Ddit4 (DNA-damage-inducible transcript 4) - Rat Genome Database

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Gene: Ddit4 (DNA-damage-inducible transcript 4) Mus musculus
Analyze
Symbol: Ddit4
Name: DNA-damage-inducible transcript 4
RGD ID: 733067
MGI Page MGI
Description: Enables 14-3-3 protein binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Acts upstream of or within several processes, including cellular response to dexamethasone stimulus; negative regulation of TOR signaling; and negative regulation of glycolytic process. Located in mitochondrion. Is expressed in several structures, including reproductive system and retina nuclear layer. Orthologous to human DDIT4 (DNA damage inducible transcript 4).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 5830413E08Rik; AA415483; dexamethasone-induced gene 2 protein; Dig; dig2; DNA damage-inducible transcript 4 protein; DNA-damage-inducible transcript 4 protein; HIF-1 responsive protein RTP801; HIF-1 responsive RTP801; protein regulated in development and DNA damage response 1; REDD; REDD-1; REDD1; Rtp8; Rtp801
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391059,785,497 - 59,787,592 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1059,785,491 - 59,787,656 (-)EnsemblGRCm39 Ensembl
GRCm381059,949,675 - 59,951,770 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1059,949,669 - 59,951,834 (-)EnsemblGRCm38mm10GRCm38
MGSCv371059,412,423 - 59,414,518 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361059,345,032 - 59,347,127 (-)NCBIMGSCv36mm8
Celera1061,046,891 - 61,048,986 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1029.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(1->4)-beta-D-glucan  (EXP)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,3-dinitrobenzene  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
7,12-dimethyltetraphene  (EXP)
acetamide  (ISO)
acrylamide  (EXP,ISO)
adenine  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
AM-251  (ISO)
amino acid  (EXP)
amiodarone  (ISO)
ammonium chloride  (ISO)
anthracen-2-amine  (ISO)
antimycin A  (ISO)
arachidonic acid  (ISO)
arecoline  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
atrazine  (ISO)
Azaspiracid  (ISO)
bafilomycin A1  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A5  (ISO)
butyric acid  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (EXP,ISO)
carbon nanotube  (EXP)
carvedilol  (EXP)
cefaloridine  (ISO)
celastrol  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (EXP)
cidofovir anhydrous  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
clodronic acid  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (EXP)
dieldrin  (ISO)
diethyl maleate  (ISO)
diethyldithiocarbamic acid  (ISO)
diethylstilbestrol  (EXP)
diisononyl phthalate  (EXP,ISO)
dimethylselenide  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP)
doxycycline  (EXP)
endosulfan  (ISO)
ethanol  (ISO)
Ethylenethiourea  (ISO)
etoposide  (ISO)
fenofibrate  (ISO)
ferric oxide  (EXP)
fluoranthene  (EXP)
flusilazole  (EXP)
folic acid  (EXP,ISO)
folpet  (EXP)
formaldehyde  (ISO)
gedunin  (ISO)
gemcitabine  (ISO)
genistein  (EXP)
glycidol  (ISO)
glyphosate  (EXP,ISO)
gold atom  (EXP)
gold(0)  (EXP)
GW 501516  (ISO)
helenalin  (ISO)
hexaconazole  (EXP)
hexanal  (ISO)
hydrogen cyanide  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxyl  (ISO)
