1,1-dichloroethene decreases expression ISO RGD:1313359 6480464 vinylidene chloride results in decreased expression of SOX17 mRNA CTD PMID:26682919 1,2-dichloroethane increases expression ISO RGD:1313359 6480464 ethylene dichloride results in increased expression of SOX17 mRNA CTD PMID:28960355 1,2-dimethylhydrazine increases expression ISO RGD:1313359 6480464 1, 2-Dimethylhydrazine results in increased expression of SOX17 mRNA CTD PMID:22206623 17beta-estradiol decreases expression ISO RGD:1313359 6480464 Estradiol results in decreased expression of SOX17 mRNA CTD PMID:25210133 17beta-estradiol multiple interactions ISO RGD:1313359 6480464 ESR1 protein promotes the reaction [Estradiol results in decreased expression of SOX17 mRNA] CTD PMID:25210133 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1313359 6480464 Tetrachlorodibenzodioxin results in increased expression of SOX17 mRNA CTD PMID:19770486 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1313359 6480464 Tetrachlorodibenzodioxin affects the expression of SOX17 mRNA CTD PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1313359 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of SOX17 mRNA CTD PMID:25975270 3-methylcholanthrene multiple interactions ISO RGD:1313359 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOX17 mRNA CTD PMID:23519560 4,4'-diaminodiphenylmethane affects expression ISO RGD:1313359 6480464 4, 4'-diaminodiphenylmethane affects the expression of SOX17 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO RGD:1313359 6480464 bis4-hydroxyphenylsulfone results in increased expression of SOX17 mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide increases expression ISO RGD:1313359 6480464 Fenretinide results in increased expression of SOX17 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine decreases methylation EXP 6480464 Decitabine results in decreased methylation of SOX17 promoter CTD PMID:18413743 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of SOX17 mRNA, Decitabine results in increased expression of SOX17 protein CTD PMID:18413743 5-bromo-2'-deoxyuridine decreases localization EXP 6480464 Bromodeoxyuridine results in decreased localization of SOX17 protein CTD PMID:24154490 5-fluorouracil decreases expression ISO RGD:1313359 6480464 Fluorouracil results in decreased expression of SOX17 protein CTD PMID:21296659 5-fluorouracil decreases expression EXP 6480464 Fluorouracil results in decreased expression of SOX17 mRNA CTD PMID:24737281 5-fluorouracil decreases localization EXP 6480464 Fluorouracil results in decreased localization of SOX17 protein CTD PMID:24154490 6-aminonicotinamide decreases localization EXP 6480464 6-Aminonicotinamide results in decreased localization of SOX17 protein CTD PMID:24154490 6-propyl-2-thiouracil decreases expression ISO RGD:1305371 6480464 Propylthiouracil results in decreased expression of SOX17 mRNA CTD PMID:24780913 acetamide increases expression ISO RGD:1305371 6480464 acetamide results in increased expression of SOX17 mRNA CTD PMID:31881176 acetic acid decreases expression ISO RGD:1313359 6480464 Acetic Acid results in decreased expression of SOX17 protein CTD PMID:21296659 actinomycin D decreases localization EXP 6480464 Dactinomycin results in decreased localization of SOX17 protein CTD PMID:24154490 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of SOX17 mRNA CTD PMID:22100608 aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of SOX17 gene CTD PMID:27153756 all-trans-retinoic acid increases expression ISO RGD:1313359 6480464 Tretinoin results in increased expression of SOX17 mRNA CTD PMID:16236135 all-trans-retinoic acid affects expression EXP 6480464 Tretinoin affects the expression of SOX17 mRNA CTD PMID:31600526 all-trans-retinoic acid multiple interactions EXP 6480464 [4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in increased expression of SOX17 mRNA] CTD PMID:31711903 all-trans-retinoic acid decreases localization EXP 6480464 Tretinoin results in decreased localization of SOX17 protein