Tnc (tenascin C) - Rat Genome Database
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Gene: Tnc (tenascin C) Mus musculus
Analyze
Symbol: Tnc
Name: tenascin C
RGD ID: 1615156
MGI Page MGI
Description: Predicted to have fibronectin binding activity and syndecan binding activity. Involved in several processes, including neuromuscular junction development; peripheral nervous system axon regeneration; and prostate gland development. Localizes to basement membrane; interstitial matrix; and perisynaptic extracellular matrix. Is expressed in several structures, including alimentary system; brain; ovary; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; autosomal dominant nonsyndromic deafness 56; and pulmonary hypertension. Orthologous to human TNC (tenascin C); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI528729; C130033P17Rik; cytota; cytotactin; hexabrachion; Hxb; MGC144208; MGC144209; T; Ten; tenas; tenascin; tenascin-C; TN; TN-; TN-C
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39463,878,022 - 63,965,554 (-)NCBIGRCm39mm39
GRCm38463,959,785 - 64,047,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl463,959,785 - 64,047,015 (-)EnsemblGRCm38mm10GRCm38
MGSCv37463,620,819 - 63,681,760 (-)NCBIGRCm37mm9NCBIm37
MGSCv36463,446,149 - 63,507,087 (-)NCBImm8
Celera462,620,454 - 62,681,423 (-)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
11-deoxycorticosterone  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (EXP)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alachlor  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
belinostat  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (EXP)
bucladesine  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
butane-2,3-dione  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
carmustine  (ISO)
chloroprene  (EXP)
choline  (EXP)
chrysene  (EXP)
cisplatin  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
corticosterone  (ISO)
curcumin  (EXP)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
diazepam  (ISO)
diethyl malate  (EXP)
diisononyl phthalate  (ISO)
dioxygen  (EXP)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (EXP)
fenoldopam  (ISO)
fenvalerate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (ISO)
genistein  (EXP)
glycidol  (ISO)
hesperidin  (ISO)
ibuprofen  (ISO)
isobutanol  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lithium chloride  (ISO)
losartan  (ISO)
medroxyprogesterone acetate  (ISO)
megestrol acetate  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mifepristone  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalene  (EXP)
nickel atom  (EXP,ISO)
nickel sulfate  (EXP,ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentane-2,3-dione  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
progesterone  (ISO)
Ptaquiloside  (EXP)
quercetin  (ISO)
raloxifene  (ISO)
rofecoxib  (ISO)
rotenone  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
serpentine asbestos  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
spironolactone  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thapsigargin  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
tremolite asbestos  (EXP)
trichostatin A  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
XL147  (EXP)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Avivi-Green C, etal., Am J Respir Crit Care Med. 2006 Aug 15;174(4):420-7. Epub 2006 May 11.
