Ep300 (E1A binding protein p300) - Rat Genome Database
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Gene: Ep300 (E1A binding protein p300) Mus musculus
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Symbol: Ep300
Name: E1A binding protein p300
RGD ID: 1552027
MGI Page MGI
Description: Is expressed in several structures, including epithelium; heart; lung; nervous system; and skin. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Rubinstein-Taybi syndrome; colorectal cancer; and congestive heart failure. Orthologous to human EP300 (E1A binding protein p300); PARTICIPATES IN androgen signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-(2-chloroethyl)-4-methylthiazole; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A430090G16; A730011L11; E1A-associated protein p300; histone acetyltransferase p300; histone butyryltransferase p300; histone crotonyltransferase p300; KAT3; KAT3B; p30; p300; p300 HAT
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm18256  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,470,329 - 81,536,278 (+)NCBIGRCm39mm39
GRCm39 Ensembl1581,469,552 - 81,536,278 (+)Ensembl
GRCm381581,586,209 - 81,652,077 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,585,351 - 81,652,077 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,416,644 - 81,482,507 (+)NCBIGRCm37mm9NCBIm37
MGSCv361581,413,469 - 81,479,332 (+)NCBImm8
Celera1583,704,343 - 83,770,860 (+)NCBICelera
Cytogenetic Map15E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenoid cystic carcinoma  (ISO)
Agenesis of Corpus Callosum  (ISO)
Alzheimer's disease  (ISO)
Brain Hypoxia  (ISO)
breast carcinoma  (ISO)
Breast Neoplasms  (ISO)
cardiac arrest  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
CHARGE syndrome  (ISO)
clear cell renal cell carcinoma  (ISO)
colon carcinoma  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
congenital diaphragmatic hernia  (ISO)
congestive heart failure  (ISO)
Craniofacial Abnormalities  (ISO)
Developmental Disabilities  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
Dwarfism  (ISO)
Endometrial Neoplasms  (ISO)
Endotoxemia  (ISO)
esophageal carcinoma  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Diabetes Mellitus  (IEP,IMP,ISO)
genetic disease  (ISO)
glomerulonephritis  (ISO)
head and neck squamous cell carcinoma  (ISO)
heart disease  (ISO)
hepatocellular carcinoma  (ISO)
Huntington's disease  (IEP)
Hyperalgesia  (ISO)
hypertension  (ISO)
intellectual disability  (ISO)
Kidney Reperfusion Injury  (ISO)
Lead Poisoning, Nervous System  (ISO)
lung adenocarcinoma  (ISO)
lung small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
medulloblastoma  (ISO)
melanoma  (ISO)
membranoproliferative glomerulonephritis  (ISO)
Menke-Hennekam Syndrome 2  (ISO)
microcephaly  (ISO)
Micrognathism  (ISO)
Multicystic Dysplastic Kidney  (ISO)
Multiple Abnormalities  (ISO)
nephronophthisis-like nephropathy 1  (ISO)
obesity  (ISO)
Optic Nerve Injuries  (ISO)
Painful Neuropathy  (ISO)
prostate cancer  (ISO)
Reperfusion Injury  (ISO)
Retrognathia  (ISO)
Rubinstein-Taybi syndrome  (ISO)
Sepsis  (ISO)
squamous cell carcinoma  (ISO)
Stevens-Johnson syndrome  (ISO)
systemic lupus erythematosus  (IEA)
T-Cell Lymphoma  (ISO)
Thumb Deformity  (ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
type 2 diabetes mellitus  (IEP)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
11-deoxycorticosterone  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3-aminobenzamide  (ISO)
5-(2-chloroethyl)-4-methylthiazole  (EXP)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP)
8-Br-cAMP  (ISO)
aconitine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinyl palmitate  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
amphotericin B  (ISO)
Anacardic acid  (EXP,ISO)
apigenin  (ISO)
apocynin  (ISO)
arsenous acid  (ISO)
berberine  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
butyric acid  (ISO)
cadmium atom  (EXP)
calcitriol  (EXP)
camptothecin  (ISO)
carbon nanotube  (EXP)
casticin  (ISO)
chromium atom  (EXP)
chromium(6+)  (EXP)
cilostazol  (EXP)
cisplatin  (EXP,ISO)
clobetasol  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP)
curcumin  (ISO)
cyproconazole  (ISO)
cyproterone acetate  (ISO)
