Sp1 (Sp1 transcription factor) - Rat Genome Database

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Gene: Sp1 (Sp1 transcription factor) Ictidomys tridecemlineatus
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Symbol: Sp1
Name: Sp1 transcription factor
RGD ID: 12479750
Description: ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellular response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN euchromatin (ortholog); protein-DNA complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor Sp1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,467,059 - 62,509,967 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,655,349 - 10,693,042 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,655,116 - 10,693,025 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Sp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,467,059 - 62,509,967 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,655,349 - 10,693,042 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,655,116 - 10,693,025 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,380,176 - 53,416,446 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,380,176 - 53,416,446 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,773,960 - 53,810,230 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,060,246 - 52,096,497 (+)NCBINCBI36Build 36hg18NCBI36
Build 341252,060,245 - 52,096,491NCBI
Celera1253,423,138 - 53,460,427 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,814,656 - 50,850,614 (+)NCBIHuRef
CHM1_11253,741,140 - 53,777,425 (+)NCBICHM1_1
T2T-CHM13v2.01253,346,223 - 53,382,489 (+)NCBIT2T-CHM13v2.0
Sp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,314,751 - 102,344,839 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,314,578 - 102,344,839 (+)EnsemblGRCm39 Ensembl
GRCm3815102,406,316 - 102,436,404 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,406,143 - 102,436,404 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,236,747 - 102,266,835 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,234,362 - 102,260,713 (+)NCBIMGSCv36mm8
Celera15104,563,277 - 104,594,207 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.55NCBI
Sp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,419,864 - 135,450,513 (+)NCBIGRCr8
mRatBN7.27133,541,302 - 133,571,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,541,491 - 133,571,961 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,298,300 - 135,327,653 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,527,694 - 137,557,048 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,513,816 - 137,543,172 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07144,014,173 - 144,044,635 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,014,173 - 144,044,629 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,805,281 - 141,836,504 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,164,180 - 141,194,509 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,240,616 - 141,265,690 (+)NCBI
Celera7129,968,890 - 129,999,257 (+)NCBICelera
RH 3.4 Map71062.1RGD
Cytogenetic Map7q36NCBI
Sp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458644,378 - 677,441 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458644,435 - 677,360 (+)NCBIChiLan1.0ChiLan1.0
SP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,770,223 - 40,809,774 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,766,986 - 40,806,525 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,338,492 - 35,374,462 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,122,583 - 36,158,356 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,127,681 - 36,158,356 (-)Ensemblpanpan1.1panPan2
SP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,802,587 - 1,861,187 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,805,184 - 1,847,226 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,404,740 - 44,448,820 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,804,038 - 1,848,490 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,804,038 - 1,848,385 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,823,470 - 1,867,184 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,807,708 - 1,852,315 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,805,663 - 44,849,851 (+)NCBIUU_Cfam_GSD_1.0
SP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,588,758 - 18,630,089 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,588,763 - 18,633,177 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2519,024,941 - 19,070,820 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,484,459 - 49,516,941 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,484,518 - 49,512,541 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,540,987 - 196,574,325 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249041,475,664 - 1,507,588 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000005921   ⟹   ENSSTOP00000005298
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493651210,655,349 - 10,692,617 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000026430   ⟹   ENSSTOP00000023331
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493651210,655,461 - 10,693,042 (+)Ensembl
RefSeq Acc Id: XM_040280567   ⟹   XP_040136501
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494562,467,059 - 62,509,967 (-)NCBI
RefSeq Acc Id: XM_040280568   ⟹   XP_040136502
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494562,467,059 - 62,509,874 (-)NCBI
RefSeq Acc Id: XM_040280569   ⟹   XP_040136503
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494562,467,059 - 62,509,967 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040136501 (Get FASTA)   NCBI Sequence Viewer  
  XP_040136502 (Get FASTA)   NCBI Sequence Viewer  
  XP_040136503 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000005298.3
  ENSSTOP00000023331.2
GenBank Protein KAG3291845 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040136503   ⟸   XM_040280569
- Peptide Label: isoform X2
- UniProtKB: I3NG34 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040136501   ⟸   XM_040280567
- Peptide Label: isoform X1
- UniProtKB: I3NG34 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040136502   ⟸   XM_040280568
- Peptide Label: isoform X1
- UniProtKB: I3NG34 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000005298   ⟸   ENSSTOT00000005921
Ensembl Acc Id: ENSSTOP00000023331   ⟸   ENSSTOT00000026430
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005928 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005921.3 UniProtKB/TrEMBL
  ENSSTOT00000026430.2 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Sp1 ENTREZGENE
PANTHER KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR SP1 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt I3M6Y3_ICTTR UniProtKB/TrEMBL
  I3NG34 ENTREZGENE, UniProtKB/TrEMBL