ifosfamide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
irinotecan  (ISO)
iron dichloride  (ISO)
isobutanol  (ISO)
isoprenaline  (EXP)
kenpaullone  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
LY294002  (ISO)
mancozeb  (ISO)
maneb  (ISO)
menadione  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
microcystin-LR  (EXP)
mifepristone  (ISO)
mithramycin  (ISO)
mitomycin C  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
motexafin gadolinium  (ISO)
Muraglitazar  (ISO)
N(4)-hydroxycytidine  (EXP)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-succinylsulfathiazole  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
nicotine  (EXP,ISO)
nitrofen  (ISO)
ochratoxin A  (ISO)
orlistat  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
picene  (ISO)
pinostrobin  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP)
potassium cyanide  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propiconazole  (EXP)
prothioconazole  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
raloxifene  (ISO)
ranitidine  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
Salidroside  (ISO)
Salinomycin  (ISO)
SB 203580  (EXP)
SB 431542  (ISO)
SCH 23390  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sorafenib  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP,ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thifluzamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
triacsin C  (ISO)
triadimefon  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vanillin  (ISO)
vinclozolin  (ISO)
withaferin A  (ISO)
Yessotoxin  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Shoshani T, etal., Mol Cell Biol 2002 Apr;22(7):2283-93.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12453409   PMID:12477932   PMID:12520002   PMID:12736248   PMID:15226823   PMID:15452091   PMID:15545625   PMID:15632201  
PMID:15988001   PMID:16141072   PMID:16141073   PMID:17005863   PMID:17170753   PMID:17556672   PMID:18070882   PMID:18198340   PMID:18988856   PMID:19996311   PMID:20176937   PMID:20185832  
PMID:20354178   PMID:20473305   PMID:21267068   PMID:21368030   PMID:21383064   PMID:21733849   PMID:21873635   PMID:21896779   PMID:21909097   PMID:22797524   PMID:23000413   PMID:23024063  
PMID:23375831   PMID:23533084   PMID:24048858   PMID:24191950   PMID:24374096   PMID:24615339   PMID:24728411   PMID:24850856   PMID:24876363   PMID:25016184   PMID:25056877   PMID:25159324  
PMID:25315696   PMID:25445588   PMID:25504525   PMID:25548280   PMID:25716553   PMID:25916556   PMID:26296313   PMID:26301899   PMID:26487002   PMID:27189933   PMID:27465734   PMID:27556956  
PMID:27898044   PMID:27913296   PMID:27922594   PMID:28334504   PMID:28473584   PMID:28765650   PMID:28899858   PMID:29074598   PMID:29130486   PMID:29547704   PMID:29895328   PMID:29909290  
PMID:30372793   PMID:30538043   PMID:31142573   PMID:31241142   PMID:31638187   PMID:32032578   PMID:32043636   PMID:32064044   PMID:32273287   PMID:32295843   PMID:32732871   PMID:32768422  
PMID:32956680   PMID:33322202   PMID:33833132   PMID:33962393   PMID:33984337   PMID:34175899   PMID:34321999   PMID:34664403   PMID:34672766   PMID:34730176   PMID:34779712   PMID:35046889  
PMID:35984399   PMID:36170669   PMID:36272977   PMID:36309088   PMID:36383638   PMID:36444820   PMID:36528956   PMID:36883011   PMID:37016173   PMID:37039821   PMID:37392853  


