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Gene: Tnc (tenascin C) Mus musculus
Symbol: Tnc
Name: tenascin C
Description: Predicted to have fibronectin binding activity and syndecan binding activity. Involved in several processes, including neuromuscular junction development; peripheral nervous system axon regeneration; and prostate gland development. Localizes to the basement membrane; interstitial matrix; and perisynaptic extracellular matrix. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; autosomal dominant nonsyndromic deafness 56; and pulmonary hypertension. Is expressed in several structures, including alimentary system; brain; ovary; sensory organ; and skeleton. Orthologous to human TNC (tenascin C); PARTICIPATES IN cell-extracellular matrix signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 2,6-di-tert-butyl-4-methylphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI528729; C130033P17Rik; cytotactin; hexabrachion; Hxb; MGC144208; MGC144209; Ten; tenascin; tenascin-C; TN; TN-C
Homo sapiens (human) : TNC (tenascin C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnc (tenascin C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnc (tenascin C)
Pan paniscus (bonobo/pygmy chimpanzee) : TNC (tenascin C)
Canis lupus familiaris (dog) : TNC (tenascin C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnc (tenascin C)
Sus scrofa (pig) : TNC (tenascin C)
Chlorocebus sabaeus (green monkey) : TNC (tenascin C)
Heterocephalus glaber (naked mole-rat) : Tnc (tenascin C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl463,959,785 - 64,047,015 (-)Ensembl
GRCm38463,959,785 - 64,047,015 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37463,620,819 - 63,681,760 (-)NCBIGRCm37mm9NCBIm37
MGSCv36463,446,149 - 63,507,087 (-)NCBImm8
Celera462,620,454 - 62,707,711 (-)NCBICelera
Cytogenetic Map4 C1NCBI
cM Map434.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tnc
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615156
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.