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Gene: Csf2 (colony stimulating factor 2 (granulocyte-macrophage)) Mus musculus
Symbol: Csf2
Name: colony stimulating factor 2 (granulocyte-macrophage)
Description: Exhibits cytokine activity. Involved in several processes, including embryonic placenta development; myeloid leukocyte differentiation; and positive regulation of cell population proliferation. Localizes to the extracellular space. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Is expressed in several structures, including genitourinary system; hemolymphoid system; labyrinthine zone; liver; and lung. Orthologous to human CSF2 (colony stimulating factor 2); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; syndecan signaling pathway; INTERACTS WITH 1,4-benzoquinone; 1,4-phenylenediamine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: colony-stimulating factor; CSF; Csfgm; Gm-CSf; GMCSF; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC151255; MGC151257; MGI-IGM; put. GM-CSF
Homo sapiens (human) : CSF2 (colony stimulating factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Csf2 (colony stimulating factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf2 (colony stimulating factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF2 (colony stimulating factor 2)
Canis lupus familiaris (dog) : CSF2 (colony stimulating factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf2 (colony stimulating factor 2)
Sus scrofa (pig) : CSF2 (colony stimulating factor 2)
Chlorocebus sabaeus (African green monkey) : CSF2 (colony stimulating factor 2)
Heterocephalus glaber (naked mole-rat) : Csf2 (colony stimulating factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1154,247,271 - 54,249,667 (-)Ensembl
GRCm381154,247,270 - 54,249,899 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371154,060,772 - 54,063,401 (-)NCBIGRCm37mm9NCBIm37
MGSCv361154,090,687 - 54,093,065 (-)NCBImm8
Celera1158,835,805 - 58,838,455 (-)NCBICelera
Cytogenetic Map11 B1.3NCBI
cM Map1132.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Csf2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551314
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.