Gpx4 (glutathione peroxidase 4) - Rat Genome Database
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Gene: Gpx4 (glutathione peroxidase 4) Mus musculus
Analyze
Symbol: Gpx4
Name: glutathione peroxidase 4
RGD ID: 736050
MGI Page MGI
Description: Is expressed in several structures, including alimentary system; embryo ectoderm; extraembryonic component; nervous system; and sensory organ. Orthologous to human GPX4 (glutathione peroxidase 4).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1700027O09Rik; GPx-4; GSHPx-4; MGC103187; MGC118087; mtPHG; mtPHGPx; PHG; PHGPx; phospholipid hydroperoxide glutathione peroxidase; phospholipid hydroperoxide glutathione peroxidase, mitochondrial; phospholipid hydroperoxide glutathione peroxidase, nuclear; sn; snGPx; sperm nuclei glutathione peroxidase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gpx4-ps1   Gpx4-ps2  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,883,000 - 79,892,273 (+)NCBIGRCm39mm39
GRCm39 Ensembl1079,883,000 - 79,892,273 (+)Ensembl
GRCm381080,047,166 - 80,056,439 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,047,166 - 80,056,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,516,255 - 79,519,184 (+)NCBIGRCm37mm9NCBIm37
MGSCv361079,456,617 - 79,459,567 (+)NCBImm8
Celera1081,068,319 - 81,071,248 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP)
12(S)-HPETE  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-dinitrophenol  (ISO)
2-deoxy-D-glucose  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
all-trans-retinoic acid  (EXP)
amiodarone  (ISO)
ammonium chloride  (ISO)
apocynin  (EXP)
arachidonic acid  (ISO)
Aroclor 1254  (EXP)
arsenic acid  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
artesunate  (EXP,ISO)
astemizole  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
busulfan  (EXP)
butan-1-ol  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
Calcimycin  (ISO)
camptothecin  (ISO)
capsaicin  (EXP)
captan  (EXP)
carbon monoxide  (EXP)
cerium trichloride  (ISO)
chloropicrin  (ISO)
chloroquine  (EXP)
chlorpyrifos  (ISO)
choline  (EXP)
chromium(6+)  (EXP)
clofibrate  (ISO)
clothianidin  (EXP)
cobalt dichloride  (ISO)
conjugated linoleic acid  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
CU-O LINKAGE  (EXP)
cumene hydroperoxide  (EXP)
cyclophosphamide  (ISO)
cypermethrin  (EXP)
cyproconazole  (EXP)
DDE  (ISO)
desferrioxamine B  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
dimethyl fumarate  (ISO)
diquat  (EXP,ISO)
disodium selenite  (ISO)
diuron  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (EXP,ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
ethylene glycol dimethacrylate  (ISO)
fenofibrate  (EXP)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
fructose  (ISO)
Gastrodin  (EXP)
gentamycin  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
hypochlorous acid  (EXP)
Iodine aqueous  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (ISO)
L-ethionine  (ISO)
L-glutamic acid  (EXP)
L-methionine  (EXP)
lead diacetate  (ISO)
limonene  (ISO)
lycopene  (ISO)
maneb  (EXP,ISO)
microcystin-LR  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
naphthalene  (EXP)
naphthalenes  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitrogen dioxide  (ISO)
Nonylphenol  (ISO)
ochratoxin A  (ISO)
omeprazole  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
PCB138  (EXP)
pentachlorophenol  (EXP)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenylhydrazine  (EXP)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidylcholine  (ISO)
pirinixic acid  (EXP,ISO)
propiconazole  (EXP)
Pyridostigmine bromide  (ISO)
pyrimethamine  (EXP)
quercetin  (EXP)
resveratrol  (EXP)
rotenone  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenium atom  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
stavudine  (ISO)
sulforaphane  (EXP,ISO)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
tetracycline  (EXP)
tetrahydropalmatine  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
Triptolide  (EXP)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal apoptosis  (IAGP)
abnormal cellular respiration  (IAGP)
abnormal embryo size  (IEA)
abnormal embryonic tissue morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal germ layer development  (IAGP)
abnormal heart morphology  (IEA)
abnormal hippocampus CA3 region morphology  (IAGP)
abnormal male germ cell morphology  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal photoreceptor connecting cilium morphology  (IAGP)
abnormal photoreceptor inner segment morphology  (IAGP)
abnormal photoreceptor outer segment morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal social/conspecific interaction  (IAGP)
abnormal somatosensory cortex morphology  (IAGP)
abnormal sperm head morphology  (IAGP)
abnormal sperm midpiece morphology  (IAGP)
abnormal sperm mitochondrial sheath morphology  (IAGP)
abnormal sperm motility  (IAGP)
abnormal sperm physiology  (IAGP)
abnormal sperm principal piece morphology  (IAGP)
asthenozoospermia  (IAGP)
astrocytosis  (IAGP)
ataxia  (IAGP)
cachexia  (IAGP)