CTD PMID:24154490 all-trans-retinol multiple interactions ISO RGD:1313359 6480464 [Vitamin A co-treated with INHBA protein] results in increased expression of SOX17 mRNA CTD PMID:17244017 arsenite(3-) increases methylation EXP 6480464 arsenite results in increased methylation of SOX17 promoter CTD PMID:23974009 benzo[a]pyrene decreases expression ISO RGD:1305371 6480464 Benzoapyrene results in decreased expression of SOX17 mRNA CTD PMID:21839799 benzo[a]pyrene increases methylation EXP 6480464 Benzoapyrene results in increased methylation of SOX17 3' UTR, Benzoapyrene results in increased methylation of SOX17 promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO RGD:1313359 6480464 [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in decreased expression of SOX17 mRNA CTD PMID:27858113 benzo[a]pyrene increases expression ISO RGD:1313359 6480464 Benzoapyrene results in increased expression of SOX17 mRNA CTD PMID:19770486 more ... benzo[b]fluoranthene increases expression ISO RGD:1313359 6480464 benzobfluoranthene results in increased expression of SOX17 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions ISO RGD:1313359 6480464 [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in decreased expression of SOX17 mRNA CTD PMID:27858113 Benzo[k]fluoranthene increases expression ISO RGD:1313359 6480464 benzokfluoranthene results in increased expression of SOX17 mRNA CTD PMID:26377693 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1305371 6480464 [Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of SOX17 mRNA CTD PMID:25031359 bisphenol A increases expression ISO RGD:1313359 6480464 bisphenol A results in increased expression of SOX17 mRNA CTD PMID:24090592 , PMID:30951980 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SOX17 mRNA CTD PMID:27271280 bisphenol A increases methylation ISO RGD:1305371 6480464 bisphenol A results in increased methylation of SOX17 gene CTD PMID:28505145 bisphenol A decreases expression ISO RGD:1305371 6480464 bisphenol A results in decreased expression of SOX17 mRNA CTD PMID:25181051 , PMID:30816183 bisphenol F increases expression ISO RGD:1313359 6480464 bisphenol F results in increased expression of SOX17 mRNA CTD PMID:30951980 bromochloroacetic acid decreases expression ISO RGD:1313359 6480464 bromochloroacetic acid results in decreased expression of SOX17 protein CTD PMID:21296659 buta-1,3-diene decreases expression ISO RGD:1313359 6480464 1, 3-butadiene results in decreased expression of SOX17 mRNA CTD PMID:29038090 butanal increases expression EXP 6480464 butyraldehyde results in increased expression of SOX17 mRNA CTD PMID:26079696 C60 fullerene increases expression ISO RGD:1305371 6480464 fullerene C60 results in increased expression of SOX17 mRNA CTD PMID:19167457 calciol increases expression ISO RGD:1313359 6480464 Cholecalciferol results in increased expression of SOX17 mRNA, Cholecalciferol results in increased expression of SOX17 protein CTD PMID:17170073 camptothecin increases methylation EXP 6480464 Camptothecin results in increased methylation of SOX17 gene CTD PMID:30720231 carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of SOX17 mRNA CTD PMID:25979313 carbon nanotube increases expression ISO RGD:1313359 6480464 Nanotubes more ... CTD PMID:25554681 CHIR 99021 multiple interactions EXP 6480464 4-5-benzo1 more ... CTD PMID:31711903 CHIR 99021 increases expression EXP 6480464 Chir 99021 results in increased expression of SOX17 mRNA CTD PMID:31711903 Chlorophacinone decreases localization EXP 6480464 chlorophacinone results in decreased localization of SOX17 protein CTD PMID:24154490 chloroprene decreases expression ISO RGD:1313359 6480464 Chloroprene results in decreased expression of SOX17 mRNA CTD PMID:23125180 chrysene multiple interactions ISO RGD:1313359 6480464 [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in decreased expression of SOX17 mRNA CTD PMID:27858113 columbamine decreases expression EXP 6480464 columbamine results in decreased expression of SOX17 mRNA CTD PMID:23124089 