Dsp (desmoplakin) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dsp (desmoplakin) Mus musculus
Analyze
Symbol: Dsp
Name: desmoplakin
RGD ID: 1620673
MGI Page MGI
Description: Predicted to enable protein kinase C binding activity; scaffold protein binding activity; and structural molecule activity. Involved in intermediate filament organization; protein localization to cell-cell junction; and ventricular compact myocardium morphogenesis. Acts upstream of or within several processes, including cell-cell junction organization; intermediate filament cytoskeleton organization; and skin development. Located in basolateral plasma membrane; desmosome; and intercalated disc. Colocalizes with intermediate filament. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; heart; and sensory organ. Used to study Carvajal syndrome and arrhythmogenic right ventricular dysplasia 8. Human ortholog(s) of this gene implicated in Carvajal syndrome; arrhythmogenic right ventricular cardiomyopathy; arrhythmogenic right ventricular dysplasia 8; and dilated cardiomyopathy. Orthologous to human DSP (desmoplakin); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2300002E22Rik; 5730453H04Rik; AA407887; AA407888; AW109828; D; desmoplakin I/II; desmosomal cytoskeletal connector molecule; DP; r; RIKEN cDNA 5730453H04 gene; rul
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391338,335,270 - 38,382,553 (+)NCBIGRCm39mm39
GRCm39 Ensembl1338,335,270 - 38,382,553 (+)Ensembl
GRCm381338,151,294 - 38,198,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1338,151,294 - 38,198,577 (+)EnsemblGRCm38mm10GRCm38
MGSCv371338,243,163 - 38,290,446 (+)NCBIGRCm37mm9NCBIm37
MGSCv361338,158,760 - 38,206,043 (+)NCBImm8
Celera1339,265,897 - 39,313,259 (+)NCBICelera
Cytogenetic Map13A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
arrhythmogenic right ventricular cardiomyopathy  (ISO)
arrhythmogenic right ventricular dysplasia 1  (ISO)
arrhythmogenic right ventricular dysplasia 8  (IEA,ISO)
arrhythmogenic right ventricular dysplasia 9  (ISO)
Brugada syndrome  (ISO)
cardiac arrest  (ISO)
Cardiac Arrhythmias  (ISO)
cardiomyopathy  (ISO)
Carvajal syndrome  (IEA,ISO)
catecholaminergic polymorphic ventricular tachycardia 1  (ISO)
chronic obstructive pulmonary disease  (ISO)
Developmental Disabilities  (ISO)
dilated cardiomyopathy  (ISO)
dilated cardiomyopathy 1A  (ISO)
dilated cardiomyopathy 1B  (ISO)
dilated cardiomyopathy 1H  (ISO)
dilated cardiomyopathy 1S  (ISO)
Dilated Cardiomyopathy with Left Ventricular Noncompaction  (ISO)
Dilated Cardiomyopathy with Woolly Hair, Keratoderma, and Tooth Agenesis  (ISO)
Ectodermal Dysplasia-Skin Fragility Syndrome  (ISO)
Epidermolysis Bullosa, Lethal Acantholytic  (ISO)
familial hypertrophic cardiomyopathy  (ISO)
Heart Block  (ISO)
hemiplegia  (ISO)
hypertrophic cardiomyopathy  (ISO)
hypertrophic cardiomyopathy 1  (ISO)
idiopathic pulmonary fibrosis  (ISO)
Keratosis Palmoplantaris Striata 2  (ISO)
Left Ventricular Hypertrophy  (ISO)
left ventricular noncompaction  (ISO)
long QT syndrome  (ISO)
long QT syndrome 1  (ISO)
Marfanoid Mental Retardation Syndrome, Autosomal  (ISO)
migraine  (ISO)
Paroxysmal Ventricular Fibrillation  (ISO)
progressive familial heart block  (ISO)
pulmonary fibrosis  (ISO)
restrictive cardiomyopathy  (ISO)
Skin Fragility-Woolly Hair Syndrome  (ISO)
subvalvular aortic stenosis  (ISO)
Sudden Cardiac Death  (ISO)
Sudden Death  (ISO)
Sudden Unexpected Nocturnal Death Syndrome  (ISO)
Syncope  (ISO)
systolic heart failure  (ISO)
Ventricular Fibrillation  (ISO)
Ventricular Fibrillation, Paroxysmal Familial, 1  (ISO)
Ventricular Tachycardia  (ISO)
Wolff-Parkinson-White syndrome  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
amphetamine  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
cocaine  (ISO)