convulsive seizures  (IAGP)
decreased body weight  (IAGP)
decreased embryo size  (IAGP)
decreased fertilization frequency  (IAGP)
decreased litter size  (IAGP)
decreased male germ cell number  (IAGP)
decreased mitochondrial DNA content  (IAGP)
decreased testis weight  (IAGP)
disorganized photoreceptor outer segment  (IAGP)
embryonic lethality between implantation and placentation, complete penetrance  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IAGP)
embryonic lethality prior to organogenesis  (IEA)
embryonic lethality prior to tooth bud stage  (IEA)
embryonic lethality, complete penetrance  (IAGP)
empty decidua capsularis  (IAGP)
failure to gastrulate  (IAGP)
hairpin sperm flagellum  (IAGP)
hydrometra  (IEA)
impaired fertilization  (IAGP)
increased hepatocyte apoptosis  (IAGP)
increased mortality induced by gamma-irradiation  (IAGP)
increased neuron apoptosis  (IAGP)
kinked sperm flagellum  (IAGP)
lethality, complete penetrance  (IAGP)
lethargy  (IAGP)
male infertility  (IAGP)
neurodegeneration  (IAGP)
no abnormal phenotype detected  (IAGP)
oligozoospermia  (IAGP)
oxidative stress  (IAGP)
postnatal lethality  (IAGP)
preweaning lethality, complete penetrance  (IEA)
reduced male fertility  (IAGP)
retinal degeneration  (IAGP)
retinal outer nuclear layer degeneration  (IAGP)
small testis  (IAGP)
thin retinal inner nuclear layer  (IAGP)
weight loss  (IAGP)
References

Additional References at PubMed
PMID:7671812   PMID:8889548   PMID:9370288   PMID:9792801   PMID:10100845   PMID:10341094   PMID:10349636   PMID:10464096   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11294903  
PMID:12152197   PMID:12427732   PMID:12477932   PMID:12745070   PMID:12865426   PMID:12888488   PMID:12904583   PMID:14572612   PMID:14575705   PMID:14610273   PMID:14681479   PMID:15226823  
PMID:15496407   PMID:15637642   PMID:15782199   PMID:15831471   PMID:15888450   PMID:15901730   PMID:16107710   PMID:16141072   PMID:16141073   PMID:16246897   PMID:16445905   PMID:16458079  
PMID:16684775   PMID:16751776   PMID:17395155   PMID:17503194   PMID:17540721   PMID:17895430   PMID:17967808   PMID:18206984   PMID:18593884   PMID:18614015   PMID:18680556   PMID:18762024  
PMID:18799693   PMID:18823256   PMID:19007875   PMID:19417079   PMID:19433132   PMID:19447173   PMID:19744930   PMID:19769463   PMID:19783653   PMID:19890015   PMID:20234819   PMID:20798033  
PMID:21267068   PMID:21402720   PMID:21618532   PMID:21717270   PMID:21873635   PMID:22207760   PMID:22326323   PMID:22401858   PMID:22719900   PMID:23364477   PMID:23408027   PMID:23695217  
PMID:23770613   PMID:24191733   PMID:24457600   PMID:24803591   PMID:24897344   PMID:25313597   PMID:25402683   PMID:25824823   PMID:25843658   PMID:25922076   PMID:26042203   PMID:26050606  
PMID:26083388   PMID:26400084   PMID:26463424   PMID:27262435   PMID:27317670   PMID:27634046   PMID:27689697   PMID:27710939   PMID:28212525   PMID:28378742   PMID:28627418   PMID:28802016  
PMID:29232557   PMID:29290465   PMID:29937272   PMID:30226473   PMID:30289974   PMID:30938680   PMID:32286299   PMID:32290105   PMID:32541831   PMID:32581705  


Genomics

Comparative Map Data
Gpx4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,883,000 - 79,892,273 (+)NCBIGRCm39mm39
GRCm39 Ensembl1079,883,000 - 79,892,273 (+)Ensembl
GRCm381080,047,166 - 80,056,439 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,047,166 - 80,056,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,516,255 - 79,519,184 (+)NCBIGRCm37mm9NCBIm37
MGSCv361079,456,617 - 79,459,567 (+)NCBImm8
Celera1081,068,319 - 81,071,248 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
GPX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl191,103,926 - 1,106,791 (+)EnsemblGRCh38hg38GRCh38
GRCh38191,103,994 - 1,106,779 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37191,103,993 - 1,106,778 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,054,936 - 1,057,787 (+)NCBINCBI36hg18NCBI36
Build 34191,054,965 - 1,057,778NCBI
Celera191,036,910 - 1,039,761 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef19877,428 - 880,271 (+)NCBIHuRef
CHM1_1191,103,518 - 1,106,381 (+)NCBICHM1_1
Gpx4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.279,650,186 - 9,652,982 (-)NCBI
Rnor_6.0 Ensembl712,516,352 - 12,519,154 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0712,516,357 - 12,519,154 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0712,686,460 - 12,689,257 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,162,521 - 11,165,318 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1711,162,520 - 11,165,318 (-)NCBI
Celera77,826,041 - 7,828,838 (-)NCBICelera
Cytogenetic Map7q11NCBI
Gpx4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,767,975 - 6,772,178 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,767,969 - 6,772,256 (-)NCBIChiLan1.0ChiLan1.0
GPX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1191,082,917 - 1,085,538 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01920,904 - 23,828 (-)NCBIMhudiblu_PPA_v0panPan3
GPX4
(Canis lupus familiaris - dog)
No map positions available.