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of SOX17 mRNA CTD PMID:19371625 diethylstilbestrol decreases localization EXP 6480464 Diethylstilbestrol results in decreased localization of SOX17 protein CTD PMID:24154490 dimethyl sulfoxide decreases expression EXP 6480464 Dimethyl Sulfoxide results in decreased expression of SOX17 mRNA CTD PMID:22105179 diniconazole decreases localization EXP 6480464 diniconazole results in decreased localization of SOX17 protein CTD PMID:24154490 dinoseb decreases localization EXP 6480464 dinoseb results in decreased localization of SOX17 protein CTD PMID:24154490 diquat decreases localization EXP 6480464 Diquat results in decreased localization of SOX17 protein CTD PMID:24154490 dorsomorphin decreases localization EXP 6480464 dorsomorphin results in decreased localization of SOX17 protein CTD PMID:24154490 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of SOX17 mRNA CTD PMID:27188386 doxorubicin decreases localization EXP 6480464 Doxorubicin results in decreased localization of SOX17 protein CTD PMID:24154490 endosulfan increases expression ISO RGD:1305371 6480464 Endosulfan results in increased expression of SOX17 mRNA CTD PMID:29391264 fenvalerate increases expression ISO RGD:1305371 6480464 fenvalerate results in increased expression of SOX17 mRNA CTD PMID:30307764 fluazinam decreases localization EXP 6480464 fluazinam results in decreased localization of SOX17 protein CTD PMID:24154490 flusilazole decreases localization EXP 6480464 flusilazole results in decreased localization of SOX17 protein CTD PMID:24154490 folic acid decreases expression ISO RGD:1313359 6480464 Folic Acid results in decreased expression of SOX17 mRNA CTD PMID:25629700 gefitinib decreases localization EXP 6480464 gefitinib results in decreased localization of SOX17 protein CTD PMID:24154490 genistein multiple interactions ISO RGD:1305371 6480464 [Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of SOX17 mRNA CTD PMID:25031359 genistein decreases expression ISO RGD:1313359 6480464 Genistein results in decreased expression of SOX17 mRNA, Genistein results in decreased expression of SOX17 protein CTD PMID:32186404 hexaconazole decreases localization EXP 6480464 hexaconazole results in decreased localization of SOX17 protein CTD PMID:24154490 Indeno[1,2,3-cd]pyrene decreases expression ISO RGD:1313359 6480464 indeno1 more ... CTD PMID:26377693 isoprenaline increases expression ISO RGD:1313359 6480464 Isoproterenol results in increased expression of SOX17 mRNA CTD PMID:20003209 isotretinoin decreases localization EXP 6480464 Isotretinoin results in decreased localization of SOX17 protein CTD PMID:24154490 lipopolysaccharide increases expression ISO RGD:1313359 6480464 Lipopolysaccharides results in increased expression of SOX17 mRNA CTD PMID:10975854 maleic acid increases expression EXP 6480464 maleic acid results in increased expression of SOX17 mRNA CTD PMID:28392987 methamphetamine multiple interactions ISO RGD:1305371 6480464 [Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX17 mRNA CTD PMID:19564919 methamphetamine decreases expression ISO RGD:1305371 6480464 Methamphetamine results in decreased expression of SOX17 mRNA CTD PMID:19564919 mianserin decreases localization EXP 6480464 Mianserin results in decreased localization of SOX17 protein CTD PMID:24154490 mifepristone decreases expression ISO RGD:1305371 6480464 Mifepristone results in decreased expression of SOX17 mRNA CTD PMID:25972201 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of SOX17 mRNA CTD PMID:21527772 naphthalene increases expression ISO RGD:1313359 6480464 naphthalene results in increased expression of SOX17 protein CTD PMID:16239640 oxaliplatin multiple interactions ISO RGD:1305371 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SOX17 mRNA CTD PMID:25729387 paracetamol affects expression ISO RGD:1313359 6480464 Acetaminophen affects the expression of SOX17 mRNA CTD PMID:17562736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of SOX17 mRNA CTD