Chat (choline acetyltransferase) - Rat Genome Database
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Gene: Chat (choline acetyltransferase) Mus musculus
Analyze
Symbol: Chat
Name: choline acetyltransferase
RGD ID: 1549990
MGI Page MGI
Description: Exhibits choline O-acetyltransferase activity. Involved in several processes, including adult walking behavior; establishment of synaptic specificity at neuromuscular junction; and rhythmic excitation. Localizes to axon; cytoplasm; and neuronal cell body. Is expressed in several structures, including alimentary system; cranium; heart; nervous system; and retina. Used to study congenital myasthenic syndrome 6. Human ortholog(s) of this gene implicated in Alzheimer's disease and congenital myasthenic syndrome 6. Orthologous to human CHAT (choline O-acetyltransferase); PARTICIPATES IN acetylcholine metabolic pathway; acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (20R)-protopanaxadiol; 5-azacytidine; [6]-Shogaol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B230380D24Rik; CHOACTase; choline acetylase; choline O-acetyltransferase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391432,130,160 - 32,187,866 (-)NCBIGRCm39mm39
GRCm381432,408,203 - 32,465,909 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1432,408,203 - 32,465,989 (-)EnsemblGRCm38mm10GRCm38
MGSCv371433,221,389 - 33,279,095 (-)NCBIGRCm37mm9NCBIm37
MGSCv361431,237,212 - 31,294,918 (-)NCBImm8
Celera1428,665,793 - 28,723,609 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
(+)-pilocarpine  (ISO)
(20R)-protopanaxadiol  (EXP)
(R)-lipoic acid  (ISO)
(S)-nicotine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
5-azacytidine  (EXP)
[6]-Shogaol  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
alpha-D-galactose  (EXP)
aluminium atom  (EXP)
aluminium(0)  (EXP)
amiodarone  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bifenthrin  (ISO)
bisphenol A  (ISO)
bucladesine  (EXP,ISO)
butanal  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
catalpol  (EXP)
chlorpyrifos  (EXP,ISO)
cis-caffeic acid  (EXP)
curcumin  (ISO)
cyanamide  (ISO)
cyfluthrin  (ISO)
cypermethrin  (ISO)
cytarabine  (ISO)
daidzein  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dichlorvos  (ISO)
dimethylarsinic acid  (EXP)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
galactose  (EXP)
ginsenoside Rd  (EXP)
ginsenoside Re  (EXP)
herbicide  (EXP)
hydrogen peroxide  (EXP)
inositol  (ISO)
L-ascorbic acid  (ISO)
lipoic acid  (ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP)
meloxicam  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
methamphetamine  (ISO)
methyllycaconitine  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-ethylmaleimide  (EXP)
N-nitrosodiethylamine  (ISO)
nicotine  (ISO)
nitroprusside  (EXP)
notoginsenoside R1  (EXP)
oleamide  (ISO)
paraquat  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
physostigmine  (ISO)
progesterone  (EXP)
Pyridostigmine bromide  (ISO)
quercetin  (ISO)
quinolinic acid  (ISO)
resveratrol  (ISO)
sarin  (ISO)
scopolamine  (EXP,ISO)
serotonin  (EXP)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
streptozocin  (ISO)
tacrine  (EXP)
taurine  (ISO)
terbutaline  (ISO)
thioacetamide  (ISO)
trans-caffeic acid  (EXP)
tributylstannane  (EXP)
triclosan  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IDA)
cytoplasm  (IBA,IDA)
mitochondrion  (HDA)
neuron projection  (IBA,IDA,ISO)
neuronal cell body  (IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal amacrine cell morphology  (IAGP)
abnormal axon morphology  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal dendrite morphology  (IAGP)
abnormal gait  (IAGP)
abnormal gastrocnemius morphology  (IAGP)
abnormal habituation to a new environment  (IAGP)
abnormal heartbeat  (IAGP)
abnormal inhibitory postsynaptic currents  (IAGP)
abnormal innervation  (IAGP)
abnormal innervation pattern to muscle  (IAGP)
abnormal miniature endplate potential  (IAGP)
abnormal motor neuron innervation pattern  (IAGP)
abnormal muscle morphology  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal neuromuscular synapse morphology  (IAGP)
abnormal phrenic nerve morphology  (IAGP)
