  (IEA,ISO)
positive regulation of autophagy  (ISO,ISS)
positive regulation of cardiac muscle hypertrophy  (IMP)
positive regulation of intrinsic apoptotic signaling pathway  (ISO,ISS)
positive regulation of stress granule assembly  (IEA,ISO)
protein targeting to lysosome  (NAS)
protein-containing complex assembly  (IEA,ISO)
receptor catabolic process  (IEA,ISO)
regulation of autophagy  (ISO)
regulation of catalytic activity  (IMP)
regulation of cytokinesis  (ISO,ISS)
regulation of macroautophagy  (ISO)
response to hypoxia  (IEA,ISO)
response to iron(II) ion  (IEA,ISO)
response to lead ion  (IEA,ISO)
response to mitochondrial depolarisation  (IEA,ISO)
response to nutrient levels  (ISO)
response to other organism  (IDA)
response to vitamin E  (IEA,ISO)
response to xenobiotic stimulus  (IEA,ISO)
SMAD protein signal transduction  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal amnion morphology  (IAGP)
abnormal brain development  (IAGP)
abnormal CD4-positive, alpha-beta T cell physiology  (IAGP)
abnormal circulating chemokine level  (IAGP)
abnormal heart development  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal mammary gland duct morphology  (IAGP)
abnormal ovary morphology  (IAGP)
abnormal primordial ovarian follicle morphology  (IAGP)
abnormal regulatory T cell physiology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal spleen morphology  (IAGP)
absent amniotic folds  (IAGP)
amyloid beta deposits  (IAGP)
decreased body weight  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating HDL cholesterol level  (IEA)
decreased circulating interleukin-10 level  (IAGP)
decreased embryo size  (IAGP)
decreased lean body mass  (IEA)
decreased myocardial infarct size  (IAGP)
decreased primordial ovarian follicle number  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased T cell proliferation  (IAGP)
decreased tumor-free survival time  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enhanced autophagy  (IAGP)
extended life span  (IAGP)
glomerulonephritis  (IAGP)
impaired autophagy  (IAGP)
impaired exercise endurance  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased anti-nuclear antigen antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased B cell derived lymphoma incidence  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased circulating bilirubin level  (IEA)
increased circulating creatinine level  (IAGP)
increased circulating interleukin-1 beta level  (IAGP)
increased circulating interleukin-12b level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased embryonic tissue cell apoptosis  (IAGP)
increased follicular lymphoma incidence  (IAGP)
increased hepatocellular carcinoma incidence  (IAGP)
increased histiocytic sarcoma incidence  (IAGP)
increased IgG level  (IAGP)
increased leukocyte cell number  (IEA)
increased lung adenocarcinoma incidence  (IAGP)
increased lung adenoma incidence  (IAGP)
increased lung carcinoma incidence  (IAGP)
increased lymphocyte cell number  (IAGP)
increased lymphoma incidence  (IAGP)
increased malignant tumor incidence  (IAGP)
increased mammary gland tumor incidence  (IAGP)
increased monocyte cell number  (IAGP)
increased myocardial infarct size  (IAGP)
increased neutrophil cell number  (IAGP)
increased plasmacytoma incidence  (IAGP)
increased spleen germinal center number  (IAGP)
increased spleen germinal center size  (IAGP)
increased startle reflex  (IEA)
increased susceptibility to systemic lupus erythematosus  (IAGP)
increased T cell apoptosis  (IAGP)
increased total body fat amount  (IEA)
increased tumor incidence  (IAGP)
increased urine protein level  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
small ovary  (IAGP)
References

References - curated
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53. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
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Genomics

Comparative Map Data
Becn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,179,084 - 101,193,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)EnsemblGRCm39 Ensembl
GRCm3811101,288,258 - 101,302,286 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,149,581 - 101,163,581 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,067,439 - 102,081,397 (-)NCBIMGSCv36mm8
MGSCv3611101,104,357 - 101,118,357 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1164.58NCBI
BECN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,810,132 - 42,824,282 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,810,134 - 42,833,350 (-)EnsemblGRCh38hg38GRCh38
GRCh371740,962,150 - 40,976,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,215,678 - 38,229,807 (-)NCBINCBI36Build 36hg18NCBI36
Build 341738,215,677 - 38,229,807NCBI
Celera1737,618,135 - 37,632,364 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1736,726,539 - 36,740,774 (-)NCBIHuRef
CHM1_11741,197,767 - 41,211,922 (-)NCBICHM1_1
T2T-CHM13v2.01743,667,271 - 43,682,705 (-)NCBIT2T-CHM13v2.0
Becn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,731,649 - 86,747,002 (-)NCBIGRCr8
mRatBN7.21086,231,387 - 86,246,742 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,231,388 - 86,246,742 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,269,132 - 91,284,493 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,743,662 - 90,759,021 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,136,830 - 86,152,190 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,209,944 - 89,225,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,209,940 - 89,225,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,008,975 - 89,024,328 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,317,957 - 90,333,329 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11090,332,322 - 90,347,231 (-)NCBI