Gpx4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936588506,101 - 508,469 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,320,464 - 77,323,886 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,321,568 - 77,323,931 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,673,720 - 77,676,083 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPX4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16873,867 - 876,225 (+)NCBI
Gpx4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248287,534,251 - 7,536,675 (-)NCBI

Position Markers
RH125284  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381080,056,791 - 80,056,874UniSTSGRCm38
MGSCv371079,519,536 - 79,519,619UniSTSGRCm37
Celera1081,071,600 - 81,071,683UniSTS
Cytogenetic Map10C1UniSTS
cM Map1043.0UniSTS
RH137289  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371045,595,399 - 45,595,585UniSTSGRCm37
MGSCv371780,453,653 - 80,453,839UniSTSGRCm37
Celera1784,370,787 - 84,370,973UniSTS
Celera1046,742,274 - 46,742,460UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map10C1UniSTS
cM Map1744.0UniSTS
cM Map1043.0UniSTS
Gpx4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10C1UniSTS
cM Map1043.0UniSTS
cM Map1043.0UniSTS
Gpx4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381045,875,321 - 45,876,041UniSTSGRCm38
Celera1046,742,002 - 46,742,722UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map10B2UniSTS
Gpx4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381080,053,558 - 80,054,598UniSTSGRCm38
Celera1081,068,367 - 81,069,407UniSTS
Cytogenetic Map10C1UniSTS
Gpx4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381080,055,012 - 80,056,409UniSTSGRCm38
GRCm381045,875,620 - 45,876,036UniSTSGRCm38
Celera1081,069,821 - 81,071,218UniSTS
Celera1046,742,301 - 46,742,717UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map10B2UniSTS
Gpx4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381080,054,075 - 80,054,598UniSTSGRCm38
Celera1081,068,884 - 81,069,407UniSTS
Cytogenetic Map10C1UniSTS
Gpx4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10C1UniSTS
Gpx4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10C1UniSTS
cM Map1043.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101023252187565233Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101282830784243920Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101282830784243920Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101282830784243920Mouse
1357893Lvrq4_mliver weight QTL 4 (mouse)Not determined101282830784243920Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1282830784243920Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1282830784243920Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1282830784243920Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1282830784243920Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101282830784243920Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102300000091200000Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1045000000116100000Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045600000120800000Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4684430782655287Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104950223383502378Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined105001240884012633Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined105001240884012633Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined105001240884012633Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined105001244384012618Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined105001244384012618Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105125566085255809Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105125566085255809Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105161730482655287Mouse
14746991Manh68_mmandible shape 68 (mouse)105244466786444667Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105868113592681262Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059500000122500000Mouse
13208560Wght9_mweight 9 (mouse)1060000000121000000Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1064100000116100000Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106565510499655287Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106565510499655287Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106565510499655287Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106701240892422811Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067500000111900000Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1068000000125000000Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073671039107671185Mouse
4142107Obrq12_mobesity resistance QTL 12 (mouse)Not determined7415138482655287Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1074151384125680038Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1074151384125680038Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075502706109502905Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75502706109502905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075502706109502905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078545406112545406Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1368
Count of miRNA genes:435
Interacting mature miRNAs:494
Transcripts:ENSMUST00000097227, ENSMUST00000105372, ENSMUST00000136081, ENSMUST00000144698, ENSMUST00000145703, ENSMUST00000154095, ENSMUST00000183037
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001037741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_110342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA510431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB030643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB030728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB072797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC161120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF044056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF045768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF045769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF274027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI839907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ012104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK006441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU961981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY238083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA466677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX733872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D87896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ561430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000097227   ⟹   ENSMUSP00000094863