PMID:22230336 paraquat increases expression ISO RGD:1313359 6480464 Paraquat results in increased expression of SOX17 mRNA CTD PMID:12595580 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1313359 6480464 perfluorooctane sulfonic acid results in decreased expression of SOX17 mRNA CTD PMID:25510869 phenobarbital affects expression ISO RGD:1313359 6480464 Phenobarbital affects the expression of SOX17 mRNA CTD PMID:23091169 phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of SOX17 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1313359 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOX17 mRNA CTD PMID:23519560 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of SOX17 mRNA CTD PMID:19371625 resveratrol decreases expression ISO RGD:1305371 6480464 resveratrol results in decreased expression of SOX17 mRNA CTD PMID:25905778 ritanserin decreases localization EXP 6480464 Ritanserin results in decreased localization of SOX17 protein CTD PMID:24154490 SB 431542 decreases localization EXP 6480464 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide results in decreased localization of SOX17 protein CTD PMID:24154490 SB 431542 multiple interactions EXP 6480464 4-5-benzo1 more ... CTD PMID:27188386 , PMID:31711903 SCH 23390 multiple interactions ISO RGD:1305371 6480464 [Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX17 mRNA CTD PMID:19564919 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of SOX17 mRNA CTD PMID:25895662 sorafenib decreases localization EXP 6480464 sorafenib results in decreased localization of SOX17 protein CTD PMID:24154490 sunitinib decreases localization EXP 6480464 sunitinib results in decreased localization of SOX17 protein CTD PMID:24154490 tetrachloroethene decreases expression ISO RGD:1313359 6480464 Tetrachloroethylene results in decreased expression of SOX17 mRNA CTD PMID:28973375 tetraphene increases expression ISO RGD:1313359 6480464 benzaanthracene results in increased expression of SOX17 mRNA CTD PMID:26377693 tetraphene multiple interactions ISO RGD:1313359 6480464 [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in decreased expression of SOX17 mRNA CTD PMID:27858113 thalidomide decreases localization EXP 6480464 Thalidomide results in decreased localization of SOX17 protein CTD PMID:24154490 titanium dioxide increases expression ISO RGD:1313359 6480464 titanium dioxide results in increased expression of SOX17 mRNA CTD PMID:23557971 toluene increases expression ISO RGD:1305371 6480464 Toluene results in increased expression of SOX17 mRNA CTD PMID:22967744 topotecan multiple interactions ISO RGD:1305371 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SOX17 mRNA CTD PMID:25729387 trichloroethene decreases methylation ISO RGD:1305371 6480464 Trichloroethylene results in decreased methylation of SOX17 gene CTD PMID:27618143 trichloroethene decreases expression ISO RGD:1313359 6480464 Trichloroethylene results in decreased expression of SOX17 mRNA CTD PMID:28013219 triclosan decreases expression EXP 6480464 Triclosan results in decreased expression of SOX17 mRNA CTD PMID:30510588 trimellitic anhydride decreases expression ISO RGD:1313359 6480464 trimellitic anhydride results in decreased expression of SOX17 mRNA CTD PMID:19042947 valproic acid decreases localization EXP 6480464 Valproic Acid results in decreased localization of SOX17 protein CTD PMID:24154490 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of SOX17 mRNA CTD PMID:25979313 vandetanib decreases localization EXP 6480464 N-4-bromo-2-fluorophenyl-6-methoxy-7-1-methylpiperidin-4-ylmethoxyquinazolin-4-amine results in decreased localization of SOX17 protein CTD PMID:24154490 vinclozolin affects expression ISO RGD:1305371 6480464 vinclozolin affects the expression of SOX17 mRNA CTD PMID:19015723 ziprasidone decreases localization EXP 6480464 ziprasidone results in decreased localization of SOX17 protein CTD PMID:24154490 zoledronic acid increases expression EXP 6480464 zoledronic acid results in increased expression of SOX17 mRNA CTD PMID:24714768