D-glucose  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibenziodolium  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP,ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (EXP,ISO)
ellagic acid  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP)
etoposide  (ISO)
fisetin  (ISO)
flavone  (ISO)
folic acid  (EXP)
furan  (ISO)
galangin  (ISO)
gallic acid  (ISO)
Garcinol  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glucose  (ISO)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hyaluronic acid  (ISO)
irinotecan  (ISO)
kaempferol  (ISO)
kojic acid  (ISO)
KT 5720  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
LY294002  (ISO)
menadione  (ISO)
miconazole  (EXP,ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
myricetin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
niclosamide  (ISO)
nitrofen  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
omeprazole  (ISO)
oxaliplatin  (ISO)
p-menthan-3-ol  (ISO)
phenylephrine  (ISO)
phlorizin  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP,ISO)
prochloraz  (ISO)
prostaglandin E2  (ISO)
prostaglandin J2  (ISO)
pyrazinecarboxamide  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
SB 203580  (ISO)
scutellarin  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
silicon dioxide  (ISO)
sirtinol  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
streptozocin  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
superoxide  (ISO)
tamoxifen  (ISO)
tetrathiomolybdate(2-)  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
tungsten  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (IMP)
apoptotic process  (ISO,ISS)
B cell differentiation  (IMP)
behavioral defense response  (IMP)
cartilage development  (NAS)
cell differentiation  (IEA)
cellular response to antibiotic  (ISO)
cellular response to cAMP  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to drug  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to mineralocorticoid stimulus  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to trichostatin A  (ISO)
cellular response to UV  (ISO)
circadian rhythm  (IDA)
digestive tract development  (ISO)
face morphogenesis  (IMP)
fat cell differentiation  (IMP)
heart development  (IMP)
histone acetylation  (IBA,IDA,ISO)
histone H2B acetylation  (ISO)
histone H3 acetylation  (ISO)
histone H4 acetylation  (ISO,ISS)
internal peptidyl-lysine acetylation  (ISO)
internal protein amino acid acetylation  (ISO)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  (ISO)
learning or memory  (IMP)
liver development  (ISO)
lung development  (IMP)
macrophage derived foam cell differentiation  (ISO)
megakaryocyte development  (IMP)
memory  (ISO)
multicellular organism growth  (IMP)
N-terminal peptidyl-lysine acetylation  (ISO,ISS)
negative regulation of cell death  (ISO)
negative regulation of cellular metabolic process  (ISO)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
negative regulation of gluconeogenesis  (ISO)
negative regulation of miRNA metabolic process  (ISO)
negative regulation of protein-containing complex assembly  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
peptidyl-lysine acetylation  (ISO)
peptidyl-lysine butyrylation  (IDA,ISO)
peptidyl-lysine crotonylation  (ISO)
peptidyl-lysine propionylation  (ISO)
platelet formation  (IGI,IMP)
positive regulation by host of viral transcription  (ISO)
positive regulation of axon extension  (ISO)
positive regulation of cell death  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cell growth involved in cardiac muscle cell development  (ISO)
positive regulation of cell size  (ISO)
positive regulation of cellular metabolic process  (ISO)
positive regulation of collagen biosynthetic process  (ISO)
positive regulation of DNA binding  (ISO)
positive regulation of DNA-binding transcription factor activity  (IDA,ISO,ISS)
positive regulation of gene expression  (IGI,ISO)
positive regulation of gene expression, epigenetic  (ISO)
positive regulation of glycoprotein biosynthetic process  (ISO)
positive regulation of histone acetylation  (ISO)
positive regulation of muscle atrophy  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of NIK/NF-kappaB signaling  (ISO)
positive regulation of protein acetylation  (ISO)
