(+)-pilocarpine multiple interactions EXP 6480464 Pilocarpine promotes the reaction [EIF2AK2 protein modified form results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:16492139 (+)-pilocarpine increases phosphorylation EXP 6480464 Pilocarpine results in increased phosphorylation of EIF2S1 protein CTD PMID:15003282 (+)-schisandrin B multiple interactions ISO RGD:620963 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of EIF2S1 mRNA] CTD PMID:31150632 (R)-lipoic acid multiple interactions ISO RGD:620963 6480464 Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of EIF2S1 protein modified form] CTD PMID:30605698 (S)-nicotine increases phosphorylation ISO RGD:620963 6480464 Nicotine results in increased phosphorylation of EIF2S1 protein CTD PMID:26803847 1,2-dichloroethane decreases expression EXP 6480464 ethylene dichloride results in decreased expression of EIF2S1 mRNA CTD PMID:28189721 , PMID:28960355 1,2-dimethylhydrazine decreases phosphorylation ISO RGD:620963 6480464 1, 2-Dimethylhydrazine results in decreased phosphorylation of EIF2S1 protein CTD PMID:29879413 1,2-dimethylhydrazine multiple interactions ISO RGD:620963 6480464 [1 more ... CTD PMID:29879413 1,4-dithiothreitol multiple interactions EXP 6480464 EIF2S1 protein mutant form inhibits the reaction [Dithiothreitol results in increased phosphorylation of EIF2S1 protein] CTD PMID:30385349 1,4-dithiothreitol increases phosphorylation EXP 6480464 Dithiothreitol results in increased phosphorylation of EIF2S1 protein CTD PMID:30385349 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of EIF2S1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EIF2S1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of EIF2S1 mRNA CTD PMID:17942748 17beta-estradiol increases expression ISO RGD:735608 6480464 Estradiol results in increased expression of EIF2S1 mRNA CTD PMID:16514628 17beta-estradiol multiple interactions ISO RGD:735608 6480464 Estradiol promotes the reaction [EIF2S1 protein binds to ESR1 protein] CTD PMID:27156127 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of EIF2S1 mRNA CTD PMID:15598610 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 2,2',4,4'-Tetrabromodiphenyl ether affects expression EXP 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether increases phosphorylation EXP 6480464 2 more ... CTD PMID:25639565 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735608 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of EIF2S1 mRNA CTD PMID:19684285 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:620963 6480464 EIF2S1 mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of HSPA5 protein] more ... CTD PMID:24932542 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:620963 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of EIF2S1 protein CTD PMID:24932542 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of EIF2S1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EIF2S1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735608 6480464 Tetrachlorodibenzodioxin results in increased expression of EIF2S1 mRNA CTD PMID:19684285 2,3-dimethoxynaphthalene-1,4-dione increases phosphorylation ISO RGD:735608 6480464 2 more ... CTD PMID:21703327 2,4-dichlorophenol increases phosphorylation ISO RGD:735608 6480464 2, 4-dichlorophenol results in increased phosphorylation of EIF2S1 protein CTD PMID:27853103 2,4-dichlorophenol multiple interactions EXP 6480464 Enzyme Inhibitors promotes the reaction [2, 4-dichlorophenol results in increased expression of EIF2S1 protein modified form] CTD PMID:25160872 2,4-dichlorophenol increases expression EXP 6480464 2, 4-dichlorophenol results in increased expression of EIF2S1 protein modified form CTD PMID:25160872 2,4-dinitrotoluene affects expression ISO RGD:620963 6480464 2, 4-dinitrotoluene affects the expression of EIF2S1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression ISO RGD:620963 6480464 2, 6-dinitrotoluene affects the expression of EIF2S1 mRNA CTD PMID:21346803 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO RGD:620963 6480464 4-phenylbutyric acid affects the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased phosphorylation of EIF2S1 protein] more ... CTD PMID:28844859 2-amino-2-deoxy-D-glucopyranose increases phosphorylation ISO RGD:735608 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:19383982 2-amino-2-deoxy-D-glucopyranose increases phosphorylation EXP 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose increases phosphorylation ISO RGD:620963 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:16324875 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:620963 6480464 EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:16324875 2-arachidonoylglycerol multiple interactions ISO RGD:735608 6480464 GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein], iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein] CTD PMID:32357311 2-arachidonoylglycerol increases phosphorylation ISO RGD:735608 6480464 glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein CTD PMID:32357311 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of EIF2S1 mRNA CTD PMID:18648102 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions EXP 6480464 4 more ... CTD PMID:27638049 4-amino-2,6-dinitrotoluene affects expression ISO RGD:620963 6480464 4-amino-2, 6-dinitrotoluene affects the expression of EIF2S1 mRNA CTD PMID:21346803 4-hydroxynon-2-enal multiple interactions ISO RGD:620963 6480464 Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of EIF2S1 protein] CTD PMID:24291486 4-hydroxynon-2-enal increases phosphorylation ISO RGD:620963 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of EIF2S1 protein CTD PMID:24291486 4-hydroxyphenyl retinamide increases phosphorylation ISO RGD:735608 6480464 Fenretinide results in increased phosphorylation of EIF2S1 protein CTD PMID:20022965 4-hydroxyphenyl retinamide multiple interactions ISO RGD:735608 6480464 EIF2AK3 mutant form inhibits the reaction [Fenretinide results in increased phosphorylation of EIF2S1 protein] CTD PMID:20022965 4-phenylbutyric acid multiple interactions ISO RGD:735608 6480464 4-phenylbutyric acid inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein], 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2S1 protein] CTD PMID:20876807 , PMID:28063906 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [anandamide results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:26513129 more ... 4-phenylbutyric acid multiple interactions ISO RGD:620963 6480464 4-phenylbutyric acid affects the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased phosphorylation of EIF2S1 protein] more ... CTD PMID:27484784 more ... 