Sox17 (SRY (sex determining region Y)-box 17) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sox17 (SRY (sex determining region Y)-box 17) Mus musculus
Analyze
Symbol: Sox17
Name: SRY (sex determining region Y)-box 17
RGD ID: 1313359
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; beta-catenin binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including digestive tract morphogenesis; endodermal cell fate specification; and heart morphogenesis. Acts upstream of or within several processes, including circulatory system development; embryonic morphogenesis; and regulation of gene expression. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; early conceptus; and genitourinary system. Used to study biliary atresia. Human ortholog(s) of this gene implicated in intracranial aneurysm; patent ductus arteriosus; and vesicoureteral reflux. Orthologous to human SOX17 (SRY-box transcription factor 17).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Sox; SRY-box 17; SRY-box containing gene 17; transcription factor SOX-17
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914,561,154 - 4,567,624 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14,561,154 - 4,567,577 (-)EnsemblGRCm39 Ensembl
GRCm3814,490,928 - 4,497,426 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14,490,931 - 4,497,354 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714,481,009 - 4,486,494 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614,481,009 - 4,486,494 (-)NCBIMGSCv36mm8
Celera14,507,797 - 4,513,282 (-)NCBICelera
Cytogenetic Map1A1NCBI
cM Map11.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-bromo-2'-deoxyuridine  (ISO)
5-fluorouracil  (EXP,ISO)
6-aminonicotinamide  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acetic acid  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP)
angiotensin II  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
Benzo[k]fluoranthene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromochloroacetic acid  (EXP)
buta-1,3-diene  (EXP)
butanal  (ISO)
C60 fullerene  (ISO)
calciol  (EXP)
camptothecin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
CHIR 99021  (ISO)
Chlorophacinone  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP)
chrysene  (EXP)
columbamine  (ISO)
Cuprizon  (ISO)
diethylstilbestrol  (ISO)
dimethyl sulfoxide  (ISO)
diniconazole  (ISO)
dinoseb  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
fenvalerate  (ISO)
fluazinam  (ISO)
flusilazole  (ISO)
folic acid  (EXP)
gefitinib  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
hexaconazole  (ISO)
Indeno[1,2,3-cd]pyrene  (EXP)
isoprenaline  (EXP)
isotretinoin  (ISO)
lead(0)  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (EXP)
maleic acid  (ISO)
methamphetamine  (ISO)
mianserin  (ISO)
mifepristone  (ISO)
monocrotaline  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalene  (EXP)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
remdesivir  (EXP)
resveratrol  (ISO)
ritanserin  (ISO)
SB 431542  (ISO)
SCH 23390  (ISO)
silicon dioxide  (ISO)
sorafenib  (ISO)
sunitinib  (ISO)
tetrachloroethene  (EXP)
tetraphene  (EXP)
thalidomide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
topotecan  (ISO)
trichloroethene  (EXP,ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
valproic acid  (ISO)
vandetanib  (ISO)
vinclozolin  (ISO)
ziprasidone  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IGI)
cardiac cell fate determination  (ISO)
cardiogenic plate morphogenesis  (IMP)
cell migration involved in gastrulation  (IMP)
cellular response to leukemia inhibitory factor  (IDA)
common bile duct development  (IMP)
embryonic foregut morphogenesis  (IMP)
embryonic heart tube development  (IGI)
embryonic heart tube morphogenesis  (IMP)
embryonic organ development  (IMP)
endocardial cell differentiation  (IGI)
endocardium formation  (IGI)
endoderm development  (IMP)
endoderm formation  (ISO)
endodermal cell differentiation  (IDA)
endodermal cell fate determination  (IDA)
endodermal cell fate specification  (IMP)
endodermal digestive tract morphogenesis  (IMP)
gallbladder development  (IMP)
gastrulation  (IMP)
gene expression  (IMP)
heart development  (IMP)