2. Carey WA, etal., Am J Physiol Lung Cell Mol Physiol. 2010 Sep 10.
3. Correia-Pinto J, etal., Basic Res Cardiol. 2009 Sep;104(5):535-45. Epub 2009 Mar 14.
4. Deckner M, etal., Exp Neurol. 2000 Dec;166(2):350-62.
5. Dumur CI, etal., Exp Mol Pathol. 2010 Dec;89(3):227-35. Epub 2010 Sep 9.
6. Hisatomi K, etal., Intern Med. 2009;48(17):1501-7. Epub 2009 Sep 1.
7. Ihida-Stansbury K, etal., Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L694-702. Epub 2006 Jun 16.
8. Imanaka-Yoshida K, etal., Lab Invest. 2001 Jul;81(7):1015-24.
9. Kaarteenaho-Wiik R, etal., Histopathology. 2003 Mar;42(3):280-91.
10. Kaarteenaho-Wiik R, etal., J Histochem Cytochem. 2000 Sep;48(9):1257-68.
11. Kaarteenaho-Wiik R, etal., Lung. 1998;176(6):371-80.
12. Laitinen A, etal., Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1):951-8.
13. Matsuda A, etal., Hum Mol Genet. 2005 Oct 1;14(19):2779-86. Epub 2005 Aug 22.
14. Nakahara H, etal., Eur J Immunol. 2006 Dec;36(12):3334-45.
15. Nishimura T, etal., Histol Histopathol. 2008 Feb;23(2):157-66.
16. OMIM Disease Annotation Pipeline
17. Orsmark-Pietras C, etal., Hum Mol Genet. 2008 Jun 1;17(11):1673-82. Epub 2008 Feb 27.
18. Pipeline to import KEGG annotations from KEGG into RGD
19. RGD automated import pipeline
20. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. RGD automated import pipeline for gene-chemical interactions
22. Schermuly RT, etal., Am J Respir Crit Care Med. 2005 Aug 1;172(3):358-63. Epub 2005 May 5.
23. Schumann C, etal., Biomarkers. 2010 Sep;15(6):523-32.
24. Silacci M, etal., Protein Eng Des Sel. 2006 Oct;19(10):471-8. Epub 2006 Aug 22.
25. Sun G, etal., Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2003 May;17(5):279-80.
26. Suzuki H, etal., Neurol Res. 2010 Mar;32(2):179-84. Epub 2009 Jul 8.
27. Taki J, etal., J Nucl Med. 2010 Jul;51(7):1116-22. Epub 2010 Jun 16.
28. Turan Akay M and Arzu Kockaya E, Cell Biochem Funct. 2005 Nov-Dec;23(6):435-45.
29. Whitehead GS, etal., Immunogenetics. 2006 Oct;58(10):793-804. Epub 2006 Sep 26.
Additional References at PubMed
PMID:1379092   PMID:1383086   PMID:1703162   PMID:1717349   PMID:2440899   PMID:2451586   PMID:2461951   PMID:2479585   PMID:7506500   PMID:7508415   PMID:7509489   PMID:7511372  
PMID:7512897   PMID:7512972   PMID:7513764   PMID:7524681   PMID:7530141   PMID:7530144   PMID:7534342   PMID:7534412   PMID:7539436   PMID:7539482   PMID:7544698   PMID:7546737  
PMID:7680659   PMID:7687262   PMID:7694605   PMID:7774911   PMID:7774913   PMID:8049528   PMID:8088814   PMID:8391931   PMID:8480178   PMID:8543661   PMID:8549652   PMID:8559162  
PMID:8600304   PMID:8601035   PMID:8647898   PMID:8660327   PMID:8692862   PMID:8769660   PMID:8785583   PMID:8838309   PMID:8849669   PMID:8856503   PMID:8898217   PMID:8981244  
PMID:9013311   PMID:9016309   PMID:9050867   PMID:9070278   PMID:9074936   PMID:9104592   PMID:9154819   PMID:9183385   PMID:9184108   PMID:9303344   PMID:9321695   PMID:9348542  
PMID:9367432   PMID:9382869   PMID:9407997   PMID:9415431   PMID:9442046   PMID:9454855   PMID:9482226   PMID:9593587   PMID:9596652   PMID:9753681   PMID:9813102   PMID:9856459  
PMID:9856798   PMID:9882526   PMID:9915576   PMID:10090148   PMID:10101119   PMID:10102501   PMID:10189061   PMID:10208749   PMID:10235540   PMID:10337627   PMID:10349636   PMID:10358070  
PMID:10409496   PMID:10510172   PMID:10547346   PMID:10676879   PMID:10681390   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11169482   PMID:11217851   PMID:11239431   PMID:11285276  
PMID:11347655   PMID:11436985   PMID:11486035   PMID:11493565   PMID:11767049   PMID:11829488   PMID:12009782   PMID:12056833   PMID:12106360   PMID:12177213   PMID:12359159   PMID:12466851  
PMID:12477932   PMID:12619136   PMID:12672030   PMID:12700241   PMID:12823230   PMID:12904321   PMID:12950088   PMID:14618612   PMID:14691545   PMID:14709716   PMID:14758483   PMID:15031101  
PMID:15084498   PMID:15117820   PMID:15162503   PMID:15162516   PMID:15226258   PMID:15305294   PMID:15336554   PMID:15355320   PMID:15483051   PMID:15537675   PMID:15548197   PMID:15592854  
