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Gene: EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha) Chlorocebus sabaeus

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Symbol:

EIF2S1

Name:

eukaryotic translation initiation factor 2 subunit alpha

RGD ID:

18538690

Description:

ENCODES a protein that exhibits nucleic acid binding (inferred); ribosome binding (inferred); RNA binding (inferred); INVOLVED IN cellular response to heat (ortholog); negative regulation of guanyl-nucleotide exchange factor activity (ortholog); positive regulation of type B pancreatic cell apoptotic process (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH Alcoholic Liver Diseases (ortholog); Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); FOUND IN eukaryotic translation initiation factor 2 complex (ortholog); glial limiting end-foot (ortholog); translation initiation ternary complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

eukaryotic translation initiation factor 2 subunit 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	44,599,017 - 44,623,723 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	44,598,287 - 44,623,298 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	32,828,857 - 32,856,268 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF2S1	Green Monkey	Alcoholic Liver Diseases		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:21059295 and REF_RGD_ID:10395351
EIF2S1	Green Monkey	Alzheimer's disease		ISO	EIF2S1 (Homo sapiens)	9068941		RGD	PMID:16691116 and REF_RGD_ID:10395316
EIF2S1	Green Monkey	Alzheimer's disease	severity	ISO	EIF2S1 (Homo sapiens)	9068941		RGD	PMID:16954686 and REF_RGD_ID:10395343
EIF2S1	Green Monkey	Alzheimer's disease		ISO	Eif2s1 (Mus musculus)	9068941	protein:increased phosphorylation:hippocampus	RGD	PMID:24315369 and REF_RGD_ID:10395344
EIF2S1	Green Monkey	Brain Hypoxia-Ischemia		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:8092984 and REF_RGD_ID:10395352
EIF2S1	Green Monkey	Brain Injuries		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:11526986 and REF_RGD_ID:10395358
EIF2S1	Green Monkey	middle cerebral artery infarction	treatment	ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:19763736 more ...
EIF2S1	Green Monkey	Reperfusion Injury		ISO	Eif2s1 (Rattus norvegicus)	9068941	protein:increased phosphorylation:kidney	RGD	PMID:15936177 and REF_RGD_ID:1581062
EIF2S1	Green Monkey	Sarcopenia		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:15187001 and REF_RGD_ID:10395315
EIF2S1	Green Monkey	Sepsis		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:8141277 and REF_RGD_ID:10395355
EIF2S1	Green Monkey	transient cerebral ischemia		ISO	Eif2s1 (Mus musculus)	9068941		RGD	PMID:11520898 and REF_RGD_ID:10395353
EIF2S1	Green Monkey	transient cerebral ischemia		ISO	Eif2s1 (Rattus norvegicus)	9068941	associated with Heart Arrest	RGD	PMID:10541873 and REF_RGD_ID:11041881

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF2S1	Green Monkey	Leber congenital amaurosis 13		ISO	EIF2S1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Leber congenital amaurosis 13	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF2S1	Green Monkey	Alzheimer's disease		ISO	EIF2S1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:17406652
EIF2S1	Green Monkey	cognitive disorder		ISO	EIF2S1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:17406652
EIF2S1	Green Monkey	Nerve Degeneration		ISO	EIF2S1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16492139
EIF2S1	Green Monkey	osteosarcoma		ISO	EIF2S1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:14767549
EIF2S1	Green Monkey	status epilepticus		ISO	EIF2S1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:15003282

