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Gene: Sftpc (surfactant associated protein C) Mus musculus
Symbol: Sftpc
Name: surfactant associated protein C
Description: Predicted to have protein homodimerization activity. Predicted to be involved in protein homooligomerization. Localizes to the cytoplasm and extracellular region. Used to study desquamative interstitial pneumonia. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); and respiratory syncytial virus infectious disease. Is expressed in lung and main bronchus epithelium. Orthologous to human SFTPC (surfactant protein C); INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bricd6; pro-SpC; pulmonary surfactant-associated protein C; pulmonary surfactant-associated proteolipid SPL(Val); Sftp-2; Sftp2; SP-C; SP5; SPC
Homo sapiens (human) : SFTPC (surfactant protein C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sftpc (surfactant protein C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sftpc (surfactant protein C)
Pan paniscus (bonobo/pygmy chimpanzee) : SFTPC (surfactant protein C)
Canis lupus familiaris (dog) : SFTPC (surfactant protein C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sftpc (surfactant protein C)
Sus scrofa (pig) : SFTPC (surfactant protein C)
Chlorocebus sabaeus (green monkey) : SFTPC (surfactant protein C)
Heterocephalus glaber (naked mole-rat) : Sftpc (surfactant protein C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1470,520,949 - 70,524,081 (-)Ensembl
GRCm381470,520,941 - 70,524,081 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371470,920,748 - 70,923,888 (-)NCBIGRCm37mm9NCBIm37
MGSCv361469,256,020 - 69,259,150 (-)NCBImm8
Celera1468,062,491 - 68,065,631 (-)NCBICelera
Cytogenetic Map14 D2NCBI
cM Map1436.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sftpc
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733829
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.