PMID:15627506   PMID:15664401   PMID:15694392   PMID:15694413   PMID:15760903   PMID:15843414   PMID:15878328   PMID:15902305   PMID:15972953   PMID:16141072   PMID:16141073   PMID:16262627  
PMID:16262655   PMID:16420439   PMID:16452087   PMID:16452166   PMID:16458080   PMID:16461331   PMID:16518820   PMID:16537572   PMID:16553788   PMID:16602821   PMID:16699260   PMID:16730455  
PMID:16809539   PMID:16944957   PMID:16962305   PMID:17114649   PMID:17121418   PMID:17264084   PMID:17336282   PMID:17350578   PMID:17708357   PMID:17708541   PMID:17722031   PMID:17901052  
PMID:18083924   PMID:18094237   PMID:18243104   PMID:18269918   PMID:18287559   PMID:18489816   PMID:18570250   PMID:18617690   PMID:18651661   PMID:18667463   PMID:18757758   PMID:18802027  
PMID:18950615   PMID:18957871   PMID:19020026   PMID:19217425   PMID:19280660   PMID:19287959   PMID:19304887   PMID:19373938   PMID:19394429   PMID:19419974   PMID:19459213   PMID:19561617  
PMID:19633172   PMID:19641104   PMID:19686679   PMID:19690384   PMID:19793892   PMID:19885556   PMID:19887451   PMID:19961580   PMID:19998061   PMID:20059955   PMID:20081106   PMID:20498044  
PMID:20606643   PMID:20610746   PMID:20651280   PMID:20664686   PMID:20689858   PMID:20844127   PMID:20855890   PMID:21067603   PMID:21087965   PMID:21150899   PMID:21205293   PMID:21267068  
PMID:21300867   PMID:21308776   PMID:21335239   PMID:21354146   PMID:21513708   PMID:21677750   PMID:21705668   PMID:21750040   PMID:21751239   PMID:21858105   PMID:21898491   PMID:21911392  
PMID:21939397   PMID:21951663   PMID:22071102   PMID:22115758   PMID:22159717   PMID:22300502   PMID:22473292   PMID:22536403   PMID:22553313   PMID:22682244   PMID:22688677   PMID:22691363  
PMID:22711842   PMID:22808246   PMID:22851489   PMID:22972626   PMID:22998872   PMID:23034629   PMID:23041440   PMID:23042739   PMID:23055981   PMID:23084751   PMID:23178882   PMID:23207449  
PMID:23313574   PMID:23433402   PMID:23458899   PMID:23624942   PMID:23637166   PMID:23650387   PMID:23658023   PMID:23673309   PMID:23762363   PMID:23882691   PMID:23884445   PMID:24006456  
PMID:24012369   PMID:24084079   PMID:24101721   PMID:24139798   PMID:24154525   PMID:24154528   PMID:24229643   PMID:24244568   PMID:24260306   PMID:24260575   PMID:24291458   PMID:24431450  
PMID:24514259   PMID:24785493   PMID:24808173   PMID:24952961   PMID:24983448   PMID:25192051   PMID:25196097   PMID:25376187   PMID:25578971   PMID:25715693   PMID:25803581   PMID:26100917  
PMID:26116661   PMID:26371318   PMID:26438731   PMID:26473781   PMID:26529256   PMID:26764350   PMID:26952977   PMID:26984772   PMID:27089885   PMID:27180663   PMID:27256716   PMID:27398409  
PMID:27527664   PMID:27653694   PMID:27668890   PMID:27806288   PMID:27974153   PMID:28071719   PMID:28202523   PMID:28218627   PMID:28244007   PMID:28438606   PMID:28438836   PMID:28489004  
PMID:28512860   PMID:28535371   PMID:28539333   PMID:28549651   PMID:28652369   PMID:28714032   PMID:28746404   PMID:28807903   PMID:28857429   PMID:28874093   PMID:28959031   PMID:28984873  
PMID:29136112   PMID:29283973   PMID:29329412   PMID:29357412   PMID:29367009   PMID:29449623   PMID:29546590   PMID:29705244   PMID:29768404   PMID:29899142   PMID:30021842   PMID:30045859  
PMID:30179592   PMID:30295707   PMID:30358115   PMID:30409456   PMID:30455179   PMID:30504126   PMID:30629639   PMID:30737693   PMID:30980466   PMID:31169312   PMID:31195598   PMID:31271872  
PMID:31288084   PMID:31289197   PMID:31408364   PMID:31474744   PMID:31558805   PMID:31924792   PMID:32066496   PMID:32238932   PMID:32325033   PMID:32398354   PMID:32581705   PMID:32581832  
PMID:32586976   PMID:32591430   PMID:32634398   PMID:32845719   PMID:33077835  


Genomics

Comparative Map Data
Tnc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39463,878,022 - 63,965,554 (-)NCBIGRCm39mm39