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF2S1	Green Monkey	cellular response to amino acid starvation	involved_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	cellular response to heat		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:3500171 more ...
EIF2S1	Green Monkey	cellular response to oxidative stress	involved_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	cellular response to UV	involved_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	HRI-mediated signaling	involved_in	IEA	UniProtKB:P05198 and ensembl:ENSP00000256383	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	mitophagy	involved_in	IEA	UniProtKB:P05198 and ensembl:ENSP00000256383	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	negative regulation of guanyl-nucleotide exchange factor activity		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:9582312 and REF_RGD_ID:1581075
EIF2S1	Green Monkey	negative regulation of translational initiation in response to stress	involved_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	PERK-mediated unfolded protein response	involved_in	IEA	UniProtKB:P05198 and ensembl:ENSP00000256383	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	positive regulation of type B pancreatic cell apoptotic process		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:17158450 and REF_RGD_ID:10395350
EIF2S1	Green Monkey	protein autophosphorylation	acts_upstream_of_or_within	ISO	Eif2s1 (Mus musculus)	9068941	PMID:19139267	MGI	PMID:19139267
EIF2S1	Green Monkey	regulation of translation in response to endoplasmic reticulum stress	involved_in	IEA	UniProtKB:P05198 and ensembl:ENSP00000256383	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	regulation of translational initiation in response to stress	acts_upstream_of_or_within	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	response to endoplasmic reticulum stress	involved_in	IEA	UniProtKB:P05198 more ...	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	response to kainic acid		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:17251432 and REF_RGD_ID:10755427
EIF2S1	Green Monkey	response to manganese-induced endoplasmic reticulum stress	involved_in	ISO	Eif2s1 (Rattus norvegicus)	9068941	PMID:23934647	ParkinsonsUK-UCL	PMID:23934647 and REF_RGD_ID:10047151
EIF2S1	Green Monkey	stress granule assembly	involved_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	translation	involved_in	IEA	UniProtKB-KW:KW-0648	150520179		UniProt	GO_REF:0000043
EIF2S1	Green Monkey	translation	acts_upstream_of_or_within	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	translational initiation	involved_in	IEA	PANTHER:PTN000063920	150520179		TreeGrafter	GO_REF:0000118
EIF2S1	Green Monkey	translational initiation	involved_in	IEA	UniProtKB-KW:KW-0396	150520179		UniProt	GO_REF:0000043
EIF2S1	Green Monkey	translational initiation	involved_in	IEA	UniProtKB:P05198 more ...	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF2S1	Green Monkey	cytoplasm	located_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	cytoplasmic stress granule	located_in	IEA	UniProtKB-SubCell:SL-0496	150520179		UniProt	GO_REF:0000044
EIF2S1	Green Monkey	cytoplasmic stress granule	located_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	cytosol	located_in	IEA	UniProtKB:P05198 more ...	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	eukaryotic 48S preinitiation complex	part_of	IEA	PANTHER:PTN000063920	150520179		TreeGrafter	GO_REF:0000118
EIF2S1	Green Monkey	eukaryotic translation initiation factor 2 complex	part_of	IEA	PANTHER:PTN000063920	150520179		TreeGrafter	GO_REF:0000118
EIF2S1	Green Monkey	eukaryotic translation initiation factor 2 complex	part_of	IEA	UniProtKB:P05198 and ensembl:ENSP00000256383	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	eukaryotic translation initiation factor 2 complex		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:2450747 and REF_RGD_ID:10395356
EIF2S1	Green Monkey	glial limiting end-foot		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:9397028 and REF_RGD_ID:10395349
EIF2S1	Green Monkey	mitochondrion	is_active_in	IEA	UniProtKB:P05198 and ensembl:ENSP00000256383	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	nucleus	located_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	synapse	is_active_in	IEA	UniProtKB:Q6ZWX6 and ensembl:ENSMUSP00000071214	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	translation initiation ternary complex		ISO	Eif2s1 (Rattus norvegicus)	9068941		RGD	PMID:2450747 and REF_RGD_ID:10395356

