Lyzl4 (lysozyme-like 4) - Rat Genome Database
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Gene: Lyzl4 (lysozyme-like 4) Mus musculus
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Symbol: Lyzl4
Name: lysozyme-like 4
RGD ID: 1553873
MGI Page MGI
Description: Predicted to have lysozyme activity. Involved in fertilization. Localizes to acrosomal vesicle; extracellular space; and sperm flagellum. Is expressed in craniocervical region bone; ganglia; medulla oblongata basal plate mantle layer; and stomach. Orthologous to human LYZL4 (lysozyme like 4); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810009N24Rik; AI504271; LYC; Lyc4; lysozyme a; lysozyme-4; lysozyme-like protein 4; Lyza
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,406,907 - 121,471,187 (-)NCBIGRCm39mm39
GRCm389121,577,841 - 121,642,121 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,577,843 - 121,642,096 (-)EnsemblGRCm38mm10GRCm38
MGSCv379121,486,961 - 121,550,684 (-)NCBIGRCm37mm9NCBIm37
MGSCv369121,426,541 - 121,490,264 (-)NCBImm8
Celera9122,047,977 - 122,114,890 (-)NCBICelera
Cytogenetic Map9F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
lysozyme activity  (IEA,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21444326   PMID:21677750   PMID:21873635   PMID:27357688  


Genomics

Comparative Map Data
Lyzl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,406,907 - 121,471,187 (-)NCBIGRCm39mm39
GRCm389121,577,841 - 121,642,121 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,577,843 - 121,642,096 (-)EnsemblGRCm38mm10GRCm38
MGSCv379121,486,961 - 121,550,684 (-)NCBIGRCm37mm9NCBIm37
MGSCv369121,426,541 - 121,490,264 (-)NCBImm8
Celera9122,047,977 - 122,114,890 (-)NCBICelera
Cytogenetic Map9F4NCBI
LYZL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl342,397,083 - 42,410,610 (-)EnsemblGRCh38hg38GRCh38
GRCh38342,360,766 - 42,411,794 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37342,438,575 - 42,452,125 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,413,579 - 42,427,069 (-)NCBINCBI36hg18NCBI36
Build 34342,413,578 - 42,427,069NCBI
Celera342,378,992 - 42,392,482 (-)NCBI
Cytogenetic Map3p22.1NCBI
HuRef342,482,777 - 42,496,267 (-)NCBIHuRef
CHM1_1342,389,878 - 42,403,392 (-)NCBICHM1_1
Lyzl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08130,219,984 - 130,228,066 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,220,018 - 130,224,444 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08129,406,646 - 129,414,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48126,588,240 - 126,592,666 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18126,607,941 - 126,621,696 (-)NCBI
Celera8120,383,010 - 120,387,460 (-)NCBICelera
Cytogenetic Map8q32NCBI
Lyzl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542028,336,162 - 28,344,635 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542028,333,984 - 28,344,180 (+)NCBIChiLan1.0ChiLan1.0
LYZL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1342,565,535 - 42,579,033 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl342,565,535 - 42,579,033 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0342,302,237 - 42,378,700 (-)NCBIMhudiblu_PPA_v0panPan3
LYZL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2311,526,697 - 11,540,554 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12311,526,560 - 11,540,724 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Lyzl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366952,668,444 - 2,674,605 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYZL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1325,987,939 - 25,995,115 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11325,987,662 - 25,992,607 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21328,656,765 - 28,664,020 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LYZL4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,803,258 - 3,855,368 (-)NCBI
Lyzl4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473077,220,928 - 77,224,946 (+)NCBI