heart looping  (IMP)
inner cell mass cellular morphogenesis  (IMP)
metanephros development  (ISO)
negative regulation of canonical Wnt signaling pathway  (IMP,ISO)
negative regulation of cell growth  (ISO)
negative regulation of Wnt signaling pathway  (IDA)
outflow tract morphogenesis  (IGI)
positive regulation of DNA-templated transcription  (IDA)
positive regulation of endodermal cell differentiation  (IDA)
positive regulation of gene expression  (IMP)
positive regulation of protein catabolic process  (IDA)
positive regulation of stem cell differentiation  (IMP)
positive regulation of transcription by RNA polymerase II  (IDA,IMP,ISO)
protein destabilization  (ISO)
protein stabilization  (ISO)
regulation of cardiac cell fate specification  (IMP)
regulation of cell differentiation  (IMP)
regulation of DNA-templated transcription  (IDA)
regulation of embryonic development  (IMP)
regulation of stem cell division  (IMP)
regulation of stem cell proliferation  (IDA)
regulation of transcription by RNA polymerase II  (IMP)
response to alkaloid  (ISO)
rostrocaudal neural tube patterning  (IMP)
signal transduction involved in regulation of gene expression  (IDA)
spermatogenesis  (IDA)
stem cell differentiation  (IMP)
stem cell fate specification  (IDA)
ureter development  (ISO)
vasculogenesis  (IGI)
Wnt signaling pathway  (IEA)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal aorta morphology  (IAGP)
abnormal artery morphology  (IAGP)
abnormal bile duct development  (IAGP)
abnormal blood vessel endothelium morphology  (IAGP)
abnormal common bile duct morphology  (IAGP)
abnormal cystic duct morphology  (IAGP)
abnormal embryo turning  (IAGP)
abnormal embryonic hematopoiesis  (IAGP)
abnormal endoderm development  (IAGP)
abnormal enzyme/coenzyme level  (IAGP)
abnormal extrahepatic bile duct morphology  (IAGP)
abnormal foregut morphology  (IAGP)
abnormal gallbladder epithelium morphology  (IAGP)
abnormal gallbladder morphology  (IAGP)
abnormal gallbladder physiology  (IAGP)
abnormal gallbladder size  (IAGP)
abnormal gallbladder smooth muscle morphology  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal hindgut morphology  (IAGP)
abnormal lipid metabolism  (IAGP)
abnormal liver development  (IAGP)
abnormal liver lobule morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal metabolism  (IAGP)
abnormal midgut morphology  (IAGP)
abnormal peroxisome morphology  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal thoracic aorta morphology  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
absent gallbladder  (IAGP)
absent pancreas  (IAGP)
aneurysm  (IAGP)
aortic dissection  (IAGP)
atrial septal defect  (IAGP)
biliary atresia  (IAGP)
cardiovascular system phenotype  (IAGP)
cholestasis  (IAGP)
decreased birth body size  (IAGP)
decreased body size  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased circulating HDL cholesterol level  (IAGP)
decreased circulating ketone body level  (IAGP)
decreased embryo size  (IAGP)
decreased endothelial cell proliferation  (IAGP)
decreased fasting circulating glucose level  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased liver weight  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
extrahepatic cholestasis  (IAGP)
failure of initiation of embryo turning  (IAGP)
gallbladder inflammation  (IAGP)
growth/size/body region phenotype  (IAGP)
hemorrhage  (IAGP)
increased bile salt level  (IAGP)
increased circulating alanine transaminase level  (IAGP)
increased circulating alkaline phosphatase level  (IAGP)
increased vascular permeability  (IAGP)
liver hypoplasia  (IAGP)
liver inflammation  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
ovary atrophy  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
reduced female fertility  (IAGP)
small gallbladder  (IAGP)
small heart  (IAGP)
spleen hypoplasia  (IAGP)
thin endoderm  (IAGP)
thrombocytopenia  (IAGP)
thymus hypoplasia  (IAGP)
truncated foregut  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Susceptibility loci for intracranial aneurysm in European and Japanese populations. Bilguvar K, etal., Nat Genet. 2008 Dec;40(12):1472-7. doi: 10.1038/ng.240. Epub 2008 Nov 9.
