Atf4 (activating transcription factor 4) - Rat Genome Database

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Gene: Atf4 (activating transcription factor 4) Mus musculus
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Symbol: Atf4
Name: activating transcription factor 4
RGD ID: 733713
MGI Page MGI
Description: Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; cAMP response element binding protein binding activity; and promoter-specific chromatin binding activity. Contributes to DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including cellular response to leucine starvation; intracellular signal transduction; and regulation of gene expression. Acts upstream of or within several processes, including gluconeogenesis; positive regulation of sodium-dependent phosphate transport; and positive regulation of vascular associated smooth muscle cell apoptotic process. Located in cytoplasm and nucleus. Part of ATF1-ATF4 transcription factor complex and ATF4-CREB1 transcription factor complex. Is expressed in several structures, including central nervous system; embryo ectoderm; eye; genitourinary system; and long bone. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human ATF4 (activating transcription factor 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Atf-; Atf-4; C/AT; C/ATF; c/EBP-related ATF; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; CREB; CREB-2; CREB2; cyclic AMP-dependent transcription factor ATF-4; cyclic AMP-responsive element-binding protein 2; MGC96460; tax-responsive enhancer element-binding protein 67 homolog; TAXREB; TAXREB67; taxREB67 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,139,385 - 80,141,746 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,139,385 - 80,141,742 (+)EnsemblGRCm39 Ensembl
GRCm381580,255,184 - 80,257,545 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1580,255,184 - 80,257,541 (+)EnsemblGRCm38mm10GRCm38
MGSCv371580,085,614 - 80,087,971 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361580,082,756 - 80,084,759 (+)NCBIMGSCv36mm8
Celera1582,372,526 - 82,374,883 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (ISO)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-lipoic acid  (EXP,ISO)
(S)-amphetamine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,4-dithiothreitol  (EXP,ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2-amino-2-deoxy-D-galactopyranose  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-arachidonoylglycerol  (ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-acetyldeoxynivalenol  (EXP)
3-chloropropane-1,2-diol  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-Hydroxybenzophenone  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (EXP,ISO)
4-tert-Octylphenol  (ISO)
5-fluorouracil  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
Alisol B  (ISO)
all-trans-retinal  (ISO)
all-trans-retinoic acid  (EXP)
alpha-D-galactose  (ISO)
aluminium sulfate (anhydrous)  (EXP)
amino acid  (EXP,ISO)
amiodarone  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
atazanavir sulfate  (ISO)
atrazine  (EXP,ISO)
avermectin  (ISO)
azoxystrobin  (ISO)
bathocuproine disulfonic acid  (ISO)
benzalkonium chloride  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bepridil  (ISO)
beta-D-glucosamine  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
bongkrekic acid  (ISO)
boric acid  (ISO)
bortezomib  (EXP,ISO)
brefeldin A  (ISO)
busulfan  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
Butylparaben  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
camptothecin  (ISO)
cannabidiol  (EXP)
cannabigerol  (EXP)
cantharidin  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carboxy-PTIO  (ISO)
cerium  (ISO)
ceruletide  (EXP)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chloroacetaldehyde  (ISO)
chloroacetic acid  (EXP)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chloroquine  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP)
chromium(6+)  (ISO)
chrysene  (EXP)
cibenzoline  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (EXP,ISO)
clodronic acid  (ISO)
clofibrate  (EXP)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corilagin  (EXP)
crocidolite asbestos  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (EXP,ISO)
dantrolene  (EXP,ISO)
dapagliflozin  (ISO)
DDE  (ISO)
deguelin  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP)
Di-n-octyl phthalate  (EXP)
diarsenic trioxide  (EXP,ISO)
Dibromoacetonitrile  (EXP)
dibutyl phthalate  (EXP,ISO)
