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Gene: Rps6kb1 (ribosomal protein S6 kinase, polypeptide 1) Mus musculus
Symbol: Rps6kb1
Name: ribosomal protein S6 kinase, polypeptide 1
Description: Exhibits protein kinase activity. Involved in several processes, including behavioral fear response; cellular response to hormone stimulus; and protein kinase B signaling. Localizes to the mitochondrion. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; olfactory epithelium; and retina nuclear layer. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1); PARTICIPATES IN mTOR signaling pathway; acute myeloid leukemia pathway; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 14-Deoxy-11,12-didehydroandrographolide; 15-deoxy-Delta(12,14)-prostaglandin J2; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610318I15Rik; 4732464A07Rik; 70 kDa ribosomal protein S6 kinase 1; 70kDa; AA959758; AI256796; AI314060; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA; p70-S6K 1; p70/85s6k; p70s6k; P70S6K1; ribosomal protein S6 kinase beta-1; ribosomal protein S6 kinase I; ribosomal protein S6 kinase, 70kD, polypeptide 1; S6K; S6K-beta-1; S6K1
Homo sapiens (human) : RPS6KB1 (ribosomal protein S6 kinase B1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rps6kb1 (ribosomal protein S6 kinase B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6kb1 (ribosomal protein S6 kinase B1)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KB1 (ribosomal protein S6 kinase B1)
Canis lupus familiaris (dog) : RPS6KB1 (ribosomal protein S6 kinase B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6kb1 (ribosomal protein S6 kinase B1)
Sus scrofa (pig) : RPS6KB1 (ribosomal protein S6 kinase B1)
Chlorocebus sabaeus (green monkey) : RPS6KB1 (ribosomal protein S6 kinase B1)
Heterocephalus glaber (naked mole-rat) : Rps6kb1 (ribosomal protein S6 kinase B1)
more info ...
Related Pseudogenes: Gm21046  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1186,498,871 - 86,544,805 (-)Ensembl
GRCm381186,498,869 - 86,544,885 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371186,312,511 - 86,358,309 (-)NCBIGRCm37mm9NCBIm37
MGSCv361186,330,178 - 86,360,969 (-)NCBImm8
Celera1196,115,093 - 96,160,675 (-)NCBICelera
Cytogenetic Map11 CNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rps6kb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731645
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.