Got1 (glutamic-oxaloacetic transaminase 1, soluble) - Rat Genome Database
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Gene: Got1 (glutamic-oxaloacetic transaminase 1, soluble) Mus musculus
Analyze
Symbol: Got1
Name: glutamic-oxaloacetic transaminase 1, soluble
RGD ID: 10675
MGI Page MGI
Description: Exhibits L-aspartate:2-oxoglutarate aminotransferase activity and phosphatidylserine decarboxylase activity. Involved in several processes, including dicarboxylic acid metabolic process; fatty acid homeostasis; and glycerol biosynthetic process. Localizes to cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in amyloidosis; amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Orthologous to human GOT1 (glutamic-oxaloacetic transaminase 1); PARTICIPATES IN AGAT deficiency pathway; alkaptonuria pathway; arginine and proline metabolic pathway; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI789014; aspartate aminotransferase, cytoplasmic; cA; cAspAT; cCAT; cysteine aminotransferase, cytoplasmic; cysteine transaminase, cytoplasmic; cytosolic aspartate aminotransferase; glutamate oxaloacetate transaminase 1, soluble; Got-; Got-1; transaminase A
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391943,488,191 - 43,514,743 (-)NCBIGRCm39mm39
GRCm39 Ensembl1943,488,191 - 43,513,044 (-)Ensembl
GRCm381943,499,752 - 43,524,605 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1943,499,752 - 43,524,605 (-)EnsemblGRCm38mm10GRCm38
MGSCv371943,574,242 - 43,599,095 (-)NCBIGRCm37mm9NCBIm37
MGSCv361943,553,066 - 43,577,820 (-)NCBImm8
Celera1944,291,421 - 44,309,811 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1936.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(2,4,5-trichlorophenoxy)acetic acid  (EXP)
(Z)-3-butylidenephthalide  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrabromodibenzodioxine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
adefovir pivoxil  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
aldrin  (EXP)
ammonium chloride  (ISO)
arsenous acid  (ISO)
atorvastatin calcium  (ISO)
baicalin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
bromobenzene  (ISO)
cadmium dichloride  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chloroethene  (EXP)
chlorpyrifos  (EXP)
cidofovir anhydrous  (ISO)
ciguatoxin CTX1B  (EXP)
cis-caffeic acid  (ISO)
cisplatin  (ISO)
clobetasol  (EXP)
clofibrate  (EXP)
clotrimazole  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (EXP,ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
cypermethrin  (EXP,ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
diethyl phthalate  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
diuron  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
fenofibrate  (ISO)
fenvalerate  (ISO)
flutamide  (ISO)
formaldehyde  (ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (ISO)
glucose  (ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
ibuprofen  (ISO)
indometacin  (ISO)
iodide salt  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
iron(3+) sulfate  (ISO)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
loperamide  (ISO)
mancozeb  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
monosodium L-glutamate  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nefazodone  (ISO)
oxaloacetic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (ISO)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (ISO)
propiconazole  (EXP)
quercetin  (EXP)
ranitidine  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-allylcysteine  (EXP)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
sevoflurane  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sodium nitrate  (EXP)
streptozocin  (ISO)
sulfur dioxide  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thalidomide  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
trans-caffeic acid  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon terminus  (ISO)
cytoplasm  (ISO)
cytosol  (IBA,IDA,ISO)
lysosome  (ISO)
nucleoplasm  (ISO)