positive regulation of protein binding  (IDA)
positive regulation of protein import into nucleus  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein secretion  (ISO)
positive regulation of proteolysis  (ISO)
positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding  (ISO)
positive regulation of sarcomere organization  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IGI,ISO)
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response  (IDA)
positive regulation of transcription, DNA-templated  (IBA,IDA)
positive regulation of transforming growth factor beta receptor signaling pathway  (ISO)
positive regulation of translation  (ISO)
protein acetylation  (IDA,ISO)
protein destabilization  (ISO)
protein kinase B signaling  (ISO)
protein stabilization  (IDA)
protein-DNA complex assembly  (ISO)
regulation of androgen receptor signaling pathway  (ISO)
regulation of angiotensin metabolic process  (ISO)
regulation of glycolytic process  (ISO)
regulation of mitochondrion organization  (IMP)
regulation of transcription by RNA polymerase II  (IDA)
regulation of transcription, DNA-templated  (ISO,ISS)
regulation of tubulin deacetylation  (ISO)
response to calcium ion  (ISO)
response to cobalt ion  (ISO)
response to dexamethasone  (ISO)
response to drug  (ISO)
response to estrogen  (ISO)
response to ethanol  (ISO)
response to fatty acid  (ISO)
response to glucose  (ISO)
response to hydrogen peroxide  (ISO)
response to hypoxia  (ISO,ISS)
response to organic cyclic compound  (ISO)
response to retinoic acid  (ISO)
response to tumor necrosis factor  (ISO)
rhythmic process  (IEA)
skeletal muscle tissue development  (IMP)
somitogenesis  (IGI)
swimming  (IMP)
thigmotaxis  (IMP)

Cellular Component

Molecular Function
acetyltransferase activity  (IDA,ISO,ISS)
activating transcription factor binding  (ISO)
androgen receptor binding  (ISO)
antigen binding  (ISO)
beta-catenin binding  (ISO)
bHLH transcription factor binding  (ISO)
chromatin binding  (IDA,ISO)
chromatin DNA binding  (IBA,IDA,ISO)
cis-regulatory region sequence-specific DNA binding  (ISO)
damaged DNA binding  (ISO)
DNA binding  (IDA,ISO,ISS)
glucocorticoid receptor binding  (ISO)
H3 histone acetyltransferase activity  (ISO)
H4 histone acetyltransferase activity  (ISO)
histone acetyltransferase activity  (IBA,IDA,ISO,ISS)
histone butyryltransferase activity  (IDA)
histone crotonyltransferase activity  (ISO)
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor  (ISO)
metal ion binding  (IEA)
mitogen-activated protein kinase binding  (ISO)
NF-kappaB binding  (ISO)
nuclear hormone receptor binding  (ISO)
p53 binding  (IPI,ISO)
peptide butyryltransferase activity  (ISO)
peptide-lysine-N-acetyltransferase activity  (IDA)
peroxisome proliferator activated receptor binding  (ISO)
pre-mRNA intronic binding  (IDA)
promoter-specific chromatin binding  (ISO)
protein antigen binding  (ISO)
protein binding  (IPI,ISO)
protein C-terminus binding  (ISO)
protein kinase binding  (ISO)
protein propionyltransferase activity  (ISO)
protein-containing complex binding  (ISO)
RNA polymerase II activating transcription factor binding  (IPI,ISO)
RNA polymerase II cis-regulatory region sequence-specific DNA binding  (ISO)
RNA polymerase II transcription factor binding  (IBA,IPI)
SMAD binding  (ISO)
STAT family protein binding  (ISO)
transcription coactivator activity  (IBA,IMP,ISO,ISS)
transcription coregulator activity  (IEA)
transcription factor binding  (IPI,ISO)
transferase activity  (IEA)
transferase activity, transferring acyl groups  (ISO)
zinc ion binding  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adaptive immunity  (IAGP)
abnormal atrioventricular septum morphology  (IAGP)
abnormal B cell differentiation  (IAGP)
abnormal cell physiology  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal epicardium morphology  (IAGP)
abnormal erythrocyte morphology  (IAGP)
abnormal facial morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart valve morphology  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal intestinal epithelium morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal megakaryocyte progenitor cell morphology  (IAGP)
abnormal muscle fiber morphology  (IAGP)
abnormal muscle morphology  (IAGP)
abnormal myogenesis  (IAGP)