diclofenac  (EXP,ISO)
diethyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dihydrocapsaicin  (ISO)
Diisodecyl phthalate  (EXP)
diisononyl phthalate  (EXP,ISO)
dimethylarsinic acid  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
epoxomicin  (EXP)
erastin  (ISO)
erlotinib hydrochloride  (ISO)
esketamine  (ISO)
ethanol  (EXP,ISO)
ethylene glycol  (ISO)
etoposide  (EXP)
fangchinoline  (ISO)
fenofibrate  (ISO)
fenpyroximate  (ISO)
ferrostatin-1  (EXP)
flavokawain B  (ISO)
fluoranthene  (EXP)
flutamide  (ISO)
FR900359  (ISO)
fructose  (ISO)
fulvestrant  (EXP)
fumonisin B1  (ISO)
furan  (EXP)
gadolinium trichloride  (ISO)
galactose  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
glafenine  (ISO)
glucose  (EXP,ISO)
glutaraldehyde  (ISO)
glutathione  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
graphene oxide  (ISO)
GSK2656157  (EXP,ISO)
helenalin  (ISO)
hexadecanoic acid  (EXP,ISO)
Honokiol  (ISO)
hydralazine  (EXP)
hydrogen cyanide  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
ibuprofen  (ISO)
ifosfamide  (ISO)
ionomycin  (EXP,ISO)
ivermectin  (EXP,ISO)
ketamine  (EXP)
KN-93  (ISO)
L-1,4-dithiothreitol  (EXP,ISO)
L-cysteine  (ISO)
L-methionine  (ISO)
L-serine  (ISO)
lead diacetate  (EXP,ISO)
lead(II) chloride  (ISO)
leflunomide  (ISO)
Leonurine  (EXP,ISO)
linsidomine  (ISO)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
LY294002  (ISO)
manganese(II) chloride  (ISO)
melatonin  (EXP,ISO)
metformin  (EXP,ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methylmercury chloride  (EXP,ISO)
microcystin-LR  (EXP)
mitomycin C  (EXP,ISO)
MK-2206  (ISO)
montelukast  (EXP)
morphine  (EXP)
N(4)-hydroxycytidine  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-acylsphinganine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-hexadecanoylsphingosine  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-D-aspartic acid  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nelfinavir  (ISO)
niclosamide  (ISO)
nimesulide  (ISO)
Nodularin  (ISO)
Nonidet P-40  (ISO)
NORCANTHARIDIN  (ISO)
ochratoxin A  (ISO)
Octicizer  (EXP)
orlistat  (ISO)
oxidopamine  (ISO)
oxycodone  (ISO)
ozone  (EXP)
p-tert-Amylphenol  (ISO)
Pachymic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parthenolide  (ISO)
Pendulone  (ISO)
perfluorobutyric acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perhexiline  (ISO)
phenanthrene  (ISO)
phenobarbital  (EXP,ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
pitavastatin  (ISO)
pitavastatin(1-)  (ISO)
potassium chromate  (ISO)
potassium dichromate  (EXP,ISO)
procymidone  (EXP)
progesterone  (ISO)
propiconazole  (ISO)
propylparaben  (EXP)
psoralen  (ISO)
pyrazinecarboxamide  (ISO)
pyrimidifen  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rimonabant  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
salubrinal  (EXP,ISO)
SB 203580  (ISO)
SB-239063  (ISO)
SCH 23390  (ISO)
scopoletin  (ISO)
selenium atom  (ISO)
sertraline  (ISO)
sinapic acid  (EXP)
sirolimus  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (ISO)
Soman  (ISO)
sorafenib  (ISO)
SR 144528  (ISO)
streptozocin  (EXP,ISO)
sulfadimethoxine  (ISO)
sulforaphane  (EXP,ISO)
sulindac  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (EXP,ISO)
tauroursodeoxycholic acid  (EXP,ISO)
tebufenpyrad  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP,ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
thymoquinone  (ISO)
Tiron  (EXP,ISO)
titanium dioxide  (EXP)
toosendanin  (EXP,ISO)
tributyl phosphate  (EXP)
Tributyltin oxide  (EXP,ISO)
trichloroethene  (ISO)
triclocarban  (ISO)
triclosan  (ISO)
trimethylamine N-oxide  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (EXP,ISO)
tris(2-butoxyethyl) phosphate  (EXP)
tris(2-chloroethyl) phosphate  (EXP)
troglitazone  (EXP)
trovafloxacin  (EXP)
tunicamycin  (EXP,ISO)
umbelliferone  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
usnic acid  (ISO)
valproic acid  (EXP)
vildagliptin  (ISO)
withaferin A  (ISO)
XAV939  (EXP,ISO)
xylitol  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
bone mineralization  (IMP)
cellular response to amino acid starvation  (IDA,IMP)
cellular response to glucose starvation  (ISO)
cellular response to hypoxia  (ISO)
cellular response to leucine starvation  (IDA,ISO)
cellular response to oxidative stress  (IMP,ISO)
circadian regulation of gene expression  (IMP)
circadian rhythm  (IEP)
embryonic hemopoiesis  (IMP)
endoplasmic reticulum unfolded protein response  (IDA)