abnormal PNS synaptic transmission  (IAGP)
abnormal respiration  (IAGP)
abnormal retinal inner plexiform layer morphology  (IAGP)
abnormal Schwann cell morphology  (IAGP)
abnormal skeletal muscle morphology  (IAGP)
abnormal soleus morphology  (IAGP)
abnormal synaptic acetylcholine release  (IAGP)
abnormal tail morphology  (IAGP)
abnormal whole-body plethysmography  (IAGP)
apnea  (IAGP)
carpoptosis  (IAGP)
corneal opacity  (IAGP)
cyanosis  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased fetal size  (IAGP)
decreased heart rate  (IAGP)
decreased pulmonary respiratory rate  (IAGP)
decreased vertical activity  (IAGP)
diaphragmatic hernia  (IAGP)
hyperactivity  (IAGP)
hypertension  (IAGP)
hypoactivity  (IAGP)
hypotonia  (IAGP)
increased acetylcholine level  (IAGP)
increased airway responsiveness  (IAGP)
increased brain choline acetyltransferase activity  (IAGP)
increased circulating insulin level  (IAGP)
increased heart rate variability  (IAGP)
increased motor neuron number  (IAGP)
increased response of heart to induced stress  (IAGP)
increased vertical activity  (IAGP)
kyphosis  (IAGP)
motor neuron degeneration  (IAGP)
muscle weakness  (IAGP)
muscular atrophy  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
prolonged QT interval  (IAGP)
rectal prolapse  (IAGP)
skeletal muscle atrophy  (IAGP)
skeletal muscle endomysial fibrosis  (IAGP)
skeletal muscle fiber atrophy  (IAGP)
skeletal muscle fibrosis  (IAGP)
tail dragging  (IAGP)
thin diaphragm muscle  (IAGP)
tremors  (IAGP)
ventricular premature beat  (IAGP)
ventricular tachycardia  (IAGP)
weakness  (IAGP)
References

Additional References at PubMed
PMID:1400357   PMID:2160042   PMID:2292721   PMID:7499852   PMID:7903221   PMID:7979162   PMID:8294908   PMID:8565076   PMID:8657307   PMID:8660977   PMID:8756299   PMID:8793115  
PMID:8858346   PMID:8922421   PMID:8955272   PMID:9102308   PMID:9223334   PMID:9374403   PMID:9398437   PMID:9417917   PMID:9427309   PMID:9603187   PMID:9636069   PMID:9853118  
PMID:9865699   PMID:10336693   PMID:10349636   PMID:10454512   PMID:10482234   PMID:10482239   PMID:10864958   PMID:10934256   PMID:11042159   PMID:11076861   PMID:11156601   PMID:11217851  
PMID:11466434   PMID:11581159   PMID:11588182   PMID:11749040   PMID:11807038   PMID:11846786   PMID:11875658   PMID:11900467   PMID:12012374   PMID:12019323   PMID:12115678   PMID:12139922  
PMID:12441053   PMID:12466206   PMID:12467588   PMID:12477932   PMID:12533614   PMID:12619134   PMID:12642493   PMID:12682014   PMID:12855770   PMID:12879071   PMID:12885554   PMID:12888222  
PMID:14513037   PMID:14598259   PMID:14662765   PMID:14681479   PMID:14980377   PMID:15173594   PMID:15201317   PMID:15217369   PMID:15233745   PMID:15240886   PMID:15255940   PMID:15353224  
PMID:15497153   PMID:15666354   PMID:15820692   PMID:15837129   PMID:15944126   PMID:15972963   PMID:15978004   PMID:16026391   PMID:16043708   PMID:16141072   PMID:16141073   PMID:16221724  
PMID:16221843   PMID:16236524   PMID:16272887   PMID:16467531   PMID:16525473   PMID:16537079   PMID:16602821   PMID:16638018   PMID:16691566   PMID:16738228   PMID:16815098   PMID:16846505  
PMID:16968817   PMID:17017126   PMID:17084985   PMID:17092954   PMID:17192424   PMID:17320829   PMID:17415677   PMID:17460091   PMID:17480014   PMID:17626062   PMID:17709753   PMID:17729288  
PMID:17990271   PMID:18084773   PMID:18086710   PMID:18094249   PMID:18199763   PMID:18313668   PMID:18367596   PMID:18430798   PMID:18454144   PMID:18460603   PMID:18492800   PMID:18614015  
PMID:18665422   PMID:18675571   PMID:18700968   PMID:18719084   PMID:18787067   PMID:18926818   PMID:19029045   PMID:19088125   PMID:19088126   PMID:19116659   PMID:19162134   PMID:19236857  
PMID:19339595   PMID:19398581   PMID:19421194   PMID:19542360   PMID:19549840   PMID:19605412   PMID:19635813   PMID:19641107   PMID:19662096   PMID:19717447   PMID:19726636   PMID:19837136  
PMID:19855026   PMID:19855129   PMID:19906978   PMID:19924248   PMID:19945391   PMID:20005822   PMID:20019802   PMID:20023653   PMID:20107080   PMID:20123977   PMID:20176735   PMID:20181579  
