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Gene: Fasl (Fas ligand (TNF superfamily, member 6)) Mus musculus
Symbol: Fasl
Name: Fas ligand (TNF superfamily, member 6)
Description: ENCODES a protein that exhibits death receptor binding (ortholog); tumor necrosis factor receptor binding (ortholog); INVOLVED IN apoptotic signaling pathway; extrinsic apoptotic signaling pathway via death domain receptors; retinal cell programmed cell death; PARTICIPATES IN extrinsic apoptotic pathway; FasL mediated signaling pathway; interleukin-12 signaling pathway; ASSOCIATED WITH Acute Liver Failure; autoimmune hepatitis; Experimental Pancreatitis, Acute ; FOUND IN cell surface; external side of plasma membrane; caveola (ortholog); INTERACTS WITH 1,2-dichloroethane; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: APT1LG1; CD178; CD95 ligand; CD95-L; CD95L; Fas antigen ligand; Fas-L; Fas-Ligand; Faslg; generalized lymphoproliferative disease; gld; Tnfsf6; Tnlg1a; tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand 1a; tumor necrosis factor ligand superfamily member 6
Homo sapiens (human) : FASLG (Fas ligand)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Faslg (Fas ligand)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Faslg (Fas ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : FASLG (Fas ligand)
Canis lupus familiaris (dog) : FASLG (Fas ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Faslg (Fas ligand)
Sus scrofa (pig) : FASLG (Fas ligand (TNF superfamily, member 6))
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381161,780,691 - 161,788,495 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371163,710,820 - 163,718,626 (-)NCBIGRCm37mm9NCBIm37
MGSCv361163,617,366 - 163,625,172 (-)NCBImm8
Celera1164,235,657 - 164,243,458 (-)NCBICelera
Cytogenetic Map1 H2.1NCBI
cM Map169.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fasl
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553064
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.