gamma-aminobutyric acid signaling pathway  (ISO)
gluconeogenesis  (IDA)
HRI-mediated signaling  (ISO)
integrated stress response signaling  (IMP,ISO)
intracellular calcium ion homeostasis  (IMP)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (IDA,IMP)
L-asparagine metabolic process  (ISO)
lens fiber cell morphogenesis  (IMP)
mRNA transcription by RNA polymerase II  (IDA)
negative regulation of cold-induced thermogenesis  (IMP)
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway  (ISO)
negative regulation of potassium ion transport  (ISO)
negative regulation of transcription by RNA polymerase II  (IMP)
neuron differentiation  (ISO)
PERK-mediated unfolded protein response  (IDA,IMP)
positive regulation of biomineral tissue development  (IMP)
positive regulation of DNA-templated transcription  (IDA,ISO)
positive regulation of gene expression  (IMP,ISO)
positive regulation of neuron apoptotic process  (IMP)
positive regulation of sodium-dependent phosphate transport  (IMP)
positive regulation of transcription by RNA polymerase I  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,IGI,IMP,ISO)
positive regulation of vascular associated smooth muscle cell apoptotic process  (IMP)
positive regulation of vascular endothelial growth factor production  (ISO)
regulation of DNA-templated transcription  (IDA,IMP)
regulation of osteoblast differentiation  (IMP,ISO)
regulation of synaptic plasticity  (IMP)
regulation of transcription by RNA polymerase II  (IBA,IDA)
response to endoplasmic reticulum stress  (IDA,IMP,ISO)
response to manganese-induced endoplasmic reticulum stress  (ISO)
response to nutrient levels  (ISO)
response to toxic substance  (ISO)
rhythmic process  (IEA)
transcription by RNA polymerase II  (IGI)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aorta morphology  (IAGP)
abnormal bone mineralization  (IAGP)
abnormal bone ossification  (IAGP)
abnormal bone structure  (IAGP)
abnormal bone trabecula morphology  (IAGP)
abnormal calcium ion homeostasis  (IAGP)
abnormal ciliary body morphology  (IAGP)
abnormal clavicle morphology  (IAGP)
abnormal frontal bone morphology  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal glycogen homeostasis  (IAGP)
abnormal heart morphology  (IEA)
abnormal iris morphology  (IAGP)
abnormal lens fiber morphology  (IAGP)
abnormal lens morphology  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal osteoblast differentiation  (IAGP)
abnormal pancreas morphology  (IAGP)
abnormal pancreatic acinar cell morphology  (IAGP)
abnormal pancreatic acinar cell zymogen granule morphology  (IAGP)
abnormal pancreatic acinus morphology  (IAGP)
abnormal parietal bone morphology  (IAGP)
abnormal vas deferens morphology  (IAGP)
absent common myeloid progenitor cells  (IAGP)
anemia  (IAGP)
aphakia  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone ossification  (IAGP)
decreased bone trabecula number  (IAGP)
decreased bone volume  (IAGP)
decreased cell proliferation  (IAGP)
decreased circulating glucose level  (IAGP)
decreased fetal size  (IAGP)
decreased hematocrit  (IAGP)
decreased hepatocyte number  (IAGP)
decreased monocyte cell number  (IEA)
decreased susceptibility to induced muscular atrophy  (IAGP)
decreased total fat pad weight  (IAGP)
delayed hair appearance  (IAGP)
enlarged heart  (IEA)
exocrine pancreas hypoplasia  (IAGP)
eyelids fail to open  (IAGP)
female infertility  (IAGP)
impaired gluconeogenesis  (IAGP)
impaired hematopoiesis  (IAGP)
improved glucose tolerance  (IAGP)
increased bone ossification  (IAGP)
increased bone volume  (IAGP)
increased circulating alanine transaminase level  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased circulating insulin level  (IAGP)
increased insulin secretion  (IAGP)
increased insulin sensitivity  (IAGP)
increased lens epithelium apoptosis  (IAGP)
increased pancreatic beta cell mass  (IAGP)
increased pancreatic beta cell proliferation  (IAGP)
increased trabecular bone thickness  (IAGP)
large fontanelles  (IAGP)
male infertility  (IAGP)
microphthalmia  (IAGP)
pale liver  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
reduced male fertility  (IAGP)
ruffled hair  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. STAMP2 increases oxidative stress and is critical for prostate cancer. Jin Y, etal., EMBO Mol Med. 2015 Mar;7(3):315-31. doi: 10.15252/emmm.201404181.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Linares JF, etal., Cell Metab. 2017 Dec 5;26(6):817-829.e6. doi: 10.1016/j.cmet.2017.09.001. Epub 2017 Oct 5.