2. Differential gene expression profiling of cultured neu-transformed versus spontaneously-transformed rat cholangiocytes and of corresponding cholangiocarcinomas. Dumur CI, etal., Exp Mol Pathol. 2010 Dec;89(3):227-35. Epub 2010 Sep 9.
3. Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk. Foroud T, etal., Stroke. 2012 Nov;43(11):2846-52. doi: 10.1161/STROKEAHA.112.656397. Epub 2012 Sep 6.
4. Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Gräf S, etal., Nat Commun. 2018 Apr 12;9(1):1416. doi: 10.1038/s41467-018-03672-4.
5. Common genetic variants in pulmonary arterial hypertension. Gu S, etal., Lancet Respir Med. 2019 Mar;7(3):190-191. doi: 10.1016/S2213-2600(18)30448-X. Epub 2018 Dec 5.
6. Association of SOX17 Gene Polymorphisms and Intracranial Aneurysm: A Case-Control Study and Meta-Analysis. Hong EP, etal., World Neurosurg. 2018 Feb;110:e823-e829. doi: 10.1016/j.wneu.2017.11.108. Epub 2017 Nov 27.
7. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
8. Deficiency of endothelium-specific transcription factor Sox17 induces intracranial aneurysm. Lee S, etal., Circulation. 2015 Mar 17;131(11):995-1005. doi: 10.1161/CIRCULATIONAHA.114.012568. Epub 2015 Jan 16.
9. Associations among Genetic Variants and Intracranial Aneurysm in a Chinese Population. Li B, etal., Yonsei Med J. 2019 Jul;60(7):651-658. doi: 10.3349/ymj.2019.60.7.651.
10. Genetic polymorphisms in Sox17 associated with intracranial aneurysm in Chinese Han people: a genotype-phenotype study. Li M, etal., Neuropsychiatr Dis Treat. 2019 Apr 2;15:779-783. doi: 10.2147/NDT.S193478. eCollection 2019.
11. MGDs mouse GO annotations MGD data from the GO Consortium
12. MGD IEA MGD IEA
13. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. Sox17 Deficiency Promotes Pulmonary Arterial Hypertension via HGF/c-Met Signaling. Park CS, etal., Circ Res. 2022 Oct 28;131(10):792-806. doi: 10.1161/CIRCRESAHA.122.320845. Epub 2022 Oct 7.
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. Mouse MP Annotation Import Pipeline RGD automated import pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics. Sangam S, etal., Am J Respir Crit Care Med. 2023 Apr 15;207(8):1055-1069. doi: 10.1164/rccm.202203-0450OC.
21. SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension. Walters R, etal., Circulation. 2023 May 23;147(21):1606-1621. doi: 10.1161/CIRCULATIONAHA.122.061940. Epub 2023 Apr 17.
22. Upregulated miR-194-5p suppresses retinal microvascular endothelial cell dysfunction and mitigates the symptoms of hypertensive retinopathy in mice by targeting SOX17 and VEGF signaling. Wan Q, etal., Cell Cycle. 2023 Feb;22(3):331-346. doi: 10.1080/15384101.2022.2119514. Epub 2022 Oct 5.
23. SOX17 Loss-of-Function Mutation Underlying Familial Pulmonary Arterial Hypertension. Wang TM, etal., Int Heart J. 2021 May 29;62(3):566-574. doi: 10.1536/ihj.20-711. Epub 2021 May 1.
24. Dll4 Suppresses Transcytosis for Arterial Blood-Retinal Barrier Homeostasis. Yang JM, etal., Circ Res. 2020 Mar 13;126(6):767-783. doi: 10.1161/CIRCRESAHA.119.316476. Epub 2020 Feb 12.
