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Gene: Ncf2 (neutrophil cytosolic factor 2) Mus musculus
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Symbol: Ncf2
Name: neutrophil cytosolic factor 2
Description: Exhibits Rac GTPase binding activity. Contributes to superoxide-generating NADPH oxidase activity. Involved in superoxide anion generation. Localizes to acrosomal vesicle. Is expressed in several structures, including hemolymphoid system; limb; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal recessive chronic granulomatous disease cytochrome b-positive type II. Orthologous to human NCF2 (neutrophil cytosolic factor 2); PARTICIPATES IN Leishmaniasis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 67 kDa neutrophil oxidase factor; NADPH oxidase activator 2; NADPH oxidase subunit (67 kD); NADPH oxidase subunit (67kDa); Ncf-2; neutrophil cytosol factor 2; neutrophil NADPH oxidase factor 2; NOXA2; p67-phox; p67phox
Orthologs:
Homo sapiens (human) : NCF2 (neutrophil cytosolic factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ncf2 (neutrophil cytosolic factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncf2 (neutrophil cytosolic factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCF2 (neutrophil cytosolic factor 2)
Canis lupus familiaris (dog) : NCF2 (neutrophil cytosolic factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncf2 (neutrophil cytosolic factor 2)
Sus scrofa (pig) : NCF2 (neutrophil cytosolic factor 2)
Chlorocebus sabaeus (African green monkey) : NCF2 (neutrophil cytosolic factor 2)
Heterocephalus glaber (naked mole-rat) : Ncf2 (neutrophil cytosolic factor 2)
more info ...
Related Pseudogenes: Ncf2-rs  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1152,800,194 - 152,836,991 (+)EnsemblGRCm38mm10GRCm38
GRCm381152,800,153 - 152,836,990 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371154,655,020 - 154,684,120 (+)NCBIGRCm37mm9NCBIm37
MGSCv361154,570,108 - 154,599,208 (+)NCBImm8
Celera1155,229,233 - 155,258,077 (+)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ncf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319761
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.