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Gene: Vegfb (vascular endothelial growth factor B) Mus musculus
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Symbol: Vegfb
Name: vascular endothelial growth factor B
Description: Exhibits protein heterodimerization activity and protein homodimerization activity. Involved in cardiac muscle contraction; coronary vasculature development; and protein O-linked glycosylation. Localizes to the extracellular region. Human ortholog(s) of this gene implicated in myocardial infarction and pulmonary hypertension. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and trunk. Orthologous to human VEGFB (vascular endothelial growth factor B); PARTICIPATES IN vascular endothelial growth factor signaling pathway; ceramide signaling pathway; mTOR signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: VEGF-B; VEGF-related factor; Vrf
Orthologs:
Homo sapiens (human) : VEGFB (vascular endothelial growth factor B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vegfb (vascular endothelial growth factor B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vegfb (vascular endothelial growth factor B)
Canis lupus familiaris (dog) : VEGFB (vascular endothelial growth factor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vegfb (vascular endothelial growth factor B)
Sus scrofa (pig) : VEGFB (vascular endothelial growth factor B)
Chlorocebus sabaeus (green monkey) : VEGFB (vascular endothelial growth factor B)
Heterocephalus glaber (naked mole-rat) : Vegfb (vascular endothelial growth factor B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl196,982,473 - 6,987,651 (-)Ensembl
GRCm38196,982,472 - 6,987,651 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37197,056,962 - 7,062,141 (-)NCBIGRCm37mm9NCBIm37
MGSCv36197,049,516 - 7,054,647 (-)NCBImm8
Celera196,759,390 - 6,764,564 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Vegfb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1622354
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.