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Gene: Ep300 (E1A binding protein p300) Mus musculus
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Symbol: Ep300
Name: E1A binding protein p300
Description: Exhibits several functions, including N-acetyltransferase activity; nucleic acid binding activity; and transcription factor binding activity. Predicted to contribute to DNA-binding transcription factor activity. Involved in several processes, including animal organ development; protein acylation; and regulation of transcription, DNA-templated. Localizes to the histone acetyltransferase complex and transcription factor complex. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Rubinstein-Taybi syndrome and congestive heart failure. Is expressed in several structures, including epidermis; heart; intestine epithelium; liver; and lung. Orthologous to human EP300 (E1A binding protein p300); PARTICIPATES IN androgen signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-(2-chloroethyl)-4-methylthiazole; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A430090G16; A730011L11; E1A-associated protein p300; histone acetyltransferase p300; histone butyryltransferase p300; histone crotonyltransferase p300; KAT3B; p300; p300 HAT
Orthologs:
Homo sapiens (human) : EP300 (E1A binding protein p300)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ep300 (E1A binding protein p300)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ep300 (E1A binding protein p300)
Pan paniscus (bonobo/pygmy chimpanzee) : EP300 (E1A binding protein p300)
Canis lupus familiaris (dog) : ZC3H7B (zinc finger CCCH-type containing 7B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ep300 (E1A binding protein p300)
Sus scrofa (pig) : EP300 (E1A binding protein p300)
Chlorocebus sabaeus (African green monkey) : EP300 (E1A binding protein p300)
more info ...
Related Pseudogenes: Gm18256  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1581,585,351 - 81,652,077 (+)Ensembl
GRCm381581,586,209 - 81,652,077 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371581,416,644 - 81,482,507 (+)NCBIGRCm37mm9NCBIm37
MGSCv361581,413,469 - 81,479,332 (+)NCBImm8
Celera1583,704,343 - 83,770,860 (+)NCBICelera
Cytogenetic Map15 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ep300
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552027
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.