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Gene: Fasl (Fas ligand (TNF superfamily, member 6)) Mus musculus
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Symbol: Fasl
Name: Fas ligand (TNF superfamily, member 6)
Description: ENCODES a protein that exhibits death receptor binding (ortholog); tumor necrosis factor receptor binding (ortholog); INVOLVED IN apoptotic signaling pathway; extrinsic apoptotic signaling pathway via death domain receptors; retinal cell programmed cell death; PARTICIPATES IN extrinsic apoptotic pathway; FasL mediated signaling pathway; interleukin-12 signaling pathway; ASSOCIATED WITH Acute Liver Failure; autoimmune hepatitis; Experimental Pancreatitis, Acute ; FOUND IN cell surface; external side of plasma membrane; caveola (ortholog); INTERACTS WITH 1,2-dichloroethane; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: APT1LG1; CD178; CD95 ligand; CD95-L; CD95L; Fas antigen ligand; Fas-L; Fas-Ligand; Faslg; generalized lymphoproliferative disease; gld; Tnfsf6; Tnlg1a; tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand 1a; tumor necrosis factor ligand superfamily member 6
Orthologs:
Homo sapiens (human) : FASLG (Fas ligand)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Faslg (Fas ligand)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Faslg (Fas ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : FASLG (Fas ligand)
Canis lupus familiaris (dog) : FASLG (Fas ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Faslg (Fas ligand)
Sus scrofa (pig) : FASLG (Fas ligand (TNF superfamily, member 6))
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381161,780,691 - 161,788,495 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371163,710,820 - 163,718,626 (-)NCBIGRCm37mm9NCBIm37
MGSCv361163,617,366 - 163,625,172 (-)NCBImm8
Celera1164,235,657 - 164,243,458 (-)NCBICelera
Cytogenetic Map1 H2.1NCBI
cM Map169.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fasl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553064
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.