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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551655
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfsf11
Name: tumor necrosis factor (ligand) superfamily, member 11
Acc ID: CHEBI:28179
Term: benzamide
Definition: An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides.
Chemical ID: MESH:C037689
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfsf11multiple interactionsEXP 6480464CTDbenzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of DCSTAMP mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MAPK1 protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MAPK3 protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFKBIA protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of RELA protein modified form]PMID:29935282
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