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Gene: Tgfbr2 (transforming growth factor, beta receptor II) Mus musculus
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Symbol: Tgfbr2
Name: transforming growth factor, beta receptor II
Description: ENCODES a protein that exhibits SMAD binding; transforming growth factor beta binding; transforming growth factor beta-activated receptor activity; INVOLVED IN activation of protein kinase activity; atrioventricular valve morphogenesis; brain development; PARTICIPATES IN altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; glypican signaling pathway; ASSOCIATED WITH abnormal abdominal lymph node morphology; abnormal aorta bulb morphology; abnormal aorta elastic fiber morphology; ASSOCIATED WITH pancreatic ductal carcinoma; Aneurysm (ortholog); aortic aneurysm (ortholog); FOUND IN external side of plasma membrane; caveola (ortholog); cell surface (ortholog); INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110020H15Rik; AU042018; DNIIR; RIIDN; TbetaR-II; TbetaRII; TBR-II; TGF-beta receptor II; TGF-beta receptor type II; TGF-beta receptor type-2; TGF-beta type II receptor; TGFR-2; transforming growth factor-beta receptor type II
Orthologs:
Homo sapiens (human) : TGFBR2 (transforming growth factor beta receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfbr2 (transforming growth factor, beta receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfbr2 (transforming growth factor beta receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFBR2 (transforming growth factor beta receptor 2)
Canis lupus familiaris (dog) : TGFBR2 (transforming growth factor beta receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfbr2 (transforming growth factor beta receptor 2)
Sus scrofa (pig) : TGFBR2 (transforming growth factor beta receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389116,087,695 - 116,175,363 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379115,996,813 - 116,084,481 (-)NCBIGRCm37mm9NCBIm37
MGSCv369115,936,405 - 116,023,987 (-)NCBImm8
Celera9116,548,860 - 116,637,499 (-)NCBICelera
Cytogenetic Map9 F3NCBI
cM Map968.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tgfbr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734333
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.