(+)-catechin multiple interactions ISO RGD:1606040 6480464 Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of ATM mRNA] CTD PMID:21882252 (1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ATM mRNA CTD PMID:36331819 (1S)-bornane-2,3-dione increases phosphorylation ISO RGD:1606040 6480464 camphorquinone results in increased phosphorylation of ATM protein CTD PMID:26658076 (S)-naringenin multiple interactions ISO RGD:1606040 6480464 [naringenin co-treated with bisphenol A] results in increased expression of ATM mRNA, [naringenin metabolite co-treated with bisphenol A] results in increased expression of ATM mRNA CTD PMID:36235125 (S)-nicotine multiple interactions ISO RGD:1606040 6480464 Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of ATM protein modified form] CTD PMID:23907605 1,2-dichloroethane decreases expression EXP 6480464 ethylene dichloride results in decreased expression of ATM mRNA CTD PMID:28960355 1,2-dimethylhydrazine affects expression EXP 6480464 1, 2-Dimethylhydrazine affects the expression of ATM mRNA CTD PMID:22206623 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of ATM mRNA CTD PMID:22467019 17beta-estradiol decreases expression ISO RGD:1606040 6480464 Estradiol results in decreased expression of ATM mRNA CTD PMID:24481588 17beta-estradiol increases expression ISO RGD:1606040 6480464 Estradiol results in increased expression of ATM protein modified form CTD PMID:25933419 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:1606040 6480464 [ATM mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein]] which results in increased expression of ERG mRNA, ATM mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein] CTD PMID:23272087 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases phosphorylation ISO RGD:1606040 6480464 Metribolone results in increased phosphorylation of ATM protein CTD PMID:23272087 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:1606040 6480464 2 more ... CTD PMID:26988655 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ATM mRNA CTD PMID:16922920 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1593265 6480464 Tetrachlorodibenzodioxin results in decreased expression of ATM mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1593265 6480464 Tetrachlorodibenzodioxin results in increased expression of ATM mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ATM mRNA CTD PMID:21570461 2-amino-2-deoxy-D-galactopyranose increases expression ISO RGD:1593265 6480464 Galactosamine results in increased expression of ATM protein CTD PMID:24565947 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO RGD:1593265 6480464 glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of ATM protein] CTD PMID:24565947 2-methylcholine affects expression ISO RGD:1606040 6480464 beta-methylcholine affects the expression of ATM mRNA CTD PMID:21179406 3-aminobenzamide multiple interactions ISO RGD:1606040 6480464 3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein] CTD PMID:22226932 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:1606040 6480464 [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of ATM mRNA, Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of ATM mRNA] CTD PMID:21882252 4-amino-1,8-naphthalimide multiple interactions EXP 6480464 ATM protein affects the reaction [4-amino-1 more ... CTD PMID:16556909 4-amino-1,8-naphthalimide increases phosphorylation EXP 6480464 4-amino-1, 8-naphthalimide results in increased phosphorylation of ATM protein CTD PMID:16556909 4-amino-1,8-naphthalimide affects response to substance EXP 6480464 ATM protein affects the susceptibility to 4-amino-1, 8-naphthalimide CTD PMID:16556909 4-hydroxynon-2-enal increases expression EXP 6480464 4-hydroxy-2-nonenal results in increased expression of ATM mRNA CTD PMID:19191707 5-(hydroxymethyl)cytosine decreases methylation ISO RGD:1606040 6480464 5-hydroxymethylcytosine results in decreased methylation of ATM gene CTD PMID:30990028 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1606040 6480464 ATM protein affects the reaction [Decitabine results in increased expression of H2AX protein] CTD PMID:17991895 5-aza-2'-deoxycytidine decreases methylation ISO RGD:1606040 6480464 Decitabine results in decreased methylation of ATM gene CTD PMID:30990028 5-aza-2'-deoxycytidine affects methylation ISO RGD:1606040 6480464 Decitabine affects the methylation of ATM promoter CTD PMID:17488656 5-aza-2'-deoxycytidine affects localization ISO RGD:1606040 6480464 Decitabine affects the localization of ATM protein modified form CTD PMID:17991895 5-aza-2'-deoxycytidine affects response to substance ISO RGD:1606040 6480464 ATM protein affects the susceptibility to Decitabine CTD PMID:17991895 5-chloro-7-iodoquinolin-8-ol increases phosphorylation ISO RGD:1606040 6480464 Clioquinol results in increased phosphorylation of ATM protein CTD PMID:22627294 5-fluorouracil decreases response to substance ISO RGD:1606040 6480464 ATM protein results in decreased susceptibility to Fluorouracil CTD PMID:35608750 7,12-dimethyltetraphene multiple interactions ISO RGD:1593265 6480464 9 more ... CTD PMID:23969067 7,12-dimethyltetraphene multiple interactions EXP 6480464 9 more ... CTD PMID:25448685 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:25448685 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:25448685 7,12-dimethyltetraphene increases expression ISO RGD:1593265 6480464 9 more ... CTD PMID:23969067 acetylsalicylic acid increases expression ISO RGD:1606040 6480464 Aspirin results in increased expression of ATM mRNA CTD PMID:20457246 acrolein multiple interactions ISO RGD:1606040 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ATM mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ATM mRNA CTD PMID:32699268 acrolein increases phosphorylation ISO RGD:1606040 6480464 Acrolein results in increased phosphorylation of ATM protein CTD PMID:34958888 acrylamide multiple interactions ISO RGD:1606040 6480464 [[Caffeine results in decreased activity of ATR protein] co-treated with [Caffeine results in decreased activity of ATM protein]] results in decreased susceptibility to Acrylamide CTD PMID:20734998 actinomycin D multiple interactions ISO RGD:1606040 6480464 Dactinomycin results in decreased expression of and results in increased phosphorylation of ATM protein CTD PMID:31226288 Aflatoxin G1 increases expression ISO RGD:1606040 6480464 aflatoxin G1 results in increased expression of ATM protein modified form CTD PMID:23907605 Aflatoxin G1 multiple interactions ISO RGD:1606040 6480464 Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of ATM protein modified form], Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of ATM protein modified form] CTD PMID:23907605 Aflatoxin G1 increases activity ISO RGD:1606040 6480464 aflatoxin G1 results in increased activity of ATM protein CTD PMID:23907605 aflatoxin M1 decreases expression ISO RGD:1606040 6480464 Aflatoxin M1 results in decreased expression of ATM mRNA CTD PMID:30928695 all-trans-retinoic acid increases expression ISO RGD:1606040 6480464 Tretinoin results in increased expression of ATM mRNA CTD PMID:23724009 alpha-pinene multiple interactions ISO RGD:1606040 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ATM mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ATM mRNA CTD PMID:32699268 amphetamine decreases expression ISO RGD:1593265 6480464 Amphetamine results in decreased expression of ATM mRNA CTD PMID:30779732 amphibole asbestos decreases expression ISO RGD:1606040 6480464 Asbestos, Amphibole results in decreased expression of ATM protein CTD PMID:20855422 anthocyanin increases phosphorylation ISO RGD:1606040 6480464 