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Gene: Bad (BCL2-associated agonist of cell death) Mus musculus
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Symbol: Bad
Name: BCL2-associated agonist of cell death
Description: Exhibits cysteine-type endopeptidase activator activity involved in apoptotic process; protein heterodimerization activity; and protein phosphatase binding activity. Involved in several processes, including apoptotic signaling pathway; positive regulation of cell differentiation; and regulation of apoptotic process. Localizes to the cytosol and mitochondrion. Human ortholog(s) of this gene implicated in endometrial cancer; lung non-small cell carcinoma; and pancreatic cancer. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human BAD (BCL2 associated agonist of cell death); PARTICIPATES IN adenosine signaling pathway; ceramide signaling pathway; endometrial cancer pathway; INTERACTS WITH 1,3-Dinitropyrene; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-nitropyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI325008; Bbc2; bcl-2-binding component 6; Bcl-associated death promoter; bcl-xL/Bcl-2-associated death promoter; bcl2 antagonist of cell death
Orthologs:
Homo sapiens (human) : BAD (BCL2 associated agonist of cell death)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bad (BCL2-associated agonist of cell death)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bad (BCL2 associated agonist of cell death)
Pan paniscus (bonobo/pygmy chimpanzee) : BAD (BCL2 associated agonist of cell death)
Canis lupus familiaris (dog) : BAD (BCL2 associated agonist of cell death)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bad (BCL2 associated agonist of cell death)
Sus scrofa (pig) : BAD (BCL2 associated agonist of cell death)
Chlorocebus sabaeus (green monkey) : BAD (BCL2 associated agonist of cell death)
Heterocephalus glaber (naked mole-rat) : Bad (BCL2 associated agonist of cell death)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl196,941,861 - 6,951,899 (+)Ensembl
GRCm38196,941,861 - 6,951,905 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37197,016,345 - 7,026,383 (+)NCBIGRCm37mm9NCBIm37
MGSCv36197,008,899 - 7,018,937 (+)NCBImm8
Celera196,718,952 - 6,728,909 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Bad
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733062
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.