4-phenylbutyric acid decreases expression ISO RGD:620963 6480464 4-phenylbutyric acid results in decreased expression of EIF2S1 protein modified form CTD PMID:27484784 5-fluorouracil increases phosphorylation ISO RGD:735608 6480464 Fluorouracil results in increased phosphorylation of EIF2S1 protein CTD PMID:29879413 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide increases phosphorylation ISO RGD:620963 6480464 6-chloro-2 more ... CTD PMID:29653943 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:620963 6480464 4-phenylbutyric acid inhibits the reaction [6-chloro-2 more ... CTD PMID:29653943 acrolein increases phosphorylation ISO RGD:735608 6480464 Acrolein results in increased phosphorylation of EIF2S1 protein CTD PMID:18951912 acrylamide increases expression ISO RGD:620963 6480464 Acrylamide results in increased expression of EIF2S1 mRNA CTD PMID:15749267 acrylamide multiple interactions ISO RGD:735608 6480464 Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of EIF2S1 protein] CTD PMID:27634458 acrylamide increases phosphorylation ISO RGD:735608 6480464 Acrylamide results in increased phosphorylation of EIF2S1 protein CTD PMID:27634458 afimoxifene decreases expression ISO RGD:735608 6480464 afimoxifene results in decreased expression of EIF2S1 mRNA CTD PMID:16514628 aflatoxin B1 increases expression ISO RGD:735608 6480464 Aflatoxin B1 results in increased expression of EIF2S1 mRNA CTD PMID:22100608 aflatoxin B1 decreases methylation ISO RGD:735608 6480464 Aflatoxin B1 results in decreased methylation of EIF2S1 gene CTD PMID:27153756 AICA ribonucleotide decreases phosphorylation ISO RGD:735608 6480464 AICA ribonucleotide results in decreased phosphorylation of EIF2S1 protein CTD PMID:22898769 aldehydo-D-glucosamine increases phosphorylation ISO RGD:735608 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:19383982 aldehydo-D-glucosamine multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:30602124 aldehydo-D-glucosamine increases phosphorylation EXP 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:30602124 aldehydo-D-glucosamine increases phosphorylation ISO RGD:620963 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:16324875 aldehydo-D-glucosamine multiple interactions ISO RGD:620963 6480464 EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:16324875 aldehydo-D-glucose multiple interactions EXP 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Glucose results in increased phosphorylation of EIF2S1 protein] CTD PMID:18973755 aldehydo-D-glucose increases phosphorylation ISO RGD:735608 6480464 Glucose deficiency results in increased phosphorylation of EIF2S1 protein CTD PMID:31022492 aldehydo-D-glucose multiple interactions ISO RGD:735608 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein], salubrinal inhibits the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein]] CTD PMID:31022492 aldehydo-D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of EIF2S1 protein CTD PMID:18973755 all-trans-retinoic acid decreases expression ISO RGD:735608 6480464 Tretinoin results in decreased expression of EIF2S1 mRNA CTD PMID:16054129 all-trans-retinoic acid increases phosphorylation EXP 6480464 Tretinoin results in increased phosphorylation of EIF2S1 protein CTD PMID:22498432 all-trans-retinoic acid increases expression ISO RGD:620963 6480464 Tretinoin results in increased expression of EIF2S1 mRNA CTD PMID:24977338 Aloe emodin increases phosphorylation ISO RGD:735608 6480464 aloe emodin results in increased phosphorylation of EIF2S1 protein CTD PMID:22210228 alpha-naphthoflavone increases phosphorylation EXP 6480464 alpha-naphthoflavone results in increased phosphorylation of EIF2S1 protein CTD PMID:30508555 amino acid multiple interactions EXP 6480464 EIF2AK4 gene mutant form inhibits the reaction [Amino Acids deficiency results in increased phosphorylation of EIF2S1 protein], EIF2S1 protein mutant form inhibits the reaction [Amino Acids deficiency results in increased expression of DDIT3 protein] CTD PMID:16330322 , PMID:29449374 amino acid increases phosphorylation EXP 6480464 Amino Acids deficiency results in increased phosphorylation of EIF2S1 protein CTD PMID:29449374 , PMID:30196486 amiodarone increases phosphorylation ISO RGD:735608 6480464 Amiodarone results in increased phosphorylation of EIF2S1 protein CTD PMID:32651653 ammonium chloride affects expression ISO RGD:620963 6480464 Ammonium Chloride affects the expression of EIF2S1 mRNA CTD PMID:16483693 anandamide increases phosphorylation EXP 6480464 anandamide results in increased phosphorylation of EIF2S1 protein CTD PMID:26513129 anandamide multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [anandamide results in increased phosphorylation of EIF2S1 protein] CTD PMID:26513129 aristolochic acid increases phosphorylation ISO RGD:735608 6480464 aristolochic acid I results in increased phosphorylation of EIF2S1 protein CTD PMID:22445861 arsenite(3-) multiple interactions ISO RGD:735608 6480464 [arsenite results in increased phosphorylation of EIF2S1 protein] which results in decreased expression of MCL1 protein CTD PMID:17553788 arsenite(3-) decreases phosphorylation EXP 6480464 arsenite results in decreased phosphorylation of EIF2S1 protein CTD PMID:29109149 arsenite(3-) increases phosphorylation ISO RGD:735608 6480464 arsenite results in increased phosphorylation of EIF2S1 protein CTD PMID:17553788 more ... arsenite(3-) increases phosphorylation EXP 6480464 arsenite results in increased phosphorylation of EIF2S1 protein CTD PMID:24315374 arsenite(3-) multiple interactions EXP 6480464 EIF2S1 protein modified form affects the reaction [arsenite results in increased expression of DDIT3 protein] more ... CTD PMID:24315374 , PMID:29109149 arsenite(3-) decreases response to substance EXP 6480464 EIF2S1 protein mutant form results in decreased susceptibility to arsenite CTD PMID:24315374 arsenous acid increases expression ISO RGD:735608 6480464 Arsenic Trioxide results in increased expression of EIF2S1 protein modified form CTD PMID:22922937 arsenous acid multiple interactions ISO RGD:735608 6480464 Arsenic Trioxide promotes the reaction [MSI1 protein binds to EIF2S1 protein modified form] more ... CTD PMID:22922937 , PMID:29486283 arsenous acid multiple interactions EXP 6480464 4 more ... CTD PMID:27638049 arsenous acid increases phosphorylation ISO RGD:735608 6480464 Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein CTD PMID:25258189 , PMID:29486283 arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein CTD PMID:27638049 atorvastatin calcium multiple interactions ISO RGD:735608 6480464 4-phenylbutyric acid inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein], EIF2AK3 mutant form inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein] CTD PMID:20876807 atorvastatin calcium increases phosphorylation ISO RGD:735608 6480464 Atorvastatin results