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Gene: Tgfbr2 (transforming growth factor, beta receptor II) Mus musculus
Symbol: Tgfbr2
Name: transforming growth factor, beta receptor II
Description: ENCODES a protein that exhibits SMAD binding; transforming growth factor beta binding; transforming growth factor beta-activated receptor activity; INVOLVED IN activation of protein kinase activity; atrioventricular valve morphogenesis; brain development; PARTICIPATES IN altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; glypican signaling pathway; ASSOCIATED WITH abnormal abdominal lymph node morphology; abnormal aorta bulb morphology; abnormal aorta elastic fiber morphology; ASSOCIATED WITH pancreatic ductal carcinoma; Aneurysm (ortholog); aortic aneurysm (ortholog); FOUND IN external side of plasma membrane; caveola (ortholog); cell surface (ortholog); INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110020H15Rik; AU042018; DNIIR; RIIDN; TbetaR-II; TbetaRII; TBR-II; TGF-beta receptor II; TGF-beta receptor type II; TGF-beta receptor type-2; TGF-beta type II receptor; TGFR-2; transforming growth factor-beta receptor type II
Homo sapiens (human) : TGFBR2 (transforming growth factor beta receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfbr2 (transforming growth factor, beta receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfbr2 (transforming growth factor beta receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFBR2 (transforming growth factor beta receptor 2)
Canis lupus familiaris (dog) : TGFBR2 (transforming growth factor beta receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfbr2 (transforming growth factor beta receptor 2)
Sus scrofa (pig) : TGFBR2 (transforming growth factor beta receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389116,087,695 - 116,175,363 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379115,996,813 - 116,084,481 (-)NCBIGRCm37mm9NCBIm37
MGSCv369115,936,405 - 116,023,987 (-)NCBImm8
Celera9116,548,860 - 116,637,499 (-)NCBICelera
Cytogenetic Map9 F3NCBI
cM Map968.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tgfbr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734333
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.