Mir26a-1 (microRNA 26a-1) - Rat Genome Database
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Gene: Mir26a-1 (microRNA 26a-1) Mus musculus
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Symbol: Mir26a-1
Name: microRNA 26a-1
RGD ID: 1607668
MGI Page MGI
Description: Involved in several processes, including cellular response to mechanical stimulus; long-term synaptic potentiation; and negative regulation of macromolecule metabolic process. Localizes to RISC complex and extracellular exosome. Is expressed in several structures, including brain and lung. Orthologous to human MIR26A1 (microRNA 26a-1).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Mir; miR-26a; mir-26a-1; Mirn2; Mirn26a; Mirn26a-1
RGD Orthologs
Human
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,860,864 - 118,860,953 (+)NCBIGRCm39mm39
GRCm389119,031,796 - 119,031,885 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,031,796 - 119,031,885 (+)EnsemblGRCm38mm10GRCm38
MGSCv379118,940,914 - 118,941,003 (+)NCBIGRCm37mm9NCBIm37
Celera9119,499,693 - 119,499,782 (+)NCBICelera
Cytogenetic Map9F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12007417   PMID:15538371   PMID:15845075   PMID:16369549   PMID:16381832   PMID:16766679   PMID:17369397   PMID:17604727   PMID:18281287   PMID:18452032   PMID:18556655   PMID:18713946  
PMID:18762567   PMID:19524505   PMID:19559694   PMID:19701194   PMID:20215419   PMID:20413612   PMID:20739651   PMID:20857419   PMID:21037258   PMID:21267068   PMID:21718763   PMID:21822254  
PMID:21903578   PMID:22210897   PMID:22496754   PMID:22673513   PMID:23028144   PMID:23254997   PMID:23543060   PMID:24047927   PMID:24114270   PMID:24205035   PMID:24328779   PMID:24594795  
PMID:25329154   PMID:25362566   PMID:25395662   PMID:25518928   PMID:25728641   PMID:25766405   PMID:25801675   PMID:25808510   PMID:25858512   PMID:25865461   PMID:25907560   PMID:25959411  
PMID:25961460   PMID:26050992   PMID:26063197   PMID:26107166   PMID:26247736   PMID:26313916   PMID:26320674   PMID:26376347   PMID:26776318   PMID:26787543   PMID:26818545   PMID:27040676  
PMID:27377869   PMID:28174206   PMID:28558034   PMID:28622289   PMID:29191656   PMID:29436664   PMID:29515367   PMID:29952219   PMID:30024304   PMID:30703362   PMID:30718039   PMID:31210329  
PMID:31338931   PMID:31364731   PMID:31474996   PMID:31488578   PMID:31593640   PMID:31964775   PMID:32092075  


Genomics

Comparative Map Data
Mir26a-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,860,864 - 118,860,953 (+)NCBIGRCm39mm39
GRCm389119,031,796 - 119,031,885 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,031,796 - 119,031,885 (+)EnsemblGRCm38mm10GRCm38
MGSCv379118,940,914 - 118,941,003 (+)NCBIGRCm37mm9NCBIm37
Celera9119,499,693 - 119,499,782 (+)NCBICelera
Cytogenetic Map9F3NCBI
MIR26A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl337,969,404 - 37,969,480 (+)EnsemblGRCh38hg38GRCh38
GRCh38337,969,404 - 37,969,480 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37338,010,895 - 38,010,971 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36337,985,898 - 37,985,974 (+)NCBINCBI36hg18NCBI36
Celera337,945,267 - 37,945,343 (+)NCBI
Cytogenetic Map3p22.2NCBI
HuRef337,953,581 - 37,953,657 (+)NCBIHuRef
CHM1_1337,962,544 - 37,962,620 (+)NCBICHM1_1
Mir26a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08127,714,441 - 127,714,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8127,714,441 - 127,714,530 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08126,931,592 - 126,931,681 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8117,928,870 - 117,928,959 (+)NCBICelera
Cytogenetic Map8q32NCBI
MIR26A-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl237,747,064 - 7,747,140 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1237,747,073 - 7,747,133 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Ezh2mmu-miR-26a-5pMirtarbaseexternal_infoqRT-PCR//Western blot//Reporter assay;Western blotFunctional MTI18281287
Srcin1mmu-miR-26a-5pMirtarbaseexternal_infoSequencingFunctional MTI (Weak)19536157
Ezh2mmu-miR-26a-5pTarbaseexternal_infoReporter GenePOSITIVE
Ezh2mmu-miR-26a-5pTarbaseexternal_infoqPCRPOSITIVE
Ezh2mmu-miR-26a-5pTarbaseexternal_infoWesternblitPOSITIVE
Spred3mmu-miR-26a-5pTarbaseexternal_infoSequencingPOSITIVE
Il6mmu-miR-26a-5pOncomiRDBexternal_infoNANA23389848
Nanos2mmu-miR-26a-5pOncomiRDBexternal_infoNANA23338972
Bag4mmu-miR-26a-5pOncomiRDBexternal_infoNANA23190898
Ptenmmu-miR-26a-5pOncomiRDBexternal_infoNANA22885155
Gsk3bmmu-miR-26a-5pOncomiRDBexternal_infoNANA22484120
Cdk6mmu-miR-26a-5pOncomiRDBexternal_infoNANA22210897
Esr1mmu-miR-26a-5pOncomiRDBexternal_infoNANA21610700
Ezh2mmu-miR-26a-5pOncomiRDBexternal_infoNANA21368858
Ezh2mmu-miR-26a-5pOncomiRDBexternal_infoNANA21199804
Mtdhmmu-miR-26a-5pOncomiRDBexternal_infoNANA20952513
Ptenmmu-miR-26a-5pOncomiRDBexternal_infoNANA20080666
Ccnd2mmu-miR-26a-5pOncomiRDBexternal_infoNANA19524505
Ptenmmu-miR-26a-5pOncomiRDBexternal_infoNANA19487573
Ezh2mmu-miR-26a-5pOncomiRDBexternal_infoNANA18713946

Predicted Targets
Summary Value
Count of predictions:8908
Count of gene targets:4577
Count of transcripts:6871
Interacting mature miRNAs:mmu-miR-26a-1-3p
Prediction methods:Microtar, Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083579
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,031,796 - 119,031,885 (+)Ensembl
RefSeq Acc Id: NR_029742
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,860,864 - 118,860,953 (+)NCBI
GRCm389119,031,796 - 119,031,885 (+)ENTREZGENE
MGSCv379118,940,914 - 118,941,003 (+)RGD
Celera9119,499,693 - 119,499,782 (+)RGD
cM Map9 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676900 AgrOrtholog
Ensembl Genes ENSMUSG00000065513 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083579 ENTREZGENE
MGD MGI:2676900 ENTREZGENE
miRBase MI0000573 ENTREZGENE
NCBI Gene 387218 ENTREZGENE
PhenoGen Mir26a-1 PhenoGen
RNAcentral URS00000C0D3F RNACentral
  URS000019B0F7 RNACentral
  URS000075D9C9 RNACentral