in increased phosphorylation of EIF2S1 protein CTD PMID:20876807 Aurin increases phosphorylation ISO RGD:735608 6480464 aurin results in increased phosphorylation of EIF2S1 protein CTD PMID:25477506 benzo[a]pyrene increases phosphorylation EXP 6480464 Benzoapyrene results in increased phosphorylation of EIF2S1 protein CTD PMID:30385349 benzo[a]pyrene multiple interactions EXP 6480464 EIF2S1 protein mutant form inhibits the reaction [Benzoapyrene results in increased phosphorylation of EIF2S1 protein] CTD PMID:30385349 benzo[a]pyrene diol epoxide I increases expression ISO RGD:735608 6480464 7 more ... CTD PMID:19150397 benzo[a]pyrene diol epoxide I multiple interactions EXP 6480464 EIF2S1 protein mutant form inhibits the reaction [7 more ... CTD PMID:30385349 benzo[a]pyrene diol epoxide I increases phosphorylation EXP 6480464 7 more ... CTD PMID:30385349 beta-carotene multiple interactions EXP 6480464 [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA CTD PMID:24657404 beta-D-glucosamine increases phosphorylation ISO RGD:735608 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:19383982 beta-D-glucosamine increases phosphorylation EXP 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:30602124 beta-D-glucosamine multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:30602124 beta-D-glucosamine increases phosphorylation ISO RGD:620963 6480464 Glucosamine results in increased phosphorylation of EIF2S1 protein CTD PMID:16324875 beta-D-glucosamine multiple interactions ISO RGD:620963 6480464 EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:16324875 bilirubin IXalpha multiple interactions ISO RGD:735608 6480464 Bilirubin results in increased phosphorylation of and results in increased activity of EIF2S1 protein CTD PMID:20196124 bisphenol A increases expression ISO RGD:620963 6480464 bisphenol A results in increased expression of EIF2S1 mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:735608 6480464 bisphenol A results in decreased expression of EIF2S1 mRNA CTD PMID:29275510 boric acid increases phosphorylation ISO RGD:735608 6480464 boric acid results in increased phosphorylation of EIF2S1 protein CTD PMID:25425213 , PMID:27587023 boric acid increases phosphorylation EXP 6480464 boric acid results in increased phosphorylation of EIF2S1 protein CTD PMID:30196486 boric acid multiple interactions EXP 6480464 EIF2AK3 protein affects the reaction [boric acid results in increased phosphorylation of EIF2S1 protein] CTD PMID:30196486 bortezomib multiple interactions ISO RGD:735608 6480464 Bortezomib inhibits the reaction [Tunicamycin results in increased phosphorylation of EIF2S1 protein], EIF2AK3 mutant form inhibits the reaction [Bortezomib results in increased phosphorylation of EIF2S1 protein] CTD PMID:16357177 , PMID:20022965 bortezomib increases phosphorylation EXP 6480464 Bortezomib results in increased phosphorylation of EIF2S1 protein CTD PMID:21090173 bortezomib increases phosphorylation ISO RGD:735608 6480464 Bortezomib results in increased phosphorylation of EIF2S1 protein CTD PMID:16357177 , PMID:20022965 bupropion increases phosphorylation ISO RGD:735608 6480464 Bupropion results in increased phosphorylation of EIF2S1 protein CTD PMID:21354251 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of EIF2S1 protein modified form CTD PMID:21908765 cadmium dichloride decreases expression ISO RGD:620963 6480464 Cadmium Chloride results in decreased expression of EIF2S1 mRNA CTD PMID:21297351 cadmium dichloride increases phosphorylation ISO RGD:735608 6480464 Cadmium Chloride results in increased phosphorylation of EIF2S1 protein CTD PMID:20600546 , PMID:21809093 cadmium dichloride multiple interactions ISO RGD:735608 6480464 salubrinal promotes the reaction [Cadmium Chloride results in increased phosphorylation of EIF2S1 protein] CTD PMID:21809093 cadmium dichloride multiple interactions EXP 6480464 Phenylbutyrates inhibits the reaction [Cadmium Chloride results in increased expression of EIF2S1 protein modified form] CTD PMID:21908765 calcitriol decreases expression ISO RGD:735608 6480464 Calcitriol results in decreased expression of EIF2S1 mRNA CTD PMID:16847355 camptothecin multiple interactions ISO RGD:735608 6480464 EIF2S1 protein affects the reaction [Camptothecin results in increased expression of ATG7 protein] more ... CTD PMID:30266318 camptothecin multiple interactions ISO RGD:620963 6480464 [Camptothecin co-treated with GW 506033X] results in increased phosphorylation of EIF2S1 protein CTD PMID:19046382 camptothecin increases phosphorylation ISO RGD:735608 6480464 Camptothecin results in increased phosphorylation of EIF2S1 protein CTD PMID:30266318 capsaicin increases phosphorylation ISO RGD:735608 6480464 Capsaicin results in increased phosphorylation of EIF2S1 protein CTD PMID:19139269 carbamazepine affects expression ISO RGD:735608 6480464 Carbamazepine affects the expression of EIF2S1 mRNA CTD PMID:24752500 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 carboplatin affects phosphorylation ISO RGD:735608 6480464 Carboplatin affects the phosphorylation of EIF2S1 protein CTD PMID:29053414 chlorpyrifos increases phosphorylation ISO RGD:735608 6480464 Chlorpyrifos results in increased phosphorylation of EIF2S1 protein CTD PMID:27993609 cholesterol decreases abundance EXP 6480464 EIF2S1 protein modified form results in decreased abundance of Cholesterol CTD PMID:16330322 chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of EIF2S1 mRNA CTD PMID:28472532 chrysophanol multiple interactions ISO RGD:735608 6480464 Acetylcysteine inhibits the reaction [chrysophanic acid results in increased phosphorylation of EIF2S1 protein] CTD PMID:30300626 chrysophanol increases phosphorylation ISO RGD:735608 6480464 chrysophanic acid results in increased phosphorylation of EIF2S1 protein CTD PMID:30300626 cisplatin multiple interactions ISO RGD:735608 6480464 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one inhibits the reaction [Cisplatin results in increased phosphorylation of EIF2S1 protein] CTD PMID:26338418 cisplatin increases phosphorylation ISO RGD:735608 6480464 Cisplatin results in increased phosphorylation of EIF2S1 protein CTD PMID:26338418 cocaine increases phosphorylation ISO RGD:620963 6480464 Cocaine results in increased phosphorylation of EIF2S1 CTD PMID:18593214 copper atom multiple interactions ISO RGD:735608 6480464 [Chelating Agents binds to Copper] which results in increased expression of EIF2S1 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:735608 6480464 [Chelating Agents binds to Copper] which results in increased expression of EIF2S1 mRNA CTD PMID:30911355 coumestrol increases expression ISO RGD:735608 6480464 Coumestrol results in increased expression of EIF2S1 mRNA CTD PMID:19167446 cycloheximide