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Gene: SOX17 (SRY-box transcription factor 17) Homo sapiens
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Symbol: SOX17
Name: SRY-box transcription factor 17
Description: Exhibits beta-catenin binding activity and transcription factor binding activity. Involved in several processes, including animal organ development; mRNA transcription by RNA polymerase II; and protein destabilization. Localizes to the nucleus and transcription factor complex. Implicated in vesicoureteral reflux.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ22252; SRY (sex determining region Y)-box 17; SRY box 17; SRY-box 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; VUR3
Orthologs:
Mus musculus (house mouse) : Sox17 (SRY (sex determining region Y)-box 17)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sox17 (SRY-box transcription factor 17)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox17 (SRY-box transcription factor 17)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX17 (SRY-box transcription factor 17)
Canis lupus familiaris (dog) : SOX17 (SRY-box transcription factor 17)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox17 (SRY-box transcription factor 17)
Sus scrofa (pig) : SOX17 (SRY-box transcription factor 17)
Chlorocebus sabaeus (green monkey) : SOX17 (SRY-box transcription factor 17)
Heterocephalus glaber (naked mole-rat) : Sox17 (SRY-box transcription factor 17)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl854,457,935 - 54,460,892 (+)Ensembl
GRCh38854,457,935 - 54,460,892 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37855,370,495 - 55,373,456 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36855,533,048 - 55,536,009 (+)NCBINCBI36hg18NCBI36
Build 34855,533,047 - 55,535,484NCBI
Celera851,361,039 - 51,364,000 (+)NCBI
Cytogenetic Map8q11.23NCBI
HuRef850,838,617 - 50,841,578 (+)NCBIHuRef
CHM1_1855,422,260 - 55,425,221 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SOX17
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313358
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.