ATM (ATM serine/threonine kinase) - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ATM (ATM serine/threonine kinase) Homo sapiens
Symbol: ATM
Name: ATM serine/threonine kinase
RGD ID: 1606040
HGNC Page HGNC:795
Description: Enables 1-phosphatidylinositol-3-kinase activity; DNA-dependent protein kinase activity; and identical protein binding activity. Involved in several processes, including cellular response to ionizing radiation; regulation of chromosome organization; and regulation of intracellular signal transduction. Located in chromosome, telomeric region; nucleolus; and nucleoplasm. Part of DNA repair complex. Is active in peroxisomal matrix and site of double-strand break. Implicated in several diseases, including breast cancer (multiple); endocrine gland cancer (multiple); lung carcinoma (multiple); neurodegenerative disease (multiple); and senile cataract. Biomarker of several diseases, including gastrointestinal system cancer (multiple); human immunodeficiency virus infectious disease; lung non-small cell carcinoma; oral mucosa leukoplakia; and prostate carcinoma in situ.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: A-T mutated; AT mutated; AT1; ATA; ataxia telangiectasia mutated; ataxia telangiectasia mutated (includes complementation groups A, C and D); ATC; ATD; ATDC; ATE; DKFZp781A0353; human phosphatidylinositol 3-kinase homolog; MGC74674; serine-protein kinase ATM; serine/threonine kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1; truncated ATM serine/threonine kinase
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3811108,223,067 - 108,369,102 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11108,222,804 - 108,369,102 (+)EnsemblGRCh38hg38GRCh38
GRCh3711108,093,794 - 108,239,829 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611107,598,769 - 107,745,036 (+)NCBINCBI36Build 36hg18NCBI36
Celera11105,248,510 - 105,394,764 (+)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11104,019,183 - 104,165,444 (+)NCBIHuRef
CHM1_111107,976,660 - 108,122,959 (+)NCBICHM1_1
T2T-CHM13v2.011108,230,362 - 108,376,596 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)