increases expression ISO RGD:735608 6480464 Cycloheximide results in increased expression of EIF2S1 mRNA CTD PMID:19684285 cycloheximide increases phosphorylation EXP 6480464 Cycloheximide results in increased phosphorylation of EIF2S1 protein CTD PMID:24315374 cycloheximide multiple interactions ISO RGD:735608 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of EIF2S1 mRNA CTD PMID:19684285 cyclosporin A increases phosphorylation EXP 6480464 Cyclosporine results in increased phosphorylation of EIF2S1 protein CTD PMID:22155090 D-glucose multiple interactions EXP 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Glucose results in increased phosphorylation of EIF2S1 protein] CTD PMID:18973755 D-glucose multiple interactions ISO RGD:735608 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein], salubrinal inhibits the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein]] CTD PMID:31022492 D-glucose increases phosphorylation ISO RGD:735608 6480464 Glucose deficiency results in increased phosphorylation of EIF2S1 protein CTD PMID:31022492 D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of EIF2S1 protein CTD PMID:18973755 D-penicillamine increases phosphorylation ISO RGD:735608 6480464 Penicillamine results in increased phosphorylation of EIF2S1 protein CTD PMID:22843330 dantrolene decreases phosphorylation ISO RGD:620963 6480464 Dantrolene results in decreased phosphorylation of EIF2S1 protein CTD PMID:15921666 dantrolene multiple interactions ISO RGD:735608 6480464 Dantrolene inhibits the reaction [tributyltin results in increased phosphorylation of EIF2S1 protein] CTD PMID:23743301 diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein CTD PMID:27638049 diarsenic trioxide multiple interactions EXP 6480464 4 more ... CTD PMID:27638049 diarsenic trioxide multiple interactions ISO RGD:735608 6480464 Arsenic Trioxide promotes the reaction [MSI1 protein binds to EIF2S1 protein modified form] more ... CTD PMID:22922937 , PMID:29486283 diarsenic trioxide increases expression ISO RGD:735608 6480464 Arsenic Trioxide results in increased expression of EIF2S1 protein modified form CTD PMID:22922937 diarsenic trioxide increases phosphorylation ISO RGD:735608 6480464 Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein CTD PMID:25258189 , PMID:29486283 dibutyl phthalate decreases expression ISO RGD:620963 6480464 Dibutyl Phthalate results in decreased expression of EIF2S1 mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased expression of EIF2S1 protein modified form] CTD PMID:26804720 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of EIF2S1 protein modified form CTD PMID:26804720 dibutyl phthalate increases expression ISO RGD:620963 6480464 Dibutyl Phthalate results in increased expression of EIF2S1 mRNA CTD PMID:21266533 dichlorine multiple interactions ISO RGD:620963 6480464 [Ozone co-treated with Chlorine] results in decreased expression of EIF2S1 mRNA CTD PMID:18636392 diclofenac affects expression ISO RGD:735608 6480464 Diclofenac affects the expression of EIF2S1 mRNA CTD PMID:24752500 diclofenac multiple interactions ISO RGD:735608 6480464 [TNF protein co-treated with Diclofenac] results in increased phosphorylation of EIF2S1 protein CTD PMID:27313093 dihydrocapsaicin increases phosphorylation ISO RGD:735608 6480464 dihydrocapsaicin results in increased phosphorylation of EIF2S1 protein CTD PMID:19139269 dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of EIF2S1 mRNA CTD PMID:30529165 dorsomorphin increases phosphorylation ISO RGD:735608 6480464 dorsomorphin results in increased phosphorylation of EIF2S1 protein CTD PMID:22898769 dorsomorphin multiple interactions ISO RGD:735608 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of EIF2S1 mRNA CTD PMID:27188386 doxorubicin multiple interactions ISO RGD:735608 6480464 Doxorubicin promotes the reaction [MSI1 protein binds to EIF2S1 protein modified form] CTD PMID:29486283 ebselen increases phosphorylation ISO RGD:620963 6480464 ebselen results in increased phosphorylation of EIF2S1 protein CTD PMID:27282967 endosulfan increases expression ISO RGD:620963 6480464 Endosulfan results in increased expression of EIF2S1 mRNA CTD PMID:31464424 enzyme inhibitor increases expression EXP 6480464 Enzyme Inhibitors results in increased expression of EIF2S1 protein modified form CTD PMID:25160872 enzyme inhibitor multiple interactions EXP 6480464 Enzyme Inhibitors promotes the reaction [2, 4-dichlorophenol results in increased expression of EIF2S1 protein modified form] CTD PMID:25160872 epoxomicin multiple interactions EXP 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 erlotinib hydrochloride increases expression ISO RGD:620963 6480464 Erlotinib Hydrochloride results in increased expression of EIF2S1 protein modified form CTD PMID:24768708 ethanol multiple interactions ISO RGD:735608 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of EIF2S1 protein modified form] CTD PMID:24224909 ethanol increases expression ISO RGD:735608 6480464 Ethanol results in increased expression of EIF2S1 protein modified form CTD PMID:24224909 flavokawain B increases phosphorylation ISO RGD:735608 6480464 flavokawain B results in increased phosphorylation of EIF2S1 protein CTD PMID:30025493 flavonoids decreases expression ISO RGD:620963 6480464 Flavonoids results in decreased expression of EIF2S1 mRNA CTD PMID:18035473 flutamide increases expression ISO RGD:620963 6480464 Flutamide results in increased expression of EIF2S1 mRNA CTD PMID:24136188 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of EIF2S1 mRNA CTD PMID:25629700 fructose increases phosphorylation EXP 6480464 Fructose results in increased phosphorylation of EIF2S1 protein CTD PMID:22698815 fructose multiple interactions EXP 6480464 Phenylbutyrates inhibits the reaction [Fructose results in increased phosphorylation of EIF2S1 protein] CTD PMID:22698815 fulvestrant decreases expression ISO RGD:735608 6480464 fulvestrant results in decreased expression of EIF2S1 mRNA CTD PMID:16514628 gentamycin increases expression ISO RGD:620963 6480464 Gentamicins results in increased expression of EIF2S1 mRNA CTD PMID:22061828 geraniol multiple interactions ISO RGD:735608 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of EIF2S1 protein] CTD PMID:30141137 glafenine increases expression ISO RGD:620963 6480464 Glafenine results in increased expression of EIF2S1 mRNA CTD PMID:24136188 glucose multiple interactions EXP 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Glucose results in increased phosphorylation of EIF2S1 protein] CTD PMID:18973755 glucose multiple interactions ISO RGD:735608 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein], salubrinal inhibits the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein]] CTD PMID:31022492 