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Gene: Serpinh1 (serine (or cysteine) peptidase inhibitor, clade H, member 1) Mus musculus
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Symbol: Serpinh1
Name: serine (or cysteine) peptidase inhibitor, clade H, member 1
Description: Exhibits unfolded protein binding activity. Involved in several processes, including chondrocyte development involved in endochondral bone morphogenesis; collagen biosynthetic process; and collagen fibril organization. Localizes to endoplasmic reticulum. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; lower jaw tooth; and skeleton. Used to study osteogenesis imperfecta type 10. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 10 and preterm premature rupture of the membranes. Orthologous to human SERPINH1 (serpin family H member 1); INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 47 kDa heat shock protein; BERF-1; beta enolase repressor factor 1; Cbp1; Cbp2; collagen binding protein 1; collagen-binding protein; colligin; gp46; Hsp47; J6; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2; serine (or cysteine) proteinase inhibitor, clade H, member 1; serine (or cysteine) proteinase inhibitor, clade H, member 2; serine protease inhibitor J6; serpin H1; Serpinh2
Orthologs:
Homo sapiens (human) : SERPINH1 (serpin family H member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Serpinh1 (serpin family H member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinh1 (serpin family H member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINH1 (serpin family H member 1)
Canis lupus familiaris (dog) : SERPINH1 (serpin family H member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinh1 (serpin family H member 1)
Sus scrofa (pig) : SERPINH1 (serpin family H member 1)
Chlorocebus sabaeus (African green monkey) : SERPINH1 (serpin family H member 1)
Heterocephalus glaber (naked mole-rat) : Serpinh1 (serpin family H member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl799,345,376 - 99,353,239 (-)EnsemblGRCm38mm10GRCm38
GRCm38799,345,375 - 99,353,239 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377106,493,885 - 106,501,749 (-)NCBIGRCm37mm9NCBIm37
MGSCv36799,219,459 - 99,227,179 (-)NCBImm8
Celera799,670,192 - 99,678,104 (-)NCBICelera
Cytogenetic Map7E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Serpinh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737440
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.