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Gene: Atr (ataxia telangiectasia and Rad3 related) Mus musculus
Symbol: Atr
Name: ataxia telangiectasia and Rad3 related
Description: Exhibits protein kinase activity. Involved in several processes, including DNA damage checkpoint; embryo implantation; and positive regulation of telomere maintenance via telomerase. Localizes to the XY body. Used to study Seckel syndrome. Human ortholog(s) of this gene implicated in Seckel syndrome 1 and pancreatic cancer. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and gonad. Orthologous to human ATR (ATR serine/threonine kinase); PARTICIPATES IN p53 signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH (+)-schisandrin B; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ataxia telangiectasia and Rad3-related protein; serine/threonine-protein kinase ATR
Homo sapiens (human) : ATR (ATR serine/threonine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atr (ATR serine/threonine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atr (ATR serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ATR (ATR serine/threonine kinase)
Canis lupus familiaris (dog) : ATR (ATR serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atr (ATR serine/threonine kinase)
Sus scrofa (pig) : ATR (ATR serine/threonine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38995,857,597 - 95,953,217 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37995,758,016 - 95,852,063 (+)NCBIGRCm37mm9NCBIm37
Celera995,424,018 - 95,518,128 (+)NCBICelera
Cytogenetic Map9 E3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557923
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.