glucose increases phosphorylation ISO RGD:735608 6480464 Glucose deficiency results in increased phosphorylation of EIF2S1 protein CTD PMID:31022492 glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of EIF2S1 protein CTD PMID:18973755 glutathione multiple interactions ISO RGD:735608 6480464 Glutathione inhibits the reaction [Camptothecin results in increased phosphorylation of EIF2S1 protein] CTD PMID:30266318 glyphosate decreases expression ISO RGD:620963 6480464 glyphosate results in decreased expression of EIF2S1 mRNA CTD PMID:26302742 GSK2656157 multiple interactions EXP 6480464 GSK2656157 inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:30602124 GSK2656157 multiple interactions ISO RGD:735608 6480464 GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein] CTD PMID:32357311 Guanabenz multiple interactions ISO RGD:620963 6480464 Guanabenz promotes the reaction [Tunicamycin results in increased phosphorylation of EIF2S1 protein] CTD PMID:24892553 Guanabenz multiple interactions EXP 6480464 Guanabenz inhibits the reaction [Acetaminophen results in decreased phosphorylation of EIF2S1 protein] CTD PMID:31524377 hexadecanoic acid multiple interactions EXP 6480464 7 more ... CTD PMID:29414781 , PMID:30208301 hexadecanoic acid increases phosphorylation EXP 6480464 Palmitic Acid results in increased phosphorylation of EIF2S1 protein CTD PMID:29414781 , PMID:30208301 homocysteic acid multiple interactions ISO RGD:620963 6480464 [homocysteic acid co-treated with GW 506033X] results in increased phosphorylation of EIF2S1 protein CTD PMID:19046382 homocysteine increases phosphorylation ISO RGD:735608 6480464 Homocysteine results in increased phosphorylation of EIF2S1 protein CTD PMID:22964297 hydrogen peroxide increases phosphorylation ISO RGD:620963 6480464 Hydrogen Peroxide results in increased phosphorylation of EIF2S1 protein CTD PMID:16324875 hydrogen peroxide multiple interactions ISO RGD:620963 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of EIF2S1 protein] CTD PMID:16324875 indoxyl sulfate increases phosphorylation EXP 6480464 Indican results in increased phosphorylation of EIF2S1 protein CTD PMID:29380555 indoxyl sulfate multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of EIF2S1 protein] CTD PMID:29380555 ketoconazole multiple interactions EXP 6480464 EIF2S1 protein mutant form inhibits the reaction [Ketoconazole results in increased expression of DDIT3 mRNA] more ... CTD PMID:16330322 L-1,4-dithiothreitol multiple interactions EXP 6480464 EIF2S1 protein mutant form inhibits the reaction [Dithiothreitol results in increased phosphorylation of EIF2S1 protein] CTD PMID:30385349 L-1,4-dithiothreitol increases phosphorylation EXP 6480464 Dithiothreitol results in increased phosphorylation of EIF2S1 protein CTD PMID:30385349 lead diacetate increases phosphorylation ISO RGD:620963 6480464 lead acetate results in increased phosphorylation of EIF2S1 protein CTD PMID:25088297 lead diacetate multiple interactions ISO RGD:620963 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of EIF2S1 protein] CTD PMID:25088297 lead(II) chloride increases phosphorylation ISO RGD:735608 6480464 lead chloride results in increased phosphorylation of EIF2S1 protein CTD PMID:25410796 leflunomide increases phosphorylation ISO RGD:735608 6480464 leflunomide results in increased phosphorylation of EIF2S1 protein CTD PMID:28988120 linsidomine increases phosphorylation ISO RGD:735608 6480464 linsidomine results in increased phosphorylation of EIF2S1 protein CTD PMID:21703327 lipoic acid multiple interactions ISO RGD:620963 6480464 Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of EIF2S1 protein modified form] CTD PMID:30605698 lipopolysaccharide multiple interactions ISO RGD:620963 6480464 4-phenylbutyric acid affects the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased phosphorylation of EIF2S1 protein] more ... CTD PMID:28844859 lipopolysaccharide increases phosphorylation ISO RGD:735608 6480464 Lipopolysaccharides results in increased phosphorylation of EIF2S1 protein CTD PMID:30794626 lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of EIF2S1 protein CTD PMID:31654708 lipopolysaccharide multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF2S1 protein] CTD PMID:31654708 losartan multiple interactions ISO RGD:620963 6480464 Losartan inhibits the reaction [AGT protein results in increased phosphorylation of EIF2S1 protein] CTD PMID:25398788 luteolin multiple interactions ISO RGD:735608 6480464 Luteolin inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein], Luteolin inhibits the reaction [Tunicamycin results in increased phosphorylation of EIF2S1 protein] CTD PMID:32407927 manganese atom multiple interactions ISO RGD:620963 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2S1 protein CTD PMID:32574669 manganese(0) multiple interactions ISO RGD:620963 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2S1 protein CTD PMID:32574669 manganese(II) chloride increases phosphorylation ISO RGD:735608 6480464 manganese chloride results in increased phosphorylation of EIF2S1 protein CTD PMID:23764342 manganese(II) chloride multiple interactions ISO RGD:620963 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2S1 protein, manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein] CTD PMID:23948121 , PMID:32574669 melatonin multiple interactions ISO RGD:620963 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:28070110 methamphetamine multiple interactions ISO RGD:620963 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:28070110 methamphetamine increases phosphorylation ISO RGD:620963 6480464 Methamphetamine results in increased phosphorylation of EIF2S1 protein CTD PMID:28070110 methapyrilene increases expression ISO RGD:620963 6480464 Methapyrilene results in increased expression of EIF2S1 mRNA CTD PMID:17450226 methylmercury chloride increases phosphorylation EXP 6480464 methylmercuric chloride results in increased phosphorylation of EIF2S1 protein CTD PMID:31330229 methylmercury chloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2S1 protein], AKT1 protein mutant form inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2S1 protein] CTD PMID:31330229 mevastatin multiple interactions EXP 6480464 EIF2S1 protein modified form inhibits the reaction [mevastatin results in decreased expression of DDIT3 mRNA] more ... CTD PMID:16330322 minocycline multiple interactions EXP 6480464 Minocycline inhibits the reaction [APP gene mutant form results in increased phosphorylation of EIF2S1 protein] CTD PMID:17406652 minocycline increases phosphorylation ISO RGD:620963 6480464 Minocycline results in increased phosphorylation of EIF2S1 protein CTD PMID:22245251 minocycline multiple interactions ISO RGD:620963 6480464 Minocycline