PMID:20181580   PMID:20220021   PMID:20231872   PMID:20484637   PMID:20495559   PMID:20498043   PMID:20519544   PMID:20549744   PMID:20631175   PMID:20818386   PMID:20826655   PMID:20921407  
PMID:20949055   PMID:21048141   PMID:21048147   PMID:21205893   PMID:21228161   PMID:21270893   PMID:21284986   PMID:21305030   PMID:21423695   PMID:21445349   PMID:21451052   PMID:21508241  
PMID:21533046   PMID:21544206   PMID:21593306   PMID:21606356   PMID:21651972   PMID:21677750   PMID:21690261   PMID:21702872   PMID:21790808   PMID:21813676   PMID:21835343   PMID:21865321  
PMID:21873635   PMID:21903076   PMID:21921156   PMID:21925604   PMID:21935943   PMID:21943603   PMID:21962519   PMID:21989918   PMID:22087075   PMID:22090484   PMID:22098391   PMID:22226696  
PMID:22267162   PMID:22300281   PMID:22315402   PMID:22378886   PMID:22407321   PMID:22423106   PMID:22446880   PMID:22460939   PMID:22641085   PMID:22674265   PMID:22683430   PMID:22723710  
PMID:22723712   PMID:22820053   PMID:22828515   PMID:22836272   PMID:22842903   PMID:22875923   PMID:22884324   PMID:22895728   PMID:23041116   PMID:23045697   PMID:23103965   PMID:23132022  
PMID:23152916   PMID:23165118   PMID:23197720   PMID:23227180   PMID:23240572   PMID:23283320   PMID:23312282   PMID:23319656   PMID:23352170   PMID:23374353   PMID:23390312   PMID:23408898  
PMID:23420014   PMID:23468099   PMID:23474986   PMID:23525439   PMID:23555309   PMID:23591430   PMID:23648511   PMID:23649862   PMID:23652001   PMID:23749724   PMID:23777652   PMID:23785154  
PMID:23790753   PMID:23806960   PMID:23810416   PMID:23817127   PMID:23821205   PMID:23831966   PMID:23866336   PMID:24018063   PMID:24021673   PMID:24027290   PMID:24073291   PMID:24082127  
PMID:24086156   PMID:24155009   PMID:24157949   PMID:24179230   PMID:24190932   PMID:24227714   PMID:24327562   PMID:24333658   PMID:24344165   PMID:24351932   PMID:24395778   PMID:24428937  
PMID:24453327   PMID:24462097   PMID:24486622   PMID:24558155   PMID:24559672   PMID:24672011   PMID:24712519   PMID:24763339   PMID:24776795   PMID:24799694   PMID:24844149   PMID:24880216  
PMID:24894464   PMID:24904300   PMID:24908101   PMID:24927931   PMID:24952961   PMID:25057212   PMID:25071457   PMID:25100604   PMID:25113559   PMID:25126785   PMID:25155960   PMID:25197052  
PMID:25228773   PMID:25261598   PMID:25338097   PMID:25456121   PMID:25467445   PMID:25476605   PMID:25482555   PMID:25503925   PMID:25534911   PMID:25543457   PMID:25556796   PMID:25589590  
PMID:25589777   PMID:25641263   PMID:25661788   PMID:25682262   PMID:25723967   PMID:25739505   PMID:25741722   PMID:25762373   PMID:25805134   PMID:25826454   PMID:25892222   PMID:25904846  
PMID:25918499   PMID:26042202   PMID:26044557   PMID:26079645   PMID:26082752   PMID:26109653   PMID:26140686   PMID:26151909   PMID:26166575   PMID:26170298   PMID:26186188   PMID:26206889  
PMID:26226617   PMID:26287463   PMID:26317475   PMID:26335645   PMID:26356988   PMID:26389685   PMID:26395878   PMID:26400950   PMID:26442852   PMID:26446210   PMID:26449264   PMID:26457552  
PMID:26503322   PMID:26542008   PMID:26558771   PMID:26623516   PMID:26633812   PMID:26647347   PMID:26680198   PMID:26711119   PMID:26718003   PMID:26718312   PMID:26727548   PMID:26758839  
PMID:26793064   PMID:26803167   PMID:26804990   PMID:26842965   PMID:26858598   PMID:26949938   PMID:26951610   PMID:27030771   PMID:27098031   PMID:27100198   PMID:27103432   PMID:27112419  
PMID:27112494   PMID:27122033   PMID:27161525   PMID:27161528   PMID:27170656   PMID:27210555   PMID:27221609   PMID:27225763   PMID:27238865   PMID:27243816   PMID:27277805   PMID:27279213  
PMID:27312991   PMID:27378584   PMID:27383271   PMID:27418600   PMID:27454033   PMID:27462817   PMID:27482535   PMID:27514477   PMID:27568555   PMID:27568569   PMID:27581457   PMID:27604129  
PMID:27617738   PMID:27642784   PMID:27647894   PMID:27650319   PMID:27658674   PMID:27773584   PMID:27810937   PMID:27819291   PMID:27824036   PMID:27886263   PMID:27889925   PMID:27911814  
PMID:27929372   PMID:27930290   PMID:27991864   PMID:28002412   PMID:28017471   PMID:28086095   PMID:28091925   PMID:28093257   PMID:28128321   PMID:28159985   PMID:28167615   PMID:28178238  
