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Gene: Tnfrsf1b (tumor necrosis factor receptor superfamily, member 1b) Mus musculus
Symbol: Tnfrsf1b
Name: tumor necrosis factor receptor superfamily, member 1b
Description: Exhibits tumor necrosis factor-activated receptor activity. Involved in several processes, including apoptotic signaling pathway; regulation of cytokine production involved in immune response; and semi-lunar valve development. Localizes to the membrane raft. Human ortholog(s) of this gene implicated in several diseases, including Legionnaires' disease; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; genitourinary system; and liver. Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; amyotrophic lateral sclerosis pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD120b; p75; p75 TNFR; p80 TNF-alpha receptor; TNF receptor beta chain; TNF-alphaR2; TNF-R-II; TNF-R2; TNF-R75; TNF-RII; TNFalpha-R2; TNFBR; Tnfr-1; TNFR-II; Tnfr2; TNFR80; TNFRII; tumor necrosis factor receptor 2; tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor type II
Homo sapiens (human) : TNFRSF1B (TNF receptor superfamily member 1B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfrsf1b (TNF receptor superfamily member 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfrsf1b (TNF receptor superfamily member 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFRSF1B (TNF receptor superfamily member 1B)
Canis lupus familiaris (dog) : TNFRSF1B (TNF receptor superfamily member 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfrsf1b (TNF receptor superfamily member 1B)
Sus scrofa (pig) : TNFRSF1B (TNF receptor superfamily member 1B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4145,213,463 - 145,246,870 (-)Ensembl
GRCm384145,212,368 - 145,246,870 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374144,802,271 - 144,836,773 (-)NCBIGRCm37mm9NCBIm37
MGSCv364144,479,055 - 144,513,557 (-)NCBImm8
Celera4146,801,795 - 146,837,140 (-)NCBICelera
Cytogenetic Map4 E1NCBI
cM Map478.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tnfrsf1b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731571
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.