abnormal platelet morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal small intestinal villus morphology  (IAGP)
abnormal small intestine morphology  (IAGP)
abnormal spleen marginal zone macrophage morphology  (IAGP)
abnormal T cell number  (IAGP)
abnormal transitional stage B cell morphology  (IAGP)
abnormal tumor incidence  (IAGP)
abnormal tumor susceptibility  (IAGP)
abnormal vasculogenesis  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
absent trabeculae carneae  (IAGP)
anemia  (IAGP)
anisocytosis  (IAGP)
arteritis  (IAGP)
atrial septal defect  (IAGP)
cyanosis  (IAGP)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased body size  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased embryo size  (IAGP)
decreased eosinophil cell number  (IAGP)
decreased fibroblast proliferation  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased marginal zone B cell number  (IAGP)
decreased single-positive T cell number  (IAGP)
decreased skeletal muscle fiber size  (IAGP)
decreased thymocyte number  (IAGP)
delayed heart development  (IAGP)
early cellular replicative senescence  (IAGP)
edema  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enlarged heart  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
exencephaly  (IAGP)
extramedullary hematopoiesis  (IAGP)
glomerulonephritis  (IAGP)
hemorrhage  (IAGP)
incomplete embryo turning  (IAGP)
incomplete somite formation  (IAGP)
increased activated T cell number  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased B cell apoptosis  (IAGP)
increased B cell number  (IAGP)
increased double-negative T cell number  (IAGP)
increased double-positive T cell number  (IAGP)
increased eosinophil cell number  (IAGP)
increased IgG2b level  (IAGP)
increased immunoglobulin level  (IAGP)
increased megakaryocyte cell number  (IAGP)
increased spleen weight  (IAGP)
increased susceptibility to systemic lupus erythematosus  (IAGP)
intermingled spleen red and white pulp  (IAGP)
internal hemorrhage  (IAGP)
kidney inflammation  (IAGP)
kinked neural tube  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
microphthalmia  (IAGP)
myocardium hypoplasia  (IAGP)
no abnormal phenotype detected  (IEA)
open neural tube  (IAGP)
pericardial effusion  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
renal fibrosis  (IAGP)
renal glomerular protein deposits  (IAGP)
respiratory failure  (IAGP)
small thymus  (IAGP)
thin myocardium  (IAGP)
thin ventricle myocardium compact layer  (IAGP)
thin ventricular wall  (IAGP)
thrombocytosis  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
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28. MGD data from the GO Consortium
29. MGD IEA
30. Morimoto T, etal., J Clin Invest. 2008 Mar;118(3):868-78.
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32. OMIM Disease Annotation Pipeline
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34. Pipeline to import KEGG annotations from KEGG into RGD
35. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
36. Prajapati KD, etal., Neurol Res. 2012 Jan;34(1):25-31. doi: 10.1179/1743132811Y.0000000052.
37. RGD automated import pipeline
38. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
39. RGD automated import pipeline for gene-chemical interactions
40. Roelfsema JH, etal., Am J Hum Genet. 2005 Apr;76(4):572-80. Epub 2005 Feb 10.
41. Semenza GL Physiology (Bethesda). 2009 Apr;24:97-106.
42. Takahashi H, etal., Pediatr Surg Int. 2014 Apr;30(4):431-5. doi: 10.1007/s00383-014-3466-1.
43. Tan XL, etal., Brain Res. 2009 Feb 13;1254:1-9. Epub 2008 Dec 10.
44. Wang C, etal., Diabetes Metab Res Rev. 2012 May;28(4):329-37. doi: 10.1002/dmrr.2279.
45. Wei JQ, etal., Circulation. 2008 Aug 26;118(9):934-46. Epub 2008 Aug 12.
46. Wong HK, etal., Hum Mol Genet. 2013 Aug 1;22(15):3077-92. doi: 10.1093/hmg/ddt164. Epub 2013 Apr 11.
47. Xu B, etal., Diabetes Metab Res Rev. 2008 Jul-Aug;24(5):404-12.
48. Yanazume T, etal., Mol Cell Biol. 2003 May;23(10):3593-606.
49. Yao TP, etal., Cell 1998 May 1;93(3):361-72.
50. Zhang J, etal., FASEB J. 2014 Mar;28(3):1511-25. doi: 10.1096/fj.13-242693. Epub 2013 Dec 16.
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52. Zhu XY, etal., Mol Pain. 2012 Nov 23;8:84. doi: 10.1186/1744-8069-8-84.