PMID:28190640   PMID:28192394   PMID:28289129   PMID:28297715   PMID:28347488   PMID:28377698   PMID:28384713   PMID:28387937   PMID:28392070   PMID:28416596   PMID:28420791   PMID:28433741  
PMID:28441398   PMID:28450636   PMID:28497110   PMID:28504671   PMID:28530661   PMID:28551284   PMID:28591834   PMID:28625486   PMID:28648825   PMID:28656980   PMID:28671548   PMID:28684471  
PMID:28694260   PMID:28698373   PMID:28714952   PMID:28760865   PMID:28771790   PMID:28775269   PMID:28779160   PMID:28781167   PMID:28791701   PMID:28811488   PMID:28813670   PMID:28815501  
PMID:28869582   PMID:28869965   PMID:28869974   PMID:28904095   PMID:28916788   PMID:28935940   PMID:28942925   PMID:28973166   PMID:29030431   PMID:29031500   PMID:29045834   PMID:29107522  
PMID:29113945   PMID:29137925   PMID:29141212   PMID:29162816   PMID:29192291   PMID:29203898   PMID:29216450   PMID:29259118   PMID:29262336   PMID:29268098   PMID:29281826   PMID:29323161  
PMID:29337309   PMID:29342142   PMID:29343636   PMID:29358049   PMID:29371319   PMID:29437952   PMID:29439167   PMID:29487212   PMID:29487284   PMID:29509880   PMID:29526593   PMID:29570391  
PMID:29578407   PMID:29606419   PMID:29606582   PMID:29611808   PMID:29615610   PMID:29659809   PMID:29714166   PMID:29758086   PMID:29761601   PMID:29785025   PMID:29791835   PMID:29878134  
PMID:29915194   PMID:29967281   PMID:29972353   PMID:30001398   PMID:30030438   PMID:30058223   PMID:30061574   PMID:30078709   PMID:30087345   PMID:30089022   PMID:30113308   PMID:30117805  
PMID:30122379   PMID:30127719   PMID:30194386   PMID:30206360   PMID:30208054   PMID:30208314   PMID:30225352   PMID:30275816   PMID:30295421   PMID:30373769   PMID:30392798   PMID:30449655  
PMID:30485816   PMID:30487221   PMID:30509993   PMID:30540946   PMID:30541618   PMID:30556914   PMID:30578339   PMID:30593496   PMID:30594427   PMID:30658860   PMID:30671536   PMID:30714905  
PMID:30726725   PMID:30733420   PMID:30787434   PMID:30804092   PMID:30819512   PMID:30824771   PMID:30833511   PMID:30862827   PMID:30870413   PMID:30870432   PMID:30920369   PMID:30943416  
PMID:30948552   PMID:31002540   PMID:31024522   PMID:31028115   PMID:31076274   PMID:31078140   PMID:31087513   PMID:31119189   PMID:31160566   PMID:31178114   PMID:31185023   PMID:31200100  
PMID:31242414   PMID:31285615   PMID:31324539   PMID:31340139   PMID:31366590   PMID:31396962   PMID:31403401   PMID:31427287   PMID:31444227   PMID:31470043   PMID:31488566   PMID:31541001  
PMID:31562178   PMID:31578231   PMID:31609468   PMID:31611772   PMID:31619789   PMID:31625606   PMID:31665630   PMID:31693896   PMID:31719165   PMID:31781038   PMID:31782602   PMID:31812516  
PMID:31851921   PMID:31875546   PMID:31944180   PMID:31975627   PMID:31975688   PMID:31995757   PMID:32027647   PMID:32027825   PMID:32032507   PMID:32047156   PMID:32096758   PMID:32096760  
PMID:32111698   PMID:32220666   PMID:32240599   PMID:32294408   PMID:32353253   PMID:32420873   PMID:32450295   PMID:32521265   PMID:32581716   PMID:32613945   PMID:32641826   PMID:32690615  
PMID:32747435   PMID:32750380   PMID:32817066   PMID:32945260   PMID:33082323   PMID:33164988   PMID:33300873  


Genomics

Comparative Map Data
Chat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391432,130,160 - 32,187,866 (-)NCBIGRCm39mm39
GRCm381432,408,203 - 32,465,909 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1432,408,203 - 32,465,989 (-)EnsemblGRCm38mm10GRCm38
MGSCv371433,221,389 - 33,279,095 (-)NCBIGRCm37mm9NCBIm37
MGSCv361431,237,212 - 31,294,918 (-)NCBImm8
Celera1428,665,793 - 28,723,609 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.4NCBI
CHAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1049,609,095 - 49,667,942 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1049,609,095 - 49,665,104 (+)EnsemblGRCh38hg38GRCh38
GRCh381049,609,095 - 49,667,942 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371050,817,141 - 50,875,988 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh371050,817,141 - 50,873,150 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361050,487,147 - 50,543,156 (+)NCBINCBI36hg18NCBI36
Celera1044,403,227 - 44,459,207 (+)NCBI
Cytogenetic Map10q11.23NCBI