5. Comparison of Human and Experimental Pulmonary Veno-Occlusive Disease. Manaud G, etal., Am J Respir Cell Mol Biol. 2020 Jul;63(1):118-131. doi: 10.1165/rcmb.2019-0015OC.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. The metabotropic GABAB receptor directly interacts with the activating transcription factor 4. Nehring RB, etal., J Biol Chem 2000 Nov 10;275(45):35185-91.
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. Tan Z, etal., J Neuroinflammation. 2018 Sep 21;15(1):275. doi: 10.1186/s12974-018-1311-5.
15. Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres. Tanaka T, etal., Genes Cells 1998 Dec;3(12):801-10.
16. The impact of the unfolded protein response on human disease. Wang S and Kaufman RJ, J Cell Biol. 2012 Jun 25;197(7):857-67. doi: 10.1083/jcb.201110131.
17. Endoplasmic reticulum stress and neurodegeneration in rats neonatally infected with borna disease virus. Williams BL and Lipkin WI, J Virol. 2006 Sep;80(17):8613-26. doi: 10.1128/JVI.00836-06.
18. miRNA-30a functions as a tumor suppressor by downregulating cyclin E2 expression in castration-resistant prostate cancer. Zhang L, etal., Mol Med Rep. 2016 Sep;14(3):2077-84. doi: 10.3892/mmr.2016.5469. Epub 2016 Jul 6.
Additional References at PubMed
PMID:1371974   PMID:1631061   PMID:1956797   PMID:7892260   PMID:8432535   PMID:8506317   PMID:8889548   PMID:9027489   PMID:9488481   PMID:10349636   PMID:10591541   PMID:10885750  
PMID:10922068   PMID:11025215   PMID:11042159   PMID:11076861   PMID:11106749   PMID:11806972   PMID:11916968   PMID:12477932   PMID:12611881   PMID:12667446   PMID:12749859   PMID:12840028  
PMID:12871976   PMID:12917339   PMID:12925279   PMID:14561648   PMID:14610273   PMID:14630918   PMID:14681479   PMID:14729979   PMID:15013631   PMID:15109498   PMID:15277680   PMID:15377660  
PMID:15576676   PMID:15677469   PMID:15724149   PMID:15775988   PMID:15782199   PMID:15788408   PMID:15866165   PMID:15911876   PMID:16000305   PMID:16141072   PMID:16141073   PMID:16439558  
PMID:16602821   PMID:16751105   PMID:17090218   PMID:17141186   PMID:17141628   PMID:17267404   PMID:17418795   PMID:17726049   PMID:17727724   PMID:17938202   PMID:17967808   PMID:18171674  
PMID:18187540   PMID:18195013   PMID:18228065   PMID:18287559   PMID:18316032   PMID:18346943   PMID:18361414   PMID:18424556   PMID:18437163   PMID:18439838   PMID:18458112   PMID:18480057  
PMID:18522833   PMID:18697751   PMID:18729081   PMID:18768473   PMID:18799693   PMID:18843047   PMID:18955481   PMID:18983980   PMID:19016586   PMID:19017641   PMID:19041748   PMID:19059405  
PMID:19129515   PMID:19139267   PMID:19232401   PMID:19583950   PMID:19605502   PMID:19690063   PMID:19726676   PMID:19726872   PMID:19741146   PMID:19767744   PMID:19815821   PMID:19851510  
PMID:19855386   PMID:19858219   PMID:19906842   PMID:19913500   PMID:20059953   PMID:20066008   PMID:20197309   PMID:20211142   PMID:20392257   PMID:20412781   PMID:20440000   PMID:20473272  
PMID:20592469   PMID:20628199   PMID:20724472   PMID:20732869   PMID:20847738   PMID:21044701   PMID:21113145   PMID:21135100   PMID:21148039   PMID:21159964   PMID:21203563   PMID:21267068  
PMID:21444660   PMID:21606205   PMID:21644928   PMID:21768648   PMID:21788370   PMID:21795745   PMID:21867687   PMID:21873635   PMID:21917591   PMID:22095285   PMID:22102693   PMID:22190639  
PMID:22215680   PMID:22240901   PMID:22298775   PMID:22337954   PMID:22396548   PMID:22496230   PMID:22498744   PMID:22507839   PMID:22556424   PMID:22564414   PMID:22572884   PMID:22628618  
PMID:22643896   PMID:22660795   PMID:22692209   PMID:22745161   PMID:22813743   PMID:22879594   PMID:22925884   PMID:22945629   PMID:22952236   PMID:22955275   PMID:22959274   PMID:22974638  
PMID:22980225   PMID:22988430   PMID:23022383   PMID:23144714   PMID:23176727   PMID:23223004   PMID:23454693   PMID:23494915   PMID:23580573   PMID:23587879   PMID:23611781   PMID:23618921  