Additional References at PubMed
PMID:7684738   PMID:8004670   PMID:8855229   PMID:9194565   PMID:9512516   PMID:9659901   PMID:9742083   PMID:10066817   PMID:10189358   PMID:10205054   PMID:10327051   PMID:10349636  
PMID:10518217   PMID:10593900   PMID:10610021   PMID:10706102   PMID:10906457   PMID:11042159   PMID:11076796   PMID:11076861   PMID:11087842   PMID:11096067   PMID:11115394   PMID:11217851  
PMID:11331592   PMID:11481322   PMID:11850820   PMID:11867645   PMID:11884404   PMID:11896584   PMID:11948408   PMID:11963968   PMID:11994297   PMID:12040021   PMID:12384703   PMID:12391150  
PMID:12397173   PMID:12435739   PMID:12464179   PMID:12466851   PMID:12477932   PMID:12488456   PMID:12493762   PMID:12520002   PMID:12586840   PMID:12665587   PMID:12672795   PMID:12690203  
PMID:12709428   PMID:12904583   PMID:12960163   PMID:14517255   PMID:14517256   PMID:14555661   PMID:14610273   PMID:14635047   PMID:14645221   PMID:14662860   PMID:14691545   PMID:14742445  
PMID:14749395   PMID:14752096   PMID:14975762   PMID:14976201   PMID:14980222   PMID:15024082   PMID:15100295   PMID:15117818   PMID:15189737   PMID:15199055   PMID:15261140   PMID:15289617  
PMID:15308641   PMID:15485860   PMID:15601857   PMID:15601870   PMID:15616592   PMID:15632193   PMID:15641773   PMID:15681609   PMID:15691758   PMID:15808511   PMID:15860545   PMID:15878863  
PMID:15937931   PMID:15951563   PMID:16141072   PMID:16141073   PMID:16166090   PMID:16210620   PMID:16237459   PMID:16245309   PMID:16325578   PMID:16424387   PMID:16428436   PMID:16461841  
PMID:16582105   PMID:16596650   PMID:16619037   PMID:16702405   PMID:16704373   PMID:16801560   PMID:16809611   PMID:16890162   PMID:17111365   PMID:17150957   PMID:17220375   PMID:17467007  
PMID:17478422   PMID:17513743   PMID:17525731   PMID:17559085   PMID:17562868   PMID:17591690   PMID:17641689   PMID:17656371   PMID:17761541   PMID:17869641   PMID:18003640   PMID:18022353  
PMID:18241125   PMID:18268343   PMID:18330926   PMID:18458062   PMID:18458156   PMID:18486321   PMID:18552833   PMID:18605988   PMID:18684867   PMID:18710950   PMID:18799693   PMID:18842595  
PMID:19146829   PMID:19150979   PMID:19212405   PMID:19252086   PMID:19252138   PMID:19266485   PMID:19272189   PMID:19273602   PMID:19324970   PMID:19359245   PMID:19385047   PMID:19433445  
PMID:19487584   PMID:19515997   PMID:19524524   PMID:19591226   PMID:19598128   PMID:19651603   PMID:19723804   PMID:19729597   PMID:19822209   PMID:19822904   PMID:19828133   PMID:19883617  
PMID:19922678   PMID:19949111   PMID:20081228   PMID:20107328   PMID:20206554   PMID:20211142   PMID:20810990   PMID:20930143   PMID:20955178   PMID:21057544   PMID:21115812   PMID:21169561  
PMID:21179216   PMID:21245169   PMID:21257959   PMID:21267068   PMID:21326203   PMID:21356387   PMID:21357426   PMID:21389279   PMID:21454709   PMID:21498542   PMID:21555743   PMID:21556048  
PMID:21596989   PMID:21677750   PMID:21680747   PMID:21722948   PMID:21803292   PMID:21847097   PMID:21873635   PMID:22013068   PMID:22086955   PMID:22094330   PMID:22179676   PMID:22384255  
PMID:22415975   PMID:22523253   PMID:22579476   PMID:22666487   PMID:22677942   PMID:22780989   PMID:22815486   PMID:23285212   PMID:23297412   PMID:23303459   PMID:23475960   PMID:23618903  
PMID:23752591   PMID:23770612   PMID:23922782   PMID:23955711   PMID:23999430   PMID:24038357   PMID:24089570   PMID:24207025   PMID:24216764   PMID:24340053   PMID:24363063   PMID:24379407  
PMID:24480624   PMID:24522976   PMID:24565863   PMID:24586743   PMID:24596419   PMID:24648406   PMID:24759103   PMID:24796935   PMID:24835996   PMID:24852146   PMID:24880616   PMID:25051175  
PMID:25088465   PMID:25117711   PMID:25154413   PMID:25200183   PMID:25240203   PMID:25335984   PMID:25446101   PMID:26100016   PMID:26180185   PMID:26244796   PMID:26327117   PMID:26372908  
PMID:26390242   PMID:26695438   PMID:26712218   PMID:26718496   PMID:26859354   PMID:26899911   PMID:26921506   PMID:27105113   PMID:27118681   PMID:27477692   PMID:27585400   PMID:27635759  
PMID:27720608   PMID:27803164   PMID:27881875   PMID:27913583   PMID:28103279   PMID:28121289   PMID:28291835   PMID:28398509   PMID:28424251   PMID:28652407   PMID:28732206   PMID:28743992  
PMID:28831000   PMID:29141987   PMID:29145650   PMID:29184203   PMID:29217654   PMID:29454793   PMID:29789539   PMID:30201979   PMID:30546087   PMID:30655546   PMID:30705122   PMID:30887098  
PMID:30888860   PMID:30953353   PMID:31519498   PMID:31536903   PMID:31600191   PMID:32325033   PMID:32444594   PMID:32576962   PMID:32690000   PMID:32791154  


Genomics

Comparative Map Data
Ep300
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,470,329 - 81,536,278 (+)NCBIGRCm39mm39
GRCm39 Ensembl1581,469,552 - 81,536,278 (+)Ensembl
GRCm381581,586,209 - 81,652,077 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,585,351 - 81,652,077 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,416,644 - 81,482,507 (+)NCBIGRCm37mm9NCBIm37
MGSCv361581,413,469 - 81,479,332 (+)NCBImm8
Celera1583,704,343 - 83,770,860 (+)NCBICelera
Cytogenetic Map15E1NCBI
EP300