25. Genome-wide association study of intracranial aneurysm identifies three new risk loci. Yasuno K, etal., Nat Genet. 2010 May;42(5):420-5. doi: 10.1038/ng.563. Epub 2010 Apr 4.
26. SOX17 loss-of-function variation underlying familial congenital heart disease. Zhao L, etal., Eur J Med Genet. 2021 May;64(5):104211. doi: 10.1016/j.ejmg.2021.104211. Epub 2021 Mar 29.
27. Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease. Zhu N, etal., Genome Med. 2018 Jul 20;10(1):56. doi: 10.1186/s13073-018-0566-x.
28. SOX17 is a Critical Factor in Maintaining Endothelial Function in Pulmonary Hypertension by an Exosome-Mediated Autocrine Manner. Zou X, etal., Adv Sci (Weinh). 2023 May;10(14):e2206139. doi: 10.1002/advs.202206139. Epub 2023 Mar 15.
Additional References at PubMed
PMID:8636240   PMID:8921394   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11291865   PMID:11410529   PMID:11973269   PMID:12117810   PMID:12477932   PMID:12659838   PMID:12815626  
PMID:14660441   PMID:14681479   PMID:15057272   PMID:15082719   PMID:15220343   PMID:15355796   PMID:15618518   PMID:16141072   PMID:16141073   PMID:16210401   PMID:16574095   PMID:16602821  
PMID:16895970   PMID:16988043   PMID:17151016   PMID:17328885   PMID:17360443   PMID:17609113   PMID:17610846   PMID:17655922   PMID:17875931   PMID:17882221   PMID:17940068   PMID:18287559  
PMID:18332127   PMID:18403408   PMID:18462699   PMID:18523156   PMID:18794329   PMID:19052383   PMID:19238729   PMID:19328208   PMID:19334288   PMID:19369396   PMID:19415628   PMID:19479035  
PMID:19515696   PMID:19515997   PMID:19548312   PMID:19549530   PMID:19619492   PMID:19786569   PMID:19896480   PMID:19913509   PMID:20059953   PMID:20123909   PMID:20133625   PMID:20228271  
PMID:20308546   PMID:20412781   PMID:20439489   PMID:20713518   PMID:20802155   PMID:20818615   PMID:21146513   PMID:21245162   PMID:21305474   PMID:21445260   PMID:21457403   PMID:21513905  
PMID:21873635   PMID:21896659   PMID:22121118   PMID:22132182   PMID:22344693   PMID:22412348   PMID:22510988   PMID:22581563   PMID:22589735   PMID:22627279   PMID:22638070   PMID:22659386  
PMID:22865702   PMID:22912418   PMID:22962592   PMID:22984607   PMID:22992956   PMID:23193166   PMID:23213408   PMID:23241958   PMID:23293295   PMID:23474895   PMID:23520114   PMID:23523683  
PMID:23537390   PMID:23584530   PMID:23604320   PMID:23728800   PMID:23747191   PMID:23747598   PMID:23823474   PMID:23824537   PMID:23824574   PMID:23884956   PMID:23918253   PMID:23951403  
PMID:23999170   PMID:24038996   PMID:24063807   PMID:24153254   PMID:24418654   PMID:24449835   PMID:24504341   PMID:24558432   PMID:24585447   PMID:24585688   PMID:24616493   PMID:24662049  
PMID:24755984   PMID:24812002   PMID:24835466   PMID:24859004   PMID:24952961   PMID:25091710   PMID:25141153   PMID:25144761   PMID:25209243   PMID:25209250   PMID:25340657   PMID:25371369  
PMID:25419850   PMID:25446530   PMID:25569111   PMID:25588837   PMID:25813538   PMID:25831528   PMID:25851587   PMID:25866973   PMID:25912690   PMID:26204127   PMID:26343328   PMID:26395490  
PMID:26418893   PMID:26494787   PMID:26534985   PMID:26630461   PMID:26864488   PMID:27053385   PMID:27072135   PMID:27102016   PMID:27217206   PMID:27241892   PMID:27246714   PMID:27348588  
PMID:27445154   PMID:27528602   PMID:27586544   PMID:27606604   PMID:27696611   PMID:27760115   PMID:28091527   PMID:28134930   PMID:28193997   PMID:28387645   PMID:28432216   PMID:28512199  
PMID:28552557   PMID:28577909   PMID:28619820   PMID:28743859   PMID:28844842   PMID:28854362   PMID:28870993   PMID:28890073   PMID:29023691   PMID:29217752   PMID:29397878   PMID:29412136  
PMID:29444818   PMID:29458175   PMID:29635272   PMID:29745895   PMID:29773646   PMID:29882512   PMID:29915126   PMID:29964027   PMID:30093553   PMID:30128894   PMID:30152028   PMID:30256721  