inhibits the reaction [APP protein alternative form results in increased phosphorylation of EIF2S1 protein] CTD PMID:17406652 mitoxantrone affects response to substance ISO RGD:735608 6480464 EIF2S1 protein affects the susceptibility to Mitoxantrone CTD PMID:16217747 N-acetyl-L-cysteine multiple interactions ISO RGD:735608 6480464 Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:15788408 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:620963 6480464 Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:16324875 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [6-formylindolo3 more ... CTD PMID:21911445 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases phosphorylation EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein CTD PMID:21090173 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases phosphorylation ISO RGD:735608 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein CTD PMID:28359145 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:735608 6480464 [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein], PTPN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein] CTD PMID:25568320 , PMID:28359145 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases phosphorylation ISO RGD:620963 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein CTD PMID:23684743 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:735608 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EIF2S1 protein modified form CTD PMID:22321511 N-methyl-4-phenylpyridinium increases phosphorylation ISO RGD:735608 6480464 1-Methyl-4-phenylpyridinium results in increased phosphorylation of EIF2S1 protein CTD PMID:24810058 N-methylnicotinate multiple interactions EXP 6480464 trigonelline inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein] CTD PMID:30208301 naloxone multiple interactions ISO RGD:735608 6480464 Naloxone inhibits the reaction [Oxycodone results in increased phosphorylation of EIF2S1 protein] CTD PMID:26377394 nefazodone increases expression ISO RGD:620963 6480464 nefazodone results in increased expression of EIF2S1 mRNA CTD PMID:24136188 niclosamide increases phosphorylation ISO RGD:735608 6480464 Niclosamide results in increased phosphorylation of EIF2S1 protein CTD PMID:26917416 nicotine increases phosphorylation ISO RGD:620963 6480464 Nicotine results in increased phosphorylation of EIF2S1 protein CTD PMID:26803847 nimesulide increases expression ISO RGD:620963 6480464 nimesulide results in increased expression of EIF2S1 mRNA CTD PMID:24136188 okadaic acid increases phosphorylation ISO RGD:620963 6480464 Okadaic Acid results in increased phosphorylation of EIF2S1 protein CTD PMID:26732598 oxycodone multiple interactions ISO RGD:735608 6480464 Naloxone inhibits the reaction [Oxycodone results in increased phosphorylation of EIF2S1 protein] CTD PMID:26377394 oxycodone increases phosphorylation ISO RGD:735608 6480464 Oxycodone results in increased phosphorylation of EIF2S1 protein CTD PMID:26377394 oxycodone increases phosphorylation ISO RGD:620963 6480464 Oxycodone results in increased phosphorylation of EIF2S1 protein CTD PMID:26377394 ozone multiple interactions ISO RGD:620963 6480464 [Ozone co-treated with Chlorine] results in decreased expression of EIF2S1 mRNA CTD PMID:18636392 paclitaxel affects phosphorylation ISO RGD:735608 6480464 Paclitaxel affects the phosphorylation of EIF2S1 protein CTD PMID:29053414 paracetamol increases phosphorylation EXP 6480464 Acetaminophen results in increased phosphorylation of EIF2S1 protein CTD PMID:19931551 paracetamol multiple interactions EXP 6480464 Guanabenz inhibits the reaction [Acetaminophen results in decreased phosphorylation of EIF2S1 protein] CTD PMID:31524377 paracetamol decreases phosphorylation EXP 6480464 Acetaminophen results in decreased phosphorylation of EIF2S1 protein CTD PMID:31524377 paraquat increases phosphorylation ISO RGD:620963 6480464 Paraquat results in increased phosphorylation of EIF2S1 protein CTD PMID:22245251 paraquat multiple interactions ISO RGD:735608 6480464 EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]] more ... CTD PMID:28986289 paraquat increases expression ISO RGD:735608 6480464 Paraquat results in increased expression of EIF2S1 protein modified form CTD PMID:28986289 paraquat increases phosphorylation EXP 6480464 Paraquat results in increased phosphorylation of EIF2S1 protein CTD PMID:27442881 perfluorooctanoic acid increases expression ISO RGD:620963 6480464 perfluorooctanoic acid results in increased expression of EIF2S1 mRNA CTD PMID:19162173 perfluorooctanoic acid increases phosphorylation EXP 6480464 perfluorooctanoic acid results in increased phosphorylation of EIF2S1 protein CTD PMID:32578922 phenethyl isothiocyanate increases phosphorylation EXP 6480464 phenethyl isothiocyanate results in increased phosphorylation of EIF2S1 protein CTD PMID:27579538 phenethyl isothiocyanate increases phosphorylation ISO RGD:735608 6480464 phenethyl isothiocyanate results in increased phosphorylation of EIF2S1 protein CTD PMID:27579538 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of EIF2S1 mRNA CTD PMID:19710929 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of EIF2S1 mRNA CTD PMID:23811191 pirinixic acid increases expression ISO RGD:620963 6480464 pirinixic acid results in increased expression of EIF2S1 mRNA CTD PMID:19162173 piroxicam decreases expression ISO RGD:735608 6480464 Piroxicam results in decreased expression of EIF2S1 mRNA CTD PMID:21858171 potassium atom increases phosphorylation ISO RGD:620963 6480464 Potassium deficiency results in increased phosphorylation of EIF2S1 protein CTD PMID:19046382 proanthocyanidin multiple interactions ISO RGD:620963 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of EIF2S1 protein] CTD PMID:25088297 pyrazinecarboxamide increases phosphorylation ISO RGD:735608 6480464 Pyrazinamide results in increased phosphorylation of EIF2S1 protein CTD PMID:28063906 pyrazinecarboxamide multiple interactions ISO RGD:735608 6480464 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2S1 protein] CTD PMID:28063906 pyrazinecarboxamide multiple interactions ISO RGD:620963 6480464 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2S1 protein] CTD PMID:28063906 pyrazinecarboxamide increases phosphorylation ISO RGD:620963 6480464 Pyrazinamide results in increased phosphorylation of EIF2S1 protein CTD PMID:28063906 quercetin increases expression ISO RGD:735608 6480464 Quercetin results in increased expression of EIF2S1 mRNA, Quercetin results in increased expression of EIF2S1 protein modified form CTD PMID:19017364 , PMID:21632981 quercetin increases phosphorylation ISO RGD:735608 6480464 Quercetin results in increased phosphorylation of EIF2S1 protein CTD PMID:25611565 quercetin multiple interactions