Position Markers
UniSTS:236287  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389121,577,865 - 121,578,072UniSTSGRCm38
MGSCv379121,486,983 - 121,487,190UniSTSGRCm37
Celera9122,047,999 - 122,048,206UniSTS
Cytogenetic Map9F4UniSTS
AI504271  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389121,577,883 - 121,577,978UniSTSGRCm38
MGSCv379121,487,001 - 121,487,096UniSTSGRCm37
Celera9122,048,017 - 122,048,112UniSTS
Cytogenetic Map9F4UniSTS
Whitehead/MRC_RH91233.41UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:548
Count of miRNA genes:261
Interacting mature miRNAs:273
Transcripts:ENSMUST00000077706, ENSMUST00000120918, ENSMUST00000125075
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000077706   ⟹   ENSMUSP00000076887
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,577,843 - 121,641,566 (-)Ensembl
RefSeq Acc Id: ENSMUST00000120918   ⟹   ENSMUSP00000113034
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,577,849 - 121,642,096 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125075   ⟹   ENSMUSP00000115284
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,584,087 - 121,641,526 (-)Ensembl
RefSeq Acc Id: ENSMUST00000213757   ⟹   ENSMUSP00000151031
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,578,049 - 121,641,498 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214592   ⟹   ENSMUSP00000150807
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,584,090 - 121,641,571 (-)Ensembl
RefSeq Acc Id: NM_001357346   ⟹   NP_001344275
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,406,915 - 121,471,187 (-)NCBI
GRCm389121,577,849 - 121,642,121 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001382835   ⟹   NP_001369764
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,406,915 - 121,416,027 (-)NCBI
GRCm389121,577,849 - 121,586,961 (-)NCBI
RefSeq Acc Id: NM_026915   ⟹   NP_081191
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,406,915 - 121,470,660 (-)NCBI
GRCm389121,577,849 - 121,641,594 (-)NCBI
MGSCv379121,486,961 - 121,550,684 (-)RGD
Celera9122,047,977 - 122,114,890 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512248   ⟹   XP_006512311
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,406,907 - 121,421,077 (-)NCBI
GRCm389121,577,841 - 121,592,011 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_081191   ⟸   NM_026915
- Peptide Label: precursor
- UniProtKB: Q9D925 (UniProtKB/Swiss-Prot),   Q78ID0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006512311   ⟸   XM_006512248
- Peptide Label: isoform X1
- UniProtKB: Q9D925 (UniProtKB/Swiss-Prot),   Q78ID0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001344275   ⟸   NM_001357346
- Peptide Label: precursor
RefSeq Acc Id: NP_001369764   ⟸   NM_001382835
- Peptide Label: precursor
RefSeq Acc Id: ENSMUSP00000115284   ⟸   ENSMUST00000125075
RefSeq Acc Id: ENSMUSP00000113034   ⟸   ENSMUST00000120918
RefSeq Acc Id: ENSMUSP00000151031   ⟸   ENSMUST00000213757
RefSeq Acc Id: ENSMUSP00000076887   ⟸   ENSMUST00000077706
RefSeq Acc Id: ENSMUSP00000150807   ⟸   ENSMUST00000214592

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916282 AgrOrtholog
Ensembl Genes ENSMUSG00000032530 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000076887 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000113034 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000115284 UniProtKB/TrEMBL
  ENSMUSP00000150807 UniProtKB/TrEMBL
  ENSMUSP00000151031 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000077706 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000120918 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000125075 UniProtKB/TrEMBL
  ENSMUST00000213757 UniProtKB/TrEMBL
  ENSMUST00000214592 UniProtKB/TrEMBL
InterPro Glyco_hydro_22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_22_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_22_lys UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lysozyme-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LYZL4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69032 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1916282 ENTREZGENE
NCBI Gene 69032 ENTREZGENE
PANTHER PTHR11407:SF21 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Lys UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lyzl4 PhenoGen
PRINTS LYSOZYME UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LYZLACT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLYCOSYL_HYDROL_F22_1 UniProtKB/TrEMBL
  GLYCOSYL_HYDROL_F22_2 UniProtKB/TrEMBL
  LACTALBUMIN_LYSOZYME_1 UniProtKB/Swiss-Prot
  LACTALBUMIN_LYSOZYME_2 UniProtKB/Swiss-Prot
SMART LYZ1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53955 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.33351 ENTREZGENE
UniProt A0A1L1SUM6_MOUSE UniProtKB/TrEMBL
  A0A1L1SV59_MOUSE UniProtKB/TrEMBL
  D3YUC1_MOUSE UniProtKB/TrEMBL
  LYZL4_MOUSE UniProtKB/Swiss-Prot
  Q78ID0 ENTREZGENE, UniProtKB/TrEMBL
  Q9D925 ENTREZGENE