copper(II) sulfate  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP,ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dihydroartemisinin  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
folic acid  (EXP)
glafenine  (ISO)
indometacin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methylmercury chloride  (ISO)
monosodium L-glutamate  (EXP)
N-acetyl-L-cysteine  (ISO)
nitrofen  (ISO)
Nonylphenol  (ISO)
okadaic acid  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP)
propiconazole  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sulforaphane  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
topotecan  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cell adhesion  (IAGP)
abnormal corneocyte envelope morphology  (IAGP)
abnormal ectoderm development  (IAGP)
abnormal egg cylinder morphology  (IAGP)
abnormal embryo turning  (IEA)
abnormal embryonic tissue morphology  (IAGP)
abnormal endoderm development  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal epidermis stratum spinosum morphology  (IAGP)
abnormal hair medulla  (IAGP)
abnormal hair medullary septa cells  (IAGP)
abnormal hair shaft morphology  (IAGP)
abnormal hair texture  (IAGP)
abnormal heart apex morphology  (IAGP)
abnormal heart echocardiography feature  (IAGP)
abnormal heart electrocardiography waveform feature  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal heart morphology  (IAGP)
abnormal impulse conducting system conduction  (IAGP)
abnormal intercalated disk morphology  (IAGP)
abnormal lymph node morphology  (IEA)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal neural tube closure  (IEA)
abnormal neural tube morphology  (IEA)
abnormal peripheral nervous system regeneration  (IAGP)
abnormal pharyngeal arch morphology  (IEA)
abnormal R wave  (IAGP)
abnormal sciatic nerve morphology  (IAGP)
abnormal subendocardium layer morphology  (IAGP)
abnormal T wave  (IAGP)
abnormal vibrissa follicle morphology  (IAGP)
abnormal Z line morphology  (IAGP)
acanthosis  (IAGP)
bundle branch block  (IAGP)
cardiac fibrosis  (IAGP)
decreased bone mineral density  (IEA)
decreased embryo size  (IAGP)
decreased heart rate  (IAGP)
decreased nerve conduction velocity  (IAGP)
decreased ventricle muscle contractility  (IAGP)
delayed axon extension  (IAGP)
dermal-epidermal separation  (IAGP)
dilated heart ventricle  (IAGP)
disheveled coat  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
enlarged heart  (IAGP)
enlarged heart atrium  (IAGP)
enlarged lymph nodes  (IEA)
impaired ability to fire action potentials  (IAGP)
increased apoptosis  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
irregular heartbeat  (IAGP)
oral mucosa blisters  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IEA)
prolonged QRS complex duration  (IAGP)
prolonged RR interval  (IAGP)
ruffled hair  (IAGP)
sparse hair  (IAGP)
ventricular cardiomyopathy  (IAGP)
ventricular premature beat  (IAGP)
References

Additional References at PubMed
PMID:7493021   PMID:8858175   PMID:8950514   PMID:9412476   PMID:9847250   PMID:9864371   PMID:10349636   PMID:10597135   PMID:11013209   PMID:11042159   PMID:11076861   PMID:11217851  
PMID:11222147   PMID:11239416   PMID:11566879   PMID:11781569   PMID:12466851   PMID:12477932   PMID:12724416   PMID:12951053   PMID:12975353   PMID:14627958   PMID:14651853   PMID:14673151  
PMID:15190119   PMID:15234001   PMID:15346771   PMID:15479741   PMID:15797384   PMID:16086310   PMID:16141072   PMID:16141073   PMID:16303847   PMID:16337936   PMID:16418220   PMID:16543498  
PMID:16602821   PMID:16823493   PMID:16917092   PMID:17095659   PMID:17227889   PMID:17409114   PMID:17535849   PMID:17576135   PMID:17766470   PMID:18166659   PMID:18292208   PMID:18496566  
PMID:18694874   PMID:18703497   PMID:18809908   PMID:19001636   PMID:19359597   PMID:19723622   PMID:19841136   PMID:20093627   PMID:20424327   PMID:20862307   PMID:21038445   PMID:21267068  
