Tnfsf11 (tumor necrosis factor (ligand) superfamily, member 11) - Rat Genome Database

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Gene: Tnfsf11 (tumor necrosis factor (ligand) superfamily, member 11) Mus musculus
Analyze
Symbol: Tnfsf11
Name: tumor necrosis factor (ligand) superfamily, member 11
RGD ID: 1551655
MGI Page MGI
Description: Enables identical protein binding activity; receptor ligand activity; and tumor necrosis factor receptor superfamily binding activity. Involved in several processes, including intracellular signaling cassette; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of secretion by cell. Acts upstream of or within several processes, including cellular response to cytokine stimulus; mammary gland development; and positive regulation of intracellular signal transduction. Predicted to be located in cytoplasm; extracellular space; and plasma membrane. Is expressed in bone; genitourinary system; hemolymphoid system; incisor; and rib. Used to study autosomal recessive osteopetrosis 2 and osteoporosis. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 2 and osteoporosis. Orthologous to human TNFSF11 (TNF superfamily member 11).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ly10; Ly109l; O; OD; ODF; OPG; OPG ligand; OPGL; osteoclast differentiation factor; osteoprotegerin ligand; R; RANKL; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; TNF-related activation-induced cytokine; Tra; Trance; tumor necrosis factor ligand superfamily member 11; tumor necrosis factor-related activation-induced cytokine
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391478,514,886 - 78,545,483 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1478,514,885 - 78,545,483 (-)EnsemblGRCm39 Ensembl
GRCm381478,277,446 - 78,308,043 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1478,277,445 - 78,308,043 (-)EnsemblGRCm38mm10GRCm38
MGSCv371478,677,253 - 78,707,850 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361477,009,005 - 77,042,170 (-)NCBIMGSCv36mm8
Celera1475,790,488 - 75,821,164 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1441.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-anisomycin  (EXP)
(-)-matairesinol  (EXP)
(20S)-ginsenoside Rg3  (ISO)
(S)-nicotine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-aminopurine  (EXP)
2-tert-butylhydroquinone  (EXP)
23-epi-26-deoxyactein  (EXP)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP)
4',5,7-trihydroxy-3'-methoxyflavone  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide  (EXP)
4-nitroquinoline N-oxide  (EXP)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
acrolein  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
alendronic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-naphthoflavone  (EXP)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
amsacrine  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antimycin A  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atazanavir sulfate  (ISO)
ATP  (EXP)
belinostat  (ISO)
benzamide  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
benzyl isothiocyanate  (EXP)
Bergenin  (EXP)
beta-D-glucosamine  (ISO)
betulinic acid  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calciol  (EXP,ISO)
calcitriol  (EXP,ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
cannabidiol  (EXP)
carbocyclic thromboxane A2  (ISO)
carbon nanotube  (EXP)
chenodeoxycholic acid  (ISO)
chlormequat chloride  (ISO)
chlorpromazine  (EXP)
chondroitin sulfate  (ISO)
chromium(3+) trichloride  (EXP)
cisapride  (EXP)
cobalt dichloride  (EXP)
coenzyme Q10  (EXP)
corilagin  (EXP)
corticosterone  (ISO)
crocin-1  (EXP)
curcumin  (EXP,ISO)
cycloheximide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
Cyclosporin H  (EXP)
daidzein  (ISO)
decabromodiphenyl ether  (ISO)
dehydrocostus lactone  (EXP)
deoxycholic acid  (ISO)
desferrioxamine B  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dihydro-beta-erythroidine  (ISO)
dimethyl fumarate  (EXP)
dimethylarsinic acid  (EXP,ISO)
dioscin  (EXP)
diosgenin  (EXP)
dorsomorphin  (EXP,ISO)
ellagic acid  (EXP)
entinostat  (ISO)
ethanol  (EXP,ISO)
etoposide  (EXP)
fluoxetine  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (EXP,ISO)
furosemide  (ISO)
gadolinium trichloride  (ISO)
genistein  (EXP)
gentamycin  (ISO)
ginsenoside Rb1  (EXP)
glycerol 2-phosphate  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
icariin  (EXP)