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,092,592 - 41,180,077 (+)EnsemblGRCh38hg38GRCh38
GRCh382241,092,592 - 41,180,077 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372241,488,596 - 41,576,081 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,818,553 - 39,906,024 (+)NCBINCBI36hg18NCBI36
Build 342239,813,106 - 39,900,578NCBI
Celera2225,294,977 - 25,382,428 (+)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,453,007 - 24,540,433 (+)NCBIHuRef
CHM1_12241,448,337 - 41,535,740 (+)NCBICHM1_1
Ep300
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27113,108,476 - 113,178,529 (+)NCBI
Rnor_6.0 Ensembl7122,818,975 - 122,861,296 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07122,818,194 - 122,889,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07122,792,742 - 122,863,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,938,507 - 120,008,886 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17119,972,736 - 120,000,026 (+)NCBI
Celera7109,426,729 - 109,497,522 (+)NCBICelera
Cytogenetic Map7q34NCBI
Ep300
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,648,339 - 26,727,933 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,647,553 - 26,727,875 (+)NCBIChiLan1.0ChiLan1.0
EP300
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12240,079,214 - 40,168,936 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2240,079,503 - 40,168,604 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02221,986,467 - 22,076,921 (+)NCBIMhudiblu_PPA_v0panPan3
ZC3H7B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1023,884,981 - 23,920,131 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11023,882,379 - 23,944,850 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ep300
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936492696,982 - 778,132 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EP300
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,311,171 - 7,393,760 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,311,165 - 7,394,515 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,574,025 - 4,656,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EP300
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11923,634,132 - 23,726,095 (+)NCBI
ChlSab1.1 Ensembl1923,634,571 - 23,724,979 (+)Ensembl

Position Markers
Ep300  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381581,601,330 - 81,601,447UniSTSGRCm38
MGSCv371581,431,760 - 81,431,877UniSTSGRCm37
Celera1583,719,601 - 83,719,718UniSTS
Cytogenetic Map15E1UniSTS
cM Map15 UniSTS
EP300_8165  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381581,650,945 - 81,651,743UniSTSGRCm38
MGSCv371581,481,375 - 81,482,173UniSTSGRCm37
Celera1583,769,728 - 83,770,526UniSTS
Cytogenetic Map15E1UniSTS
RH136048  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381581,651,528 - 81,651,726UniSTSGRCm38
GRCm38744,646,930 - 44,647,130UniSTSGRCm38
MGSCv37751,902,300 - 51,902,500UniSTSGRCm37
MGSCv371581,481,958 - 81,482,156UniSTSGRCm37
Celera1583,770,311 - 83,770,509UniSTS
Celera740,097,071 - 40,097,270UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map15E1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15610000086800000Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156100000100900000Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15690000084700000Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402117102988123Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800000102100000Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578270103517472Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800000086800000Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154230000095600000Mouse
1300644Fob3_mF-line obesity QTL 3 (mouse)11.3Not determined154414443889377036Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154850000098500000Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548500000101800000Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154859351382593647Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155128885985288984Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155154651285546662Mouse
10412067Pain2_mpain 2 (mouse)Not determined155177349085773777Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155181398385822600Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155193466685934802Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155370000089700000Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155491728088917280Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556323312103517472Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155690000087800000Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155724515691245304Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155724515691245304Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156170000095700000Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156327970297279794Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564434485103517472Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156492762598927745Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156545237799456827Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156564117599641298Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567386497101386646Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570461452104043685Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570465070104043685Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570465070104043685Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572498466104043685Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573545941104043685Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157422869182789955Mouse
