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Gene: Nfatc3 (nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3) Mus musculus
Symbol: Nfatc3
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
Description: ENCODES a protein that exhibits chromatin binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; INVOLVED IN blood vessel remodeling; branching involved in blood vessel morphogenesis; calcineurin-NFAT signaling cascade; PARTICIPATES IN B cell receptor signaling pathway; T cell receptor signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH abnormal blood vessel morphology; abnormal cardiovascular system physiology; abnormal cellular respiration; ASSOCIATED WITH Left Ventricular Hypertrophy; Right Ventricular Hypertrophy; keratoconus (ortholog); FOUND IN cytoplasm; cytosol; nucleus; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C80703; D8Ertd281e; NF-AT4; NF-ATc3; NFAT4; NFATx; nuclear factor of activated T-cells, cytoplasmic 3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; T-cell transcription factor NFAT4
Homo sapiens (human) : NFATC3 (nuclear factor of activated T cells 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfatc3 (nuclear factor of activated T-cells 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfatc3 (nuclear factor of activated T cells 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NFATC3 (nuclear factor of activated T cells 3)
Canis lupus familiaris (dog) : NFATC3 (nuclear factor of activated T cells 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfatc3 (nuclear factor of activated T cells 3)
Sus scrofa (pig) : NFATC3 (nuclear factor of activated T cells 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm388106,058,818 - 106,130,537 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378108,583,503 - 108,654,437 (+)NCBIGRCm37mm9NCBIm37
MGSCv368108,949,013 - 109,017,574 (+)NCBImm8
Celera8110,287,705 - 110,358,321 (+)NCBICelera
Cytogenetic Map8 D3NCBI
cM Map853.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nfatc3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615176
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.