References

References - curated
1. Abd El-Latif AA, etal., Injury. 2016 Dec;47(12):2709-2717. doi: 10.1016/j.injury.2016.10.003. Epub 2016 Oct 6.
2. Begum MM, etal., Indian J Clin Biochem. 2014 Oct;29(4):452-61. doi: 10.1007/s12291-013-0393-1. Epub 2013 Oct 24.
3. Berry MN, etal., FEBS Lett. 1988 Apr 11;231(1):19-24.
4. Bouhafs L, etal., Ren Fail. 2015;37(8):1370-8. doi: 10.3109/0886022X.2015.1073543. Epub 2015 Aug 14.
5. Chen S, etal., Lab Invest. 2015 Feb;95(2):142-56. doi: 10.1038/labinvest.2014.147. Epub 2015 Jan 12.
6. Dondorf F, etal., World J Gastroenterol. 2017 Jun 21;23(23):4191-4199. doi: 10.3748/wjg.v23.i23.4191.
7. El Hidan MA, etal., Toxicon. 2016 Mar 1;111:22-30. doi: 10.1016/j.toxicon.2015.12.010. Epub 2015 Dec 22.
8. El-Gendy MMAA, etal., Appl Biochem Biotechnol. 2017 Nov;183(3):833-852. doi: 10.1007/s12010-017-2467-7. Epub 2017 Apr 7.
9. Fahmy SR, BMC Complement Altern Med. 2015 Feb 5;15:14. doi: 10.1186/s12906-015-0533-7.
10. Han Y, etal., Neurosci Lett. 2014 Mar 20;563:149-54. doi: 10.1016/j.neulet.2013.12.042. Epub 2013 Dec 25.
11. Hinkelbein J, etal., Mol Cell Biochem. 2010 Jun;339(1-2):9-21. doi: 10.1007/s11010-009-0365-1. Epub 2010 Jan 5.
12. Lahbib K and Touil S, Biomed Pharmacother. 2016 Oct;83:186-193. doi: 10.1016/j.biopha.2016.06.022. Epub 2016 Jun 28.
13. Liang Y, etal., Lab Invest. 2011 Jan;91(1):12-23. doi: 10.1038/labinvest.2010.156. Epub 2010 Aug 23.
14. Martens JC, etal., Mol Cell Biochem. 2015 Feb;400(1-2):253-63. doi: 10.1007/s11010-014-2282-1. Epub 2014 Nov 23.
15. McKenna MC, etal., Biochem Pharmacol. 2006 Feb 14;71(4):399-407. Epub 2005 Dec 20.
16. MGD and Homologene mouse data transfer
17. MGD data from the GO Consortium
18. Pipeline to import KEGG annotations from KEGG into RGD
19. Pipeline to import SMPDB annotations from SMPDB into RGD
20. PĂ©rez-Mato M, etal., Cell Death Dis. 2014 Jan 9;5:e992. doi: 10.1038/cddis.2013.507.
21. RGD automated import pipeline for gene-chemical interactions
22. Rink C, etal., Antioxid Redox Signal. 2011 May 15;14(10):1777-85. doi: 10.1089/ars.2011.3930. Epub 2011 Mar 28.
23. Rink C, etal., J Cereb Blood Flow Metab. 2010 Jul;30(7):1275-87. doi: 10.1038/jcbfm.2010.7. Epub 2010 Feb 10.
24. Ruban A, etal., Neurodegener Dis. 2015;15(4):233-42. doi: 10.1159/000382034. Epub 2015 Jun 23.
25. Samout N, etal., Biomed Pharmacother. 2016 Oct;83:1233-1238. doi: 10.1016/j.biopha.2016.08.038. Epub 2016 Aug 23.
26. Son J, etal., Nature. 2013 Apr 4;496(7443):101-5. doi: 10.1038/nature12040. Epub 2013 Mar 27.
27. Sun Y, etal., Lab Invest. 2010 Jan;90(1):68-82. Epub 2009 Oct 12.
28. Vyshtakalyuk AB, etal., Int J Risk Saf Med. 2015;27 Suppl 1:S78-9. doi: 10.3233/JRS-150698.
29. Yasue M, etal., Cytogenet Cell Genet 1991;57(2-3):142-8
30. Ying W Antioxid Redox Signal. 2008 Feb;10(2):179-206.
31. Zhang D, etal., Neuropharmacology. 2017 Jul 15;121:231-246. doi: 10.1016/j.neuropharm.2017.03.036. Epub 2017 Apr 5.
32. Zlotnik A, etal., Exp Neurol. 2007 Jan;203(1):213-20. doi: 10.1016/j.expneurol.2006.08.021. Epub 2006 Oct 2.
Additional References at PubMed
PMID:1840559   PMID:2571572   PMID:2787792   PMID:3242498   PMID:3379636   PMID:3782150   PMID:4193185   PMID:7444718   PMID:7749225   PMID:7835908   PMID:7846052   PMID:7873877  
PMID:8390965   PMID:8666395   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466305   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12904583  
PMID:14610273   PMID:14681479   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16182522   PMID:17248564   PMID:17545671   PMID:17967808   PMID:18799693   PMID:19423573  
PMID:21267068   PMID:21873635   PMID:24154525   PMID:25446530   PMID:26336360   PMID:27160897   PMID:27760309   PMID:30562941   PMID:31647966   PMID:32325033  


