Tpo (thyroid peroxidase) - Rat Genome Database

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Gene: Tpo (thyroid peroxidase) Mus musculus
Analyze
Symbol: Tpo
Name: thyroid peroxidase
RGD ID: 733214
MGI Page MGI
Description: Predicted to enable peroxidase activity. Predicted to be involved in embryonic hemopoiesis. Predicted to act upstream of or within hormone biosynthetic process and hydrogen peroxide catabolic process. Located in mitochondrion. Is expressed in left lung; right lung; thyroid gland; and thyroid gland lobe. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in congenital hypothyroidism; glomerulonephritis; and thyroid dyshormonogenesis 2A. Orthologous to human TPO (thyroid peroxidase).
Type: protein-coding
RefSeq Status: REVIEWED
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391230,104,658 - 30,182,983 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1230,104,658 - 30,182,623 (-)EnsemblGRCm39 Ensembl
GRCm381230,054,659 - 30,132,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1230,054,659 - 30,132,624 (-)EnsemblGRCm38mm10GRCm38
MGSCv371230,739,526 - 30,817,474 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361230,640,713 - 30,718,661 (-)NCBIMGSCv36mm8
Celera1231,518,105 - 31,587,543 (-)NCBICelera
Cytogenetic Map12A2NCBI
cM Map1213.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-naringenin  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,4-Dihydroxybenzophenone  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-Aminophenyl ether  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
bathocuproine disulfonic acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
benzophenone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (ISO)
Butylparaben  (ISO)
C60 fullerene  (ISO)
carbaryl  (ISO)
CGP 52608  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
daidzein  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
doxorubicin  (ISO)
efavirenz  (ISO)
Ethylenethiourea  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glutathione  (ISO)
glyphosate  (ISO)
iodide salt  (ISO)
isoniazide  (ISO)
isoprenaline  (ISO)
mancozeb  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
minocycline  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (ISO)
N-acetyl-L-cysteine  (ISO)
N-Vinyl-2-pyrrolidone  (ISO)
nevirapine  (ISO)
nitrogen dioxide  (ISO)
o-anisidine  (ISO)
oxymetholone  (ISO)
ozone  (ISO)
perchlorate  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
potassium iodide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
pyridine-2,3-diol  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
resorcinol  (ISO)
resveratrol  (ISO)
salicylhydroxamic acid  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
sodium azide  (ISO)
sodium iodide  (ISO)
sodium nitrate  (ISO)
sodium perchlorate  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
thyroxine  (ISO)
triclocarban  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (EXP,ISO)
vemurafenib  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zineb  (ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal coat/ hair morphology  (IEA)
abnormal cochlea morphology  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal femur morphology  (IAGP)
abnormal forelimb morphology  (IEA)
abnormal gait  (IEA)
abnormal hindlimb morphology  (IEA)
abnormal startle reflex  (IEA)
abnormal tectorial membrane morphology  (IAGP)
abnormal thyroid follicle morphology  (IAGP)
abnormal thyroid follicular cell morphology  (IAGP)
abnormal thyroid gland development  (IAGP)
abnormal thyroid gland morphology  (IAGP)
abnormal thyroid gland physiology  (IAGP)
decreased activity of thyroid gland  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased circulating glucose level  (IEA)
decreased erythrocyte cell number  (IAGP)
decreased exploration in new environment  (IEA)
decreased hematocrit  (IAGP)
decreased spleen weight  (IEA)
delayed inner ear development  (IAGP)
disproportionate dwarf  (IAGP)
enlarged thyroid gland  (IAGP)
exophthalmos  (IAGP)
impaired righting response  (IEA)
improved glucose tolerance  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased circulating cholesterol level  (IEA)
increased circulating creatinine level  (IEA)
increased circulating iron level  (IEA)
increased circulating thyroid-stimulating hormone level  (IAGP)
increased mean platelet volume  (IEA)
increased or absent threshold for auditory brainstem response  (IAGP)
limb grasping  (IEA)
premature death  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
prominent forehead  (IAGP)
proportional dwarf  (IAGP)
small spleen  (IAGP)
small thyroid gland  (IAGP)
tremors  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Identification of five novel inactivating mutations in the human thyroid peroxidase gene by denaturing gradient gel electrophoresis. Bikker H, etal., Hum Mutat. 1995;6(1):9-16.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Pretransplant positivity for circulating thyroid antibodies and graft survival in patients undergoing kidney transplant. Rotondi M, etal., Horm Res. 2009;71(6):324-30. doi: 10.1159/000223416. Epub 2009 Jun 6.
12. Increased prevalence of thyroid peroxidase antibodies (TPO-Ab) in women with glomerulonephritis. Westman KW, etal., Nephrol Dial Transplant. 1993;8(5):402-6.
Additional References at PubMed
PMID:1354596   PMID:2691880   PMID:4346605   PMID:7759120   PMID:7916704   PMID:8027236   PMID:8088780   PMID:8088836   PMID:8390965   PMID:8630490   PMID:9590297   PMID:10349636  
PMID:10440727   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11687289   PMID:12432093   PMID:12477932   PMID:12766619   PMID:12815622   PMID:14651853   PMID:14681479   PMID:15452344  
PMID:15927672   PMID:16141072   PMID:16141073   PMID:16150900   PMID:16762971   PMID:20573721   PMID:21149592   PMID:21224471   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22132122  
PMID:23563309   PMID:23707896   PMID:24265449   PMID:24297261   PMID:25127920   PMID:28067429   PMID:28898113   PMID:30446499   PMID:35294228   PMID:37964961  


