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Gene: Ncf2 (neutrophil cytosolic factor 2) Mus musculus
Symbol: Ncf2
Name: neutrophil cytosolic factor 2
Description: Exhibits Rac GTPase binding activity. Contributes to superoxide-generating NADPH oxidase activity. Involved in superoxide anion generation. Localizes to acrosomal vesicle. Is expressed in several structures, including hemolymphoid system; limb; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal recessive chronic granulomatous disease cytochrome b-positive type II. Orthologous to human NCF2 (neutrophil cytosolic factor 2); PARTICIPATES IN Leishmaniasis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 67 kDa neutrophil oxidase factor; NADPH oxidase activator 2; NADPH oxidase subunit (67 kD); NADPH oxidase subunit (67kDa); Ncf-2; neutrophil cytosol factor 2; neutrophil NADPH oxidase factor 2; NOXA2; p67-phox; p67phox
Homo sapiens (human) : NCF2 (neutrophil cytosolic factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ncf2 (neutrophil cytosolic factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncf2 (neutrophil cytosolic factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCF2 (neutrophil cytosolic factor 2)
Canis lupus familiaris (dog) : NCF2 (neutrophil cytosolic factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncf2 (neutrophil cytosolic factor 2)
Sus scrofa (pig) : NCF2 (neutrophil cytosolic factor 2)
Chlorocebus sabaeus (African green monkey) : NCF2 (neutrophil cytosolic factor 2)
Heterocephalus glaber (naked mole-rat) : Ncf2 (neutrophil cytosolic factor 2)
more info ...
Related Pseudogenes: Ncf2-rs  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1152,800,194 - 152,836,991 (+)EnsemblGRCm38mm10GRCm38
GRCm381152,800,153 - 152,836,990 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371154,655,020 - 154,684,120 (+)NCBIGRCm37mm9NCBIm37
MGSCv361154,570,108 - 154,599,208 (+)NCBImm8
Celera1155,229,233 - 155,258,077 (+)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ncf2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319761
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.