GRCm38463,959,785 - 64,047,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl463,959,785 - 64,047,015 (-)EnsemblGRCm38mm10GRCm38
MGSCv37463,620,819 - 63,681,760 (-)NCBIGRCm37mm9NCBIm37
MGSCv36463,446,149 - 63,507,087 (-)NCBImm8
Celera462,620,454 - 62,681,423 (-)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.06NCBI
TNC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9115,019,575 - 115,118,257 (-)EnsemblGRCh38hg38GRCh38
GRCh389115,019,575 - 115,118,244 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379117,781,854 - 117,880,436 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh379117,781,854 - 117,880,536 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369116,822,626 - 116,920,307 (-)NCBINCBI36hg18NCBI36
Build 349114,862,366 - 114,959,993NCBI
Celera988,430,273 - 88,527,747 (-)NCBI
Cytogenetic Map9q33.1NCBI
HuRef987,386,539 - 87,484,951 (-)NCBIHuRef
CHM1_19117,928,574 - 118,027,020 (-)NCBICHM1_1
Tnc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2577,375,851 - 77,460,712 (-)NCBI
Rnor_6.0 Ensembl579,789,671 - 79,874,671 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0579,789,686 - 79,874,555 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0583,890,952 - 83,950,462 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera576,306,295 - 76,365,869 (-)NCBICelera
Cytogenetic Map5q24NCBI
Tnc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541912,569,547 - 12,662,958 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541912,569,620 - 12,662,897 (+)NCBIChiLan1.0ChiLan1.0
LOC100977568
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19114,486,778 - 114,584,297 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9114,486,778 - 114,584,299 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0986,125,672 - 86,222,804 (-)NCBIMhudiblu_PPA_v0panPan3
TNC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1169,077,535 - 69,170,281 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11169,077,532 - 69,169,673 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tnc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364874,172,263 - 4,256,780 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1255,532,449 - 255,630,377 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11255,533,235 - 255,630,381 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21286,732,751 - 286,813,962 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1q21.1-q21.3NCBI
TNC
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11224,457,616 - 24,556,194 (+)NCBI
ChlSab1.1 Ensembl1224,457,738 - 24,556,451 (+)Ensembl
Tnc
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476020,044,900 - 20,137,260 (+)NCBI

Position Markers
BB343343  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38463,998,383 - 63,998,470UniSTSGRCm38
MGSCv37463,659,417 - 63,659,504UniSTSGRCm37
Celera462,659,054 - 62,659,141UniSTS
Cytogenetic Map4C1UniSTS
cM Map432.2UniSTS
Whitehead/MRC_RH1127.45UniSTS
RH130033  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38463,959,897 - 63,960,079UniSTSGRCm38
MGSCv37463,620,931 - 63,621,113UniSTSGRCm37
Celera462,620,566 - 62,620,748UniSTS
Cytogenetic Map4C1UniSTS
cM Map432.2UniSTS
AI528729  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38463,960,014 - 63,960,124UniSTSGRCm38
MGSCv37463,621,048 - 63,621,158UniSTSGRCm37
Celera462,620,683 - 62,620,793UniSTS
Cytogenetic Map4C1UniSTS
cM Map432.2UniSTS
Whitehead/MRC_RH4980.74UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
cM Map432.2UniSTS
cM Map432.2UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
cM Map432.2UniSTS
Tnc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117215009Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261689063979Mouse
1357645Lvrq9_mliver weight QTL 9 (mouse)Not determined41789261689063979Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261689063979Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261689063979Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000129100000Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108500000Mouse