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1080,054,037 - 80,056,439 (+)Ensembl
RefSeq Acc Id: ENSMUST00000105372   ⟹   ENSMUSP00000101011
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1080,053,488 - 80,056,439 (+)Ensembl
RefSeq Acc Id: ENSMUST00000136081
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1080,055,998 - 80,056,363 (+)Ensembl
RefSeq Acc Id: ENSMUST00000144698
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1080,047,166 - 80,056,439 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145703
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1080,054,035 - 80,055,107 (+)Ensembl
RefSeq Acc Id: ENSMUST00000154095
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1080,055,894 - 80,056,365 (+)Ensembl
RefSeq Acc Id: ENSMUST00000183037   ⟹   ENSMUSP00000138186
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1080,054,465 - 80,056,394 (+)Ensembl
RefSeq Acc Id: NM_001037741   ⟹   NP_001032830
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,889,845 - 79,892,273 (+)NCBI
GRCm381080,054,011 - 80,056,439 (+)NCBI
MGSCv371079,516,255 - 79,519,184 (+)RGD
Celera1081,061,975 - 81,071,248 (+)NCBI
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001367995   ⟹   NP_001354924
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,889,493 - 79,892,273 (+)NCBI
GRCm381080,053,659 - 80,056,439 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008162   ⟹   NP_032188
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,889,399 - 79,892,273 (+)NCBI
GRCm381080,053,565 - 80,056,439 (+)NCBI
MGSCv371079,516,255 - 79,519,184 (+)RGD
Celera1081,061,975 - 81,071,248 (+)NCBI
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_110342
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,883,000 - 79,892,273 (+)NCBI
GRCm381080,047,166 - 80,056,439 (+)NCBI
Celera1081,061,975 - 81,071,248 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032188   ⟸   NM_008162
- Peptide Label: isoform A precursor
- UniProtKB: O70325 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001032830   ⟸   NM_001037741
- Peptide Label: isoform B
- UniProtKB: O70325 (UniProtKB/Swiss-Prot),   Q76LV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001354924   ⟸   NM_001367995
- Peptide Label: isoform C
RefSeq Acc Id: ENSMUSP00000101011   ⟸   ENSMUST00000105372
RefSeq Acc Id: ENSMUSP00000138186   ⟸   ENSMUST00000183037
RefSeq Acc Id: ENSMUSP00000094863   ⟸   ENSMUST00000097227

Promoters
RGD ID:6819402
Promoter ID:MM_KWN:4819
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney
Transcripts:OTTMUST00000045864
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361079,509,501 - 79,510,122 (+)MPROMDB
RGD ID:6819400
Promoter ID:MM_KWN:4820
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000105372,   NM_001037741,   OTTMUST00000045764
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361079,515,291 - 79,516,797 (+)MPROMDB
RGD ID:6819401
Promoter ID:MM_KWN:4821
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000045765,   OTTMUST00000045766
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361079,517,996 - 79,518,772 (+)MPROMDB
RGD ID:8672618
Promoter ID:EPDNEW_M14331
Type:initiation region
Name:Gpx4_3
Description:Mus musculus glutathione peroxidase 4 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14332  EPDNEW_M14333  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381080,047,256 - 80,047,316EPDNEW
RGD ID:8672602
Promoter ID:EPDNEW_M14332
Type:initiation region
Name:Gpx4_2
Description:Mus musculus glutathione peroxidase 4 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14333  EPDNEW_M14331  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381080,053,565 - 80,053,625EPDNEW
RGD ID:8672604
Promoter ID:EPDNEW_M14333
Type:initiation region
Name:Gpx4_1
Description:Mus musculus glutathione peroxidase 4 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14332  EPDNEW_M14331  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381080,054,037 - 80,054,097EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104767 AgrOrtholog
Ensembl Genes ENSMUSG00000065948
  ENSMUSG00000075706 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000094863 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000101011 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000138186 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000097227 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000105372 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000144698 ENTREZGENE
  ENSMUST00000183037 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glutathione_peroxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPX_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPX_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:625249 UniProtKB/Swiss-Prot
MGD MGI:104767 ENTREZGENE
NCBI Gene 625249 ENTREZGENE
PANTHER PTHR11592 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GSHPx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gpx4 PhenoGen
PIRSF Glutathion_perox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GLUTPROXDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLUTATHIONE_PEROXID_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GPX4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TI34_MOUSE UniProtKB/TrEMBL
  Q3TIF2_MOUSE UniProtKB/TrEMBL
  Q5XJZ8_MOUSE UniProtKB/TrEMBL
  Q76LV0 ENTREZGENE, UniProtKB/TrEMBL
  S4R1E5_MOUSE UniProtKB/TrEMBL
UniProt Secondary O35560 UniProtKB/Swiss-Prot
  Q8K4U8 UniProtKB/Swiss-Prot
  Q91XR9 UniProtKB/Swiss-Prot
  Q9JK35 UniProtKB/Swiss-Prot