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Gene: Got1 (glutamic-oxaloacetic transaminase 1, soluble) Mus musculus
Symbol: Got1
Name: glutamic-oxaloacetic transaminase 1, soluble
Description: Exhibits L-aspartate:2-oxoglutarate aminotransferase activity and phosphatidylserine decarboxylase activity. Involved in several processes, including dicarboxylic acid metabolic process; fatty acid homeostasis; and glycerol biosynthetic process. Localizes to the cytosol. Human ortholog(s) of this gene implicated in amyloidosis; amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human GOT1 (glutamic-oxaloacetic transaminase 1); PARTICIPATES IN AGAT deficiency pathway; alkaptonuria pathway; arginine and proline metabolic pathway; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI789014; aspartate aminotransferase, cytoplasmic; cAspAT; cCAT; cysteine aminotransferase, cytoplasmic; cysteine transaminase, cytoplasmic; cytosolic aspartate aminotransferase; glutamate oxaloacetate transaminase 1, soluble; Got-1; transaminase A
Homo sapiens (human) : GOT1 (glutamic-oxaloacetic transaminase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Got1 (glutamic-oxaloacetic transaminase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Got1 (glutamic-oxaloacetic transaminase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GOT1 (glutamic-oxaloacetic transaminase 1)
Canis lupus familiaris (dog) : GOT1 (glutamic-oxaloacetic transaminase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Got1 (glutamic-oxaloacetic transaminase 1)
Sus scrofa (pig) : GOT1 (glutamic-oxaloacetic transaminase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1943,499,752 - 43,524,605 (-)Ensembl
GRCm381943,499,752 - 43,524,605 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371943,574,242 - 43,599,095 (-)NCBIGRCm37mm9NCBIm37
MGSCv361943,553,066 - 43,577,820 (-)NCBImm8
Celera1944,291,421 - 44,309,811 (-)NCBICelera
Cytogenetic Map19 C3NCBI
cM Map1936.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Got1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10675
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.