Anthocyanins results in increased phosphorylation of ATM protein CTD PMID:27444805 antimycin A decreases expression ISO RGD:1606040 6480464 Antimycin A results in decreased expression of ATM mRNA CTD PMID:33512557 aphidicolin multiple interactions EXP 6480464 [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein], [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 aristolochic acids increases expression ISO RGD:1606040 6480464 Aristolochic Acids results in increased expression of ATM protein modified form CTD PMID:24792323 aristolochic acids multiple interactions ISO RGD:1606040 6480464 Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of ATM protein modified form] CTD PMID:24792323 arsane affects methylation ISO RGD:1606040 6480464 Arsenic affects the methylation of ATM gene CTD PMID:25304211 arsane multiple interactions ISO RGD:1606040 6480464 [UNG protein affects the susceptibility to Arsenic] which affects the phosphorylation of ATM protein, APOBEC3B protein affects the reaction [[UNG protein affects the susceptibility to Arsenic] which affects the phosphorylation of ATM protein] CTD PMID:34998823 arsenic atom affects methylation ISO RGD:1606040 6480464 Arsenic affects the methylation of ATM gene CTD PMID:25304211 arsenic atom multiple interactions ISO RGD:1606040 6480464 [UNG protein affects the susceptibility to Arsenic] which affects the phosphorylation of ATM protein, APOBEC3B protein affects the reaction [[UNG protein affects the susceptibility to Arsenic] which affects the phosphorylation of ATM protein] CTD PMID:34998823 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of ATM mRNA CTD PMID:33053406 arsenite(3-) multiple interactions ISO RGD:1606040 6480464 arsenite inhibits the reaction [G3BP1 protein binds to ATM mRNA] CTD PMID:32406909 arsenous acid decreases expression ISO RGD:1606040 6480464 Arsenic Trioxide results in decreased expression of ATM mRNA, Arsenic Trioxide results in decreased expression of ATM protein modified form CTD PMID:19763917 more ... arsenous acid decreases phosphorylation ISO RGD:1606040 6480464 Arsenic Trioxide results in decreased phosphorylation of ATM protein CTD PMID:31597699 arsenous acid decreases expression ISO RGD:1593265 6480464 Arsenic Trioxide results in decreased expression of ATM mRNA CTD PMID:19730151 arsenous acid increases phosphorylation ISO RGD:1593265 6480464 Arsenic Trioxide results in increased phosphorylation of ATM protein CTD PMID:23337567 arsenous acid multiple interactions ISO RGD:1606040 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in increased phosphorylation of ATM protein, Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of ATM mRNA] CTD PMID:29274334 , PMID:30012499 arsenous acid increases expression ISO RGD:1606040 6480464 Arsenic Trioxide results in increased expression of ATM mRNA CTD PMID:29274334 asbestos affects expression ISO RGD:1606040 6480464 Asbestos affects the expression of ATM mRNA CTD PMID:17297452 asbestos affects response to substance ISO RGD:1606040 6480464 ATM alternative form affects the susceptibility to Asbestos CTD PMID:28687356 atrazine multiple interactions EXP 6480464 [Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of ATM mRNA CTD PMID:22515965 benzo[a]pyrene decreases expression ISO RGD:1606040 6480464 Benzo(a)pyrene results in decreased expression of ATM mRNA CTD PMID:20064835 benzo[a]pyrene affects methylation ISO RGD:1606040 6480464 Benzo(a)pyrene affects the methylation of ATM promoter CTD PMID:27901495 benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of ATM exon, Benzo(a)pyrene results in increased methylation of ATM intron CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO RGD:1606040 6480464 [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of ATM mRNA more ... CTD PMID:21882252 more ... benzo[a]pyrene affects response to substance ISO RGD:1606040 6480464 ATM protein affects the susceptibility to Benzo(a)pyrene CTD PMID:22382310 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of ATM mRNA CTD PMID:20713471 , PMID:22228805 benzo[a]pyrene multiple interactions EXP 6480464 ATM protein affects the susceptibility to [Caffeine co-treated with Benzo(a)pyrene], ATM protein affects the susceptibility to [wortmannin co-treated with Benzo(a)pyrene] CTD PMID:20888899 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of ATM mRNA CTD PMID:19770486 benzo[a]pyrene increases expression ISO RGD:1606040 6480464 Benzo(a)pyrene results in increased expression of ATM mRNA, Benzo(a)pyrene results in increased expression of ATM protein CTD PMID:17879257 , PMID:22266578 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1606040 6480464 7 more ... CTD PMID:20018196 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1606040 6480464 7 more ... CTD PMID:28593498 bexarotene increases activity ISO RGD:1606040 6480464 bexarotene results in increased activity of ATM protein CTD PMID:19067706 bis(2-chloroethyl) sulfide multiple interactions ISO RGD:1606040 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased phosphorylation of ATM protein], wortmannin inhibits the reaction [Mustard Gas results in increased phosphorylation of ATM protein] CTD PMID:22119920 bis(2-chloroethyl) sulfide increases phosphorylation ISO RGD:1606040 6480464 Mustard Gas results in increased phosphorylation of ATM protein CTD PMID:22119920 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1593265 6480464 Diethylhexyl Phthalate results in increased expression of ATM mRNA CTD PMID:28115068 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1606040 6480464 Diethylhexyl Phthalate inhibits the reaction [Camptothecin results in increased expression of ATM protein modified form], ESR1 promotes the reaction [Diethylhexyl Phthalate inhibits the reaction [Camptothecin results in increased expression of ATM protein modified form]] CTD PMID:30720231 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of ATM mRNA CTD PMID:29385306 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1593265 6480464 Ethanol promotes the reaction [Diethylhexyl Phthalate results in increased expression of ATM mRNA], PQQ Cofactor inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ATM mRNA] CTD PMID:28115068 bisphenol A decreases expression ISO RGD:1593265 6480464 bisphenol A results in decreased expression of ATM mRNA CTD PMID:25181051 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ATM mRNA CTD PMID:35598803 bisphenol A increases phosphorylation ISO RGD:1606040 6480464 bisphenol A results in increased phosphorylation of ATM protein CTD PMID:29275510 bisphenol A increases expression ISO RGD:1593265 6480464 bisphenol A results in increased expression of ATM mRNA CTD PMID:27208089 , PMID:27571134 bisphenol A increases phosphorylation ISO RGD:1593265 6480464 bisphenol A results in increased phosphorylation of ATM protein CTD PMID:27208089 bisphenol A increases activity ISO RGD:1593265 6480464 bisphenol A results in increased activity of ATM protein CTD PMID:24085620 bisphenol A multiple interactions ISO RGD:1606040 6480464 [naringenin co-treated with bisphenol A] results in increased expression of ATM mRNA more ... CTD PMID:25933419 , PMID:36235125 bisphenol A increases expression ISO RGD:1606040 6480464 bisphenol A results in increased expression of ATM protein modified form CTD PMID:25933419 bleomycin A2 multiple interactions ISO RGD:1606040 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]] more ... CTD PMID:24933654 bleomycin A2 increases phosphorylation ISO RGD:1606040 6480464 Bleomycin results in increased phosphorylation of ATM protein CTD PMID:24933654 bortezomib multiple interactions ISO RGD:1606040 6480464 [CASP8 protein results