Eif2s3 (eukaryotic translation initiation factor 2 subunit gamma) - Rat Genome Database

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Gene: Eif2s3 (eukaryotic translation initiation factor 2 subunit gamma) Rattus norvegicus
Analyze
Symbol: Eif2s3
Name: eukaryotic translation initiation factor 2 subunit gamma
RGD ID: 1561279
Description: Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 2 complex. Human ortholog(s) of this gene implicated in MEHMO syndrome. Orthologous to human EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma); PARTICIPATES IN translation initiation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; aconitine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: eIF-2-gamma; eIF-2-gamma X; Eif2g; Eif2s3x; Eukaryotic translation initiation factor 2 subunit 3; eukaryotic translation initiation factor 2 subunit 3, X-linked; eukaryotic translation initiation factor 2 subunit gamma, X-linked; eukaryotic translation initiation factor 2, subunit 3 gamma; eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked; PP42
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X58,916,513 - 58,939,923 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX58,917,490 - 58,940,686 (-)Ensembl
Rnor_6.0X63,268,106 - 63,291,125 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX63,268,037 - 63,292,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X63,861,008 - 63,884,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X81,542,853 - 81,566,259 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX59,352,186 - 59,375,591 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8780732   PMID:8889548   PMID:10900014   PMID:12426392   PMID:16289705   PMID:16854843   PMID:20458337   PMID:23063529   PMID:25468996  