PMID:21285247   PMID:21377456   PMID:21565611   PMID:21659647   PMID:21677750   PMID:21844209   PMID:21873635   PMID:22238362   PMID:22240500   PMID:22513779   PMID:22588081   PMID:22673621  
PMID:23108156   PMID:23132931   PMID:23877755   PMID:24108106   PMID:24161570   PMID:24276085   PMID:24457600   PMID:24952961   PMID:25133425   PMID:25139745   PMID:25496840   PMID:25617501  
PMID:25659760   PMID:25733715   PMID:25917818   PMID:26403541   PMID:26514267   PMID:26545710   PMID:26644517   PMID:26763459   PMID:27097650   PMID:27121621   PMID:27519653   PMID:27551807  
PMID:27766308   PMID:27892606   PMID:28507225   PMID:28634551   PMID:28760667   PMID:28793255   PMID:28827800   PMID:29018034   PMID:29183906   PMID:29459677   PMID:29878302   PMID:29959233  
PMID:30389720   PMID:30550785   PMID:30595499   PMID:30689641   PMID:30923192   PMID:31040226   PMID:31220272   PMID:31410202   PMID:31823782   PMID:32325033  


Genomics

Comparative Map Data
Dsp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391338,335,270 - 38,382,553 (+)NCBIGRCm39mm39
GRCm39 Ensembl1338,335,270 - 38,382,553 (+)Ensembl
GRCm381338,151,294 - 38,198,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1338,151,294 - 38,198,577 (+)EnsemblGRCm38mm10GRCm38
MGSCv371338,243,163 - 38,290,446 (+)NCBIGRCm37mm9NCBIm37
MGSCv361338,158,760 - 38,206,043 (+)NCBImm8
Celera1339,265,897 - 39,313,259 (+)NCBICelera
Cytogenetic Map13A3.3NCBI
DSP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl67,541,617 - 7,586,714 (+)EnsemblGRCh38hg38GRCh38
GRCh3867,541,671 - 7,586,714 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3767,541,904 - 7,586,947 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3667,486,869 - 7,531,945 (+)NCBINCBI36hg18NCBI36
Build 3467,486,868 - 7,531,945NCBI
Celera68,771,623 - 8,816,711 (+)NCBI
Cytogenetic Map6p24.3NCBI
HuRef67,419,476 - 7,464,417 (+)NCBIHuRef
CHM1_167,544,023 - 7,589,106 (+)NCBICHM1_1
Dsp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21726,623,602 - 26,671,692 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1726,623,588 - 26,671,800 (-)Ensembl
Rnor_6.01727,286,811 - 27,334,453 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1727,286,796 - 27,334,379 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01729,201,872 - 29,249,490 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41732,848,313 - 32,896,044 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11732,851,800 - 32,898,885 (-)NCBI
Celera1726,257,726 - 26,305,766 (-)NCBICelera
Cytogenetic Map17p12NCBI
Dsp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554656,356,863 - 6,392,207 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554656,356,970 - 6,391,206 (-)NCBIChiLan1.0ChiLan1.0
DSP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.167,664,399 - 7,709,391 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl67,664,211 - 7,709,391 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v067,381,046 - 7,426,408 (+)NCBIMhudiblu_PPA_v0panPan3
DSP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1357,479,628 - 7,524,732 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl357,479,643 - 7,524,044 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha357,483,107 - 7,528,345 (+)NCBI
ROS_Cfam_1.0357,562,265 - 7,607,463 (+)NCBI
UMICH_Zoey_3.1357,415,316 - 7,460,024 (+)NCBI
UNSW_CanFamBas_1.0357,441,523 - 7,486,395 (+)NCBI
UU_Cfam_GSD_1.0358,773,585 - 8,819,012 (+)NCBI
LOC101968918
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494616,760,022 - 16,807,481 (-)NCBI
SpeTri2.0NW_0049365345,029,008 - 5,076,467 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl74,862,649 - 4,915,615 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.174,862,649 - 4,915,626 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.274,968,344 - 5,021,222 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103222210
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11764,611,243 - 64,656,297 (-)NCBI
ChlSab1.1 Ensembl1764,611,103 - 64,656,366 (-)Ensembl