PMID:30356064   PMID:30458140   PMID:30472119   PMID:30504829   PMID:30530745   PMID:30568578   PMID:30591003   PMID:30604742   PMID:30635555   PMID:30735538   PMID:30913328   PMID:30928652  
PMID:31073164   PMID:31171776   PMID:31189761   PMID:31412026   PMID:31420575   PMID:31597657   PMID:31671403   PMID:31748268   PMID:31776260   PMID:31792383   PMID:31801081   PMID:31823782  
PMID:31836710   PMID:31996362   PMID:32001436   PMID:32392346   PMID:32433954   PMID:32478476   PMID:32499402   PMID:32891959   PMID:32921258   PMID:33095124   PMID:33127892   PMID:33246328  
PMID:33414188   PMID:33450185   PMID:33653874   PMID:33929320   PMID:34168324   PMID:34276786   PMID:34292881   PMID:34302955   PMID:34433966   PMID:34588579   PMID:35105859   PMID:35113719  
PMID:35171666   PMID:35177595   PMID:35444273   PMID:35649376   PMID:35729116   PMID:35831318   PMID:35918150   PMID:35988542   PMID:35998584   PMID:36007540   PMID:36046192   PMID:36123357  
PMID:36197846   PMID:36310172   PMID:36543770   PMID:36715213   PMID:37324380   PMID:37390294   PMID:37419903   PMID:37551717   PMID:37605939   PMID:37611093   PMID:37761995   PMID:37823339  
PMID:37856473   PMID:37895315  


Genomics

Comparative Map Data
Sox17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914,561,154 - 4,567,624 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14,561,154 - 4,567,577 (-)EnsemblGRCm39 Ensembl
GRCm3814,490,928 - 4,497,426 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14,490,931 - 4,497,354 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714,481,009 - 4,486,494 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614,481,009 - 4,486,494 (-)NCBIMGSCv36mm8
Celera14,507,797 - 4,513,282 (-)NCBICelera
Cytogenetic Map1A1NCBI
cM Map11.65NCBI
SOX17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38854,457,935 - 54,460,892 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl854,457,935 - 54,460,892 (+)EnsemblGRCh38hg38GRCh38
GRCh37855,370,495 - 55,373,452 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36855,533,048 - 55,536,009 (+)NCBINCBI36Build 36hg18NCBI36
Build 34855,533,047 - 55,535,484NCBI
Celera851,361,039 - 51,364,000 (+)NCBICelera
Cytogenetic Map8q11.23NCBI
HuRef850,838,617 - 50,841,578 (+)NCBIHuRef
CHM1_1855,422,260 - 55,425,221 (+)NCBICHM1_1
T2T-CHM13v2.0854,835,189 - 54,838,146 (+)NCBIT2T-CHM13v2.0
Sox17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2515,016,660 - 15,022,228 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl515,016,731 - 15,022,228 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx517,215,894 - 17,221,391 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0518,819,700 - 18,825,180 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0518,550,534 - 18,556,035 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0514,890,318 - 14,895,907 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl514,890,408 - 14,895,907 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0519,675,563 - 19,681,084 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4515,241,405 - 15,246,904 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1515,244,440 - 15,246,899 (+)NCBI
Celera514,398,084 - 14,403,591 (+)NCBICelera
Cytogenetic Map5q12NCBI
Sox17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545413,689,403 - 13,690,019 (+)NCBIChiLan1.0ChiLan1.0
SOX17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1845,819,721 - 45,822,171 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0850,883,088 - 50,885,542 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1848,257,287 - 48,259,808 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl848,257,287 - 48,259,808 (+)Ensemblpanpan1.1panPan2