in increased activity of CASP3 protein] affects the reaction [Bortezomib results in increased cleavage of ATM protein], benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Bortezomib results in increased cleavage of ATM protein] CTD PMID:12393500 bortezomib increases cleavage ISO RGD:1606040 6480464 Bortezomib results in increased cleavage of ATM protein CTD PMID:12393500 Brevetoxin B increases expression ISO RGD:1606040 6480464 brevetoxin 2 results in increased expression of ATM mRNA CTD PMID:20498034 bromoacetate increases expression ISO RGD:1606040 6480464 bromoacetate results in increased expression of ATM mRNA CTD PMID:19753638 busulfan multiple interactions ISO RGD:1606040 6480464 [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased phosphorylation of ATM protein CTD PMID:20933509 butanal decreases expression ISO RGD:1606040 6480464 butyraldehyde results in decreased expression of ATM mRNA CTD PMID:26079696 Butylbenzyl phthalate increases expression EXP 6480464 butylbenzyl phthalate results in increased expression of ATM protein CTD PMID:31212022 Butylbenzyl phthalate multiple interactions ISO RGD:1606040 6480464 ATM protein affects the reaction [butylbenzyl phthalate results in increased expression of ZEB1 protein] CTD PMID:31212022 Butylbenzyl phthalate increases expression ISO RGD:1606040 6480464 butylbenzyl phthalate results in increased expression of ATM protein CTD PMID:31212022 Butylparaben affects expression ISO RGD:1606040 6480464 butylparaben affects the expression of ATM mRNA CTD PMID:24481588 cadmium dichloride decreases expression ISO RGD:1606040 6480464 Cadmium Chloride results in decreased expression of ATM mRNA CTD PMID:26525392 cadmium dichloride increases expression ISO RGD:1606040 6480464 Cadmium Chloride results in increased expression of ATM mRNA CTD PMID:26472689 caffeine multiple interactions ISO RGD:1606040 6480464 [[Caffeine results in decreased activity of ATR protein] co-treated with [Caffeine results in decreased activity of ATM protein]] results in decreased susceptibility to Acrylamide more ... CTD PMID:15975956 more ... caffeine decreases phosphorylation ISO RGD:1606040 6480464 Caffeine results in decreased phosphorylation of ATM protein CTD PMID:35688186 caffeine multiple interactions EXP 6480464 ATM protein affects the susceptibility to [Caffeine co-treated with Benzo(a)pyrene] CTD PMID:20888899 caffeine decreases activity ISO RGD:1606040 6480464 Caffeine results in decreased activity of ATM protein CTD PMID:10531013 , PMID:11507241 calcitriol increases expression ISO RGD:1606040 6480464 Calcitriol results in increased expression of ATM mRNA CTD PMID:16002434 camptothecin decreases expression ISO RGD:1606040 6480464 Camptothecin results in decreased expression of ATM mRNA CTD PMID:24792648 camptothecin increases activity ISO RGD:1593265 10053571 camptothecin increases kinase activity in rat cerebellar granule neurons RGD camptothecin multiple interactions ISO RGD:1606040 6480464 Diethylhexyl Phthalate inhibits the reaction [Camptothecin results in increased expression of ATM protein modified form], ESR1 promotes the reaction [Diethylhexyl Phthalate inhibits the reaction [Camptothecin results in increased expression of ATM protein modified form]] CTD PMID:30720231 camptothecin increases expression ISO RGD:1606040 6480464 Camptothecin results in increased expression of ATM protein modified form CTD PMID:30720231 cannabidiol multiple interactions ISO RGD:1606040 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of ATM mRNA CTD PMID:30096889 cannabidiol increases expression ISO RGD:1606040 6480464 Cannabidiol results in increased expression of ATM protein CTD PMID:31349651 capsaicin multiple interactions ISO RGD:1606040 6480464 3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein] more ... CTD PMID:22226932 capsaicin increases phosphorylation ISO RGD:1606040 6480464 Capsaicin results in increased phosphorylation of ATM protein CTD PMID:19502594 capsaicin increases expression ISO RGD:1606040 6480464 Capsaicin results in increased expression of ATM mRNA CTD PMID:19502594 capsaicin increases activity ISO RGD:1606040 6480464 Capsaicin results in increased activity of ATM protein CTD PMID:19502594 carbamate ester increases phosphorylation ISO RGD:1606040 6480464 Carbamates analog results in increased phosphorylation of ATM protein CTD PMID:19111005 carbamate ester multiple interactions ISO RGD:1606040 6480464 Carbamates analog promotes the reaction [ATM protein results in increased phosphorylation of and results in increased activity of TP53 protein], Carbamates analog results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:19376255 carbon nanotube increases expression ISO RGD:1606040 6480464 Nanotubes, Carbon results in increased expression of ATM mRNA CTD PMID:17450800 carbon nanotube decreases expression ISO RGD:1606040 6480464 Nanotubes, Carbon results in decreased expression of ATM mRNA CTD PMID:29426343 carbon nanotube decreases methylation ISO RGD:1606040 6480464 Nanotubes, Carbon results in decreased methylation of ATM gene CTD PMID:30990028 casticin decreases expression ISO RGD:1606040 6480464 casticin results in decreased expression of ATM protein CTD PMID:29098808 CCCP increases phosphorylation ISO RGD:1606040 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of ATM protein CTD PMID:29660402 CCCP multiple interactions ISO RGD:1606040 6480464 ATM protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein], Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein] CTD PMID:29660402 CGP 52608 multiple interactions ISO RGD:1606040 6480464 CGP 52608 promotes the reaction [RORA protein binds to ATM gene] CTD PMID:28238834 chlordecone increases expression EXP 6480464 Chlordecone results in increased expression of ATM mRNA CTD PMID:33711761 chloroquine increases phosphorylation ISO RGD:1606040 6480464 Chloroquine results in increased phosphorylation of ATM protein CTD PMID:18089834 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of ATM mRNA CTD PMID:22515965 chlorpyrifos multiple interactions EXP 6480464 [Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of ATM mRNA CTD PMID:22515965 chromium(6+) multiple interactions ISO RGD:1606040 6480464 chromium hexavalent ion affects the phosphorylation of and affects the expression of ATM protein CTD PMID:25173789 chromium(6+) multiple interactions EXP 6480464 [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein, Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein] CTD PMID:35643323 cisplatin increases expression ISO RGD:1606040 6480464 Cisplatin results in increased expression of ATM mRNA, Cisplatin results in increased expression of ATM protein modified form CTD PMID:21184746 , PMID:25450742 cisplatin increases expression ISO RGD:1593265 6480464 Cisplatin results in increased expression of ATM protein modified form CTD PMID:26739623 cisplatin multiple interactions ISO RGD:1593265 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of ATM protein modified form] CTD PMID:26739623 cisplatin multiple interactions EXP 6480464 [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Cisplatin results in increased phosphorylation of TRIM28 protein] more ... CTD PMID:22003191 , PMID:26723870 cisplatin increases phosphorylation EXP 6480464 Cisplatin results in increased phosphorylation of ATM protein CTD PMID:22006019 , PMID:35842499 cisplatin increases response to substance ISO RGD:1606040 6480464 ATM protein results in increased susceptibility to Cisplatin CTD PMID:21324906 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of ATM mRNA, Cisplatin results in increased expression of ATM protein CTD PMID:21151649 , PMID:26723870 cisplatin multiple interactions ISO RGD:1606040 6480464 [Cisplatin results in increased phosphorylation of TP63 protein alternative form] promotes the reaction [TP63 protein alternative form binds to ATM promoter] more ... CTD PMID:20145152 , PMID:21191146 clofarabine multiple interactions ISO RGD:1606040 6480464 [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased phosphorylation of ATM protein CTD PMID:20933509 cobalt atom increases expression EXP 6480464 Cobalt results in increased expression of ATM mRNA CTD PMID:22147119 cocaine multiple interactions EXP 6480464 EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA] CTD PMID:20056891 cocaine increases expression EXP 6480464 Cocaine results in increased expression of ATM mRNA CTD PMID:20056891 copper atom multiple interactions ISO RGD:1606040 6480464 [Chelating Agents binds to Copper] which results in increased expression of ATM mRNA, [ethyl maltol results in increased susceptibility to [Copper Sulfate results in increased abundance of Copper]] which results in increased phosphorylation of ATM protein CTD PMID:30911355 , PMID:33271249 copper(0) multiple interactions ISO RGD:1606040 6480464 [Chelating Agents binds to Copper] which results in increased expression of ATM mRNA, [ethyl maltol results in increased susceptibility to [Copper Sulfate results in increased abundance of Copper]] which results in increased phosphorylation of ATM protein CTD PMID:30911355 , PMID:33271249 copper(II) chloride multiple interactions ISO RGD:1606040 6480464 cupric chloride results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 copper(II) sulfate decreases expression ISO RGD:1606040 6480464 Copper Sulfate results in decreased expression of ATM mRNA CTD PMID:19549813 copper(II) sulfate multiple interactions ISO RGD:1606040 6480464 [ethyl maltol results in increased susceptibility to [Copper Sulfate results in increased abundance of Copper]] which results in increased phosphorylation of ATM protein CTD PMID:33271249 crocidolite asbestos decreases expression ISO RGD:1606040 6480464 Asbestos, Crocidolite results in decreased expression of ATM mRNA CTD PMID:29523930 Cuprizon decreases expression ISO RGD:1593265 6480464 Cuprizone results in decreased expression of ATM mRNA CTD PMID:26577399 curcumin multiple interactions ISO RGD:1606040 6480464 [Isoflavones co-treated with Curcumin] results in increased phosphorylation of ATM protein CTD PMID:21134073 curcumin increases phosphorylation ISO RGD:1606040 6480464 Curcumin results in increased phosphorylation of ATM protein CTD PMID:19401701 , PMID:21134073 cyclosporin A decreases expression ISO RGD:1606040 6480464 Cyclosporine results in decreased expression of ATM mRNA CTD PMID:25562108 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of ATM mRNA CTD PMID:21142847 cyproconazole multiple interactions ISO RGD:1593265 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of ATM mRNA CTD PMID:29038839 daunorubicin increases expression ISO RGD:1606040 6480464 Daunorubicin results in increased expression of ATM mRNA CTD PMID:12656675 Decamethylcyclopentasiloxane decreases expression ISO RGD:1606040 6480464 decamethylcyclopentasiloxane results in decreased expression of ATM mRNA CTD PMID:27601420 deguelin decreases expression ISO RGD:1606040 6480464 deguelin results in decreased expression of ATM mRNA CTD PMID:22227970 desferrioxamine B multiple interactions ISO RGD:1606040 6480464 Deferoxamine results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 diarsenic trioxide decreases expression ISO RGD:1606040 6480464 Arsenic Trioxide results in decreased expression of ATM mRNA, Arsenic Trioxide results in decreased expression of ATM protein modified form CTD PMID:19763917 more ... diarsenic trioxide decreases phosphorylation ISO RGD:1606040 6480464 Arsenic Trioxide results in decreased phosphorylation of ATM protein CTD PMID:31597699 diarsenic trioxide increases expression ISO RGD:1606040 6480464 Arsenic Trioxide results in increased expression of ATM mRNA CTD PMID:29274334 diarsenic trioxide multiple interactions ISO RGD:1606040 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in increased phosphorylation of ATM protein, Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of ATM mRNA] CTD PMID:29274334 , PMID:30012499 diarsenic trioxide increases phosphorylation ISO RGD:1593265 6480464 Arsenic Trioxide results in increased phosphorylation of ATM protein CTD PMID:23337567 diarsenic trioxide decreases expression ISO RGD:1593265 6480464 Arsenic Trioxide results in decreased expression of ATM mRNA CTD PMID:19730151 diazinon increases methylation ISO RGD:1606040 6480464 Diazinon results in increased methylation of ATM gene CTD PMID:22964155 diazinon affects expression ISO RGD:1593265 6480464 Diazinon affects the expression of ATM mRNA CTD PMID:22546817 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of ATM mRNA CTD PMID:17361019 more ... dichlorvos multiple interactions ISO RGD:1593265 6480464 TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ATM mRNA] CTD PMID:24369695 dichlorvos increases expression ISO RGD:1593265 6480464 Dichlorvos results in increased expression of ATM mRNA, Dichlorvos results in increased expression of ATM protein CTD PMID:24369695 dicoumarol multiple interactions ISO RGD:1606040 6480464 Dicumarol inhibits the reaction [2 more ... CTD PMID:26630137 dicrotophos decreases expression ISO RGD:1606040 6480464 dicrotophos results in decreased expression of ATM mRNA CTD PMID:28302478 dieldrin affects expression ISO RGD:1593265 6480464 Dieldrin affects the expression of ATM mRNA CTD PMID:22546817 diepoxybutane multiple interactions ISO RGD:1606040 6480464 ATM protein affects the reaction [diepoxybutane results in increased phosphorylation of TP53 protein] CTD PMID:20024960 diepoxybutane increases phosphorylation EXP 6480464 diepoxybutane results in increased phosphorylation of ATM protein CTD PMID:25633853 diepoxybutane increases response to substance ISO RGD:1606040 6480464 ATM protein results in increased susceptibility to diepoxybutane CTD PMID:20024960 diethyl maleate increases expression ISO RGD:1606040 6480464 diethyl maleate results in increased expression of ATM mRNA CTD PMID:11875189 dihydroxyacetone decreases expression ISO RGD:1606040 6480464 Dihydroxyacetone results in decreased expression of ATM mRNA CTD PMID:32506039 disodium selenite increases phosphorylation ISO RGD:1606040 6480464 Sodium Selenite results in increased phosphorylation of ATM protein CTD PMID:36113632 dorsomorphin increases phosphorylation ISO RGD:1606040 6480464 dorsomorphin results in increased phosphorylation of ATM protein CTD PMID:23274516 dorsomorphin multiple interactions ISO RGD:1606040 6480464 Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of ATM protein], Caffeine inhibits the reaction [dorsomorphin results in increased phosphorylation of ATM protein] CTD PMID:23274516 doxorubicin multiple interactions ISO RGD:1606040 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Doxorubicin results in increased activity of ATM protein] more ... CTD PMID:15489221 more ... doxorubicin multiple interactions ISO RGD:1593265 6480464 [Poly(ADP-ribose) Polymerase Inhibitors co-treated with Doxorubicin] results in increased phosphorylation of ATM protein CTD PMID:29913208 doxorubicin decreases expression ISO RGD:1606040 6480464 Doxorubicin results in decreased expression of ATM mRNA CTD PMID:22832221 doxorubicin increases activity ISO RGD:1606040 6480464 Doxorubicin results in increased activity of ATM protein CTD PMID:22927544 doxorubicin multiple interactions EXP 6480464 Doxorubicin results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:22242153 