Atg4a (autophagy related 4A, cysteine peptidase) - Rat Genome Database

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Gene: Atg4a (autophagy related 4A, cysteine peptidase) Mus musculus
Analyze
Symbol: Atg4a
Name: autophagy related 4A, cysteine peptidase
RGD ID: 1616955
MGI Page MGI
Description: Predicted to enable cysteine-type endopeptidase activity and protein-phosphatidylethanolamide deconjugating activity. Predicted to be involved in macroautophagy and protein processing. Predicted to be active in cytoplasm. Is expressed in embryo. Orthologous to human ATG4A (autophagy related 4A cysteine peptidase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI627006; Ap; APG4 (ATG4) autophagy-related homolog A; Apg4a; Atg4al; Aut; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; Autl2; autophagin 2; autophagin-2; autophagy 4 homolog A; autophagy-related 4A; autophagy-related 4A-like; autophagy-related cysteine endopeptidase 2; autophagy-related protein 4 homolog A; AV169859; cysteine protease APG4A; cysteine protease ATG4A; MGC107179
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Atg4a-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X139,854,594 - 139,947,190 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX139,857,656 - 139,947,266 (+)EnsemblGRCm39 Ensembl
GRCm38X140,953,845 - 141,164,194 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX140,956,907 - 141,164,270 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X137,593,241 - 137,598,813 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv37X137,491,456 - 137,529,979 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X136,303,271 - 136,342,019 (+)NCBIMGSCv36mm8
CeleraX124,212,154 - 124,250,668 (+)NCBICelera
CeleraX125,167,353 - 125,172,805 (+)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX61.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
autophagy pathway  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. LC3 conjugation system in mammalian autophagy. Tanida I, etal., Int J Biochem Cell Biol. 2004 Dec;36(12):2503-18.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16602821   PMID:21267068   PMID:21873635   PMID:25652854  
PMID:25654548   PMID:26805760   PMID:28253956   PMID:36198274  


Genomics

Comparative Map Data
Atg4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X139,854,594 - 139,947,190 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX139,857,656 - 139,947,266 (+)EnsemblGRCm39 Ensembl
GRCm38X140,953,845 - 141,164,194 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX140,956,907 - 141,164,270 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X137,593,241 - 137,598,813 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv37X137,491,456 - 137,529,979 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X136,303,271 - 136,342,019 (+)NCBIMGSCv36mm8
CeleraX124,212,154 - 124,250,668 (+)NCBICelera
CeleraX125,167,353 - 125,172,805 (+)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX61.67NCBI
ATG4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X108,088,829 - 108,154,671 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX108,091,668 - 108,154,671 (+)EnsemblGRCh38hg38GRCh38
GRCh37X107,335,008 - 107,397,901 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X107,221,590 - 107,284,552 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX107,806,406 - 107,869,363 (+)NCBICelera
Cytogenetic MapXq22.3NCBI
HuRefX96,957,585 - 97,020,331 (+)NCBIHuRef
CHM1_1X107,245,775 - 107,308,734 (+)NCBICHM1_1
T2T-CHM13v2.0X106,526,530 - 106,592,262 (+)NCBIT2T-CHM13v2.0
Atg4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X109,453,712 - 109,553,758 (+)NCBIGRCr8
mRatBN7.2X104,665,345 - 104,765,271 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX104,665,345 - 104,765,268 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX106,794,654 - 106,894,585 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X110,294,013 - 110,393,796 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X107,848,029 - 107,952,306 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X112,328,907 - 112,403,157 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0352,231,912 - 52,273,743 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX104,178,429 - 104,184,592 (+)NCBICelera
Cytogenetic MapXq33NCBI
Atg4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554907,762,623 - 7,788,705 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554907,765,145 - 7,825,126 (-)NCBIChiLan1.0ChiLan1.0
ATG4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X107,572,779 - 107,636,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X107,576,410 - 107,640,195 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X97,189,556 - 97,253,371 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X107,559,639 - 107,623,389 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX107,559,639 - 107,623,389 (+)Ensemblpanpan1.1panPan2
ATG4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X81,629,346 - 81,688,086 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX81,629,465 - 81,688,099 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX67,753,046 - 67,808,661 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X83,281,769 - 83,337,418 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX83,279,008 - 83,337,403 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X80,740,818 - 80,796,428 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X82,453,368 - 82,509,012 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X82,244,510 - 82,299,838 (+)NCBIUU_Cfam_GSD_1.0
Atg4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X80,966,279 - 81,016,771 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364996,640,957 - 6,691,995 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364996,641,192 - 6,691,685 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX88,548,751 - 88,633,321 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X88,545,924 - 88,633,328 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X103,050,536 - 103,071,241 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATG4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X95,936,385 - 96,011,541 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX95,983,662 - 96,010,578 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606521,037,553 - 21,109,912 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248038,337,042 - 8,407,222 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248038,336,123 - 8,407,354 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atg4a
2312 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:781
Count of miRNA genes:464
Interacting mature miRNAs:510
Transcripts:ENSMUST00000112971, ENSMUST00000147972, ENSMUST00000153742
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
13208552Wght12_mweight 12 (mouse)X94043606149782996Mouse
13208556Lgth14_mbody length 14 (mouse)X94043606149782996Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX120993165160213038Mouse
25314309Syncl5_msynaptonemal complex length 5 (mouse)X121909697152582996Mouse
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX125685149159685269Mouse
13824981Svwq2_mseminal vesicle weight QTL 2 (mouse)X128900749153782996Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX133540040165298595Mouse
1301276Tswt_mtestis weight (mouse)Not determinedX138376411150789338Mouse

