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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551655
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfsf11
Name: tumor necrosis factor (ligand) superfamily, member 11
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfsf11decreases expressionISOTnfsf11 (Rattus norvegicus)6480464CTDNicotine results in decreased expression of TNFSF11 mRNAPMID:29981921
Tnfsf11multiple interactionsISOTnfsf11 (Rattus norvegicus)6480464CTDDihydro-beta-Erythroidine inhibits the reaction [Nicotine results in decreased expression of TNFSF11 mRNA]PMID:29981921
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