icariside II  (ISO)
Icaritin  (ISO)
indometacin  (ISO)
iron dextran  (ISO)
kaempferol  (EXP)
KN-93  (EXP)
KT 5720  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (EXP,ISO)
lithocholic acid  (ISO)
loganin  (EXP)
lovastatin  (EXP)
LY294002  (EXP)
mangiferin  (EXP)
menadione  (ISO)
menaquinone  (ISO)
menaquinone-4  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methylarsonic acid  (EXP)
methylglyoxal  (EXP)
methylmercury chloride  (ISO)
mifepristone  (ISO)
miquelianin  (EXP)
modafinil  (ISO)
morin  (ISO)
Morroniside  (EXP)
myricitrin  (EXP,ISO)
N-acetyl-L-cysteine  (EXP)
N-ethyl-5'-carboxamidoadenosine  (ISO)
N-nitrosodiethylamine  (ISO)
naringin  (EXP)
nefazodone  (ISO)
nickel atom  (ISO)
niclosamide  (EXP,ISO)
nicotinamide  (EXP)
nicotine  (ISO)
nimesulide  (EXP)
o-anisidine  (ISO)
oxybenzone  (EXP)
ozagrel  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paricalcitol  (ISO)
pentobarbital  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (ISO)
platycodin D  (EXP,ISO)
poly(ethylene)  (ISO)
prazosin  (EXP)
progesterone  (EXP,ISO)
promethazine  (EXP)
puerarin  (ISO)
quercetin  (EXP)
raloxifene  (EXP,ISO)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
riboflavin  (EXP)
Ro 41-5253  (EXP)
rotenone  (ISO)
rubiadin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 203580  (EXP)
SB 431542  (EXP,ISO)
sclareol  (EXP)
silicon dioxide  (EXP,ISO)
sirolimus  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
sulfasalazine  (ISO)
Sunset Yellow FCF  (ISO)
tacrolimus hydrate  (EXP)
tartrazine  (ISO)
telmisartan  (ISO)
testosterone  (ISO)
thalidomide  (ISO)
Theaflavin 3,3'-digallate  (EXP)
thiram  (ISO)
thymol  (EXP)
thymol sulfate(1-)  (EXP)
titanium atom  (ISO)
titanium dioxide  (EXP)
tofacitinib  (EXP,ISO)
tributylstannane  (EXP)
Tributyltin oxide  (EXP)
trichostatin A  (ISO)
trifluoperazine  (EXP)
triphenylstannane  (EXP)
troglitazone  (EXP)
tungsten  (EXP)
uranium atom  (EXP,ISO)
valproic acid  (EXP,ISO)
vitamin D  (EXP,ISO)
vorinostat  (ISO)
xanthohumol  (EXP)
zinc dichloride  (ISO)
zinc sulfate  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (IMP)
bone development  (IMP)
bone resorption  (IDA)
calcium ion homeostasis  (IGI)
calcium-mediated signaling  (IDA)
cell differentiation  (IEA)
cellular response to leukemia inhibitory factor  (IEP)
cytokine-mediated signaling pathway  (ISO)
ERK1 and ERK2 cascade  (IDA)
immune response  (IEA)
JNK cascade  (IGI)
lymph node development  (TAS)
mammary gland alveolus development  (IMP)
mammary gland epithelial cell proliferation  (IMP)
monocyte chemotaxis  (ISO)
negative regulation of transcription by RNA polymerase II  (IMP)
ossification  (IMP)
osteoclast development  (IDA)
osteoclast differentiation  (IDA,IGI,IMP,ISO)
osteoclast proliferation  (IDA)
paracrine signaling  (IDA)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IMP)
positive regulation of bone resorption  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (IDA)
positive regulation of corticotropin-releasing hormone secretion  (IDA)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fever generation by positive regulation of prostaglandin secretion  (IDA)
positive regulation of gene expression  (IDA)
positive regulation of homotypic cell-cell adhesion  (ISO)
positive regulation of intracellular signal transduction  (ISO)
positive regulation of JNK cascade  (IGI)
positive regulation of osteoclast development  (IDA)
positive regulation of osteoclast differentiation  (IDA,IGI,IMP,ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IMP)
positive regulation of phosphorylation  (IDA)
positive regulation of T cell activation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
regulation of osteoclast differentiation  (IDA)
response to ethanol  (ISO)
response to immobilization stress  (ISO)
tooth eruption  (IMP)
tumor necrosis factor-mediated signaling pathway  (IDA,IGI,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal areal bone mineral density  (IAGP)
abnormal bone marrow morphology  (IAGP)
abnormal bone ossification  (IAGP)
abnormal bone structure  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal cervical lymph node morphology  (IAGP)
abnormal chondrocyte differentiation  (IAGP)
abnormal chondrocyte morphology  (IAGP)
abnormal cranial suture morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal femur morphology  (IAGP)