PMID:23624402   PMID:23649506   PMID:23663782   PMID:23874395   PMID:23888053   PMID:23941879   PMID:23942974   PMID:23945236   PMID:23990363   PMID:24194600   PMID:24349082   PMID:24362451  
PMID:24373582   PMID:24475193   PMID:24509412   PMID:24673832   PMID:24691093   PMID:24726366   PMID:24895282   PMID:24900988   PMID:24934156   PMID:24952961   PMID:25156122   PMID:25238096  
PMID:25587042   PMID:25657009   PMID:25701401   PMID:25727012   PMID:25857264   PMID:25865882   PMID:25883982   PMID:25915474   PMID:25921292   PMID:26028220   PMID:26030745   PMID:26147683  
PMID:26299268   PMID:26338703   PMID:26383973   PMID:26384355   PMID:26494538   PMID:26519689   PMID:26651292   PMID:26667036   PMID:26816051   PMID:26884599   PMID:26906090   PMID:26960794  
PMID:27040500   PMID:27052593   PMID:27106802   PMID:27144303   PMID:27188441   PMID:27405764   PMID:27452504   PMID:27461142   PMID:27605406   PMID:27613409   PMID:27626668   PMID:27638049  
PMID:27705805   PMID:27812542   PMID:27935748   PMID:27993927   PMID:28030827   PMID:28100675   PMID:28213613   PMID:28237965   PMID:28242759   PMID:28304100   PMID:28331281   PMID:28440222  
PMID:28478109   PMID:28498443   PMID:28539339   PMID:28566324   PMID:28637872   PMID:28688763   PMID:28825160   PMID:29059168   PMID:29180572   PMID:29295856   PMID:29305424   PMID:29317536  
PMID:29378327   PMID:29555819   PMID:29562231   PMID:29666470   PMID:29688375   PMID:29742431   PMID:29803741   PMID:29845243   PMID:29939162   PMID:30385726   PMID:30431065   PMID:30452920  
PMID:30604742   PMID:30635284   PMID:30674717   PMID:30685387   PMID:30703445   PMID:30709400   PMID:30905411   PMID:31216497   PMID:31263264   PMID:31271806   PMID:31433867   PMID:31522764  
PMID:31594848   PMID:31781038   PMID:31787756   PMID:31789450   PMID:31847659   PMID:31953319   PMID:32005751   PMID:32313051   PMID:32389809   PMID:32504036   PMID:32740777   PMID:32754039  
PMID:33055209   PMID:33129879   PMID:33154371   PMID:33198401   PMID:33229553   PMID:33282868   PMID:33443099   PMID:33483347   PMID:33507234   PMID:33512502   PMID:33658516   PMID:33665549  
PMID:33714955   PMID:33901579   PMID:33909046   PMID:33944779   PMID:33948996   PMID:33950334   PMID:34124052   PMID:34157937   PMID:34168130   PMID:34303878   PMID:34358431   PMID:34445595  
PMID:34547510   PMID:34551310   PMID:34680063   PMID:35045271   PMID:35061305   PMID:35129674   PMID:35147267   PMID:35167946   PMID:35237793   PMID:35428325   PMID:35489203   PMID:35574856  
PMID:35724508   PMID:35767995   PMID:35857794   PMID:35977507   PMID:36063172   PMID:36154620   PMID:36227697   PMID:36362372   PMID:36383638   PMID:36421460   PMID:36469355   PMID:36539111  
PMID:36614063   PMID:36624844   PMID:36680386   PMID:36715460   PMID:36841836   PMID:36918894   PMID:36996814   PMID:36996941   PMID:37014538   PMID:37100056   PMID:37273238   PMID:37280306  
PMID:37290760   PMID:37462732   PMID:37481013   PMID:37550596   PMID:37759400   PMID:37967789   PMID:37995805   PMID:37998373   PMID:38113413   PMID:38176727   PMID:38218976   PMID:38229308  
PMID:38238383   PMID:38266827   PMID:38346162   PMID:38355793   PMID:38422489   PMID:38451736   PMID:38588611   PMID:38678560   PMID:38697111   PMID:38849354   PMID:39047038  


Genomics

Comparative Map Data
Atf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,139,385 - 80,141,746 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,139,385 - 80,141,742 (+)EnsemblGRCm39 Ensembl
GRCm381580,255,184 - 80,257,545 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1580,255,184 - 80,257,541 (+)EnsemblGRCm38mm10GRCm38
MGSCv371580,085,614 - 80,087,971 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361580,082,756 - 80,084,759 (+)NCBIMGSCv36mm8