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF2S1	Green Monkey	nucleic acid binding	enables	IEA	InterPro:IPR003029	150520179		InterPro	GO_REF:0000002
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49242	9068941	PMID:3384085	UniProt	PMID:3384085 and REF_RGD_ID:8554720
EIF2S1	Green Monkey	protein binding	enables	ISO	PR:O08663	9068941	PMID:15544353	MGI	PMID:15544353
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q9Z2R9	9068941	PMID:21223507	IntAct	PMID:21223507
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q9Z2B5	9068941	PMID:9930704	ParkinsonsUK-UCL	PMID:9930704
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P20042	9068941	PMID:16932749 and PMID:28514442	IntAct	PMID:16932749 and PMID:28514442
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P12814 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P19525	9068941	PMID:18971339 and PMID:9431994	IntAct	PMID:18971339 and PMID:9431994
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P19525 more ...	9068941	PMID:16288713	IntAct	PMID:16288713
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q8NE71 and UniProtKB:Q8NE71-2	9068941	PMID:17894550	UniProt	PMID:17894550
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P41091	9068941	PMID:35271311 and PMID:37507029	IntAct	PMID:35271311 and PMID:37507029
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:O00571	9068941	PMID:18596238 and PMID:22323517	IntAct	PMID:18596238 and PMID:22323517
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P20042 more ...	9068941	PMID:33961781	IntAct	PMID:33961781
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P17074	9068941	PMID:3384085	UniProt	PMID:3384085 and REF_RGD_ID:8554720
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q9Y4P3	9068941	PMID:25393282	ParkinsonsUK-UCL	PMID:25393282
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P62850	9068941	PMID:3384085	UniProt	PMID:3384085 and REF_RGD_ID:8554720
EIF2S1	Green Monkey	protein binding		ISO	Eif2s2 (Rattus norvegicus) and Eif2s3 (Rattus norvegicus)	9068941		RGD	PMID:2450747 and REF_RGD_ID:10395356
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q64350	9068941	PMID:11500362	UniProt	PMID:11500362
EIF2S1	Green Monkey	protein binding	enables	ISO	UniProtKB:P62136	9068941	PMID:26095357	IntAct	PMID:26095357
EIF2S1	Green Monkey	ribosome binding	enables	IEA	PANTHER:PTN000063920	150520179		TreeGrafter	GO_REF:0000118
EIF2S1	Green Monkey	ribosome binding	enables	IEA	UniProtKB:P05198 and ensembl:ENSP00000256383	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	RNA binding	enables	IEA	InterPro:IPR011488 and InterPro:IPR044126	150520179		InterPro	GO_REF:0000002
EIF2S1	Green Monkey	translation initiation factor activity	enables	IEA	PANTHER:PTN000063920	150520179		TreeGrafter	GO_REF:0000118
EIF2S1	Green Monkey	translation initiation factor activity	enables	IEA	UniProtKB:P05198 more ...	150520179		Ensembl	GO_REF:0000107
EIF2S1	Green Monkey	translation initiation factor activity	enables	IEA	UniProtKB-KW:KW-0396	150520179		UniProt	GO_REF:0000043
EIF2S1	Green Monkey	translation initiation factor activity	enables	IEA	InterPro:IPR011488	150520179		InterPro	GO_REF:0000002

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF2S1	Green Monkey	translation initiation pathway		ISO	EIF2S1 (Homo sapiens)	9068941		RGD	PMID:22815232 more ...

PMID:22301074	PMID:30032202

EIF2S1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	44,599,017 - 44,623,723 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	44,598,287 - 44,623,298 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	32,828,857 - 32,856,268 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

EIF2S1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	67,360,328 - 67,386,516 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	67,360,328 - 67,386,516 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	67,827,045 - 67,853,233 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	66,896,787 - 66,922,986 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	66,896,837 - 66,921,909	NCBI
Celera	14	47,886,088 - 47,912,287 (+)	NCBI		Celera
Cytogenetic Map	14	q23.3	NCBI
HuRef	14	47,996,958 - 48,023,152 (+)	NCBI		HuRef
CHM1_1	14	67,765,718 - 67,791,923 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	61,567,453 - 61,593,639 (+)	NCBI		T2T-CHM13v2.0