abnormal hyoid bone body morphology  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal long bone epiphyseal plate morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal long bone internal diameter  (IAGP)
abnormal long bone metaphysis morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal mammary gland growth during pregnancy  (IAGP)
abnormal maternal nurturing  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal osteoblast physiology  (IAGP)
abnormal osteoclast cell number  (IAGP)
abnormal pelvic girdle bone morphology  (IAGP)
abnormal pro-B cell differentiation  (IAGP)
abnormal spleen B cell follicle morphology  (IAGP)
abnormal spleen marginal zone morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal tail length  (IAGP)
abnormal thymus cell ratio  (IAGP)
abnormal thymus epithelium morphology  (IAGP)
abnormal tooth eruption  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal zygomatic bone morphology  (IAGP)
absent cervical lymph nodes  (IAGP)
absent lymph nodes  (IAGP)
absent mesenteric lymph nodes  (IAGP)
absent peripheral lymph nodes  (IAGP)
arrested T cell differentiation  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone resorption  (IAGP)
decreased bone trabecula number  (IAGP)
decreased circulating calcium level  (IAGP)
decreased compact bone thickness  (IAGP)
decreased cranium height  (IAGP)
decreased immature B cell number  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased interleukin-2 secretion  (IAGP)
decreased interleukin-4 secretion  (IAGP)
decreased interleukin-5 secretion  (IAGP)
decreased interleukin-6 secretion  (IAGP)
decreased internal diameter of femur  (IAGP)
decreased Langerhans cell number  (IAGP)
decreased lean body mass  (IAGP)
decreased length of long bones  (IAGP)
decreased mature B cell number  (IAGP)
decreased osteoclast cell number  (IAGP)
decreased osteosarcoma incidence  (IAGP)
decreased Peyer's patch number  (IAGP)
decreased spleen white pulp amount  (IAGP)
decreased thymus weight  (IAGP)
dystrophic muscle  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
failure of tooth eruption  (IAGP)
increased areal bone mineral density  (IAGP)
increased bone mass  (IAGP)
increased bone mineral content  (IAGP)
increased bone mineral density  (IAGP)
increased bone mineral density of femur  (IAGP)
increased bone mineral density of vertebrae  (IAGP)
increased bone mineralization  (IAGP)
increased bone trabecula number  (IAGP)
increased bone trabecular spacing  (IAGP)
increased bone volume  (IAGP)
increased diameter of long bones  (IAGP)
increased diameter of tibia  (IAGP)
increased long bone epiphyseal plate size  (IAGP)
increased osteosarcoma incidence  (IAGP)
increased spleen red pulp amount  (IAGP)
increased spleen weight  (IAGP)
increased trabecular bone thickness  (IAGP)
increased trabecular bone volume  (IAGP)
increased width of hypertrophic chondrocyte zone  (IAGP)
kyphosis  (IAGP)
lactation failure  (IAGP)
macrocytic anemia  (IAGP)
mandible hypoplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
optic canal stenosis  (IAGP)
osteopetrosis  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
reduced fertility  (IAGP)
round face  (IAGP)
short tibia  (IAGP)
short vertebral column  (IAGP)
small cranium  (IAGP)
small Peyer's patches  (IAGP)
small thymus medulla  (IAGP)
supernumerary teeth  (IAGP)
thin neurocranium  (IAGP)
thymus hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease. Brito VGB, etal., Front Pharmacol. 2020 Nov 11;11:579926. doi: 10.3389/fphar.2020.579926. eCollection 2020.
2. Imbalance of RANK, RANKL and OPG expression during tibial fracture repair in diabetic rats. de Amorim FP, etal., J Mol Histol. 2008 Aug;39(4):401-8. Epub 2008 Jul 1.
3. Anti-TNF-alpha therapy enhances the effects of enzyme replacement therapy in rats with mucopolysaccharidosis type VI. Eliyahu E, etal., PLoS One. 2011;6(8):e22447. doi: 10.1371/journal.pone.0022447. Epub 2011 Aug 22.
4. Serum levels of the osteoprotegerin, receptor activator of nuclear factor kappa-B ligand, metalloproteinase-1 (MMP-1) and tissue inhibitors of MMP-1 levels are increased in men 6 months after acute myocardial infarction. Halapas A, etal., Clin Chem Lab Med. 2008;46(4):510-6.
5. Osteoprotegerin/RANK/RANKL axis in cardiac remodeling due to immuno-inflammatory myocardial disease. Liu W, etal., Exp Mol Pathol. 2008 Jun;84(3):213-7. Epub 2008 Mar 7.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction. Xiong DH, etal., J Bone Miner Res. 2006 Nov;21(11):1678-95.
