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Gene: Atr (ataxia telangiectasia and Rad3 related) Mus musculus
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Symbol: Atr
Name: ataxia telangiectasia and Rad3 related
Description: Exhibits protein kinase activity. Involved in several processes, including DNA damage checkpoint; embryo implantation; and positive regulation of telomere maintenance via telomerase. Localizes to the XY body. Used to study Seckel syndrome. Human ortholog(s) of this gene implicated in Seckel syndrome 1 and pancreatic cancer. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and gonad. Orthologous to human ATR (ATR serine/threonine kinase); PARTICIPATES IN p53 signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH (+)-schisandrin B; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ataxia telangiectasia and Rad3-related protein; serine/threonine-protein kinase ATR
Orthologs:
Homo sapiens (human) : ATR (ATR serine/threonine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atr (ATR serine/threonine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atr (ATR serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ATR (ATR serine/threonine kinase)
Canis lupus familiaris (dog) : ATR (ATR serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atr (ATR serine/threonine kinase)
Sus scrofa (pig) : ATR (ATR serine/threonine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38995,857,597 - 95,953,217 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37995,758,016 - 95,852,063 (+)NCBIGRCm37mm9NCBIm37
Celera995,424,018 - 95,518,128 (+)NCBICelera
Cytogenetic Map9 E3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Atr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557923
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.