ISO RGD:735608 6480464 salubrinal promotes the reaction [Quercetin results in increased phosphorylation of EIF2S1 protein], ursodoxicoltaurine inhibits the reaction [Quercetin results in increased phosphorylation of EIF2S1 protein] CTD PMID:25611565 quinolinic acid increases phosphorylation ISO RGD:620963 6480464 Quinolinic Acid results in increased phosphorylation of EIF2S1 protein CTD PMID:24211709 quinolinic acid multiple interactions ISO RGD:620963 6480464 [Quinolinic Acid co-treated with GW 506033X] results in increased phosphorylation of EIF2S1 protein CTD PMID:24211709 raloxifene decreases expression ISO RGD:735608 6480464 Raloxifene Hydrochloride results in decreased expression of EIF2S1 mRNA CTD PMID:16514628 resveratrol increases phosphorylation ISO RGD:735608 6480464 resveratrol results in increased phosphorylation of EIF2S1 protein CTD PMID:17914584 , PMID:22898769 resveratrol multiple interactions ISO RGD:735608 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of EIF2S1 protein modified form] CTD PMID:24224909 rifampicin increases phosphorylation ISO RGD:620963 6480464 Rifampin results in increased phosphorylation of EIF2S1 protein CTD PMID:24638036 rotenone increases expression ISO RGD:735608 6480464 Rotenone results in increased expression of EIF2S1 protein CTD PMID:19233273 , PMID:30141137 rotenone multiple interactions ISO RGD:735608 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of EIF2S1 protein], PTPN1 protein affects the reaction [Rotenone results in increased phosphorylation of EIF2S1 protein] CTD PMID:28359145 , PMID:30141137 rotenone multiple interactions ISO RGD:620963 6480464 salubrinal inhibits the reaction [Rotenone results in decreased phosphorylation of EIF2S1 protein] CTD PMID:26446018 rotenone decreases phosphorylation ISO RGD:620963 6480464 Rotenone results in decreased phosphorylation of EIF2S1 protein CTD PMID:26446018 rotenone decreases phosphorylation EXP 6480464 Rotenone results in decreased phosphorylation of EIF2S1 protein CTD PMID:25428620 rotenone multiple interactions EXP 6480464 salubrinal inhibits the reaction [Rotenone results in decreased phosphorylation of EIF2S1 protein] CTD PMID:25428620 rotenone increases phosphorylation ISO RGD:735608 6480464 Rotenone results in increased phosphorylation of EIF2S1 protein CTD PMID:19233273 more ... salubrinal multiple interactions ISO RGD:735608 6480464 [salubrinal co-treated with EPO protein] results in increased phosphorylation of EIF2S1 protein more ... CTD PMID:21555338 more ... salubrinal increases phosphorylation EXP 6480464 salubrinal results in increased phosphorylation of EIF2S1 protein CTD PMID:29380555 salubrinal multiple interactions EXP 6480464 salubrinal inhibits the reaction [Rotenone results in decreased phosphorylation of EIF2S1 protein] CTD PMID:25428620 salubrinal increases phosphorylation ISO RGD:620963 6480464 salubrinal results in increased phosphorylation of EIF2S1 protein CTD PMID:24932542 salubrinal increases expression ISO RGD:735608 6480464 salubrinal results in increased expression of EIF2S1 protein modified form CTD PMID:25950987 , PMID:28986289 salubrinal multiple interactions ISO RGD:620963 6480464 [salubrinal results in increased expression of EIF2S1 protein modified form] which results in increased phosphorylation of MAPK1 protein more ... CTD PMID:21147958 more ... salubrinal increases phosphorylation ISO RGD:735608 6480464 salubrinal results in increased phosphorylation of EIF2S1 protein CTD PMID:21809093 , PMID:23690448 Salvianolic acid A multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF2S1 protein] CTD PMID:31654708 SB 203580 increases phosphorylation EXP 6480464 SB 203580 results in increased phosphorylation of EIF2S1 protein CTD PMID:21090173 SB 431542 multiple interactions ISO RGD:735608 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of EIF2S1 mRNA CTD PMID:27188386 scopolamine increases expression ISO RGD:620963 6480464 Scopolamine results in increased expression of EIF2S1 mRNA CTD PMID:12818353 selenomethionine multiple interactions ISO RGD:620963 6480464 Selenomethionine inhibits the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein] CTD PMID:29454614 sertraline increases phosphorylation ISO RGD:735608 6480464 Sertraline results in increased phosphorylation of EIF2S1 protein CTD PMID:24865413 sirolimus multiple interactions ISO RGD:620963 6480464 Sirolimus inhibits the reaction [cadmium acetate results in increased phosphorylation of EIF2S1 protein] CTD PMID:29870746 sodium arsenite multiple interactions ISO RGD:735608 6480464 Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of EIF2S1 protein] CTD PMID:15788408 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of EIF2S1 protein CTD PMID:29044176 sodium arsenite multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of EIF2S1 protein] more ... CTD PMID:16330322 , PMID:21911445 sodium arsenite increases phosphorylation ISO RGD:735608 6480464 sodium arsenite results in increased phosphorylation of EIF2S1 protein CTD PMID:15788408 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of EIF2S1 protein CTD PMID:16330322 more ... sodium dichromate increases expression ISO RGD:620963 6480464 sodium bichromate results in increased expression of EIF2S1 mRNA CTD PMID:22561333 , PMID:25993096 staurosporine increases phosphorylation EXP 6480464 Staurosporine results in increased phosphorylation of EIF2S1 protein CTD PMID:21090173 succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of EIF2S1 mRNA CTD PMID:21641980 sulforaphane multiple interactions ISO RGD:735608 6480464 sulforafan promotes the reaction [arsenic trioxide results in increased expression of EIF2S1 protein modified form] CTD PMID:22922937 sulforaphane increases expression ISO RGD:735608 6480464 sulforafan results in increased expression of EIF2S1 protein modified form CTD PMID:22922937 T-2 toxin increases phosphorylation ISO RGD:620963 6480464 T-2 Toxin results in increased phosphorylation of EIF2S1 protein CTD PMID:29454614 T-2 toxin multiple interactions ISO RGD:620963 6480464 Selenomethionine inhibits the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein] CTD PMID:29454614 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of EIF2S1 mRNA CTD PMID:17555576 tauroursodeoxycholic acid multiple interactions ISO RGD:735608 6480464 ursodoxicoltaurine inhibits the reaction [Quercetin results in increased phosphorylation of EIF2S1 protein], ursodoxicoltaurine inhibits the reaction [ursolic acid results in increased phosphorylation of EIF2S1 protein] CTD PMID:24802810 , PMID:25611565 tenofovir disoproxil fumarate affects phosphorylation ISO RGD:735608 6480464 Tenofovir affects the phosphorylation of EIF2S1 protein CTD PMID:27041070 testosterone enanthate affects expression ISO RGD:735608 6480464 