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Gene: Flt3l (FMS-like tyrosine kinase 3 ligand) Mus musculus
Symbol: Flt3l
Name: FMS-like tyrosine kinase 3 ligand
Description: Exhibits protein homodimerization activity and receptor tyrosine kinase binding activity. Involved in several processes, including positive regulation of cell differentiation; positive regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Localizes to the extracellular space and intrinsic component of external side of plasma membrane. Human ortholog(s) of this gene implicated in colon carcinoma; glioblastoma multiforme; and malignant glioma. Is expressed in several structures, including central nervous system; liver; retina; spleen; and yolk sac. Orthologous to human FLT3LG (fms related tyrosine kinase 3 ligand); INTERACTS WITH 3,4-methylenedioxymethamphetamine; acrolein; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: flt3 ligand; Flt3lg; fms-related tyrosine kinase 3 ligand; Ly72L; SL cytokine
Homo sapiens (human) : FLT3LG (fms related tyrosine kinase 3 ligand)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Flt3lg (fms-related tyrosine kinase 3 ligand)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flt3lg (fms related tyrosine kinase 3 ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : FLT3LG (fms related tyrosine kinase 3 ligand)
Canis lupus familiaris (dog) : FLT3LG (fms related tyrosine kinase 3 ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flt3lg (fms related tyrosine kinase 3 ligand)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38745,131,183 - 45,136,490 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37752,386,559 - 52,391,802 (-)NCBIGRCm37mm9NCBIm37
MGSCv36744,999,456 - 45,004,327 (-)NCBImm8
Celera740,584,281 - 40,589,522 (-)NCBICelera
Cytogenetic Map7 B3NCBI
cM Map729.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Flt3l
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557069
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.