1301941Mmtg1_mmodifier of mammary tumor growth 1 (mouse)Not determined44565844283180920Mouse
1558948Ath8_matherosclerosis 8 (mouse)Not determined445658442105299798Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138615442Mouse
1300966Pabr2_mplasma apolipoprotein B (human) regulator 2 (mouse)Not determined446332646105944663Mouse
10043880Adip23_madiposity 23 (mouse)Not determined44636529480365441Mouse
12879977Bod2_mbone length and organs 2 (mouse)44636529480365441Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123233418Mouse
10449022Aanq1_maristolochic acid nephrotoxicity QTL 1 (mouse)44668558980685589Mouse
11532688Mh_mmodifier of hemostasis (mouse)44838653882386538Mouse
25314308Mlh1fc1_mMLH1 foci count 1 (mouse)44850000077000000Mouse
1301213Lgth3_mbody length 3 (mouse)Not determined45018202584182171Mouse
1301995Lprm1_mlymphoproliferation modifier 1 (mouse)Not determined45018202584182171Mouse
13207572Spir2_mStreptococcus pneumoniae infection resistance 2 (mouse)45068279588592400Mouse
1301033Abbp2_mA/J and C57BL/6 blood pressure 2 (mouse)Not determined45355083993875068Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124161387Mouse
26884434Zlq1_mzygomatic length QTL 1, 5 week (mouse)453700000103400000Mouse
13524838Hbasrq1a_mhabituation of the acoustic startle response QTL 1a (mouse)45455335288553352Mouse
13524841Hbasrq1_mhabituation of the acoustic startle response QTL 1 (mouse)45455335288553352Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000129100000Mouse
27095934Ulnl2_mulna length 2, 5 week (mouse)45770000094900000Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155600000Mouse
10043964Obq26_mobesity QTL 26 (mouse)Not determined45912901493129014Mouse
1301190Cd4ts2_mCD4 T cell subset 2 (mouse)Not determined46022704094227187Mouse
1357507Synch2_msynechia 2 (mouse)Not determined46022704094227187Mouse
1357443Lhyp_mlung hyperpermeability (mouse)Not determined46049801266846581Mouse
25394561Skmw53_mskeletal muscle weight 53, TA (mouse)46222005669919794Mouse
12738417Lfibq13_mliver fibrosis QTL 13 (mouse)46368558965386538Mouse
1357870Pfat1_mpredicted fat percentage 1 (mouse)Not determined46370128997701448Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1351
Count of miRNA genes:410
Interacting mature miRNAs:470
Transcripts:ENSMUST00000030056, ENSMUST00000107371, ENSMUST00000107372, ENSMUST00000107377
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001369211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001369212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001369213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001369214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006537776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ236880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU614130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY300535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB521403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD352874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF531007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN664449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN692948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX568603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D90343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X56304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X80281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000030056   ⟹   ENSMUSP00000030056
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl463,959,785 - 64,020,725 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107371   ⟹   ENSMUSP00000102994
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl464,012,669 - 64,020,725 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107372   ⟹   ENSMUSP00000102995
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl463,959,785 - 64,020,725 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107377   ⟹   ENSMUSP00000103000
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl463,959,785 - 64,047,015 (-)Ensembl
