Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gata1 (GATA binding protein 1) Mus musculus
Analyze
Symbol: Gata1
Name: GATA binding protein 1
Description: Exhibits several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II transcription factor binding activity. Involved in several processes, including hemopoiesis; regulation of cellular macromolecule biosynthetic process; and regulation of erythrocyte differentiation. Localizes to nucleus. Is expressed in several structures, including alimentary system; central nervous system; ear; early conceptus; and genitourinary system. Used to study myelodysplastic syndrome; myelofibrosis; and thrombocytopenia. Human ortholog(s) of this gene implicated in Down syndrome; X-linked thrombocytopenia with beta-thalassemia; beta thalassemia; and transient myeloproliferative syndrome. Orthologous to human GATA1 (GATA binding protein 1); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: eryf1; erythroid transcription factor; Gata; Gata-1; GATA-binding factor 1; GATA-binding protein 1; Gf-1; NF-E1 DNA-binding protein
Orthologs:
Homo sapiens (human) : GATA1 (GATA binding protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gata1 (GATA binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gata1 (GATA binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GATA1 (GATA binding protein 1)
Canis lupus familiaris (dog) : GATA1 (GATA binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gata1 (GATA binding protein 1)
Sus scrofa (pig) : GATA1 (GATA binding protein 1)
Chlorocebus sabaeus (African green monkey) : GATA1 (GATA binding protein 1)
Heterocephalus glaber (naked mole-rat) : Gata1 (GATA binding protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX7,959,260 - 7,978,071 (-)EnsemblGRCm38mm10GRCm38
GRCm38X7,959,260 - 7,976,663 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X7,536,386 - 7,544,941 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X7,116,219 - 7,124,774 (-)NCBImm8
CeleraX3,501,753 - 3,509,992 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gata1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10621
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.