1301472Pain1_mpain 1 (mouse)Not determined157544899790928982Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577629711104043685Mouse
15092080Igly7_mIgG glycosylation 7, GP10 (mouse)157791071982789955Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78716903102993272Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578716903102993272Mouse
14928306Manh79_mmandible shape 79 (mouse)1578949676104043685Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1579000000104043685Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579265530104043685Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined80011059104043685Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580415753104043685Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580987052104043685Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580987052104043685Mouse
25394540Skmw82_mskeletal muscle weight 82, soleus (mouse)158155023581786938Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir132mmu-miR-132-5pMirecordsexternal_infoNANA21118894

Predicted Target Of
Summary Value
Count of predictions:222
Count of miRNA genes:195
Interacting mature miRNAs:201
Transcripts:ENSMUST00000068387
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_177821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA175990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AA269399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC102262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC160528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF071430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI020056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI049018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC126890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG147550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM070050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM947476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ443767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU055016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU058047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU701221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY065998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY076076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY759831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA324548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01119843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01120693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB245766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB520673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD348567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN535246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN536119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN537190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN708842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000068387   ⟹   ENSMUSP00000066789
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,585,397 - 81,652,077 (+)Ensembl
RefSeq Acc Id: ENSMUST00000185375
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,585,351 - 81,588,347 (+)Ensembl
RefSeq Acc Id: ENSMUST00000185967   ⟹   ENSMUSP00000139889
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,613,315 - 81,623,518 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187776
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,636,148 - 81,644,605 (+)Ensembl
RefSeq Acc Id: ENSMUST00000189338
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,586,220 - 81,624,218 (+)Ensembl
RefSeq Acc Id: ENSMUST00000190035
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,613,333 - 81,616,542 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205816
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,633,979 - 81,640,529 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206431
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,644,850 - 81,649,182 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206833   ⟹   ENSMUSP00000146251
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,627,425 - 81,627,863 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206936   ⟹   ENSMUSP00000145639
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1581,621,062 - 81,626,453 (+)Ensembl
RefSeq Acc Id: NM_177821   ⟹   NP_808489
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,470,415 - 81,536,278 (+)NCBI
GRCm381581,586,214 - 81,652,077 (+)ENTREZGENE
MGSCv371581,416,644 - 81,482,507 (+)RGD
Celera1583,704,343 - 83,770,860 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006521089   ⟹   XP_006521152