Additional References at PubMed
PMID:9312132   PMID:9367155   PMID:9396779   PMID:9520411   PMID:9568710   PMID:9730902   PMID:9774460   PMID:9837769   PMID:9950424   PMID:10080918   PMID:10196481   PMID:10224132  
PMID:10349636   PMID:10574572   PMID:10580503   PMID:10687308   PMID:10952716   PMID:10984520   PMID:11042159   PMID:11051546   PMID:11076861   PMID:11085748   PMID:11117749   PMID:11217851  
PMID:11239407   PMID:11250921   PMID:11581298   PMID:11696430   PMID:11697804   PMID:11726661   PMID:11733492   PMID:11785948   PMID:11804028   PMID:11827970   PMID:11859102   PMID:11918218  
PMID:11920576   PMID:11923298   PMID:11930176   PMID:11961557   PMID:12054573   PMID:12162499   PMID:12167715   PMID:12193704   PMID:12211438   PMID:12244151   PMID:12387822   PMID:12434161  
PMID:12477932   PMID:12490655   PMID:12540577   PMID:12548564   PMID:12568404   PMID:12568405   PMID:12594294   PMID:12619928   PMID:12663664   PMID:12692138   PMID:12697767   PMID:12700082  
PMID:12727216   PMID:12824189   PMID:12854843   PMID:12923331   PMID:12952207   PMID:12952963   PMID:12975380   PMID:14499638   PMID:14500523   PMID:14500574   PMID:14500659   PMID:14506249  
PMID:14607948   PMID:14634009   PMID:14645259   PMID:14662855   PMID:14673146   PMID:14734743   PMID:14969390   PMID:14969393   PMID:14977979   PMID:14981127   PMID:15033472   PMID:15085135  
PMID:15108059   PMID:15137062   PMID:15145935   PMID:15213096   PMID:15314684   PMID:15315973   PMID:15340228   PMID:15355564   PMID:15389882   PMID:15389885   PMID:15474477   PMID:15485831  
PMID:15530848   PMID:15563837   PMID:15564564   PMID:15585657   PMID:15619676   PMID:15642143   PMID:15647836   PMID:15657444   PMID:15668736   PMID:15670755   PMID:15670856   PMID:15678102  
PMID:15694411   PMID:15724149   PMID:15731115   PMID:15750601   PMID:15752732   PMID:15757905   PMID:15814301   PMID:15817678   PMID:15845617   PMID:15855336   PMID:15866165   PMID:15894268  
PMID:15919368   PMID:16052479   PMID:16059638   PMID:16109714   PMID:16141072   PMID:16141073   PMID:16147974   PMID:16166629   PMID:16200600   PMID:16234249   PMID:16234979   PMID:16251181  
PMID:16306046   PMID:16322470   PMID:16326388   PMID:16365894   PMID:16391513   PMID:16428453   PMID:16479591   PMID:16514640   PMID:16522681   PMID:16537572   PMID:16549048   PMID:16572175  
PMID:16598781   PMID:16614077   PMID:16627581   PMID:16680194   PMID:16680826   PMID:16750945   PMID:16815304   PMID:16821125   PMID:16828054   PMID:16831954   PMID:16877352   PMID:16897342  
PMID:16914731   PMID:16914732   PMID:16927271   PMID:16951341   PMID:17002555   PMID:17008384   PMID:17018528   PMID:17038532   PMID:17042716   PMID:17052691   PMID:17053039   PMID:17053831  
PMID:17128269   PMID:17141628   PMID:17143276   PMID:17158225   PMID:17182555   PMID:17222389   PMID:17243865   PMID:17328065   PMID:17363454   PMID:17371940   PMID:17403683   PMID:17442941  
PMID:17442949   PMID:17467668   PMID:17477372   PMID:17485464   PMID:17488193   PMID:17495007   PMID:17498702   PMID:17549395   PMID:17549607   PMID:17572386   PMID:17683568   PMID:17694327  
PMID:17729310   PMID:17878071   PMID:17881498   PMID:17928529   PMID:17932217   PMID:17957725   PMID:17963723   PMID:17967138   PMID:17971207   PMID:18008334   PMID:18021007   PMID:18063694  
PMID:18064531   PMID:18172035   PMID:18269914   PMID:18281276   PMID:18284919   PMID:18287559   PMID:18297083   PMID:18305399   PMID:18327666   PMID:18358842   PMID:18440890   PMID:18458345  
PMID:18464930   PMID:18477451   PMID:18543257   PMID:18567579   PMID:18586671   PMID:18606662   PMID:18606706   PMID:18617513   PMID:18632634   PMID:18668542   PMID:18668550   PMID:18705798  
PMID:18728019   PMID:18762192   PMID:18788552   PMID:18789397   PMID:18799149   PMID:18799150   PMID:18814144   PMID:18927151   PMID:18929692   PMID:18931513   PMID:18952894   PMID:19008464  
PMID:19112497   PMID:19113915   PMID:19120972   PMID:19167994   PMID:19197242   PMID:19252502   PMID:19258321   PMID:19262012   PMID:19285079   PMID:19298785   PMID:19299513   PMID:19336404  
PMID:19365810   PMID:19380791   PMID:19393224   PMID:19405951   PMID:19409483   PMID:19414759   PMID:19419298   PMID:19419302   PMID:19419309   PMID:19419310   PMID:19453995   PMID:19557172  