doxorubicin increases phosphorylation ISO RGD:1606040 6480464 Doxorubicin results in increased phosphorylation of ATM protein CTD PMID:15489221 doxorubicin increases expression ISO RGD:1606040 6480464 Doxorubicin results in increased expression of ATM mRNA, Doxorubicin results in increased expression of ATM protein modified form CTD PMID:21184746 , PMID:34783124 emodin increases expression ISO RGD:1606040 6480464 Emodin results in increased expression of ATM mRNA CTD PMID:16045814 emodin increases phosphorylation ISO RGD:1606040 6480464 Emodin results in increased phosphorylation of ATM protein CTD PMID:20855424 endosulfan multiple interactions EXP 6480464 [Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of ATM mRNA CTD PMID:22515965 endosulfan affects expression ISO RGD:1606040 6480464 Endosulfan affects the expression of ATM mRNA CTD PMID:29705383 endosulfan increases expression ISO RGD:1606040 6480464 Endosulfan results in increased expression of ATM mRNA, Endosulfan results in increased expression of ATM protein CTD PMID:29705383 , PMID:30090376 endosulfan multiple interactions ISO RGD:1606040 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Endosulfan affects the expression of ATM mRNA] CTD PMID:29705383 epoxiconazole increases expression ISO RGD:1593265 6480464 epoxiconazole results in increased expression of ATM mRNA CTD PMID:29038839 epoxiconazole multiple interactions ISO RGD:1593265 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of ATM mRNA CTD PMID:29038839 erlotinib hydrochloride multiple interactions ISO RGD:1606040 6480464 Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of ATM mRNA] CTD PMID:29274334 ethanol multiple interactions ISO RGD:1593265 6480464 Ethanol promotes the reaction [Diethylhexyl Phthalate results in increased expression of ATM mRNA] CTD PMID:28115068 Ethyl maltol multiple interactions ISO RGD:1606040 6480464 [ethyl maltol results in increased susceptibility to [Copper Sulfate results in increased abundance of Copper]] which results in increased phosphorylation of ATM protein CTD PMID:33271249 etoposide multiple interactions EXP 6480464 Etoposide results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:22242153 etoposide multiple interactions ISO RGD:1606040 6480464 Etoposide results in increased phosphorylation of and affects the localization of ATM protein, pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of and affects the localization of ATM protein] CTD PMID:26259609 fenhexamid increases expression ISO RGD:1606040 6480464 N-(2, 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of ATM mRNA CTD PMID:25461557 fenthion decreases expression EXP 6480464 Fenthion results in decreased expression of ATM mRNA CTD PMID:34813904 flavanones increases phosphorylation ISO RGD:1606040 6480464 Flavanones results in increased phosphorylation of ATM protein CTD PMID:21616090 folic acid affects expression ISO RGD:1606040 6480464 Folic Acid affects the expression of ATM mRNA CTD PMID:16361273 formaldehyde increases expression ISO RGD:1606040 6480464 Formaldehyde results in increased expression of ATM mRNA CTD PMID:22525295 furan increases expression ISO RGD:1593265 6480464 furan results in increased expression of ATM mRNA CTD PMID:22079235 furan decreases expression ISO RGD:1593265 6480464 furan results in decreased expression of ATM mRNA CTD PMID:25539665 furosemide affects expression ISO RGD:1593265 6480464 Furosemide affects the expression of ATM mRNA CTD PMID:17497460 gadodiamide hydrate increases expression ISO RGD:1606040 6480464 gadodiamide results in increased expression of ATM mRNA CTD PMID:20959327 gallic acid decreases expression ISO RGD:1606040 6480464 Gallic Acid results in decreased expression of ATM mRNA CTD PMID:21887735 , PMID:34408198 geneticin increases expression ISO RGD:1606040 6480464 antibiotic G 418 results in increased expression of ATM protein mutant form CTD PMID:15498871 genistein increases phosphorylation ISO RGD:1606040 6480464 Genistein results in increased phosphorylation of ATM protein CTD PMID:15177039 , PMID:19038232 genistein affects response to substance EXP 6480464 ATM protein affects the susceptibility to Genistein CTD PMID:21177254 genistein multiple interactions ISO RGD:1606040 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] more ... CTD PMID:15177039 , PMID:19038232 gentamycin increases expression ISO RGD:1606040 6480464 Gentamicins results in increased expression of ATM protein mutant form CTD PMID:15498871 gentamycin decreases expression ISO RGD:1593265 6480464 Gentamicins results in decreased expression of ATM mRNA CTD PMID:33387578 ginsenoside Rg1 multiple interactions ISO RGD:1606040 6480464 ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of ATM mRNA] CTD PMID:34783124 gold atom decreases expression ISO RGD:1606040 6480464 Gold analog results in decreased expression of ATM mRNA CTD PMID:36057382 gold(0) decreases expression ISO RGD:1606040 6480464 Gold analog results in decreased expression of ATM mRNA CTD PMID:36057382 hellebrigenin increases phosphorylation ISO RGD:1606040 6480464 hellebrigenin results in increased phosphorylation of ATM protein CTD PMID:24954031 hexamethylcyclotrisiloxane decreases expression ISO RGD:1606040 6480464 hexamethylcyclotrisiloxane results in decreased expression of ATM mRNA CTD PMID:27601420 hydrazine multiple interactions EXP 6480464 hydrazine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of ATM protein] CTD PMID:32142722 hydrogen peroxide affects expression ISO RGD:1606040 6480464 Hydrogen Peroxide affects the expression of ATM mRNA CTD PMID:21179406 hydrogen peroxide increases ADP-ribosylation ISO RGD:1606040 6480464 Hydrogen Peroxide results in increased ADP-ribosylation of ATM protein CTD PMID:30296409 hydrogen peroxide multiple interactions EXP 6480464 [Hydrogen Peroxide co-treated with N-(oxo-5 more ... CTD PMID:31494107 hydrogen peroxide increases phosphorylation ISO RGD:1606040 6480464 Hydrogen Peroxide results in increased phosphorylation of ATM protein CTD PMID:24933654 more ... hydrogen peroxide increases expression ISO RGD:1606040 6480464 Hydrogen Peroxide results in increased expression of ATM more ... CTD PMID:18951874 more ... hydrogen peroxide multiple interactions ISO RGD:1606040 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide promotes the reaction [Resveratrol results in increased phosphorylation of ATM protein]] more ... CTD PMID:24933654 more ... hydrogen peroxide decreases expression ISO RGD:1606040 6480464 Hydrogen Peroxide results in decreased expression of ATM mRNA CTD PMID:22539617 hydroxyurea increases expression EXP 6480464 Hydroxyurea results in increased expression of ATM mRNA CTD PMID:27208086 hydroxyurea multiple interactions ISO RGD:1606040 6480464 Doxorubicin inhibits the reaction [Nocodazole inhibits the reaction [Hydroxyurea results in increased phosphorylation of ATM protein]], Nocodazole inhibits the reaction [Hydroxyurea results in increased phosphorylation of ATM protein] CTD PMID:31597699 hydroxyurea increases phosphorylation ISO RGD:1606040 6480464 Hydroxyurea results in increased phosphorylation of ATM protein CTD PMID:31597699 irinotecan increases phosphorylation ISO RGD:1606040 6480464 Irinotecan results in increased phosphorylation of ATM protein CTD PMID:22898888 iron atom affects response to substance ISO RGD:1606040 6480464 ATM protein affects the susceptibility to Iron CTD PMID:16959548 iron atom affects abundance EXP 6480464 ATM protein affects the abundance of Iron CTD PMID:15336622 iron atom multiple interactions ISO RGD:1606040 6480464 Iron results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 