Vero_WHO_p1.0NW_0236660447,495,774 - 7,541,054 (+)NCBI
Dsp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475618,036,103 - 18,083,379 (-)NCBI

Position Markers
AW109828  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381338,198,335 - 38,198,472UniSTSGRCm38
MGSCv371338,290,204 - 38,290,341UniSTSGRCm37
Celera1339,313,016 - 39,313,153UniSTS
Cytogenetic Map13A3.3UniSTS
Whitehead/MRC_RH13409.72UniSTS
RH124644  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381338,198,306 - 38,198,571UniSTSGRCm38
MGSCv371338,290,175 - 38,290,440UniSTSGRCm37
Celera1339,312,987 - 39,313,253UniSTS
Cytogenetic Map13A3.3UniSTS
RH125744  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381338,198,278 - 38,198,495UniSTSGRCm38
MGSCv371338,290,147 - 38,290,364UniSTSGRCm37
Celera1339,312,959 - 39,313,176UniSTS
Cytogenetic Map13A3.3UniSTS
Whitehead/MRC_RH13409.57UniSTS
Dsp  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3823,780,346 - 3,781,238UniSTSGRCm38
MGSCv3723,697,618 - 3,698,510UniSTSGRCm37
Celera23,731,390 - 3,732,282UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map13A3.3UniSTS
cM Map13 UniSTS
LSCV12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381338,161,385 - 38,161,851UniSTSGRCm38
MGSCv371338,253,254 - 38,253,720UniSTSGRCm37
Celera1339,276,040 - 39,276,506UniSTS
Cytogenetic Map13A3.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13390000075900000Mouse
1558898Hpi1_mhapatic PMN infiltration 1 (mouse)Not determined13436402652947604Mouse
10402494Igmsc1_mimmunoglobulin M secreting cells 1 (mouse)Not determined131699396044765084Mouse
1301984Pbd2_mpeak bone density 2 (mouse)Not determined131701492338763430Mouse
1301880Hypt_mhypertension (mouse)Not determined131797280951972941Mouse
13463469Gssq1_mglomerulosclerosis severity QTL 1 (mouse)131887692552877067Mouse
12880423V25Dq7_mvitamin D inactive form serum level QTL 7 (mouse)131940000053400000Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132029344259673791Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20293442112761890Mouse
1357591Tesq1_mtestis weight QTL 1 (mouse)Not determined132043134255572704Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132043134272237070Mouse
10045618Heal17_mwound healing/regeneration 17 (mouse)Not determined132056296354563080Mouse
1558844Lith15_mlithogenic gene 15 (mouse)Not determined132176326255763430Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2568305359683053Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132776499361765084Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132805696662057068Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132806390362064039Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132806390362064039Mouse
10755517Chol15_mcholesterol 15 (mouse)133081599164815991Mouse
10755533Chol18_mcholesterol 18 (mouse)133081599164815991Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133097563464975634Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133119126065191260Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133476790768768045Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133587692596102654Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133594749469947604Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133594749469947604Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133599078469990868Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:475
Count of miRNA genes:264
Interacting mature miRNAs:301
Transcripts:ENSMUST00000124830, ENSMUST00000127906, ENSMUST00000145151
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000124830   ⟹   ENSMUSP00000115062
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1338,335,270 - 38,382,553 (+)Ensembl
GRCm38.p6 Ensembl1338,151,294 - 38,198,577 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127906   ⟹   ENSMUSP00000117252
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1338,335,304 - 38,382,553 (+)Ensembl