PMID:19563866   PMID:19576893   PMID:19585227   PMID:19590968   PMID:19633200   PMID:19661463   PMID:19715671   PMID:19723499   PMID:19725047   PMID:19728893   PMID:19737917   PMID:19770515  
PMID:19782692   PMID:19801646   PMID:19819969   PMID:19819976   PMID:19822644   PMID:19828638   PMID:19880655   PMID:19940926   PMID:20001844   PMID:20059964   PMID:20109072   PMID:20118276  
PMID:20133621   PMID:20142103   PMID:20179096   PMID:20200944   PMID:20200993   PMID:20237296   PMID:20357249   PMID:20369527   PMID:20391022   PMID:20439489   PMID:20440000   PMID:20558734  
PMID:20560139   PMID:20605949   PMID:20633538   PMID:20635397   PMID:20663885   PMID:20671239   PMID:20691668   PMID:20696287   PMID:20729550   PMID:20818496   PMID:20828639   PMID:20881963  
PMID:20890037   PMID:20939018   PMID:20939024   PMID:20963600   PMID:21048959   PMID:21059944   PMID:21063739   PMID:21068407   PMID:21078845   PMID:21148188   PMID:21267068   PMID:21290130  
PMID:21308779   PMID:21326202   PMID:21332025   PMID:21351141   PMID:21356377   PMID:21402940   PMID:21441458   PMID:21447555   PMID:21454810   PMID:21464945   PMID:21465526   PMID:21466864  
PMID:21478097   PMID:21487009   PMID:21494622   PMID:21527253   PMID:21561598   PMID:21611968   PMID:21651855   PMID:21656335   PMID:21677750   PMID:21679949   PMID:21680703   PMID:21715325  
PMID:21734075   PMID:21750093   PMID:21751242   PMID:21784849   PMID:21810381   PMID:21835177   PMID:21841309   PMID:21854748   PMID:21862583   PMID:21873635   PMID:21898536   PMID:21909103  
PMID:21909105   PMID:21925926   PMID:21939752   PMID:21947283   PMID:21981321   PMID:21982707   PMID:21991382   PMID:22006978   PMID:22068587   PMID:22073305   PMID:22075210   PMID:22088466  
PMID:22105856   PMID:22125315   PMID:22190112   PMID:22207718   PMID:22210913   PMID:22298642   PMID:22307584   PMID:22354913   PMID:22382685   PMID:22387224   PMID:22437732   PMID:22449704  
PMID:22451653   PMID:22454522   PMID:22457635   PMID:22564414   PMID:22615494   PMID:22646472   PMID:22670054   PMID:22768243   PMID:22776139   PMID:22778137   PMID:22782898   PMID:22807088  
PMID:22830570   PMID:22836362   PMID:22848465   PMID:22899855   PMID:22952578   PMID:23039992   PMID:23052229   PMID:23071670   PMID:23085426   PMID:23099324   PMID:23109727   PMID:23142594  
PMID:23152561   PMID:23204328   PMID:23246654   PMID:23268391   PMID:23295770   PMID:23303310   PMID:23303667   PMID:23319583   PMID:23321670   PMID:23322385   PMID:23323745   PMID:23357366  
PMID:23395171   PMID:23419777   PMID:23462470   PMID:23478294   PMID:23499553   PMID:23509071   PMID:23529793   PMID:23536580   PMID:23538677   PMID:23567158   PMID:23607938   PMID:23619911  
PMID:23665018   PMID:23895994   PMID:23908115   PMID:23954298   PMID:23980096   PMID:23990468   PMID:23996528   PMID:24014480   PMID:24014651   PMID:24039232   PMID:24039733   PMID:24040204  
PMID:24065669   PMID:24127173   PMID:24129162   PMID:24161214   PMID:24190884   PMID:24236172   PMID:24278237   PMID:24324158   PMID:24465914   PMID:24642764   PMID:24664887   PMID:24733562  
PMID:24752296   PMID:24753250   PMID:24757287   PMID:24813642   PMID:24847069   PMID:24862038   PMID:24877630   PMID:24929185   PMID:24933342   PMID:24948010   PMID:24950406   PMID:25017214  
PMID:25047844   PMID:25138550   PMID:25163928   PMID:25187507   PMID:25205203   PMID:25220258   PMID:25301844   PMID:25401279   PMID:25431114   PMID:25448849   PMID:25460576   PMID:25464126  
PMID:25503582   PMID:25518928   PMID:25554597   PMID:25656537   PMID:25668130   PMID:25677506   PMID:25701138   PMID:25706873   PMID:25708645   PMID:25721666   PMID:25733371   PMID:25736226  
PMID:25795135   PMID:25825446   PMID:25863233   PMID:25864714   PMID:25955862   PMID:26038599   PMID:26044505   PMID:26061636   PMID:26075897   PMID:26085099   PMID:26094741   PMID:26094846  
PMID:26110849   PMID:26112372   PMID:26120583   PMID:26149648   PMID:26220341   PMID:26234751   PMID:26265539   PMID:26324422   PMID:26329402   PMID:26332516   PMID:26366858   PMID:26373710  
PMID:26378628   PMID:26393791   PMID:26429739   PMID:26546523   PMID:26553655   PMID:26553756   PMID:26563612   PMID:26571489   PMID:26642432   PMID:26646205   PMID:26648171   PMID:26659571  