Eif2s1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	78,908,846 - 78,933,784 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	78,908,593 - 78,933,784 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	78,862,072 - 78,887,010 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	78,861,819 - 78,887,010 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	79,963,059 - 79,987,997 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	79,780,910 - 79,804,371 (+)	NCBI		MGSCv36	mm8
Celera	12	80,326,532 - 80,351,470 (+)	NCBI		Celera
Cytogenetic Map	12	C3	NCBI
cM Map	12	35.51	NCBI

Eif2s1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	103,405,880 - 103,430,549 (+)	NCBI		GRCr8
mRatBN7.2	6	97,672,829 - 97,697,499 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	97,672,766 - 97,706,225 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	98,102,349 - 98,127,010 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	98,401,511 - 98,426,172 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	97,788,465 - 97,813,132 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	102,048,372 - 102,073,041 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	102,048,372 - 102,073,041 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	111,422,397 - 111,447,066 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	101,495,444 - 101,520,113 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	96,060,793 - 96,085,462 (+)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

Eif2s1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	2,838,785 - 2,855,172 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955466	2,838,785 - 2,855,443 (-)	NCBI	ChiLan1.0	ChiLan1.0

EIF2S1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	68,465,765 - 68,489,430 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	67,682,677 - 67,708,545 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	47,935,691 - 47,960,055 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	66,813,953 - 66,839,866 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	66,813,953 - 66,839,866 (+)	Ensembl	panpan1.1		panPan2

EIF2S1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	41,354,400 - 41,371,676 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	41,351,244 - 41,371,056 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	41,045,920 - 41,062,790 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	41,581,554 - 41,598,447 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	41,581,926 - 41,600,736 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	41,200,418 - 41,217,284 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	41,273,999 - 41,290,966 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	41,632,932 - 41,649,922 (+)	NCBI		UU_Cfam_GSD_1.0

Eif2s1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	63,422,172 - 63,445,032 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	10,745,923 - 10,773,199 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	10,746,687 - 10,769,304 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EIF2S1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	91,085,335 - 91,109,827 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	91,085,025 - 91,109,835 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	97,394,525 - 97,417,715 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Eif2s1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	33,621,782 - 33,640,549 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	33,624,246 - 33,640,667 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in EIF2S1
365 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20


RefSeq Transcripts	XM_007987056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007987057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000011418 ⟹ ENSCSAP00000009490

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	24	44,598,287 - 44,623,298 (+)	Ensembl

RefSeq Acc Id:

XM_007987056 ⟹ XP_007985247

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	24	44,599,017 - 44,623,723 (+)	NCBI
Vero_WHO_p1.0	NW_023666053	32,828,857 - 32,856,268 (+)	NCBI

Sequence:

show sequence

TTCCGCATGCGCAGTCGGGTGACCGAAGCGCACGCTGAGGAGGATCGGCGGCCGGTGAGGGAGAAGCTAGTCTGGTCTCTCTGATTGAAGGCGGCGGCTCTGGTGTCCACTGCGGGAATCACACACAT
ACCTCAGAATGCCGGGTCTAAGTTGTAGATTTTATCAACACAAATTTCCTGAGGTGGAAGATGTAGTGATGGTGAATGTCAGATCCATTGCTGAAATGGGGGCTTATGTCAGCTTGCTGGAATACAAC
AACATTGAAGGCATGATTCTACTTAGTGAATTATCTAGAAGGCGTATCCGTTCTATCAACAAACTCATCCGAATTGGCAGAAATGAGTGTGTGGTTGTCATTAGGGTGGACAAAGAAAAAGGATATAT
TGATTTGTCAAAAAGAAGAGTTTCTCCAGAGGAAGCAATCAAATGTGAAGACAAATTCACAAAATCGAAAACTGTTTATAGCATTCTTCGTCATGTTGCTGAGGTGTTAGAATACACCAAGGATGAGC
AGCTGGAAAGCCTATTCCAGAGGACTGCCTGGGTCTTTGATGACAAGTACAAGAGACCTGGATATGGTGCCTATGATGCATTTAAGCATGCAGTCTCAGACCCATCTATTTTGGATAGTTTAGATTTG
AATGAAGATGAACGGGAAGTACTCATTAATAATATTAATAGGCGCTTGACCCCACAGGCTGTCAAAATTCGAGCAGATATTGAAGTGGCTTGTTATGGTTATGAAGGCATTGATGCTGTAAAAGAAGC
CCTAAGAGCGGGTTTGAATTGTTCTACAGAAAACATGCCCATTAAGATTAATCTAATAGCTCCTCCTCGGTATGTAATGACTACAACAACCCTGGAGAGAACAGAAGGCCTTTCTGTCCTCAGTCAAG
CTATGGCTGTTATCAAAGAAAAGATTGAGGAAAAGAGGGGTGTGTTCAATGTTCAAATGGAGCCCAAAGTGGTCACAGATACAGATGAGACTGAACTTGCGAGGCAGATGGAGAGGCTTGAAAGAGAA
AATGCCGAAGTGGATGGAGATGATGATGCAGAAGAAATGGAAGCCAAAGCTGAAGATTAACTTTGTGGGAAACAGAGTCCAATTTAAGGAACACAGAGCAGCCCTTCCTGGCTGTAAATCCTAGACTT
GAAAGTTTTCCAGTATTGAAAACTTCAAAGCTGAATATTTTTTATTTCTAAGTATTTAAATGTTCTAACAGATCGGAACATGAAATGCCCTCCTAAATGTCAGCTGTTGTCACACAGTAGCTCCAACA
CTTTGAGCATTTTTAAGGGAGTGGCCTCATTTCACTAGAGACAAATCTTTAAGAATAGTTCTAAAATTGGGCTTGTGATTTCCATTTCTGATGTCTCCAGATTGGCACCCCTTTCTAGTTCAATGCCT
CACGAGATTTACCAGGGGCATCCAAAGCAAACAATCCCAATCTTTCTATATAAAATGTATTCAAACAAACATCAAATAAATTTCTGGGATATTTAACTATA

hide sequence

RefSeq Acc Id:

XM_007987057 ⟹ XP_007985248

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	24	44,599,181 - 44,623,723 (+)	NCBI
Vero_WHO_p1.0	NW_023666053	32,829,124 - 32,856,268 (+)	NCBI

Sequence:

show sequence

GAACTCACTTTCGTTTGTGTCCAGTGACATGGGTGTTCGACAGCGGGTAGGCCCCGGGCTAACACCTCCCTTTCCCGTCCCTGCGCGGGAAGTGGCTGGACAGCACCGCCGCCACCCGCGCTGTCGTG
GGCCTCGTCGCCGGCTCCGTGTAGGTCATCCTGTGTTCCAGAGGCATCGTTGTTCCAGCAGAGGAATCTCGTGAAGGAAAGTGGGCCGAGTGGATTATACAGCCTCTACAATATGCCGAAAAATGCCG
GGTCTAAGTTGTAGATTTTATCAACACAAATTTCCTGAGGTGGAAGATGTAGTGATGGTGAATGTCAGATCCATTGCTGAAATGGGGGCTTATGTCAGCTTGCTGGAATACAACAACATTGAAGGCAT
GATTCTACTTAGTGAATTATCTAGAAGGCGTATCCGTTCTATCAACAAACTCATCCGAATTGGCAGAAATGAGTGTGTGGTTGTCATTAGGGTGGACAAAGAAAAAGGATATATTGATTTGTCAAAAA
GAAGAGTTTCTCCAGAGGAAGCAATCAAATGTGAAGACAAATTCACAAAATCGAAAACTGTTTATAGCATTCTTCGTCATGTTGCTGAGGTGTTAGAATACACCAAGGATGAGCAGCTGGAAAGCCTA
TTCCAGAGGACTGCCTGGGTCTTTGATGACAAGTACAAGAGACCTGGATATGGTGCCTATGATGCATTTAAGCATGCAGTCTCAGACCCATCTATTTTGGATAGTTTAGATTTGAATGAAGATGAACG
GGAAGTACTCATTAATAATATTAATAGGCGCTTGACCCCACAGGCTGTCAAAATTCGAGCAGATATTGAAGTGGCTTGTTATGGTTATGAAGGCATTGATGCTGTAAAAGAAGCCCTAAGAGCGGGTT
TGAATTGTTCTACAGAAAACATGCCCATTAAGATTAATCTAATAGCTCCTCCTCGGTATGTAATGACTACAACAACCCTGGAGAGAACAGAAGGCCTTTCTGTCCTCAGTCAAGCTATGGCTGTTATC
AAAGAAAAGATTGAGGAAAAGAGGGGTGTGTTCAATGTTCAAATGGAGCCCAAAGTGGTCACAGATACAGATGAGACTGAACTTGCGAGGCAGATGGAGAGGCTTGAAAGAGAAAATGCCGAAGTGGA
TGGAGATGATGATGCAGAAGAAATGGAAGCCAAAGCTGAAGATTAACTTTGTGGGAAACAGAGTCCAATTTAAGGAACACAGAGCAGCCCTTCCTGGCTGTAAATCCTAGACTTGAAAGTTTTCCAGT
ATTGAAAACTTCAAAGCTGAATATTTTTTATTTCTAAGTATTTAAATGTTCTAACAGATCGGAACATGAAATGCCCTCCTAAATGTCAGCTGTTGTCACACAGTAGCTCCAACACTTTGAGCATTTTT
AAGGGAGTGGCCTCATTTCACTAGAGACAAATCTTTAAGAATAGTTCTAAAATTGGGCTTGTGATTTCCATTTCTGATGTCTCCAGATTGGCACCCCTTTCTAGTTCAATGCCTCACGAGATTTACCA
GGGGCATCCAAAGCAAACAATCCCAATCTTTCTATATAAAATGTATTCAAACAAACATCAAATAAATTTCTGGGATATTTAACTATA

hide sequence


Protein RefSeqs	XP_007985247	(Get FASTA)	NCBI Sequence Viewer
	XP_007985248	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000009490
	ENSCSAP00000009490.1

RefSeq Acc Id:	XP_007985247 ⟸ XM_007987056
- UniProtKB:	A0A0D9RLK1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007985248 ⟸ XM_007987057
- UniProtKB:	A0A0D9RLK1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000009490 ⟸ ENSCSAT00000011418

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000013324	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000011418.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.140	UniProtKB/TrEMBL
	3.30.70.1130	UniProtKB/TrEMBL
	Translation initiation factor 2, subunit 1, domain 2	UniProtKB/TrEMBL
InterPro	NA-bd_OB-fold	UniProtKB/TrEMBL
	S1_domain	UniProtKB/TrEMBL
	S1_IF2_alpha	UniProtKB/TrEMBL
	TIF2_asu_C	UniProtKB/TrEMBL
	TIF2_asu_middle_sf	UniProtKB/TrEMBL
	TIF_2_asu	UniProtKB/TrEMBL
KEGG Report	csab:103229205	UniProtKB/TrEMBL
NCBI Gene	EIF2S1	ENTREZGENE
PANTHER	EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1	UniProtKB/TrEMBL
	PTHR10602	UniProtKB/TrEMBL
Pfam	EIF_2_alpha	UniProtKB/TrEMBL
	PF00575	UniProtKB/TrEMBL
PROSITE	PS50126	UniProtKB/TrEMBL
SMART	SM00316	UniProtKB/TrEMBL
Superfamily-SCOP	SSF110993	UniProtKB/TrEMBL
	SSF116742	UniProtKB/TrEMBL
	SSF50249	UniProtKB/TrEMBL
UniProt	A0A0D9RLK1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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