Genomics

Comparative Map Data
Got1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391943,488,191 - 43,514,743 (-)NCBIGRCm39mm39
GRCm39 Ensembl1943,488,191 - 43,513,044 (-)Ensembl
GRCm381943,499,752 - 43,524,605 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1943,499,752 - 43,524,605 (-)EnsemblGRCm38mm10GRCm38
MGSCv371943,574,242 - 43,599,095 (-)NCBIGRCm37mm9NCBIm37
MGSCv361943,553,066 - 43,577,820 (-)NCBImm8
Celera1944,291,421 - 44,309,811 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1936.67NCBI
GOT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1099,396,870 - 99,430,624 (-)EnsemblGRCh38hg38GRCh38
GRCh381099,396,870 - 99,430,624 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710101,156,627 - 101,190,381 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610101,146,618 - 101,180,336 (-)NCBINCBI36hg18NCBI36
Build 3410101,146,617 - 101,180,336NCBI
Celera1094,893,454 - 94,927,360 (-)NCBI
Cytogenetic Map10q24.2NCBI
HuRef1094,783,264 - 94,817,025 (-)NCBIHuRef
CHM1_110101,438,925 - 101,472,830 (-)NCBICHM1_1
Got1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21242,357,293 - 242,381,535 (-)NCBI
Rnor_6.0 Ensembl1263,246,248 - 263,269,762 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01263,246,248 - 263,269,762 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01270,691,424 - 270,714,958 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41247,324,285 - 247,347,553 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1238,178,819 - 238,202,121 (-)NCBICelera
RH 3.4 Map1 RGD
Cytogenetic Map1q54NCBI
Got1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555075,346,838 - 5,370,072 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555075,346,937 - 5,370,072 (-)NCBIChiLan1.0ChiLan1.0
GOT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11099,506,205 - 99,540,178 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1099,506,205 - 99,540,178 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01096,012,345 - 96,046,266 (-)NCBIMhudiblu_PPA_v0panPan3
GOT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12812,352,658 - 12,377,960 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2812,352,659 - 12,414,579 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2812,536,462 - 12,561,764 (-)NCBI
ROS_Cfam_1.02812,820,566 - 12,845,869 (-)NCBI
UMICH_Zoey_3.12812,367,262 - 12,392,563 (-)NCBI
UNSW_CanFamBas_1.02812,398,502 - 12,423,851 (-)NCBI
UU_Cfam_GSD_1.02812,539,850 - 12,565,179 (-)NCBI
Got1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2NW_02440721334,578,280 - 34,601,317 (+)NCBI
SpeTri2.0NW_004936636617,376 - 640,424 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GOT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14110,608,430 - 110,635,874 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114110,608,422 - 110,635,825 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214120,054,006 - 120,080,894 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GOT1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1992,463,017 - 92,489,227 (-)NCBI
ChlSab1.1 Ensembl992,462,782 - 92,488,310 (-)Ensembl
Got1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473711,114,818 - 11,153,209 (-)NCBI