PMID:26670608   PMID:26680207   PMID:26684711   PMID:26687997   PMID:26695351   PMID:26713363   PMID:26744072   PMID:26766771   PMID:26783750   PMID:26792726   PMID:26825553   PMID:26825871  
PMID:26852281   PMID:26894505   PMID:26923114   PMID:26999703   PMID:27010197   PMID:27035226   PMID:27052174   PMID:27142480   PMID:27179783   PMID:27188231   PMID:27241552   PMID:27311019  
PMID:27336669   PMID:27349866   PMID:27401343   PMID:27402532   PMID:27413168   PMID:27441652   PMID:27460899   PMID:27485735   PMID:27596806   PMID:27606829   PMID:27608420   PMID:27621061  
PMID:27697839   PMID:27706599   PMID:27733688   PMID:27778412   PMID:27804995   PMID:27836987   PMID:27856256   PMID:27913299   PMID:28077433   PMID:28100034   PMID:28161637   PMID:28213978  
PMID:28278513   PMID:28287403   PMID:28349965   PMID:28419519   PMID:28436956   PMID:28438834   PMID:28455312   PMID:28464271   PMID:28589412   PMID:28624040   PMID:28627025   PMID:28634284  
PMID:28637991   PMID:28661042   PMID:28681916   PMID:28709835   PMID:28739641   PMID:28744019   PMID:28760341   PMID:28771720   PMID:28821826   PMID:28882590   PMID:28914985   PMID:29047264  
PMID:29115382   PMID:29118048   PMID:29183803   PMID:29202462   PMID:29269297   PMID:29292230   PMID:29345352   PMID:29378912   PMID:29382610   PMID:29401593   PMID:29453398   PMID:29512766  
PMID:29572179   PMID:29577879   PMID:29685509   PMID:29724913   PMID:29858011   PMID:29904917   PMID:29932225   PMID:30001863   PMID:30013437   PMID:30031905   PMID:30046091   PMID:30154485  
PMID:30185903   PMID:30201326   PMID:30292447   PMID:30317692   PMID:30338925   PMID:30343452   PMID:30399207   PMID:30418981   PMID:30422320   PMID:30471112   PMID:30506812   PMID:30511172  
PMID:30594398   PMID:30626205   PMID:30684382   PMID:30686531   PMID:30689868   PMID:30711250   PMID:30760811   PMID:30815894   PMID:30914204   PMID:30936475   PMID:31081236   PMID:31127627  
PMID:31167789   PMID:31191537   PMID:31201093   PMID:31202927   PMID:31208720   PMID:31226438   PMID:31244859   PMID:31356686   PMID:31432164   PMID:31480885   PMID:31543513   PMID:31545469  
PMID:31619522   PMID:31822662   PMID:31889368   PMID:31964464   PMID:32053272   PMID:32102755   PMID:32169280   PMID:32186512   PMID:32197293   PMID:32202502   PMID:32307402   PMID:32315212  
PMID:32477357   PMID:32583887   PMID:32596356   PMID:32600615   PMID:32604472   PMID:32636266   PMID:32652826   PMID:32698011   PMID:32718089   PMID:32790170   PMID:32792620   PMID:32854285  
PMID:32870816   PMID:32901120   PMID:32938907   PMID:33114380   PMID:33141273   PMID:33142674   PMID:33159483   PMID:33253203   PMID:33255852   PMID:33385614   PMID:33416111   PMID:33452455  
PMID:33477539   PMID:33633362   PMID:33636130   PMID:33689672   PMID:33707780   PMID:33720039   PMID:33754447   PMID:33810014   PMID:33893301   PMID:33970941   PMID:34052656   PMID:34172578  
PMID:34212684   PMID:34248133   PMID:34443530   PMID:34498703   PMID:34585393   PMID:34594237   PMID:34847079   PMID:34847428   PMID:34933640   PMID:34946658   PMID:35031565   PMID:35048384  
PMID:35216486   PMID:35266010   PMID:35689447   PMID:35751983   PMID:35851381   PMID:36099756   PMID:36194667   PMID:36210025   PMID:36580846   PMID:36726200   PMID:36835016   PMID:37296659  
PMID:37298085   PMID:37338990   PMID:37551879   PMID:37568820   PMID:37575184   PMID:37704707   PMID:37792417   PMID:37910614   PMID:38048727   PMID:38431690   PMID:38614129   PMID:38749090  
PMID:38776732  


Genomics

Comparative Map Data
Tnfsf11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391478,514,886 - 78,545,483 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1478,514,885 - 78,545,483 (-)EnsemblGRCm39 Ensembl
GRCm381478,277,446 - 78,308,043 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1478,277,445 - 78,308,043 (-)EnsemblGRCm38mm10GRCm38
MGSCv371478,677,253 - 78,707,850 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361477,009,005 - 77,042,170 (-)NCBIMGSCv36mm8
Celera1475,790,488 - 75,821,164 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1441.26NCBI
TNFSF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381342,562,736 - 42,608,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1342,562,736 - 42,608,013 (+)EnsemblGRCh38hg38GRCh38
GRCh371343,136,872 - 43,182,149 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361342,043,795 - 42,080,148 (+)NCBINCBI36Build 36hg18NCBI36
