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Gene: Tet1 (tet methylcytosine dioxygenase 1) Mus musculus
Symbol: Tet1
Name: tet methylcytosine dioxygenase 1
Description: ENCODES a protein that exhibits methylcytosine dioxygenase activity; DNA binding (ortholog); iron ion binding (ortholog); INVOLVED IN DNA demethylation; inner cell mass cell differentiation; positive regulation of transcription by RNA polymerase II; PARTICIPATES IN DNA modification pathway; ASSOCIATED WITH abnormal DNA methylation; abnormal double-strand DNA break repair; abnormal embryo development; ASSOCIATED WITH autism spectrum disorder (ortholog); hepatocellular carcinoma (ortholog); FOUND IN nucleus; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 5-(hydroxymethyl)cytosine; 5-methylcytosine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2510010B09Rik; AA517754; BB001228; CXXC finger 6; CXXC-type zinc finger protein 6; Cxxc6; D10Ertd17e; expressed sequence BB001228; LCX; methylcytosine dioxygenase TET1; mKIAA1676; ten-eleven translocation 1 gene protein homolog; tet oncogene 1
Homo sapiens (human) : TET1 (tet methylcytosine dioxygenase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tet1 (tet methylcytosine dioxygenase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tet1 (tet methylcytosine dioxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TET1 (tet methylcytosine dioxygenase 1)
Canis lupus familiaris (dog) : TET1 (tet methylcytosine dioxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tet1 (tet methylcytosine dioxygenase 1)
Sus scrofa (pig) : TET1 (tet methylcytosine dioxygenase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381062,804,570 - 62,887,469 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371062,267,318 - 62,342,762 (-)NCBIGRCm37mm9NCBIm37
MGSCv361062,207,059 - 62,275,371 (-)NCBImm8
Celera1063,905,755 - 63,981,217 (-)NCBICelera
Cytogenetic Map10 B4NCBI
cM Map1032.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tet1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322210
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.