iron trichloride multiple interactions ISO RGD:1606040 6480464 ferric chloride results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 iron(0) affects response to substance ISO RGD:1606040 6480464 ATM protein affects the susceptibility to Iron CTD PMID:16959548 iron(0) affects abundance EXP 6480464 ATM protein affects the abundance of Iron CTD PMID:15336622 iron(0) multiple interactions ISO RGD:1606040 6480464 Iron results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 isocyanates increases phosphorylation EXP 6480464 [Isocyanates results in increased phosphorylation of ATM protein] which results in increased phosphorylation of H2AX protein, Isocyanates results in increased phosphorylation of ATM protein CTD PMID:19197993 isocyanates increases phosphorylation ISO RGD:1606040 6480464 Isocyanates analog results in increased phosphorylation of ATM protein CTD PMID:19111005 isocyanates increases expression ISO RGD:1606040 6480464 Isocyanates results in increased expression of ATM protein CTD PMID:19283680 isoflavones multiple interactions ISO RGD:1606040 6480464 [Isoflavones co-treated with Curcumin] results in increased phosphorylation of ATM protein CTD PMID:21134073 kaempferol multiple interactions ISO RGD:1606040 6480464 Caffeine inhibits the reaction [kaempferol results in increased phosphorylation of ATM protein] CTD PMID:19028473 kaempferol increases phosphorylation ISO RGD:1606040 6480464 kaempferol results in increased phosphorylation of ATM protein CTD PMID:19028473 kojic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA CTD PMID:17917374 L-ascorbic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA CTD PMID:17917374 L-ascorbic acid multiple interactions ISO RGD:1606040 6480464 Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of ATM protein modified form] CTD PMID:25977998 Lasiocarpine multiple interactions ISO RGD:1606040 6480464 [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ATM mRNA CTD PMID:33884520 lead diacetate multiple interactions ISO RGD:1606040 6480464 ATM protein affects the reaction [lead acetate results in decreased expression of COX4 protein], lead acetate promotes the reaction [PINK1 protein binds to ATM protein] CTD PMID:29660402 lead diacetate increases phosphorylation EXP 6480464 lead acetate results in increased phosphorylation of ATM protein CTD PMID:29660402 lead diacetate increases phosphorylation ISO RGD:1606040 6480464 lead acetate results in increased phosphorylation of ATM protein CTD PMID:29660402 Licochalcone B increases phosphorylation ISO RGD:1606040 6480464 licochalcone B results in increased phosphorylation of ATM protein CTD PMID:35948134 lithium atom decreases expression ISO RGD:1606040 6480464 Lithium results in decreased expression of ATM mRNA CTD PMID:19949822 lithium hydride decreases expression ISO RGD:1606040 6480464 Lithium results in decreased expression of ATM mRNA CTD PMID:19949822 lovastatin multiple interactions ISO RGD:1593265 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of ATM protein modified form] CTD PMID:26739623 LY294002 multiple interactions ISO RGD:1606040 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] CTD PMID:19038232 manganese atom decreases expression ISO RGD:1606040 6480464 Manganese results in decreased expression of ATM mRNA CTD PMID:17175027 manganese(0) decreases expression ISO RGD:1606040 6480464 Manganese results in decreased expression of ATM mRNA CTD PMID:17175027 manganese(II) chloride decreases expression ISO RGD:1606040 6480464 manganese chloride results in decreased expression of ATM mRNA CTD PMID:17175027 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein] CTD PMID:35643323 metformin affects response to substance ISO RGD:1606040 6480464 ATM gene SNP affects the susceptibility to Metformin CTD PMID:21186350 metformin increases expression ISO RGD:1606040 150404268 Metformin increases expression of ATM protein in epithelial cell of alveolus of lung RGD methidathion decreases expression EXP 6480464 methidathion results in decreased expression of ATM mRNA CTD PMID:34813904 methotrexate decreases response to substance EXP 6480464 ATM mRNA results in decreased susceptibility to Methotrexate, ATM protein results in decreased susceptibility to Methotrexate CTD PMID:16918715 methoxsalen multiple interactions ISO RGD:1606040 6480464 Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of ATM protein modified form] CTD PMID:23907605 methylparaben decreases expression ISO RGD:1606040 6480464 methylparaben results in decreased expression of ATM mRNA CTD PMID:24481588 mitoxantrone decreases expression ISO RGD:1606040 6480464 Mitoxantrone results in decreased expression of ATM mRNA CTD PMID:22832221 mitoxantrone multiple interactions ISO RGD:1593265 6480464 [Poly(ADP-ribose) Polymerase Inhibitors co-treated with Mitoxantrone] results in increased phosphorylation of ATM protein CTD PMID:29913208 mitoxantrone increases phosphorylation ISO RGD:1593265 6480464 Mitoxantrone results in increased phosphorylation of ATM protein CTD PMID:29913208 monocrotaline multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA, [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein CTD PMID:21224054 monocrotaline multiple interactions ISO RGD:1606040 6480464 [CYP3A4 protein results in increased metabolism of Monocrotaline] which results in increased expression of ATM mRNA CTD PMID:33884520 motexafin gadolinium multiple interactions ISO RGD:1606040 6480464 motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of ATM mRNA] CTD PMID:16357179 motexafin gadolinium increases expression ISO RGD:1606040 6480464 motexafin gadolinium results in increased expression of ATM mRNA CTD PMID:16357179 myristicin decreases expression ISO RGD:1606040 6480464 myristicin results in decreased expression of ATM mRNA CTD PMID:24792648 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:1606040 6480464 N more ... CTD PMID:33645215 N-acetyl-L-cysteine multiple interactions ISO RGD:1606040 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:15489221 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:1593265 6480464 Acetylcysteine affects the reaction [yttrium chloride affects the expression of ATM protein] CTD PMID:35088107 N-acetyl-L-cysteine increases phosphorylation ISO RGD:1606040 6480464 Acetylcysteine results in increased phosphorylation of ATM protein CTD PMID:31715134 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of ATM protein] CTD PMID:32142722 N-methyl-N'-nitro-N-nitrosoguanidine increases response to substance EXP 6480464 ATM gene mutant form results in increased susceptibility to Methylnitronitrosoguanidine CTD PMID:15010311 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA more ... CTD PMID:17854601 more ... N-nitrosodiethylamine decreases expression ISO RGD:1593265 6480464 Diethylnitrosamine results in decreased expression of ATM protein CTD PMID:11751435 N-nitrosodiethylamine decreases activity ISO RGD:1593265 6480464 Diethylnitrosamine results in decreased activity of ATM protein CTD PMID:11751435 N-nitrosodiethylamine multiple interactions ISO RGD:1593265 6480464 ATM protein affects the reaction [Diethylnitrosamine results in increased expression of TP53 protein] CTD PMID:11751435 N-nitrosodiethylamine increases phosphorylation EXP 6480464 Diethylnitrosamine results in increased phosphorylation of ATM protein CTD PMID:18506893 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of ATM mRNA CTD PMID:17854601 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of ATM mRNA CTD PMID:12426141 , PMID:12839937 nickel dichloride affects expression ISO RGD:1593265 6480464 nickel chloride affects the expression of