Celera1582,372,526 - 82,374,883 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.85NCBI
ATF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,520,559 - 39,522,686 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,519,695 - 39,522,683 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,916,564 - 39,918,691 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,246,515 - 38,248,637 (+)NCBINCBI36Build 36hg18NCBI36
Build 342238,241,068 - 38,243,191NCBI
Celera2223,718,625 - 23,720,747 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,881,158 - 22,883,280 (+)NCBIHuRef
CHM1_12239,875,308 - 39,877,431 (+)NCBICHM1_1
T2T-CHM13v2.02239,985,692 - 39,993,317 (+)NCBIT2T-CHM13v2.0
Atf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,684,681 - 113,686,739 (+)NCBIGRCr8
mRatBN7.27111,804,135 - 111,806,457 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,804,183 - 111,806,446 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7113,558,983 - 113,561,040 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,782,520 - 115,784,577 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,751,882 - 115,753,939 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07121,480,723 - 121,482,781 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7121,480,723 - 121,482,772 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07121,468,275 - 121,470,587 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47118,537,718 - 118,538,994NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17118,571,947 - 118,573,223NCBI
Cytogenetic Map7q34NCBI
Atf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541325,406,589 - 25,412,218 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541325,406,589 - 25,408,727 (+)NCBIChiLan1.0ChiLan1.0
ATF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22349,368,664 - 49,369,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,058,755 - 52,061,257 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02220,426,743 - 20,428,892 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12238,246,337 - 38,249,333 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2238,248,094 - 38,249,249 (+)Ensemblpanpan1.1panPan2
ATF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11025,528,880 - 25,531,018 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1025,528,874 - 25,530,993 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1025,464,741 - 25,466,879 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01026,280,612 - 26,282,756 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1026,280,619 - 26,282,738 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11025,995,219 - 25,997,329 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01026,314,765 - 26,316,875 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01026,490,223 - 26,492,367 (-)NCBIUU_Cfam_GSD_1.0
Atf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,104,066 - 9,105,487 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,110,634 - 2,115,996 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,114,478 - 2,115,969 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl58,742,967 - 8,745,368 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.158,742,964 - 8,745,752 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,042,584 - 6,044,651 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11922,092,046 - 22,094,184 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1922,091,667 - 22,095,230 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045103,557,595 - 103,561,018 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247528,822,740 - 8,825,032 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247528,822,955 - 8,825,019 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atf4
105 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:69
Interacting mature miRNAs:71
Transcripts:ENSMUST00000109605
