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Gene: Got1 (glutamic-oxaloacetic transaminase 1, soluble) Mus musculus
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Symbol: Got1
Name: glutamic-oxaloacetic transaminase 1, soluble
Description: Exhibits L-aspartate:2-oxoglutarate aminotransferase activity and phosphatidylserine decarboxylase activity. Involved in several processes, including dicarboxylic acid metabolic process; fatty acid homeostasis; and glycerol biosynthetic process. Localizes to the cytosol. Human ortholog(s) of this gene implicated in amyloidosis; amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human GOT1 (glutamic-oxaloacetic transaminase 1); PARTICIPATES IN AGAT deficiency pathway; alkaptonuria pathway; arginine and proline metabolic pathway; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI789014; aspartate aminotransferase, cytoplasmic; cAspAT; cCAT; cysteine aminotransferase, cytoplasmic; cysteine transaminase, cytoplasmic; cytosolic aspartate aminotransferase; glutamate oxaloacetate transaminase 1, soluble; Got-1; transaminase A
Orthologs:
Homo sapiens (human) : GOT1 (glutamic-oxaloacetic transaminase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Got1 (glutamic-oxaloacetic transaminase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Got1 (glutamic-oxaloacetic transaminase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GOT1 (glutamic-oxaloacetic transaminase 1)
Canis lupus familiaris (dog) : GOT1 (glutamic-oxaloacetic transaminase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Got1 (glutamic-oxaloacetic transaminase 1)
Sus scrofa (pig) : GOT1 (glutamic-oxaloacetic transaminase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1943,499,752 - 43,524,605 (-)Ensembl
GRCm381943,499,752 - 43,524,605 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371943,574,242 - 43,599,095 (-)NCBIGRCm37mm9NCBIm37
MGSCv361943,553,066 - 43,577,820 (-)NCBImm8
Celera1944,291,421 - 44,309,811 (-)NCBICelera
Cytogenetic Map19 C3NCBI
cM Map1936.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on Got1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10675
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.