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Gene: Cycs (cytochrome c, somatic) Mus musculus
Symbol: Cycs
Name: cytochrome c, somatic
Description: Exhibits heme binding activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; hydrogen peroxide metabolic process; and regulation of protein binding activity. Localizes to cytosol and mitochondrion. Is expressed in several structures, including central nervous system; jaw; limb; metanephros; and spiral ligament. Human ortholog(s) of this gene implicated in cholangiocarcinoma; lung non-small cell carcinoma; pancreatic cancer; and thrombocytopenia. Orthologous to human CYCS (cytochrome c, somatic); PARTICIPATES IN cardiolipin metabolic pathway; ceramide signaling pathway; electron transport chain pathway; INTERACTS WITH (+)-dexrazoxane; (-)-citrinin; (-)-selegiline.
Type: protein-coding
RefSeq Status: VALIDATED
Homo sapiens (human) : CYCS (cytochrome c, somatic)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cycs (cytochrome c, somatic)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102023786 (cytochrome c, somatic)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986481 (cytochrome c)
Canis lupus familiaris (dog) : CYCS (cytochrome c, somatic)
Sus scrofa (pig) : CYCS (cytochrome c, somatic)
Heterocephalus glaber (naked mole-rat) : LOC101718508 (cytochrome c, somatic)
more info ...
Related Pseudogenes: Cycs-ps1   Cycs-ps2   Cycs-ps3   Gm10053   Gm10108   Gm10121   Gm19880   Gm19932   Gm48758  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl650,562,563 - 50,566,538 (-)EnsemblGRCm38mm10GRCm38
GRCm38650,562,563 - 50,566,569 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37650,512,562 - 50,516,473 (-)NCBIGRCm37mm9NCBIm37
MGSCv36650,492,149 - 50,496,060 (-)NCBImm8
Celera651,079,647 - 51,083,558 (-)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map624.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cycs
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10425
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.