Genomics

Comparative Map Data
Tpo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391230,104,658 - 30,182,983 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1230,104,658 - 30,182,623 (-)EnsemblGRCm39 Ensembl
GRCm381230,054,659 - 30,132,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1230,054,659 - 30,132,624 (-)EnsemblGRCm38mm10GRCm38
MGSCv371230,739,526 - 30,817,474 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361230,640,713 - 30,718,661 (-)NCBIMGSCv36mm8
Celera1231,518,105 - 31,587,543 (-)NCBICelera
Cytogenetic Map12A2NCBI
cM Map1213.0NCBI
TPO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3821,374,047 - 1,543,673 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl21,374,066 - 1,543,711 (+)EnsemblGRCh38hg38GRCh38
GRCh3721,417,235 - 1,547,445 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3621,396,242 - 1,525,502 (+)NCBINCBI36Build 36hg18NCBI36
Build 3421,396,241 - 1,525,502NCBI
Celera21,466,953 - 1,592,423 (+)NCBICelera
Cytogenetic Map2p25.3NCBI
HuRef21,408,795 - 1,531,941 (+)NCBIHuRef
CHM1_121,409,624 - 1,546,343 (+)NCBICHM1_1
T2T-CHM13v2.021,414,928 - 1,549,090 (+)NCBIT2T-CHM13v2.0
Tpo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8652,425,998 - 52,495,793 (-)NCBIGRCr8
mRatBN7.2646,698,402 - 46,768,199 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl646,698,414 - 46,768,199 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx647,003,424 - 47,073,172 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0647,318,282 - 47,388,031 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0646,753,566 - 46,823,319 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0649,020,918 - 49,089,855 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl649,021,044 - 49,089,855 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0657,702,091 - 57,770,914 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4647,954,848 - 48,025,740 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1647,957,973 - 48,028,866 (-)NCBI
Celera645,906,515 - 45,971,940 (-)NCBICelera
RH 3.4 Map6299.2RGD
Cytogenetic Map6q16NCBI
Tpo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955487494,746 - 529,416 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955487485,029 - 530,287 (-)NCBIChiLan1.0ChiLan1.0
TPO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212125,044,194 - 125,171,557 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A125,048,171 - 125,175,534 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A1,364,083 - 1,491,284 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A1,334,608 - 1,493,308 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A1,335,556 - 1,493,055 (+)Ensemblpanpan1.1panPan2
TPO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.117773,790 - 810,044 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl17773,790 - 810,043 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha17760,899 - 796,526 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.017830,903 - 866,744 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl17831,063 - 866,737 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.117755,185 - 790,848 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.017775,417 - 811,064 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.017775,279 - 810,948 (+)NCBIUU_Cfam_GSD_1.0
Tpo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629245,635,285 - 45,680,483 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936532390,327 - 429,386 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936532391,181 - 435,132 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3132,384,583 - 132,409,208 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13132,384,677 - 132,409,750 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23141,795,655 - 141,820,693 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TPO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114106,148,214 - 106,255,442 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14106,146,946 - 106,255,298 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660455,734,964 - 5,848,587 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpo
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248461,934,469 - 1,961,291 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248461,934,084 - 1,962,637 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tpo
2993 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:456
Count of miRNA genes:343
Interacting mature miRNAs:387
Transcripts:ENSMUST00000021005, ENSMUST00000140875, ENSMUST00000155263
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401249Bglu15_mblood glucose level 15 (mouse)Not determined121062064244620809Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132758756Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133430339Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12805000040049999Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
1300870Ath18_matherosclerosis 18 (mouse)Not determined121825996652260067Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1234013434340302Mouse
13524843Ppiq8_mprepulse inhibition QTL 8 (mouse)121104319450945796Mouse
4141516slwr_mslowlearner (mouse)Not determined1239247546392614Mouse
10043977Obq34_mobesity QTL 34 (mouse)Not determined121514733149147331Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12772315841723301Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130433078Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
26884413Bzwq9_mbi-zygomatic width QTL 9, 10 week (mouse)121615000147746783Mouse
1301723Fcsa7_mfemoral cross-sectional area 7 (mouse)Not determined12949100443491112Mouse
15039339Nmrs29_mNAFLD-associated magnetic resonance shift 29 (mouse)121782585251825852Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121973983353739833Mouse
1301037Cd4ts5_mCD4 T cell subset 5 (mouse)Not determined12835244442352581Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
14746972Manh72_mmandible shape 72 (mouse)121061528144615281Mouse
10043848Hdlq90_mHDL QTL 90 (mouse)Not determined121783993951840081Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse

Markers in Region
M-07403  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381230,054,751 - 30,054,904UniSTSGRCm38
MGSCv371230,739,616 - 30,739,769UniSTSGRCm37
Celera1231,518,195 - 31,518,348UniSTS
Cytogenetic Map12CUniSTS
cM Map1215.0UniSTS
Whitehead/MRC_RH12289.28UniSTS
Tpo  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12CUniSTS
cM Map1215.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003950045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_872405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC165078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LXEJ02007438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000021005   ⟹   ENSMUSP00000021005
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1230,104,658 - 30,182,623 (-)Ensembl
GRCm38.p6 Ensembl1230,054,659 - 30,132,624 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140875
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1230,142,123 - 30,144,998 (-)Ensembl
GRCm38.p6 Ensembl1230,092,124 - 30,094,999 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155263   ⟹   ENSMUSP00000133853
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1230,166,617 - 30,181,898 (-)Ensembl
GRCm38.p6 Ensembl1230,116,618 - 30,131,899 (-)Ensembl
RefSeq Acc Id: NM_009417   ⟹   NP_033443
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391230,104,660 - 30,182,623 (-)NCBI
GRCm381230,054,661 - 30,132,624 (-)NCBI
MGSCv371230,739,526 - 30,817,474 (-)RGD
Celera1231,518,105 - 31,587,543 (-)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011243856   ⟹   XP_011242158
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391230,107,284 - 30,182,983 (-)NCBI
GRCm381230,057,294 - 30,132,984 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003950045
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391230,104,658 - 30,182,983 (-)NCBI
GRCm381230,054,659 - 30,132,984 (-)NCBI
Sequence:
RefSeq Acc Id: XR_872405
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391230,107,284 - 30,182,983 (-)NCBI
GRCm381230,057,293 - 30,132,984 (-)NCBI
Sequence:
RefSeq Acc Id: NP_033443   ⟸   NM_009417
- Peptide Label: precursor
- UniProtKB: Q8C8B1 (UniProtKB/Swiss-Prot),   P35419 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242158   ⟸   XM_011243856
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000021005   ⟸   ENSMUST00000021005
RefSeq Acc Id: ENSMUSP00000133853   ⟸   ENSMUST00000155263
Protein Domains
EGF-like   Sushi

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35419-F1-model_v2 AlphaFold P35419 1-914 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98813 AgrOrtholog
Ensembl Genes ENSMUSG00000020673 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000021005 ENTREZGENE
  ENSMUST00000021005.15 UniProtKB/Swiss-Prot
  ENSMUST00000155263.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.640.10 UniProtKB/Swiss-Prot
  Complement Module, domain 1 UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
InterPro EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot
  Haem_peroxidase_animal UniProtKB/Swiss-Prot
  Haem_peroxidase_sf UniProtKB/Swiss-Prot
  Haem_peroxidase_sf_animal UniProtKB/Swiss-Prot
  Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot
  TPO UniProtKB/Swiss-Prot
KEGG Report mmu:22018 UniProtKB/Swiss-Prot
MGD MGI:98813 ENTREZGENE
NCBI Gene 22018 ENTREZGENE
PANTHER OXIDASE/PEROXIDASE UniProtKB/Swiss-Prot
  PTHR11475:SF60 UniProtKB/Swiss-Prot
Pfam An_peroxidase UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  Sushi UniProtKB/Swiss-Prot
PhenoGen Tpo PhenoGen
PRINTS ANPEROXIDASE UniProtKB/Swiss-Prot
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  PEROXIDASE_1 UniProtKB/Swiss-Prot
  PEROXIDASE_3 UniProtKB/Swiss-Prot
  SUSHI UniProtKB/Swiss-Prot
SMART CCP UniProtKB/Swiss-Prot
  EGF UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
  SSF48113 UniProtKB/Swiss-Prot
  SSF57535 UniProtKB/Swiss-Prot
UniProt G3UXW8_MOUSE UniProtKB/TrEMBL
  P35419 ENTREZGENE, UniProtKB/Swiss-Prot
  Q4FZJ9_MOUSE UniProtKB/TrEMBL
  Q8C8B1 ENTREZGENE
UniProt Secondary Q8C8B1 UniProtKB/Swiss-Prot