Position Markers
AI789014  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381943,500,003 - 43,500,143UniSTSGRCm38
MGSCv371943,574,493 - 43,574,633UniSTSGRCm37
Celera1944,291,672 - 44,291,814UniSTS
Cytogenetic Map19C3UniSTS
cM Map1937.0UniSTS
Whitehead/MRC_RH19409.45UniSTS
Whitehead/MRC_RH19432.15UniSTS
Whitehead/MRC_RH19430.74UniSTS
Got1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371943,579,267 - 43,579,412UniSTSGRCm37
Celera1944,296,445 - 44,296,590UniSTS
Cytogenetic Map19C3UniSTS
cM Map1937.0UniSTS
GOT1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381943,504,777 - 43,504,922UniSTSGRCm38
MGSCv371943,579,267 - 43,579,412UniSTSGRCm37
Celera1944,296,445 - 44,296,590UniSTS
Cytogenetic Map19C3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19981005343810202Mouse
14928311Manh85_mmandible shape 85 (mouse)191193738945937389Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191494561648945738Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191593520749935319Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191593520749935319Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191831776252317981Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191831776252317981Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192025691554257062Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192025691554257062Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192139025755390480Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192233596253923073Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192500000059000000Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192543847859438566Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192739715561397266Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2815190961431566Mouse
4141562Pas3b_mpulmonary adenoma susceptibility 3b (mouse)Not determined2977296261431566Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193015278561431566Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193015279261431566Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193015279261431566Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193090944161431566Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193300371961431566Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193396351461431566Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3460834861431566Mouse
1301479Sluc1_msusceptibility to lung cancer 1 (mouse)Not determined193603954446773082Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193676416661431566Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193789455061431566Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193838761861431566Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193919563261431566Mouse
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193960763461431566Mouse
1300585Pgia12_mproteoglycan induced arthritis 12 (mouse)Not determined194259842761431566Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1567
Count of miRNA genes:651
Interacting mature miRNAs:801
Transcripts:ENSMUST00000026196, ENSMUST00000124954, ENSMUST00000132504, ENSMUST00000133325
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004940117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC138790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV574373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY441762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK334037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000026196   ⟹   ENSMUSP00000026196
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1943,499,752 - 43,524,605 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124954
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1943,512,254 - 43,524,485 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132504
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1943,500,315 - 43,504,796 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133325   ⟹   ENSMUSP00000117986
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1943,500,021 - 43,515,865 (-)Ensembl
RefSeq Acc Id: NM_010324   ⟹   NP_034454
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391943,488,191 - 43,513,044 (-)NCBI
GRCm381943,499,752 - 43,524,605 (-)ENTREZGENE
MGSCv371943,574,242 - 43,599,095 (-)RGD
Celera1944,291,421 - 44,309,811 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_004940117
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391943,488,191 - 43,514,743 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_034454   ⟸   NM_010324
- UniProtKB: P05201 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000026196   ⟸   ENSMUST00000026196
RefSeq Acc Id: ENSMUSP00000117986   ⟸   ENSMUST00000133325
Protein Domains
Aminotran_1_2

Promoters
RGD ID:13679544
Promoter ID:EPDNEW_M23920
Type:initiation region
Name:Got1_1
Description:Mus musculus glutamic-oxaloacetic transaminase 1, soluble , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381943,524,530 - 43,524,590EPDNEW
RGD ID:6847560
Promoter ID:MM_ACW:26867
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Liver
Transcripts:GOT1.ESEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361943,574,359 - 43,574,859 (-)MPROMDB
RGD ID:6830102
Promoter ID:MM_KWN:27120
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:UC008HOJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361943,581,211 - 43,581,711 (-)MPROMDB
RGD ID:6830099
Promoter ID:MM_KWN:27121
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver
Transcripts:OTTMUST00000057632
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361943,590,909 - 43,591,409 (-)MPROMDB
RGD ID:6830100
Promoter ID:MM_KWN:27122
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000057631,   OTTMUST00000057633,   UC008HOI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361943,598,899 - 43,599,399 (-)MPROMDB
RGD ID:6849754
Promoter ID:EP32003
Type:multiple initiation site
Name:MM_AATC
Description:Aspartate aminotransferase cytosolic (Glutamate oxaloacetatetransaminase-1), GOT1 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 186; Mammalian cytosolic aspartate aminotransferase
Tissues & Cell Lines:housekeeping gene
Experiment Methods:Nuclease protection with homologous sequence ladder
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv371943,599,024 - 43,599,084EPD
MGSCv361943,599,024 - 43,599,084EPD

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95791 AgrOrtholog
Ensembl Genes ENSMUSG00000025190 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000026196 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000117986 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026196 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000133325 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/Swiss-Prot
InterPro Aminotransferase_I/II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Asp_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NHTrfase_class1_PyrdxlP-BS UniProtKB/Swiss-Prot
  PyrdxlP-dep_Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_dom1 UniProtKB/Swiss-Prot
  PyrdxlP-dep_Trfase_major UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14718 UniProtKB/Swiss-Prot
MGD MGI:95791 ENTREZGENE
NCBI Gene 14718 ENTREZGENE
PANTHER PTHR11879 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aminotran_1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Got1 PhenoGen
PRINTS TRANSAMINASE UniProtKB/Swiss-Prot
PROSITE AA_TRANSFER_CLASS_1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AATC_MOUSE UniProtKB/Swiss-Prot
  F7ALS6_MOUSE UniProtKB/TrEMBL
  P05201 ENTREZGENE
UniProt Secondary Q3UJH8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-09-30 Got1  glutamic-oxaloacetic transaminase 1, soluble    glutamate oxaloacetate transaminase 1, soluble  Symbol and/or name change 5135510 APPROVED