GRCm38.p6 Ensembl1338,151,328 - 38,198,577 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145151
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1338,362,343 - 38,366,210 (+)Ensembl
GRCm38.p6 Ensembl1338,178,367 - 38,182,234 (+)Ensembl
RefSeq Acc Id: NM_023842   ⟹   NP_076331
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391338,335,270 - 38,382,553 (+)NCBI
GRCm381338,151,294 - 38,198,577 (+)NCBI
MGSCv371338,243,163 - 38,290,446 (+)RGD
Celera1339,265,897 - 39,313,259 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006516532   ⟹   XP_006516595
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391338,335,354 - 38,382,230 (+)NCBI
GRCm381338,151,391 - 38,198,577 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_076331 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516595 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF02527 (Get FASTA)   NCBI Sequence Viewer  
  BAB26020 (Get FASTA)   NCBI Sequence Viewer  
  BAC36872 (Get FASTA)   NCBI Sequence Viewer  
  E9Q557 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_076331   ⟸   NM_023842
- UniProtKB: E9Q557 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006516595   ⟸   XM_006516532
- Peptide Label: isoform X1
- UniProtKB: E9PZW0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000115062   ⟸   ENSMUST00000124830
RefSeq Acc Id: ENSMUSP00000117252   ⟸   ENSMUST00000127906
Protein Domains
SH3

Promoters
RGD ID:8680126
Promoter ID:EPDNEW_M18094
Type:initiation region
Name:Dsp_1
Description:Mus musculus desmoplakin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381338,151,382 - 38,151,442EPDNEW
RGD ID:6823824
Promoter ID:MM_KWN:13851
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:NM_023842,   OTTMUST00000081067
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361338,243,031 - 38,243,531 (+)MPROMDB
RGD ID:6823825
Promoter ID:MM_KWN:13854
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ENSMUST00000110228
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361338,284,706 - 38,285,206 (+)MPROMDB
RGD ID:6823820
Promoter ID:MM_KWN:13855
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000068162
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361338,289,071 - 38,289,571 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109611 AgrOrtholog
Ensembl Genes ENSMUSG00000054889 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000115062 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000117252 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000124830 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000127906 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.90.1290.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Desmoplakin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Desmoplakin_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Desmoplakin_Spectrin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plakin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plakin_repeat_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plectin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:109620 UniProtKB/Swiss-Prot
MGD MGI:109611 ENTREZGENE
NCBI Gene 109620 ENTREZGENE
PANTHER PTHR23169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23169:SF26 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Plectin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB DSP RGD
PhenoGen Dsp PhenoGen
PROSITE SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PLEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF75399 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DESP_MOUSE UniProtKB/Swiss-Prot
  E9PZW0 ENTREZGENE, UniProtKB/TrEMBL
  E9Q557 ENTREZGENE
  Q8BP77_MOUSE UniProtKB/TrEMBL
  Q9CV95_MOUSE UniProtKB/TrEMBL
  Q9QZX5_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Dsp  desmoplakin  5730453H04Rik  RIKEN cDNA 5730453H04 gene  Data Merged 737654 PROVISIONAL