ATM mRNA CTD PMID:22546817 nicotine multiple interactions ISO RGD:1606040 6480464 Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of ATM protein modified form] CTD PMID:23907605 nitenpyram increases expression ISO RGD:1606040 6480464 nitenpyram results in increased expression of ATM mRNA CTD PMID:35568224 nitrates increases expression ISO RGD:1593265 6480464 Nitrates results in increased expression of ATM mRNA CTD PMID:30022042 nocodazole multiple interactions ISO RGD:1606040 6480464 Doxorubicin inhibits the reaction [Nocodazole inhibits the reaction [Hydroxyurea results in increased phosphorylation of ATM protein]], Nocodazole inhibits the reaction [Hydroxyurea results in increased phosphorylation of ATM protein] CTD PMID:31597699 O-methyleugenol decreases expression ISO RGD:1593265 6480464 methyleugenol results in decreased expression of ATM mRNA CTD PMID:26011634 O-methyleugenol increases phosphorylation ISO RGD:1606040 6480464 methyleugenol results in increased phosphorylation of ATM protein CTD PMID:28818686 octamethylcyclotetrasiloxane decreases expression ISO RGD:1606040 6480464 octamethylcyclotetrasiloxane results in decreased expression of ATM mRNA CTD PMID:27601420 ouabain increases phosphorylation ISO RGD:1606040 6480464 Ouabain results in increased phosphorylation of ATM protein CTD PMID:31436044 ozone increases expression ISO RGD:1606040 6480464 Ozone results in increased expression of ATM mRNA CTD PMID:27206323 ozone multiple interactions ISO RGD:1606040 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ATM mRNA more ... CTD PMID:32699268 p-menthan-3-ol decreases expression ISO RGD:1606040 6480464 Menthol results in decreased expression of ATM mRNA CTD PMID:26760959 paracetamol decreases expression ISO RGD:1606040 6480464 Acetaminophen results in decreased expression of ATM mRNA CTD PMID:21420995 paracetamol multiple interactions ISO RGD:1606040 6480464 2-(2 more ... CTD PMID:33971260 paracetamol increases phosphorylation ISO RGD:1606040 6480464 Acetaminophen results in increased phosphorylation of ATM protein CTD PMID:33971260 paraquat increases expression ISO RGD:1606040 6480464 Paraquat results in increased expression of ATM mRNA CTD PMID:20883675 paraquat multiple interactions EXP 6480464 [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of ATM mRNA CTD PMID:28012437 paromomycin increases expression ISO RGD:1606040 6480464 Paromomycin results in increased expression of ATM protein mutant form CTD PMID:15498871 PCB138 multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 pentamidine affects localization ISO RGD:1606040 6480464 Pentamidine affects the localization of ATM protein modified form CTD PMID:20144237 pentamidine decreases activity ISO RGD:1606040 6480464 Pentamidine results in decreased activity of ATM protein CTD PMID:20144237 pentanal decreases expression ISO RGD:1606040 6480464 pentanal results in decreased expression of ATM mRNA CTD PMID:26079696 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1606040 6480464 perfluorooctane sulfonic acid results in decreased expression of ATM mRNA CTD PMID:32790152 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ATM mRNA CTD PMID:36331819 perfluorooctanoic acid decreases expression ISO RGD:1606040 6480464 perfluorooctanoic acid results in decreased expression of ATM mRNA CTD PMID:32790152 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of ATM mRNA CTD PMID:23091169 phenytoin multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA, [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein CTD PMID:21224054 phosphoramide mustard affects expression ISO RGD:1593265 6480464 phosphoramide mustard affects the expression of ATM mRNA CTD PMID:25497287 phosphoramide mustard increases expression ISO RGD:1593265 6480464 phosphoramide mustard results in increased expression of ATM mRNA, phosphoramide mustard results in increased expression of ATM protein CTD PMID:25497287 , PMID:26708502 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of ATM mRNA CTD PMID:16985257 potassium bromate decreases expression ISO RGD:1606040 6480464 potassium bromate results in decreased expression of ATM mRNA CTD PMID:22539617 potassium chromate increases activity ISO RGD:1606040 6480464 potassium chromate(VI) results in increased activity of ATM protein CTD PMID:25977998 potassium chromate increases expression ISO RGD:1606040 6480464 potassium chromate(VI) results in increased expression of ATM protein modified form CTD PMID:25977998 potassium chromate multiple interactions ISO RGD:1606040 6480464 2-(2 more ... CTD PMID:25977998 Pranoprofen increases phosphorylation ISO RGD:1606040 6480464 pyranoprofen results in increased phosphorylation of ATM protein CTD PMID:31765691 prochloraz increases expression ISO RGD:1593265 6480464 prochloraz results in increased expression of ATM mRNA CTD PMID:29038839 promethazine decreases expression ISO RGD:1593265 6480464 Promethazine results in decreased expression of ATM mRNA CTD PMID:26011634 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of ATM mRNA CTD PMID:21278054 propylparaben affects expression ISO RGD:1606040 6480464 propylparaben affects the expression of ATM mRNA CTD PMID:24481588 pyrroloquinoline quinone multiple interactions ISO RGD:1593265 6480464 PQQ Cofactor inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ATM mRNA] CTD PMID:28115068 quercetin decreases expression ISO RGD:1606040 6480464 Quercetin results in decreased expression of ATM mRNA CTD PMID:20596804 , PMID:23727915 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of ATM mRNA CTD PMID:25862958 quercetin affects response to substance EXP 6480464 ATM protein affects the susceptibility to Quercetin CTD PMID:21177254 quercetin increases phosphorylation ISO RGD:1606040 6480464 Quercetin results in increased phosphorylation of ATM protein CTD PMID:15177039 , PMID:35688186 remdesivir increases phosphorylation ISO RGD:1606040 6480464 remdesivir results in increased phosphorylation of ATM protein CTD PMID:35417658 resveratrol multiple interactions ISO RGD:1606040 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of ATM protein]] more ... CTD PMID:15975956 more ... resveratrol decreases expression ISO RGD:1593265 6480464 Resveratrol results in decreased expression of ATM mRNA CTD PMID:33775663 resveratrol increases phosphorylation ISO RGD:1606040 6480464 resveratrol results in increased phosphorylation of ATM protein CTD PMID:23522185 , PMID:24933654 resveratrol increases activity ISO RGD:1606040 6480464 resveratrol results in increased activity of ATM protein CTD PMID:22029423 , PMID:23445485 resveratrol increases acetylation ISO RGD:1606040 6480464 resveratrol results in increased acetylation of ATM protein CTD PMID:25533949 rifampicin multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA, [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein CTD PMID:21224054 rifampicin decreases expression ISO RGD:1606040 6480464 Rifampin results in decreased expression of ATM mRNA CTD PMID:24552687 rotenone increases expression ISO RGD:1606040 6480464 Rotenone results in increased expression of ATM mRNA CTD PMID:18191903 rotenone decreases expression ISO RGD:1606040 6480464 Rotenone results in decreased expression of ATM mRNA CTD PMID:33512557 ruxolitinib multiple interactions ISO RGD:1606040 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in increased phosphorylation of ATM protein CTD PMID:30012499 S-nitrosoglutathione increases response to substance ISO RGD:1606040 6480464 ATM results in increased susceptibility to S-Nitrosoglutathione CTD PMID:8958160 silibinin multiple interactions ISO RGD:1606040 6480464 Silybin