Markers in Region
AV169859  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383103,644,061 - 103,644,141UniSTSGRCm38
GRCm38X141,164,006 - 141,164,086UniSTSGRCm38
MGSCv37X137,598,549 - 137,598,629UniSTSGRCm37
MGSCv373103,447,984 - 103,448,064UniSTSGRCm37
Celera3105,852,602 - 105,852,682UniSTS
CeleraX125,172,541 - 125,172,621UniSTS
Cytogenetic MapXF1UniSTS
Cytogenetic Map3F2.2UniSTS
Whitehead/MRC_RHX1625.46UniSTS
AI627006  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383103,644,061 - 103,644,141UniSTSGRCm38
GRCm38X141,164,006 - 141,164,086UniSTSGRCm38
MGSCv37X137,598,549 - 137,598,629UniSTSGRCm37
MGSCv373103,447,984 - 103,448,064UniSTSGRCm37
Celera3105,852,602 - 105,852,682UniSTS
CeleraX125,172,541 - 125,172,621UniSTS
Cytogenetic MapXF1UniSTS
Cytogenetic Map3F2.2UniSTS
Whitehead/MRC_RHX1626.83UniSTS
px-11_b9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X140,980,505 - 140,980,607UniSTSGRCm38
MGSCv37X137,515,044 - 137,515,146UniSTSGRCm37
CeleraX124,235,716 - 124,235,818UniSTS
Cytogenetic MapXF1UniSTS
px-2b10  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X140,970,711 - 140,970,895UniSTSGRCm38
MGSCv37X137,505,250 - 137,505,434UniSTSGRCm37
CeleraX124,225,928 - 124,226,112UniSTS
Cytogenetic MapXF1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001379681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_174875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004940359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK041379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL672306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL691493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB638045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY287162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ057919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK023195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO425906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR478060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FO082333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ976858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF597730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000112971   ⟹   ENSMUSP00000108595
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX139,857,656 - 139,947,266 (+)Ensembl
GRCm38.p6 EnsemblX140,956,907 - 141,164,270 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147972
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX139,945,091 - 139,946,451 (+)Ensembl
GRCm38.p6 EnsemblX141,162,095 - 141,163,455 (+)Ensembl
RefSeq Acc Id: ENSMUST00000153742
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX139,857,699 - 139,896,189 (+)Ensembl
GRCm38.p6 EnsemblX140,956,950 - 140,992,837 (+)Ensembl
RefSeq Acc Id: ENSMUST00000239541   ⟹   ENSMUSP00000159430
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX139,857,695 - 139,947,266 (+)Ensembl
RefSeq Acc Id: ENSMUST00000239542
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX139,866,333 - 139,896,328 (+)Ensembl
RefSeq Acc Id: ENSMUST00000239543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX139,880,635 - 139,888,947 (+)Ensembl
RefSeq Acc Id: ENSMUST00000239544   ⟹   ENSMUSP00000159432
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX139,857,694 - 139,947,191 (+)Ensembl
RefSeq Acc Id: NM_001379681   ⟹   NP_001366610
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,854,594 - 139,947,190 (+)NCBI
GRCm38X140,953,845 - 141,164,194 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001379682   ⟹   NP_001366611
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,857,656 - 139,947,190 (+)NCBI
GRCm38X140,956,907 - 141,164,194 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001379683   ⟹   NP_001366612
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,857,656 - 139,947,190 (+)NCBI
GRCm38X140,956,907 - 141,164,194 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001379684   ⟹   NP_001366613
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,857,656 - 139,947,190 (+)NCBI
GRCm38X140,956,907 - 141,164,194 (+)NCBI
Sequence:
RefSeq Acc Id: NM_174875   ⟹   NP_777364
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,857,656 - 139,947,190 (+)NCBI
GRCm38X140,956,907 - 141,164,194 (+)NCBI
MGSCv37X137,491,456 - 137,529,979 (+)RGD
CeleraX125,167,354 - 125,172,805 (+)NCBI
CeleraX124,212,154 - 124,250,669 (+)NCBI
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017318600   ⟹   XP_017174089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,854,647 - 139,947,190 (+)NCBI
GRCm38X140,953,898 - 141,164,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318601   ⟹   XP_017174090
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,881,109 - 139,947,190 (+)NCBI
GRCm38X140,980,329 - 141,164,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318602   ⟹   XP_017174091
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,880,568 - 139,947,190 (+)NCBI
GRCm38X140,979,726 - 141,164,194 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004940359
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X139,854,647 - 139,947,190 (+)NCBI
Sequence:
RefSeq Acc Id: NP_777364   ⟸   NM_174875
- Peptide Label: isoform 1
- UniProtKB: Q811B8 (UniProtKB/Swiss-Prot),   Q8C9S8 (UniProtKB/Swiss-Prot),   Q5EBK1 (UniProtKB/TrEMBL),   A0A0G2JFS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174089   ⟸   XM_017318600
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JFS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174091   ⟸   XM_017318602
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JFS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174090   ⟸   XM_017318601
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JFS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001366610   ⟸   NM_001379681
- Peptide Label: isoform 2
- UniProtKB: A0A0G2JFS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001366611   ⟸   NM_001379682
- Peptide Label: isoform 3
- UniProtKB: A0A0G2JFS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001366613   ⟸   NM_001379684
- Peptide Label: isoform 5
- UniProtKB: A0A0G2JFS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001366612   ⟸   NM_001379683
- Peptide Label: isoform 4
- UniProtKB: A0A7N9VS64 (UniProtKB/TrEMBL),   A0A0G2JFS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000108595   ⟸   ENSMUST00000112971
RefSeq Acc Id: ENSMUSP00000159430   ⟸   ENSMUST00000239541
RefSeq Acc Id: ENSMUSP00000159432   ⟸   ENSMUST00000239544
Protein Domains
Peptidase C54 catalytic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C9S8-F1-model_v2 AlphaFold Q8C9S8 1-396 view protein structure