testosterone enanthate affects the expression of EIF2S1 mRNA CTD PMID:17440010 tetrachloromethane increases phosphorylation EXP 6480464 Carbon Tetrachloride results in increased phosphorylation of EIF2S1 protein CTD PMID:25827057 tetrachloromethane multiple interactions ISO RGD:620963 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of EIF2S1 mRNA] CTD PMID:31150632 tetrachloromethane increases expression ISO RGD:620963 6480464 Carbon Tetrachloride results in increased expression of EIF2S1 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 1-trifluoromethoxyphenyl-3-1-propionylpiperidine-4-ylurea inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of EIF2S1 protein] CTD PMID:25827057 thapsigargin multiple interactions ISO RGD:735608 6480464 1-1-methanesulfonylpiperidin-4-yl-3-4-trifluoromethoxyphenylurea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:20022965 more ... thapsigargin decreases phosphorylation EXP 6480464 Thapsigargin results in decreased phosphorylation of EIF2S1 protein CTD PMID:29109149 thapsigargin increases expression ISO RGD:620963 6480464 Thapsigargin results in increased expression of EIF2S1 mRNA CTD PMID:28844859 thapsigargin increases expression ISO RGD:735608 6480464 Thapsigargin results in increased expression of EIF2S1 protein modified form CTD PMID:24224909 thapsigargin decreases response to substance EXP 6480464 EIF2S1 protein mutant form results in decreased susceptibility to Thapsigargin CTD PMID:24315374 thapsigargin increases phosphorylation ISO RGD:735608 6480464 Thapsigargin results in increased phosphorylation of EIF2S1 protein CTD PMID:17553788 more ... thapsigargin increases phosphorylation EXP 6480464 Thapsigargin results in increased phosphorylation of EIF2S1 protein CTD PMID:23576437 more ... thapsigargin multiple interactions EXP 6480464 1-1-methanesulfonylpiperidin-4-yl-3-4-trifluoromethoxyphenylurea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein] more ... CTD PMID:22509299 more ... thapsigargin multiple interactions ISO RGD:620963 6480464 EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein], salubrinal inhibits the reaction [Thapsigargin results in increased expression of EIF2S1 mRNA] CTD PMID:16324875 , PMID:28844859 thapsigargin increases phosphorylation ISO RGD:620963 6480464 Thapsigargin results in increased phosphorylation of EIF2S1 protein CTD PMID:16324875 , PMID:28844859 thioacetamide increases expression ISO RGD:620963 6480464 Thioacetamide results in increased expression of EIF2S1 mRNA CTD PMID:23411599 thiostrepton increases expression ISO RGD:735608 6480464 Thiostrepton results in increased expression of EIF2S1 protein modified form CTD PMID:22321511 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of EIF2S1 mRNA CTD PMID:29264374 titanium dioxide increases phosphorylation EXP 6480464 titanium dioxide results in increased phosphorylation of EIF2S1 protein CTD PMID:31769605 tributylstannane multiple interactions ISO RGD:735608 6480464 Dantrolene inhibits the reaction [tributyltin results in increased phosphorylation of EIF2S1 protein] CTD PMID:23743301 tributylstannane increases phosphorylation ISO RGD:735608 6480464 tributyltin results in increased phosphorylation of EIF2S1 protein CTD PMID:23743301 Tributyltin oxide increases expression ISO RGD:735608 6480464 bistri-n-butyltinoxide results in increased expression of EIF2S1 mRNA CTD PMID:21601586 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of EIF2S1 mRNA CTD PMID:19448997 triclocarban increases expression ISO RGD:735608 6480464 triclocarban results in increased expression of EIF2S1 protein modified form CTD PMID:30592132 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of EIF2S1 mRNA CTD PMID:19042947 troglitazone decreases phosphorylation ISO RGD:735608 6480464 troglitazone results in decreased phosphorylation of EIF2S1 protein CTD PMID:11834241 trovafloxacin decreases expression ISO RGD:620963 6480464 trovafloxacin results in decreased expression of EIF2S1 mRNA CTD PMID:24136188 tunicamycin multiple interactions ISO RGD:735608 6480464 [Tunicamycin results in increased phosphorylation of EIF2S1 protein] which results in decreased expression of MCL1 protein more ... CTD PMID:16357177 more ... tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of EIF2S1 protein modified form CTD PMID:25160872 tunicamycin increases expression ISO RGD:620963 6480464 Tunicamycin results in increased expression of EIF2S1 mRNA CTD PMID:28844859 tunicamycin increases expression ISO RGD:735608 6480464 Tunicamycin results in increased expression of EIF2S1 protein modified form CTD PMID:24224909 , PMID:30592132 tunicamycin increases phosphorylation ISO RGD:620963 6480464 Tunicamycin results in increased phosphorylation of EIF2S1 protein CTD PMID:24892553 , PMID:28844859 tunicamycin multiple interactions ISO RGD:620963 6480464 Guanabenz promotes the reaction [Tunicamycin results in increased phosphorylation of EIF2S1 protein], salubrinal inhibits the reaction [Tunicamycin results in increased expression of EIF2S1 mRNA] CTD PMID:24892553 , PMID:28844859 tunicamycin increases phosphorylation ISO RGD:735608 6480464 Tunicamycin results in increased phosphorylation of EIF2S1 protein CTD PMID:16357177 more ... tunicamycin increases phosphorylation EXP 6480464 Tunicamycin results in increased phosphorylation of EIF2S1 protein CTD PMID:24648495 more ... tunicamycin multiple interactions EXP 6480464 EIF2AK3 gene mutant form inhibits the reaction [Tunicamycin results in increased expression of EIF2S1 protein] more ... CTD PMID:16330322 more ... ursolic acid multiple interactions ISO RGD:735608 6480464 EIF2AK3 mutant form inhibits the reaction [ursolic acid results in increased phosphorylation of EIF2S1 protein], ursodoxicoltaurine inhibits the reaction [ursolic acid results in increased phosphorylation of EIF2S1 protein] CTD PMID:24802810 ursolic acid increases phosphorylation ISO RGD:735608 6480464 ursolic acid results in increased phosphorylation of EIF2S1 protein CTD PMID:24802810 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of EIF2S1 mRNA CTD PMID:17963808 valproic acid multiple interactions ISO RGD:735608 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of EIF2S1 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:735608 6480464 Valproic Acid results in increased expression of EIF2S1 mRNA CTD PMID:23179753 , PMID:26272509 valproic acid affects expression ISO RGD:735608 6480464 Valproic Acid affects the expression of EIF2S1 mRNA CTD PMID:25979313 zidovudine increases phosphorylation ISO RGD:735608 6480464 Zidovudine results in increased phosphorylation of EIF2S1 protein CTD PMID:27041070 zinc oxide increases phosphorylation EXP 6480464 Zinc Oxide analog results in increased phosphorylation of EIF2S1 protein CTD PMID:25680694