Celera1084,949,343 - 84,964,691 (-)NCBICelera
Cytogenetic Map10q31NCBI
Becn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,616,595 - 16,625,730 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,616,595 - 16,625,731 (-)NCBIChiLan1.0ChiLan1.0
BECN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,152,390 - 22,175,667 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,042,657 - 24,065,785 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,493,619 - 14,507,809 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,719,781 - 14,733,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,719,781 - 14,733,286 (+)Ensemblpanpan1.1panPan2
BECN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,204,203 - 20,215,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,204,220 - 20,214,236 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,665,517 - 19,676,150 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,922,592 - 20,933,221 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,922,586 - 20,933,212 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,707,479 - 19,718,113 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,973,720 - 19,984,352 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,076,426 - 20,087,053 (+)NCBIUU_Cfam_GSD_1.0
Becn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,544,014 - 19,557,039 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,517,751 - 17,531,151 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,518,100 - 17,531,126 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BECN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,041,956 - 20,054,373 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,041,914 - 20,054,249 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,256,871 - 20,268,928 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BECN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,469,187 - 63,482,627 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,469,192 - 63,485,322 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,260,316 - 34,273,836 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Becn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,385,756 - 1,405,714 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,386,154 - 1,406,314 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Becn1
323 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3880
Count of miRNA genes:885
Interacting mature miRNAs:1221
Transcripts:ENSMUST00000041403, ENSMUST00000122817, ENSMUST00000126195, ENSMUST00000129863, ENSMUST00000130916, ENSMUST00000135805, ENSMUST00000136535, ENSMUST00000137614, ENSMUST00000139669, ENSMUST00000139997, ENSMUST00000140286, ENSMUST00000140706, ENSMUST00000164036, ENSMUST00000167667, ENSMUST00000167818, ENSMUST00000170502, ENSMUST00000172233
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100254186120887165Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
13513919Heal56_mwound healing/ regeneration 56 (mouse)11101156468101540293Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse

Markers in Region
RH127824  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,288,447 - 101,288,657UniSTSGRCm38
MGSCv3711101,149,761 - 101,149,971UniSTSGRCm37
Cytogenetic Map11DUniSTS
PMC299911P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,303,162 - 101,303,417UniSTSGRCm38
MGSCv3711101,164,476 - 101,164,731UniSTSGRCm37
Cytogenetic Map11DUniSTS
RH48446  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811101,291,396 - 101,291,518UniSTSGRCm38
MGSCv3711101,152,710 - 101,152,832UniSTSGRCm37
Cytogenetic Map11DUniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001359819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF077302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL590969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB723507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DS033671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000041403   ⟹   ENSMUSP00000040094
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,112 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,286 (-)Ensembl
Ensembl Acc Id: ENSMUST00000122817
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,086 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,260 (-)Ensembl
Ensembl Acc Id: ENSMUST00000126195   ⟹   ENSMUSP00000122168
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,209 - 101,187,133 (-)Ensembl
GRCm38.p6 Ensembl11101,291,383 - 101,296,307 (-)Ensembl
Ensembl Acc Id: ENSMUST00000129863   ⟹   ENSMUSP00000116580
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,181,310 - 101,192,563 (-)Ensembl
GRCm38.p6 Ensembl11101,290,484 - 101,301,737 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130916   ⟹   ENSMUSP00000119369
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,176,778 - 101,193,112 (-)Ensembl
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)Ensembl
Ensembl Acc Id: ENSMUST00000135805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,180,706 - 101,183,324 (-)Ensembl
GRCm38.p6 Ensembl11101,289,880 - 101,292,498 (-)Ensembl
Ensembl Acc Id: ENSMUST00000136535
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,714 - 101,184,867 (-)Ensembl
GRCm38.p6 Ensembl11101,288,888 - 101,294,041 (-)Ensembl
Ensembl Acc Id: ENSMUST00000137614
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,192,287 - 101,193,067 (-)Ensembl
GRCm38.p6 Ensembl11101,301,461 - 101,302,241 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139669