Genomics

Comparative Map Data
Eif2s3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X58,916,513 - 58,939,923 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX58,917,490 - 58,940,686 (-)Ensembl
Rnor_6.0X63,268,106 - 63,291,125 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX63,268,037 - 63,292,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X63,861,008 - 63,884,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X81,542,853 - 81,566,259 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX59,352,186 - 59,375,591 (-)NCBICelera
Cytogenetic MapXq22NCBI
EIF2S3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X24,054,956 - 24,078,810 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX24,054,946 - 24,078,810 (+)EnsemblGRCh38hg38GRCh38
GRCh37X24,073,073 - 24,096,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X23,982,986 - 24,006,848 (+)NCBINCBI36hg18NCBI36
Build 34X23,832,721 - 23,855,743NCBI
CeleraX28,196,181 - 28,220,053 (+)NCBI
Cytogenetic MapXp22.11NCBI
HuRefX21,816,175 - 21,839,574 (+)NCBIHuRef
CHM1_1X24,104,271 - 24,128,153 (+)NCBICHM1_1
Eif2s3x
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X93,232,315 - 93,256,257 (-)NCBIGRCm39mm39
GRCm39 EnsemblX93,232,313 - 93,256,468 (-)Ensembl
GRCm38X94,188,709 - 94,212,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX94,188,707 - 94,212,862 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X91,434,048 - 91,457,990 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X90,441,428 - 90,465,370 (-)NCBImm8
CeleraX81,110,914 - 81,134,502 (-)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX41.52NCBI
Eif2s3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555094,437,044 - 4,457,819 (+)NCBIChiLan1.0ChiLan1.0
EIF2S3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X24,027,099 - 24,050,879 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX24,027,099 - 24,050,879 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X16,653,762 - 16,678,198 (+)NCBIMhudiblu_PPA_v0panPan3
EIF2S3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X19,662,132 - 19,680,223 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX19,650,343 - 19,680,221 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X19,617,765 - 19,635,846 (+)NCBI
ROS_Cfam_1.0 EnsemblX19,605,975 - 19,637,812 (+)Ensembl
UMICH_Zoey_3.1X19,656,521 - 19,674,614 (+)NCBI
UNSW_CanFamBas_1.0X19,689,972 - 19,708,341 (+)NCBI
UU_Cfam_GSD_1.0X19,746,165 - 19,764,509 (+)NCBI
Eif2s3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X12,622,024 - 12,641,621 (+)NCBI
SpeTri2.0NW_004936624516,206 - 535,749 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF2S3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X20,129,708 - 20,162,881 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X21,554,153 - 21,587,126 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF2S3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X22,523,330 - 22,549,827 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605624,404,897 - 24,429,467 (+)NCBIVero_WHO_p1.0
Eif2s3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624897424,144 - 445,698 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH17627  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X58,922,335 - 58,923,518 (+)MAPPERmRatBN7.2
Rnor_6.0X63,273,928 - 63,275,110NCBIRnor6.0
Rnor_5.0X63,866,830 - 63,868,012UniSTSRnor5.0
RGSC_v3.4X81,548,676 - 81,549,858UniSTSRGSC3.4
CeleraX59,358,008 - 59,359,190UniSTS
Cytogenetic MapXq31UniSTS
EIF2S3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X58,923,467 - 58,923,572 (+)MAPPERmRatBN7.2
Rnor_6.0X63,275,060 - 63,275,164NCBIRnor6.0
Rnor_5.0X63,867,962 - 63,868,066UniSTSRnor5.0
RGSC_v3.4X81,549,808 - 81,549,912UniSTSRGSC3.4
CeleraX59,359,140 - 59,359,244UniSTS
Cytogenetic MapXq31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X5704214165612192Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:93
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000058134
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 36 11 8
Low 1 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000081124   ⟹   ENSRNOP00000072851
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX58,938,675 - 58,940,686 (-)Ensembl
Rnor_6.0 EnsemblX63,288,363 - 63,292,092 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082421   ⟹   ENSRNOP00000074806
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX58,917,490 - 58,940,165 (-)Ensembl
Rnor_6.0 EnsemblX63,281,779 - 63,291,371 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092019   ⟹   ENSRNOP00000070817
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX58,917,490 - 58,939,913 (-)Ensembl
Rnor_6.0 EnsemblX63,268,037 - 63,291,107 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114488   ⟹   ENSRNOP00000087240
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX58,917,490 - 58,939,909 (-)Ensembl
RefSeq Acc Id: NM_001100542   ⟹   NP_001094012
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X58,916,513 - 58,939,923 (-)NCBI
Rnor_6.0X63,268,106 - 63,291,125 (-)NCBI
Rnor_5.0X63,861,008 - 63,884,027 (-)NCBI
RGSC_v3.4X81,542,853 - 81,566,259 (-)RGD
CeleraX59,352,186 - 59,375,591 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001094012 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91286 (Get FASTA)   NCBI Sequence Viewer  
  AAI66783 (Get FASTA)   NCBI Sequence Viewer  
  EDL96007 (Get FASTA)   NCBI Sequence Viewer  
  P81795 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001094012   ⟸   NM_001100542
- UniProtKB: P81795 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070817   ⟸   ENSRNOT00000092019
RefSeq Acc Id: ENSRNOP00000074806   ⟸   ENSRNOT00000082421
RefSeq Acc Id: ENSRNOP00000072851   ⟸   ENSRNOT00000081124
RefSeq Acc Id: ENSRNOP00000087240   ⟸   ENSRNOT00000114488
Protein Domains
tr-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P81795-F1-model_v2 AlphaFold P81795 1-472 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701840
Promoter ID:EPDNEW_R12364
Type:multiple initiation site
Name:Eif2s3_1
Description:eukaryotic translation initiation factor 2 subunit gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X63,291,120 - 63,291,180EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
X 63866899 63866900 C G snv SDLEF7/Barth (UDEL), LE/OrlBarth (UDEL), BDIX.Cg-Tal/NemOda (KyushuU), F344/NSlc (KyushuU), F344/DuCrlCrlj (KyushuU)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561279 AgrOrtholog
BioCyc Gene G2FUF-2247 BioCyc
Ensembl Genes ENSRNOG00000060793 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070817 UniProtKB/Swiss-Prot
  ENSRNOP00000072851 UniProtKB/TrEMBL
  ENSRNOP00000074806 UniProtKB/TrEMBL
  ENSRNOP00000087240 ENTREZGENE
Ensembl Transcript ENSRNOT00000081124 UniProtKB/TrEMBL
  ENSRNOT00000082421 UniProtKB/TrEMBL
  ENSRNOT00000092019 UniProtKB/Swiss-Prot
  ENSRNOT00000114488 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7304876 IMAGE-MGC_LOAD
  IMAGE:7935021 IMAGE-MGC_LOAD
  IMAGE:9098876 IMAGE-MGC_LOAD
InterPro EFTu-like_2 UniProtKB/Swiss-Prot
  eIF2g_dom_2 UniProtKB/Swiss-Prot
  eIF2g_GTP-bd UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIF2_gsu_C UniProtKB/Swiss-Prot
  Transl_B-barrel_sf UniProtKB/Swiss-Prot
  Transl_elong_EF1A/Init_IF2_C UniProtKB/Swiss-Prot
KEGG Report rno:299027 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109183 IMAGE-MGC_LOAD
  MGC:187904 IMAGE-MGC_LOAD
  MGC:188564 IMAGE-MGC_LOAD
NCBI Gene 299027 ENTREZGENE
Pfam eIF2_C UniProtKB/Swiss-Prot
  GTP_EFTU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/Swiss-Prot
PhenoGen Eif2s3 PhenoGen
PRINTS ELONGATNFCT UniProtKB/Swiss-Prot
PROSITE G_TR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot
  SSF50465 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MJB9_RAT UniProtKB/TrEMBL
  A0A1P0QU16_RAT UniProtKB/TrEMBL
  IF2G_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B0BN96 UniProtKB/Swiss-Prot
  B2RYH8 UniProtKB/Swiss-Prot
  Q5BJX8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-09 Eif2s3  eukaryotic translation initiation factor 2 subunit gamma  Eif2s3  eukaryotic translation initiation factor 2, subunit 3 gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-11 Eif2s3  eukaryotic translation initiation factor 2, subunit 3 gamma  Eif2s3x  eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Eif2s3x  eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked      Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 Eif2s3x  eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked      Symbol and Name status set to provisional 70820 PROVISIONAL