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Gene: Tpo (thyroid peroxidase) Mus musculus
Symbol: Tpo
Name: thyroid peroxidase
Description: Predicted to have peroxidase activity. Predicted to be involved in embryonic hemopoiesis. Localizes to the mitochondrion. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in congenital hypothyroidism and glomerulonephritis. Is expressed in left lung; right lung; thyroid gland; and thyroid gland lobe. Orthologous to human TPO (thyroid peroxidase).
Type: protein-coding
RefSeq Status: REVIEWED
Homo sapiens (human) : TPO (thyroid peroxidase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tpo (thyroid peroxidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tpo (thyroid peroxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : TPO (thyroid peroxidase)
Canis lupus familiaris (dog) : TPO (thyroid peroxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tpo (thyroid peroxidase)
Sus scrofa (pig) : TPO (thyroid peroxidase)
Chlorocebus sabaeus (green monkey) : TPO (thyroid peroxidase)
Heterocephalus glaber (naked mole-rat) : Tpo (thyroid peroxidase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1230,054,659 - 30,132,624 (-)Ensembl
GRCm381230,054,659 - 30,132,984 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371230,739,526 - 30,817,474 (-)NCBIGRCm37mm9NCBIm37
MGSCv361230,640,713 - 30,718,661 (-)NCBImm8
Celera1231,518,105 - 31,587,543 (-)NCBICelera
Cytogenetic Map12 A2NCBI
cM Map1213.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tpo
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733214
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.