HuRef1045,081,909 - 45,138,016 (+)NCBIHuRef
CHM1_11051,099,225 - 51,155,226 (+)NCBICHM1_1
Chat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2167,657,362 - 7,717,093 (-)NCBI
Rnor_6.0 Ensembl168,577,840 - 8,686,131 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0168,576,858 - 8,686,131 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01610,603,449 - 10,652,313 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0168,493,024 - 8,526,303 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,913,026 - 7,965,985 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1167,913,023 - 7,968,456 (-)NCBI
Celera167,483,676 - 7,543,221 (+)NCBICelera
Cytogenetic Map16p16NCBI
Chat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955556650,279 - 693,276 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955556650,290 - 695,135 (-)NCBIChiLan1.0ChiLan1.0
CHAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v01044,574,925 - 44,629,618 (-)NCBIMhudiblu_PPA_v0panPan3
CHAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl281,482,202 - 1,528,776 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1281,480,364 - 1,528,858 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Chat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936728653,654 - 702,433 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1490,117,464 - 90,167,611 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11490,117,464 - 90,167,611 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21498,025,088 - 98,075,314 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q25-q27NCBI
CHAT
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1942,159,367 - 42,216,137 (-)NCBI
ChlSab1.1 Ensembl942,162,601 - 42,214,705 (-)Ensembl
Chat
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624928357,812 - 401,668 (-)NCBI

Position Markers
D14Mit52  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381432,438,659 - 32,438,808UniSTSGRCm38
MGSCv371433,251,845 - 33,251,994UniSTSGRCm37
Celera1428,696,270 - 28,696,419UniSTS
Cytogenetic Map14BUniSTS
cM Map1411.5UniSTS
Whitehead Genetic1418.6UniSTS
Whitehead_YAC14 UniSTS
Chat  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371433,272,775 - 33,272,985UniSTSGRCm37
Celera1428,717,293 - 28,717,503UniSTS
Cytogenetic Map14BUniSTS
cM Map1410.5UniSTS
cM Map1410.5UniSTS
Chat  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381432,459,589 - 32,459,799UniSTSGRCm38
MGSCv371433,272,775 - 33,272,985UniSTSGRCm37
Celera1428,717,293 - 28,717,503UniSTS
Cytogenetic Map14BUniSTS
cM Map1410.5UniSTS
Chat  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14BUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301991Wta3_mweight adult 3 (mouse)Not determined14383740537837582Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined509340539093528Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)14870000046500000Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)14870000047000000Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141249091446491050Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined1254601848527625Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141543865949438808Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141910564753105769Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142101238271648361Mouse
14746973Manh76_mmandible shape 76 (mouse)142256526056565260Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492582457942312Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142820000060900000Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142975953763759676Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143009779364097924Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143009779364097924Mouse
27226775Tibl7_mtibia length 7, 5 week (mouse)143060000048600000Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143060000052700000Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143060000087700000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:282
Count of miRNA genes:210
Interacting mature miRNAs:235
Transcripts:ENSMUST00000070125
