(R)-carnitine increases uptake ISO RGD:733281 6480464 SLC22A4 protein results in increased uptake of Carnitine CTD PMID:21256917 1,1-dichloroethene decreases expression EXP 6480464 vinylidene chloride results in decreased expression of SLC22A4 mRNA CTD PMID:26682919 1,2-dimethylhydrazine decreases expression EXP 6480464 1, 2-Dimethylhydrazine results in decreased expression of SLC22A4 mRNA CTD PMID:22206623 17beta-estradiol multiple interactions ISO RGD:733281 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of SLC22A4 mRNA, [Estradiol co-treated with TGFB1 protein] results in increased expression of SLC22A4 mRNA CTD PMID:19619570 , PMID:30165855 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of SLC22A4 mRNA CTD PMID:19484750 17beta-estradiol increases expression ISO RGD:733281 6480464 Estradiol results in increased expression of SLC22A4 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:733281 6480464 2-methyl-2H-pyrazole-3-carboxylic acid 2-methyl-4-o-tolylazophenylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SLC22A4 mRNA] more ... CTD PMID:19619570 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SLC22A4 mRNA CTD PMID:19933214 , PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:733281 6480464 Tetrachlorodibenzodioxin results in increased expression of SLC22A4 mRNA CTD PMID:19619570 more ... 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO RGD:733281 6480464 Verapamil inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 5-aza-2'-deoxycytidine increases expression ISO RGD:733281 6480464 Decitabine results in increased expression of SLC22A4 mRNA CTD PMID:28597291 6-propyl-2-thiouracil affects expression ISO RGD:621149 6480464 Propylthiouracil affects the expression of SLC22A4 mRNA CTD PMID:24780913 acetamide decreases expression ISO RGD:621149 6480464 acetamide results in decreased expression of SLC22A4 mRNA CTD PMID:31881176 acrylamide increases expression ISO RGD:621149 6480464 Acrylamide results in increased expression of SLC22A4 mRNA CTD PMID:28959563 aflatoxin B1 affects expression ISO RGD:733281 6480464 Aflatoxin B1 affects the expression of SLC22A4 protein CTD PMID:20106945 aflatoxin B1 increases expression ISO RGD:733281 6480464 Aflatoxin B1 results in increased expression of SLC22A4 mRNA CTD PMID:22100608 all-trans-retinoic acid increases expression ISO RGD:733281 6480464 Tretinoin results in increased expression of SLC22A4 mRNA CTD PMID:23830798 allopurinol multiple interactions EXP 6480464 Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA], Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein] CTD PMID:21909718 , PMID:22865646 ammonium chloride affects expression ISO RGD:621149 6480464 Ammonium Chloride affects the expression of SLC22A4 mRNA CTD PMID:16483693 angelicin decreases expression EXP 6480464 angelicin results in decreased expression of SLC22A4 mRNA CTD PMID:22173200 antirheumatic drug decreases expression ISO RGD:733281 6480464 Antirheumatic Agents results in decreased expression of SLC22A4 mRNA CTD PMID:24449571 atropine multiple interactions ISO RGD:733281 6480464 Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 benzo[a]pyrene increases expression ISO RGD:733281 6480464 Benzoapyrene results in increased expression of SLC22A4 mRNA CTD PMID:20106945 more ... bisphenol A affects expression ISO RGD:621149 6480464 bisphenol A affects the expression of SLC22A4 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:733281 6480464 bisphenol A results in increased expression of SLC22A4 mRNA CTD PMID:31715268 bisphenol A increases methylation ISO RGD:621149 6480464 bisphenol A results in increased methylation of SLC22A4 gene CTD PMID:28505145 C60 fullerene decreases expression ISO RGD:621149 6480464 fullerene C60 results in decreased expression of SLC22A4 mRNA CTD PMID:19167457 cadmium atom multiple interactions ISO RGD:733281 6480464 Dithioerythritol inhibits the reaction [Cadmium results in decreased activity of SLC22A4 protein] CTD PMID:25490951 cadmium atom decreases activity ISO RGD:733281 6480464 Cadmium results in decreased activity of SLC22A4 protein CTD PMID:25490951 carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25620056 carvedilol multiple interactions ISO RGD:733281 6480464 carvedilol inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of SLC22A4 mRNA CTD PMID:28472532 ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of SLC22A4 mRNA CTD PMID:18353800 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with RELB mutant form co-treated with TNF protein] results in decreased expression of SLC22A4 mRNA CTD PMID:23625948 cobalt dichloride increases expression ISO RGD:621149 6480464 cobaltous chloride results in increased expression of SLC22A4 mRNA CTD PMID:24386269 cycloheximide increases expression ISO RGD:733281 6480464 Cycloheximide results in increased expression of SLC22A4 mRNA CTD PMID:19684285 cycloheximide multiple interactions ISO RGD:733281 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC22A4 mRNA CTD PMID:19684285 cyclosporin A increases expression ISO RGD:733281 6480464 Cyclosporine results in increased expression of SLC22A4 mRNA CTD PMID:20106945 dexamethasone multiple interactions ISO RGD:621149 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of SLC22A4 mRNA] CTD PMID:20032058 dexamethasone increases expression ISO RGD:621149 6480464 Dexamethasone results in increased expression of SLC22A4 mRNA CTD PMID:20032058 dextran sulfate multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of SLC22A4 mRNA CTD PMID:29950665 diltiazem multiple interactions ISO RGD:733281 6480464 Diltiazem inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 dithioerythritol multiple interactions ISO RGD:733281 6480464 Dithioerythritol inhibits the reaction [Cadmium results in decreased activity of SLC22A4 protein] more ... CTD PMID:25490951 doxorubicin decreases expression ISO RGD:733281 6480464 Doxorubicin results in decreased expression of SLC22A4 mRNA CTD PMID:29803840 ethanol multiple interactions EXP 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of SLC22A4 mRNA CTD PMID:30517762 flecainide multiple interactions ISO RGD:733281 6480464 Flecainide inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of SLC22A4 mRNA CTD PMID:25629700 formaldehyde increases expression ISO RGD:733281 6480464 Formaldehyde results in increased expression of SLC22A4 mRNA CTD PMID:23649840 graphite affects expression ISO RGD:621149 6480464 Graphite affects the expression of SLC22A4 mRNA CTD PMID:29933104 hydroxyurea increases uptake ISO RGD:733281 6480464 SLC22A4 protein results in increased uptake of Hydroxyurea CTD PMID:21256917 imperatorin decreases expression EXP 6480464 imperatorin results in decreased expression of SLC22A4 mRNA CTD PMID:22173200 ipratropium multiple interactions ISO RGD:733281 6480464 Ipratropium inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 L-cysteine multiple interactions ISO RGD:733281 6480464 Cysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein], Cysteine inhibits the reaction [methylmercuric chloride results in decreased activity of SLC22A4 protein] CTD PMID:25490951 leflunomide increases expression ISO RGD:621149 6480464 leflunomide results in increased expression of SLC22A4 mRNA CTD PMID:24136188 leflunomide decreases expression ISO RGD:733281 6480464 leflunomide results in decreased expression of SLC22A4 mRNA CTD PMID:28988120 lidocaine multiple interactions ISO RGD:733281 6480464 Lidocaine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 mangiferin increases expression EXP 6480464 mangiferin results in increased expression of SLC22A4 mRNA CTD PMID:21348301 mercury atom multiple interactions ISO RGD:733281 6480464 Acetylcysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein] more ... CTD PMID:25490951 mercury(0) multiple interactions ISO RGD:733281 6480464 Acetylcysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein] more ... CTD PMID:25490951 metformin decreases expression ISO RGD:621149 6480464 Metformin results in decreased expression of SLC22A4 mRNA CTD PMID:31324951 methapyrilene decreases expression ISO RGD:621149 6480464 Methapyrilene results in decreased expression of SLC22A4 mRNA CTD PMID:30467583 methyl methacrylate increases expression EXP 6480464 Methylmethacrylate results in increased expression of SLC22A4 mRNA CTD PMID:16916219 methylmercury chloride multiple interactions ISO RGD:733281 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased activity of SLC22A4 protein] more ... CTD PMID:25490951 N-acetyl-L-cysteine multiple interactions ISO RGD:733281 6480464 Acetylcysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein], Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased activity of SLC22A4 protein] CTD PMID:25490951 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of SLC22A4 mRNA CTD PMID:17942915 N-nitrosodiethylamine multiple interactions EXP 6480464 MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC22A4 mRNA] CTD PMID:17942915 nifedipine multiple interactions ISO RGD:733281 6480464 Nifedipine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 oxaliplatin multiple interactions ISO RGD:621149 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of SLC22A4 mRNA CTD PMID:25729387 oxaliplatin decreases expression ISO RGD:621149 6480464 oxaliplatin results in decreased expression of SLC22A4 mRNA CTD PMID:25729387 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of SLC22A4 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:733281 6480464 Acetaminophen results in increased expression of SLC22A4 mRNA CTD PMID:29067470 paracetamol decreases expression ISO RGD:733281 6480464 Acetaminophen results in decreased expression of SLC22A4 mRNA CTD PMID:26690555 phenformin increases response to substance EXP 6480464 SLC22A4 protein results in increased susceptibility to Phenformin CTD PMID:23221006 phenformin affects uptake EXP 6480464 SLC22A4 protein affects the uptake of Phenformin CTD PMID:23221006 pirinixic acid multiple interactions ISO RGD:733281 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC22A4 mRNA CTD PMID:19710929 Potassium 2,6-dihydroxytriazinecarboxylate multiple