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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551655
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfsf11
Name: tumor necrosis factor (ligand) superfamily, member 11
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfsf11increases expressionEXP 6480464CTDEthanol results in increased expression of TNFSF11 mRNA; Ethanol results in increased expression of TNFSF11 proteinPMID:22892342 PMID:24872432 PMID:34755883
Tnfsf11multiple interactionsEXP 6480464CTDGenistein promotes the reaction [Ethanol results in increased expression of TNFSF11 mRNA]; Genistein promotes the reaction [Ethanol results in increased expression of TNFSF11 protein]; Vitamin D inhibits the reaction [Ethanol results in increased expression of TNFSF11 mRNA]PMID:22892342 PMID:24872432
Tnfsf11multiple interactionsISOTnfsf11 (Rattus norvegicus)6480464CTDEthanol promotes the reaction [lead acetate results in increased expression of TNFSF11 protein]PMID:23376407
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