SOX17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1295,979,092 - 5,981,504 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl295,979,261 - 5,981,124 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha296,289,199 - 6,291,617 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0296,057,575 - 6,059,968 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl296,057,528 - 6,059,963 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1295,992,409 - 5,994,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0296,198,380 - 6,200,809 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0296,377,256 - 6,379,697 (+)NCBIUU_Cfam_GSD_1.0
Sox17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530373,534,065 - 73,536,600 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364961,248,577 - 1,251,430 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364961,248,582 - 1,251,406 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOX17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl476,854,150 - 76,857,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1476,854,218 - 76,857,143 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2483,968,236 - 83,971,155 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SOX17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1850,523,816 - 50,527,360 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl850,524,893 - 50,527,847 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603991,335,953 - 91,338,947 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sox17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247351,276,302 - 1,279,181 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247351,276,382 - 1,278,584 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sox17
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:312
Count of miRNA genes:208
Interacting mature miRNAs:237
Transcripts:ENSMUST00000027035, ENSMUST00000116652
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412226Alpq4_malcohol preference QTL 4 (mouse)Not determined1122976684Mouse
1301891Alcp25_malcohol preference locus 25 (mouse)Not determined1125203185Mouse
1300834Cia20_mcollagen induced arthritis 20 (mouse)Not determined1125203185Mouse
1301482Morph1_mmorphine antinociception 1 (mouse)Not determined1130367747Mouse
1301275Sle10_msystematic lupus erythematosus susceptibility 10 (mouse)Not determined1288219436882352Mouse
1301370Adip1_madiposity 1 (mouse)Not determined1288219436882352Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
15092044Wtgrme1_mweek ten growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092046Wngrme1_mweek nine growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092048Wsigrme1_mweek six growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092050Wsegrme1_mweek seven growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092051Wegrme1_mweek eight growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092055Lgrme1_mlate growth rate, maternal effect 1 (mouse)1328014237782236Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301471Obq2_mobesity QTL 2 (mouse)Not determined1394162037941887Mouse

Markers in Region
Sox17  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3814,492,354 - 4,493,273UniSTSGRCm38
MGSCv3714,482,435 - 4,483,354UniSTSGRCm37
Celera14,509,223 - 4,510,142UniSTS
Cytogenetic Map1A1UniSTS
cM Map17.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001289464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC129937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D49473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D49474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L29085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000027035   ⟹   ENSMUSP00000027035
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14,561,154 - 4,566,636 (-)Ensembl
GRCm38.p6 Ensembl14,490,931 - 4,496,413 (-)Ensembl
RefSeq Acc Id: ENSMUST00000116652   ⟹   ENSMUSP00000112351
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14,561,936 - 4,566,586 (-)Ensembl
GRCm38.p6 Ensembl14,491,713 - 4,496,363 (-)Ensembl
