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Gene: Sp1 (trans-acting transcription factor 1) Mus musculus
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Symbol: Sp1
Name: trans-acting transcription factor 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; embryo development; and mRNA transcription by RNA polymerase II. Localizes to nuclear chromatin. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; gut epithelium; and sensory organ. Orthologous to human SP1 (Sp1 transcription factor); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; INTERACTS WITH (R)-lipoic acid; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110003E12Rik; AA450830; AI845540; Sp1-1; specificity protein 1; transcription factor Sp1
Orthologs:
Homo sapiens (human) : SP1 (Sp1 transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sp1 (Sp1 transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sp1 (Sp1 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SP1 (Sp1 transcription factor)
Canis lupus familiaris (dog) : SP1 (Sp1 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sp1 (Sp1 transcription factor)
Sus scrofa (pig) : SP1 (Sp1 transcription factor)
Chlorocebus sabaeus (African green monkey) : SP1 (Sp1 transcription factor)
Heterocephalus glaber (naked mole-rat) : Sp1 (Sp1 transcription factor)
more info ...
Related Pseudogenes: Gm18697  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl15102,406,143 - 102,436,404 (+)EnsemblGRCm38mm10GRCm38
GRCm3815102,406,316 - 102,436,404 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3715102,236,747 - 102,266,835 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615102,234,362 - 102,260,713 (+)NCBImm8
Celera15104,563,277 - 104,594,207 (+)NCBICelera
Cytogenetic Map15F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11334
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.