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,188,903 - 101,193,081 (-)Ensembl
GRCm38.p6 Ensembl11101,298,077 - 101,302,255 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139997
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,088 - 101,193,078 (-)Ensembl
GRCm38.p6 Ensembl11101,288,262 - 101,302,252 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140286
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,356 - 101,186,262 (-)Ensembl
GRCm38.p6 Ensembl11101,291,530 - 101,295,436 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140706   ⟹   ENSMUSP00000122412
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,186,373 - 101,193,032 (-)Ensembl
GRCm38.p6 Ensembl11101,295,547 - 101,302,206 (-)Ensembl
Ensembl Acc Id: ENSMUST00000164036
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,187,052 - 101,193,066 (-)Ensembl
GRCm38.p6 Ensembl11101,296,226 - 101,302,240 (-)Ensembl
Ensembl Acc Id: ENSMUST00000167667   ⟹   ENSMUSP00000130951
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,702 - 101,193,063 (-)Ensembl
GRCm38.p6 Ensembl11101,288,876 - 101,302,237 (-)Ensembl
Ensembl Acc Id: ENSMUST00000167818   ⟹   ENSMUSP00000131629
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,182,325 - 101,193,064 (-)Ensembl
GRCm38.p6 Ensembl11101,291,499 - 101,302,238 (-)Ensembl
Ensembl Acc Id: ENSMUST00000170502   ⟹   ENSMUSP00000128413
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,186,733 - 101,193,075 (-)Ensembl
GRCm38.p6 Ensembl11101,295,907 - 101,302,249 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172233   ⟹   ENSMUSP00000129156
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,179,244 - 101,193,077 (-)Ensembl
GRCm38.p6 Ensembl11101,288,418 - 101,302,251 (-)Ensembl
RefSeq Acc Id: NM_001359819   ⟹   NP_001346748
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359820   ⟹   NP_001346749
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359821   ⟹   NP_001346750
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,186,733 - 101,193,112 (-)NCBI
GRCm3811101,295,907 - 101,302,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_019584   ⟹   NP_062530
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,179,084 - 101,193,112 (-)NCBI
GRCm3811101,288,258 - 101,302,286 (-)NCBI
MGSCv3711101,149,581 - 101,163,581 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_062530   ⟸   NM_019584
- Peptide Label: isoform 1
- UniProtKB: O88597 (UniProtKB/Swiss-Prot),   Q99J03 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001346748   ⟸   NM_001359819
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001346749   ⟸   NM_001359820
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001346750   ⟸   NM_001359821
- Peptide Label: isoform 4
- UniProtKB: E9QAM0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000128413   ⟸   ENSMUST00000170502
Ensembl Acc Id: ENSMUSP00000119369   ⟸   ENSMUST00000130916
Ensembl Acc Id: ENSMUSP00000129156   ⟸   ENSMUST00000172233
Ensembl Acc Id: ENSMUSP00000122168   ⟸   ENSMUST00000126195
Ensembl Acc Id: ENSMUSP00000122412   ⟸   ENSMUST00000140706
Ensembl Acc Id: ENSMUSP00000116580   ⟸   ENSMUST00000129863
Ensembl Acc Id: ENSMUSP00000040094   ⟸   ENSMUST00000041403
Ensembl Acc Id: ENSMUSP00000130951   ⟸   ENSMUST00000167667
Ensembl Acc Id: ENSMUSP00000131629   ⟸   ENSMUST00000167818
Protein Domains
Atg6 BARA   Atg6/beclin coiled-coil   Beclin-1 BH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88597-F1-model_v2 AlphaFold O88597 1-448 view protein structure

Promoters
RGD ID:6820490
Promoter ID:MM_KWN:9879
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000005620,   OTTMUST00000005621,   OTTMUST00000005623,   OTTMUST00000005624,   OTTMUST00000005625,   OTTMUST00000005628,   OTTMUST00000083459,   UC007LOL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611101,163,306 - 101,163,806 (-)MPROMDB
RGD ID:8676788
Promoter ID:EPDNEW_M16424
Type:initiation region
Name:Becn1_1
Description:Mus musculus beclin 1, autophagy related , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811101,302,256 - 101,302,316EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1891828 AgrOrtholog
Ensembl Genes ENSMUSG00000035086 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000041403.12 UniProtKB/TrEMBL
  ENSMUST00000126195.2 UniProtKB/TrEMBL
  ENSMUST00000129863.2 UniProtKB/TrEMBL
  ENSMUST00000130916 ENTREZGENE
  ENSMUST00000130916.8 UniProtKB/Swiss-Prot
  ENSMUST00000140706.8 UniProtKB/TrEMBL
  ENSMUST00000167667.8 UniProtKB/TrEMBL
  ENSMUST00000167818.8 UniProtKB/TrEMBL
  ENSMUST00000170502 ENTREZGENE
  ENSMUST00000170502.2 UniProtKB/TrEMBL
  ENSMUST00000172233.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.3110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Atg6/Beclin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg6/Beclin_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg6/beclin_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg6_BARA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56208 UniProtKB/Swiss-Prot
MGD MGI:1891828 ENTREZGENE
NCBI Gene 56208 ENTREZGENE
PANTHER PTHR12768 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12768:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam APG6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  APG6_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Becn1 PhenoGen
UniProt BECN1_MOUSE UniProtKB/Swiss-Prot
  E9PX06_MOUSE UniProtKB/TrEMBL
  E9PYD6_MOUSE UniProtKB/TrEMBL
  E9QAM0 ENTREZGENE, UniProtKB/TrEMBL
  F7C090_MOUSE UniProtKB/TrEMBL
  F7CVL9_MOUSE UniProtKB/TrEMBL
  F7DB15_MOUSE UniProtKB/TrEMBL
  O88597 ENTREZGENE
  Q99J03 ENTREZGENE
UniProt Secondary Q99J03 UniProtKB/Swiss-Prot