RefSeq Acc Id: ENSMUST00000191647   ⟹   ENSMUSP00000142204
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14,562,681 - 4,566,553 (-)Ensembl
GRCm38.p6 Ensembl14,492,458 - 4,496,330 (-)Ensembl
RefSeq Acc Id: ENSMUST00000191939   ⟹   ENSMUSP00000142154
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14,562,688 - 4,563,958 (-)Ensembl
GRCm38.p6 Ensembl14,492,465 - 4,493,735 (-)Ensembl
RefSeq Acc Id: ENSMUST00000192505
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14,562,680 - 4,563,827 (-)Ensembl
GRCm38.p6 Ensembl14,492,457 - 4,493,604 (-)Ensembl
RefSeq Acc Id: ENSMUST00000192650   ⟹   ENSMUSP00000142116
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14,561,613 - 4,567,577 (-)Ensembl
GRCm38.p6 Ensembl14,491,390 - 4,497,354 (-)Ensembl
RefSeq Acc Id: ENSMUST00000192913   ⟹   ENSMUSP00000141674
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14,562,690 - 4,566,619 (-)Ensembl
GRCm38.p6 Ensembl14,492,467 - 4,496,396 (-)Ensembl
RefSeq Acc Id: ENSMUST00000195555   ⟹   ENSMUSP00000141894
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14,561,473 - 4,566,980 (-)Ensembl
GRCm38.p6 Ensembl14,491,250 - 4,496,757 (-)Ensembl
RefSeq Acc Id: NM_001289464   ⟹   NP_001276393
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,566,664 (-)NCBI
GRCm3814,490,928 - 4,497,354 (-)NCBI
Celera14,507,797 - 4,514,223 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001289465   ⟹   NP_001276394
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,566,664 (-)NCBI
GRCm3814,490,928 - 4,497,354 (-)NCBI
Celera14,507,797 - 4,514,223 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001289466   ⟹   NP_001276395
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,566,664 (-)NCBI
GRCm3814,490,928 - 4,497,354 (-)NCBI
Celera14,507,797 - 4,514,223 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001289467   ⟹   NP_001276396
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,566,664 (-)NCBI
GRCm3814,490,928 - 4,497,354 (-)NCBI
Celera14,507,797 - 4,514,223 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001420508   ⟹   NP_001407437
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,563,831 (-)NCBI
RefSeq Acc Id: NM_001420509   ⟹   NP_001407438
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,566,664 (-)NCBI
RefSeq Acc Id: NM_011441   ⟹   NP_035571
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,566,664 (-)NCBI
GRCm3814,490,928 - 4,497,354 (-)NCBI
MGSCv3714,481,009 - 4,486,494 (-)RGD
Celera14,507,797 - 4,514,223 (-)NCBI
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030252405   ⟹   XP_030108265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,566,596 (-)NCBI
GRCm3814,490,931 - 4,496,373 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162991   ⟹   XP_036018884
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,567,624 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162992   ⟹   XP_036018885
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914,561,154 - 4,565,617 (-)NCBI
Sequence:
RefSeq Acc Id: NP_035571   ⟸   NM_011441
- Peptide Label: isoform a
- UniProtKB: Q61472 (UniProtKB/Swiss-Prot),   Q62248 (UniProtKB/Swiss-Prot),   Q61473 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001276396   ⟸   NM_001289467
- Peptide Label: isoform c
- UniProtKB: Q61473 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001276393   ⟸   NM_001289464
- Peptide Label: isoform a
- UniProtKB: Q61472 (UniProtKB/Swiss-Prot),   Q62248 (UniProtKB/Swiss-Prot),   Q61473 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001276395   ⟸   NM_001289466
- Peptide Label: isoform b
- UniProtKB: A0A0A6YXS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276394   ⟸   NM_001289465
- Peptide Label: isoform b
- UniProtKB: A0A0A6YXS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030108265   ⟸   XM_030252405
- Peptide Label: isoform X1