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC167565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC119322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC120589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L16517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000070125   ⟹   ENSMUSP00000070865
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1432,408,203 - 32,465,957 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226351   ⟹   ENSMUSP00000153857
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1432,454,706 - 32,465,957 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226365   ⟹   ENSMUSP00000153721
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1432,446,919 - 32,465,989 (-)Ensembl
RefSeq Acc Id: ENSMUST00000227579   ⟹   ENSMUSP00000153738
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1432,446,919 - 32,460,940 (-)Ensembl
RefSeq Acc Id: ENSMUST00000227675
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1432,450,868 - 32,460,911 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228256   ⟹   ENSMUSP00000154480
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1432,454,706 - 32,462,042 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228420   ⟹   ENSMUSP00000153964
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1432,454,706 - 32,462,042 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228511   ⟹   ENSMUSP00000153837
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1432,454,706 - 32,465,957 (-)Ensembl
RefSeq Acc Id: NM_009891   ⟹   NP_034021
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,130,160 - 32,187,866 (-)NCBI
GRCm381432,408,203 - 32,465,909 (-)ENTREZGENE
MGSCv371433,221,389 - 33,279,095 (-)RGD
Celera1428,665,793 - 28,723,609 (-)RGD
cM Map14 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034021   ⟸   NM_009891
- UniProtKB: Q8BQV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000070865   ⟸   ENSMUST00000070125
RefSeq Acc Id: ENSMUSP00000154480   ⟸   ENSMUST00000228256
RefSeq Acc Id: ENSMUSP00000153738   ⟸   ENSMUST00000227579
RefSeq Acc Id: ENSMUSP00000153857   ⟸   ENSMUST00000226351
RefSeq Acc Id: ENSMUSP00000153721   ⟸   ENSMUST00000226365
RefSeq Acc Id: ENSMUSP00000153837   ⟸   ENSMUST00000228511
RefSeq Acc Id: ENSMUSP00000153964   ⟸   ENSMUST00000228420
Protein Domains
Carn_acyltransf

Promoters
RGD ID:8681868
Promoter ID:EPDNEW_M18965
Type:multiple initiation site
Name:Chat_1
Description:Mus musculus choline acetyltransferase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381432,460,907 - 32,460,967EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88392 AgrOrtholog
Ensembl Genes ENSMUSG00000021919 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000070865 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000153721 UniProtKB/TrEMBL
  ENSMUSP00000153738 UniProtKB/TrEMBL
  ENSMUSP00000153837 UniProtKB/TrEMBL
  ENSMUSP00000153857 UniProtKB/TrEMBL
  ENSMUSP00000153964 UniProtKB/TrEMBL
  ENSMUSP00000154480 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000070125 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000226351 UniProtKB/TrEMBL
  ENSMUST00000226365 UniProtKB/TrEMBL
  ENSMUST00000227579 UniProtKB/TrEMBL
  ENSMUST00000228256 UniProtKB/TrEMBL
  ENSMUST00000228420 UniProtKB/TrEMBL
  ENSMUST00000228511 UniProtKB/TrEMBL
Gene3D-CATH 3.30.559.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.559.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Carn_acyl_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cho/carn_acyl_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cho/carn_acyl_trans_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cho/carn_acyl_trans_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12647 UniProtKB/TrEMBL
MGD MGI:88392 ENTREZGENE
NCBI Gene 12647 ENTREZGENE
PANTHER PTHR22589 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Carn_acyltransf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB CHAT RGD
PhenoGen Chat PhenoGen
PROSITE ACYLTRANSF_C_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACYLTRANSF_C_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BPD4_MOUSE UniProtKB/TrEMBL
  A0A2I3BPY2_MOUSE UniProtKB/TrEMBL
  CLAT_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8BQN4_MOUSE UniProtKB/TrEMBL
  Q8BQV2 ENTREZGENE, UniProtKB/TrEMBL