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Gene: Ddit4 (DNA-damage-inducible transcript 4) Mus musculus
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Symbol: Ddit4
Name: DNA-damage-inducible transcript 4
Description: ENCODES a protein that exhibits 14-3-3 protein binding; INVOLVED IN cellular response to dexamethasone stimulus; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of glycolytic process; PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH abnormal cell morphology; abnormal retinal vasculature morphology; decreased retinal apoptosis; ASSOCIATED WITH leukemia (ortholog); mouth disease (ortholog); Nerve Degeneration (ortholog); FOUND IN mitochondrion; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5830413E08Rik; AA415483; dexamethasone-induced gene 2 protein; dig2; DNA damage-inducible transcript 4 protein; DNA-damage-inducible transcript 4 protein; HIF-1 responsive protein RTP801; HIF-1 responsive RTP801; protein regulated in development and DNA damage response 1; REDD-1; REDD1; Rtp801
Orthologs:
Homo sapiens (human) : DDIT4 (DNA damage inducible transcript 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ddit4 (DNA-damage-inducible transcript 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddit4 (DNA damage inducible transcript 4)
Pan paniscus (bonobo/pygmy chimpanzee) : DDIT4 (DNA damage inducible transcript 4)
Canis lupus familiaris (dog) : DDIT4 (DNA damage inducible transcript 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddit4 (DNA damage inducible transcript 4)
Sus scrofa (pig) : DDIT4 (DNA damage inducible transcript 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381059,949,675 - 59,951,770 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371059,412,423 - 59,414,518 (-)NCBIGRCm37mm9NCBIm37
MGSCv361059,345,032 - 59,347,127 (-)NCBImm8
Celera1061,046,891 - 61,048,986 (-)NCBICelera
Cytogenetic Map10 B4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ddit4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733067
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.