- UniProtKB: Q61473 (UniProtKB/Swiss-Prot),   Q61472 (UniProtKB/Swiss-Prot),   Q62248 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000027035   ⟸   ENSMUST00000027035
RefSeq Acc Id: ENSMUSP00000142154   ⟸   ENSMUST00000191939
RefSeq Acc Id: ENSMUSP00000142204   ⟸   ENSMUST00000191647
RefSeq Acc Id: ENSMUSP00000142116   ⟸   ENSMUST00000192650
RefSeq Acc Id: ENSMUSP00000141674   ⟸   ENSMUST00000192913
RefSeq Acc Id: ENSMUSP00000141894   ⟸   ENSMUST00000195555
RefSeq Acc Id: ENSMUSP00000112351   ⟸   ENSMUST00000116652
RefSeq Acc Id: XP_036018884   ⟸   XM_036162991
- Peptide Label: isoform X1
- UniProtKB: Q61473 (UniProtKB/Swiss-Prot),   Q61472 (UniProtKB/Swiss-Prot),   Q62248 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036018885   ⟸   XM_036162992
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001407438   ⟸   NM_001420509
- Peptide Label: isoform a
- UniProtKB: Q62248 (UniProtKB/Swiss-Prot),   Q61473 (UniProtKB/Swiss-Prot),   Q61472 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001407437   ⟸   NM_001420508
- Peptide Label: isoform a
- UniProtKB: Q62248 (UniProtKB/Swiss-Prot),   Q61473 (UniProtKB/Swiss-Prot),   Q61472 (UniProtKB/Swiss-Prot)
Protein Domains
HMG box   Sox C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61473-F1-model_v2 AlphaFold Q61473 1-419 view protein structure

Promoters
RGD ID:6818516
Promoter ID:MM_KWN:12
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:UC007AEY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3614,483,166 - 4,483,666 (-)MPROMDB
RGD ID:6818515
Promoter ID:MM_KWN:13
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Lung
Transcripts:NM_011441,   UC007AFA.1,   UC007AFB.1,   UC007AFC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3614,486,491 - 4,487,292 (-)MPROMDB
RGD ID:6873108
Promoter ID:EPDNEW_M4
Type:single initiation site
Name:Sox17_1
Description:Mus musculus SRY -box 17 , transcript variant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3814,493,608 - 4,493,668EPDNEW
RGD ID:6873110
Promoter ID:EPDNEW_M5
Type:initiation region
Name:Sox17_2
Description:Mus musculus SRY -box 17 , transcript variant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3814,497,371 - 4,497,431EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107543 AgrOrtholog
Ensembl Genes ENSMUSG00000025902 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000027035 ENTREZGENE
  ENSMUST00000027035.10 UniProtKB/Swiss-Prot
  ENSMUST00000116652 ENTREZGENE
  ENSMUST00000116652.8 UniProtKB/Swiss-Prot
  ENSMUST00000191647.2 UniProtKB/TrEMBL
  ENSMUST00000191939.2 UniProtKB/TrEMBL
  ENSMUST00000192650 ENTREZGENE
  ENSMUST00000192650.6 UniProtKB/TrEMBL
  ENSMUST00000192913.2 UniProtKB/TrEMBL
  ENSMUST00000195555 ENTREZGENE
  ENSMUST00000195555.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sox7/17/18_central UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sox_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20671 UniProtKB/Swiss-Prot
MGD MGI:107543 ENTREZGENE
NCBI Gene 20671 ENTREZGENE
PANTHER SOX TRANSCRIPTION FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR SOX-17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sox17_18_mid UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sox17 PhenoGen
PROSITE HMG_BOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOX_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HMG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YWS4_MOUSE UniProtKB/TrEMBL
  A0A0A6YXS3 ENTREZGENE, UniProtKB/TrEMBL
  A0A0A6YXV3_MOUSE UniProtKB/TrEMBL
  A0A0A6YXZ2_MOUSE UniProtKB/TrEMBL
  Q61472 ENTREZGENE
  Q61473 ENTREZGENE
  Q62248 ENTREZGENE
  Q6P9T1_MOUSE UniProtKB/TrEMBL
  SOX17_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q61472 UniProtKB/Swiss-Prot
  Q62248 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-26 Sox17  SRY (sex determining region Y)-box 17    SRY-box containing gene 17  Symbol and/or name change 5135510 APPROVED