Tjp2 (tight junction protein 2) - Rat Genome Database

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Gene: Tjp2 (tight junction protein 2) Mus musculus
Analyze
Symbol: Tjp2
Name: tight junction protein 2
RGD ID: 733147
MGI Page MGI
Description: Predicted to have several functions, including cell adhesion molecule binding activity; protein C-terminus binding activity; and protein tyrosine kinase binding activity. Involved in TNFSF11-mediated signaling pathway and negative regulation of osteoclast development. Localizes to nucleus; plasma membrane; and tight junction. Is expressed in several structures, including early embryo; genitourinary system; inner ear; lower jaw tooth; and neural ectoderm. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 51; disease of metabolism; and progressive familial intrahepatic cholestasis 4. Orthologous to human TJP2 (tight junction protein 2); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: tight junction protein ZO-2; Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2); ZO-; ZO-2; zona occludens protein 2; zonula occludens protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391924,071,860 - 24,202,492 (-)NCBIGRCm39mm39
GRCm39 Ensembl1924,071,869 - 24,202,394 (-)Ensembl
GRCm381924,094,496 - 24,225,128 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1924,094,505 - 24,225,030 (-)EnsemblGRCm38mm10GRCm38
MGSCv371924,168,992 - 24,299,444 (-)NCBIGRCm37mm9NCBIm37
MGSCv361924,161,608 - 24,241,085 (-)NCBImm8
Celera1924,858,437 - 24,990,672 (-)NCBICelera
Cytogenetic Map19BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
calcitriol  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenzo[a,l]pyrene  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
finasteride  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
glucose  (EXP)
glycyrrhizinic acid  (EXP)
hexadecanoic acid  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
levofloxacin  (ISO)
lipopolysaccharide  (ISO)
malaoxon  (ISO)
malathion  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methylmercury chloride  (ISO)
N-acetyl-L-cysteine  (EXP)
okadaic acid  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
rifampicin  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
streptozocin  (EXP)
sulindac  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)

References

Additional References at PubMed
PMID:8889548   PMID:10026224   PMID:10349636   PMID:10512203   PMID:10601346   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12023291   PMID:12060405  
PMID:12403786   PMID:12477932   PMID:12507281   PMID:12520002   PMID:12829691   PMID:12904583   PMID:14576355   PMID:14610273   PMID:15292177   PMID:15489334   PMID:15747579   PMID:15782199  
PMID:15840001   PMID:16141072   PMID:16141073   PMID:16452087   PMID:16601135   PMID:16650609   PMID:16923393   PMID:17507402   PMID:17967808   PMID:18086565   PMID:18172007   PMID:18287559  
PMID:18353970   PMID:18423437   PMID:18596233   PMID:18799693   PMID:18817772   PMID:19407242   PMID:19538286   PMID:19692573   PMID:20223754   PMID:20602916   PMID:20704721   PMID:20868367  
PMID:21074523   PMID:21074722   PMID:21186337   PMID:21267068   PMID:21601268   PMID:21677750   PMID:21873635   PMID:21976438   PMID:22437732   PMID:23034938   PMID:23195221   PMID:23213408  
PMID:23406901   PMID:23826934   PMID:23885123   PMID:24375017   PMID:24457600   PMID:24889144   PMID:24905925   PMID:25486565   PMID:25742799   PMID:25762570   PMID:25813538   PMID:26258622  
PMID:26365490   PMID:26609154   PMID:28323616   PMID:28420508   PMID:29254152   PMID:29845705   PMID:30291936   PMID:32581705   PMID:33184034  