interactions EXP 6480464 Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA] more ... CTD PMID:21909718 more ... Potassium 2,6-dihydroxytriazinecarboxylate decreases expression EXP 6480464 potassium oxonate results in decreased expression of SLC22A4 mRNA, potassium oxonate results in decreased expression of SLC22A4 protein CTD PMID:21909718 more ... probenecid multiple interactions EXP 6480464 Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA], Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein] CTD PMID:22865646 , PMID:22967667 propafenone multiple interactions ISO RGD:733281 6480464 Propafenone inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 propranolol multiple interactions ISO RGD:733281 6480464 Propranolol inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 psoralen decreases expression EXP 6480464 Ficusin results in decreased expression of SLC22A4 mRNA CTD PMID:22173200 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA], Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein] CTD PMID:21909718 rotenone increases expression ISO RGD:621149 6480464 Rotenone results in increased expression of SLC22A4 mRNA CTD PMID:28374803 serpentine asbestos increases expression ISO RGD:733281 6480464 Asbestos, Serpentine results in increased expression of SLC22A4 mRNA CTD PMID:24160326 silicon dioxide increases expression ISO RGD:733281 6480464 Silicon Dioxide analog results in increased expression of SLC22A4 mRNA CTD PMID:25895662 silver atom increases expression EXP 6480464 Silver results in increased expression of SLC22A4 mRNA CTD PMID:27131904 silver(0) increases expression EXP 6480464 Silver results in increased expression of SLC22A4 mRNA CTD PMID:27131904 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of SLC22A4 mRNA CTD PMID:31170414 sodium dodecyl sulfate increases expression ISO RGD:733281 6480464 Sodium Dodecyl Sulfate results in increased expression of SLC22A4 mRNA CTD PMID:31734321 Soman increases expression ISO RGD:621149 6480464 Soman results in increased expression of SLC22A4 mRNA CTD PMID:19281266 spironolactone multiple interactions ISO RGD:733281 6480464 Spironolactone inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SLC22A4 mRNA CTD PMID:21641980 testosterone multiple interactions ISO RGD:621149 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of SLC22A4 mRNA] CTD PMID:20032058 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of SLC22A4 mRNA CTD PMID:17484886 tetrachloromethane multiple interactions EXP 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of SLC22A4 mRNA CTD PMID:30517762 tetraethylammonium multiple interactions ISO RGD:733281 6480464 Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] more ... CTD PMID:21641380 tetraethylammonium increases uptake ISO RGD:733281 6480464 SLC22A4 protein results in increased uptake of Tetraethylammonium CTD PMID:27504015 tetraethylammonium increases transport ISO RGD:733281 6480464 SLC22A4 protein results in increased transport of Tetraethylammonium CTD PMID:25490951 thimerosal decreases activity ISO RGD:733281 6480464 Thimerosal results in decreased activity of SLC22A4 protein CTD PMID:25490951 thioacetamide decreases expression ISO RGD:621149 6480464 Thioacetamide results in decreased expression of SLC22A4 mRNA CTD PMID:23411599 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of SLC22A4 mRNA CTD PMID:23557971 titanium dioxide multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of SLC22A4 mRNA CTD PMID:29950665 topotecan decreases expression ISO RGD:621149 6480464 Topotecan results in decreased expression of SLC22A4 mRNA CTD PMID:25729387 topotecan multiple interactions ISO RGD:621149 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of SLC22A4 mRNA CTD PMID:25729387 trans-piceid multiple interactions EXP 6480464 polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein] CTD PMID:22865646 trimellitic anhydride decreases expression EXP 6480464 trimellitic anhydride results in decreased expression of SLC22A4 mRNA CTD PMID:19042947 troglitazone increases expression ISO RGD:733281 6480464 troglitazone results in increased expression of SLC22A4 mRNA CTD PMID:19140230 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO RGD:733281 6480464 Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 valproic acid increases expression ISO RGD:733281 6480464 Valproic Acid results in increased expression of SLC22A4 mRNA CTD PMID:23179753 , PMID:29154799 valproic acid decreases expression ISO RGD:621149 6480464 Valproic Acid results in decreased expression of SLC22A4 mRNA CTD PMID:32437819 vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of SLC22A4 mRNA CTD PMID:18930951 verapamil multiple interactions ISO RGD:733281 6480464 Verapamil inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 zidovudine increases expression ISO RGD:733281 6480464 Zidovudine results in increased expression of SLC22A4 mRNA CTD PMID:24292225 zoledronic acid increases expression ISO RGD:733281 6480464 zoledronic acid results in increased expression of SLC22A4 mRNA CTD PMID:24714768