results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16777994 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of ATM mRNA CTD PMID:19073995 silicon dioxide decreases expression ISO RGD:1606040 6480464 Silicon Dioxide results in decreased expression of ATM mRNA CTD PMID:25351596 silver(1+) nitrate increases expression ISO RGD:1606040 6480464 Silver Nitrate analog results in increased expression of ATM mRNA CTD PMID:22831968 simvastatin multiple interactions ISO RGD:1606040 6480464 Simvastatin results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:20499237 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of ATM protein CTD PMID:18996350 sodium arsenite multiple interactions EXP 6480464 ATM protein affects the reaction [sodium arsenite results in decreased expression of HSP90AB1 mRNA], ATM protein affects the reaction [sodium arsenite results in increased phosphorylation of TRP53 protein] CTD PMID:18996350 sodium arsenite multiple interactions ISO RGD:1606040 6480464 ATM gene mutant form inhibits the reaction [sodium arsenite results in increased expression of CDKN1A protein], ATM gene mutant form inhibits the reaction [sodium arsenite results in increased expression of TP53 protein] CTD PMID:11507245 sodium arsenite increases response to substance ISO RGD:1606040 6480464 ATM gene mutant form results in increased susceptibility to sodium arsenite CTD PMID:11507245 sodium chromate decreases expression ISO RGD:1606040 6480464 sodium chromate(VI) results in decreased expression of ATM protein modified form CTD PMID:28318385 sodium chromate multiple interactions EXP 6480464 [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein, Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein] CTD PMID:35643323 sodium chromate multiple interactions ISO RGD:1606040 6480464 MUS81 protein mutant form inhibits the reaction [sodium chromate(VI) results in decreased expression of ATM protein modified form] CTD PMID:28318385 sodium fluoride increases expression ISO RGD:1606040 6480464 Sodium Fluoride results in increased expression of ATM mRNA CTD PMID:22525295 sterigmatocystin increases expression ISO RGD:1606040 6480464 Sterigmatocystin results in increased expression of ATM protein modified form CTD PMID:26914363 sterigmatocystin multiple interactions ISO RGD:1606040 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Sterigmatocystin results in increased expression of ATM protein modified form] CTD PMID:26914363 sunitinib increases expression ISO RGD:1606040 6480464 Sunitinib results in increased expression of ATM mRNA CTD PMID:31533062 T-2 toxin increases phosphorylation ISO RGD:1606040 6480464 T-2 Toxin results in increased phosphorylation of ATM protein CTD PMID:20150440 T-2 toxin decreases expression ISO RGD:1606040 6480464 T-2 Toxin results in decreased expression of ATM mRNA CTD PMID:34581912 temozolomide multiple interactions ISO RGD:1606040 6480464 [temozolomide co-treated with resveratrol] results in increased phosphorylation of ATM protein CTD PMID:23522185 temozolomide increases phosphorylation ISO RGD:1606040 6480464 temozolomide results in increased phosphorylation of ATM protein CTD PMID:23522185 testosterone affects expression EXP 6480464 Testosterone affects the expression of ATM mRNA CTD PMID:20403060 testosterone decreases expression ISO RGD:1606040 6480464 Testosterone results in decreased expression of ATM mRNA CTD PMID:33359661 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ATM mRNA CTD PMID:31919559 tetrachloromethane multiple interactions EXP 6480464 ATM mRNA inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased secretion of TGFB1 protein] more ... CTD PMID:36526012 thimerosal increases expression ISO RGD:1606040 6480464 Thimerosal results in increased expression of ATM mRNA CTD PMID:27188386 tributylstannane increases phosphorylation ISO RGD:1606040 6480464 tributyltin results in increased phosphorylation of ATM protein CTD PMID:36319700 tributylstannane multiple interactions ISO RGD:1606040 6480464 2-(2, 6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased phosphorylation of ATM protein] CTD PMID:36319700 tributylstannane increases phosphorylation EXP 6480464 tributyltin results in increased phosphorylation of ATM protein CTD PMID:36319700 trichostatin A increases expression ISO RGD:1606040 6480464 trichostatin A results in increased expression of ATM mRNA CTD PMID:24935251 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of ATM mRNA CTD PMID:28973697 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of ATM mRNA CTD PMID:35537566 tungsten decreases expression EXP 6480464 Tungsten results in decreased expression of ATM mRNA CTD PMID:30912803 usnic acid increases phosphorylation ISO RGD:1606040 6480464 usnic acid results in increased phosphorylation of ATM protein CTD PMID:31715134 usnic acid multiple interactions ISO RGD:1606040 6480464 Acetylcysteine inhibits the reaction [usnic acid results in increased phosphorylation of ATM protein] CTD PMID:31715134 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of ATM mRNA CTD PMID:17292431 valproic acid affects splicing ISO RGD:1593265 6480464 Valproic Acid affects the splicing of ATM mRNA CTD PMID:29427782 valproic acid decreases expression ISO RGD:1606040 6480464 Valproic Acid results in decreased expression of ATM mRNA CTD PMID:23179753 , PMID:27188386 valproic acid decreases methylation ISO RGD:1606040 6480464 Valproic Acid results in decreased methylation of ATM gene CTD PMID:29154799 veliparib multiple interactions ISO RGD:1606040 6480464 veliparib results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:21917757 veliparib increases activity ISO RGD:1606040 6480464 veliparib results in increased activity of ATM protein CTD PMID:21917757 vinclozolin increases expression ISO RGD:1593265 6480464 vinclozolin results in increased expression of ATM mRNA CTD PMID:23034163 vorinostat increases phosphorylation ISO RGD:1606040 6480464 vorinostat results in increased phosphorylation of ATM protein CTD PMID:20679231 vorinostat increases expression ISO RGD:1606040 6480464 vorinostat results in increased expression of ATM mRNA CTD PMID:27188386 wortmannin multiple interactions ISO RGD:1606040 6480464 wortmannin inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]], wortmannin inhibits the reaction [Mustard Gas results in increased phosphorylation of ATM protein] CTD PMID:15489221 , PMID:22119920 wortmannin multiple interactions EXP 6480464 ATM protein affects the susceptibility to [wortmannin co-treated with Benzo(a)pyrene] CTD PMID:20888899 yttrium chloride affects expression ISO RGD:1593265 6480464 yttrium chloride affects the expression of ATM protein CTD PMID:35088107 yttrium chloride multiple interactions ISO RGD:1593265 6480464 Acetylcysteine affects the reaction [yttrium chloride affects the expression of ATM protein] CTD PMID:35088107 zearalenone decreases expression EXP 6480464 Zearalenone results in decreased expression of ATM mRNA, Zearalenone results in decreased expression of ATM protein CTD PMID:29758222 zearalenone increases expression EXP 6480464 Zearalenone results in increased expression of ATM mRNA CTD PMID:27862621 zinc acetate multiple interactions ISO RGD:1606040 6480464 motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of ATM mRNA] CTD PMID:16357179 zinc acetate increases expression ISO RGD:1606040 6480464 Zinc Acetate results in increased expression of ATM mRNA CTD PMID:16357179 zinc atom decreases expression ISO RGD:1606040 6480464 Zinc results in decreased expression of ATM mRNA CTD PMID:19071009 zinc(0) decreases expression ISO RGD:1606040 6480464 Zinc results in decreased expression of ATM mRNA CTD PMID:19071009