Genomics

Comparative Map Data
Ddit4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391059,785,497 - 59,787,592 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1059,785,491 - 59,787,656 (-)EnsemblGRCm39 Ensembl
GRCm381059,949,675 - 59,951,770 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1059,949,669 - 59,951,834 (-)EnsemblGRCm38mm10GRCm38
MGSCv371059,412,423 - 59,414,518 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361059,345,032 - 59,347,127 (-)NCBIMGSCv36mm8
Celera1061,046,891 - 61,048,986 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1029.66NCBI
DDIT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381072,273,924 - 72,276,036 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1072,273,919 - 72,276,036 (+)EnsemblGRCh38hg38GRCh38
GRCh371074,033,682 - 74,035,794 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361073,703,683 - 73,705,803 (+)NCBINCBI36Build 36hg18NCBI36
Build 341073,703,682 - 73,705,803NCBI
Celera1067,317,429 - 67,319,550 (+)NCBICelera
Cytogenetic Map10q22.1ENTREZGENE
HuRef1068,028,151 - 68,030,271 (+)NCBIHuRef
CHM1_11074,315,457 - 74,317,577 (+)NCBICHM1_1
T2T-CHM13v2.01073,144,950 - 73,147,062 (+)NCBIT2T-CHM13v2.0
Ddit4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82028,434,938 - 28,437,037 (-)NCBIGRCr8
mRatBN7.22027,891,989 - 27,894,088 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2027,891,998 - 27,894,105 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2028,903,584 - 28,905,683 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02028,289,842 - 28,291,941 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02029,032,605 - 29,034,704 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02029,509,283 - 29,511,382 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2029,509,289 - 29,511,382 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02031,315,024 - 31,317,123 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42027,252,273 - 27,254,371 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12027,266,073 - 27,268,171 (-)NCBI
Celera2029,333,162 - 29,335,357 (-)NCBICelera
Cytogenetic Map20q11NCBI
Ddit4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543719,322,407 - 19,324,562 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543719,322,407 - 19,324,562 (-)NCBIChiLan1.0ChiLan1.0
DDIT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2884,423,173 - 84,426,596 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11084,429,789 - 84,431,917 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01068,796,712 - 68,798,840 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11071,264,028 - 71,266,155 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1071,264,029 - 71,266,149 (+)Ensemblpanpan1.1panPan2
DDIT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1422,916,718 - 22,918,893 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl422,916,096 - 22,964,035 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha423,053,206 - 23,055,382 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0423,196,970 - 23,199,141 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl423,196,350 - 23,199,152 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1423,097,917 - 23,100,093 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0423,298,834 - 23,301,011 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0423,652,232 - 23,654,408 (+)NCBIUU_Cfam_GSD_1.0
Ddit4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721358,154,142 - 58,156,276 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365216,646,797 - 6,648,983 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365216,646,864 - 6,648,982 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDIT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1475,117,710 - 75,119,902 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11475,117,708 - 75,119,907 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DDIT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1959,033,058 - 59,035,157 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl959,032,755 - 59,035,241 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604819,668,791 - 19,670,901 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddit4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247546,091,809 - 6,094,525 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247546,091,914 - 6,094,035 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ddit4
80 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:439
Count of miRNA genes:312
Interacting mature miRNAs:364
Transcripts:ENSMUST00000020308
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
10045632Heal16_mwound healing/regeneration 16 (mouse)Not determined103097449964974630Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
27095920Pglq9_mpelvic girdle length QTL 9, 10 week (mouse)103377599670835830Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse
26884421Cvht5_mcranial vault height 5, 10 week (mouse)104557609669135830Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
1357558Bmch4_mbone mechanical trait 4 (mouse)Not determined103157713665577284Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
12904011Cfq11_mconditioned fear QTL 11 (mouse)105648015660940841Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105109149085091639Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
26884400Huml5_mhumerus length 5, 16 week (mouse)104627609669235830Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4672040382491121Mouse
1300898Cfid_mcystic fibrosis intestinal distress (mouse)Not determined102972040363720483Mouse
4141070Ltgq1_mliver triglyceride QTL 1 (mouse)Not determined4123732675237326Mouse
4141159Phl2_mprogressive hearing loss 2 (mouse)Not determined104797449970112651Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105109149085091639Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105149340082491121Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse

Markers in Region
RH124270  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381059,949,862 - 59,950,006UniSTSGRCm38
MGSCv371059,412,610 - 59,412,754UniSTSGRCm37
Celera1061,047,078 - 61,047,222UniSTS
Cytogenetic Map10B3UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000020308   ⟹   ENSMUSP00000020308
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1059,785,491 - 59,787,656 (-)Ensembl
GRCm38.p6 Ensembl1059,949,669 - 59,951,834 (-)Ensembl
RefSeq Acc Id: NM_029083   ⟹   NP_083359
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391059,785,497 - 59,787,592 (-)NCBI
GRCm381059,949,675 - 59,951,770 (-)ENTREZGENE
MGSCv371059,412,423 - 59,414,518 (-)RGD
Celera1061,046,891 - 61,048,986 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_083359   ⟸   NM_029083
- UniProtKB: Q9D3F7 (UniProtKB/Swiss-Prot),   B7ZNP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020308   ⟸   ENSMUST00000020308

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D3F7-F1-model_v2 AlphaFold Q9D3F7 1-229 view protein structure

Promoters
RGD ID:6819169
Promoter ID:MM_KWN:4220
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_029083
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361059,414,461 - 59,415,342 (-)MPROMDB
RGD ID:8672046
Promoter ID:EPDNEW_M14054
Type:single initiation site
Name:Ddit4_1
Description:Mus musculus DNA-damage-inducible transcript 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381059,951,833 - 59,951,893EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921997 AgrOrtholog
Ensembl Genes ENSMUSG00000020108 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020308 ENTREZGENE
  ENSMUST00000020308.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.470.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RTP801-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RTP801-like_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:74747 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1921997 ENTREZGENE
NCBI Gene 74747 ENTREZGENE
PANTHER DNA DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12478 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RTP801_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ddit4 PhenoGen
UniProt B7ZNP9 ENTREZGENE, UniProtKB/TrEMBL
  DDIT4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE