Atm (ataxia telangiectasia mutated) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Atm (ataxia telangiectasia mutated) Mus musculus
Analyze
Symbol: Atm
Name: ataxia telangiectasia mutated
RGD ID: 10199
MGI Page MGI
Description: Enables protein kinase activity. Involved in several processes, including cellular response to retinoic acid; negative regulation of TORC1 signaling; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within several processes, including DNA recombination; animal organ development; and meiotic nuclear division. Located in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and sensory organ. Used to study ataxia telangiectasia. Human ortholog(s) of this gene implicated in breast cancer; endometrial cancer; neurodegenerative disease (multiple); pancreatic cancer; and senile cataract. Orthologous to human ATM (ATM serine/threonine kinase); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; homologous recombination pathway of double-strand break repair; nuclear factor kappa B signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A-T mutated homolog; AI256621; ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated homolog; C030026E19Rik; serine-protein kinase ATM
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39953,348,422 - 53,448,125 (-)NCBIGRCm39mm39
GRCm39 Ensembl953,350,449 - 53,448,040 (-)Ensembl
GRCm38953,437,122 - 53,536,828 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl953,439,149 - 53,536,740 (-)EnsemblGRCm38mm10GRCm38
MGSCv37953,245,227 - 53,344,776 (-)NCBIGRCm37mm9NCBIm37
MGSCv36953,201,763 - 53,298,968 (-)NCBImm8
Celera950,696,862 - 50,796,451 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map929.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model