Build 341342,043,794 - 42,080,148NCBI
Celera1324,194,611 - 24,239,896 (+)NCBICelera
Cytogenetic Map13q14.11NCBI
HuRef1323,940,423 - 23,985,716 (+)NCBIHuRef
CHM1_11343,104,338 - 43,149,624 (+)NCBICHM1_1
T2T-CHM13v2.01341,782,656 - 41,827,951 (+)NCBIT2T-CHM13v2.0
Tnfsf11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81560,083,008 - 60,114,479 (-)NCBIGRCr8
mRatBN7.21553,673,850 - 53,705,325 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1553,673,877 - 53,705,445 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1557,808,333 - 57,838,504 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01558,926,702 - 58,956,875 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01555,751,584 - 55,781,751 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01560,482,527 - 60,512,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1560,482,527 - 60,512,704 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01565,726,538 - 65,757,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01564,155,680 - 64,186,116 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41559,397,837 - 59,428,014 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11559,413,616 - 59,443,794 (-)NCBI
Celera1553,271,197 - 53,300,935 (-)NCBICelera
Cytogenetic Map15q11NCBI
Tnfsf11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955518430,642 - 462,705 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955518431,401 - 462,063 (+)NCBIChiLan1.0ChiLan1.0
TNFSF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21442,065,957 - 42,099,896 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11333,169,616 - 33,203,518 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01323,750,835 - 23,784,740 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TNFSF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1228,226,931 - 8,257,926 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl228,227,555 - 8,258,645 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha228,218,782 - 8,249,783 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0228,445,691 - 8,476,717 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl228,446,327 - 8,477,037 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1228,136,967 - 8,174,247 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0228,193,944 - 8,224,951 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0228,205,225 - 8,236,245 (-)NCBIUU_Cfam_GSD_1.0
Tnfsf11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945152,785,812 - 152,819,281 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367471,255,803 - 1,288,252 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367471,255,803 - 1,288,252 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFSF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1124,468,110 - 24,505,477 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11124,468,011 - 24,505,421 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21125,117,332 - 25,154,855 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TNFSF11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1320,717,884 - 20,761,520 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl320,727,592 - 20,760,408 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605723,446,636 - 23,492,542 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnfsf11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474812,527,478 - 12,555,405 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474812,527,221 - 12,555,551 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tnfsf11
880 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1043
Count of miRNA genes:458
Interacting mature miRNAs:564
Transcripts:ENSMUST00000022592
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
1301844Pgia29_mproteoglycan induced arthritis 29 (mouse)Not determined1474352296108352384Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145608238190082509Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145654674590546941Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1458179640101859473Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146239746096397680Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
11039527Ccc2_mcolitis susceptibility in the Collaborative Cross 2 (mouse)145991861294138217Mouse