Promoters
RGD ID:13681522
Promoter ID:EPDNEW_M24910
Type:initiation region
Name:Atg4a_1
Description:Mus musculus autophagy related 4A, cysteine peptidase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X140,956,917 - 140,956,977EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2147903 AgrOrtholog
Ensembl Genes ENSMUSG00000079418 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000112971 ENTREZGENE
  ENSMUST00000112971.2 UniProtKB/Swiss-Prot
  ENSMUST00000153742.3 UniProtKB/TrEMBL
  ENSMUST00000239541 ENTREZGENE
  ENSMUST00000239541.1 UniProtKB/TrEMBL
  ENSMUST00000239544 ENTREZGENE
  ENSMUST00000239544.1 UniProtKB/TrEMBL
InterPro ATG4_LIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C54 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C54_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:666468 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2147903 ENTREZGENE
NCBI Gene 666468 ENTREZGENE
PANTHER PTHR22624 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22624:SF35 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ATG4_LIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C54 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atg4a PhenoGen
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JFS9 ENTREZGENE
  A0A7N9VS64 ENTREZGENE, UniProtKB/TrEMBL
  A0A7N9VT17_MOUSE UniProtKB/TrEMBL
  A0A7P0A158_MOUSE UniProtKB/TrEMBL
  ATG4A_MOUSE UniProtKB/Swiss-Prot
  Q5EBK1 ENTREZGENE, UniProtKB/TrEMBL
  Q811B8 ENTREZGENE
  Q8C9S8 ENTREZGENE
UniProt Secondary Q811B8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-06-19 Atg4a  autophagy related 4A, cysteine peptidase  Atg4a  autophagy-related 4A (yeast)  Symbol and/or name change 5135510 APPROVED