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse
15092080Igly7_mIgG glycosylation 7, GP10 (mouse)157779491982674156Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse

Markers in Region
AW050190  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381580,253,850 - 80,253,994UniSTSGRCm38
MGSCv371580,084,280 - 80,084,424UniSTSGRCm37
Celera1582,371,192 - 82,371,336UniSTS
Cytogenetic Map15E1UniSTS
cM Map1543.3UniSTS
Whitehead/MRC_RH15680.84UniSTS
PMC19934P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381580,256,868 - 80,257,347UniSTSGRCm38
MGSCv371580,087,298 - 80,087,777UniSTSGRCm37
Celera1582,374,210 - 82,374,689UniSTS
Cytogenetic Map15E1UniSTS
cM Map1543.3UniSTS
Atf4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381580,257,174 - 80,257,422UniSTSGRCm38
MGSCv371580,085,933 - 80,086,108UniSTSGRCm37
MGSCv371580,085,979 - 80,087,196UniSTSGRCm37
Celera1582,374,516 - 82,374,764UniSTS
Cytogenetic Map15E1UniSTS
cM Map1543.3UniSTS
cM Map1543.3UniSTS
Atf4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381580,255,549 - 80,256,766UniSTSGRCm38
MGSCv371580,085,979 - 80,087,196UniSTSGRCm37
Celera1582,372,891 - 82,374,108UniSTS
Cytogenetic Map15E1UniSTS
Atf4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381580,255,503 - 80,255,678UniSTSGRCm38
MGSCv371580,085,933 - 80,086,108UniSTSGRCm37
Celera1582,372,845 - 82,373,020UniSTS
Cytogenetic Map15E1UniSTS
cM Map1543.3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001287180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA003141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE992821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L13791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M94087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X61507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000109605   ⟹   ENSMUSP00000105234
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1580,139,385 - 80,141,742 (+)Ensembl
GRCm38.p6 Ensembl1580,255,184 - 80,257,541 (+)Ensembl
Ensembl Acc Id: ENSMUST00000229828   ⟹   ENSMUSP00000155806
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1580,139,386 - 80,140,960 (+)Ensembl
GRCm38.p6 Ensembl1580,255,185 - 80,256,759 (+)Ensembl
Ensembl Acc Id: ENSMUST00000230434
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1580,139,724 - 80,141,742 (+)Ensembl
GRCm38.p6 Ensembl1580,255,523 - 80,257,541 (+)Ensembl
RefSeq Acc Id: NM_001287180   ⟹   NP_001274109
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391580,139,385 - 80,141,746 (+)NCBI
GRCm381580,255,184 - 80,257,545 (+)NCBI
Celera1582,372,526 - 82,374,887 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009716   ⟹   NP_033846
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391580,139,385 - 80,141,746 (+)NCBI
GRCm381580,255,184 - 80,257,545 (+)NCBI
MGSCv371580,085,614 - 80,087,971 (+)RGD
Celera1582,372,526 - 82,374,887 (+)NCBI
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033846   ⟸   NM_009716
- UniProtKB: Q5U4B2 (UniProtKB/Swiss-Prot),   Q61906 (UniProtKB/Swiss-Prot),   Q06507 (UniProtKB/Swiss-Prot),   Q3U2J1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001274109   ⟸   NM_001287180
- UniProtKB: Q5U4B2 (UniProtKB/Swiss-Prot),   Q61906 (UniProtKB/Swiss-Prot),   Q06507 (UniProtKB/Swiss-Prot),   Q3U2J1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000105234   ⟸   ENSMUST00000109605
Ensembl Acc Id: ENSMUSP00000155806   ⟸   ENSMUST00000229828
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q06507-F1-model_v2 AlphaFold Q06507 1-349 view protein structure

Promoters
RGD ID:6825792
Promoter ID:MM_KWN:19110
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_009716
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361580,085,311 - 80,086,012 (+)MPROMDB
RGD ID:6825790
Promoter ID:MM_KWN:19111
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_