1558823Tbbmd6_mtotal body bone mineral density 6 (mouse)Not determined1477073696111073787Mouse
10054475Ossc3_mosteosarcoma susceptibility 3 (mouse)Not determined1470863768104863926Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
1300551Lprm3_mlymphoproliferation modifier 3 (mouse)Not determined1471221224105221344Mouse
1558819Ossc2_mosteosarcoma susceptibility 2 (mouse)Not determined1474394976108395093Mouse
14928314Manh77_mmandible shape 77 (mouse)1476767790110767790Mouse
14747006Mancz12_mmandible centroid size 12 (mouse)1470071977104071977Mouse

Markers in Region
AF053713  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381478,278,230 - 78,278,335UniSTSGRCm38
MGSCv371478,678,037 - 78,678,142UniSTSGRCm37
Celera1475,791,272 - 75,791,377UniSTS
Cytogenetic Map14D3UniSTS
cM Map1445.0UniSTS
Whitehead/MRC_RH14896.96UniSTS
PMC27122P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381478,278,644 - 78,279,040UniSTSGRCm38
MGSCv371478,678,451 - 78,678,847UniSTSGRCm37
Celera1475,791,686 - 75,792,082UniSTS
Cytogenetic Map14D3UniSTS
cM Map1445.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB008426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB022039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB032771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB032772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB036798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF013170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF019048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF053713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC131970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS110679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS110681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000022592   ⟹   ENSMUSP00000022592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1478,514,885 - 78,545,483 (-)Ensembl
GRCm38.p6 Ensembl1478,277,445 - 78,308,043 (-)Ensembl
RefSeq Acc Id: NM_011613   ⟹   NP_035743
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391478,514,886 - 78,545,483 (-)NCBI
GRCm381478,277,446 - 78,308,043 (-)ENTREZGENE
MGSCv371478,677,253 - 78,707,850 (-)RGD
Celera1475,790,488 - 75,821,164 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_035743   ⟸   NM_011613
- UniProtKB: Q9JJK9 (UniProtKB/Swiss-Prot),   Q9JJK8 (UniProtKB/Swiss-Prot),   Q3TWY5 (UniProtKB/Swiss-Prot),   O35306 (UniProtKB/Swiss-Prot),   Q9R1Y0 (UniProtKB/Swiss-Prot),   O35235 (UniProtKB/Swiss-Prot),   Q059M3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000022592   ⟸   ENSMUST00000022592
Protein Domains
THD   TNF family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35235-F1-model_v2 AlphaFold O35235 1-316 view protein structure

Promoters
RGD ID:8683050
Promoter ID:EPDNEW_M19556
Type:multiple initiation site
Name:Tnfsf11_1
Description:Mus musculus tumor necrosis factor superfamily, member 11 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381478,308,043 - 78,308,103EPDNEW
RGD ID:6825495
Promoter ID:MM_KWN:17530
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:ENSMUST00000022592,   ENSMUST00000110858
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361478,707,581 - 78,708,081 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1100089 AgrOrtholog
Ensembl Genes ENSMUSG00000022015 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000022592 ENTREZGENE
  ENSMUST00000022592.8 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TNF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_ligand_10/11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21943 UniProtKB/Swiss-Prot
MGD MGI:1100089 ENTREZGENE
NCBI Gene 21943 ENTREZGENE
PANTHER TUMOR NECROSIS FACTOR FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tnfsf11 PhenoGen
PIRSF TNF10_TNF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TNF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt O35235 ENTREZGENE
  O35306 ENTREZGENE
  Q059M3 ENTREZGENE, UniProtKB/TrEMBL
  Q3TWY5 ENTREZGENE
  Q9JJK8 ENTREZGENE
  Q9JJK9 ENTREZGENE
  Q9R1Y0 ENTREZGENE
  TNF11_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O35306 UniProtKB/Swiss-Prot
  Q3TWY5 UniProtKB/Swiss-Prot
  Q9JJK8 UniProtKB/Swiss-Prot
  Q9JJK9 UniProtKB/Swiss-Prot
  Q9R1Y0 UniProtKB/Swiss-Prot