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Gene: Atm (ataxia telangiectasia mutated) Mus musculus
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Symbol: Atm
Name: ataxia telangiectasia mutated
RGD ID: 10199
Description: Exhibits protein kinase activity. Involved in several processes, including DNA recombination; animal organ development; and meiotic nuclear division. Localizes to spindle. Predicted to colocalize with chromosome, telomeric region. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and sensory organ. Used to study ataxia telangiectasia. Human ortholog(s) of this gene implicated in Parkinson's disease; ataxia telangiectasia; breast cancer; endometrial cancer; and pancreatic cancer. Orthologous to human ATM (ATM serine/threonine kinase); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; homologous recombination pathway of double-strand break repair; nuclear factor kappa B signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A-T mutated homolog; AI256621; ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated homolog; C030026E19Rik; serine-protein kinase ATM
Orthologs:
Homo sapiens (human) : ATM (ATM serine/threonine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atm (ATM serine/threonine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atm (ATM serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ATM (ATM serine/threonine kinase)
Canis lupus familiaris (dog) : ATM (ATM serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atm (ATM serine/threonine kinase)
Sus scrofa (pig) : ATM (ATM serine/threonine kinase)
Chlorocebus sabaeus (African green monkey) : ATM (ATM serine/threonine kinase)
Heterocephalus glaber (naked mole-rat) : Atm (ATM serine/threonine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl953,439,149 - 53,536,740 (-)EnsemblGRCm38mm10GRCm38
GRCm38953,437,122 - 53,536,828 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37953,245,227 - 53,344,776 (-)NCBIGRCm37mm9NCBIm37
MGSCv36953,201,763 - 53,298,968 (-)NCBImm8
Celera950,696,862 - 50,796,451 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map929.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model