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Gene: Tfeb (transcription factor EB) Mus musculus
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Symbol: Tfeb
Name: transcription factor EB
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in several processes, including defense response to Gram-negative bacterium; embryonic placenta development; and regulation of defense response to bacterium, incompatible interaction. Localizes to the cytoplasm; nucleus; and transcription factor complex. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; genitourinary system; and gut gland. Orthologous to human TFEB (transcription factor EB); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5-triiodo-L-thyronine; arachidonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHe35; Tcfeb
Orthologs:
Homo sapiens (human) : TFEB (transcription factor EB)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfeb (transcription factor EB)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfeb (transcription factor EB)
Pan paniscus (bonobo/pygmy chimpanzee) : TFEB (transcription factor EB)
Canis lupus familiaris (dog) : TFEB (transcription factor EB)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfeb (transcription factor EB)
Sus scrofa (pig) : TFEB (transcription factor EB)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381747,737,037 - 47,792,416 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371747,873,986 - 47,929,365 (+)NCBIGRCm37mm9NCBIm37
MGSCv361747,248,935 - 47,255,607 (+)NCBImm8
Celera1751,174,084 - 51,229,512 (+)NCBICelera
Cytogenetic Map17 CNCBI
cM Map1723.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Tfeb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319998
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.