RefSeq Acc Id: NM_001369211   ⟹   NP_001356140
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39463,878,026 - 63,965,173 (-)NCBI
GRCm38463,959,789 - 64,046,936 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001369212   ⟹   NP_001356141
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39463,878,026 - 63,965,173 (-)NCBI
GRCm38463,959,789 - 64,046,936 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001369213   ⟹   NP_001356142
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39463,878,026 - 63,965,173 (-)NCBI
GRCm38463,959,789 - 64,046,936 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001369214   ⟹   NP_001356143
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39463,878,026 - 63,965,173 (-)NCBI
GRCm38463,959,789 - 64,046,936 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011607   ⟹   NP_035737
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39463,878,022 - 63,965,252 (-)NCBI
GRCm38463,959,785 - 64,047,015 (-)ENTREZGENE
MGSCv37463,620,819 - 63,681,760 (-)RGD
Celera462,620,454 - 62,707,711 (-)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006537776   ⟹   XP_006537839
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39463,878,025 - 63,965,554 (-)NCBI
GRCm38463,959,788 - 64,047,010 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035737   ⟸   NM_011607
- Peptide Label: isoform 2 precursor
- UniProtKB: Q80YX1 (UniProtKB/Swiss-Prot),   Q148T5 (UniProtKB/TrEMBL),   Q8C9Z1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006537839   ⟸   XM_006537776
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001356142   ⟸   NM_001369213
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001356143   ⟸   NM_001369214
- Peptide Label: isoform 5 precursor
RefSeq Acc Id: NP_001356141   ⟸   NM_001369212
- Peptide Label: isoform 3 precursor
RefSeq Acc Id: NP_001356140   ⟸   NM_001369211
- Peptide Label: isoform 1 precursor
RefSeq Acc Id: ENSMUSP00000102995   ⟸   ENSMUST00000107372
RefSeq Acc Id: ENSMUSP00000102994   ⟸   ENSMUST00000107371
RefSeq Acc Id: ENSMUSP00000103000   ⟸   ENSMUST00000107377
RefSeq Acc Id: ENSMUSP00000030056   ⟸   ENSMUST00000030056
Promoters
RGD ID:6836549
Promoter ID:MM_KWN:38023
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:ENSMUST00000107371,   ENSMUST00000107372,   NM_011607,   UC008THF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36463,681,381 - 63,682,332 (-)MPROMDB
RGD ID:6883670
Promoter ID:EPDNEW_M5286
Type:multiple initiation site
Name:Tnc_1
Description:Mus musculus tenascin C , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38464,046,932 - 64,046,992EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:101922 AgrOrtholog
Ensembl Genes ENSMUSG00000028364 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000030056 UniProtKB/Swiss-Prot
  ENSMUSP00000102994 UniProtKB/TrEMBL
  ENSMUSP00000102995 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000103000 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030056 UniProtKB/Swiss-Prot
  ENSMUST00000107371 UniProtKB/TrEMBL
  ENSMUST00000107372 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000107377 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_extracell UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Tenascin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:101922 ENTREZGENE
NCBI Gene 21923 ENTREZGENE
PANTHER PTHR46708:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Tenascin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tnc PhenoGen
PROSITE EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FIBRINOGEN_C_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56496 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q148T4_MOUSE UniProtKB/TrEMBL
  Q148T5 ENTREZGENE, UniProtKB/TrEMBL
  Q80YX0_MOUSE UniProtKB/TrEMBL
  Q80YX1 ENTREZGENE
  Q8C9Z1 ENTREZGENE, UniProtKB/TrEMBL
  Q9WUU4_MOUSE UniProtKB/TrEMBL
  TENA_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q64706 UniProtKB/Swiss-Prot
  Q80YX2 UniProtKB/Swiss-Prot