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Gene: Col4a1 (collagen, type IV, alpha 1) Mus musculus
Symbol: Col4a1
Name: collagen, type IV, alpha 1
Description: Predicted to have extracellular matrix structural constituent conferring tensile strength and platelet-derived growth factor binding activity. Involved in cellular response to amino acid stimulus; collagen-activated tyrosine kinase receptor signaling pathway; and neuromuscular junction development. Localizes to the collagen type IV trimer. Used to study COL4A1-related familial vascular leukoencephalopathy; Walker-Warburg syndrome; kidney disease; and porencephaly. Human ortholog(s) of this gene implicated in COL4A1-related familial vascular leukoencephalopathy and myocardial infarction. Is expressed in several structures, including alimentary system; brain; egg cylinder; genitourinary system; and sensory organ. Orthologous to human COL4A1 (collagen type IV alpha 1 chain).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-1 type IV collagen; alpha1(IV) collagen; Bru; Col4a-1; collagen alpha-1(IV) chain; Del(8)44H; Del(8)Bru44H; procollagen, type IV, alpha 1; Raw; retinal anterior wiring; Svc
Homo sapiens (human) : COL4A1 (collagen type IV alpha 1 chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Col4a1 (collagen type IV alpha 1 chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col4a1 (collagen type IV alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL4A1 (collagen type IV alpha 1 chain)
Canis lupus familiaris (dog) : COL4A1 (collagen type IV alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col4a1 (collagen type IV alpha 1 chain)
Sus scrofa (pig) : COL4A1 (collagen type IV alpha 1 chain)
Chlorocebus sabaeus (African green monkey) : COL4A1 (collagen type IV alpha 1 chain)
Heterocephalus glaber (naked mole-rat) : Col4a1 (collagen type IV alpha 1 chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl811,198,423 - 11,312,826 (-)Ensembl
GRCm38811,198,423 - 11,312,889 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37811,198,423 - 11,312,826 (-)NCBIGRCm37mm9NCBIm37
MGSCv36811,198,403 - 11,312,702 (-)NCBImm8
Celera811,372,057 - 11,487,438 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Col4a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316171
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.