Genomics

Comparative Map Data
Tjp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391924,071,860 - 24,202,492 (-)NCBIGRCm39mm39
GRCm39 Ensembl1924,071,869 - 24,202,394 (-)Ensembl
GRCm381924,094,496 - 24,225,128 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1924,094,505 - 24,225,030 (-)EnsemblGRCm38mm10GRCm38
MGSCv371924,168,992 - 24,299,444 (-)NCBIGRCm37mm9NCBIm37
MGSCv361924,161,608 - 24,241,085 (-)NCBImm8
Celera1924,858,437 - 24,990,672 (-)NCBICelera
Cytogenetic Map19BNCBI
TJP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl969,121,264 - 69,274,615 (+)EnsemblGRCh38hg38GRCh38
GRCh38969,121,006 - 69,255,208 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37971,736,180 - 71,870,124 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36970,978,909 - 71,059,940 (+)NCBINCBI36hg18NCBI36
Build 34969,018,642 - 69,099,672NCBI
Celera942,332,221 - 42,460,614 (+)NCBI
Cytogenetic Map9q21.11NCBI
HuRef941,580,602 - 41,709,784 (+)NCBIHuRef
CHM1_1971,882,855 - 72,016,570 (+)NCBICHM1_1
Tjp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21221,709,745 - 221,838,383 (-)NCBI
Rnor_6.0 Ensembl1241,945,841 - 242,083,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01241,945,816 - 242,084,044 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01249,224,590 - 249,358,779 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,475,386 - 227,574,457 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11227,639,414 - 227,668,771 (-)NCBI
Celera1218,921,753 - 219,049,897 (-)NCBICelera
Cytogenetic Map1q51NCBI
Tjp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554343,781,368 - 3,923,240 (-)NCBIChiLan1.0ChiLan1.0
TJP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1967,865,958 - 68,020,569 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0955,536,627 - 55,690,472 (-)NCBIMhudiblu_PPA_v0panPan3
TJP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1188,126,134 - 88,251,018 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl188,126,136 - 88,230,654 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha188,593,804 - 88,698,045 (-)NCBI
ROS_Cfam_1.0188,673,963 - 88,797,946 (-)NCBI
UMICH_Zoey_3.1188,329,360 - 88,433,088 (-)NCBI
UNSW_CanFamBas_1.0188,035,802 - 88,139,746 (-)NCBI
UU_Cfam_GSD_1.0188,799,691 - 88,904,715 (-)NCBI
Tjp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947135,633,106 - 135,729,071 (-)NCBI
SpeTri2.0NW_0049365035,414,330 - 5,539,895 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TJP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11222,474,518 - 222,612,989 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21248,714,644 - 248,883,729 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TJP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11280,224,497 - 80,358,495 (+)NCBI
Vero_WHO_p1.0NW_02366603868,660,986 - 68,767,811 (+)NCBI
Tjp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247363,833,402 - 4,009,385 (-)NCBI

Position Markers
D19Mit107  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381924,226,326 - 24,226,443UniSTSGRCm38
MGSCv371924,300,816 - 24,300,933UniSTSGRCm37
Celera1924,992,044 - 24,992,163UniSTS
Celera1924,992,044 - 24,993,183UniSTS
Cytogenetic Map19C1UniSTS
cM Map1922.0UniSTS
Whitehead Genetic1917.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301271Datd_mdopamine transporter density (mouse)Not determined19132362870Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132897810Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19167640035676563Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19320000035900000Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19334585237345984Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19334585237345984Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19334585237345984Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19334585237345984Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19533596239336106Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19932831543328421Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19981005343810202Mouse
14928311Manh85_mmandible shape 85 (mouse)191193738945937389Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191494561648945738Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191593520749935319Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191593520749935319Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191831776252317981Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191831776252317981Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192025691554257062Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192025691554257062Mouse
1301197Tlyr1_mthymic lymphoma resistance 1 (mouse)Not determined192056216425336432Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192139025755390480Mouse
1357596Tgct3_mtesticular germ cell tumor 3 (mouse)Not determined192200672732935319Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192233596253923073Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:321
Count of miRNA genes:250
Interacting mature miRNAs:283
Transcripts:ENSMUST00000099558
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001198985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001376368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030250861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036161512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC107685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC149224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF113005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM224980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP767126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ033995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ176958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY032291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY073294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB724174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF736959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN527767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN529621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000099558   ⟹   ENSMUSP00000097154
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1924,094,523 - 24,225,026 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232956   ⟹   ENSMUSP00000156896
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1924,094,505 - 24,225,030 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233027   ⟹   ENSMUSP00000156605
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1924,094,505 - 24,174,189 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233658   ⟹   ENSMUSP00000156728
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1924,094,505 - 24,200,650 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236570   ⟹   ENSMUSP00000157619
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1924,131,315 - 24,143,082 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237550   ⟹   ENSMUSP00000157949
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1924,134,860 - 24,173,136 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237937
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1924,132,528 - 24,147,067 (-)Ensembl
RefSeq Acc Id: NM_001198985   ⟹   NP_001185914
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,071,866 - 24,151,553 (-)NCBI
GRCm381924,094,502 - 24,174,189 (-)NCBI
Celera1924,858,437 - 24,990,744 (-)ENTREZGENE
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001360391   ⟹   NP_001347320
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,071,866 - 24,120,446 (-)NCBI
GRCm381924,094,502 - 24,143,082 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001360392   ⟹   NP_001347321
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,071,866 - 24,202,492 (-)NCBI
GRCm381924,094,502 - 24,225,128 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001376368   ⟹   NP_001363297
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,071,860 - 24,202,390 (-)NCBI
GRCm381924,094,496 - 24,225,026 (-)NCBI
RefSeq Acc Id: NM_011597   ⟹   NP_035727
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,071,866 - 24,202,492 (-)NCBI
GRCm381924,094,502 - 24,225,128 (-)NCBI
MGSCv371924,168,992 - 24,299,444 (-)RGD
Celera1924,858,437 - 24,990,744 (-)ENTREZGENE
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006526904   ⟹   XP_006526967
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,072,006 - 24,124,428 (-)NCBI
GRCm381924,094,642 - 24,147,122 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006526907   ⟹   XP_006526970
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,072,010 - 24,124,303 (-)NCBI
GRCm381924,094,646 - 24,146,939 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006526909   ⟹   XP_006526972
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,072,006 - 24,120,441 (-)NCBI
GRCm381924,094,642 - 24,146,765 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017318136   ⟹   XP_017173625
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,072,006 - 24,171,222 (-)NCBI
GRCm381924,094,642 - 24,193,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030250861   ⟹   XP_030106721
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,072,006 - 24,151,690 (-)NCBI
GRCm381924,094,642 - 24,174,328 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036161512   ⟹   XP_036017405
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391924,072,006 - 24,171,222 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_035727   ⟸   NM_011597
- Peptide Label: isoform 2
- UniProtKB: Q9Z0U1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001185914   ⟸   NM_001198985
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: XP_006526972   ⟸   XM_006526909
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006526970   ⟸   XM_006526907
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006526967   ⟸   XM_006526904
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017173625   ⟸   XM_017318136
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: NP_001347321   ⟸   NM_001360392
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001347320   ⟸   NM_001360391
- Peptide Label: isoform 3
RefSeq Acc Id: XP_030106721   ⟸   XM_030250861
- Peptide Label: isoform X5
RefSeq Acc Id: NP_001363297   ⟸   NM_001376368
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000157949   ⟸   ENSMUST00000237550
RefSeq Acc Id: ENSMUSP00000097154   ⟸   ENSMUST00000099558
RefSeq Acc Id: ENSMUSP00000157619   ⟸   ENSMUST00000236570
RefSeq Acc Id: ENSMUSP00000156728   ⟸   ENSMUST00000233658
RefSeq Acc Id: ENSMUSP00000156605   ⟸   ENSMUST00000233027
RefSeq Acc Id: ENSMUSP00000156896   ⟸   ENSMUST00000232956
RefSeq Acc Id: XP_036017405   ⟸   XM_036161512
- Peptide Label: isoform X3
Protein Domains
Guanylate kinase-like   PDZ   SH3

Promoters
RGD ID:13679130
Promoter ID:EPDNEW_M23714
Type:initiation region
Name:Tjp2_1
Description:Mus musculus tight junction protein 2 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381924,225,026 - 24,225,086EPDNEW
RGD ID:6830472
Promoter ID:MM_KWN:26693
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung
Transcripts:ENSMUST00000099558,   UC008HAL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361924,248,489 - 24,248,989 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1341872 AgrOrtholog
Ensembl Genes ENSMUSG00000024812 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000097154 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000156605 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000156728 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000156896 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000157619 UniProtKB/TrEMBL
  ENSMUSP00000157949 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000099558 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000232956 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000233027 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000233658 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000236570 UniProtKB/TrEMBL
  ENSMUST00000237550 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GK/Ca_channel_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Guanylate_kin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPR005417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZO-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZO-2_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21873 UniProtKB/Swiss-Prot
MGD MGI:1341872 ENTREZGENE
NCBI Gene 21873 ENTREZGENE
Pfam Guanylate_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tjp2 PhenoGen
PRINTS ZONOCCLUDNS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZONOCCLUDNS2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GUANYLATE_KINASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GuKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B2WBH9_MOUSE UniProtKB/TrEMBL
  A0A3B2WCN9_MOUSE UniProtKB/TrEMBL
  A0A494B9E6_MOUSE UniProtKB/TrEMBL
  A0A494BAA0_MOUSE UniProtKB/TrEMBL
  Q9Z0U1 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8K210 UniProtKB/Swiss-Prot