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,470,329 - 81,536,273 (+)NCBI
GRCm381581,586,209 - 81,652,072 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006521090   ⟹   XP_006521153
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,470,329 - 81,536,273 (+)NCBI
GRCm381581,586,209 - 81,652,072 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006521091   ⟹   XP_006521154
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,470,455 - 81,536,273 (+)NCBI
GRCm381581,586,416 - 81,652,072 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030248611   ⟹   XP_030104471
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,470,329 - 81,536,273 (+)NCBI
GRCm381581,586,209 - 81,652,072 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_808489   ⟸   NM_177821
- UniProtKB: B2RWS6 (UniProtKB/Swiss-Prot),   Q8BJ14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521152   ⟸   XM_006521089
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006521153   ⟸   XM_006521090
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006521154   ⟸   XM_006521091
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_030104471   ⟸   XM_030248611
- Peptide Label: isoform X3
RefSeq Acc Id: ENSMUSP00000145639   ⟸   ENSMUST00000206936
RefSeq Acc Id: ENSMUSP00000146251   ⟸   ENSMUST00000206833
RefSeq Acc Id: ENSMUSP00000066789   ⟸   ENSMUST00000068387
RefSeq Acc Id: ENSMUSP00000139889   ⟸   ENSMUST00000185967
Protein Domains
Bromo   CBP/p300-type HAT   KIX   TAZ-type

Promoters
RGD ID:6825988
Promoter ID:MM_KWN:19157
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000116877,   NM_177821,   UC007WWR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361581,415,786 - 81,416,917 (+)MPROMDB
RGD ID:6825981
Promoter ID:MM_KWN:19160
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour
Transcripts:UC007WWT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361581,466,546 - 81,467,046 (+)MPROMDB
RGD ID:8684444
Promoter ID:EPDNEW_M20252
Type:initiation region
Name:Ep300_1
Description:Mus musculus E1A binding protein p300 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381581,586,212 - 81,586,272EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1276116 AgrOrtholog
Ensembl Genes ENSMUSG00000055024 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000066789 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000139889 UniProtKB/TrEMBL
  ENSMUSP00000145639 UniProtKB/TrEMBL
  ENSMUSP00000146251 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000068387 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000185967 UniProtKB/TrEMBL
  ENSMUST00000206833 UniProtKB/TrEMBL
  ENSMUST00000206936 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1630.10 UniProtKB/Swiss-Prot
  1.10.246.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.1020.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.920.10 UniProtKB/Swiss-Prot
  2.10.110.40 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
  3.30.60.90 UniProtKB/Swiss-Prot
InterPro Bromodomain UniProtKB/Swiss-Prot
  Bromodomain-like_sf UniProtKB/Swiss-Prot
  Bromodomain_CS UniProtKB/Swiss-Prot
  CBP_P300_HAT UniProtKB/Swiss-Prot
  Histone_AcTrfase_Rtt109/CBP UniProtKB/Swiss-Prot
  KIX_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KIX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuc_rcpt_coact UniProtKB/Swiss-Prot
  Nuc_rcpt_coact_CREBbp UniProtKB/Swiss-Prot
  Nuc_rcpt_coact_CREBbp_sf UniProtKB/Swiss-Prot
  RING_CBP-p300 UniProtKB/Swiss-Prot
  RING_CBP-p300_sf UniProtKB/Swiss-Prot
  TAZ_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_TAZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_ZZ UniProtKB/Swiss-Prot
  Znf_ZZ_sf UniProtKB/Swiss-Prot
KEGG Report mmu:328572 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1276116 ENTREZGENE
NCBI Gene 328572 ENTREZGENE
Pfam Bromodomain UniProtKB/Swiss-Prot
  Creb_binding UniProtKB/Swiss-Prot
  DUF902 UniProtKB/Swiss-Prot
  HAT_KAT11 UniProtKB/Swiss-Prot
  KIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00569 UniProtKB/Swiss-Prot
  zf-TAZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB EP300 RGD
PhenoGen Ep300 PhenoGen
PRINTS BROMODOMAIN UniProtKB/Swiss-Prot
PROSITE BROMODOMAIN_1 UniProtKB/Swiss-Prot
  BROMODOMAIN_2 UniProtKB/Swiss-Prot
  CBP_P300_HAT UniProtKB/Swiss-Prot
  KIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_TAZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_ZZ_1 UniProtKB/Swiss-Prot
  ZF_ZZ_2 UniProtKB/Swiss-Prot
SMART BROMO UniProtKB/Swiss-Prot
  KAT11 UniProtKB/Swiss-Prot
  ZnF_TAZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_ZZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47040 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47370 UniProtKB/Swiss-Prot
  SSF57933 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF69125 UniProtKB/Swiss-Prot
UniProt A0A087WPR8_MOUSE UniProtKB/TrEMBL
  A0A0U1RNN6_MOUSE UniProtKB/TrEMBL
  A0A0U1RQ52_MOUSE UniProtKB/TrEMBL
  B2RWS6 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3USJ1_MOUSE UniProtKB/TrEMBL
  Q8BJ14 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9PYJ8 UniProtKB/Swiss-Prot